psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:F25	R:R:N23	8.46	Yes	Yes	1	6	8
2	R:R:N23	R:R:V26	5.91	Yes	No	0	8	1
3	R:R:N23	R:R:N96	4.09	Yes	Yes	1	8	4
4	R:R:N23	R:R:R177	14.46	Yes	No	1	8	2
5	R:R:F25	R:R:Q24	14.05	Yes	No	0	6	3
6	R:R:K281	R:R:Q24	8.14	No	No	0	2	3
7	R:R:F25	R:R:N96	8.46	Yes	Yes	1	6	4
8	R:R:F25	R:R:Q284	9.37	Yes	No	0	6	4
9	L:L:F7	R:R:F25	16.08	No	Yes	1	0	6
10	R:R:H95	R:R:V26	6.92	No	No	0	5	1
11	R:R:Q27	R:R:Q31	7.68	Yes	No	2	4	2
12	R:R:I32	R:R:Q27	8.23	No	Yes	2	3	4
13	R:R:Q27	R:R:V94	4.3	Yes	Yes	2	4	5
14	R:R:Q27	R:R:Q284	10.24	Yes	No	0	4	4
15	R:R:P28	R:R:W30	9.46	No	No	2	2	1
16	R:R:P28	R:R:Q31	14.21	No	No	2	2	2
17	R:R:Q31	R:R:W30	14.24	No	No	2	2	1
18	R:R:I32	R:R:V94	6.14	No	Yes	2	3	5
19	R:R:Q285	R:R:W35	6.57	No	No	0	1	4
20	R:R:L288	R:R:W35	18.22	No	No	0	3	4
21	R:R:F90	R:R:Y39	16.5	No	No	0	6	7
22	R:R:L288	R:R:Y39	4.69	No	No	0	3	7
23	R:R:W292	R:R:Y39	6.75	Yes	No	0	5	7
24	R:R:I42	R:R:W292	17.62	No	Yes	0	7	5
25	R:R:V43	R:R:V87	4.81	No	No	0	6	8
26	R:R:M299	R:R:T45	7.53	No	No	0	7	4
27	R:R:N50	R:R:S46	4.47	Yes	No	0	9	8
28	R:R:S46	R:R:T298	7.99	No	No	0	8	9
29	R:R:G49	R:R:P302	4.06	No	No	0	8	9
30	R:R:E78	R:R:N50	7.89	Yes	Yes	0	9	9
31	R:R:A79	R:R:N50	4.69	No	Yes	0	7	9
32	R:R:N50	R:R:P302	8.15	Yes	No	0	9	9
33	R:R:F316	R:R:V52	14.42	No	No	0	6	6
34	R:R:F312	R:R:V53	6.55	Yes	No	0	9	8
35	R:R:A59	R:R:W55	10.37	No	Yes	3	4	4
36	R:R:H60	R:R:W55	6.35	Yes	Yes	3	5	4
37	R:R:H318	R:R:W55	5.29	No	Yes	3	3	4
38	R:R:H60	R:R:I56	5.3	Yes	Yes	3	5	8
39	R:R:I56	R:R:M63	4.37	Yes	No	3	8	7
40	R:R:F312	R:R:I56	6.28	Yes	Yes	0	9	8
41	R:R:I57	R:R:N68	7.08	No	No	0	7	8
42	R:R:L58	R:R:R64	8.5	No	No	0	2	6
43	R:R:A59	R:R:H60	7.32	No	Yes	3	4	5
44	R:R:H60	R:R:M63	5.25	Yes	No	3	5	7
45	R:R:H318	R:R:H60	5.97	No	Yes	3	3	5
46	R:R:R311	R:R:R62	5.33	No	No	0	6	5
47	R:R:T65	R:R:T67	4.71	No	No	0	7	8
48	R:R:N68	R:R:T65	5.85	No	No	0	8	7
49	R:R:V66	R:R:Y69	6.31	Yes	No	5	6	5
50	R:R:R141	R:R:V66	10.46	Yes	Yes	5	5	6
51	R:R:T147	R:R:V66	4.76	Yes	Yes	5	7	6
52	R:R:T147	R:R:Y69	4.99	Yes	No	5	7	5
53	R:R:K148	R:R:Y69	8.36	No	No	0	2	5
54	R:R:A125	R:R:F70	8.32	No	Yes	0	7	7
55	R:R:D129	R:R:F70	8.36	No	Yes	0	9	7
56	R:R:F70	R:R:T147	5.19	Yes	Yes	0	7	7
57	R:R:F70	R:R:V150	6.55	Yes	No	0	7	5
58	R:R:L71	R:R:Y305	10.55	No	No	0	8	9
59	R:R:N73	R:R:S122	5.96	No	No	0	9	8
60	R:R:I151	R:R:N73	14.16	No	No	0	8	9
61	R:R:N73	R:R:W155	7.91	No	Yes	0	9	9
62	R:R:E78	R:R:L74	6.63	Yes	No	6	9	9
63	R:R:L74	R:R:S122	4.5	No	No	0	9	8
64	R:R:L74	R:R:N301	8.24	No	No	6	9	9
65	R:R:F76	R:R:S80	7.93	No	No	0	6	6
66	R:R:E78	R:R:T298	9.88	Yes	No	0	9	9
67	R:R:E78	R:R:N301	11.83	Yes	No	6	9	9
68	R:R:M81	R:R:V116	4.56	Yes	No	0	7	7
69	R:R:M81	R:R:S119	4.6	Yes	No	0	7	9
70	R:R:M295	R:R:M81	4.33	Yes	Yes	0	7	7
71	R:R:M81	R:R:T298	4.52	Yes	No	0	7	9
72	R:R:F107	R:R:F84	5.36	Yes	No	1	4	5
73	R:R:F111	R:R:F84	5.36	Yes	No	1	4	5
74	R:R:N85	R:R:N89	5.45	Yes	Yes	1	6	6
75	R:R:H108	R:R:N85	8.93	Yes	Yes	1	5	6
76	R:R:N85	R:R:P112	4.89	Yes	Yes	1	6	6
77	R:R:M291	R:R:N85	4.21	Yes	Yes	1	5	6
78	R:R:M295	R:R:N85	4.21	Yes	Yes	1	7	6
79	L:L:?12	R:R:N85	10.2	No	Yes	1	0	6
80	R:R:M295	R:R:T86	9.03	Yes	No	0	7	7
81	R:R:V88	R:R:Y100	15.14	No	Yes	1	5	7
82	R:R:V88	R:R:Y104	6.31	No	No	1	5	5
83	R:R:H108	R:R:V88	12.45	Yes	No	1	5	5
84	R:R:H108	R:R:N89	12.75	Yes	Yes	1	5	6
85	R:R:N89	R:R:Y287	8.14	Yes	Yes	1	6	5
86	R:R:M291	R:R:N89	5.61	Yes	Yes	1	5	6
87	L:L:L10	R:R:N89	6.87	Yes	Yes	1	0	6
88	R:R:F90	R:R:V94	7.87	No	Yes	0	6	5
89	R:R:T91	R:R:Y100	6.24	No	Yes	0	4	7
90	R:R:N96	R:R:Y92	6.98	Yes	Yes	1	4	4
91	R:R:W98	R:R:Y92	11.58	Yes	Yes	1	8	4
92	R:R:V179	R:R:Y92	6.31	No	Yes	1	3	4
93	L:L:F8	R:R:Y92	4.13	Yes	Yes	1	0	4
94	L:L:L10	R:R:Y92	5.86	Yes	Yes	1	0	4
95	R:R:H95	R:R:V94	8.3	No	Yes	0	5	5
96	R:R:E97	R:R:H95	6.15	No	No	0	4	5
97	R:R:N96	R:R:R177	13.26	Yes	No	1	4	2
98	R:R:N96	R:R:V179	4.43	Yes	No	1	4	3
99	L:L:F7	R:R:N96	8.46	No	Yes	1	0	4
100	L:L:F8	R:R:N96	6.04	Yes	Yes	1	0	4
101	R:R:E97	R:R:Y99	17.96	No	No	0	4	2
102	R:R:W98	R:R:Y100	15.43	Yes	Yes	1	8	7
103	R:R:C105	R:R:W98	5.22	No	Yes	1	9	8
104	R:R:H108	R:R:W98	4.23	Yes	Yes	1	5	8
105	R:R:C180	R:R:W98	10.45	No	Yes	1	9	8
106	R:R:Y100	R:R:Y104	11.91	Yes	No	1	7	5
107	R:R:K106	R:R:L102	5.64	No	No	0	6	3
108	R:R:L102	R:R:T171	11.79	No	No	0	3	5
109	R:R:F107	R:R:Y104	11.35	Yes	No	1	4	5
110	R:R:C105	R:R:C180	7.28	No	No	1	9	9
111	R:R:K106	R:R:S169	9.18	No	No	0	6	5
112	R:R:F107	R:R:F111	7.5	Yes	Yes	1	4	4
113	R:R:F107	R:R:P112	4.33	Yes	Yes	1	4	6
114	R:R:H108	R:R:P112	10.68	Yes	Yes	1	5	6
115	L:L:L10	R:R:H108	5.14	Yes	Yes	1	0	5
116	L:L:?12	R:R:H108	6.36	No	Yes	1	0	5
117	R:R:I113	R:R:N109	4.25	Yes	No	0	5	5
118	R:R:N109	R:R:S169	5.96	No	No	0	5	5
119	L:L:L10	R:R:N109	8.24	Yes	No	0	0	5
120	R:R:F110	R:R:L159	7.31	No	No	0	6	4
121	R:R:F111	R:R:P112	5.78	Yes	Yes	1	4	6
122	R:R:F111	R:R:W155	5.01	Yes	Yes	0	4	9
123	R:R:F117	R:R:I113	5.02	No	Yes	0	7	5
124	R:R:I113	R:R:Q165	5.49	Yes	Yes	1	5	6
125	L:L:M11	R:R:I113	4.37	Yes	Yes	1	0	5
126	L:L:?12	R:R:I113	10.6	No	Yes	1	0	5
127	R:R:V116	R:R:W261	4.9	No	Yes	0	7	8
128	R:R:F117	R:R:L161	12.18	No	No	0	7	5
129	R:R:F117	R:R:I204	11.3	No	No	0	7	6
130	R:R:A118	R:R:W155	9.08	No	Yes	0	7	9
131	R:R:F257	R:R:I120	7.54	No	No	1	9	7
132	R:R:I120	R:R:W261	9.4	No	Yes	1	7	8
133	R:R:T124	R:R:V211	6.35	No	No	0	7	6
134	R:R:I212	R:R:T124	6.08	No	No	0	8	7
135	R:R:A127	R:R:Y216	5.34	No	Yes	0	9	9
136	R:R:F128	R:R:M132	8.71	No	No	0	5	5
137	R:R:F128	R:R:L142	4.87	No	No	0	5	6
138	R:R:D129	R:R:R141	10.72	No	Yes	0	9	5
139	R:R:R130	R:R:Y216	7.2	No	Yes	0	9	9
140	R:R:I135	R:R:Y131	13.3	Yes	Yes	4	7	8
141	R:R:H136	R:R:Y131	4.36	Yes	Yes	4	6	8
142	R:R:Y131	R:R:Y214	4.96	Yes	No	4	8	4
143	R:R:V218	R:R:Y131	8.83	No	Yes	4	4	8
144	R:R:H136	R:R:M132	5.25	Yes	No	0	6	5
145	R:R:I134	R:R:V219	12.29	No	No	0	8	8
146	R:R:I134	R:R:L223	4.28	No	No	0	8	8
147	R:R:H136	R:R:I135	10.61	Yes	Yes	4	6	7
148	R:R:I135	R:R:V218	4.61	Yes	No	4	7	4
149	R:R:I135	R:R:T222	4.56	Yes	No	0	7	5
150	R:R:R141	R:R:T147	9.06	Yes	Yes	5	5	7
151	R:R:L161	R:R:V200	4.47	No	No	0	5	5
152	R:R:F163	R:R:P164	4.33	No	No	0	4	8
153	R:R:F163	R:R:Y167	7.22	No	No	0	4	4
154	R:R:P164	R:R:Y196	8.34	No	Yes	0	8	6
155	R:R:I182	R:R:Q165	6.86	No	Yes	1	4	6
156	R:R:Q165	R:R:W184	6.57	Yes	Yes	1	6	5
157	R:R:Q165	R:R:Y196	15.78	Yes	Yes	1	6	6
158	L:L:M11	R:R:Q165	9.52	Yes	Yes	1	0	6
159	R:R:Y167	R:R:Y168	10.92	No	No	0	4	5
160	R:R:P185	R:R:Y168	15.3	No	No	0	4	5
161	R:R:E183	R:R:T170	16.93	No	No	0	3	4
162	R:R:E172	R:R:M174	6.77	No	No	0	3	1
163	L:L:P2	R:R:E172	6.29	No	No	0	0	3
164	R:R:T173	R:R:V178	6.35	No	No	0	2	4
165	R:R:M174	R:R:P175	6.71	No	No	0	1	2
166	R:R:R177	R:R:S176	11.86	No	No	0	2	5
167	L:L:F8	R:R:V179	10.49	Yes	No	1	0	3
168	L:L:F8	R:R:M181	8.71	Yes	No	0	0	4
169	R:R:I182	R:R:W184	17.62	No	Yes	1	4	5
170	R:R:E193	R:R:W184	18.54	No	Yes	0	4	5
171	R:R:W184	R:R:Y196	13.5	Yes	Yes	1	5	6
172	R:R:H197	R:R:W184	4.23	No	Yes	1	5	5
173	R:R:H187	R:R:P185	4.58	No	No	0	2	4
174	R:R:P185	R:R:Y192	5.56	No	No	0	4	4
175	R:R:H187	R:R:I191	6.63	No	No	0	2	1
176	R:R:I191	R:R:N189	11.33	No	No	0	1	3
177	R:R:E193	R:R:K190	12.15	No	No	0	4	2
178	R:R:E193	R:R:Y272	6.73	No	No	0	4	5
179	R:R:H197	R:R:Y196	7.62	No	Yes	1	5	6
180	R:R:V200	R:R:Y196	6.31	No	Yes	0	5	6
181	R:R:H197	R:R:Y272	15.24	No	No	0	5	5
182	R:R:H265	R:R:T201	12.32	Yes	No	0	7	6
183	R:R:L269	R:R:T201	5.9	No	No	0	5	6
184	R:R:H265	R:R:I204	5.3	Yes	No	0	7	6
185	R:R:F206	R:R:Y205	7.22	No	Yes	0	4	8
186	R:R:L209	R:R:Y205	4.69	No	Yes	0	6	8
187	R:R:L262	R:R:Y205	9.38	No	Yes	0	5	8
188	R:R:H265	R:R:Y205	9.8	Yes	Yes	0	7	8
189	R:R:F257	R:R:P208	4.33	No	No	0	9	9
190	R:R:V218	R:R:Y214	8.83	No	No	4	4	4
191	R:R:M250	R:R:Y216	21.55	Yes	Yes	0	8	9
192	R:R:M250	R:R:V219	6.09	Yes	No	0	8	8
193	R:R:G220	R:R:V247	5.52	No	No	0	5	6
194	R:R:K243	R:R:L223	5.64	No	No	0	7	8
195	R:R:R244	R:R:W224	33.99	No	No	0	5	4
196	R:R:V247	R:R:W224	7.36	No	No	0	6	4
197	R:R:Q239	R:R:Y236	4.51	No	No	0	4	5
198	R:R:K245	R:R:L308	4.23	No	No	0	8	7
199	R:R:M249	R:R:M250	4.33	Yes	Yes	0	8	8
200	R:R:I304	R:R:M249	7.29	No	Yes	0	8	8
201	R:R:L308	R:R:M249	5.65	No	Yes	0	7	8
202	R:R:T256	R:R:Y300	4.99	No	No	0	6	5
203	R:R:F257	R:R:W261	8.02	No	Yes	1	9	8
204	R:R:C260	R:R:L293	4.76	No	No	0	8	7
205	R:R:F264	R:R:W261	11.02	Yes	Yes	1	7	8
206	R:R:A294	R:R:W261	7.78	No	Yes	1	7	8
207	R:R:S297	R:R:W261	4.94	No	Yes	0	9	8
208	R:R:I266	R:R:L262	7.14	No	No	0	6	5
209	R:R:F264	R:R:H265	5.66	Yes	Yes	0	7	7
210	R:R:F264	R:R:F268	11.79	Yes	No	1	7	6
211	R:R:A294	R:R:F264	4.16	No	Yes	1	7	7
212	L:L:M11	R:R:F264	7.46	Yes	Yes	1	0	7
213	R:R:F267	R:R:F268	10.72	Yes	No	0	4	6
214	R:R:F267	R:R:Y278	14.44	Yes	No	0	4	2
215	R:R:F267	R:R:I283	5.02	Yes	No	0	4	4
216	R:R:F267	R:R:Y287	9.28	Yes	Yes	0	4	5
217	R:R:F267	R:R:I290	7.54	Yes	No	0	4	6
218	L:L:M11	R:R:F268	12.44	Yes	No	1	0	6
219	R:R:P271	R:R:Y278	16.69	No	No	0	4	2
220	R:R:I273	R:R:N274	4.25	No	No	0	5	4
221	R:R:L277	R:R:N274	4.12	Yes	No	0	5	4
222	R:R:D276	R:R:L277	4.07	No	Yes	0	1	5
223	R:R:F282	R:R:K280	8.69	No	No	0	3	4
224	R:R:Q284	R:R:Q285	8.96	No	No	0	4	1
225	R:R:M291	R:R:Y287	11.97	Yes	Yes	1	5	5
226	L:L:F7	R:R:Y287	8.25	No	Yes	1	0	5
227	L:L:G9	R:R:Y287	5.79	No	Yes	0	0	5
228	R:R:M291	R:R:M295	5.78	Yes	Yes	1	5	7
229	R:R:S296	R:R:Y300	7.63	No	No	0	5	5
230	R:R:N301	R:R:Y305	10.47	No	No	0	9	9
231	R:R:F312	R:R:Y305	6.19	Yes	No	0	9	9
232	R:R:C306	R:R:F316	8.38	No	No	0	7	6
233	R:R:F312	R:R:N309	7.25	Yes	No	0	9	8
234	R:R:D310	R:R:R313	9.53	No	No	0	4	8
235	R:R:K317	R:R:L314	4.23	No	No	0	5	4
236	L:L:K3	L:L:R1	11.14	No	No	0	0	0
237	L:L:K3	L:L:Q5	6.78	No	No	0	0	0
238	L:L:K3	L:L:Q6	4.07	No	No	0	0	0
239	L:L:P4	L:L:Q5	6.32	No	No	0	0	0
240	L:L:F8	L:L:Q6	14.05	Yes	No	0	0	0
241	R:R:F76	R:R:W155	4.01	No	Yes	0	6	9
242	R:R:A215	R:R:Y131	4	No	Yes	0	7	8
243	L:L:Q5	R:R:L279	3.99	No	No	0	0	2
244	R:R:R130	R:R:V126	3.92	No	No	0	9	9
245	R:R:A38	R:R:W292	3.89	No	Yes	0	4	5
246	R:R:A319	R:R:W55	3.89	No	Yes	0	4	4
247	R:R:R141	R:R:T67	3.88	Yes	No	0	5	8
248	R:R:V254	R:R:Y216	3.79	No	Yes	0	8	9
249	R:R:F312	R:R:I57	3.77	Yes	No	0	9	7
250	R:R:F70	R:R:I151	3.77	Yes	No	0	7	8
251	R:R:F76	R:R:M54	3.73	No	No	0	6	7
252	R:R:M63	R:R:R311	3.72	No	No	0	7	6
253	R:R:G166	R:R:S169	3.71	No	No	0	5	5
254	R:R:G49	R:R:V48	3.68	No	No	0	8	4
255	R:R:G213	R:R:V254	3.68	No	No	0	4	8
256	R:R:I154	R:R:Y121	3.63	No	No	0	7	5
257	R:R:I204	R:R:Y121	3.63	No	No	0	6	5
258	R:R:I212	R:R:Y216	3.63	No	Yes	0	8	9
259	R:R:G315	R:R:I56	3.53	No	Yes	0	6	8
260	R:R:P208	R:R:T124	3.5	No	No	0	9	7
261	R:R:A82	R:R:S46	3.42	No	No	0	6	8
262	R:R:L293	R:R:W292	3.42	No	Yes	0	7	5
263	R:R:A75	R:R:V53	3.39	No	No	0	9	8
264	R:R:A144	R:R:V66	3.39	No	Yes	0	2	6
265	R:R:I290	R:R:P263	3.39	No	No	0	6	9
266	R:R:C260	R:R:T256	3.38	No	No	0	8	6
267	R:R:E238	R:R:Y236	3.37	No	No	0	3	5
268	L:L:P4	R:R:M174	3.35	No	No	0	0	1
269	R:R:L207	R:R:P208	3.28	No	No	0	5	9
270	R:R:N189	R:R:P188	3.26	No	No	0	3	1
271	R:R:A162	R:R:I113	3.25	No	Yes	0	7	5
272	R:R:C307	R:R:K245	3.23	No	No	0	6	8
273	R:R:T86	R:R:V43	3.17	No	No	0	7	6
274	R:R:P140	R:R:Q139	3.16	No	No	0	6	4
275	R:R:A93	R:R:L288	3.15	No	No	0	5	3
276	R:R:A114	R:R:L159	3.15	No	No	0	5	4
277	R:R:A258	R:R:L209	3.15	No	No	0	5	6
278	R:R:I56	R:R:V52	3.07	Yes	No	0	8	6
279	R:R:I57	R:R:V72	3.07	No	No	0	7	6
280	R:R:I135	R:R:V219	3.07	Yes	No	0	7	8
281	R:R:I191	R:R:V195	3.07	No	No	0	1	4
282	R:R:I283	R:R:V286	3.07	No	No	0	4	5
283	R:R:I221	R:R:T217	3.04	No	No	0	3	3
284	R:R:M250	R:R:V246	3.04	Yes	No	0	8	7
285	R:R:M249	R:R:V253	3.04	Yes	No	0	8	7
286	R:R:L58	R:R:V72	2.98	No	No	0	2	6
287	R:R:L157	R:R:V153	2.98	No	No	0	4	3
288	R:R:L160	R:R:V156	2.98	No	No	0	4	3
289	R:R:L223	R:R:V247	2.98	No	No	0	8	6
290	R:R:I42	R:R:M299	2.92	No	No	0	7	7
291	R:R:I212	R:R:M123	2.92	No	No	0	8	8
292	R:R:G101	R:R:W98	2.81	No	Yes	0	8	8
293	R:R:A36	R:R:F90	2.77	No	No	0	6	6
294	R:R:L270	R:R:L277	2.77	No	Yes	0	4	5
295	R:R:F282	R:R:V286	2.62	No	No	0	3	5
296	R:R:A289	R:R:W35	2.59	No	No	0	5	4
297	R:R:A77	R:R:W155	2.59	No	Yes	0	8	9
298	R:R:H136	R:R:Q139	2.47	Yes	No	0	6	4
299	R:R:F282	R:R:L277	2.44	No	Yes	0	3	5
300	R:R:K194	R:R:Y272	2.39	No	No	0	3	5
301	R:R:L203	R:R:Y121	2.34	No	No	0	4	5
302	R:R:K248	R:R:W224	2.32	No	No	0	6	4
303	R:R:L34	R:R:W30	2.28	No	No	0	4	1
304	R:R:L159	R:R:W155	2.28	No	Yes	0	4	9
305	R:R:A114	R:R:A158	1.79	No	No	0	5	8
306	R:R:A118	R:R:A158	1.79	No	No	0	7	8
307	R:R:A115	R:R:S80	1.71	No	No	0	8	6
308	R:R:A146	R:R:S143	1.71	No	No	0	4	7
309	R:R:C199	R:R:V195	1.71	No	No	0	4	4
310	R:R:A79	R:R:V47	1.7	No	No	0	7	6
311	R:R:N274	R:R:P275	1.63	No	No	0	4	3
312	R:R:V47	R:R:V51	1.6	No	No	0	6	4
313	R:R:S143	R:R:T145	1.6	No	No	0	7	4
314	R:R:V149	R:R:V153	1.6	No	No	0	3	3
315	R:R:T40	R:R:V44	1.59	No	No	0	4	4
316	R:R:T45	R:R:V41	1.59	No	No	0	4	5
317	R:R:T45	R:R:V44	1.59	No	No	0	4	4
318	R:R:T171	R:R:V178	1.59	No	No	0	5	4
319	R:R:T256	R:R:V252	1.59	No	No	0	6	5
320	R:R:I198	R:R:V202	1.54	No	No	0	5	4
321	R:R:I198	R:R:K194	1.45	No	No	0	5	3
322	R:R:C306	R:R:R313	1.39	No	No	0	7	8
323	R:R:L157	R:R:L160	1.38	No	No	0	4	4
324	R:R:L314	R:R:R311	1.21	No	No	0	4	6
325	R:R:L314	R:R:R313	1.21	No	No	0	4	8
326	R:R:E183	R:R:Y168	1.12	No	No	0	3	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:N23	8.23	4	1	8
2	R:R:F25	11.284	5	1	6
3	R:R:Q27	7.6125	4	2	4
4	R:R:N50	6.3	4	0	9
5	R:R:W55	6.475	4	3	4
6	R:R:I56	4.51	5	3	8
7	R:R:H60	6.038	5	3	5
8	R:R:V66	6.23	4	5	6
9	R:R:F70	6.438	5	0	7
10	R:R:E78	9.0575	4	6	9
11	R:R:M81	4.5025	4	0	7
12	R:R:N85	6.315	6	1	6
13	R:R:N89	7.764	5	1	6
14	R:R:Y92	6.972	5	1	4
15	R:R:V94	6.6525	4	2	5
16	R:R:N96	7.38857	7	1	4
17	R:R:W98	8.28667	6	1	8
18	R:R:Y100	12.18	4	1	7
19	R:R:F107	7.135	4	1	4
20	R:R:H108	8.64857	7	1	5
21	R:R:F111	5.9125	4	1	4
22	R:R:P112	6.42	4	1	6
23	R:R:I113	5.49667	6	1	5
24	R:R:Y131	7.09	5	4	8
25	R:R:I135	7.23	5	4	7
26	R:R:H136	5.6725	4	4	6
27	R:R:R141	8.53	4	5	5
28	R:R:T147	6	4	5	7
29	R:R:W155	5.14667	6	0	9
30	R:R:Q165	8.844	5	1	6
31	R:R:W184	12.092	5	1	5
32	R:R:Y196	10.31	5	1	6
33	R:R:Y205	7.7725	4	0	8
34	R:R:Y216	8.302	5	0	9
35	R:R:M249	5.0775	4	0	8
36	R:R:M250	8.7525	4	0	8
37	R:R:W261	7.67667	6	1	8
38	R:R:F264	8.018	5	1	7
39	R:R:H265	8.27	4	0	7
40	R:R:F267	9.4	5	0	4
41	R:R:L277	3.35	4	0	5
42	R:R:Y287	8.686	5	1	5
43	R:R:M291	6.8925	4	1	5
44	R:R:W292	7.92	4	0	5
45	R:R:M295	5.8375	4	1	7
46	R:R:F312	6.008	5	0	9
47	L:L:F8	8.684	5	1	0
48	L:L:L10	6.5275	4	1	0
49	L:L:M11	8.4475	4	1	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:N23	R:R:V26	23.1269	5.91	Yes	No	0	8	1
2	R:R:F25	R:R:N96	36.6536	8.46	Yes	Yes	1	6	4
3	R:R:H95	R:R:V26	20.9832	6.92	No	No	0	5	1
4	R:R:F25	R:R:Q284	100	9.37	Yes	No	0	6	4
5	R:R:Q27	R:R:Q284	53.8081	10.24	Yes	No	0	4	4
6	R:R:Q27	R:R:V94	40.7709	4.3	Yes	Yes	2	4	5
7	R:R:Q284	R:R:Q285	44.6099	8.96	No	No	0	4	1
8	R:R:Q285	R:R:W35	42.3941	6.57	No	No	0	1	4
9	R:R:L288	R:R:W35	38.2768	18.22	No	No	0	3	4
10	R:R:F90	R:R:V94	52.1952	7.87	No	Yes	0	6	5
11	R:R:F90	R:R:Y39	46.2692	16.5	No	No	0	6	7
12	R:R:L288	R:R:Y39	33.9792	4.69	No	No	0	3	7
13	R:R:W292	R:R:Y39	74.5903	6.75	Yes	No	0	5	7
14	R:R:I42	R:R:W292	32.2117	17.62	No	Yes	0	7	5
15	L:L:F7	R:R:F25	72.6683	16.08	No	Yes	1	0	6
16	L:L:F7	R:R:Y287	88.4211	8.25	No	Yes	1	0	5
17	R:R:M291	R:R:Y287	39.6681	11.97	Yes	Yes	1	5	5
18	R:R:M291	R:R:M295	34.9428	5.78	Yes	Yes	1	5	7
19	R:R:I42	R:R:M299	26.868	2.92	No	No	0	7	7
20	R:R:M299	R:R:T45	21.514	7.53	No	No	0	7	4
21	R:R:M295	R:R:M81	74.8068	4.33	Yes	Yes	0	7	7
22	R:R:M81	R:R:T298	93.3268	4.52	Yes	No	0	7	9
23	R:R:S46	R:R:T298	16.7835	7.99	No	No	0	8	9
24	R:R:N50	R:R:S46	13.2382	4.47	Yes	No	0	9	8
25	R:R:E78	R:R:T298	76.363	9.88	Yes	No	0	9	9
26	R:R:E78	R:R:N50	15.4746	7.89	Yes	Yes	0	9	9
27	R:R:N50	R:R:P302	11.8365	8.15	Yes	No	0	9	9
28	R:R:A79	R:R:N50	11.8365	4.69	No	Yes	0	7	9
29	R:R:E78	R:R:N301	56.8639	11.83	Yes	No	6	9	9
30	R:R:N301	R:R:Y305	58.9354	10.47	No	No	0	9	9
31	R:R:F312	R:R:Y305	55.859	6.19	Yes	No	0	9	9
32	R:R:F312	R:R:I56	39.6321	6.28	Yes	Yes	0	9	8
33	R:R:I56	R:R:V52	10.7441	3.07	Yes	No	0	8	6
34	R:R:H60	R:R:I56	10.404	5.3	Yes	Yes	3	5	8
35	R:R:I56	R:R:M63	14.9284	4.37	Yes	No	3	8	7
36	R:R:F312	R:R:I57	13.6298	3.77	Yes	No	0	9	7
37	R:R:M63	R:R:R311	12.9599	3.72	No	No	0	7	6
38	R:R:N96	R:R:Y92	51.5665	6.98	Yes	Yes	1	4	4
39	R:R:W98	R:R:Y92	25.049	11.58	Yes	Yes	1	8	4
40	R:R:H108	R:R:W98	28.3108	4.23	Yes	Yes	1	5	8
41	R:R:H108	R:R:P112	54.3543	10.68	Yes	Yes	1	5	6
42	R:R:F111	R:R:P112	83.8967	5.78	Yes	Yes	1	4	6
43	R:R:F111	R:R:W155	80.0165	5.01	Yes	Yes	0	4	9
44	R:R:N73	R:R:W155	50.1546	7.91	No	Yes	0	9	9
45	R:R:I151	R:R:N73	46.0373	14.16	No	No	0	8	9
46	R:R:F70	R:R:I151	42.7806	3.77	Yes	No	0	7	8
47	R:R:D129	R:R:F70	10.3422	8.36	No	Yes	0	9	7
48	L:L:L10	R:R:Y92	57.3586	5.86	Yes	Yes	1	0	4
49	L:L:L10	R:R:H108	24.8274	5.14	Yes	Yes	1	0	5
50	R:R:N89	R:R:Y287	26.095	8.14	Yes	Yes	1	6	5
51	R:R:H108	R:R:N89	13.2227	12.75	Yes	Yes	1	5	6
52	R:R:N85	R:R:N89	19.3548	5.45	Yes	Yes	1	6	6
53	R:R:N85	R:R:P112	38.8437	4.89	Yes	Yes	1	6	6
54	R:R:M291	R:R:N85	12.2127	4.21	Yes	Yes	1	5	6
55	R:R:F70	R:R:T147	23.4	5.19	Yes	Yes	0	7	7
56	R:R:N73	R:R:S122	12.4549	5.96	No	No	0	9	8
57	R:R:L74	R:R:S122	10.7132	4.5	No	No	0	9	8
58	R:R:F76	R:R:W155	13.6813	4.01	No	Yes	0	6	9
59	R:R:M81	R:R:V116	40.7761	4.56	Yes	No	0	7	7
60	L:L:?12	R:R:N85	26.7855	10.2	No	Yes	1	0	6
61	L:L:?12	R:R:H108	18.4891	6.36	No	Yes	1	0	5
62	L:L:F8	R:R:N96	12.7744	6.04	Yes	Yes	1	0	4
63	L:L:L10	R:R:N109	38.9879	8.24	Yes	No	0	0	5
64	R:R:N109	R:R:S169	18.7159	5.96	No	No	0	5	5
65	R:R:K106	R:R:S169	13.4185	9.18	No	No	0	6	5
66	R:R:K106	R:R:L102	10.7544	5.64	No	No	0	6	3
67	R:R:I113	R:R:N109	33.1135	4.25	Yes	No	0	5	5
68	R:R:L159	R:R:W155	10.2546	2.28	No	Yes	0	4	9
69	R:R:F117	R:R:I113	13.7174	5.02	No	Yes	0	7	5
70	R:R:I113	R:R:Q165	43.368	5.49	Yes	Yes	1	5	6
71	R:R:F267	R:R:Y287	53.9988	9.28	Yes	Yes	0	4	5
72	R:R:F267	R:R:F268	42.8115	10.72	Yes	No	0	4	6
73	L:L:M11	R:R:F268	13.6813	12.44	Yes	No	1	0	6
74	L:L:M11	R:R:Q165	31.5006	9.52	Yes	Yes	1	0	6
75	R:R:F264	R:R:F268	29.2229	11.79	Yes	No	1	7	6
76	R:R:F264	R:R:W261	58.3995	11.02	Yes	Yes	1	7	8
77	R:R:F117	R:R:I204	10.0794	11.3	No	No	0	7	6
78	R:R:F264	R:R:H265	20.1175	5.66	Yes	Yes	0	7	7
79	R:R:F257	R:R:W261	64.1709	8.02	No	Yes	1	9	8
80	R:R:F257	R:R:P208	63.0939	4.33	No	No	0	9	9
81	R:R:P208	R:R:T124	60.4658	3.5	No	No	0	9	7
82	R:R:I212	R:R:T124	57.7966	6.08	No	No	0	8	7
83	R:R:I212	R:R:Y216	55.0861	3.63	No	Yes	0	8	9
84	R:R:I135	R:R:V219	21.4624	3.07	Yes	No	0	7	8
85	R:R:M250	R:R:V219	35.4633	6.09	Yes	No	0	8	8
86	R:R:M250	R:R:Y216	46.8927	21.55	Yes	Yes	0	8	9
87	R:R:I134	R:R:V219	13.5422	12.29	No	No	0	8	8
88	R:R:I134	R:R:L223	11.8778	4.28	No	No	0	8	8
89	R:R:Q165	R:R:Y196	45.4602	15.78	Yes	Yes	1	6	6
90	R:R:F163	R:R:P164	29.5733	4.33	No	No	0	4	8
91	R:R:P164	R:R:Y196	31.7737	8.34	No	Yes	0	8	6
92	R:R:F163	R:R:Y167	27.3421	7.22	No	No	0	4	4
93	R:R:Q165	R:R:W184	25.456	6.57	Yes	Yes	1	6	5
94	R:R:Y167	R:R:Y168	25.1005	10.92	No	No	0	4	5
95	R:R:P185	R:R:Y168	18.3088	15.3	No	No	0	4	5
96	L:L:P4	R:R:M174	13.5371	3.35	No	No	0	0	1
97	L:L:P4	L:L:Q5	16.8968	6.32	No	No	0	0	0
98	L:L:K3	L:L:Q5	23.5855	6.78	No	No	0	0	0
99	L:L:K3	L:L:Q6	30.2329	4.07	No	No	0	0	0
100	L:L:F8	L:L:Q6	33.5412	14.05	Yes	No	0	0	0
101	R:R:E193	R:R:W184	12.9341	18.54	No	Yes	0	4	5
102	R:R:H197	R:R:W184	10.605	4.23	No	Yes	1	5	5
103	R:R:H197	R:R:Y196	11.2903	7.62	No	Yes	1	5	6
104	R:R:H187	R:R:P185	13.9699	4.58	No	No	0	2	4
105	R:R:H187	R:R:I191	11.6665	6.63	No	No	0	2	1
106	R:R:H197	R:R:Y272	17.5925	15.24	No	No	0	5	5
107	R:R:H265	R:R:Y205	14.0008	9.8	Yes	Yes	0	7	8
108	R:R:L293	R:R:W292	32.2117	3.42	No	Yes	0	7	5
109	R:R:C260	R:R:L293	26.868	4.76	No	No	0	8	7
110	R:R:C260	R:R:T256	21.514	3.38	No	No	0	8	6
111	R:R:T256	R:R:Y300	10.775	4.99	No	No	0	6	5
112	R:R:F267	R:R:I283	19.3548	5.02	Yes	No	0	4	4
113	R:R:I283	R:R:V286	17.5255	3.07	No	No	0	4	5
114	R:R:F282	R:R:V286	15.6189	2.62	No	No	0	3	5
115	R:R:F282	R:R:L277	11.7747	2.44	No	Yes	0	3	5
116	R:R:K194	R:R:Y272	20.2051	2.39	No	No	0	3	5
117	R:R:T45	R:R:V44	10.775	1.59	No	No	0	4	4
118	R:R:I198	R:R:K194	13.4855	1.45	No	No	0	5	3
119	L:L:F7	R:R:N96	14.8253	8.46	No	Yes	1	0	4
120	R:R:N23	R:R:N96	21.3491	4.09	Yes	Yes	1	8	4
121	R:R:H95	R:R:V94	14.645	8.3	No	Yes	0	5	5
122	L:L:L10	R:R:N89	14.4749	6.87	Yes	Yes	1	0	6
123	R:R:H108	R:R:N85	16.33	8.93	Yes	Yes	1	5	6
124	L:L:M11	R:R:I113	16.5722	4.37	Yes	Yes	1	0	5
125	L:L:?12	R:R:I113	43.3989	10.6	No	Yes	1	0	5
126	R:R:M295	R:R:N85	43.2392	4.21	Yes	Yes	1	7	6
127	L:L:F8	R:R:Y92	26.6258	4.13	Yes	Yes	1	0	4
128	R:R:V116	R:R:W261	40.1886	4.9	No	Yes	0	7	8
129	L:L:M11	R:R:F264	34.5821	7.46	Yes	Yes	1	0	7

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:F25	R:R:N23	8.46	1	Yes	Yes	6	8	1	2
R:R:N23	R:R:N96	4.09	1	Yes	Yes	8	4	2	1
R:R:N23	R:R:R177	14.46	1	Yes	No	8	2	2	2
R:R:F25	R:R:Q24	14.05	1	Yes	No	6	3	1	2
R:R:F25	R:R:N96	8.46	1	Yes	Yes	6	4	1	1
R:R:F25	R:R:Q284	9.37	1	Yes	No	6	4	1	2
L:L:F7	R:R:F25	16.08	1	No	Yes	0	6	0	1
R:R:N85	R:R:N89	5.45	1	Yes	Yes	6	6	1	1
R:R:H108	R:R:N85	8.93	1	Yes	Yes	5	6	1	1
R:R:N85	R:R:P112	4.89	1	Yes	Yes	6	6	1	2
R:R:M291	R:R:N85	4.21	1	Yes	Yes	5	6	2	1
R:R:M295	R:R:N85	4.21	1	Yes	Yes	7	6	2	1
L:L:?12	R:R:N85	10.2	1	No	Yes	0	6	0	1
R:R:H108	R:R:V88	12.45	1	Yes	No	5	5	1	2
R:R:H108	R:R:N89	12.75	1	Yes	Yes	5	6	1	1
R:R:N89	R:R:Y287	8.14	1	Yes	Yes	6	5	1	1
R:R:M291	R:R:N89	5.61	1	Yes	Yes	5	6	2	1
L:L:L10	R:R:N89	6.87	1	Yes	Yes	0	6	0	1
R:R:N96	R:R:Y92	6.98	1	Yes	Yes	4	4	1	1
R:R:W98	R:R:Y92	11.58	1	Yes	Yes	8	4	2	1
R:R:V179	R:R:Y92	6.31	1	No	Yes	3	4	1	1
L:L:F8	R:R:Y92	4.13	1	Yes	Yes	0	4	0	1
L:L:L10	R:R:Y92	5.86	1	Yes	Yes	0	4	0	1
R:R:N96	R:R:R177	13.26	1	Yes	No	4	2	1	2
R:R:N96	R:R:V179	4.43	1	Yes	No	4	3	1	1
L:L:F7	R:R:N96	8.46	1	No	Yes	0	4	0	1
L:L:F8	R:R:N96	6.04	1	Yes	Yes	0	4	0	1
R:R:H108	R:R:W98	4.23	1	Yes	Yes	5	8	1	2
R:R:H108	R:R:P112	10.68	1	Yes	Yes	5	6	1	2
L:L:L10	R:R:H108	5.14	1	Yes	Yes	0	5	0	1
L:L:?12	R:R:H108	6.36	1	No	Yes	0	5	0	1
R:R:I113	R:R:N109	4.25	1	Yes	No	5	5	1	1
R:R:N109	R:R:S169	5.96	0	No	No	5	5	1	2
L:L:L10	R:R:N109	8.24	1	Yes	No	0	5	0	1
R:R:F117	R:R:I113	5.02	0	No	Yes	7	5	2	1
R:R:I113	R:R:Q165	5.49	1	Yes	Yes	5	6	1	1
L:L:M11	R:R:I113	4.37	1	Yes	Yes	0	5	0	1
L:L:?12	R:R:I113	10.6	1	No	Yes	0	5	0	1
R:R:I182	R:R:Q165	6.86	1	No	Yes	4	6	2	1
R:R:Q165	R:R:W184	6.57	1	Yes	Yes	6	5	1	2
R:R:Q165	R:R:Y196	15.78	1	Yes	Yes	6	6	1	2
L:L:M11	R:R:Q165	9.52	1	Yes	Yes	0	6	0	1
R:R:E172	R:R:M174	6.77	0	No	No	3	1	1	1
L:L:P2	R:R:E172	6.29	0	No	No	0	3	0	1
R:R:M174	R:R:P175	6.71	0	No	No	1	2	1	2
L:L:F8	R:R:V179	10.49	1	Yes	No	0	3	0	1
L:L:F8	R:R:M181	8.71	1	Yes	No	0	4	0	1
R:R:I182	R:R:W184	17.62	1	No	Yes	4	5	2	2
R:R:W184	R:R:Y196	13.5	1	Yes	Yes	5	6	2	2
R:R:F264	R:R:W261	11.02	1	Yes	Yes	7	8	1	2
R:R:A294	R:R:W261	7.78	1	No	Yes	7	8	2	2
R:R:F264	R:R:H265	5.66	1	Yes	Yes	7	7	1	2
R:R:F264	R:R:F268	11.79	1	Yes	No	7	6	1	1
R:R:A294	R:R:F264	4.16	1	No	Yes	7	7	2	1
L:L:M11	R:R:F264	7.46	1	Yes	Yes	0	7	0	1
R:R:F267	R:R:F268	10.72	0	Yes	No	4	6	2	1
R:R:F267	R:R:Y287	9.28	0	Yes	Yes	4	5	2	1
L:L:M11	R:R:F268	12.44	1	Yes	No	0	6	0	1
R:R:M291	R:R:Y287	11.97	1	Yes	Yes	5	5	2	1
L:L:F7	R:R:Y287	8.25	1	No	Yes	0	5	0	1
L:L:G9	R:R:Y287	5.79	0	No	Yes	0	5	0	1
R:R:M291	R:R:M295	5.78	1	Yes	Yes	5	7	2	2
L:L:Q5	R:R:L279	3.99	0	No	No	0	2	0	1
L:L:P4	R:R:M174	3.35	0	No	No	0	1	0	1
R:R:A162	R:R:I113	3.25	0	No	Yes	7	5	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	7P00_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	4.05
Number of Linked Nodes	278
Number of Links	326
Number of Hubs	49
Number of Links mediated by Hubs	176
Number of Communities	6
Number of Nodes involved in Communities	63
Number of Links involved in Communities	96

Path Summary
Number Of Nodes in MetaPath	130
Number Of Links MetaPath	129
Number of Shortest Paths	69573
Length Of Smallest Path	3
Average Path Length	14.254
Length of Longest Path	30
Minimum Path Strength	1.21
Average Path Strength	7.51551
Maximum Path Strength	20.675
Minimum Path Correlation	0.7
Average Path Correlation	0.924212
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	4.34783
Average % Of Corr. Nodes	47.3045
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	48.9407
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	NH2
PDB Residues	L:L:?12
Environment Details	Open EMBL-EBI Page
Code	NH2
Name	AMINO GROUP
Synonyms
Identifier
Formula	H2 N
Molecular Weight	16.023
SMILES
PubChem	123329
Formal Charge	0
Total Atoms	3
Total Chiral Atoms	0
Total Bonds	2
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P25103
Sequence	>7P00_nogp_Chain_R P N Q F V Q P A W Q I V L W A A A Y T V I V V T S V V G N V V V M W I I L A H K R M R T V T N Y F L V N L A F A E A S M A A F N T V V N F T Y A V H N E W Y Y G L F Y C K F H N F F P I A A V F A S I Y S M T A V A F D R Y M A I I H P L Q P R L S A T A T K V V I C V I W V L A L L L A F P Q G Y Y S T T E T M P S R V V C M I E W P E H P N K I Y E K V Y H I C V T V L I Y F L P L L V I G Y A Y T V V G I T L W A Y H E Q V S A K R K V V K M M I V V V C T F A I C W L P F H I F F L L P Y I N P D L Y L K K F I Q Q V Y L A I M W L A M S S T M Y N P I I Y C C L N D R F R L G F K H A Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	6HLL	A	Peptide	Tachykinin	NK₁	Homo sapiens	CP99994	-	-	3.27	2019-01-16	doi.org/10.1038/s41467-018-07939-8
	6HLO	A	Peptide	Tachykinin	NK₁	Homo sapiens	Aprepitant	-	-	2.4	2019-01-16	doi.org/10.1038/s41467-018-07939-8
	6HLP	A	Peptide	Tachykinin	NK₁	Homo sapiens	Netupitant	-	-	2.2	2019-01-16	doi.org/10.1038/s41467-018-07939-8
	6J20	A	Peptide	Tachykinin	NK₁	Homo sapiens	Aprepitant	-	-	2.7	2019-03-06	doi.org/10.1038/s41467-019-08568-5
	6J21	A	Peptide	Tachykinin	NK₁	Homo sapiens	Aprepitant	-	-	3.2	2019-03-06	doi.org/10.1038/s41467-019-08568-5
	7RMG	A	Peptide	Tachykinin	NK₁	Homo sapiens	Substance-P	-	chim(Gs-CtGq)/β1/γ2	3	2021-11-03	doi.org/10.1038/s41589-021-00890-8
	7RMG (No Gprot)	A	Peptide	Tachykinin	NK₁	Homo sapiens	Substance-P	-		3	2021-11-03	doi.org/10.1038/s41589-021-00890-8
	7RMH	A	Peptide	Tachykinin	NK₁	Homo sapiens	Substance-P	-	Gs/β1/γ2	3.1	2021-11-03	doi.org/10.1038/s41589-021-00890-8
	7RMH (No Gprot)	A	Peptide	Tachykinin	NK₁	Homo sapiens	Substance-P	-		3.1	2021-11-03	doi.org/10.1038/s41589-021-00890-8
	7RMI	A	Peptide	Tachykinin	NK₁	Homo sapiens	Substance-P	-	chim(Gs-CtGq)/β1/γ2	3.2	2021-11-03	doi.org/10.1038/s41589-021-00890-8
	7RMI (No Gprot)	A	Peptide	Tachykinin	NK₁	Homo sapiens	Substance-P	-		3.2	2021-11-03	doi.org/10.1038/s41589-021-00890-8
	8U26	A	Peptide	Tachykinin	NK₁	Homo sapiens	Protachykinin-1	-	Gs/β1/γ2	2.5	2023-11-15	doi.org/10.1038/s41592-023-02082-9
	8U26 (No Gprot)	A	Peptide	Tachykinin	NK₁	Homo sapiens	Protachykinin-1	-		2.5	2023-11-15	doi.org/10.1038/s41592-023-02082-9
	6E59	A	Peptide	Tachykinin	NK₁	Homo sapiens	L-760735	-	-	3.4	2018-12-12	doi.org/10.1073/pnas.1812717115
	7P00	A	Peptide	Tachykinin	NK₁	Homo sapiens	Substance-P	-	chim(NtGi1-Gs-CtGq)/β1/γ2	2.71	2021-12-15	doi.org/10.1126/sciadv.abk2872
	7P00 (No Gprot)	A	Peptide	Tachykinin	NK₁	Homo sapiens	Substance-P	-		2.71	2021-12-15	doi.org/10.1126/sciadv.abk2872
	7P02	A	Peptide	Tachykinin	NK₁	Homo sapiens	Protachykinin-1	-	chim(NtGi1-Gs)/β1/γ2	2.87	2021-12-15	doi.org/10.1126/sciadv.abk2872
	7P02 (No Gprot)	A	Peptide	Tachykinin	NK₁	Homo sapiens	Protachykinin-1	-		2.87	2021-12-15	doi.org/10.1126/sciadv.abk2872

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 7P00_nogp.zip

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