psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:Q29	N:N:K22	4.07	No	No	0	3	1
2	L:L:Q29	N:N:E23	11.47	No	No	0	3	4
3	L:L:C31	L:L:P32	1.88	No	No	0	9	5
4	L:L:C31	L:L:C55	7.28	No	No	0	9	9
5	L:L:C31	N:N:R26	2.79	No	No	0	9	5
6	L:L:E33	N:N:R26	4.65	No	No	0	7	5
7	L:L:C34	L:L:G54	1.96	No	No	5	9	9
8	L:L:C34	L:L:C84	7.28	No	Yes	5	9	9
9	L:L:C106	L:L:C34	1.82	Yes	No	5	9	9
10	L:L:L36	L:L:T35	5.9	No	No	0	9	5
11	L:L:L36	L:L:L50	5.54	No	No	5	9	5
12	L:L:H103	L:L:L36	7.71	Yes	No	5	9	9
13	L:L:M53	L:L:Q37	10.88	No	No	0	4	4
14	L:L:N39	L:L:P40	9.77	Yes	No	0	8	1
15	L:L:F41	L:L:N39	10.87	No	Yes	6	1	8
16	L:L:F42	L:L:N39	8.46	Yes	Yes	6	6	8
17	L:L:N39	L:L:S43	4.47	Yes	No	0	8	8
18	L:L:I49	L:L:N39	9.91	Yes	Yes	6	5	8
19	L:L:N39	N:N:V64	5.91	Yes	Yes	6	8	6
20	L:L:F41	L:L:F42	6.43	No	Yes	6	1	6
21	L:L:F41	N:N:V64	2.62	No	Yes	6	1	6
22	L:L:F42	L:L:Q44	3.51	Yes	Yes	6	6	3
23	L:L:F42	L:L:I49	3.77	Yes	Yes	6	6	5
24	L:L:F42	L:L:V94	9.18	Yes	No	6	6	3
25	L:L:F42	L:L:V100	2.62	Yes	No	6	6	5
26	L:L:F42	N:N:L65	9.74	Yes	No	6	6	2
27	L:L:P48	L:L:S43	3.56	No	No	0	6	8
28	L:L:I49	L:L:Q44	2.74	Yes	Yes	6	5	3
29	L:L:Q44	L:L:V94	4.3	Yes	No	6	3	3
30	L:L:A47	L:L:G46	1.95	No	No	0	5	6
31	L:L:A47	L:L:P48	1.87	No	No	0	5	6
32	L:L:I49	L:L:V92	3.07	Yes	No	0	5	4
33	L:L:L50	L:L:N102	12.36	No	No	0	5	9
34	L:L:H103	L:L:L50	5.14	Yes	No	5	9	5
35	L:L:M53	L:L:Q51	5.44	No	No	0	4	9
36	L:L:Q51	N:N:V64	7.16	No	Yes	0	9	6
37	L:L:C52	L:L:C84	1.82	Yes	Yes	5	9	9
38	L:L:A86	L:L:C52	3.61	No	Yes	5	9	9
39	L:L:C52	L:L:H103	11.79	Yes	Yes	5	9	9
40	L:L:C106	L:L:C52	5.46	Yes	Yes	5	9	9
41	L:L:C84	L:L:G54	3.92	Yes	No	5	9	9
42	L:L:C55	N:N:Y57	8.06	No	Yes	0	9	6
43	L:L:C56	L:L:T82	6.76	No	No	18	9	8
44	L:L:C108	L:L:C56	7.28	No	No	18	9	9
45	L:L:F57	L:L:R59	16.03	Yes	No	0	7	8
46	L:L:F57	N:N:A55	2.77	Yes	No	7	7	8
47	L:L:F57	N:N:G56	4.52	Yes	No	7	7	9
48	L:L:F57	N:N:Y57	2.06	Yes	Yes	0	7	6
49	L:L:S58	N:N:Y57	2.54	No	Yes	0	9	6
50	L:L:E80	L:L:R59	6.98	No	No	0	9	8
51	L:L:A60	L:L:S79	3.42	No	No	9	9	9
52	L:L:A60	N:N:Y79	2.67	No	Yes	9	9	8
53	L:L:P62	L:L:Y61	18.08	No	Yes	7	9	8
54	L:L:Y61	N:N:A34	6.67	Yes	No	7	8	7
55	L:L:Y61	N:N:L36	9.38	Yes	No	7	8	7
56	L:L:Y61	N:N:T51	3.75	Yes	Yes	7	8	9
57	L:L:Y61	N:N:I53	13.3	Yes	Yes	7	8	8
58	L:L:Y61	N:N:L128	4.69	Yes	No	0	8	5
59	L:L:P62	N:N:L36	19.7	No	No	7	9	7
60	L:L:P64	L:L:T63	3.5	No	Yes	2	9	9
61	L:L:S67	L:L:T63	6.4	Yes	Yes	2	7	9
62	L:L:K75	L:L:T63	12.01	No	Yes	0	9	9
63	L:L:T63	L:L:T78	7.85	Yes	No	0	9	9
64	L:L:P64	L:L:S67	8.91	No	Yes	2	9	7
65	L:L:P64	N:N:A37	1.87	No	No	2	9	7
66	L:L:L65	N:N:E39	14.58	No	No	0	6	9
67	L:L:L65	N:N:E41	11.93	No	Yes	0	6	6
68	L:L:R66	R:R:Y58	6.17	No	Yes	0	6	5
69	L:L:S67	N:N:H126	2.79	Yes	Yes	2	7	3
70	L:L:S67	R:R:Y58	5.09	Yes	Yes	2	7	5
71	L:L:K68	L:L:K75	7.18	No	No	0	6	9
72	L:L:K68	N:N:E41	9.45	No	Yes	0	6	6
73	L:L:K69	N:N:E41	2.7	No	Yes	0	5	6
74	L:L:K69	R:R:D84	4.15	No	No	0	5	7
75	L:L:K69	R:R:K109	7.18	No	No	0	5	6
76	L:L:T70	R:R:Q82	9.92	No	Yes	2	9	6
77	L:L:T70	R:R:D84	2.89	No	No	0	9	7
78	L:L:T70	R:R:N107	2.92	No	Yes	2	9	7
79	L:L:K75	L:L:M71	17.28	No	No	0	9	9
80	L:L:M71	N:N:D119	5.54	No	Yes	2	9	9
81	L:L:M71	R:R:N107	5.61	No	Yes	2	9	7
82	L:L:L72	L:L:V73	4.47	Yes	No	15	3	7
83	L:L:L72	R:R:K109	8.46	Yes	No	0	3	6
84	L:L:L72	R:R:N132	6.87	Yes	No	15	3	8
85	L:L:L72	R:R:D157	2.71	Yes	Yes	15	3	6
86	L:L:V73	R:R:N132	2.96	No	No	15	7	8
87	L:L:V73	R:R:D157	5.84	No	Yes	15	7	6
88	L:L:V77	N:N:Y79	15.14	No	Yes	0	9	8
89	L:L:V77	N:N:T118	7.93	No	No	0	9	8
90	L:L:T78	N:N:H126	5.48	No	Yes	0	9	3
91	L:L:S79	N:N:N78	2.98	No	No	9	9	8
92	L:L:S79	N:N:Y79	2.54	No	Yes	9	9	8
93	L:L:E80	N:N:P123	3.14	No	Yes	0	9	4
94	L:L:E80	N:N:D125	3.9	No	No	0	9	4
95	L:L:S81	N:N:V76	8.08	No	No	0	9	8
96	L:L:C108	L:L:T82	6.76	No	No	18	9	8
97	L:L:T82	N:N:P123	3.5	No	Yes	0	8	4
98	L:L:C111	L:L:C83	7.28	No	No	0	9	9
99	L:L:C83	N:N:Q74	4.58	No	No	0	9	9
100	L:L:C106	L:L:C84	3.64	Yes	Yes	5	9	9
101	L:L:V85	L:L:Y112	12.62	No	No	0	9	5
102	L:L:A86	L:L:Y89	4	No	No	0	9	4
103	L:L:A86	L:L:H103	4.39	No	Yes	5	9	9
104	L:L:K87	L:L:S88	3.06	No	No	0	5	4
105	L:L:H107	L:L:K87	2.62	No	No	0	8	5
106	L:L:E101	L:L:Y89	2.24	No	No	0	5	4
107	L:L:Y89	R:R:K126	2.39	No	Yes	0	4	5
108	L:L:N102	L:L:V92	4.43	No	No	0	9	4
109	L:L:V100	L:L:V94	4.81	No	No	6	5	3
110	L:L:G96	L:L:M95	3.49	No	No	0	3	3
111	L:L:G96	L:L:G97	2.11	No	No	0	3	4
112	L:L:F98	L:L:K99	2.48	No	No	0	3	3
113	L:L:F98	N:N:V68	5.24	No	No	0	3	2
114	L:L:F98	R:R:F335	6.43	No	No	0	3	1
115	L:L:V100	N:N:L65	5.96	No	No	6	5	2
116	L:L:E101	N:N:Q66	5.1	No	No	0	5	5
117	L:L:C106	L:L:H103	7.37	Yes	Yes	5	9	9
118	L:L:S109	R:R:K77	4.59	No	Yes	0	8	5
119	L:L:T110	L:L:Y112	4.99	No	No	0	9	5
120	L:L:T110	R:R:K77	3	No	Yes	19	9	5
121	L:L:T110	R:R:E102	4.23	No	Yes	19	9	7
122	L:L:C111	L:L:H114	8.85	No	No	0	9	8
123	L:L:Y112	R:R:Y127	31.77	No	Yes	0	5	6
124	L:L:Y113	N:N:A71	5.34	No	No	0	4	3
125	L:L:Y113	N:N:P73	6.95	No	Yes	0	4	2
126	L:L:Y113	R:R:K180	2.39	No	Yes	0	4	5
127	L:L:H114	L:L:K115	10.48	No	Yes	0	8	9
128	L:L:H114	N:N:G121	4.77	No	No	0	8	7
129	L:L:K115	R:R:Q106	2.71	Yes	Yes	2	9	7
130	L:L:K115	R:R:C131	3.23	Yes	Yes	2	9	7
131	L:L:K115	R:R:E154	4.05	Yes	No	0	9	7
132	L:L:S116	N:N:P73	1.78	No	Yes	3	9	2
133	L:L:S116	N:N:L112	12.01	No	No	3	9	4
134	L:L:S116	R:R:Y182	2.54	No	Yes	3	9	6
135	N:N:K22	N:N:R30	2.48	No	No	0	1	5
136	N:N:E23	N:N:P24	3.14	No	No	0	4	3
137	N:N:C29	N:N:C77	7.28	No	No	0	9	9
138	N:N:C108	N:N:C29	1.82	No	No	0	9	9
139	N:N:P31	N:N:R30	2.88	No	No	0	7	5
140	N:N:P31	N:N:T52	5.25	No	No	0	7	8
141	N:N:C108	N:N:P31	9.41	No	No	0	9	7
142	N:N:I32	N:N:I53	5.89	No	Yes	0	5	8
143	N:N:A34	N:N:I53	4.87	No	Yes	7	7	8
144	N:N:T35	N:N:T48	4.71	No	No	0	8	5
145	N:N:L36	N:N:T51	5.9	No	Yes	7	7	9
146	N:N:A37	N:N:C46	1.81	No	No	2	7	9
147	N:N:A37	N:N:C130	1.81	No	Yes	2	7	9
148	N:N:I47	N:N:V38	3.07	No	No	0	6	8
149	N:N:V100	N:N:V38	4.81	No	No	0	6	8
150	N:N:C46	N:N:E39	13.67	No	No	0	9	9
151	N:N:E41	N:N:K40	4.05	Yes	No	0	6	7
152	N:N:G42	N:N:V96	1.84	No	No	0	7	7
153	N:N:C43	N:N:P44	1.88	No	No	10	9	6
154	N:N:C43	N:N:C92	7.28	No	Yes	10	9	9
155	N:N:C43	N:N:P93	3.77	No	No	10	9	5
156	N:N:P44	N:N:P93	5.84	No	No	10	6	5
157	N:N:I47	N:N:V45	3.07	No	No	0	6	3
158	N:N:C130	N:N:C46	7.28	Yes	No	2	9	9
159	N:N:T51	N:N:Y102	2.5	Yes	No	0	9	6
160	N:N:T52	N:N:V104	3.17	No	No	0	8	9
161	N:N:A55	N:N:I53	3.25	No	Yes	7	8	8
162	N:N:C54	N:N:C77	1.82	Yes	No	0	9	9
163	N:N:C54	N:N:Y79	10.75	Yes	Yes	9	9	8
164	N:N:A105	N:N:C54	1.81	No	Yes	9	9	9
165	N:N:C108	N:N:C54	7.28	No	Yes	0	9	9
166	N:N:A55	N:N:G56	1.95	No	No	7	8	9
167	N:N:T60	N:N:Y57	7.49	No	Yes	0	9	6
168	N:N:C58	N:N:P59	5.65	No	No	0	9	2
169	N:N:C58	N:N:V75	5.12	No	No	20	9	4
170	N:N:C110	N:N:C58	7.28	No	No	20	9	9
171	N:N:Q74	N:N:T60	5.67	No	No	0	9	9
172	N:N:L69	N:N:R63	7.29	No	No	0	3	4
173	N:N:L72	N:N:R63	2.43	No	No	0	3	4
174	N:N:R63	R:R:Y331	2.06	No	No	0	4	1
175	N:N:L65	N:N:V64	2.98	No	Yes	6	2	6
176	N:N:G67	N:N:V68	1.84	No	No	0	4	2
177	N:N:L69	N:N:P70	4.93	No	No	0	3	4
178	N:N:P70	R:R:R247	2.88	No	Yes	0	4	5
179	N:N:L72	N:N:P73	4.93	No	Yes	0	3	2
180	N:N:L112	N:N:P73	6.57	No	Yes	3	4	2
181	N:N:C110	N:N:V75	6.83	No	No	20	9	4
182	N:N:N78	N:N:Y79	15.12	No	Yes	9	8	8
183	N:N:V82	N:N:Y79	3.79	No	Yes	0	4	8
184	N:N:A105	N:N:Y79	2.67	No	Yes	9	9	8
185	N:N:Q109	N:N:R80	8.18	No	No	0	3	4
186	N:N:A103	N:N:V82	5.09	No	No	0	9	4
187	N:N:E85	N:N:R83	5.82	No	No	0	6	4
188	N:N:R83	N:N:V104	3.92	No	No	0	4	9
189	N:N:F84	N:N:S101	3.96	No	No	0	8	6
190	N:N:E85	N:N:Y102	15.71	No	No	0	6	6
191	N:N:I87	N:N:V100	4.61	No	No	0	4	6
192	N:N:I87	N:N:Y102	8.46	No	No	0	4	6
193	N:N:C92	N:N:L89	7.94	Yes	Yes	10	9	8
194	N:N:L89	N:N:P98	4.93	Yes	No	10	8	9
195	N:N:L89	N:N:V100	8.94	Yes	No	0	8	6
196	N:N:C92	N:N:P93	1.88	Yes	No	10	9	5
197	N:N:C92	N:N:P98	1.88	Yes	No	10	9	9
198	N:N:G95	N:N:V96	1.84	No	No	0	5	7
199	N:N:N97	N:N:P98	8.15	No	No	0	8	9
200	N:N:N97	N:N:V99	10.35	No	No	0	8	3
201	N:N:C113	N:N:C120	7.28	No	No	0	9	9
202	N:N:R114	N:N:T117	15.52	No	No	0	5	6
203	N:N:D119	N:N:R115	9.53	Yes	Yes	2	9	7
204	N:N:R115	R:R:C131	5.57	Yes	Yes	2	7	7
205	N:N:R115	R:R:C156	5.57	Yes	No	2	7	7
206	N:N:R115	R:R:E206	2.33	Yes	Yes	0	7	4
207	N:N:S116	R:R:E206	4.31	No	Yes	0	6	4
208	N:N:T117	N:N:T118	6.28	No	No	0	6	8
209	N:N:C120	N:N:T118	3.38	No	No	0	9	8
210	N:N:D119	R:R:Q106	2.61	Yes	Yes	2	9	7
211	N:N:D119	R:R:N107	6.73	Yes	Yes	2	9	7
212	N:N:G121	N:N:G122	2.11	No	No	0	7	4
213	N:N:G122	N:N:P123	4.06	No	Yes	0	4	4
214	N:N:P123	R:R:R53	2.88	Yes	No	0	4	2
215	N:N:H126	N:N:K124	5.24	Yes	Yes	2	3	7
216	N:N:K124	R:R:S55	3.06	Yes	No	0	7	4
217	N:N:K124	R:R:A57	6.42	Yes	No	0	7	4
218	N:N:K124	R:R:S81	3.06	Yes	Yes	2	7	6
219	N:N:K124	R:R:Q82	6.78	Yes	Yes	2	7	6
220	N:N:H126	R:R:Y58	5.44	Yes	Yes	2	3	5
221	N:N:D131	R:R:E32	11.69	No	No	0	5	3
222	R:R:E32	R:R:P33	7.86	No	No	0	3	4
223	R:R:C34	R:R:C36	1.82	No	No	0	8	8
224	R:R:C36	R:R:P38	1.88	No	No	0	8	3
225	R:R:C36	R:R:L59	3.17	No	Yes	0	8	7
226	R:R:P38	R:R:V37	5.3	No	No	0	3	2
227	R:R:L51	R:R:V37	4.47	No	No	0	5	2
228	R:R:G46	R:R:P38	2.03	No	No	0	3	3
229	R:R:G40	R:R:V61	1.84	No	No	0	5	6
230	R:R:A41	R:R:L42	3.15	No	No	0	5	3
231	R:R:K62	R:R:R43	12.38	No	No	0	4	6
232	R:R:C44	R:R:P45	1.88	No	Yes	0	5	5
233	R:R:P45	R:R:P47	9.74	Yes	Yes	0	5	1
234	R:R:P45	R:R:V61	15.91	Yes	No	0	5	6
235	R:R:I64	R:R:P45	8.47	No	Yes	4	7	5
236	R:R:P45	R:R:P65	5.84	Yes	No	4	5	6
237	R:R:G46	R:R:P47	4.06	No	Yes	0	3	1
238	R:R:A68	R:R:P47	5.61	No	Yes	0	8	1
239	R:R:F69	R:R:P47	5.78	Yes	Yes	0	8	1
240	R:R:E74	R:R:G50	6.55	No	No	0	4	3
241	R:R:K77	R:R:R53	3.71	Yes	No	0	5	2
242	R:R:E79	R:R:R53	30.24	No	No	0	5	2
243	R:R:F69	R:R:L54	8.53	Yes	No	0	8	7
244	R:R:E79	R:R:S55	4.31	No	No	0	5	4
245	R:R:L56	R:R:L59	6.92	No	Yes	0	6	7
246	R:R:I80	R:R:L56	5.71	Yes	No	0	8	6
247	R:R:Q82	R:R:Y58	6.76	Yes	Yes	2	6	5
248	R:R:L59	R:R:P60	3.28	Yes	No	0	7	5
249	R:R:L59	R:R:V61	4.47	Yes	No	0	7	6
250	R:R:P60	R:R:S85	1.78	No	No	0	5	5
251	R:R:E87	R:R:K62	8.1	No	No	0	5	4
252	R:R:I64	R:R:P65	5.08	No	No	4	7	6
253	R:R:I64	R:R:I89	4.42	No	No	4	7	8
254	R:R:A68	R:R:P65	5.61	No	No	0	8	6
255	R:R:E90	R:R:S66	8.62	No	No	0	6	4
256	R:R:Q67	R:R:R70	22.2	No	No	0	3	2
257	R:R:N92	R:R:Q67	2.64	No	No	0	6	3
258	R:R:F69	R:R:I78	7.54	Yes	Yes	1	8	8
259	R:R:F69	R:R:F94	16.08	Yes	Yes	1	8	9
260	R:R:N73	R:R:N99	6.81	No	No	0	4	5
261	R:R:I76	R:R:K77	5.82	No	Yes	0	3	5
262	R:R:E102	R:R:K77	16.2	Yes	Yes	19	7	5
263	R:R:F94	R:R:I78	13.82	Yes	Yes	1	9	8
264	R:R:I78	R:R:L100	8.56	Yes	No	1	8	9
265	R:R:I103	R:R:I78	5.89	Yes	Yes	1	8	8
266	R:R:I80	R:R:I83	4.42	Yes	No	22	8	7
267	R:R:I80	R:R:L86	4.28	Yes	No	22	8	8
268	R:R:I105	R:R:I80	4.42	No	Yes	0	8	8
269	R:R:Q82	R:R:S81	4.33	Yes	Yes	2	6	6
270	R:R:Q106	R:R:S81	5.78	Yes	Yes	2	7	6
271	R:R:N107	R:R:S81	4.47	Yes	Yes	2	7	6
272	R:R:N107	R:R:Q82	6.6	Yes	Yes	2	7	6
273	R:R:I83	R:R:L86	15.7	No	No	22	7	8
274	R:R:D84	R:R:S85	7.36	No	No	0	7	5
275	R:R:E87	R:R:R88	9.3	No	No	0	5	1
276	R:R:E87	R:R:N110	5.26	No	No	0	5	5
277	R:R:E90	R:R:R88	3.49	No	No	0	6	1
278	R:R:R88	R:R:Y113	2.06	No	Yes	0	1	1
279	R:R:I89	R:R:L111	4.28	No	Yes	4	8	7
280	R:R:I114	R:R:I89	2.94	Yes	No	4	8	8
281	R:R:E115	R:R:E90	7.61	No	No	0	5	6
282	R:R:A91	R:R:E115	7.54	No	No	0	5	5
283	R:R:D95	R:R:N92	10.77	Yes	No	12	6	6
284	R:R:I120	R:R:N92	2.83	Yes	No	12	5	6
285	R:R:A93	R:R:F94	2.77	No	Yes	0	8	9
286	R:R:F94	R:R:L97	9.74	Yes	No	0	9	8
287	R:R:F94	R:R:I103	6.28	Yes	Yes	1	9	8
288	R:R:F119	R:R:F94	8.57	Yes	Yes	1	8	9
289	R:R:D95	R:R:N96	4.04	Yes	No	12	6	5
290	R:R:D95	R:R:I120	2.8	Yes	Yes	12	6	5
291	R:R:D95	R:R:N121	5.39	Yes	No	12	6	7
292	R:R:N121	R:R:N96	5.45	No	No	12	7	5
293	R:R:L100	R:R:L97	5.54	No	No	0	9	8
294	R:R:L98	R:R:R124	2.43	No	No	0	6	6
295	R:R:I103	R:R:L100	7.14	Yes	No	1	8	9
296	R:R:K126	R:R:S101	6.12	Yes	No	0	5	5
297	R:R:E102	R:R:L104	14.58	Yes	No	0	7	5
298	R:R:E102	R:R:Y127	7.86	Yes	Yes	0	7	6
299	R:R:F119	R:R:I103	2.51	Yes	Yes	1	8	8
300	R:R:I103	R:R:L128	2.85	Yes	Yes	1	8	8
301	R:R:L104	R:R:Q106	3.99	No	Yes	0	5	7
302	R:R:I105	R:R:I130	10.3	No	No	0	8	8
303	R:R:N107	R:R:Q106	3.96	Yes	Yes	2	7	7
304	R:R:C131	R:R:Q106	4.58	Yes	Yes	2	7	7
305	R:R:L111	R:R:T108	14.74	Yes	No	4	7	8
306	R:R:T108	R:R:T133	9.42	No	Yes	4	8	8
307	R:R:G134	R:R:T108	1.82	No	No	4	5	8
308	R:R:I114	R:R:L111	4.28	Yes	Yes	4	8	7
309	R:R:L111	R:R:T133	5.9	Yes	Yes	4	7	8
310	R:R:I135	R:R:Y113	4.84	Yes	Yes	4	7	1
311	R:R:R136	R:R:Y113	4.12	No	Yes	0	3	1
312	R:R:K137	R:R:Y113	15.53	No	Yes	4	3	1
313	R:R:I114	R:R:I135	13.25	Yes	Yes	4	8	7
314	R:R:I114	R:R:P139	8.47	Yes	No	0	8	9
315	R:R:E115	R:R:P116	9.43	No	No	0	5	4
316	R:R:G117	R:R:K143	5.23	No	No	0	3	4
317	R:R:A118	R:R:F119	2.77	No	Yes	0	7	8
318	R:R:F119	R:R:L122	2.44	Yes	Yes	1	8	8
319	R:R:F119	R:R:L128	9.74	Yes	Yes	1	8	8
320	R:R:I120	R:R:K143	7.27	Yes	No	0	5	4
321	R:R:N121	R:R:P123	3.26	No	No	0	7	4
322	R:R:L122	R:R:L125	12.46	Yes	Yes	1	8	9
323	R:R:L122	R:R:V144	4.47	Yes	No	1	8	7
324	R:R:P123	R:R:S147	1.78	No	No	0	4	5
325	R:R:E148	R:R:R124	4.65	No	No	0	5	6
326	R:R:L125	R:R:V144	5.96	Yes	No	1	9	7
327	R:R:L125	R:R:S146	3	Yes	No	0	9	7
328	R:R:F151	R:R:L125	8.53	Yes	Yes	1	5	9
329	R:R:K126	R:R:Y127	21.5	Yes	Yes	0	5	6
330	R:R:E148	R:R:K126	9.45	No	Yes	0	5	5
331	R:R:I152	R:R:Y127	2.42	No	Yes	0	4	6
332	R:R:F151	R:R:L128	2.44	Yes	Yes	1	5	8
333	R:R:L128	R:R:L153	4.15	Yes	No	1	8	9
334	R:R:E154	R:R:S129	2.87	No	No	0	7	7
335	R:R:I130	R:R:T133	9.12	No	Yes	0	8	8
336	R:R:I130	R:R:I155	4.42	No	Yes	0	8	8
337	R:R:C131	R:R:C156	3.64	Yes	No	2	7	7
338	R:R:D157	R:R:N132	6.73	Yes	No	15	6	8
339	R:R:G134	R:R:T133	1.82	No	Yes	4	5	8
340	R:R:I135	R:R:T133	4.56	Yes	Yes	4	7	8
341	R:R:G134	R:R:H160	9.53	No	No	0	5	3
342	R:R:I135	R:R:K137	4.36	Yes	No	4	7	3
343	R:R:F138	R:R:P139	5.78	Yes	No	0	5	9
344	R:R:F138	R:R:I155	2.51	Yes	Yes	1	5	8
345	R:R:F138	R:R:I161	6.28	Yes	No	0	5	7
346	R:R:F138	R:R:I164	13.82	Yes	Yes	1	5	7
347	R:R:F138	R:R:P165	10.11	Yes	No	1	5	7
348	R:R:F138	R:R:N184	3.62	Yes	Yes	1	5	9
349	R:R:D140	R:R:T142	8.67	No	No	0	3	4
350	R:R:D140	R:R:K143	6.91	No	No	0	3	4
351	R:R:F169	R:R:V141	2.62	Yes	No	1	6	5
352	R:R:M172	R:R:V141	3.04	Yes	No	1	6	5
353	R:R:M172	R:R:V144	3.04	Yes	No	1	6	7
354	R:R:E175	R:R:S149	5.75	No	No	0	5	3
355	R:R:I152	R:R:N150	9.91	No	No	0	4	5
356	R:R:N150	R:R:T178	5.85	No	No	0	5	6
357	R:R:F151	R:R:L153	2.44	Yes	No	1	5	9
358	R:R:F151	R:R:M172	6.22	Yes	Yes	1	5	6
359	R:R:F151	R:R:N173	3.62	Yes	No	1	5	4
360	R:R:F151	R:R:V177	5.24	Yes	Yes	1	5	3
361	R:R:I155	R:R:L153	2.85	Yes	No	1	8	9
362	R:R:E154	R:R:K180	10.8	No	Yes	0	7	5
363	R:R:I155	R:R:N158	8.5	Yes	No	1	8	9
364	R:R:I155	R:R:L181	4.28	Yes	Yes	1	8	8
365	R:R:I155	R:R:N184	9.91	Yes	Yes	1	8	9
366	R:R:D157	R:R:L159	6.79	Yes	No	0	6	3
367	R:R:I161	R:R:N158	12.74	No	No	0	7	9
368	R:R:N158	R:R:N184	4.09	No	Yes	1	9	9
369	R:R:E187	R:R:T162	7.06	No	No	0	2	3
370	R:R:Q190	R:R:T163	8.5	No	No	0	2	3
371	R:R:I164	R:R:P165	5.08	Yes	No	1	7	7
372	R:R:A168	R:R:I164	3.25	No	Yes	1	7	7
373	R:R:I164	R:R:V189	4.61	Yes	No	0	7	7
374	R:R:A168	R:R:P165	1.87	No	No	1	7	7
375	R:R:G166	R:R:Q190	3.29	No	No	0	4	2
376	R:R:N167	R:R:Q170	18.49	No	No	0	7	3
377	R:R:H192	R:R:N167	3.83	No	No	0	5	7
378	R:R:A168	R:R:F169	2.77	No	Yes	1	7	6
379	R:R:F169	R:R:M172	3.73	Yes	Yes	1	6	6
380	R:R:F169	R:R:L179	14.61	Yes	Yes	1	6	8
381	R:R:N195	R:R:Q170	7.92	No	No	0	5	3
382	R:R:M172	R:R:V177	6.09	Yes	Yes	1	6	3
383	R:R:E175	R:R:N173	3.94	No	No	0	5	4
384	R:R:N173	R:R:V177	2.96	No	Yes	1	4	3
385	R:R:E175	R:R:N174	5.26	No	No	0	5	4
386	R:R:S176	R:R:T198	6.4	No	No	0	5	5
387	R:R:S176	R:R:T200	3.2	No	No	0	5	4
388	R:R:L179	R:R:V177	4.47	Yes	Yes	1	8	3
389	R:R:T197	R:R:V177	3.17	No	Yes	0	5	3
390	R:R:T178	R:R:T200	9.42	No	No	3	6	4
391	R:R:S201	R:R:T178	3.2	Yes	No	3	5	6
392	R:R:L179	R:R:L181	2.77	Yes	Yes	1	8	8
393	R:R:L179	R:R:L199	4.15	Yes	Yes	1	8	8
394	R:R:L179	R:R:L202	4.15	Yes	No	1	8	7
395	R:R:K180	R:R:Y182	16.72	Yes	Yes	3	5	6
396	R:R:E203	R:R:K180	13.5	Yes	Yes	3	5	5
397	R:R:L181	R:R:N184	8.24	Yes	Yes	1	8	9
398	R:R:L181	R:R:L204	4.15	Yes	No	0	8	9
399	R:R:E203	R:R:Y182	12.35	Yes	Yes	3	5	6
400	R:R:K205	R:R:Y182	5.97	Yes	Yes	3	7	6
401	R:R:D228	R:R:Y182	12.64	Yes	Yes	3	9	6
402	R:R:E206	R:R:G183	3.27	Yes	No	0	4	7
403	R:R:F186	R:R:N184	9.67	Yes	Yes	1	8	9
404	R:R:N184	R:R:N207	4.09	Yes	Yes	1	9	9
405	R:R:F186	R:R:V189	3.93	Yes	No	0	8	7
406	R:R:F186	R:R:N207	15.71	Yes	Yes	1	8	9
407	R:R:F186	R:R:L210	15.83	Yes	Yes	1	8	8
408	R:R:E188	R:R:K212	6.75	No	No	0	5	2
409	R:R:E188	R:R:H214	8.62	No	No	0	5	5
410	R:R:M213	R:R:V189	3.04	Yes	No	0	6	7
411	R:R:H214	R:R:S191	4.18	No	No	0	5	5
412	R:R:A193	R:R:F194	5.55	No	Yes	0	8	9
413	R:R:F194	R:R:L199	7.31	Yes	Yes	1	9	8
414	R:R:A217	R:R:F194	2.77	No	Yes	0	7	9
415	R:R:A221	R:R:F194	2.77	No	Yes	1	8	9
416	R:R:G196	R:R:N195	5.09	No	No	0	6	5
417	R:R:G220	R:R:N195	3.39	No	No	0	5	5
418	R:R:G196	R:R:T197	1.82	No	No	0	6	5
419	R:R:L199	R:R:T197	2.95	Yes	No	0	8	5
420	R:R:T198	R:R:T222	3.14	No	No	0	5	3
421	R:R:L199	R:R:L202	6.92	Yes	No	1	8	7
422	R:R:A221	R:R:L199	3.15	No	Yes	1	8	8
423	R:R:S201	R:R:T200	3.2	Yes	No	3	5	4
424	R:R:E203	R:R:S201	5.75	Yes	Yes	3	5	5
425	R:R:S201	R:R:T226	3.2	Yes	No	0	5	4
426	R:R:L202	R:R:P224	13.14	No	No	0	7	8
427	R:R:D228	R:R:E203	5.2	Yes	Yes	3	9	5
428	R:R:L204	R:R:N207	4.12	No	Yes	0	9	9
429	R:R:E206	R:R:K205	5.4	Yes	Yes	0	4	7
430	R:R:D228	R:R:K205	9.68	Yes	Yes	3	9	7
431	R:R:K205	R:R:S230	9.18	Yes	Yes	3	7	9
432	R:R:K205	R:R:S231	4.59	Yes	No	0	7	6
433	R:R:L210	R:R:N207	15.1	Yes	Yes	1	8	9
434	R:R:N207	R:R:T232	4.39	Yes	No	1	9	9
435	R:R:H209	R:R:V208	6.92	No	No	0	1	1
436	R:R:K233	R:R:V208	4.55	No	No	0	3	1
437	R:R:L210	R:R:M213	2.83	Yes	Yes	0	8	6
438	R:R:L210	R:R:T232	2.95	Yes	No	1	8	9
439	R:R:E211	R:R:K212	2.7	No	No	0	2	2
440	R:R:L234	R:R:M213	7.07	No	Yes	0	7	6
441	R:R:M213	R:R:P238	3.35	Yes	No	0	6	9
442	R:R:G216	R:R:N215	3.39	No	No	0	3	1
443	R:R:G216	R:R:R219	4.5	No	No	0	3	1
444	R:R:F218	R:R:Y240	5.16	No	No	0	8	2
445	R:R:F218	R:R:G241	9.03	No	No	23	8	7
446	R:R:E243	R:R:F218	7	No	No	23	3	8
447	R:R:G223	R:R:P224	4.06	No	No	0	7	8
448	R:R:G223	R:R:S244	1.86	No	No	0	7	4
449	R:R:K225	R:R:Q246	4.07	No	No	0	3	6
450	R:R:R247	R:R:T226	6.47	Yes	No	0	5	4
451	R:R:I229	R:R:L227	2.85	No	No	0	7	8
452	R:R:L227	R:R:L248	4.15	No	No	0	8	9
453	R:R:D228	R:R:S230	5.89	Yes	Yes	3	9	9
454	R:R:D228	R:R:I249	15.39	Yes	No	3	9	5
455	R:R:I229	R:R:T232	12.16	No	No	0	7	9
456	R:R:I229	R:R:L234	2.85	No	No	0	7	7
457	R:R:I249	R:R:S230	7.74	No	Yes	3	5	9
458	R:R:S230	R:R:T251	6.4	Yes	Yes	3	9	4
459	R:R:K233	R:R:S255	4.59	No	No	0	3	4
460	R:R:L234	R:R:L237	2.77	No	No	0	7	7
461	R:R:Q235	R:R:S255	2.89	No	No	0	4	4
462	R:R:A236	R:R:K258	3.21	No	No	0	5	5
463	R:R:L237	R:R:P238	3.28	No	No	0	7	9
464	R:R:L237	R:R:L256	4.15	No	No	0	7	8
465	R:R:E243	R:R:G241	4.91	No	No	23	3	7
466	R:R:I245	R:R:L242	2.85	No	Yes	0	8	9
467	R:R:L242	R:R:P260	3.28	Yes	No	16	9	6
468	R:R:L242	R:R:T264	4.42	Yes	No	16	9	4
469	R:R:F265	R:R:L242	9.74	Yes	Yes	16	7	9
470	R:R:E243	R:R:S244	5.75	No	No	0	3	4
471	R:R:I245	R:R:L248	5.71	No	No	0	8	9
472	R:R:Q246	R:R:R247	3.5	No	Yes	0	6	5
473	R:R:L269	R:R:Q246	9.32	No	No	0	4	6
474	R:R:E270	R:R:R247	8.14	No	Yes	0	6	5
475	R:R:F265	R:R:L248	3.65	Yes	No	0	7	9
476	R:R:I249	R:R:T251	4.56	No	Yes	3	5	4
477	R:R:A250	R:R:S253	3.42	No	No	0	8	7
478	R:R:S252	R:R:T251	3.2	No	Yes	0	7	4
479	R:R:L256	R:R:S253	6.01	No	No	0	8	7
480	R:R:K257	R:R:Y254	3.58	No	No	0	7	2
481	R:R:I431	R:R:K257	8.72	Yes	No	0	8	7
482	R:R:L259	R:R:P260	4.93	No	No	0	6	6
483	R:R:H278	R:R:L259	14.14	No	No	0	9	6
484	R:R:L259	R:R:N428	4.12	No	Yes	0	6	6
485	R:R:F265	R:R:P260	10.11	Yes	No	16	7	6
486	R:R:S261	R:R:T264	4.8	No	No	0	4	4
487	R:R:F282	R:R:R262	4.28	Yes	No	0	8	5
488	R:R:P286	R:R:R262	2.88	No	No	0	4	5
489	R:R:P341	R:R:R262	5.76	No	No	0	6	5
490	R:R:E263	R:R:P286	4.72	No	No	0	4	4
491	R:R:F265	R:R:T264	5.19	Yes	No	16	7	4
492	R:R:F265	R:R:L268	8.53	Yes	No	0	7	6
493	R:R:N267	R:R:V266	2.96	No	No	0	4	4
494	R:R:A271	R:R:L268	3.15	No	No	0	7	6
495	R:R:F282	R:R:L268	4.87	Yes	No	0	8	6
496	R:R:L269	R:R:L337	8.3	No	No	24	4	3
497	R:R:L269	R:R:P338	8.21	No	No	24	4	3
498	R:R:H278	R:R:L273	16.71	No	Yes	0	9	7
499	R:R:C279	R:R:L273	3.17	No	Yes	26	9	7
500	R:R:C343	R:R:L273	4.76	No	Yes	26	9	7
501	R:R:P276	R:R:Y275	5.56	No	No	0	7	8
502	R:R:S277	R:R:Y275	15.26	No	No	0	8	8
503	R:R:I431	R:R:Y275	7.25	Yes	No	0	8	8
504	R:R:D348	R:R:P276	3.22	No	No	0	9	7
505	R:R:F282	R:R:H278	6.79	Yes	No	0	8	9
506	R:R:C279	R:R:C343	3.64	No	No	26	9	9
507	R:R:C279	R:R:P347	3.77	No	No	0	9	8
508	R:R:C280	R:R:P347	7.53	No	No	0	9	8
509	R:R:C280	R:R:C353	7.28	No	No	0	9	9
510	R:R:A281	R:R:F282	2.77	No	Yes	0	8	8
511	R:R:C343	R:R:F282	4.19	No	Yes	0	9	8
512	R:R:R283	R:R:T340	5.17	No	Yes	0	3	4
513	R:R:L285	R:R:T340	5.9	No	Yes	0	4	4
514	R:R:D330	R:R:Y331	5.75	No	No	0	4	1
515	R:R:C336	R:R:Y333	6.72	No	No	0	6	1
516	R:R:L337	R:R:P338	3.28	No	No	24	3	3
517	R:R:K339	R:R:T340	7.51	No	Yes	0	3	4
518	R:R:P341	R:R:T340	6.99	No	Yes	0	6	4
519	R:R:A344	R:R:P345	1.87	No	No	0	6	9
520	R:R:E346	R:R:P347	3.14	No	No	0	4	8
521	R:R:D348	R:R:N351	2.69	No	No	0	9	8
522	R:R:F350	R:R:M517	7.46	No	No	0	8	8
523	R:R:E520	R:R:F350	3.5	No	No	0	5	8
524	R:R:N351	R:R:Q434	3.96	No	No	0	8	9
525	R:R:P352	R:R:V601	10.6	No	No	0	9	8
526	R:R:P352	R:R:T602	3.5	No	No	0	9	7
527	R:R:D355	R:R:I356	2.8	Yes	Yes	8	7	8
528	R:R:D355	R:R:D419	9.31	Yes	No	8	7	9
529	R:R:D355	R:R:T422	4.34	Yes	No	0	7	9
530	R:R:D355	R:R:Y426	12.64	Yes	No	0	7	9
531	R:R:I356	R:R:M357	7.29	Yes	Yes	8	8	7
532	R:R:D419	R:R:I356	9.8	No	Yes	8	9	8
533	R:R:I356	R:R:I513	2.94	Yes	No	0	8	9
534	R:R:L362	R:R:M357	5.65	Yes	Yes	8	8	7
535	R:R:I366	R:R:M357	4.37	No	Yes	8	9	7
536	R:R:D419	R:R:M357	4.16	No	Yes	8	9	7
537	R:R:M357	R:R:V609	3.04	Yes	No	8	7	9
538	R:R:G358	R:R:Y359	2.9	No	Yes	0	8	6
539	R:R:F361	R:R:Y359	12.38	No	Yes	8	5	6
540	R:R:L362	R:R:Y359	7.03	Yes	Yes	8	8	6
541	R:R:T602	R:R:Y359	2.5	No	Yes	0	7	6
542	R:R:V606	R:R:Y359	5.05	No	Yes	0	7	6
543	R:R:D360	R:R:F361	4.78	No	No	0	4	5
544	R:R:F361	R:R:L362	6.09	No	Yes	8	5	8
545	R:R:L362	R:R:V609	4.47	Yes	No	8	8	9
546	R:R:R363	R:R:W367	11	No	No	0	9	9
547	R:R:I369	R:R:L365	4.28	No	No	0	8	6
548	R:R:I366	R:R:L412	2.85	No	No	0	9	8
549	R:R:I366	R:R:V609	4.61	No	No	8	9	9
550	R:R:L413	R:R:W367	2.28	No	No	0	6	9
551	R:R:A416	R:R:W367	3.89	No	No	0	9	9
552	R:R:I371	R:R:L368	2.85	No	No	0	4	4
553	R:R:I369	R:R:P613	5.08	No	No	0	8	9
554	R:R:I371	R:R:N370	2.83	No	No	0	4	6
555	R:R:I374	R:R:N370	4.25	No	No	0	5	6
556	R:R:L413	R:R:N370	10.98	No	No	0	6	6
557	R:R:I371	R:R:M375	2.92	No	No	0	4	2
558	R:R:F621	R:R:L372	4.87	No	No	0	8	5
559	R:R:A373	R:R:C617	1.81	No	No	0	9	9
560	R:R:I374	R:R:M378	5.83	No	No	0	5	3
561	R:R:F406	R:R:I374	3.77	No	No	0	4	5
562	R:R:G376	R:R:T379	1.82	No	No	0	7	4
563	R:R:N377	R:R:S402	5.96	Yes	No	0	9	8
564	R:R:D405	R:R:N377	4.04	Yes	Yes	0	9	9
565	R:R:F406	R:R:N377	7.25	No	Yes	0	4	9
566	R:R:F382	R:R:M378	4.98	No	No	0	1	3
567	R:R:S402	R:R:V380	4.85	No	No	0	8	9
568	R:R:A624	R:R:V380	3.39	Yes	No	13	7	9
569	R:R:F630	R:R:V380	5.24	Yes	No	13	8	9
570	R:R:L384	R:R:V383	2.98	Yes	No	13	6	7
571	R:R:F630	R:R:V383	17.04	Yes	No	13	8	7
572	R:R:D633	R:R:V383	4.38	No	No	0	8	7
573	R:R:L384	R:R:R395	3.64	Yes	Yes	0	6	7
574	R:R:C399	R:R:L384	4.76	No	Yes	0	8	6
575	R:R:F630	R:R:L384	4.87	Yes	Yes	13	8	6
576	R:R:L637	R:R:T386	7.37	No	No	0	7	5
577	R:R:R395	R:R:S387	2.64	Yes	No	0	7	7
578	R:R:D633	R:R:S387	8.83	No	No	0	8	7
579	R:R:R395	R:R:Y389	4.12	Yes	No	0	7	3
580	R:R:L636	R:R:Y389	4.69	No	No	0	3	3
581	R:R:P394	R:R:T392	12.24	No	No	0	6	8
582	R:R:R395	R:R:T392	6.47	Yes	No	0	7	8
583	R:R:P394	R:R:V393	5.3	No	No	0	6	8
584	R:R:L480	R:R:V393	4.47	No	No	0	3	8
585	R:R:R395	R:R:T629	2.59	Yes	No	0	7	6
586	R:R:F396	R:R:N400	3.62	No	No	0	7	7
587	R:R:F396	R:R:I484	3.77	No	No	0	7	3
588	R:R:I460	R:R:L397	7.14	Yes	No	17	9	7
589	R:R:E463	R:R:L397	3.98	No	No	17	9	7
590	R:R:M398	R:R:Y623	5.99	No	Yes	0	7	9
591	R:R:A624	R:R:M398	3.22	Yes	No	0	7	7
592	R:R:M487	R:R:N400	7.01	No	No	0	7	7
593	R:R:N400	R:R:W491	4.52	No	Yes	0	7	5
594	R:R:D405	R:R:L401	5.43	Yes	No	0	9	8
595	R:R:L401	R:R:T456	4.42	No	No	0	8	8
596	R:R:L401	R:R:N619	8.24	No	No	0	8	9
597	R:R:C407	R:R:F403	8.38	No	No	0	7	5
598	R:R:F403	R:R:W491	5.01	No	Yes	0	5	5
599	R:R:A404	R:R:L452	4.73	No	No	0	8	7
600	R:R:D405	R:R:S616	2.94	Yes	No	0	9	9
601	R:R:D405	R:R:P620	4.83	Yes	No	0	9	9
602	R:R:C407	R:R:L410	3.17	No	Yes	0	7	4
603	R:R:A449	R:R:C407	1.81	No	No	0	8	7
604	R:R:M408	R:R:Y411	4.79	Yes	Yes	11	8	7
605	R:R:A449	R:R:M408	3.22	No	Yes	0	8	8
606	R:R:M408	R:R:S450	3.07	Yes	No	11	8	8
607	R:R:M408	R:R:Y612	3.59	Yes	No	11	8	7
608	R:R:M408	R:R:S616	7.67	Yes	No	0	8	9
609	R:R:L410	R:R:Y411	2.34	Yes	Yes	11	4	7
610	R:R:F445	R:R:L410	2.44	Yes	Yes	11	7	4
611	R:R:L412	R:R:Y411	10.55	No	Yes	0	8	7
612	R:R:I415	R:R:Y411	7.25	No	Yes	0	8	7
613	R:R:F445	R:R:Y411	2.06	Yes	Yes	11	7	7
614	R:R:T446	R:R:Y411	16.23	No	Yes	0	8	7
615	R:R:Y411	R:R:Y612	6.95	Yes	No	11	7	7
616	R:R:V418	R:R:W433	20.84	No	No	0	7	9
617	R:R:H429	R:R:T422	9.58	No	No	0	6	9
618	R:R:N428	R:R:Q425	2.64	Yes	No	25	6	4
619	R:R:H429	R:R:Q425	6.18	No	No	25	6	4
620	R:R:A430	R:R:Y426	6.67	No	No	0	9	9
621	R:R:S512	R:R:Y426	5.09	No	No	0	9	9
622	R:R:H429	R:R:N428	17.86	No	Yes	25	6	6
623	R:R:I431	R:R:T435	3.04	Yes	No	0	8	6
624	R:R:D432	R:R:W433	2.23	No	No	0	4	9
625	R:R:G438	R:R:W433	4.22	No	No	0	8	9
626	R:R:M509	R:R:Q434	8.16	No	No	0	6	9
627	R:R:Q434	R:R:S512	4.33	No	No	0	9	9
628	R:R:M509	R:R:T435	4.52	No	No	0	6	6
629	R:R:C439	R:R:Y508	8.06	No	No	14	9	8
630	R:R:C439	R:R:C514	7.28	No	Yes	14	9	9
631	R:R:F445	R:R:T441	7.78	Yes	No	0	7	3
632	R:R:A442	R:R:G443	1.95	No	Yes	14	8	9
633	R:R:A442	R:R:C514	3.61	No	Yes	14	8	9
634	R:R:G443	R:R:T446	5.46	Yes	No	0	9	8
635	R:R:G443	R:R:Y508	7.24	Yes	No	14	9	8
636	R:R:C514	R:R:G443	1.96	Yes	Yes	14	9	9
637	R:R:F444	R:R:F445	2.14	Yes	Yes	0	8	7
638	R:R:A498	R:R:F444	5.55	No	Yes	0	9	8
639	R:R:F444	R:R:M499	7.46	Yes	No	0	8	3
640	R:R:F444	R:R:L502	6.09	Yes	No	0	8	7
641	R:R:E451	R:R:V447	4.28	No	No	0	9	8
642	R:R:A498	R:R:V447	3.39	No	No	0	9	8
643	R:R:F448	R:R:W491	10.02	Yes	Yes	27	8	5
644	R:R:F448	R:R:S494	5.28	Yes	No	0	8	7
645	R:R:F448	R:R:S495	5.28	Yes	No	27	8	3
646	R:R:A498	R:R:F448	4.16	No	Yes	0	9	8
647	R:R:S450	R:R:Y612	7.63	No	No	11	8	7
648	R:R:E451	R:R:S494	2.87	No	No	0	9	7
649	R:R:E451	R:R:I497	4.1	No	Yes	0	9	5
650	R:R:L452	R:R:T456	2.95	No	No	0	7	8
651	R:R:L452	R:R:W491	10.25	No	Yes	0	7	5
652	R:R:N535	R:R:V454	4.43	No	No	0	9	7
653	R:R:I486	R:R:Y455	3.63	No	No	0	5	8
654	R:R:M487	R:R:Y455	2.39	No	No	0	7	8
655	R:R:G490	R:R:Y455	7.24	No	No	0	8	8
656	R:R:I460	R:R:T456	3.04	Yes	No	0	9	8
657	R:R:I542	R:R:T458	6.08	No	No	0	8	8
658	R:R:E463	R:R:I460	2.73	No	Yes	17	9	9
659	R:R:I460	R:R:R464	5.01	Yes	No	17	9	8
660	R:R:I542	R:R:T461	15.2	No	Yes	29	8	8
661	R:R:C545	R:R:T461	3.38	Yes	Yes	0	6	8
662	R:R:T461	R:R:Y546	8.74	Yes	Yes	29	8	9
663	R:R:E463	R:R:R464	8.14	No	No	17	9	8
664	R:R:R464	R:R:Y623	3.09	No	Yes	0	8	9
665	R:R:H466	R:R:W465	2.12	Yes	Yes	0	5	5
666	R:R:T469	R:R:W465	7.28	No	Yes	0	5	5
667	R:R:C545	R:R:W465	6.53	Yes	Yes	0	6	5
668	R:R:K548	R:R:W465	3.48	No	Yes	0	4	5
669	R:R:I549	R:R:W465	7.05	No	Yes	0	9	5
670	R:R:H466	R:R:Y470	5.44	Yes	No	30	5	3
671	R:R:H466	R:R:Q476	2.47	Yes	No	30	5	5
672	R:R:H466	R:R:L478	3.86	Yes	No	0	5	4
673	R:R:T469	R:R:Y470	7.49	No	No	0	5	3
674	R:R:Q476	R:R:Y470	4.51	No	No	30	5	3
675	R:R:H473	R:R:I472	10.61	No	No	0	4	5
676	R:R:K477	R:R:L474	2.82	No	No	0	5	3
677	R:R:D475	R:R:Q476	9.14	No	No	0	4	5
678	R:R:H482	R:R:L478	2.57	No	No	0	5	4
679	R:R:I484	R:R:L488	4.28	No	No	0	3	1
680	R:R:G489	R:R:G490	2.11	No	No	0	3	8
681	R:R:S495	R:R:W491	2.47	No	Yes	27	3	5
682	R:R:L492	R:R:L496	5.54	No	No	0	1	3
683	R:R:F493	R:R:I497	10.05	No	Yes	0	5	5
684	R:R:F493	R:R:L534	2.44	No	No	0	5	5
685	R:R:I497	R:R:Y527	7.25	Yes	No	28	5	7
686	R:R:I497	R:R:I531	2.94	Yes	Yes	28	5	6
687	R:R:L500	R:R:P501	3.28	No	No	0	5	9
688	R:R:L500	R:R:V505	13.41	No	No	0	5	5
689	R:R:L500	R:R:Y527	8.21	No	No	0	5	7
690	R:R:P501	R:R:S506	1.78	No	Yes	0	9	8
691	R:R:G504	R:R:V503	1.84	No	No	0	6	4
692	R:R:S506	R:R:V505	3.23	Yes	No	0	8	5
693	R:R:L523	R:R:V505	2.98	No	No	0	4	5
694	R:R:P516	R:R:S506	1.78	No	Yes	0	9	8
695	R:R:S506	R:R:S524	4.89	Yes	No	0	8	7
696	R:R:M509	R:R:N507	2.8	No	No	0	6	7
697	R:R:C514	R:R:Y508	13.44	Yes	No	14	9	8
698	R:R:D518	R:R:K510	5.53	Yes	No	0	7	6
699	R:R:I513	R:R:V511	4.61	No	No	0	9	9
700	R:R:M517	R:R:V511	4.56	No	No	0	8	9
701	R:R:K605	R:R:S512	3.06	No	No	0	9	9
702	R:R:F515	R:R:P516	14.45	No	No	0	9	9
703	R:R:D518	R:R:E520	3.9	Yes	No	0	7	5
704	R:R:D518	R:R:T521	2.89	Yes	No	31	7	5
705	R:R:D518	R:R:S524	4.42	Yes	No	31	7	7
706	R:R:Q525	R:R:V519	5.73	No	No	0	6	6
707	R:R:S524	R:R:T521	7.99	No	No	31	7	5
708	R:R:I531	R:R:Y527	9.67	Yes	No	28	6	7
709	R:R:I528	R:R:L532	2.85	No	Yes	0	6	9
710	R:R:F594	R:R:L529	2.44	No	No	0	6	6
711	R:R:I531	R:R:L532	2.85	Yes	Yes	0	6	9
712	R:R:I531	R:R:N535	4.25	Yes	No	0	6	9
713	R:R:A589	R:R:L532	4.73	No	Yes	0	9	9
714	R:R:I590	R:R:L532	5.71	No	Yes	0	7	9
715	R:R:I541	R:R:V537	3.07	No	No	0	4	4
716	R:R:F539	R:R:I575	2.51	Yes	No	0	8	9
717	R:R:D578	R:R:F539	2.39	No	Yes	0	8	8
718	R:R:F539	R:R:F579	7.5	Yes	No	0	8	8
719	R:R:F539	R:R:M582	6.22	Yes	No	0	8	7
720	R:R:I542	R:R:Y546	2.42	No	Yes	29	8	9
721	R:R:C543	R:R:I575	3.27	No	No	0	7	9
722	R:R:A544	R:R:K548	3.21	No	No	0	3	4
723	R:R:M571	R:R:Y546	14.37	No	Yes	0	8	9
724	R:R:L574	R:R:Y546	9.38	No	Yes	0	9	9
725	R:R:F551	R:R:Y550	12.38	No	No	0	4	9
726	R:R:R554	R:R:Y550	23.66	No	No	0	5	9
727	R:R:D564	R:R:R554	10.72	No	No	0	8	5
728	R:R:L558	R:R:N555	2.75	No	No	0	4	7
729	R:R:E557	R:R:P556	3.14	No	No	0	4	6
730	R:R:D564	R:R:T565	2.89	No	No	0	8	6
731	R:R:K566	R:R:K570	8.62	No	Yes	0	5	9
732	R:R:A572	R:R:K569	3.21	No	No	0	9	7
733	R:R:I573	R:R:K569	5.82	No	No	0	5	7
734	R:R:I573	R:R:K570	2.91	No	Yes	0	5	9
735	R:R:K570	R:R:L574	14.1	Yes	No	0	9	9
736	R:R:K570	R:R:L622	2.82	Yes	No	0	9	9
737	R:R:L574	R:R:Y623	3.52	No	Yes	0	9	9
738	R:R:F576	R:R:I575	2.51	No	No	0	8	9
739	R:R:D578	R:R:N615	4.04	No	No	0	8	9
740	R:R:A583	R:R:F579	4.16	No	No	0	8	8
741	R:R:C581	R:R:I614	13.09	No	No	0	9	8
742	R:R:C581	R:R:N615	4.72	No	No	0	9	9
743	R:R:M582	R:R:S586	6.13	No	No	0	7	9
744	R:R:A583	R:R:P584	1.87	No	No	0	8	9
745	R:R:F611	R:R:P584	5.78	Yes	No	0	8	9
746	R:R:F588	R:R:I585	2.51	No	No	0	8	9
747	R:R:F611	R:R:I585	2.51	Yes	No	0	8	9
748	R:R:F587	R:R:S591	2.64	No	No	0	7	8
749	R:R:A589	R:R:F588	2.77	No	No	0	9	8
750	R:R:F588	R:R:S604	2.64	No	Yes	0	8	6
751	R:R:F594	R:R:I590	3.77	No	No	0	6	7
752	R:R:L598	R:R:S591	6.01	No	No	0	7	8
753	R:R:I599	R:R:N603	15.58	No	No	32	8	6
754	R:R:I599	R:R:S604	6.19	No	Yes	32	8	6
755	R:R:T600	R:R:T602	3.14	No	No	0	8	7
756	R:R:K605	R:R:V601	6.07	No	No	0	9	8
757	R:R:N603	R:R:S604	2.98	No	Yes	32	6	6
758	R:R:L607	R:R:N603	2.75	No	No	0	8	6
759	R:R:F611	R:R:L607	3.65	Yes	No	0	8	8
760	R:R:F611	R:R:L610	6.09	Yes	No	0	8	7
761	R:R:F611	R:R:I614	3.77	Yes	No	0	8	8
762	R:R:N615	R:R:N619	6.81	No	No	0	9	9
763	R:R:N619	R:R:Y623	5.81	No	Yes	0	9	9
764	R:R:F621	R:R:I625	11.3	No	No	0	8	7
765	R:R:L622	R:R:Y623	5.86	No	Yes	0	9	9
766	R:R:A624	R:R:F630	8.32	Yes	Yes	13	7	8
767	R:R:T627	R:R:T629	6.28	No	No	0	9	6
768	R:R:F630	R:R:T627	2.59	Yes	No	0	8	9
769	R:R:K628	R:R:R632	9.9	No	No	0	7	6
770	R:R:F635	R:R:Q631	7.03	No	No	0	4	6
771	R:R:L636	R:R:R632	2.43	No	No	0	3	6
772	R:R:F634	R:R:F635	6.43	No	No	0	5	4
773	R:R:F634	R:R:L638	19.49	No	No	0	5	4
774	R:R:F641	R:R:L637	2.44	No	No	0	2	7
775	R:R:C643	R:R:L638	3.17	No	No	0	2	4
776	R:R:C644	R:R:S639	6.89	No	No	0	4	5
777	R:R:P597	R:R:V596	1.77	No	No	0	5	5
778	R:R:G376	R:R:M375	1.75	No	No	0	7	2
779	R:R:G409	R:R:M408	1.75	No	Yes	0	9	8
780	N:N:G42	N:N:K40	1.74	No	No	0	7	7
781	L:L:C111	L:L:S81	1.72	No	No	0	9	9
782	R:R:G71	R:R:L72	1.71	No	No	0	5	7
783	R:R:A373	R:R:S616	1.71	No	No	0	9	9
784	R:R:A404	R:R:S453	1.71	No	No	0	8	8
785	R:R:A49	R:R:V37	1.7	No	No	0	4	2
786	R:R:G166	R:R:N167	1.7	No	No	0	4	7
787	R:R:A483	R:R:V393	1.7	No	No	0	7	8
788	N:N:C130	N:N:T48	1.69	Yes	No	0	9	5
789	N:N:C130	N:N:T129	1.69	Yes	No	0	9	4
790	R:R:D39	R:R:G40	1.68	No	No	0	4	5
791	R:R:A538	R:R:T458	1.68	No	No	0	9	8
792	R:R:A618	R:R:T577	1.68	No	No	0	7	9
793	N:N:L25	N:N:P24	1.64	No	No	0	1	3
794	N:N:G67	N:N:Q66	1.64	No	No	0	4	5
795	N:N:L89	N:N:P90	1.64	Yes	No	0	8	8
796	R:R:L122	R:R:P123	1.64	Yes	No	0	8	4
797	R:R:G171	R:R:Q170	1.64	No	No	0	4	3
798	R:R:L273	R:R:P345	1.64	Yes	No	0	7	9
799	R:R:C617	R:R:I369	1.64	No	No	0	9	8
800	R:R:C545	R:R:I541	1.64	Yes	No	0	6	4
801	R:R:C543	R:R:I547	1.64	No	No	0	7	5
802	N:N:S101	N:N:S86	1.63	No	No	21	6	8
803	R:R:N215	R:R:P238	1.63	No	No	0	1	9
804	R:R:S437	R:R:S440	1.63	No	No	0	2	4
805	R:R:N555	R:R:P556	1.63	No	No	0	7	6
806	N:N:S86	N:N:V99	1.62	No	No	21	8	3
807	N:N:S101	N:N:V99	1.62	No	No	21	6	3
808	R:R:A593	R:R:I528	1.62	No	No	0	7	6
809	R:R:A568	R:R:I567	1.62	No	No	0	8	7
810	R:R:A618	R:R:I614	1.62	No	No	0	7	8
811	R:R:A624	R:R:I625	1.62	Yes	No	0	7	7
812	L:L:A105	L:L:K87	1.61	No	No	0	4	5
813	R:R:A560	R:R:K563	1.61	No	No	0	3	5
814	R:R:S253	R:R:T274	1.6	No	No	0	7	9
815	N:N:T51	N:N:V49	1.59	Yes	No	0	9	6
816	R:R:C44	R:R:L42	1.59	No	No	0	5	3
817	R:R:C545	R:R:L462	1.59	Yes	No	0	6	5
818	R:R:T530	R:R:V526	1.59	No	No	0	4	4
819	L:L:P45	L:L:Q44	1.58	No	Yes	0	3	3
820	L:L:E38	L:L:P48	1.57	No	No	0	4	6
821	R:R:T162	R:R:T163	1.57	No	No	0	3	3
822	R:R:T251	R:R:T272	1.57	Yes	No	0	4	6
823	R:R:T521	R:R:T522	1.57	No	No	0	5	4
824	L:L:N76	N:N:A103	1.56	No	No	0	9	9
825	R:R:I533	R:R:V537	1.54	No	No	0	6	4
826	R:R:I549	R:R:V553	1.54	No	No	0	9	7
827	N:N:H126	N:N:P127	1.53	Yes	No	0	3	8
828	N:N:A111	N:N:Q109	1.52	No	No	0	5	3
829	R:R:K62	R:R:V63	1.52	No	No	0	4	4
830	R:R:M487	R:R:V459	1.52	No	No	0	7	4
831	R:R:I468	R:R:T467	1.52	No	No	0	7	8
832	R:R:M517	R:R:V519	1.52	No	No	0	8	6
833	R:R:A593	R:R:Q525	1.52	No	No	0	7	6
834	R:R:I533	R:R:T530	1.52	No	No	0	6	4
835	N:N:G95	N:N:R94	1.5	No	No	0	5	4
836	R:R:G71	R:R:R70	1.5	No	No	0	5	2
837	R:R:L414	R:R:S417	1.5	No	No	0	4	4
838	R:R:L502	R:R:S440	1.5	No	No	0	7	4
839	R:R:L496	R:R:S495	1.5	No	No	0	3	3
840	R:R:L608	R:R:S604	1.5	No	Yes	0	8	6
841	R:R:L598	R:R:V596	1.49	No	No	0	7	5
842	N:N:N50	N:N:V49	1.48	No	No	0	8	6
843	R:R:L72	R:R:T48	1.47	No	No	0	7	2
844	R:R:L51	R:R:T52	1.47	No	No	0	5	3
845	R:R:L457	R:R:T461	1.47	No	Yes	0	9	8
846	R:R:I468	R:R:I549	1.47	No	No	0	7	9
847	L:L:N90	L:L:T104	1.46	No	No	0	4	9
848	L:L:N102	L:L:T104	1.46	No	No	0	9	9
849	R:R:G334	R:R:Y333	1.45	No	No	0	3	1
850	N:N:P27	N:N:R26	1.44	No	No	0	4	5
851	N:N:L72	N:N:M61	1.41	No	No	0	3	6
852	R:R:E188	R:R:T163	1.41	No	No	0	5	3
853	R:R:K258	R:R:N428	1.4	No	Yes	0	5	6
854	R:R:D432	R:R:I431	1.4	No	Yes	0	4	8
855	R:R:C543	R:R:F540	1.4	No	No	0	7	4
856	R:R:K563	R:R:N562	1.4	No	No	0	5	4
857	R:R:P338	R:R:Y333	1.39	No	No	0	3	1
858	R:R:L410	R:R:L414	1.38	Yes	No	0	4	4
859	R:R:L381	R:R:N377	1.37	No	Yes	0	5	9
860	R:R:K628	R:R:Q631	1.36	No	No	0	7	6
861	R:R:D633	R:R:L637	1.36	No	No	0	8	7
862	R:R:A281	R:R:Y427	1.33	No	No	0	8	7
863	R:R:F594	R:R:V596	1.31	No	No	0	6	5
864	R:R:E211	R:R:Q235	1.27	No	No	0	2	4
865	R:R:F145	R:R:I120	1.26	No	Yes	0	3	5
866	R:R:D475	R:R:H473	1.26	No	No	0	4	4
867	N:N:K22	N:N:R28	1.24	No	No	0	1	2
868	R:R:M559	R:R:R554	1.24	No	No	0	2	5
869	R:R:F641	R:R:K640	1.24	No	No	0	2	4
870	L:L:N90	L:L:R91	1.21	No	No	0	4	4
871	R:R:N284	R:R:R283	1.21	No	No	0	5	3
872	R:R:L480	R:R:R481	1.21	No	No	0	3	3
873	R:R:M571	R:R:Y550	1.2	No	No	0	8	9
874	R:R:E270	R:R:R342	1.16	No	No	0	6	4

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:N39	8.23167	6	6	8
2	L:L:F42	6.24429	7	6	6
3	L:L:Q44	3.0325	4	6	3
4	L:L:I49	4.8725	4	6	5
5	L:L:C52	5.67	4	5	9
6	L:L:F57	6.345	4	7	7
7	L:L:Y61	9.31167	6	7	8
8	L:L:T63	7.44	4	2	9
9	L:L:S67	5.7975	4	2	7
10	L:L:L72	5.6275	4	15	3
11	L:L:C84	4.165	4	5	9
12	L:L:H103	7.28	5	5	9
13	L:L:C106	4.5725	4	5	9
14	L:L:K115	5.1175	4	2	9
15	N:N:E41	7.0325	4	0	6
16	N:N:T51	3.435	4	7	9
17	N:N:I53	6.8275	4	7	8
18	N:N:C54	5.415	4	9	9
19	N:N:Y57	5.0375	4	0	6
20	N:N:V64	4.6675	4	6	6
21	N:N:P73	5.0575	4	3	2
22	N:N:Y79	7.52571	7	9	8
23	N:N:L89	5.8625	4	10	8
24	N:N:C92	4.745	4	10	9
25	N:N:R115	5.75	4	2	7
26	N:N:D119	6.1025	4	2	9
27	N:N:P123	3.395	4	0	4
28	N:N:K124	4.912	5	2	7
29	N:N:H126	4.096	5	2	3
30	N:N:C130	3.1175	4	2	9
31	R:R:P45	8.368	5	4	5
32	R:R:P47	6.2975	4	0	1
33	R:R:Y58	5.865	4	2	5
34	R:R:L59	4.46	4	0	7
35	R:R:F69	9.4825	4	1	8
36	R:R:K77	6.664	5	19	5
37	R:R:I78	8.9525	4	1	8
38	R:R:I80	4.7075	4	22	8
39	R:R:S81	4.41	4	2	6
40	R:R:Q82	6.878	5	2	6
41	R:R:F94	9.54333	6	1	9
42	R:R:D95	5.75	4	12	6
43	R:R:E102	10.7175	4	19	7
44	R:R:I103	4.934	5	1	8
45	R:R:Q106	3.93833	6	2	7
46	R:R:N107	5.04833	6	2	7
47	R:R:L111	7.3	4	4	7
48	R:R:Y113	6.6375	4	4	1
49	R:R:I114	7.235	4	4	8
50	R:R:F119	5.206	5	1	8
51	R:R:I120	3.54	4	12	5
52	R:R:L122	5.2525	4	1	8
53	R:R:L125	7.4875	4	1	9
54	R:R:K126	9.865	4	0	5
55	R:R:Y127	15.8875	4	0	6
56	R:R:L128	4.795	4	1	8
57	R:R:C131	4.255	4	2	7
58	R:R:T133	6.164	5	4	8
59	R:R:I135	6.7525	4	4	7
60	R:R:F138	7.02	6	1	5
61	R:R:F151	4.74833	6	1	5
62	R:R:I155	5.41167	6	1	8
63	R:R:D157	5.5175	4	15	6
64	R:R:I164	6.69	4	1	7
65	R:R:F169	5.9325	4	1	6
66	R:R:M172	4.424	5	1	6
67	R:R:V177	4.386	5	1	3
68	R:R:L179	6.03	5	1	8
69	R:R:K180	10.8525	4	3	5
70	R:R:L181	4.86	4	1	8
71	R:R:Y182	10.044	5	3	6
72	R:R:N184	6.60333	6	1	9
73	R:R:F186	11.285	4	1	8
74	R:R:F194	4.6	4	1	9
75	R:R:L199	4.896	5	1	8
76	R:R:S201	3.8375	4	3	5
77	R:R:E203	9.2	4	3	5
78	R:R:K205	6.964	5	3	7
79	R:R:E206	3.8275	4	0	4
80	R:R:N207	8.682	5	1	9
81	R:R:L210	9.1775	4	1	8
82	R:R:M213	4.0725	4	0	6
83	R:R:D228	9.76	5	3	9
84	R:R:S230	7.3025	4	3	9
85	R:R:L242	5.0725	4	16	9
86	R:R:R247	5.2475	4	0	5
87	R:R:T251	3.9325	4	3	4
88	R:R:F265	7.444	5	16	7
89	R:R:L273	6.57	4	26	7
90	R:R:F282	4.58	5	0	8
91	R:R:T340	6.3925	4	0	4
92	R:R:D355	7.2725	4	8	7
93	R:R:I356	5.7075	4	8	8
94	R:R:M357	4.902	5	8	7
95	R:R:Y359	5.972	5	8	6
96	R:R:L362	5.81	4	8	8
97	R:R:N377	4.655	4	0	9
98	R:R:L384	4.0625	4	13	6
99	R:R:R395	3.892	5	0	7
100	R:R:D405	4.31	4	0	9
101	R:R:M408	4.015	6	11	8
102	R:R:L410	2.3325	4	11	4
103	R:R:Y411	7.16714	7	11	7
104	R:R:N428	6.505	4	25	6
105	R:R:I431	5.1025	4	0	8
106	R:R:G443	4.1525	4	14	9
107	R:R:F444	5.31	4	0	8
108	R:R:F445	3.605	4	11	7
109	R:R:F448	6.185	4	27	8
110	R:R:I460	4.48	4	17	9
111	R:R:T461	7.1975	4	29	8
112	R:R:W465	5.292	5	0	5
113	R:R:H466	3.4725	4	30	5
114	R:R:W491	6.454	5	27	5
115	R:R:I497	6.085	4	28	5
116	R:R:S506	2.92	4	0	8
117	R:R:C514	6.5725	4	14	9
118	R:R:D518	4.185	4	31	7
119	R:R:I531	4.9275	4	28	6
120	R:R:L532	4.035	4	0	9
121	R:R:F539	4.655	4	0	8
122	R:R:C545	3.285	4	0	6
123	R:R:Y546	8.7275	4	29	9
124	R:R:K570	7.1125	4	0	9
125	R:R:S604	3.3275	4	32	6
126	R:R:F611	4.36	5	0	8
127	R:R:Y623	4.854	5	0	9
128	R:R:A624	4.1375	4	13	7
129	R:R:F630	7.612	5	13	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:F57	N:N:A55	22.6346	2.77	Yes	No	7	7	8
2	N:N:A55	N:N:I53	22.3026	3.25	No	Yes	7	8	8
3	L:L:Y61	N:N:I53	21.2244	13.3	Yes	Yes	7	8	8
4	L:L:Y61	N:N:T51	19.8039	3.75	Yes	Yes	7	8	9
5	N:N:T51	N:N:Y102	18.7641	2.5	Yes	No	0	9	6
6	N:N:E85	N:N:Y102	11.825	15.71	No	No	0	6	6
7	N:N:E85	N:N:R83	11.4533	5.82	No	No	0	6	4
8	N:N:R83	N:N:V104	11.0809	3.92	No	No	0	4	9
9	N:N:T52	N:N:V104	10.7079	3.17	No	No	0	8	9
10	N:N:P31	N:N:T52	10.3343	5.25	No	No	0	7	8
11	L:L:A86	L:L:Y89	13.9516	4	No	No	0	9	4
12	L:L:Y89	R:R:K126	16.6914	2.39	No	Yes	0	4	5
13	R:R:K126	R:R:Y127	18.3827	21.5	Yes	Yes	0	5	6
14	R:R:E102	R:R:Y127	19.8533	7.86	Yes	Yes	0	7	6
15	N:N:P123	R:R:R53	22.1979	2.88	Yes	No	0	4	2
16	L:L:E80	N:N:P123	22.7048	3.14	No	Yes	0	9	4
17	L:L:E80	L:L:R59	22.0712	6.98	No	No	0	9	8
18	L:L:F57	L:L:R59	21.7547	16.03	Yes	No	0	7	8
19	L:L:A86	L:L:H103	11.4578	4.39	No	Yes	5	9	9
20	N:N:K124	R:R:S55	20.7429	3.06	Yes	No	0	7	4
21	R:R:E79	R:R:S55	20.4755	4.31	No	No	0	5	4
22	R:R:E79	R:R:R53	20.223	30.24	No	No	0	5	2
23	N:N:K124	R:R:Q82	21.3398	6.78	Yes	Yes	2	7	6
24	R:R:L104	R:R:Q106	20.4365	3.99	No	Yes	0	5	7
25	R:R:E102	R:R:L104	20.1668	14.58	Yes	No	0	7	5
26	R:R:N107	R:R:Q106	34.7602	3.96	Yes	Yes	2	7	7
27	L:L:K115	R:R:Q106	16.5913	2.71	Yes	Yes	2	9	7
28	L:L:T70	R:R:D84	63.8176	2.89	No	No	0	9	7
29	L:L:T70	R:R:Q82	24.0857	9.92	No	Yes	2	9	6
30	L:L:K115	R:R:E154	13.5666	4.05	Yes	No	0	9	7
31	R:R:E154	R:R:K180	12.87	10.8	No	Yes	0	7	5
32	R:R:D84	R:R:S85	69.3693	7.36	No	No	0	7	5
33	R:R:P60	R:R:S85	69.5499	1.78	No	No	0	5	5
34	R:R:L59	R:R:P60	69.73	3.28	Yes	No	0	7	5
35	R:R:L56	R:R:L59	65.5732	6.92	No	Yes	0	6	7
36	R:R:I80	R:R:L56	65.7256	5.71	Yes	No	0	8	6
37	R:R:I105	R:R:I80	66.213	4.42	No	Yes	0	8	8
38	R:R:I105	R:R:I130	66.3787	10.3	No	No	0	8	8
39	R:R:I130	R:R:I155	69.5064	4.42	No	Yes	0	8	8
40	R:R:I155	R:R:L153	17.1804	2.85	Yes	No	1	8	9
41	R:R:I155	R:R:N184	70.2398	9.91	Yes	Yes	1	8	9
42	R:R:L179	R:R:L181	32.745	2.77	Yes	Yes	1	8	8
43	R:R:L179	R:R:V177	14.2142	4.47	Yes	Yes	1	8	3
44	R:R:T197	R:R:V177	14.5739	3.17	No	Yes	0	5	3
45	R:R:G196	R:R:T197	24.4399	1.82	No	No	0	6	5
46	R:R:G196	R:R:N195	23.3358	5.09	No	No	0	6	5
47	R:R:N195	R:R:Q170	21.1257	7.92	No	No	0	5	3
48	R:R:N167	R:R:Q170	18.9129	18.49	No	No	0	7	3
49	R:R:G166	R:R:N167	16.6976	1.7	No	No	0	4	7
50	R:R:G166	R:R:Q190	15.5889	3.29	No	No	0	4	2
51	R:R:Q190	R:R:T163	14.4796	8.5	No	No	0	2	3
52	R:R:L179	R:R:L199	13.6761	4.15	Yes	Yes	1	8	8
53	R:R:L199	R:R:T197	11.3006	2.95	Yes	No	0	8	5
54	R:R:L181	R:R:L204	13.0695	4.15	Yes	No	0	8	9
55	R:R:N184	R:R:N207	85.8628	4.09	Yes	Yes	1	9	9
56	R:R:E188	R:R:T163	11.1479	1.41	No	No	0	5	3
57	R:R:N207	R:R:T232	96.6081	4.39	Yes	No	1	9	9
58	R:R:I229	R:R:T232	96.9418	12.16	No	No	0	7	9
59	R:R:I229	R:R:L227	100	2.85	No	No	0	7	8
60	R:R:L227	R:R:L248	99.9812	4.15	No	No	0	8	9
61	R:R:F265	R:R:L248	99.5877	3.65	Yes	No	0	7	9
62	R:R:F265	R:R:P260	94.4792	10.11	Yes	No	16	7	6
63	R:R:L259	R:R:P260	95.0901	4.93	No	No	0	6	6
64	R:R:L259	R:R:N428	98.2207	4.12	No	Yes	0	6	6
65	R:R:H429	R:R:N428	97.8821	17.86	No	Yes	25	6	6
66	R:R:H429	R:R:T422	97.9916	9.58	No	No	0	6	9
67	R:R:D355	R:R:T422	97.9439	4.34	Yes	No	0	7	9
68	R:R:D355	R:R:I356	53.496	2.8	Yes	Yes	8	7	8
69	R:R:I356	R:R:I513	11.4182	2.94	Yes	No	0	8	9
70	R:R:I513	R:R:V511	11.1602	4.61	No	No	0	9	9
71	R:R:M517	R:R:V511	10.9064	4.56	No	No	0	8	9
72	R:R:I356	R:R:M357	43.1303	7.29	Yes	Yes	8	8	7
73	R:R:D355	R:R:D419	42.6929	9.31	Yes	No	8	7	9
74	R:R:D419	R:R:M357	42.5483	4.16	No	Yes	8	9	7
75	R:R:I366	R:R:M357	82.0794	4.37	No	Yes	8	9	7
76	R:R:I366	R:R:L412	82.4228	2.85	No	No	0	9	8
77	R:R:L412	R:R:Y411	82.0592	10.55	No	Yes	0	8	7
78	R:R:M408	R:R:Y411	60.8998	4.79	Yes	Yes	11	8	7
79	R:R:M408	R:R:S616	59.4305	7.67	Yes	No	0	8	9
80	R:R:D405	R:R:S616	56.9779	2.94	Yes	No	0	9	9
81	R:R:D405	R:R:N377	24.075	4.04	Yes	Yes	0	9	9
82	R:R:N377	R:R:S402	16.308	5.96	Yes	No	0	9	8
83	R:R:S402	R:R:V380	15.8508	4.85	No	No	0	8	9
84	R:R:F630	R:R:V380	13.5686	5.24	Yes	No	13	8	9
85	R:R:F630	R:R:L384	10.1312	4.87	Yes	Yes	13	8	6
86	R:R:D405	R:R:L401	34.7592	5.43	Yes	No	0	9	8
87	R:R:L401	R:R:N619	32.952	8.24	No	No	0	8	9
88	R:R:N619	R:R:Y623	26.1324	5.81	No	Yes	0	9	9
89	R:R:L574	R:R:Y623	22.1547	3.52	No	Yes	0	9	9
90	R:R:L574	R:R:Y546	19.1511	9.38	No	Yes	0	9	9
91	R:R:T461	R:R:Y546	13.525	8.74	Yes	Yes	29	8	9
92	R:R:C545	R:R:T461	12.5236	3.38	Yes	Yes	0	6	8
93	L:L:T70	R:R:N107	39.5382	2.92	No	Yes	2	9	7
94	R:R:L181	R:R:N184	13.8646	8.24	Yes	Yes	1	8	9
95	R:R:L204	R:R:N207	13.0802	4.12	No	Yes	0	9	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:R66	R:R:Y58	6.17	0	No	Yes	6	5	0	1
L:L:S67	R:R:Y58	5.09	2	Yes	Yes	7	5	0	1
L:L:K69	R:R:D84	4.15	0	No	No	5	7	0	1
L:L:K69	R:R:K109	7.18	0	No	No	5	6	0	1
L:L:T70	R:R:Q82	9.92	2	No	Yes	9	6	0	1
L:L:T70	R:R:D84	2.89	2	No	No	9	7	0	1
L:L:T70	R:R:N107	2.92	2	No	Yes	9	7	0	1
L:L:M71	R:R:N107	5.61	2	No	Yes	9	7	0	1
L:L:L72	R:R:K109	8.46	15	Yes	No	3	6	0	1
L:L:L72	R:R:N132	6.87	15	Yes	No	3	8	0	1
L:L:L72	R:R:D157	2.71	15	Yes	Yes	3	6	0	1
L:L:V73	R:R:N132	2.96	15	No	No	7	8	0	1
L:L:V73	R:R:D157	5.84	15	No	Yes	7	6	0	1
L:L:Y89	R:R:K126	2.39	0	No	Yes	4	5	0	1
L:L:F98	R:R:F335	6.43	0	No	No	3	1	0	1
L:L:S109	R:R:K77	4.59	0	No	Yes	8	5	0	1
L:L:T110	R:R:K77	3	19	No	Yes	9	5	0	1
L:L:T110	R:R:E102	4.23	19	No	Yes	9	7	0	1
L:L:Y112	R:R:Y127	31.77	0	No	Yes	5	6	0	1
L:L:Y113	R:R:K180	2.39	0	No	Yes	4	5	0	1
L:L:K115	R:R:Q106	2.71	2	Yes	Yes	9	7	0	1
L:L:K115	R:R:C131	3.23	2	Yes	Yes	9	7	0	1
L:L:K115	R:R:E154	4.05	2	Yes	No	9	7	0	1
L:L:S116	R:R:Y182	2.54	3	No	Yes	9	6	0	1
N:N:R63	R:R:Y331	2.06	0	No	No	4	1	0	1
N:N:P70	R:R:R247	2.88	0	No	Yes	4	5	0	1
N:N:R115	R:R:C131	5.57	2	Yes	Yes	7	7	0	1
N:N:R115	R:R:C156	5.57	2	Yes	No	7	7	0	1
N:N:R115	R:R:E206	2.33	2	Yes	Yes	7	4	0	1
N:N:S116	R:R:E206	4.31	0	No	Yes	6	4	0	1
N:N:D119	R:R:Q106	2.61	2	Yes	Yes	9	7	0	1
N:N:D119	R:R:N107	6.73	2	Yes	Yes	9	7	0	1
N:N:P123	R:R:R53	2.88	0	Yes	No	4	2	0	1
N:N:K124	R:R:S55	3.06	2	Yes	No	7	4	0	1
N:N:K124	R:R:A57	6.42	2	Yes	No	7	4	0	1
N:N:K124	R:R:S81	3.06	2	Yes	Yes	7	6	0	1
N:N:K124	R:R:Q82	6.78	2	Yes	Yes	7	6	0	1
N:N:H126	R:R:Y58	5.44	2	Yes	Yes	3	5	0	1
N:N:D131	R:R:E32	11.69	0	No	No	5	3	0	1
R:R:E32	R:R:P33	7.86	0	No	No	3	4	1	2
R:R:K77	R:R:R53	3.71	19	Yes	No	5	2	1	1
R:R:E79	R:R:R53	30.24	0	No	No	5	2	2	1
R:R:E79	R:R:S55	4.31	0	No	No	5	4	2	1
R:R:Q82	R:R:Y58	6.76	2	Yes	Yes	6	5	1	1
R:R:I76	R:R:K77	5.82	0	No	Yes	3	5	2	1
R:R:E102	R:R:K77	16.2	19	Yes	Yes	7	5	1	1
R:R:Q82	R:R:S81	4.33	2	Yes	Yes	6	6	1	1
R:R:Q106	R:R:S81	5.78	2	Yes	Yes	7	6	1	1
R:R:N107	R:R:S81	4.47	2	Yes	Yes	7	6	1	1
R:R:N107	R:R:Q82	6.6	2	Yes	Yes	7	6	1	1
R:R:D84	R:R:S85	7.36	0	No	No	7	5	1	2
R:R:K126	R:R:S101	6.12	0	Yes	No	5	5	1	2
R:R:E102	R:R:L104	14.58	19	Yes	No	7	5	1	2
R:R:E102	R:R:Y127	7.86	19	Yes	Yes	7	6	1	1
R:R:L104	R:R:Q106	3.99	0	No	Yes	5	7	2	1
R:R:N107	R:R:Q106	3.96	2	Yes	Yes	7	7	1	1
R:R:C131	R:R:Q106	4.58	2	Yes	Yes	7	7	1	1
R:R:K126	R:R:Y127	21.5	0	Yes	Yes	5	6	1	1
R:R:E148	R:R:K126	9.45	0	No	Yes	5	5	2	1
R:R:I152	R:R:Y127	2.42	0	No	Yes	4	6	2	1
R:R:E154	R:R:S129	2.87	0	No	No	7	7	1	2
R:R:C131	R:R:C156	3.64	2	Yes	No	7	7	1	1
R:R:D157	R:R:N132	6.73	15	Yes	No	6	8	1	1
R:R:E154	R:R:K180	10.8	0	No	Yes	7	5	1	1
R:R:D157	R:R:L159	6.79	15	Yes	No	6	3	1	2
R:R:K180	R:R:Y182	16.72	3	Yes	Yes	5	6	1	1
R:R:E203	R:R:K180	13.5	3	Yes	Yes	5	5	2	1
R:R:E203	R:R:Y182	12.35	3	Yes	Yes	5	6	2	1
R:R:K205	R:R:Y182	5.97	3	Yes	Yes	7	6	2	1
R:R:D228	R:R:Y182	12.64	3	Yes	Yes	9	6	2	1
R:R:E206	R:R:G183	3.27	0	Yes	No	4	7	1	2
R:R:D228	R:R:E203	5.2	3	Yes	Yes	9	5	2	2
R:R:E206	R:R:K205	5.4	0	Yes	Yes	4	7	1	2
R:R:D228	R:R:K205	9.68	3	Yes	Yes	9	7	2	2
R:R:R247	R:R:T226	6.47	0	Yes	No	5	4	1	2
R:R:Q246	R:R:R247	3.5	0	No	Yes	6	5	2	1
R:R:E270	R:R:R247	8.14	0	No	Yes	6	5	2	1
R:R:D330	R:R:Y331	5.75	0	No	No	4	1	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	7FII_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	1.78
Number of Linked Nodes	729
Number of Links	874
Number of Hubs	129
Number of Links mediated by Hubs	455
Number of Communities	32
Number of Nodes involved in Communities	206
Number of Links involved in Communities	287

Path Summary
Number Of Nodes in MetaPath	96
Number Of Links MetaPath	95
Number of Shortest Paths	538677
Length Of Smallest Path	3
Average Path Length	29.101
Length of Longest Path	72
Minimum Path Strength	1.335
Average Path Strength	6.0378
Maximum Path Strength	26.635
Minimum Path Correlation	0.71
Average Path Correlation	0.979921
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	2.38095
Average % Of Corr. Nodes	56.3248
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	40.6358
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process	• sexual reproduction • reproductive process • multicellular organismal reproductive process • female gamete generation • gamete generation • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • response to endogenous stimulus • biological regulation • hormone-mediated signaling pathway • cell communication • cellular response to endogenous stimulus • cellular response to chemical stimulus • response to hormone • response to chemical • cellular process • signal transduction • cellular response to hormone stimulus • apoptotic process • cell death • programmed cell death • G protein-coupled receptor signaling pathway • cell-cell signaling • protein-containing complex • cellular anatomical structure • extracellular region • pituitary gonadotropin complex • intracellular anatomical structure • cytoplasm • extracellular space • hormone activity • molecular function activator activity • molecular function regulator activity • signaling receptor regulator activity • follicle-stimulating hormone activity • receptor ligand activity • signaling receptor activator activity • cell population proliferation • positive regulation of cell population proliferation • regulation of cell population proliferation • positive regulation of biological process • positive regulation of cellular process • multicellular organismal process • system process • gonadotropin secretion • transport • hormone secretion • localization • secretion by cell • signal release • regulation of biological quality • secretion • regulation of hormone levels • follicle-stimulating hormone secretion • export from cell • establishment of localization • endocrine hormone secretion • endocrine process • hormone transport • phenol-containing compound metabolic process • modified amino acid metabolic process • metabolic process • hormone metabolic process • thyroid hormone generation • thyroid hormone metabolic process • developmental process • developmental growth • growth • organ growth • multicellular organism development • thyroid gland development • endocrine system development • gland development • animal organ development • anatomical structure development • system development • positive regulation of locomotion • regulation of cell motility • positive regulation of cell migration • regulation of locomotion • positive regulation of cell motility • regulation of cell migration • cell migration • cell motility • locomotion • regulation of signaling • regulation of signaling receptor activity • regulation of signal transduction • regulation of molecular function • regulation of response to stimulus • regulation of cell communication • regulation of steroid biosynthetic process • steroid metabolic process • regulation of lipid metabolic process • lipid biosynthetic process • regulation of primary metabolic process • positive regulation of metabolic process • positive regulation of biosynthetic process • positive regulation of lipid metabolic process • steroid biosynthetic process • regulation of biosynthetic process • regulation of steroid metabolic process • primary metabolic process • positive regulation of steroid biosynthetic process • biosynthetic process • positive regulation of lipid biosynthetic process • positive regulation of steroid metabolic process • regulation of lipid biosynthetic process • regulation of metabolic process • lipid metabolic process • regulation of growth • regulation of developmental growth • regulation of developmental process • negative regulation of developmental process • negative regulation of biological process • negative regulation of organ growth • negative regulation of developmental growth • negative regulation of growth • regulation of organ growth • regulation of multicellular organismal process • negative regulation of multicellular organismal process • luteinizing hormone secretion • ovulation cycle process • sex differentiation • development of primary female sexual characteristics • developmental process involved in reproduction • ovulation cycle • development of primary sexual characteristics • reproductive structure development • ovarian follicle development • rhythmic process • gonad development • reproductive system development • female gonad development • female sex differentiation • follicle-stimulating hormone signaling pathway • positive regulation of DNA-templated transcription • RNA metabolic process • positive regulation of macromolecule biosynthetic process • nucleobase-containing compound metabolic process • RNA biosynthetic process • nucleic acid biosynthetic process • DNA-templated transcription • regulation of RNA metabolic process • transcription by RNA polymerase II • positive regulation of macromolecule metabolic process • regulation of nucleobase-containing compound metabolic process • regulation of RNA biosynthetic process • regulation of transcription by RNA polymerase II • regulation of macromolecule metabolic process • positive regulation of transcription by RNA polymerase II • nucleobase-containing compound biosynthetic process • gene expression • macromolecule biosynthetic process • nucleic acid metabolic process • positive regulation of RNA metabolic process • regulation of gene expression • positive regulation of RNA biosynthetic process • regulation of macromolecule biosynthetic process • macromolecule metabolic process • regulation of DNA-templated transcription • membrane-bounded organelle • Golgi apparatus • membrane-enclosed lumen • intracellular membrane-bounded organelle • endomembrane system • intracellular organelle lumen • Golgi lumen • intracellular organelle • organelle lumen • organelle • follicle-stimulating hormone complex • choriogonadotropin hormone receptor activity • molecular transducer activity • protein-hormone receptor activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • choriogonadotropin hormone binding • binding • hormone binding • peptide receptor activity • G protein-coupled peptide receptor activity • luteinizing hormone receptor activity • male gonad development • male sex differentiation • development of primary male sexual characteristics • tube development • seminiferous tubule development • cellular response to nitrogen compound • cellular response to gonadotropin stimulus • cellular response to luteinizing hormone stimulus • response to luteinizing hormone • response to peptide hormone • cellular response to peptide hormone stimulus • response to oxygen-containing compound • response to nitrogen compound • cellular response to oxygen-containing compound • response to gonadotropin • spermatogenesis • male gamete generation • regulation of hormone biosynthetic process • regulation of hormone metabolic process • hormone biosynthetic process • regulation of steroid hormone biosynthetic process • nervous system process • cognition • genitalia development • male genitalia development • luteinizing hormone signaling pathway • adenylate cyclase-activating G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • uterus development • phospholipase C-activating G protein-coupled receptor signaling pathway • development of secondary male sexual characteristics • development of secondary sexual characteristics • regulation of inositol phosphate biosynthetic process • regulation of inositol trisphosphate biosynthetic process • alcohol metabolic process • inositol phosphate metabolic process • positive regulation of phosphate metabolic process • positive regulation of inositol trisphosphate biosynthetic process • regulation of small molecule metabolic process • phosphate-containing compound metabolic process • polyol biosynthetic process • inositol trisphosphate metabolic process • small molecule metabolic process • phosphorus metabolic process • regulation of carbohydrate metabolic process • carbohydrate metabolic process • polyol metabolic process • regulation of alcohol biosynthetic process • positive regulation of phosphorus metabolic process • small molecule biosynthetic process • inositol trisphosphate biosynthetic process • carbohydrate biosynthetic process • positive regulation of inositol phosphate biosynthetic process • organophosphate metabolic process • organophosphate biosynthetic process • inositol phosphate biosynthetic process • alcohol biosynthetic process • regulation of phosphorus metabolic process • regulation of carbohydrate biosynthetic process • positive regulation of carbohydrate metabolic process • positive regulation of small molecule metabolic process • positive regulation of alcohol biosynthetic process • G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger • intracellular membraneless organelle • centrosome • microtubule organizing center • cytoskeleton • centriolar satellite • membraneless organelle • microtubule cytoskeleton • cell periphery • plasma membrane • membrane • endosome • intracellular vesicle • cytoplasmic vesicle • vesicle • protein binding • G-protein beta-subunit binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • cellular response to monoamine stimulus • response to ketone • response to prostaglandin • response to lipid • response to alcohol • cellular response to prostaglandin stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • cellular response to lipid • response to prostaglandin E • cellular response to ketone • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • cytoskeletal protein binding • spectrin binding • protein-containing complex binding • enzyme binding • GTPase binding • phosphoric ester hydrolase activity • alkylglycerophosphoethanolamine phosphodiesterase activity • hydrolase activity, acting on ester bonds • phosphoric diester hydrolase activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • positive regulation of cytosolic calcium ion concentration • sensory perception of chemical stimulus • sensory perception • sensory perception of taste • sensory organ development • eye development • retina development in camera-type eye • visual system development • camera-type eye development • sensory system development • response to decreased oxygen levels • cellular response to oxygen levels • cellular response to hypoxia • cellular response to decreased oxygen levels • cellular response to stress • response to hypoxia • response to stress • response to oxygen levels • response to abiotic stimulus • muscle cell apoptotic process • striated muscle cell apoptotic process • cardiac muscle cell apoptotic process • photoreceptor inner segment • somatodendritic compartment • cell projection • dendrite • dendritic tree • neuron projection • plasma membrane bounded cell projection • non-motile cilium • 9+0 non-motile cilium • cilium • photoreceptor outer segment • photoreceptor cell cilium • ciliary membrane • photoreceptor outer segment membrane • bounding membrane of organelle • plasma membrane region • organelle membrane • cell projection membrane • synapse • cell junction • cell body
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Cystine-knot cytokines • Cystine-knot cytokines • Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Cystine-knot cytokines • Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	L
Protein	hCG
UniProt	P01215
Sequence	>7FII_nogp_Chain_L Q D C P E C T L Q E N P F F S Q P G A P I L Q C M G C C F S R A Y P T P L R S K K T M L V Q K N V T S E S T C C V A K S Y N R V T V M G G F K V E N H T A C H C S T C Y Y H K S Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	N
Protein	hCG
UniProt	P0DN86
Sequence	>7FII_nogp_Chain_N K E P L R P R C R P I N A T L A V E K E G C P V C I T V N T T I C A G Y C P T M T R V L Q G V L P A L P Q V V C N Y R D V R F E S I R L P G C P R G V N P V V S Y A V A L S C Q C A L C R R S T T D C G G P K D H P L T C D Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	R
Protein	Receptor
UniProt	P22888
Sequence	>7FII_nogp_Chain_R E P C N C V P D G A L R C P G P T A G L T R L S L A Y L P V K V I P S Q A F R G L N E V I K I E I S Q I D S L E R I E A N A F D N L L N L S E I L I Q N T K N L R Y I E P G A F I N L P R L K Y L S I C N T G I R K F P D V T K V F S S E S N F I L E I C D N L H I T T I P G N A F Q G M N N E S V T L K L Y G N G F E E V Q S H A F N G T T L T S L E L K E N V H L E K M H N G A F R G A T G P K T L D I S S T K L Q A L P S Y G L E S I Q R L I A T S S Y S L K K L P S R E T F V N L L E A T L T Y P S H C C A F R N L P D Y E Y G F C L P K T P R C A P E P D A F N P C E D I M G Y D F L R V L I W L I N I L A I M G N M T V L F V L L T S R Y K L T V P R F L M C N L S F A D F C M G L Y L L L I A S V D S Q T K G Q Y Y N H A I D W Q T G S G C S T A G F F T V F A S E L S V Y T L T V I T L E R W H T I T Y A I H L D Q K L R L R H A I L I M L G G W L F S S L I A M L P L V G V S N Y M K V S I C F P M D V E T T L S Q V Y I L T I L I L N V V A F F I I C A C Y I K I Y F A V R N P E L M A T N K D T K I A K K M A I L I F T D F T C M A P I S F F A I S A A F K V P L I T V T N S K V L L V L F Y P I N S C A N P F L Y A I F T K T F Q R D F F L L L S K F G C C Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	5GLH	A	Peptide	Endothelin	ET_B	Homo sapiens	Endothelin-1	-	-	2.8	2016-09-07	doi.org/10.1038/nature19319
	5OLH	A	Nucleotide	Adenosine	A_2A	Homo sapiens	Vipadenant	Na	-	2.6	2018-01-17	doi.org/10.1038/s41598-017-18570-w
	7FIG	A	Protein	Glycoprotein Hormone	LH	Homo sapiens	hCG	-	chim(NtGi1L-Gs)/β1/γ2	3.9	2021-09-29	doi.org/10.1038/s41586-021-03924-2
	7FIG (No Gprot)	A	Protein	Glycoprotein Hormone	LH	Homo sapiens	hCG	-		3.9	2021-09-29	doi.org/10.1038/s41586-021-03924-2
	7FIH	A	Protein	Glycoprotein Hormone	LH	Homo sapiens	hCG	Org43553	chim(NtGi1-Gs)/β1/γ2	3.2	2021-09-29	doi.org/10.1038/s41586-021-03924-2
	7FIH (No Gprot)	A	Protein	Glycoprotein Hormone	LH	Homo sapiens	hCG	Org43553		3.2	2021-09-29	doi.org/10.1038/s41586-021-03924-2
	7FII	A	Protein	Glycoprotein Hormone	LH	Homo sapiens	hCG	-	chim(NtGi1-Gs)/β1/γ2	4.3	2021-09-29	doi.org/10.1038/s41586-021-03924-2
	7FII (No Gprot)	A	Protein	Glycoprotein Hormone	LH	Homo sapiens	hCG	-		4.3	2021-09-29	doi.org/10.1038/s41586-021-03924-2
	7FIJ	A	Protein	Glycoprotein Hormone	LH	Homo sapiens	-	-	-	3.8	2021-09-29	doi.org/10.1038/s41586-021-03924-2
	6ZFZ	A	Amine	Acetylcholine (muscarinic)	M₁	Homo sapiens	77-LH-28-1	-	-	2.17	2021-10-06	doi.org/10.1016/j.cell.2021.11.001
	9LHQ	B2	Orphan	Orphan	GPR155	Homo sapiens	-	-	-	3.46	2025-12-10	10.1016/j.scib.2025.09.012
	9LHV	B2	Orphan	Orphan	GPR155; GPR155	Homo sapiens	-	-	-	2.79	2025-12-10	10.1016/j.scib.2025.09.012
	9LHX	B2	Orphan	Orphan	GPR155; GPR155	Homo sapiens	-	-	-	5.62	2025-12-10	10.1016/j.scib.2025.09.012

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

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