psnGPCR

Press and hold down the left mouse button and move the mouse to rotate.
Press and hold down the central mouse button and move the mouse to translate.
Use the mouse wheel to zoom in or out.
Click on any atom on your molecule and the corresponding residue label will be placed beneath the viewer.

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:F25	R:R:N23	8.46	Yes	No	0	6	8
2	R:R:N23	R:R:V26	5.91	No	No	0	8	1
3	R:R:N23	R:R:R177	14.46	No	Yes	0	8	2
4	R:R:F25	R:R:Q24	14.05	Yes	No	1	6	3
5	R:R:K281	R:R:Q24	5.42	No	No	1	2	3
6	R:R:F25	R:R:K281	4.96	Yes	No	1	6	2
7	R:R:F25	R:R:Q284	11.71	Yes	Yes	1	6	4
8	L:L:F7	R:R:F25	15	Yes	Yes	1	0	6
9	R:R:H95	R:R:V26	11.07	No	No	0	5	1
10	R:R:Q27	R:R:Q31	7.68	Yes	Yes	1	4	2
11	R:R:I32	R:R:Q27	6.86	No	Yes	0	3	4
12	R:R:Q27	R:R:Q284	14.08	Yes	Yes	1	4	4
13	R:R:Q27	R:R:Q285	7.68	Yes	Yes	1	4	1
14	R:R:P28	R:R:W30	8.11	No	No	1	2	1
15	R:R:P28	R:R:Q31	15.79	No	Yes	1	2	2
16	R:R:Q31	R:R:W30	9.86	Yes	No	1	2	1
17	R:R:Q285	R:R:Q31	6.4	Yes	Yes	1	1	2
18	R:R:I32	R:R:V94	4.61	No	No	0	3	5
19	R:R:Q285	R:R:W35	6.57	Yes	No	0	1	4
20	R:R:L288	R:R:W35	17.08	No	No	0	3	4
21	R:R:F90	R:R:Y39	18.57	No	No	0	6	7
22	R:R:L288	R:R:Y39	5.86	No	No	0	3	7
23	R:R:W292	R:R:Y39	4.82	No	No	0	5	7
24	R:R:I42	R:R:W292	9.4	No	No	0	7	5
25	R:R:T86	R:R:V43	4.76	No	No	0	7	6
26	R:R:M299	R:R:T45	6.02	No	No	0	7	4
27	R:R:S46	R:R:T298	6.4	No	No	0	8	9
28	R:R:E78	R:R:N50	9.2	Yes	No	0	9	9
29	R:R:A79	R:R:N50	4.69	No	No	0	7	9
30	R:R:N50	R:R:P302	8.15	No	No	0	9	9
31	R:R:F316	R:R:V52	6.55	Yes	No	0	6	6
32	R:R:F312	R:R:V53	5.24	Yes	No	0	9	8
33	R:R:A59	R:R:W55	7.78	No	Yes	0	4	4
34	R:R:H60	R:R:W55	6.35	No	Yes	0	5	4
35	R:R:H318	R:R:W55	5.29	No	Yes	0	3	4
36	R:R:G315	R:R:I56	5.29	No	No	0	6	8
37	R:R:F316	R:R:I56	6.28	Yes	No	0	6	8
38	R:R:I57	R:R:N68	9.91	No	No	0	7	8
39	R:R:I57	R:R:V72	4.61	No	No	0	7	6
40	R:R:F312	R:R:I57	5.02	Yes	No	0	9	7
41	R:R:L58	R:R:R64	6.07	No	No	0	2	6
42	R:R:R311	R:R:R62	14.93	No	No	0	6	5
43	R:R:F312	R:R:M63	7.46	Yes	No	0	9	7
44	R:R:T65	R:R:T67	4.71	No	No	0	7	8
45	R:R:N68	R:R:T65	5.85	No	No	0	8	7
46	R:R:V66	R:R:Y69	8.83	Yes	No	0	6	5
47	R:R:R141	R:R:V66	9.15	Yes	Yes	3	5	6
48	R:R:T147	R:R:V66	4.76	Yes	Yes	3	7	6
49	R:R:L71	R:R:N68	5.49	No	No	0	8	8
50	R:R:K148	R:R:Y69	5.97	No	No	0	2	5
51	R:R:D129	R:R:F70	14.33	No	Yes	0	9	7
52	R:R:F70	R:R:T147	9.08	Yes	Yes	0	7	7
53	R:R:F70	R:R:V150	6.55	Yes	No	0	7	5
54	R:R:L71	R:R:R130	4.86	No	No	0	8	9
55	R:R:L71	R:R:Y305	8.21	No	No	0	8	9
56	R:R:N73	R:R:S122	8.94	Yes	No	0	9	8
57	R:R:I151	R:R:N73	14.16	No	Yes	0	8	9
58	R:R:N73	R:R:W155	5.65	Yes	Yes	0	9	9
59	R:R:E78	R:R:L74	6.63	Yes	No	2	9	9
60	R:R:L74	R:R:N301	6.87	No	No	2	9	9
61	R:R:F76	R:R:S80	5.28	No	No	0	6	6
62	R:R:F76	R:R:W155	7.02	No	Yes	0	6	9
63	R:R:E78	R:R:T298	11.29	Yes	No	0	9	9
64	R:R:E78	R:R:N301	11.83	Yes	No	2	9	9
65	R:R:F111	R:R:S80	5.28	No	No	0	4	6
66	R:R:M81	R:R:V116	6.09	Yes	No	4	7	7
67	R:R:M81	R:R:W261	4.65	Yes	Yes	4	7	8
68	R:R:M81	R:R:T298	6.02	Yes	No	0	7	9
69	R:R:F111	R:R:F84	8.57	No	No	0	4	5
70	R:R:N85	R:R:N89	5.45	Yes	Yes	1	6	6
71	R:R:H108	R:R:N85	7.65	Yes	Yes	1	5	6
72	R:R:N85	R:R:P112	4.89	Yes	No	1	6	6
73	R:R:M295	R:R:N85	7.01	No	Yes	0	7	6
74	L:L:?12	R:R:N85	10.2	No	Yes	0	0	6
75	R:R:M295	R:R:T86	10.54	No	No	0	7	7
76	R:R:V88	R:R:Y100	11.36	No	Yes	1	5	7
77	R:R:V88	R:R:Y104	7.57	No	Yes	1	5	5
78	R:R:H108	R:R:V88	16.61	Yes	No	1	5	5
79	R:R:H108	R:R:N89	12.75	Yes	Yes	1	5	6
80	R:R:N89	R:R:Y287	8.14	Yes	Yes	1	6	5
81	R:R:M291	R:R:N89	8.41	No	Yes	1	5	6
82	L:L:L10	R:R:N89	6.87	Yes	Yes	1	0	6
83	R:R:T91	R:R:Y100	6.24	No	Yes	0	4	7
84	R:R:N96	R:R:Y92	11.63	Yes	No	0	4	4
85	R:R:W98	R:R:Y92	12.54	Yes	No	0	8	4
86	L:L:L10	R:R:Y92	4.69	Yes	No	0	0	4
87	R:R:H95	R:R:V94	6.92	No	No	0	5	5
88	R:R:E97	R:R:H95	6.15	No	No	0	4	5
89	R:R:N96	R:R:R177	9.64	Yes	Yes	0	4	2
90	L:L:F7	R:R:N96	10.87	Yes	Yes	0	0	4
91	L:L:F8	R:R:N96	9.67	Yes	Yes	0	0	4
92	R:R:E97	R:R:Y99	19.08	No	No	0	4	2
93	R:R:E97	R:R:R177	5.82	No	Yes	0	4	2
94	R:R:W98	R:R:Y100	18.33	Yes	Yes	1	8	7
95	R:R:W98	R:R:Y104	4.82	Yes	Yes	1	8	5
96	R:R:C105	R:R:W98	5.22	No	Yes	1	9	8
97	R:R:C180	R:R:W98	7.84	Yes	Yes	1	9	8
98	R:R:Y100	R:R:Y104	18.86	Yes	Yes	1	7	5
99	R:R:L102	R:R:T171	10.32	No	No	0	3	5
100	R:R:F107	R:R:Y104	13.41	No	Yes	0	4	5
101	R:R:C105	R:R:C180	7.28	No	Yes	1	9	9
102	R:R:K106	R:R:S169	4.59	No	No	0	6	5
103	R:R:F107	R:R:F111	6.43	No	No	0	4	4
104	R:R:H108	R:R:P112	10.68	Yes	No	1	5	6
105	R:R:N109	R:R:S169	5.96	No	No	0	5	5
106	R:R:C180	R:R:N109	4.72	Yes	No	1	9	5
107	L:L:L10	R:R:N109	9.61	Yes	No	1	0	5
108	R:R:F110	R:R:L159	4.87	No	No	0	6	4
109	R:R:I113	R:R:Q165	8.23	Yes	Yes	5	5	6
110	L:L:M11	R:R:I113	5.83	No	Yes	5	0	5
111	L:L:?12	R:R:I113	10.6	No	Yes	0	0	5
112	R:R:V116	R:R:W261	6.13	No	Yes	4	7	8
113	R:R:F117	R:R:L161	17.05	No	No	0	7	5
114	R:R:F117	R:R:I204	11.3	No	No	0	7	6
115	R:R:A118	R:R:W155	9.08	No	Yes	0	7	9
116	R:R:F257	R:R:I120	7.54	Yes	No	0	9	7
117	R:R:I204	R:R:Y121	6.04	No	No	0	6	5
118	R:R:I212	R:R:T124	6.08	No	No	0	8	7
119	R:R:R130	R:R:V126	7.85	No	No	0	9	9
120	R:R:A127	R:R:Y216	6.67	No	Yes	0	9	9
121	R:R:F128	R:R:M132	8.71	No	No	0	5	5
122	R:R:D129	R:R:R141	7.15	No	Yes	0	9	5
123	R:R:R130	R:R:Y216	11.32	No	Yes	0	9	9
124	R:R:I135	R:R:Y131	21.76	Yes	Yes	6	7	8
125	R:R:H136	R:R:Y131	5.44	Yes	Yes	6	6	8
126	R:R:I134	R:R:V219	6.14	No	Yes	0	8	8
127	R:R:H136	R:R:I135	9.28	Yes	Yes	6	6	7
128	R:R:I135	R:R:V218	4.61	Yes	No	0	7	4
129	R:R:R141	R:R:T147	10.35	Yes	Yes	3	5	7
130	R:R:F163	R:R:Y167	7.22	No	No	0	4	4
131	R:R:P164	R:R:Y196	8.34	No	Yes	0	8	6
132	R:R:I182	R:R:Q165	8.23	No	Yes	0	4	6
133	R:R:Q165	R:R:Y196	13.53	Yes	Yes	0	6	6
134	L:L:M11	R:R:Q165	8.16	No	Yes	5	0	6
135	R:R:Y167	R:R:Y168	11.91	No	No	0	4	5
136	R:R:W184	R:R:Y168	4.82	Yes	No	0	5	5
137	R:R:P185	R:R:Y168	15.3	No	No	0	4	5
138	R:R:E183	R:R:T170	15.52	No	No	0	3	4
139	R:R:E172	R:R:M174	5.41	No	No	0	3	1
140	R:R:M174	R:R:P175	5.03	No	No	0	1	2
141	R:R:R177	R:R:S176	11.86	Yes	No	0	2	5
142	R:R:R177	R:R:V179	6.54	Yes	No	0	2	3
143	L:L:F8	R:R:V179	11.8	Yes	No	0	0	3
144	L:L:L10	R:R:C180	4.76	Yes	Yes	1	0	9
145	L:L:F8	R:R:M181	8.71	Yes	No	0	0	4
146	R:R:I182	R:R:W184	12.92	No	Yes	0	4	5
147	R:R:E193	R:R:W184	14.17	No	Yes	0	4	5
148	R:R:W184	R:R:Y196	13.5	Yes	Yes	0	5	6
149	R:R:P185	R:R:Y192	6.95	No	No	0	4	4
150	R:R:H187	R:R:I191	7.95	No	No	0	2	1
151	R:R:I191	R:R:N189	11.33	No	No	0	1	3
152	R:R:E193	R:R:K190	8.1	No	No	0	4	2
153	R:R:E193	R:R:Y272	12.35	No	No	0	4	5
154	R:R:K194	R:R:Y272	13.14	No	No	0	3	5
155	R:R:H197	R:R:Y196	7.62	No	Yes	0	5	6
156	R:R:V200	R:R:Y196	7.57	No	Yes	0	5	6
157	R:R:H197	R:R:Y272	15.24	No	No	0	5	5
158	R:R:H265	R:R:T201	12.32	Yes	No	0	7	6
159	R:R:L269	R:R:T201	7.37	No	No	0	5	6
160	R:R:H265	R:R:I204	5.3	Yes	No	0	7	6
161	R:R:F206	R:R:Y205	8.25	No	Yes	0	4	8
162	R:R:L209	R:R:Y205	4.69	No	Yes	0	6	8
163	R:R:L262	R:R:Y205	10.55	No	Yes	0	5	8
164	R:R:H265	R:R:Y205	7.62	Yes	Yes	0	7	8
165	R:R:F257	R:R:L209	4.87	Yes	No	0	9	6
166	R:R:A258	R:R:L209	4.73	No	No	0	5	6
167	R:R:V218	R:R:Y214	6.31	No	No	0	4	4
168	R:R:M250	R:R:Y216	19.16	Yes	Yes	0	8	9
169	R:R:M250	R:R:V219	6.09	Yes	Yes	0	8	8
170	R:R:R244	R:R:W224	36.99	No	No	0	5	4
171	R:R:V247	R:R:W224	7.36	No	No	0	6	4
172	R:R:K243	R:R:Q239	8.14	No	No	0	7	4
173	R:R:I304	R:R:M249	7.29	No	No	0	8	8
174	R:R:L308	R:R:M249	8.48	No	No	0	7	8
175	R:R:T256	R:R:Y300	18.73	No	No	0	6	5
176	R:R:F257	R:R:W261	7.02	Yes	Yes	0	9	8
177	R:R:F264	R:R:W261	11.02	Yes	Yes	0	7	8
178	R:R:A294	R:R:W261	5.19	No	Yes	0	7	8
179	R:R:S297	R:R:W261	4.94	No	Yes	0	9	8
180	R:R:I266	R:R:L262	5.71	No	No	0	6	5
181	R:R:L293	R:R:P263	4.93	No	No	0	7	9
182	R:R:F264	R:R:H265	5.66	Yes	Yes	0	7	7
183	R:R:F264	R:R:F268	12.86	Yes	No	0	7	6
184	R:R:F264	R:R:I290	5.02	Yes	No	0	7	6
185	R:R:F267	R:R:F268	5.36	Yes	No	0	4	6
186	R:R:F267	R:R:Y278	16.5	Yes	No	0	4	2
187	R:R:F267	R:R:I283	7.54	Yes	No	0	4	4
188	R:R:F267	R:R:Y287	10.32	Yes	Yes	0	4	5
189	R:R:F267	R:R:I290	8.79	Yes	No	0	4	6
190	L:L:M11	R:R:F268	9.95	No	No	0	0	6
191	R:R:L270	R:R:L277	5.54	No	No	0	4	5
192	R:R:L270	R:R:Y278	5.86	No	No	0	4	2
193	R:R:P271	R:R:Y278	11.13	No	No	0	4	2
194	R:R:D276	R:R:N274	5.39	No	Yes	0	1	4
195	R:R:L277	R:R:N274	9.61	No	Yes	0	5	4
196	R:R:F282	R:R:L277	4.87	No	No	0	3	5
197	L:L:Q5	R:R:L279	7.99	No	No	0	0	2
198	R:R:F282	R:R:K280	4.96	No	No	0	3	4
199	R:R:K281	R:R:Q284	5.42	No	Yes	1	2	4
200	R:R:Q284	R:R:Q285	10.24	Yes	Yes	1	4	1
201	L:L:F7	R:R:Q284	7.03	Yes	Yes	1	0	4
202	R:R:M291	R:R:Y287	10.78	No	Yes	1	5	5
203	L:L:F7	R:R:Y287	9.28	Yes	Yes	1	0	5
204	L:L:G9	R:R:Y287	5.79	No	Yes	0	0	5
205	R:R:M291	R:R:M295	5.78	No	No	0	5	7
206	R:R:S296	R:R:Y300	6.36	No	No	0	5	5
207	R:R:I303	R:R:M299	5.83	No	No	0	7	7
208	R:R:N301	R:R:Y305	4.65	No	No	0	9	9
209	R:R:F312	R:R:Y305	19.6	Yes	No	0	9	9
210	R:R:C306	R:R:R313	5.57	No	No	0	7	8
211	R:R:N309	R:R:R311	6.03	No	No	0	8	6
212	R:R:F312	R:R:N309	9.67	Yes	No	0	9	8
213	L:L:K3	L:L:Q5	9.49	No	No	0	0	0
214	L:L:P4	L:L:Q5	6.32	No	No	0	0	0
215	L:L:F8	L:L:Q6	15.23	Yes	No	0	0	0
216	R:R:L142	R:R:T147	4.42	No	Yes	0	6	7
217	R:R:I198	R:R:K194	4.36	No	No	0	5	3
218	R:R:F257	R:R:P208	4.33	Yes	No	0	9	9
219	R:R:M249	R:R:M250	4.33	No	Yes	0	8	8
220	R:R:E78	R:R:S119	4.31	Yes	No	0	9	9
221	R:R:I134	R:R:L223	4.28	No	No	0	8	8
222	R:R:I154	R:R:N73	4.25	No	Yes	0	7	9
223	R:R:I273	R:R:N274	4.25	No	Yes	0	5	4
224	R:R:K243	R:R:L223	4.23	No	No	0	7	8
225	R:R:K317	R:R:L314	4.23	No	No	0	5	4
226	R:R:C306	R:R:F316	4.19	No	Yes	0	7	6
227	R:R:A125	R:R:F70	4.16	No	Yes	0	7	7
228	L:L:K3	L:L:Q6	4.07	No	No	0	0	0
229	R:R:G49	R:R:P302	4.06	No	No	0	8	9
230	R:R:C260	R:R:Y300	4.03	No	No	0	8	5
231	R:R:A215	R:R:Y131	4	No	Yes	0	7	8
232	R:R:H136	R:R:M132	3.94	Yes	No	0	6	5
233	R:R:F316	R:R:V53	3.93	Yes	No	0	6	8
234	R:R:R244	R:R:V240	3.92	No	No	0	5	2
235	R:R:A319	R:R:W55	3.89	No	Yes	0	4	4
236	R:R:A77	R:R:W155	3.89	No	Yes	0	8	9
237	R:R:R141	R:R:T67	3.88	Yes	No	0	5	8
238	R:R:V219	R:R:Y131	3.79	Yes	Yes	0	8	8
239	R:R:F76	R:R:M54	3.73	No	No	0	6	7
240	R:R:G166	R:R:S169	3.71	No	No	0	5	5
241	R:R:K317	R:R:R313	3.71	No	No	0	5	8
242	R:R:G220	R:R:V247	3.68	No	No	0	5	6
243	R:R:T171	R:R:W98	3.64	No	Yes	0	5	8
244	R:R:I212	R:R:Y216	3.63	No	Yes	0	8	9
245	R:R:L203	R:R:Y121	3.52	No	No	0	4	5
246	R:R:A82	R:R:S46	3.42	No	No	0	6	8
247	R:R:A75	R:R:V53	3.39	No	No	0	9	8
248	R:R:A144	R:R:V66	3.39	No	Yes	0	2	6
249	R:R:I290	R:R:P263	3.39	No	No	0	6	9
250	L:L:P4	R:R:M174	3.35	No	No	0	0	1
251	R:R:L207	R:R:P208	3.28	No	No	0	5	9
252	R:R:N189	R:R:P188	3.26	No	No	0	3	1
253	R:R:A162	R:R:I113	3.25	No	Yes	0	7	5
254	R:R:C307	R:R:K245	3.23	No	No	0	6	8
255	R:R:V43	R:R:V87	3.21	No	No	0	6	8
256	R:R:T124	R:R:V211	3.17	No	No	0	7	6
257	R:R:T171	R:R:V178	3.17	No	No	0	5	4
258	R:R:T173	R:R:V178	3.17	No	No	0	2	4
259	R:R:C260	R:R:L293	3.17	No	No	0	8	7
260	R:R:P140	R:R:Q139	3.16	No	No	0	6	4
261	R:R:A93	R:R:L288	3.15	No	No	0	5	3
262	R:R:A146	R:R:L142	3.15	No	No	0	4	6
263	R:R:I191	R:R:V195	3.07	No	No	0	1	4
264	R:R:I283	R:R:V286	3.07	No	No	0	4	5
265	R:R:H187	R:R:P185	3.05	No	No	0	2	4
266	R:R:M54	R:R:V51	3.04	No	No	0	7	4
267	R:R:I135	R:R:T222	3.04	Yes	No	0	7	5
268	R:R:M250	R:R:V246	3.04	Yes	No	0	8	7
269	R:R:L157	R:R:V153	2.98	No	No	0	4	3
270	R:R:L160	R:R:V156	2.98	No	No	0	4	3
271	R:R:L210	R:R:V211	2.98	No	No	0	3	6
272	R:R:I120	R:R:M123	2.92	No	No	0	7	8
273	R:R:K245	R:R:L308	2.82	No	No	0	8	7
274	R:R:G101	R:R:W98	2.81	No	Yes	0	8	8
275	R:R:A36	R:R:F90	2.77	No	No	0	6	6
276	R:R:H60	R:R:I56	2.65	No	No	0	5	8
277	R:R:F206	R:R:V202	2.62	No	No	0	4	4
278	R:R:A38	R:R:W292	2.59	No	No	0	4	5
279	R:R:V253	R:R:Y216	2.52	No	Yes	0	7	9
280	R:R:V254	R:R:Y216	2.52	No	Yes	0	8	9
281	R:R:K61	R:R:R64	2.48	No	No	0	6	6
282	R:R:H136	R:R:Q139	2.47	Yes	No	0	6	4
283	R:R:D310	R:R:R313	2.38	No	No	0	4	8
284	R:R:L34	R:R:W30	2.28	No	No	0	4	1
285	R:R:F110	R:R:F163	2.14	No	No	0	6	4
286	R:R:G49	R:R:V48	1.84	No	No	0	8	4
287	R:R:G213	R:R:V254	1.84	No	No	0	4	8
288	R:R:G220	R:R:V219	1.84	No	Yes	0	5	8
289	R:R:G213	R:R:T217	1.82	No	No	0	4	3
290	R:R:A114	R:R:A158	1.79	No	No	0	5	8
291	R:R:A114	R:R:A162	1.79	No	No	0	5	7
292	R:R:A118	R:R:A158	1.79	No	No	0	7	8
293	R:R:A146	R:R:S143	1.71	No	No	0	4	7
294	R:R:C152	R:R:V156	1.71	No	No	0	3	3
295	R:R:C199	R:R:V195	1.71	No	No	0	4	4
296	R:R:A82	R:R:V47	1.7	No	No	0	6	6
297	R:R:A83	R:R:V47	1.7	No	No	0	4	6
298	R:R:C255	R:R:I259	1.64	No	No	0	4	5
299	R:R:N274	R:R:P275	1.63	Yes	No	0	4	3
300	R:R:A133	R:R:I134	1.62	No	No	0	8	8
301	R:R:A115	R:R:M81	1.61	No	Yes	0	8	7
302	R:R:V44	R:R:V48	1.6	No	No	0	4	4
303	R:R:S143	R:R:T145	1.6	No	No	0	7	4
304	R:R:V149	R:R:V153	1.6	No	No	0	3	3
305	R:R:T40	R:R:V44	1.59	No	No	0	4	4
306	R:R:T45	R:R:V41	1.59	No	No	0	4	5
307	R:R:T145	R:R:V149	1.59	No	No	0	4	3
308	R:R:T256	R:R:V252	1.59	No	No	0	6	5
309	R:R:I251	R:R:V247	1.54	No	No	0	5	6
310	R:R:M299	R:R:S46	1.53	No	No	0	7	8
311	R:R:H136	R:R:P137	1.53	Yes	No	0	6	8
312	R:R:I221	R:R:T217	1.52	No	No	0	3	3
313	R:R:A242	R:R:E238	1.51	No	No	0	5	3
314	R:R:L58	R:R:V72	1.49	No	No	0	2	6
315	R:R:L157	R:R:L160	1.38	No	No	0	4	4
316	R:R:H237	R:R:V240	1.38	No	No	0	2	2
317	R:R:L138	R:R:Q139	1.33	No	No	0	6	4
318	R:R:A289	R:R:W35	1.3	No	No	0	5	4

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:F25	10.836	5	1	6
2	R:R:Q27	9.075	4	1	4
3	R:R:Q31	9.9325	4	1	2
4	R:R:W55	5.8275	4	0	4
5	R:R:V66	6.5325	4	3	6
6	R:R:F70	8.53	4	0	7
7	R:R:N73	8.25	4	0	9
8	R:R:E78	8.652	5	2	9
9	R:R:M81	4.5925	4	4	7
10	R:R:N85	7.04	5	1	6
11	R:R:N89	8.324	5	1	6
12	R:R:N96	10.4525	4	0	4
13	R:R:W98	7.88571	7	1	8
14	R:R:Y100	13.6975	4	1	7
15	R:R:Y104	11.165	4	1	5
16	R:R:H108	11.9225	4	1	5
17	R:R:I113	6.9775	4	5	5
18	R:R:Y131	8.7475	4	6	8
19	R:R:I135	9.6725	4	6	7
20	R:R:H136	4.532	5	6	6
21	R:R:R141	7.6325	4	3	5
22	R:R:T147	7.1525	4	3	7
23	R:R:W155	6.41	4	0	9
24	R:R:Q165	9.5375	4	5	6
25	R:R:R177	9.664	5	0	2
26	R:R:C180	6.15	4	1	9
27	R:R:W184	11.3525	4	0	5
28	R:R:Y196	10.112	5	0	6
29	R:R:Y205	7.7775	4	0	8
30	R:R:Y216	7.63667	6	0	9
31	R:R:V219	4.465	4	0	8
32	R:R:M250	8.155	4	0	8
33	R:R:F257	5.94	4	0	9
34	R:R:W261	6.49167	6	4	8
35	R:R:F264	8.64	4	0	7
36	R:R:H265	7.725	4	0	7
37	R:R:F267	9.702	5	0	4
38	R:R:N274	5.22	4	0	4
39	R:R:Q284	9.696	5	1	4
40	R:R:Q285	7.7225	4	1	1
41	R:R:Y287	8.862	5	1	5
42	R:R:F312	9.398	5	0	9
43	R:R:F316	5.2375	4	0	6
44	L:L:F7	10.545	4	1	0
45	L:L:F8	11.3525	4	0	0
46	L:L:L10	6.4825	4	1	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:Q284	R:R:Q285	16.9341	10.24	Yes	Yes	1	4	1
2	R:R:Q285	R:R:W35	11.6261	6.57	Yes	No	0	1	4
3	L:L:F7	R:R:Y287	53.4602	9.28	Yes	Yes	1	0	5
4	R:R:F267	R:R:Y287	83.162	10.32	Yes	Yes	0	4	5
5	R:R:F267	R:R:F268	50.0177	5.36	Yes	No	0	4	6
6	R:R:F264	R:R:F268	64.5826	12.86	Yes	No	0	7	6
7	R:R:F264	R:R:W261	100	11.02	Yes	Yes	0	7	8
8	R:R:M81	R:R:W261	96.3803	4.65	Yes	Yes	4	7	8
9	R:R:M81	R:R:T298	95.6918	6.02	Yes	No	0	7	9
10	R:R:F267	R:R:I290	44.0743	8.79	Yes	No	0	4	6
11	R:R:F264	R:R:I290	44.8033	5.02	Yes	No	0	7	6
12	R:R:E78	R:R:T298	91.0393	11.29	Yes	No	0	9	9
13	R:R:E78	R:R:N301	85.0377	11.83	Yes	No	2	9	9
14	R:R:N301	R:R:Y305	84.653	4.65	No	No	0	9	9
15	R:R:F312	R:R:Y305	24.3735	19.6	Yes	No	0	9	9
16	R:R:F312	R:R:V53	16.9924	5.24	Yes	No	0	9	8
17	R:R:F316	R:R:V53	15.0483	3.93	Yes	No	0	6	8
18	R:R:L71	R:R:Y305	64.6155	8.21	No	No	0	8	9
19	R:R:L71	R:R:N68	25.8594	5.49	No	No	0	8	8
20	R:R:N68	R:R:T65	25.9834	5.85	No	No	0	8	7
21	R:R:T65	R:R:T67	24.9962	4.71	No	No	0	7	8
22	R:R:R141	R:R:T67	23.9964	3.88	Yes	No	0	5	8
23	R:R:R141	R:R:T147	14.6864	10.35	Yes	Yes	3	5	7
24	R:R:L71	R:R:R130	45.2919	4.86	No	No	0	8	9
25	L:L:F7	R:R:N96	26.2188	10.87	Yes	Yes	0	0	4
26	R:R:N96	R:R:Y92	10.0694	11.63	Yes	No	0	4	4
27	R:R:W98	R:R:Y92	13.8688	12.54	Yes	No	0	8	4
28	R:R:N89	R:R:Y287	28.4463	8.14	Yes	Yes	1	6	5
29	L:L:L10	R:R:N89	19.8071	6.87	Yes	Yes	1	0	6
30	L:L:F8	R:R:N96	12.7398	9.67	Yes	Yes	0	0	4
31	R:R:T171	R:R:W98	12.836	3.64	No	Yes	0	5	8
32	R:R:W184	R:R:Y168	19.8982	4.82	Yes	No	0	5	5
33	R:R:I182	R:R:W184	12.0539	12.92	No	Yes	0	4	5
34	R:R:I182	R:R:Q165	12.7601	8.23	No	Yes	0	4	6
35	L:L:M11	R:R:Q165	23.8394	8.16	No	Yes	5	0	6
36	L:L:M11	R:R:F268	32.8937	9.95	No	No	0	0	6
37	R:R:W184	R:R:Y196	12.226	13.5	Yes	Yes	0	5	6
38	R:R:Q165	R:R:Y196	17.1999	13.53	Yes	Yes	0	6	6
39	R:R:F264	R:R:H265	15.18	5.66	Yes	Yes	0	7	7
40	R:R:R130	R:R:Y216	43.6972	11.32	No	Yes	0	9	9
41	R:R:V219	R:R:Y131	14.0156	3.79	Yes	Yes	0	8	8
42	R:R:M250	R:R:V219	27.1579	6.09	Yes	Yes	0	8	8
43	R:R:M250	R:R:Y216	33.7544	19.16	Yes	Yes	0	8	9
44	R:R:P185	R:R:Y168	12.3146	15.3	No	No	0	4	5
45	R:R:F267	R:R:Y278	11.697	16.5	Yes	No	0	4	2
46	R:R:L142	R:R:T147	10.806	4.42	No	Yes	0	6	7
47	L:L:F7	R:R:Q284	26.353	7.03	Yes	Yes	1	0	4

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:F25	R:R:N23	8.46	1	Yes	No	6	8	1	2
R:R:N23	R:R:R177	14.46	0	No	Yes	8	2	2	2
R:R:F25	R:R:Q24	14.05	1	Yes	No	6	3	1	2
R:R:K281	R:R:Q24	5.42	1	No	No	2	3	2	2
R:R:F25	R:R:K281	4.96	1	Yes	No	6	2	1	2
R:R:F25	R:R:Q284	11.71	1	Yes	Yes	6	4	1	1
L:L:F7	R:R:F25	15	1	Yes	Yes	0	6	0	1
R:R:Q27	R:R:Q284	14.08	1	Yes	Yes	4	4	2	1
R:R:Q27	R:R:Q285	7.68	1	Yes	Yes	4	1	2	2
R:R:N85	R:R:N89	5.45	1	Yes	Yes	6	6	1	1
R:R:H108	R:R:N85	7.65	1	Yes	Yes	5	6	2	1
R:R:N85	R:R:P112	4.89	1	Yes	No	6	6	1	2
R:R:M295	R:R:N85	7.01	0	No	Yes	7	6	2	1
L:L:?12	R:R:N85	10.2	0	No	Yes	0	6	0	1
R:R:H108	R:R:N89	12.75	1	Yes	Yes	5	6	2	1
R:R:N89	R:R:Y287	8.14	1	Yes	Yes	6	5	1	1
R:R:M291	R:R:N89	8.41	1	No	Yes	5	6	2	1
L:L:L10	R:R:N89	6.87	1	Yes	Yes	0	6	0	1
R:R:N96	R:R:Y92	11.63	0	Yes	No	4	4	1	1
R:R:W98	R:R:Y92	12.54	1	Yes	No	8	4	2	1
L:L:L10	R:R:Y92	4.69	1	Yes	No	0	4	0	1
R:R:N96	R:R:R177	9.64	0	Yes	Yes	4	2	1	2
L:L:F7	R:R:N96	10.87	1	Yes	Yes	0	4	0	1
L:L:F8	R:R:N96	9.67	0	Yes	Yes	0	4	0	1
R:R:C105	R:R:W98	5.22	1	No	Yes	9	8	2	2
R:R:C180	R:R:W98	7.84	1	Yes	Yes	9	8	1	2
R:R:C105	R:R:C180	7.28	1	No	Yes	9	9	2	1
R:R:H108	R:R:P112	10.68	1	Yes	No	5	6	2	2
R:R:N109	R:R:S169	5.96	1	No	No	5	5	1	2
R:R:C180	R:R:N109	4.72	1	Yes	No	9	5	1	1
L:L:L10	R:R:N109	9.61	1	Yes	No	0	5	0	1
R:R:I113	R:R:Q165	8.23	5	Yes	Yes	5	6	1	1
L:L:M11	R:R:I113	5.83	5	No	Yes	0	5	0	1
L:L:?12	R:R:I113	10.6	0	No	Yes	0	5	0	1
R:R:I182	R:R:Q165	8.23	0	No	Yes	4	6	2	1
R:R:Q165	R:R:Y196	13.53	5	Yes	Yes	6	6	1	2
L:L:M11	R:R:Q165	8.16	5	No	Yes	0	6	0	1
R:R:E172	R:R:M174	5.41	0	No	No	3	1	2	1
R:R:M174	R:R:P175	5.03	0	No	No	1	2	1	2
R:R:R177	R:R:V179	6.54	0	Yes	No	2	3	2	1
L:L:F8	R:R:V179	11.8	0	Yes	No	0	3	0	1
L:L:L10	R:R:C180	4.76	1	Yes	Yes	0	9	0	1
L:L:F8	R:R:M181	8.71	0	Yes	No	0	4	0	1
R:R:F264	R:R:F268	12.86	0	Yes	No	7	6	2	1
R:R:F267	R:R:F268	5.36	0	Yes	No	4	6	2	1
R:R:F267	R:R:Y287	10.32	0	Yes	Yes	4	5	2	1
L:L:M11	R:R:F268	9.95	5	No	No	0	6	0	1
L:L:Q5	R:R:L279	7.99	0	No	No	0	2	0	1
R:R:K281	R:R:Q284	5.42	1	No	Yes	2	4	2	1
R:R:Q284	R:R:Q285	10.24	1	Yes	Yes	4	1	1	2
L:L:F7	R:R:Q284	7.03	1	Yes	Yes	0	4	0	1
R:R:M291	R:R:Y287	10.78	1	No	Yes	5	5	2	1
L:L:F7	R:R:Y287	9.28	1	Yes	Yes	0	5	0	1
L:L:G9	R:R:Y287	5.79	0	No	Yes	0	5	0	1
R:R:M291	R:R:M295	5.78	1	No	No	5	7	2	2
L:L:P4	R:R:M174	3.35	0	No	No	0	1	0	1
R:R:A162	R:R:I113	3.25	0	No	Yes	7	5	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	7P02_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	4.58
Number of Linked Nodes	288
Number of Links	318
Number of Hubs	46
Number of Links mediated by Hubs	160
Number of Communities	6
Number of Nodes involved in Communities	39
Number of Links involved in Communities	52

Path Summary
Number Of Nodes in MetaPath	48
Number Of Links MetaPath	47
Number of Shortest Paths	68229
Length Of Smallest Path	3
Average Path Length	15.3057
Length of Longest Path	35
Minimum Path Strength	1.595
Average Path Strength	8.05775
Maximum Path Strength	22.175
Minimum Path Correlation	0.7
Average Path Correlation	0.926466
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	3.84615
Average % Of Corr. Nodes	43.3933
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	47.533
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	NH2
PDB Residues	L:L:?12
Environment Details	Open EMBL-EBI Page
Code	NH2
Name	AMINO GROUP
Synonyms
Identifier
Formula	H2 N
Molecular Weight	16.023
SMILES
PubChem	123329
Formal Charge	0
Total Atoms	3
Total Chiral Atoms	0
Total Bonds	2
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P25103
Sequence	>7P02_nogp_Chain_R P N Q F V Q P A W Q I V L W A A A Y T V I V V T S V V G N V V V M W I I L A H K R M R T V T N Y F L V N L A F A E A S M A A F N T V V N F T Y A V H N E W Y Y G L F Y C K F H N F F P I A A V F A S I Y S M T A V A F D R Y M A I I H P L Q P R L S A T A T K V V I C V I W V L A L L L A F P Q G Y Y S T T E T M P S R V V C M I E W P E H P N K I Y E K V Y H I C V T V L I Y F L P L L V I G Y A Y T V V G I T L W A H E Q V S A K R K V V K M M I V V V C T F A I C W L P F H I F F L L P Y I N P D L Y L K K F I Q Q V Y L A I M W L A M S S T M Y N P I I Y C C L N D R F R L G F K H A Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8U26	A	Peptide	Tachykinin	NK₁	Homo sapiens	Protachykinin-1	-	Gs/β1/γ2	2.5	2023-11-15	10.1038/s41592-023-02082-9
	8U26 (No Gprot)	A	Peptide	Tachykinin	NK₁	Homo sapiens	Protachykinin-1	-		2.5	2023-11-15	10.1038/s41592-023-02082-9
	7P00	A	Peptide	Tachykinin	NK₁	Homo sapiens	Substance-P	-	chim(NtGi1-Gs-CtGq)/β1/γ2	2.71	2021-12-15	10.1126/sciadv.abk2872
	7P00 (No Gprot)	A	Peptide	Tachykinin	NK₁	Homo sapiens	Substance-P	-		2.71	2021-12-15	10.1126/sciadv.abk2872
	7P02	A	Peptide	Tachykinin	NK₁	Homo sapiens	Protachykinin-1	-	chim(NtGi1-Gs)/β1/γ2	2.87	2021-12-15	10.1126/sciadv.abk2872
	7P02 (No Gprot)	A	Peptide	Tachykinin	NK₁	Homo sapiens	Protachykinin-1	-		2.87	2021-12-15	10.1126/sciadv.abk2872
	7RMI	A	Peptide	Tachykinin	NK₁	Homo sapiens	Substance-P	-	chim(Gs-CtGq)/β1/γ2	3.2	2021-11-03	10.1038/s41589-021-00890-8
	7RMI (No Gprot)	A	Peptide	Tachykinin	NK₁	Homo sapiens	Substance-P	-		3.2	2021-11-03	10.1038/s41589-021-00890-8
	7RMG	A	Peptide	Tachykinin	NK₁	Homo sapiens	Substance-P	-	chim(Gs-CtGq)/β1/γ2	3	2021-11-03	10.1038/s41589-021-00890-8
	7RMG (No Gprot)	A	Peptide	Tachykinin	NK₁	Homo sapiens	Substance-P	-		3	2021-11-03	10.1038/s41589-021-00890-8
	7RMH	A	Peptide	Tachykinin	NK₁	Homo sapiens	Substance-P	-	Gs/β1/γ2	3.1	2021-11-03	10.1038/s41589-021-00890-8
	7RMH (No Gprot)	A	Peptide	Tachykinin	NK₁	Homo sapiens	Substance-P	-		3.1	2021-11-03	10.1038/s41589-021-00890-8
	6J21	A	Peptide	Tachykinin	NK₁	Homo sapiens	Aprepitant	-	-	3.2	2019-03-06	10.1038/s41467-019-08568-5
	6J20	A	Peptide	Tachykinin	NK₁	Homo sapiens	Aprepitant	-	-	2.7	2019-03-06	10.1038/s41467-019-08568-5
	6HLP	A	Peptide	Tachykinin	NK₁	Homo sapiens	Netupitant	-	-	2.2	2019-01-16	10.1038/s41467-018-07939-8
	6HLO	A	Peptide	Tachykinin	NK₁	Homo sapiens	Aprepitant	-	-	2.4	2019-01-16	10.1038/s41467-018-07939-8
	6HLL	A	Peptide	Tachykinin	NK₁	Homo sapiens	CP99994	-	-	3.27	2019-01-16	10.1038/s41467-018-07939-8
	6E59	A	Peptide	Tachykinin	NK₁	Homo sapiens	L-760735	-	-	3.4	2018-12-12	10.1073/pnas.1812717115

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 7P02_nogp.zip

You can click to copy the link of this page to easily come back here later

or use this QR code to link and share this page.

You can also read or download a guide explaining the meaning of all files and numerical data.