psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:M48	R:R:W330	20.94	No	Yes	0	6	6
2	R:R:G91	R:R:I55	3.53	No	Yes	0	7	7
3	R:R:I55	R:R:S336	9.29	Yes	No	0	7	9
4	R:R:G58	R:R:P340	4.06	No	No	0	8	9
5	R:R:D87	R:R:N59	6.73	Yes	No	0	9	9
6	R:R:N59	R:R:P340	4.89	No	No	0	9	9
7	R:R:P340	R:R:V62	3.53	No	No	0	9	9
8	R:R:C344	R:R:V62	6.83	No	No	0	6	9
9	R:R:A65	R:R:F353	4.16	No	No	0	7	7
10	R:R:I66	R:R:N77	11.33	Yes	Yes	2	7	9
11	R:R:I66	R:R:T81	4.56	Yes	No	0	7	5
12	R:R:F349	R:R:I66	5.02	Yes	Yes	2	8	7
13	R:R:R355	R:R:S68	6.59	No	No	0	4	5
14	R:R:R355	R:R:T69	9.06	No	No	0	4	6
15	R:R:Q70	R:R:Q73	16.64	No	No	0	6	7
16	R:R:D348	R:R:R71	5.96	No	No	0	6	5
17	R:R:L72	R:R:N77	4.12	No	Yes	2	8	9
18	R:R:F349	R:R:L72	9.74	Yes	No	2	8	8
19	R:R:N77	R:R:T74	10.24	Yes	No	0	9	7
20	R:R:L75	R:R:M153	5.65	No	No	0	6	6
21	R:R:D138	R:R:T76	4.34	Yes	No	0	9	8
22	R:R:F349	R:R:N77	6.04	Yes	Yes	2	8	9
23	R:R:L78	R:R:R155	8.5	No	No	0	5	3
24	R:R:F79	R:R:V134	7.87	Yes	No	0	8	5
25	R:R:F79	R:R:I135	3.77	Yes	No	0	8	9
26	R:R:D138	R:R:F79	8.36	Yes	Yes	0	9	8
27	R:R:F79	R:R:I162	5.02	Yes	No	0	8	7
28	R:R:S82	R:R:T131	7.99	No	No	0	9	8
29	R:R:I162	R:R:S82	4.64	No	No	0	7	9
30	R:R:S82	R:R:W166	6.18	No	No	0	9	9
31	R:R:L83	R:R:T131	5.9	No	No	0	9	8
32	R:R:L132	R:R:L83	5.54	No	No	5	8	9
33	R:R:L83	R:R:N339	6.87	No	Yes	5	9	9
34	R:R:D87	R:R:S128	7.36	Yes	No	0	9	9
35	R:R:D87	R:R:S336	10.31	Yes	No	0	9	9
36	R:R:D87	R:R:N339	6.73	Yes	Yes	0	9	9
37	R:R:L88	R:R:L92	6.92	No	No	0	7	5
38	R:R:G91	R:R:V90	3.68	No	No	0	7	8
39	R:R:S336	R:R:V90	4.85	No	No	0	9	8
40	R:R:L120	R:R:L93	4.15	No	No	0	5	4
41	R:R:D121	R:R:V94	10.22	Yes	No	1	7	7
42	R:R:V94	R:R:Y333	5.05	No	Yes	1	7	7
43	R:R:P96	R:R:V95	3.53	No	No	0	9	7
44	R:R:F97	R:R:W107	5.01	Yes	Yes	1	4	7
45	R:R:F97	R:R:W109	9.02	Yes	Yes	1	4	5
46	R:R:F97	R:R:W117	5.01	Yes	Yes	1	4	6
47	R:R:G98	R:R:W117	4.22	No	Yes	0	6	6
48	R:R:V102	R:R:W330	4.9	No	Yes	0	5	6
49	R:R:L108	R:R:R104	7.29	No	No	0	4	4
50	R:R:W107	R:R:W109	12.18	Yes	Yes	1	7	5
51	R:R:C114	R:R:W107	6.53	No	Yes	1	9	7
52	R:R:W107	R:R:W117	11.25	Yes	Yes	1	7	6
53	R:R:C199	R:R:W107	10.45	No	Yes	1	9	7
54	R:R:L108	R:R:W109	6.83	No	Yes	0	4	5
55	R:R:C114	R:R:C199	7.28	No	No	1	9	9
56	R:R:E115	R:R:M178	4.06	No	No	0	6	4
57	R:R:E115	R:R:H180	6.15	No	No	0	6	5
58	R:R:L116	R:R:M178	4.24	No	No	0	4	4
59	L:L:?401	R:R:W117	4.63	Yes	Yes	1	0	6
60	L:L:?401	R:R:T118	3.6	Yes	No	0	0	6
61	R:R:F174	R:R:S119	11.89	Yes	No	0	5	6
62	R:R:I177	R:R:S119	7.74	No	No	0	6	6
63	R:R:F174	R:R:L120	3.65	Yes	No	0	5	5
64	R:R:D121	R:R:V125	4.38	Yes	No	1	7	6
65	R:R:D121	R:R:Y333	12.64	Yes	Yes	1	7	7
66	L:L:?401	R:R:D121	18.76	Yes	Yes	1	0	7
67	L:L:?401	R:R:V122	13.33	Yes	No	0	0	6
68	R:R:L123	R:R:S173	6.01	No	No	6	5	7
69	R:R:F174	R:R:L123	4.87	Yes	No	6	5	5
70	R:R:V125	R:R:W303	9.81	No	Yes	1	6	8
71	L:L:?401	R:R:V125	7.27	Yes	No	1	0	6
72	R:R:E130	R:R:T126	5.64	No	Yes	0	6	6
73	R:R:S169	R:R:T126	6.4	No	Yes	0	8	6
74	R:R:S215	R:R:T126	9.59	No	Yes	0	6	6
75	R:R:A127	R:R:W166	7.78	No	No	0	7	9
76	R:R:F299	R:R:I129	5.02	Yes	No	1	9	8
77	R:R:I129	R:R:W303	8.22	No	Yes	1	8	8
78	R:R:E130	R:R:V165	5.7	No	No	0	6	6
79	R:R:E130	R:R:I168	5.47	No	No	0	6	4
80	R:R:L132	R:R:N339	5.49	No	Yes	5	8	9
81	R:R:L132	R:R:Y343	7.03	No	No	0	8	9
82	R:R:C133	R:R:P219	3.77	No	No	0	6	9
83	R:R:C133	R:R:I222	6.55	No	No	0	6	6
84	R:R:A136	R:R:Y227	5.34	No	Yes	0	8	9
85	R:R:D138	R:R:Y149	10.34	Yes	Yes	4	9	7
86	R:R:D138	R:R:M153	4.16	Yes	No	4	9	6
87	R:R:R139	R:R:Y227	5.14	No	Yes	0	9	9
88	R:R:R139	R:R:Y343	5.14	No	No	0	9	9
89	R:R:T144	R:R:Y140	16.23	No	Yes	7	7	8
90	R:R:V226	R:R:Y140	8.83	No	Yes	0	6	8
91	R:R:R229	R:R:Y140	11.32	No	Yes	7	5	8
92	R:R:A142	R:R:Y149	9.34	No	Yes	0	8	7
93	R:R:I143	R:R:V230	4.61	No	No	0	9	9
94	R:R:R229	R:R:T144	6.47	No	No	7	5	7
95	R:R:L152	R:R:R148	4.86	No	No	0	5	5
96	R:R:M153	R:R:Y149	8.38	No	Yes	4	6	7
97	R:R:R157	R:R:T154	6.47	No	No	0	7	8
98	R:R:I214	R:R:V172	4.61	No	No	0	4	5
99	R:R:F174	R:R:S173	6.61	Yes	No	6	5	7
100	R:R:L175	R:R:P176	4.93	No	No	0	6	7
101	R:R:L175	R:R:W181	4.56	No	No	0	6	6
102	R:R:P176	R:R:Y207	4.17	No	Yes	0	7	7
103	R:R:I177	R:R:W182	12.92	No	Yes	3	6	5
104	R:R:I177	R:R:Y207	4.84	No	Yes	3	6	7
105	R:R:M179	R:R:W181	11.63	No	No	0	5	6
106	R:R:H180	R:R:R183	18.05	No	No	0	5	4
107	R:R:R183	R:R:W182	5	No	Yes	0	4	5
108	R:R:T203	R:R:W182	3.64	Yes	Yes	3	4	5
109	R:R:W182	R:R:Y207	6.75	Yes	Yes	3	5	7
110	R:R:R183	R:R:Y193	23.66	No	Yes	0	4	3
111	R:R:D184	R:R:D186	10.65	No	No	0	4	1
112	R:R:D184	R:R:N204	4.04	No	No	0	4	5
113	R:R:D186	R:R:P187	4.83	No	No	0	1	1
114	R:R:A189	R:R:Y193	5.34	No	Yes	0	4	3
115	R:R:C192	R:R:C198	3.64	No	No	0	4	5
116	R:R:D195	R:R:P196	6.44	No	No	0	3	3
117	R:R:C198	R:R:D195	4.67	No	No	0	5	3
118	R:R:F201	R:R:T203	3.89	No	Yes	0	4	4
119	R:R:F201	R:R:N310	4.83	No	No	0	4	6
120	L:L:?401	R:R:F201	21.79	Yes	No	0	0	4
121	R:R:R317	R:R:V202	5.23	No	No	0	1	4
122	R:R:T203	R:R:Y207	3.75	Yes	Yes	3	4	7
123	R:R:F315	R:R:R205	12.83	No	No	0	5	5
124	R:R:S211	R:R:Y207	7.63	No	Yes	0	6	7
125	R:R:A208	R:R:V314	5.09	No	No	0	6	5
126	L:L:?401	R:R:S211	9.77	Yes	No	0	0	6
127	R:R:F307	R:R:S212	3.96	Yes	No	0	7	6
128	R:R:I311	R:R:S212	6.19	No	No	0	5	6
129	L:L:?401	R:R:S215	4.88	Yes	No	0	0	6
130	R:R:F216	R:R:Y217	6.19	Yes	No	0	7	5
131	R:R:F216	R:R:L220	6.09	Yes	No	1	7	6
132	R:R:F216	R:R:F299	6.43	Yes	Yes	1	7	9
133	R:R:F216	R:R:L304	4.87	Yes	No	0	7	7
134	R:R:F216	R:R:F307	18.22	Yes	Yes	1	7	7
135	R:R:I311	R:R:Y217	4.84	No	No	0	5	5
136	R:R:I224	R:R:L220	4.28	No	No	0	5	6
137	R:R:F299	R:R:L220	3.65	Yes	No	1	9	6
138	R:R:M223	R:R:Y227	4.79	No	Yes	0	8	9
139	R:R:F299	R:R:M223	8.71	Yes	No	0	9	8
140	R:R:I295	R:R:Y227	4.84	No	Yes	0	8	9
141	R:R:M296	R:R:Y227	4.79	No	Yes	0	8	9
142	R:R:K235	R:R:Y231	9.55	No	No	0	5	6
143	R:R:E285	R:R:K235	13.5	No	No	0	7	5
144	R:R:E236	R:R:R239	4.65	No	No	0	4	5
145	R:R:K240	R:R:Q237	5.42	No	No	0	5	7
146	R:R:I238	R:R:R284	8.77	No	No	0	5	6
147	R:R:E285	R:R:I238	8.2	No	No	0	7	5
148	R:R:I241	R:R:R284	5.01	No	No	0	5	6
149	R:R:D242	R:R:R247	4.76	No	No	0	4	3
150	R:R:I294	R:R:K290	4.36	No	No	0	7	7
151	R:R:I342	R:R:V298	4.61	No	No	0	8	6
152	R:R:F299	R:R:W303	4.01	Yes	Yes	1	9	8
153	R:R:L304	R:R:T300	4.42	No	No	0	7	5
154	R:R:C302	R:R:N335	9.45	No	No	0	8	9
155	R:R:F306	R:R:W303	4.01	Yes	Yes	1	7	8
156	R:R:F307	R:R:W303	9.02	Yes	Yes	1	7	8
157	R:R:G332	R:R:W303	11.26	No	Yes	0	6	8
158	R:R:N335	R:R:W303	7.91	No	Yes	0	9	8
159	R:R:L304	R:R:L308	8.3	No	No	0	7	6
160	R:R:F328	R:R:P305	8.67	Yes	No	0	5	9
161	R:R:F306	R:R:F307	9.65	Yes	Yes	1	7	7
162	R:R:F306	R:R:F325	9.65	Yes	No	0	7	4
163	R:R:F306	R:R:N329	20.54	Yes	No	1	7	6
164	L:L:?401	R:R:F306	6.93	Yes	Yes	1	0	7
165	L:L:?401	R:R:F307	5.94	Yes	Yes	1	0	7
166	R:R:V309	R:R:V320	6.41	No	Yes	0	4	5
167	R:R:F325	R:R:V309	6.55	No	No	0	4	4
168	R:R:F328	R:R:V309	3.93	Yes	No	0	5	4
169	R:R:F325	R:R:N310	7.25	No	No	0	4	6
170	R:R:N313	R:R:R317	8.44	No	No	0	4	1
171	R:R:P321	R:R:V320	3.53	No	Yes	0	5	5
172	R:R:P321	R:R:W323	8.11	No	No	0	5	3
173	R:R:L324	R:R:W323	6.83	No	No	0	4	3
174	R:R:F328	R:R:L324	12.18	Yes	No	0	5	4
175	R:R:F327	R:R:F328	4.29	No	Yes	0	5	5
176	R:R:F327	R:R:L331	3.65	No	No	0	5	7
177	R:R:N329	R:R:Y333	10.47	No	Yes	1	6	7
178	L:L:?401	R:R:N329	15.63	Yes	No	1	0	6
179	R:R:W330	R:R:Y333	3.86	Yes	Yes	0	6	7
180	L:L:?401	R:R:Y333	5.72	Yes	Yes	1	0	7
181	R:R:N335	R:R:N339	4.09	No	Yes	0	9	9
182	R:R:I342	R:R:Y343	7.25	No	No	0	8	9
183	R:R:C344	R:R:F349	13.97	No	Yes	0	6	8
184	R:R:R345	R:R:R350	5.33	No	No	0	7	8
185	R:R:P347	R:R:S346	5.34	No	No	0	6	8
186	R:R:F349	R:R:F353	9.65	Yes	No	0	8	7
187	R:R:L356	R:R:R355	7.29	No	No	0	6	4
188	R:R:L292	R:R:Y227	3.52	No	Yes	0	8	9
189	R:R:L289	R:R:Y231	3.52	No	No	0	7	6
190	R:R:L292	R:R:Y231	3.52	No	No	0	8	6
191	R:R:N204	R:R:Y207	3.49	No	Yes	0	5	7
192	R:R:C124	R:R:V89	3.42	No	No	0	6	6
193	R:R:C124	R:R:V90	3.42	No	No	0	6	8
194	R:R:L101	R:R:W107	3.42	No	Yes	0	5	7
195	R:R:L113	R:R:W109	3.42	No	Yes	0	4	5
196	R:R:A84	R:R:V62	3.39	No	No	0	8	9
197	R:R:I129	R:R:P219	3.39	No	No	0	8	9
198	R:R:I218	R:R:P219	3.39	No	No	0	5	9
199	R:R:A208	R:R:T203	3.36	No	Yes	0	6	4
200	R:R:D195	R:R:G197	3.35	No	No	0	3	4
201	R:R:C85	R:R:I63	3.27	No	No	0	5	7
202	R:R:C133	R:R:I137	3.27	No	No	0	6	6
203	R:R:A84	R:R:I63	3.25	No	No	0	8	7
204	R:R:A99	R:R:M48	3.22	No	No	0	6	6
205	R:R:V52	R:R:V95	3.21	No	No	0	5	7
206	R:R:S145	R:R:T144	3.2	No	No	0	6	7
207	R:R:T126	R:R:V172	3.17	Yes	No	0	6	5
208	R:R:C198	R:R:D200	3.11	No	No	0	5	5
209	R:R:F225	R:R:Y140	3.09	No	Yes	0	5	8
210	R:R:I55	R:R:V51	3.07	Yes	No	0	7	6
211	R:R:I161	R:R:V134	3.07	No	No	0	6	5
212	R:R:L47	R:R:V51	2.98	No	No	0	5	6
213	R:R:L92	R:R:V56	2.98	No	No	0	5	6
214	R:R:L319	R:R:V320	2.98	No	Yes	0	6	5
215	R:R:I66	R:R:I80	2.94	Yes	No	0	7	7
216	R:R:I209	R:R:I213	2.94	No	No	0	5	4
217	R:R:I213	R:R:I218	2.94	No	No	0	4	5
218	R:R:G110	R:R:W107	2.81	No	Yes	0	7	7
219	R:R:C302	R:R:F338	2.79	No	No	0	8	6
220	R:R:A158	R:R:F79	2.77	No	Yes	0	7	8
221	R:R:L88	R:R:N59	2.75	No	No	0	7	9
222	R:R:L319	R:R:N316	2.75	No	No	0	6	4
223	R:R:E233	R:R:I143	2.73	No	No	0	6	9
224	R:R:D348	R:R:L72	2.71	No	No	0	6	8
225	R:R:C192	R:R:Y193	2.69	No	Yes	0	4	3
226	R:R:F349	R:R:S346	2.64	Yes	No	0	8	8
227	R:R:R205	R:R:V314	2.62	No	No	0	5	5
228	R:R:A86	R:R:W166	2.59	No	No	0	8	9
229	R:R:V202	R:R:Y193	2.52	No	Yes	0	4	3
230	R:R:V226	R:R:Y227	2.52	No	Yes	0	6	9
231	R:R:V95	R:R:W330	2.45	No	Yes	0	7	6
232	R:R:V326	R:R:W330	2.45	No	Yes	0	4	6
233	R:R:L141	R:R:Y149	2.34	No	Yes	0	5	7
234	R:R:A57	R:R:G58	1.95	No	No	0	4	8
235	R:R:G105	R:R:T106	1.82	No	No	0	4	3
236	R:R:A352	R:R:A65	1.79	No	No	0	7	7
237	R:R:P196	R:R:S111	1.78	No	No	0	3	4
238	R:R:P146	R:R:S145	1.78	No	No	0	8	6
239	R:R:G297	R:R:M296	1.75	No	No	0	5	8
240	R:R:G43	R:R:L46	1.71	No	No	0	4	4
241	R:R:A352	R:R:T69	1.68	No	No	0	7	6
242	R:R:A337	R:R:I55	1.62	No	Yes	0	6	7
243	R:R:V56	R:R:V60	1.6	No	No	0	6	3
244	R:R:V312	R:R:V320	1.6	No	Yes	0	5	5
245	R:R:T164	R:R:V160	1.59	No	No	0	3	3
246	R:R:A337	R:R:L54	1.58	No	No	0	6	5
247	R:R:A64	R:R:L356	1.58	No	No	0	4	6
248	R:R:A158	R:R:L78	1.58	No	No	0	7	5
249	R:R:A170	R:R:L123	1.58	No	No	0	3	5
250	R:R:P187	R:R:Q188	1.58	No	No	0	1	2
251	R:R:A206	R:R:N204	1.56	No	No	0	4	5
252	R:R:I294	R:R:V298	1.54	No	No	0	7	6
253	R:R:M44	R:R:V102	1.52	No	No	0	4	5
254	R:R:I168	R:R:T164	1.52	No	No	0	4	3
255	R:R:I295	R:R:T291	1.52	No	No	0	8	8
256	R:R:K287	R:R:T291	1.5	No	No	0	8	8
257	R:R:L108	R:R:T106	1.47	No	No	0	4	3
258	R:R:I224	R:R:L228	1.43	No	No	0	5	2
259	R:R:L141	R:R:L152	1.38	No	No	0	5	5
260	R:R:L171	R:R:L175	1.38	No	No	0	4	6
261	R:R:L190	R:R:Q194	1.33	No	No	0	1	3
262	R:R:F97	R:R:T100	1.3	Yes	No	0	4	4
263	R:R:D184	R:R:E185	1.3	No	No	0	4	2
264	R:R:E233	R:R:E236	1.27	No	No	0	6	4
265	R:R:I341	R:R:R345	1.25	No	No	0	6	7
266	R:R:F353	R:R:L61	1.22	No	No	0	7	6
267	R:R:E233	R:R:R229	1.16	No	No	0	6	5
268	R:R:F248	R:R:R247	1.07	No	No	0	3	3

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:I55	4.3775	4	0	7
2	R:R:I66	5.9625	4	2	7
3	R:R:N77	7.9325	4	2	9
4	R:R:F79	5.558	5	0	8
5	R:R:D87	7.7825	4	0	9
6	R:R:F97	5.085	4	1	4
7	R:R:W107	7.37857	7	1	7
8	R:R:W109	7.8625	4	1	5
9	R:R:W117	6.2775	4	1	6
10	R:R:D121	11.5	4	1	7
11	R:R:T126	6.2	4	0	6
12	R:R:D138	6.8	4	4	9
13	R:R:Y140	9.8675	4	7	8
14	R:R:Y149	7.6	4	4	7
15	R:R:F174	6.755	4	6	5
16	R:R:W182	7.0775	4	3	5
17	R:R:Y193	8.5525	4	0	3
18	R:R:T203	3.66	4	3	4
19	R:R:Y207	5.105	6	3	7
20	R:R:F216	8.36	5	1	7
21	R:R:Y227	4.42	7	0	9
22	R:R:F299	5.564	5	1	9
23	R:R:W303	7.74857	7	1	8
24	R:R:F306	10.156	5	1	7
25	R:R:F307	9.358	5	1	7
26	R:R:V320	3.63	4	0	5
27	R:R:F328	7.2675	4	0	5
28	R:R:W330	6.92	5	0	6
29	R:R:Y333	7.548	5	1	7
30	R:R:N339	5.795	4	5	9
31	R:R:F349	7.84333	6	2	8
32	L:L:?401	9.85417	12	1	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:D87	R:R:S336	17.4321	10.31	Yes	No	0	9	9
2	R:R:D87	R:R:N339	67.5068	6.73	Yes	Yes	0	9	9
3	R:R:N335	R:R:N339	96.6675	4.09	No	Yes	0	9	9
4	R:R:N335	R:R:W303	100	7.91	No	Yes	0	9	8
5	R:R:V125	R:R:W303	46.3655	9.81	No	Yes	1	6	8
6	R:R:W330	R:R:Y333	21.8852	3.86	Yes	Yes	0	6	7
7	L:L:?401	R:R:V125	41.75	7.27	Yes	No	1	0	6
8	L:L:?401	R:R:Y333	16.6104	5.72	Yes	Yes	1	0	7
9	R:R:F306	R:R:W303	51.8709	4.01	Yes	Yes	1	7	8
10	L:L:?401	R:R:F306	44.8649	6.93	Yes	Yes	1	0	7
11	R:R:F307	R:R:W303	43.6404	9.02	Yes	Yes	1	7	8
12	L:L:?401	R:R:F307	55.6516	5.94	Yes	Yes	1	0	7
13	R:R:N59	R:R:P340	42.6595	4.89	No	No	0	9	9
14	R:R:D87	R:R:N59	49.7726	6.73	Yes	No	0	9	9
15	R:R:P340	R:R:V62	38.3136	3.53	No	No	0	9	9
16	R:R:C344	R:R:V62	32.4282	6.83	No	No	0	6	9
17	R:R:A65	R:R:F353	11.1829	4.16	No	No	0	7	7
18	R:R:F349	R:R:F353	14.3075	9.65	Yes	No	0	8	7
19	R:R:C344	R:R:F349	30.9406	13.97	No	Yes	0	6	8
20	R:R:D138	R:R:F79	13.8073	8.36	Yes	Yes	0	9	8
21	R:R:F79	R:R:I162	24.6492	5.02	Yes	No	0	8	7
22	R:R:I162	R:R:S82	26.166	4.64	No	No	0	7	9
23	R:R:S82	R:R:T131	32.1684	7.99	No	No	0	9	8
24	R:R:L83	R:R:T131	33.6527	5.9	No	No	0	9	8
25	R:R:L83	R:R:N339	32.5679	6.87	No	Yes	5	9	9
26	R:R:L132	R:R:N339	12.625	5.49	No	Yes	5	8	9
27	R:R:F174	R:R:S119	10.4814	11.89	Yes	No	0	5	6
28	R:R:I177	R:R:S119	12.0534	7.74	No	No	0	6	6
29	R:R:I177	R:R:Y207	12.6283	4.84	No	Yes	3	6	7
30	R:R:S211	R:R:Y207	57.2983	7.63	No	Yes	0	6	7
31	L:L:?401	R:R:S211	58.6625	9.77	Yes	No	0	0	6
32	R:R:F97	R:R:W117	13.1967	5.01	Yes	Yes	1	4	6
33	L:L:?401	R:R:W117	34.075	4.63	Yes	Yes	1	0	6
34	R:R:W107	R:R:W117	18.0005	11.25	Yes	Yes	1	7	6
35	R:R:L108	R:R:W109	13.3136	6.83	No	Yes	0	4	5
36	R:R:H180	R:R:R183	12.0956	18.05	No	No	0	5	4
37	R:R:R183	R:R:W182	51.4714	5	No	Yes	0	4	5
38	R:R:T203	R:R:W182	27.8128	3.64	Yes	Yes	3	4	5
39	R:R:F201	R:R:T203	36.0108	3.89	No	Yes	0	4	4
40	L:L:?401	R:R:F201	34.8155	21.79	Yes	No	0	0	4
41	R:R:W182	R:R:Y207	26.7344	6.75	Yes	Yes	3	5	7
42	R:R:S215	R:R:T126	15.139	9.59	No	Yes	0	6	6
43	L:L:?401	R:R:S215	16.789	4.88	Yes	No	0	0	6
44	R:R:F216	R:R:F299	12.5276	6.43	Yes	Yes	1	7	9
45	R:R:F216	R:R:F307	15.1553	18.22	Yes	Yes	1	7	7
46	R:R:F299	R:R:W303	37.8914	4.01	Yes	Yes	1	9	8
47	R:R:I129	R:R:W303	11.6377	8.22	No	Yes	1	8	8
48	R:R:L132	R:R:Y343	13.7619	7.03	No	No	0	8	9
49	R:R:I129	R:R:P219	11.2057	3.39	No	No	0	8	9
50	R:R:M223	R:R:Y227	44.8681	4.79	No	Yes	0	8	9
51	R:R:F299	R:R:M223	46.3265	8.71	Yes	No	0	9	8
52	R:R:V226	R:R:Y227	23.0707	2.52	No	Yes	0	6	9
53	R:R:V226	R:R:Y140	21.1836	8.83	No	Yes	0	6	8
54	R:R:R229	R:R:Y140	11.5857	11.32	No	Yes	7	5	8
55	R:R:R183	R:R:Y193	36.6669	23.66	No	Yes	0	4	3
56	R:R:N204	R:R:Y207	11.7286	3.49	No	Yes	0	5	7
57	R:R:C192	R:R:Y193	21.5961	2.69	No	Yes	0	4	3
58	R:R:C192	R:R:C198	18.5299	3.64	No	No	0	4	5
59	R:R:C198	R:R:D195	12.3782	4.67	No	No	0	5	3
60	R:R:L292	R:R:Y231	13.1187	3.52	No	No	0	8	6
61	R:R:L292	R:R:Y227	14.8142	3.52	No	Yes	0	8	9
62	R:R:F325	R:R:V309	11.4817	6.55	No	No	0	4	4
63	R:R:F306	R:R:F325	10.3027	9.65	Yes	No	0	7	4

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:D121	R:R:V94	10.22	1	Yes	No	7	7	1	2
R:R:V94	R:R:Y333	5.05	1	No	Yes	7	7	2	1
R:R:F97	R:R:W107	5.01	1	Yes	Yes	4	7	2	2
R:R:F97	R:R:W117	5.01	1	Yes	Yes	4	6	2	1
R:R:G98	R:R:W117	4.22	0	No	Yes	6	6	2	1
R:R:W107	R:R:W117	11.25	1	Yes	Yes	7	6	2	1
L:L:?401	R:R:W117	4.63	1	Yes	Yes	0	6	0	1
L:L:?401	R:R:T118	3.6	1	Yes	No	0	6	0	1
R:R:D121	R:R:V125	4.38	1	Yes	No	7	6	1	1
R:R:D121	R:R:Y333	12.64	1	Yes	Yes	7	7	1	1
L:L:?401	R:R:D121	18.76	1	Yes	Yes	0	7	0	1
L:L:?401	R:R:V122	13.33	1	Yes	No	0	6	0	1
R:R:V125	R:R:W303	9.81	1	No	Yes	6	8	1	2
L:L:?401	R:R:V125	7.27	1	Yes	No	0	6	0	1
R:R:S215	R:R:T126	9.59	0	No	Yes	6	6	1	2
R:R:F201	R:R:T203	3.89	0	No	Yes	4	4	1	2
R:R:F201	R:R:N310	4.83	0	No	No	4	6	1	2
L:L:?401	R:R:F201	21.79	1	Yes	No	0	4	0	1
R:R:T203	R:R:Y207	3.75	3	Yes	Yes	4	7	2	2
R:R:S211	R:R:Y207	7.63	0	No	Yes	6	7	1	2
L:L:?401	R:R:S211	9.77	1	Yes	No	0	6	0	1
R:R:F307	R:R:S212	3.96	1	Yes	No	7	6	1	2
L:L:?401	R:R:S215	4.88	1	Yes	No	0	6	0	1
R:R:F216	R:R:F307	18.22	1	Yes	Yes	7	7	2	1
R:R:F306	R:R:W303	4.01	1	Yes	Yes	7	8	1	2
R:R:F307	R:R:W303	9.02	1	Yes	Yes	7	8	1	2
R:R:F306	R:R:F307	9.65	1	Yes	Yes	7	7	1	1
R:R:F306	R:R:F325	9.65	1	Yes	No	7	4	1	2
R:R:F306	R:R:N329	20.54	1	Yes	No	7	6	1	1
L:L:?401	R:R:F306	6.93	1	Yes	Yes	0	7	0	1
L:L:?401	R:R:F307	5.94	1	Yes	Yes	0	7	0	1
R:R:F325	R:R:N310	7.25	0	No	No	4	6	2	2
R:R:N329	R:R:Y333	10.47	1	No	Yes	6	7	1	1
L:L:?401	R:R:N329	15.63	1	Yes	No	0	6	0	1
R:R:W330	R:R:Y333	3.86	0	Yes	Yes	6	7	2	1
L:L:?401	R:R:Y333	5.72	1	Yes	Yes	0	7	0	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	7JJO_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.53
Number of Linked Nodes	248
Number of Links	268
Number of Hubs	32
Number of Links mediated by Hubs	129
Number of Communities	7
Number of Nodes involved in Communities	39
Number of Links involved in Communities	54

Path Summary
Number Of Nodes in MetaPath	64
Number Of Links MetaPath	63
Number of Shortest Paths	63550
Length Of Smallest Path	3
Average Path Length	12.97
Length of Longest Path	28
Minimum Path Strength	1.215
Average Path Strength	6.79854
Maximum Path Strength	20.855
Minimum Path Correlation	0.7
Average Path Correlation	0.919369
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	5.55556
Average % Of Corr. Nodes	48.4907
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	45.3022
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process	• cellular response to stimulus • positive regulation of cell communication • regulation of cellular process • positive regulation of signal transduction • response to stimulus • signaling • positive regulation of biological process • regulation of signal transduction • intracellular signal transduction • cell communication • positive regulation of response to stimulus • regulation of intracellular signal transduction • intracellular signaling cassette • signal transduction • positive regulation of cellular process • regulation of biological process • regulation of signaling • positive regulation of MAPK cascade • biological regulation • positive regulation of intracellular signal transduction • regulation of MAPK cascade • regulation of response to stimulus • MAPK cascade • regulation of cell communication • cellular process • positive regulation of signaling • adenylate cyclase-activating adrenergic receptor signaling pathway • adenylate cyclase-activating G protein-coupled receptor signaling pathway • adrenergic receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • rhythmic process • circadian sleep/wake cycle, sleep • multicellular organismal process • circadian sleep/wake cycle • rhythmic behavior • regulation of circadian sleep/wake cycle • circadian rhythm • regulation of circadian rhythm • regulation of behavior • behavior • circadian behavior • regulation of multicellular organismal process • sleep • regulation of circadian sleep/wake cycle, sleep • circadian sleep/wake cycle process • regulation of tube diameter • regulation of systemic arterial blood pressure mediated by a chemical signal • system process • regulation of blood pressure • regulation of tube size • norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure • negative regulation of blood pressure • regulation of systemic arterial blood pressure by norepinephrine-epinephrine • regulation of systemic arterial blood pressure • circulatory system process • negative regulation of systemic arterial blood pressure • vascular process in circulatory system • regulation of biological quality • blood vessel diameter maintenance • vasodilation • blood circulation • regulation of anatomical structure size • heart process • regulation of heart contraction • regulation of system process • positive regulation of blood circulation • positive regulation of heart contraction • regulation of blood circulation • positive regulation of multicellular organismal process • heart contraction • membrane-bounded organelle • intracellular anatomical structure • early endosome • endosome • intracellular vesicle • intracellular membrane-bounded organelle • endomembrane system • intracellular organelle • cellular anatomical structure • cytoplasmic vesicle • organelle • cytoplasm • vesicle • membrane
Gene Ontology	Cellular Component	• membrane-bounded organelle • intracellular anatomical structure • early endosome • endosome • intracellular vesicle • intracellular membrane-bounded organelle • endomembrane system • intracellular organelle • cellular anatomical structure • cytoplasmic vesicle • organelle • cytoplasm • vesicle • membrane • cell periphery • plasma membrane • protein binding • binding • G-protein beta-subunit binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • cellular response to nitrogen compound • cellular response to stimulus • response to dopamine • regulation of cellular process • response to stimulus • signaling • cellular response to dopamine • response to monoamine • cell communication • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • signal transduction • regulation of biological process • G protein-coupled dopamine receptor signaling pathway • biological regulation • response to oxygen-containing compound • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to monoamine stimulus • response to chemical • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • cellular process • G protein-coupled receptor signaling pathway • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • response to hormone • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • peptide hormone receptor binding • corticotropin-releasing hormone receptor binding • signaling receptor binding • G protein-coupled receptor binding • corticotropin-releasing hormone receptor 1 binding • hormone receptor binding • neuropeptide receptor binding • mu-type opioid receptor binding • opioid receptor binding • beta-2 adrenergic receptor binding • adrenergic receptor binding • D1 dopamine receptor binding • dopamine receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • ionotropic glutamate receptor binding • glutamate receptor binding • enzyme regulator activity • cyclase regulator activity • enzyme activator activity • cyclase activator activity • molecular function activator activity • molecular function regulator activity • adenylate cyclase regulator activity • adenylate cyclase activator activity • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • cation binding • metal ion binding • insulin-like growth factor receptor binding • adenylate cyclase-activating adrenergic receptor signaling pathway • adrenergic receptor signaling pathway • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • enzyme binding • GTPase binding • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • phospholipase C-activating G protein-coupled receptor signaling pathway • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection • photoreceptor cell cilium • organelle membrane • synapse • cell junction
SCOP2	Domain Identifier	• G protein-coupled receptor-like • Transducin (heterotrimeric G protein), gamma chain • Ras-like P-loop GTPases • WD40 repeat-like
SCOP2	Family Identifier	• G protein-coupled receptor-like • Transducin (heterotrimeric G protein), gamma chain • Ras-like P-loop GTPases • WD40 repeat-like
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	5FW
PDB Residues	L:L:?401
Environment Details	Open EMBL-EBI Page
Code	5FW
Name	ISOPRENALINE
Synonyms
Identifier
Formula	C11 H17 N O3
Molecular Weight	211.258
SMILES
PubChem	443372
Formal Charge	0
Total Atoms	32
Total Chiral Atoms	1
Total Bonds	32
Total Aromatic Bonds	6


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P07700
Sequence	>7JJO_nogp_Chain_R W E A G M S L L M A L V V L L I V A G N V L V I A A I G S T Q R L Q T L T N L F I T S L A C A D L V V G L L V V P F G A T L V V R G T W L W G S F L C E L W T S L D V L C V T A S I E T L C V I A I D R Y L A I T S P F R Y Q S L M T R A R A K V I I C T V W A I S A L V S F L P I M M H W W R D E D P Q A L K C Y Q D P G C C D F V T N R A Y A I A S S I I S F Y I P L L I M I F V Y L R V Y R E A K E Q I R K I D R F R E H K A L K T L G I I M G V F T L C W L P F F L V N I V N V F N R D L V P D W L F V F F N W L G Y A N S A F N P I I Y C R S P D F R K A F K R L L M G D G W L P P D C G P H N R S G G G G A T A A P T G S R Q V S A E L L S Q Q R M C R C E G Y G S Q E Q P Q P P P L P Q H Q P I L G N G R A S K R K T S R V M A M C F P R K A D R R L H A G G Q P A P L P G G F I S T L G S P E H S P G G T W S D C N G G T R G G S E S S L E E R H S K T S R S E S K M E R E K N I L A T T R F Y C T F L G N G D K A V F C T V L R I V K L F E D A T C T C P H T H K L K M K W R F K Q H Q A Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	3ZPQ	A	Amine	Adrenergic	β₁	Meleagris gallopavo	4-(piperazin-1- yl)-1H-indole	Na	-	2.8	2013-04-03	doi.org/10.1021/jm400140q
	3ZPR	A	Amine	Adrenergic	β₁	Meleagris gallopavo	4-methyl-2-(piperazin-1-yl)	Na	-	2.7	2013-04-03	doi.org/10.1021/jm400140q
	5A8E	A	Amine	Adrenergic	β₁	Meleagris gallopavo	7-Methylcyanopindolol	Na	-	2.4	2015-09-30	doi.org/10.1124/mol.115.101030
	4BVN	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Cyanopindolol	Na	-	2.1	2014-04-02	doi.org/10.1371/journal.pone.0092727
	7JJO	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Isoprenaline	-	Gs/β1/γ2	2.6	2020-09-02	doi.org/10.1016/j.molcel.2020.08.001
	7JJO (No Gprot)	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Isoprenaline	-		2.6	2020-09-02	doi.org/10.1016/j.molcel.2020.08.001
	4AMI	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Bucindolol	-	-	3.2	2012-05-23	doi.org/10.1016/j.str.2012.03.014
	4AMJ	A	Amine	Adrenergic	β₁	Meleagris gallopavo	S-Carvedilol	-	-	2.3	2012-05-23	doi.org/10.1016/j.str.2012.03.014
	2VT4	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Cyanopindolol	-	-	2.7	2008-06-24	doi.org/10.1038/nature07101
	2Y00	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Dobutamine	-	-	2.5	2011-01-12	doi.org/10.1038/nature09746
	2Y02	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Carmoterol	-	-	2.6	2011-01-12	doi.org/10.1038/nature09746
	2Y03	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Isoprenaline	-	-	2.85	2011-01-12	doi.org/10.1038/nature09746
	2Y04	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Salbutamol	-	-	3.05	2011-01-12	doi.org/10.1038/nature09746
	2Y01	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Dobutamine	-	-	2.6	2011-03-30	doi.org/10.1038/nature09746
	4GPO	A	Amine	Adrenergic	β₁	Meleagris gallopavo	-	-	-	3.5	2013-02-27	doi.org/10.1038/nsmb.2504
	5F8U	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Cyanopindolol	-	-	3.35	2015-12-23	doi.org/10.1038/nsmb.3130
	7BTS	A	Amine	Adrenergic	β₁	Homo sapiens	L-Epinephrine	-	-	3.13	2020-12-02	doi.org/10.1038/s41422-020-00424-2
	7BU6	A	Amine	Adrenergic	β₁	Homo sapiens	L-Norepinephrine	-	-	2.7	2020-12-02	doi.org/10.1038/s41422-020-00424-2
	7BU7	A	Amine	Adrenergic	β₁	Homo sapiens	BI167107	-	-	2.6	2020-12-02	doi.org/10.1038/s41422-020-00424-2
	7BVQ	A	Amine	Adrenergic	β₁	Homo sapiens	S-Carazolol	-	-	2.5	2020-12-02	doi.org/10.1038/s41422-020-00424-2
	8DCR	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Dobutamine	-	Gs/β1/γ2	2.6	2022-07-27	doi.org/10.1038/s41467-022-31823-1
	8DCR (No Gprot)	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Dobutamine	-		2.6	2022-07-27	doi.org/10.1038/s41467-022-31823-1
	8DCS	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Cyanopindolol	-	Gs/β1/γ2	2.5	2022-07-27	doi.org/10.1038/s41467-022-31823-1
	8DCS (No Gprot)	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Cyanopindolol	-		2.5	2022-07-27	doi.org/10.1038/s41467-022-31823-1
	6IBL	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Arformoterol	-	-	2.7	2019-01-09	doi.org/10.1038/s41586-020-2419-1
	6TKO	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Arformoterol	-	Arrestin2	3.3	2020-06-17	doi.org/10.1038/s41586-020-2419-1
	7S0F	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Isoprenaline	-	Gi1/β1/γ2	2.96	2021-11-17	doi.org/10.1038/s41594-021-00679-2
	7S0F (No Gprot)	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Isoprenaline	-		2.96	2021-11-17	doi.org/10.1038/s41594-021-00679-2
	7S0G	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Isoprenaline	-	chim(Gi1-CtGs)/β1/γ2	3.86	2021-11-17	doi.org/10.1038/s41594-021-00679-2
	7S0G (No Gprot)	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Isoprenaline	-		3.86	2021-11-17	doi.org/10.1038/s41594-021-00679-2
	2YCW	A	Amine	Adrenergic	β₁	Meleagris gallopavo	S-Carazolol	-	-	3	2011-06-01	doi.org/10.1073/pnas.1100185108
	2YCX	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Cyanopindolol	-	-	3.25	2011-06-01	doi.org/10.1073/pnas.1100185108
	2YCZ	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Iodocyanopindolol	-	-	3.65	2011-06-01	doi.org/10.1073/pnas.1100185108
	2YCY	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Cyanopindolol	-	-	3.15	2011-06-08	doi.org/10.1073/pnas.1100185108
	6H7N	A	Amine	Adrenergic	β₁	Meleagris gallopavo	S-Xamoterol	-	-	2.5	2018-10-17	doi.org/10.1101/436212
	6H7J	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Isoprenaline	-	-	2.8	2018-10-17	doi.org/10.1126/science.aau5595
	6H7L	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Dobutamine	-	-	2.7	2018-10-17	doi.org/10.1126/science.aau5595
	6H7M	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Salbutamol	-	-	2.76	2018-10-17	doi.org/10.1126/science.aau5595
	6H7O	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Cyanopindolol	-	-	2.8	2018-10-17	doi.org/10.1126/science.aau5595
	8S2T	A	Amine	Adrenergic	β₁	Homo sapiens	Isoprenaline	-	chim(NtGi1-Gs)/β1/γ2	3.3	2025-05-21	To be published
	8S2T (No Gprot)	A	Amine	Adrenergic	β₁	Homo sapiens	Isoprenaline	-		3.3	2025-05-21	To be published

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