psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:F5	R:R:L66	3.65	No	No	0	4	5
2	R:R:F5	R:R:S67	5.28	No	No	0	4	5
3	R:R:F7	R:R:Q65	11.71	No	No	0	5	4
4	R:R:F7	R:R:R262	6.41	No	No	0	5	3
5	R:R:F7	R:R:L266	3.65	No	No	0	5	5
6	R:R:I10	R:R:L266	4.28	No	No	0	4	5
7	R:R:I58	R:R:L11	4.28	No	No	0	7	6
8	R:R:I18	R:R:L14	5.71	No	No	0	8	5
9	R:R:L14	R:R:V269	4.47	No	No	0	5	6
10	R:R:A15	R:R:I58	3.25	No	No	0	6	7
11	R:R:L17	R:R:L273	5.54	No	No	0	4	5
12	R:R:I18	R:R:S272	4.64	No	No	0	8	9
13	R:R:I18	R:R:L273	4.28	No	No	0	8	5
14	R:R:G55	R:R:I19	3.53	No	No	0	8	6
15	R:R:P276	R:R:T21	3.5	Yes	No	0	9	8
16	R:R:D51	R:R:N22	13.46	Yes	No	2	9	9
17	R:R:N22	R:R:P276	9.77	No	Yes	2	9	9
18	R:R:A280	R:R:V25	3.39	No	No	0	8	9
19	R:R:L45	R:R:V29	7.45	No	No	0	6	8
20	R:R:L30	R:R:L45	5.54	No	No	0	3	6
21	R:R:L31	R:R:Q289	5.32	No	Yes	0	5	7
22	R:R:L32	R:R:N36	4.12	Yes	No	3	7	9
23	R:R:E285	R:R:L32	3.98	No	Yes	3	6	7
24	R:R:L32	R:R:Q289	5.32	Yes	Yes	0	7	7
25	R:R:K35	R:R:N36	5.6	No	No	0	6	9
26	R:R:E285	R:R:N36	5.26	No	No	3	6	9
27	R:R:M117	R:R:V39	4.56	No	No	0	7	5
28	R:R:F43	R:R:L98	7.31	Yes	No	0	8	7
29	R:R:F43	R:R:I99	3.77	Yes	No	0	8	9
30	R:R:D102	R:R:F43	8.36	No	Yes	0	9	8
31	R:R:F43	R:R:I126	5.02	Yes	No	0	8	7
32	R:R:N46	R:R:T95	10.24	Yes	No	0	9	8
33	R:R:I126	R:R:N46	7.08	No	Yes	0	7	9
34	R:R:L129	R:R:N46	4.12	No	Yes	4	6	9
35	R:R:N46	R:R:W130	9.04	Yes	Yes	4	9	9
36	R:R:L47	R:R:T95	5.9	No	No	0	9	8
37	R:R:L47	R:R:N275	9.61	No	Yes	0	9	9
38	R:R:L47	R:R:Y279	3.52	No	Yes	0	9	9
39	R:R:D51	R:R:S92	4.42	Yes	No	0	9	9
40	R:R:D51	R:R:S272	8.83	Yes	No	0	9	9
41	R:R:D51	R:R:N275	4.04	Yes	Yes	0	9	9
42	R:R:D51	R:R:P276	3.22	Yes	Yes	2	9	9
43	R:R:L53	R:R:W130	3.42	No	Yes	0	8	9
44	R:R:G55	R:R:I54	3.53	No	No	0	8	8
45	R:R:I54	R:R:S88	6.19	No	No	0	8	6
46	R:R:I54	R:R:S272	9.29	No	No	0	8	9
47	L:L:?1	R:R:L61	4.4	Yes	No	0	0	5
48	R:R:D64	R:R:T63	5.78	No	No	0	4	5
49	R:R:D64	R:R:R81	9.53	No	No	0	4	6
50	R:R:P72	R:R:R71	7.21	No	No	0	3	6
51	R:R:L77	R:R:T73	4.42	No	No	0	4	5
52	R:R:K152	R:R:K75	10.06	No	No	0	1	3
53	R:R:C78	R:R:M82	3.24	No	No	0	9	5
54	R:R:C155	R:R:C78	7.28	No	No	0	9	9
55	R:R:S79	R:R:V160	6.46	No	No	0	4	5
56	R:R:C155	R:R:R81	5.57	No	No	0	9	6
57	R:R:F157	R:R:M82	6.22	Yes	No	1	4	5
58	R:R:F161	R:R:M82	6.22	Yes	No	1	4	5
59	R:R:A83	R:R:F138	8.32	No	No	0	6	4
60	R:R:F84	R:R:Y134	7.22	No	No	0	3	4
61	L:L:?1	R:R:V85	5.68	Yes	No	0	0	7
62	R:R:G137	R:R:T86	3.64	No	No	0	7	5
63	L:L:?1	R:R:T86	6.56	Yes	No	0	0	5
64	R:R:S87	R:R:Y134	12.72	No	No	0	5	4
65	R:R:G137	R:R:S87	3.71	No	No	0	7	5
66	L:L:?1	R:R:A89	5	Yes	No	0	0	6
67	R:R:A90	R:R:S133	3.42	No	No	0	7	8
68	R:R:A90	R:R:I136	3.25	No	No	0	7	6
69	R:R:A91	R:R:W130	3.89	No	Yes	0	7	9
70	R:R:A91	R:R:S133	3.42	No	No	0	7	8
71	L:L:?1	R:R:V93	6.63	Yes	No	0	0	7
72	R:R:F234	R:R:V96	5.24	Yes	No	0	9	9
73	R:R:N275	R:R:V96	4.43	Yes	No	0	9	9
74	R:R:V96	R:R:Y279	3.79	No	Yes	0	9	9
75	R:R:A177	R:R:M97	4.83	No	No	0	8	7
76	R:R:F181	R:R:M97	3.73	Yes	No	0	8	7
77	R:R:I99	R:R:Y279	3.63	No	Yes	0	9	9
78	R:R:F181	R:R:T100	9.08	Yes	No	5	8	8
79	R:R:F184	R:R:T100	3.89	Yes	No	0	6	8
80	R:R:T100	R:R:Y185	8.74	No	Yes	5	8	9
81	R:R:F101	R:R:L105	7.31	No	No	0	5	5
82	R:R:F101	R:R:F184	6.43	No	Yes	0	5	6
83	R:R:D102	R:R:Y113	8.05	No	No	0	9	9
84	R:R:R103	R:R:Y185	5.14	No	Yes	0	9	9
85	R:R:R103	R:R:Y279	5.14	No	Yes	0	9	9
86	R:R:K108	R:R:Y104	15.53	No	Yes	6	6	8
87	R:R:F184	R:R:Y104	17.54	Yes	Yes	0	6	8
88	R:R:D187	R:R:Y104	10.34	No	Yes	6	5	8
89	R:R:M188	R:R:Y104	3.59	No	Yes	0	9	8
90	R:R:A106	R:R:Y113	6.67	No	No	0	9	9
91	R:R:D187	R:R:K108	4.15	No	No	6	5	6
92	R:R:Q109	R:R:R112	10.51	No	No	0	5	5
93	R:R:M117	R:R:Y113	13.17	No	No	0	7	9
94	R:R:G119	R:R:S118	3.71	No	No	0	1	8
95	R:R:L129	R:R:W130	3.42	No	Yes	4	6	9
96	R:R:W130	R:R:Y134	5.79	Yes	No	0	9	4
97	R:R:F138	R:R:L141	3.65	No	No	0	4	6
98	R:R:L139	R:R:P140	4.93	No	Yes	0	4	5
99	R:R:I143	R:R:L139	4.28	No	No	0	4	4
100	R:R:F146	R:R:P140	4.33	No	Yes	1	2	5
101	R:R:F161	R:R:P140	10.11	Yes	Yes	1	4	5
102	R:R:F165	R:R:P140	11.56	No	Yes	1	6	5
103	R:R:I143	R:R:P144	3.39	No	No	0	4	2
104	R:R:F146	R:R:F165	8.57	No	No	1	2	6
105	R:R:H162	R:R:Q148	6.18	No	No	0	5	4
106	R:R:A159	R:R:S156	3.42	No	No	0	4	4
107	R:R:F157	R:R:F158	18.22	Yes	Yes	1	4	3
108	R:R:F157	R:R:F161	9.65	Yes	Yes	1	4	4
109	R:R:E261	R:R:F157	9.33	No	Yes	1	4	4
110	L:L:?1	R:R:F157	20.12	Yes	Yes	1	0	4
111	R:R:F158	R:R:V166	3.93	Yes	No	0	3	6
112	R:R:F158	R:R:L260	7.31	Yes	Yes	0	3	4
113	R:R:E261	R:R:F158	8.16	No	Yes	1	4	3
114	R:R:H162	R:R:P163	15.25	No	No	0	5	3
115	R:R:H162	R:R:H164	20.3	No	No	0	5	2
116	R:R:P163	R:R:V249	3.53	No	No	0	3	4
117	R:R:P163	R:R:Y257	9.74	No	No	0	3	4
118	R:R:H164	R:R:V249	4.15	No	No	0	2	4
119	R:R:F165	R:R:L169	6.09	No	No	0	6	6
120	R:R:F241	R:R:V166	5.24	Yes	No	0	6	6
121	L:L:?1	R:R:L169	4.4	Yes	No	0	0	6
122	R:R:F175	R:R:S170	6.61	No	No	0	5	6
123	R:R:L242	R:R:S170	6.01	No	No	0	6	6
124	R:R:I246	R:R:S170	6.19	No	No	0	5	6
125	R:R:F174	R:R:F234	3.22	No	Yes	0	8	9
126	R:R:F174	R:R:T239	3.89	No	No	0	8	4
127	R:R:F174	R:R:L242	6.09	No	No	0	8	6
128	R:R:F181	R:R:Y185	8.25	Yes	Yes	5	8	9
129	R:R:F181	R:R:I231	3.77	Yes	Yes	0	8	7
130	R:R:F181	R:R:F234	20.36	Yes	Yes	0	8	9
131	R:R:I231	R:R:V182	4.61	Yes	No	0	7	5
132	R:R:F183	R:R:F184	5.36	No	Yes	0	3	6
133	R:R:M188	R:R:Y185	4.79	No	Yes	0	9	9
134	R:R:L230	R:R:Y185	9.38	No	Yes	0	8	9
135	R:R:L189	R:R:L224	5.54	No	No	0	7	7
136	R:R:K190	R:R:M194	8.64	No	No	0	3	4
137	R:R:Q197	R:R:R200	11.68	No	No	0	5	4
138	R:R:H204	R:R:M208	3.94	No	No	0	4	2
139	R:R:A207	R:R:Y212	4	No	No	0	1	1
140	R:R:F221	R:R:L224	4.87	No	No	0	4	7
141	R:R:T226	R:R:W282	3.64	No	No	0	8	7
142	R:R:V229	R:R:W282	6.13	No	No	0	7	7
143	R:R:L230	R:R:Y279	3.52	No	Yes	0	8	9
144	R:R:C237	R:R:N271	12.6	No	No	0	7	9
145	R:R:F241	R:R:W238	6.01	Yes	Yes	1	6	8
146	R:R:G268	R:R:W238	9.85	No	Yes	0	7	8
147	R:R:N271	R:R:W238	3.39	No	Yes	0	9	8
148	L:L:?1	R:R:W238	10.13	Yes	Yes	1	0	8
149	R:R:P240	R:R:T239	5.25	No	No	0	9	4
150	R:R:L267	R:R:P240	4.93	No	No	0	7	9
151	R:R:F241	R:R:L260	4.87	Yes	Yes	0	6	4
152	L:L:?1	R:R:F241	6.19	Yes	Yes	1	0	6
153	R:R:L256	R:R:T244	5.9	No	Yes	0	5	4
154	R:R:L260	R:R:T244	7.37	Yes	Yes	0	4	4
155	R:R:L264	R:R:T244	4.42	No	Yes	0	4	4
156	R:R:G245	R:R:L260	3.42	No	Yes	0	6	4
157	R:R:L256	R:R:Q248	7.99	No	No	0	5	3
158	R:R:Q248	R:R:Y257	18.04	No	No	0	3	4
159	R:R:E253	R:R:H255	4.92	No	No	0	2	2
160	R:R:C254	R:R:Y257	8.06	No	No	0	4	4
161	R:R:H255	R:R:L258	3.86	No	No	0	2	1
162	R:R:L258	R:R:R262	4.86	No	No	0	1	3
163	R:R:V259	R:R:Y263	3.79	No	No	0	1	4
164	R:R:L264	R:R:V259	4.47	No	No	0	4	1
165	L:L:?1	R:R:E261	11.79	Yes	No	1	0	4
166	R:R:V269	R:R:W265	8.58	No	No	0	6	3
167	L:L:?1	R:R:W265	26.05	Yes	No	0	0	3
168	R:R:N271	R:R:N275	5.45	No	Yes	0	9	9
169	R:R:I278	R:R:Y279	3.63	No	Yes	0	8	9
170	R:R:R287	R:R:Y281	7.2	No	No	0	8	5
171	R:R:Q283	R:R:V286	5.73	No	No	0	8	9
172	R:R:R287	R:R:Y291	8.23	No	No	0	8	2
173	R:R:M293	R:R:Q289	8.16	No	Yes	0	5	7
174	R:R:A294	R:R:K298	4.82	No	No	0	6	4
175	R:R:T44	R:R:V29	3.17	No	No	0	7	8
176	R:R:C125	R:R:L98	3.17	No	No	0	6	7
177	R:R:C171	R:R:L167	3.17	No	No	0	4	5
178	R:R:T23	R:R:T52	3.14	No	No	0	5	6
179	R:R:I278	R:R:S233	3.1	No	No	0	8	7
180	R:R:R262	R:R:Y263	3.09	No	No	0	3	4
181	R:R:I33	R:R:V29	3.07	No	No	0	7	8
182	R:R:I231	R:R:V227	3.07	Yes	No	0	7	8
183	R:R:M117	R:R:V121	3.04	No	No	0	7	6
184	R:R:K152	R:R:V160	3.04	No	No	0	1	5
185	R:R:A28	R:R:Q289	3.03	No	Yes	0	7	7
186	R:R:L141	R:R:S79	3	No	No	0	6	4
187	R:R:L94	R:R:S133	3	No	No	0	5	8
188	R:R:L274	R:R:S233	3	No	No	0	5	7
189	R:R:L31	R:R:V27	2.98	No	No	0	5	5
190	R:R:L167	R:R:V249	2.98	No	No	0	5	4
191	R:R:L189	R:R:V227	2.98	No	No	0	7	8
192	R:R:L80	R:R:T76	2.95	No	No	0	5	2
193	R:R:I107	R:R:I191	2.94	No	No	0	8	6
194	R:R:I107	R:R:M188	2.92	No	No	0	8	9
195	R:R:D64	R:R:T73	2.89	No	No	0	4	5
196	R:R:I33	R:R:L41	2.85	No	No	0	7	9
197	R:R:Q74	R:R:T76	2.83	No	No	0	7	2
198	R:R:L290	R:R:M293	2.83	No	No	0	5	5
199	R:R:K284	R:R:L288	2.82	No	No	0	5	4
200	R:R:L32	R:R:L41	2.77	Yes	No	0	7	9
201	R:R:A122	R:R:F43	2.77	No	Yes	0	6	8
202	R:R:A57	R:R:F84	2.77	No	No	0	4	3
203	R:R:L62	R:R:L66	2.77	No	No	0	6	5
204	R:R:H195	R:R:I191	2.65	No	No	0	8	6
205	R:R:F161	R:R:V160	2.62	Yes	No	0	4	5
206	R:R:F146	R:R:T168	2.59	No	No	0	2	4
207	R:R:F175	R:R:M178	2.49	No	No	0	5	5
208	R:R:F234	R:R:M178	2.49	Yes	No	0	9	5
209	R:R:K284	R:R:R287	2.48	No	No	0	5	8
210	R:R:F138	R:R:L80	2.44	No	No	0	4	5
211	R:R:I58	R:R:W265	2.35	No	No	0	7	3
212	L:L:?1	R:R:G173	2.17	Yes	No	0	0	6
213	R:R:G210	R:R:G211	2.11	No	No	0	1	3
214	R:R:G153	R:R:P72	2.03	No	No	0	3	3
215	R:R:A122	R:R:G119	1.95	No	No	0	6	1
216	R:R:A122	R:R:G123	1.95	No	No	0	6	1
217	R:R:A127	R:R:G128	1.95	No	No	0	3	3
218	R:R:A235	R:R:G232	1.95	No	No	0	6	5
219	R:R:A26	R:R:A48	1.79	No	No	0	7	9
220	R:R:A192	R:R:A223	1.79	No	No	0	8	8
221	R:R:P69	R:R:S68	1.78	No	No	0	5	4
222	R:R:P276	R:R:V25	1.77	Yes	No	0	9	9
223	R:R:G232	R:R:I231	1.76	No	Yes	0	5	7
224	R:R:A15	R:R:S59	1.71	No	No	0	6	7
225	R:R:A50	R:R:S92	1.71	No	No	0	8	9
226	R:R:G142	R:R:L141	1.71	No	No	0	5	6
227	R:R:C171	R:R:V172	1.71	No	No	0	4	4
228	R:R:C186	R:R:V182	1.71	No	No	0	3	5
229	R:R:C251	R:R:V247	1.71	No	No	0	4	4
230	R:R:G296	R:R:L295	1.71	No	No	0	4	3
231	R:R:A48	R:R:V25	1.7	No	No	0	9	9
232	R:R:A280	R:R:V286	1.7	No	No	0	8	9
233	R:R:A280	R:R:T44	1.68	No	No	0	8	7
234	R:R:A150	R:R:T149	1.68	No	No	0	2	1
235	R:R:C42	R:R:I126	1.64	No	No	0	4	7
236	R:R:T226	R:R:V227	1.59	No	No	0	8	8
237	R:R:C237	R:R:L236	1.59	No	No	0	7	4
238	R:R:A12	R:R:L62	1.58	No	No	0	4	6
239	R:R:P110	R:R:Q109	1.58	No	No	0	8	5
240	R:R:A223	R:R:L189	1.58	No	No	0	8	7
241	R:R:I10	R:R:S6	1.55	No	No	0	4	2
242	R:R:I10	R:R:V9	1.54	No	No	0	4	5
243	R:R:I136	R:R:V132	1.54	No	No	0	6	3
244	R:R:M194	R:R:S193	1.53	No	No	0	4	6
245	R:R:I19	R:R:T23	1.52	No	No	0	6	5
246	R:R:I243	R:R:T244	1.52	No	Yes	0	5	4
247	R:R:C251	R:R:E253	1.52	No	No	0	4	2
248	R:R:A207	R:R:E203	1.51	No	No	0	1	3
249	R:R:L53	R:R:V49	1.49	No	No	0	8	6
250	R:R:L24	R:R:T23	1.47	No	No	0	8	5
251	R:R:D102	R:R:S40	1.47	No	No	0	9	8
252	R:R:I116	R:R:K115	1.45	No	No	0	5	4
253	R:R:G211	R:R:Y212	1.45	No	No	0	3	1
254	R:R:F175	R:R:P176	1.44	No	No	0	5	5
255	R:R:I278	R:R:L277	1.43	No	No	0	8	6
256	R:R:L180	R:R:M97	1.41	No	No	0	5	7
257	R:R:D187	R:R:K190	1.38	No	No	0	5	3
258	R:R:L105	R:R:Q109	1.33	No	No	0	5	5
259	R:R:R200	R:R:S196	1.32	No	No	0	4	5
260	R:R:H195	R:R:Q198	1.24	No	No	0	8	5
261	R:R:W282	R:R:Y281	0.96	No	No	0	7	5
262	L:L:?1	R:R:S156	0.95	Yes	No	0	0	4

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:L32	4.0475	4	3	7
2	R:R:F43	5.446	5	0	8
3	R:R:N46	7.62	4	4	9
4	R:R:D51	6.794	5	2	9
5	R:R:Y104	11.75	4	6	8
6	R:R:W130	5.112	5	4	9
7	R:R:P140	7.7325	4	1	5
8	R:R:F157	12.708	5	1	4
9	R:R:F158	9.405	4	1	3
10	R:R:F161	7.15	4	1	4
11	R:R:F181	9.038	5	5	8
12	R:R:F184	8.305	4	0	6
13	R:R:Y185	7.26	5	5	9
14	R:R:I231	3.3025	4	0	7
15	R:R:F234	7.8275	4	0	9
16	R:R:W238	7.345	4	1	8
17	R:R:F241	5.5775	4	1	6
18	R:R:T244	4.8025	4	0	4
19	R:R:L260	5.7425	4	0	4
20	R:R:N275	5.8825	4	0	9
21	R:R:P276	4.565	4	2	9
22	R:R:Y279	3.87167	6	0	9
23	R:R:Q289	5.4575	4	0	7
24	L:L:?1	8.46692	13	1	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:R262	R:R:Y263	19.1407	3.09	No	No	0	3	4
2	R:R:V259	R:R:Y263	20.6654	3.79	No	No	0	1	4
3	R:R:L264	R:R:V259	22.1793	4.47	No	No	0	4	1
4	R:R:L264	R:R:T244	23.6822	4.42	No	Yes	0	4	4
5	R:R:L260	R:R:T244	44.9194	7.37	Yes	Yes	0	4	4
6	R:R:F241	R:R:L260	43.4437	4.87	Yes	Yes	0	6	4
7	L:L:?1	R:R:W265	13.276	26.05	Yes	No	0	0	3
8	R:R:F241	R:R:W238	39.7789	6.01	Yes	Yes	1	6	8
9	R:R:N271	R:R:W238	98.056	3.39	No	Yes	0	9	8
10	R:R:N271	R:R:N275	100	5.45	No	Yes	0	9	9
11	R:R:D51	R:R:N275	57.0627	4.04	Yes	Yes	0	9	9
12	R:R:D51	R:R:S272	18.9447	8.83	Yes	No	0	9	9
13	R:R:I54	R:R:S272	13.2978	9.29	No	No	0	8	9
14	R:R:D51	R:R:P276	37.7641	3.22	Yes	Yes	2	9	9
15	R:R:A280	R:R:V25	30.5162	3.39	No	No	0	8	9
16	R:R:P276	R:R:V25	34.976	1.77	Yes	No	0	9	9
17	R:R:A280	R:R:T44	25.9584	1.68	No	No	0	8	7
18	R:R:T44	R:R:V29	24.4173	3.17	No	No	0	7	8
19	R:R:I33	R:R:V29	19.7288	3.07	No	No	0	7	8
20	R:R:I33	R:R:L41	18.1442	2.85	No	No	0	7	9
21	R:R:L32	R:R:L41	16.5487	2.77	Yes	No	0	7	9
22	R:R:L32	R:R:Q289	10.0577	5.32	Yes	Yes	0	7	7
23	R:R:L47	R:R:N275	44.3095	9.61	No	Yes	0	9	9
24	R:R:L47	R:R:Y279	45.9431	3.52	No	Yes	0	9	9
25	R:R:I99	R:R:Y279	33.8543	3.63	No	Yes	0	9	9
26	R:R:F43	R:R:I99	31.8504	3.77	Yes	No	0	8	9
27	R:R:D102	R:R:F43	16.1947	8.36	No	Yes	0	9	8
28	R:R:D102	R:R:Y113	11.6206	8.05	No	No	0	9	9
29	R:R:N275	R:R:V96	83.5929	4.43	Yes	No	0	9	9
30	R:R:V96	R:R:Y279	41.7937	3.79	No	Yes	0	9	9
31	R:R:L47	R:R:T95	21.3189	5.9	No	No	0	9	8
32	R:R:N46	R:R:T95	19.8486	10.24	Yes	No	0	9	8
33	L:L:?1	R:R:T86	10.7656	6.56	Yes	No	0	0	5
34	R:R:W130	R:R:Y134	11.1468	5.79	Yes	No	0	9	4
35	R:R:C78	R:R:M82	11.6206	3.24	No	No	0	9	5
36	R:R:F157	R:R:M82	12.4102	6.22	Yes	No	1	4	5
37	R:R:F157	R:R:F161	25.2069	9.65	Yes	Yes	1	4	4
38	R:R:F161	R:R:V160	18.0843	2.62	Yes	No	0	4	5
39	R:R:S79	R:R:V160	13.2814	6.46	No	No	0	4	5
40	R:R:L141	R:R:S79	11.6587	3	No	No	0	6	4
41	R:R:A91	R:R:W130	10.7765	3.89	No	Yes	0	7	9
42	R:R:F234	R:R:V96	57.2261	5.24	Yes	No	0	9	9
43	R:R:F181	R:R:F234	47.0322	20.36	Yes	Yes	0	8	9
44	R:R:F181	R:R:T100	13.1072	9.08	Yes	No	5	8	8
45	R:R:F184	R:R:T100	15.3289	3.89	Yes	No	0	6	8
46	R:R:R103	R:R:Y279	28.6702	5.14	No	Yes	0	9	9
47	R:R:R103	R:R:Y185	27.2108	5.14	No	Yes	0	9	9
48	R:R:L230	R:R:Y279	28.6702	3.52	No	Yes	0	8	9
49	R:R:L230	R:R:Y185	27.2108	9.38	No	Yes	0	8	9
50	R:R:F181	R:R:Y185	21.3951	8.25	Yes	Yes	5	8	9
51	R:R:M188	R:R:Y185	47.7619	4.79	No	Yes	0	9	9
52	R:R:M188	R:R:Y104	26.3886	3.59	No	Yes	0	9	8
53	R:R:D187	R:R:Y104	21.406	10.34	No	Yes	6	5	8
54	R:R:F165	R:R:L169	10.1231	6.09	No	No	0	6	6
55	L:L:?1	R:R:L169	11.6097	4.4	Yes	No	0	0	6
56	R:R:L256	R:R:T244	20.6654	5.9	No	Yes	0	5	4
57	R:R:L256	R:R:Q248	19.1407	7.99	No	No	0	5	3
58	R:R:Q248	R:R:Y257	17.6051	18.04	No	No	0	3	4
59	R:R:P163	R:R:Y257	14.5012	9.74	No	No	0	3	4
60	R:R:F181	R:R:I231	32.689	3.77	Yes	Yes	0	8	7
61	R:R:I231	R:R:V227	24.4663	3.07	Yes	No	0	7	8
62	R:R:D187	R:R:K190	16.0858	1.38	No	No	0	5	3
63	R:R:K190	R:R:M194	10.733	8.64	No	No	0	3	4
64	R:R:T226	R:R:V227	14.2398	1.59	No	No	0	8	8
65	R:R:T226	R:R:W282	12.4973	3.64	No	No	0	8	7
66	R:R:I107	R:R:M188	17.6813	2.92	No	No	0	8	9
67	R:R:I107	R:R:I191	13.276	2.94	No	No	0	8	6
68	L:L:?1	R:R:W238	57.0301	10.13	Yes	Yes	1	0	8
69	R:R:N46	R:R:W130	17.5833	9.04	Yes	Yes	4	9	9
70	L:L:?1	R:R:F157	35.1721	20.12	Yes	Yes	1	0	4

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?1	R:R:L61	4.4	1	Yes	No	0	5	0	1
R:R:F157	R:R:M82	6.22	1	Yes	No	4	5	1	2
R:R:F161	R:R:M82	6.22	1	Yes	No	4	5	2	2
L:L:?1	R:R:V85	5.68	1	Yes	No	0	7	0	1
R:R:G137	R:R:T86	3.64	0	No	No	7	5	2	1
L:L:?1	R:R:T86	6.56	1	Yes	No	0	5	0	1
L:L:?1	R:R:A89	5	1	Yes	No	0	6	0	1
L:L:?1	R:R:V93	6.63	1	Yes	No	0	7	0	1
R:R:A159	R:R:S156	3.42	0	No	No	4	4	2	1
R:R:F157	R:R:F158	18.22	1	Yes	Yes	4	3	1	2
R:R:F157	R:R:F161	9.65	1	Yes	Yes	4	4	1	2
R:R:E261	R:R:F157	9.33	1	No	Yes	4	4	1	1
L:L:?1	R:R:F157	20.12	1	Yes	Yes	0	4	0	1
R:R:F158	R:R:V166	3.93	1	Yes	No	3	6	2	2
R:R:F158	R:R:L260	7.31	1	Yes	Yes	3	4	2	2
R:R:E261	R:R:F158	8.16	1	No	Yes	4	3	1	2
R:R:F165	R:R:L169	6.09	1	No	No	6	6	2	1
R:R:F241	R:R:V166	5.24	1	Yes	No	6	6	1	2
L:L:?1	R:R:L169	4.4	1	Yes	No	0	6	0	1
R:R:F241	R:R:W238	6.01	1	Yes	Yes	6	8	1	1
R:R:G268	R:R:W238	9.85	0	No	Yes	7	8	2	1
R:R:N271	R:R:W238	3.39	0	No	Yes	9	8	2	1
L:L:?1	R:R:W238	10.13	1	Yes	Yes	0	8	0	1
R:R:F241	R:R:L260	4.87	1	Yes	Yes	6	4	1	2
L:L:?1	R:R:F241	6.19	1	Yes	Yes	0	6	0	1
L:L:?1	R:R:E261	11.79	1	Yes	No	0	4	0	1
R:R:V269	R:R:W265	8.58	0	No	No	6	3	2	1
L:L:?1	R:R:W265	26.05	1	Yes	No	0	3	0	1
R:R:I58	R:R:W265	2.35	0	No	No	7	3	2	1
L:L:?1	R:R:G173	2.17	1	Yes	No	0	6	0	1
L:L:?1	R:R:S156	0.95	1	Yes	No	0	4	0	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	7WCN_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.22
Number of Linked Nodes	252
Number of Links	262
Number of Hubs	24
Number of Links mediated by Hubs	95
Number of Communities	6
Number of Nodes involved in Communities	26
Number of Links involved in Communities	30

Path Summary
Number Of Nodes in MetaPath	71
Number Of Links MetaPath	70
Number of Shortest Paths	40697
Length Of Smallest Path	3
Average Path Length	12.5384
Length of Longest Path	27
Minimum Path Strength	1.455
Average Path Strength	5.93126
Maximum Path Strength	23.085
Minimum Path Correlation	0.7
Average Path Correlation	0.94901
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	6.66667
Average % Of Corr. Nodes	67.5684
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	40.5178
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• binding • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • D1 dopamine receptor binding • protein binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • molecular function regulator activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • enzyme regulator activity • cyclase regulator activity • enzyme activator activity • cyclase activator activity • molecular function activator activity • adenylate cyclase regulator activity • adenylate cyclase activator activity • cation binding • metal ion binding • developmental process • multicellular organismal process • epithelium development • ectodermal placode morphogenesis • epidermis development • molting cycle process • hair cycle • animal organ development • hair follicle placode formation • tissue development • ectodermal placode formation • anatomical structure morphogenesis • skin development • skin epidermis development • hair follicle development
Gene Ontology	Biological Process	• developmental process • multicellular organismal process • epithelium development • ectodermal placode morphogenesis • epidermis development • molting cycle process • hair cycle • animal organ development • hair follicle placode formation • tissue development • ectodermal placode formation • anatomical structure morphogenesis • skin development • skin epidermis development • hair follicle development • molting cycle • anatomical structure development • anatomical structure formation involved in morphogenesis • ectodermal placode development • hair cycle process • cellular homeostasis • chemical homeostasis • homeostatic process • glucose homeostasis • carbohydrate homeostasis • intracellular chemical homeostasis • intracellular glucose homeostasis • system process • regulation of biological process • nervous system process • neuromuscular process • regulation of system process • biological regulation • skeletal muscle contraction • muscle contraction • muscle system process • regulation of muscle system process • striated muscle contraction • multicellular organismal movement • musculoskeletal movement • regulation of striated muscle contraction • regulation of muscle contraction • regulation of skeletal muscle contraction • regulation of multicellular organismal process • sensory perception of chemical stimulus • sensory perception • sensory perception of smell • cellular response to stimulus • cellular response to nitrogen compound • response to stimulus • response to endogenous stimulus • response to peptide hormone • cellular response to peptide hormone stimulus • response to oxygen-containing compound • response to nitrogen compound • response to glucagon • cellular response to oxygen-containing compound • cellular response to glucagon stimulus • cellular response to endogenous stimulus • cellular response to chemical stimulus • response to hormone • response to chemical • cellular process • cellular response to hormone stimulus • multicellular organism development • skeletal system development • bone development • system development • response to pH • cellular response to pH • response to abiotic stimulus • cellular response to acidic pH • response to acidic pH • cellular response to abiotic stimulus • cellular response to environmental stimulus • regulation of body fluid levels • wound healing • homotypic cell-cell adhesion • cell activation • hemostasis • platelet aggregation • blood coagulation • cell adhesion • cell-cell adhesion • response to stress • coagulation • regulation of biological quality • response to wounding • platelet activation • response to fluid shear stress • vascular endothelial cell response to laminar fluid shear stress • response to laminar fluid shear stress • cellular response to stress • cellular response to laminar fluid shear stress • vascular endothelial cell response to fluid shear stress • cellular response to fluid shear stress • cognition • developmental growth • growth • response to ketone • response to prostaglandin • response to lipid • response to alcohol • cellular response to prostaglandin stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • cellular response to lipid • response to prostaglandin E • cellular response to ketone • regulation of cellular process • signaling • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cell communication • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • signal transduction • positive regulation of biological process • adaptive thermogenesis • multicellular organismal-level homeostasis • regulation of cold-induced thermogenesis • cold-induced thermogenesis • temperature homeostasis • positive regulation of cold-induced thermogenesis • positive regulation of multicellular organismal process • positive regulation of cell communication • regulation of localization • establishment of protein localization • nitrogen compound transport • positive regulation of establishment of protein localization • localization • establishment of localization in cell • positive regulation of insulin secretion involved in cellular response to glucose stimulus • positive regulation of insulin secretion • intracellular protein localization • regulation of peptide hormone secretion • regulation of hormone levels • positive regulation of peptide hormone secretion • establishment of protein localization to extracellular region • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • cellular response to carbohydrate stimulus • response to glucose • positive regulation of protein localization • insulin secretion involved in cellular response to glucose stimulus • cellular localization • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • transport • positive regulation of secretion by cell • hormone secretion • protein localization to extracellular region • positive regulation of protein transport • peptide secretion • regulation of secretion by cell • secretion by cell • positive regulation of hormone secretion • response to monosaccharide • response to carbohydrate • positive regulation of secretion • signal release • cellular response to hexose stimulus • cellular response to monosaccharide stimulus • positive regulation of cellular process • positive regulation of peptide secretion • regulation of signaling • regulation of transport • secretion • regulation of peptide transport • regulation of establishment of protein localization • export from cell • cell-cell signaling • cellular response to glucose stimulus • regulation of protein transport • positive regulation of protein secretion • peptide transport • response to hexose • positive regulation of transport • regulation of cellular localization • protein transport • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • regulation of insulin secretion involved in cellular response to glucose stimulus • hormone transport • regulation of cell communication • insulin secretion • positive regulation of signaling • adenylate cyclase-activating adrenergic receptor signaling pathway • adrenergic receptor signaling pathway • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • cellular response to catecholamine stimulus • serotonin receptor signaling pathway • cellular response to monoamine stimulus • adenylate cyclase-activating serotonin receptor signaling pathway • intracellular transport • regulation of defense response • regulation of response to external stimulus • negative regulation of inflammatory response • negative regulation of biological process • inflammatory response to antigenic stimulus • regulation of response to stress • regulation of immune system process • negative regulation of inflammatory response to antigenic stimulus • defense response • immune response • negative regulation of response to stimulus • negative regulation of immune response • regulation of inflammatory response to antigenic stimulus • response to external stimulus • regulation of inflammatory response • regulation of response to stimulus • negative regulation of immune system process • immune system process • negative regulation of response to external stimulus • negative regulation of defense response • regulation of immune response • inflammatory response • positive regulation of adenylate cyclase activity • positive regulation of molecular function • regulation of molecular function • positive regulation of cyclase activity • activation of adenylate cyclase activity • regulation of adenylate cyclase activity • regulation of catalytic activity • positive regulation of catalytic activity • positive regulation of lyase activity • adenylate cyclase-activating dopamine receptor signaling pathway • G protein-coupled dopamine receptor signaling pathway • cell surface receptor signaling pathway • bile acid signaling pathway • adenylate cyclase-activating G protein-coupled bile acid receptor signaling pathway • renal system process • multicellular organismal-level water homeostasis • multicellular organismal-level chemical homeostasis • renal water homeostasis • cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex
Gene Ontology	Cellular Component	• cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • membrane-bounded organelle • extracellular vesicle • extracellular organelle • extracellular region • organelle • extracellular space • vesicle • extracellular membrane-bounded organelle • intracellular anatomical structure • cytoplasm • cytosol • Golgi apparatus subcompartment • Golgi apparatus • organelle subcompartment • trans-Golgi network membrane • intracellular membrane-bounded organelle • endomembrane system • intracellular organelle • trans-Golgi network • organelle membrane • protein binding • binding • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular process • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • signal transduction • cell communication • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • response to oxygen-containing compound • cellular response to oxygen-containing compound • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to chemical stimulus • cellular response to alcohol • response to hormone • response to chemical • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection • photoreceptor cell cilium • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome • synapse • cell junction • G-protein beta-subunit binding • fibroblast proliferation • cation binding • ion binding • phosphatidylcholine binding • phospholipid binding • lipid binding • quaternary ammonium group binding • small molecule binding • molecular transducer activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • establishment of protein localization • nitrogen compound transport • transport • hormone secretion • protein localization to extracellular region • localization • peptide secretion • secretion by cell • signal release • regulation of biological quality • intracellular protein localization • secretion • regulation of hormone levels • establishment of protein localization to extracellular region • export from cell • protein secretion • establishment of localization • peptide transport • protein transport • peptide hormone secretion • macromolecule localization • hormone transport • insulin secretion • receptor complex
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	8WL
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	8WL
Name	N-(2-fluoranyl-4-methylsulfonyl-phenyl)-5-nitro-6-[4-(3-propan-2-yl-1,2,4-oxadiazol-5-yl)piperidin-1-yl]pyrimidin-4-amine
Synonyms	AR231453
Identifier
Formula	C21 H24 F N7 O5 S
Molecular Weight	505.523
SMILES
PubChem	24939268
Formal Charge	0
Total Atoms	59
Total Chiral Atoms	0
Total Bonds	62
Total Aromatic Bonds	17


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q8TDV5
Sequence	>7WCN_nogp_Chain_R F S F G V I L A V L A S L I I A T N T L V A V A V L L L I H K N D G V S L C F T L N L A V A D T L I G V A I S G L L T D Q L S S P S R P T Q K T L C S L R M A F V T S S A A A S V L T V M L I T F D R Y L A I K Q P F R Y L K I M S G F V A G A C I A G L W L V S Y L I G F L P L G I P M F Q Q T A Y K G Q C S F F A V F H P H F V L T L S C V G F F P A M L L F V F F Y C D M L K I A S M H S Q Q I R K M E H A G A M A G G Y D F K A L R T V S V L I G S F A L C W T P F L I T G I V Q V A C Q E C H L Y L V L E R Y L W L L G V G N S L L N P L I Y A Y W Q K E V R L Q L Y H M A L G V K K V Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	7XZ5	A	Lipid	GPR119	GPR119	Homo sapiens	Lysophosphatidylcholine	-	Gs/β1/γ2	3.1	2022-08-24	doi.org/10.1038/s41594-022-00816-5
	7XZ5 (No Gprot)	A	Lipid	GPR119	GPR119	Homo sapiens	Lysophosphatidylcholine	-		3.1	2022-08-24	doi.org/10.1038/s41594-022-00816-5
	7XZ6	A	Lipid	GPR119	GPR119	Homo sapiens	APD668	-	Gs/β1/γ2	2.8	2022-08-24	doi.org/10.1038/s41594-022-00816-5
	7XZ6 (No Gprot)	A	Lipid	GPR119	GPR119	Homo sapiens	APD668	-		2.8	2022-08-24	doi.org/10.1038/s41594-022-00816-5
	7WCM	A	Lipid	GPR119	GPR119	Homo sapiens	MBX-2982	-	Gs/β1/γ2	2.33	2022-12-21	doi.org/10.1038/s41467-022-34696-6
	7WCM (No Gprot)	A	Lipid	GPR119	GPR119	Homo sapiens	MBX-2982	-		2.33	2022-12-21	doi.org/10.1038/s41467-022-34696-6
	7WCN	A	Lipid	GPR119	GPR119	Homo sapiens	AR231453	-	Gs/β1/γ2	2.87	2022-12-21	doi.org/10.1038/s41467-022-34696-6
	7WCN (No Gprot)	A	Lipid	GPR119	GPR119	Homo sapiens	AR231453	-		2.87	2022-12-21	doi.org/10.1038/s41467-022-34696-6
	8ZR5	A	Lipid	GPR119	GPR119	Homo sapiens	Firuglipel	-	Gs/β1/γ2	3.31	2024-06-19	To be published
	8ZR5 (No Gprot)	A	Lipid	GPR119	GPR119	Homo sapiens	Firuglipel	-		3.31	2024-06-19	To be published
	8ZRK	A	Lipid	GPR119	GPR119	Homo sapiens	GSK1292263	-	Gs/β1/γ2	2.82	2024-06-19	To be published
	8ZRK (No Gprot)	A	Lipid	GPR119	GPR119	Homo sapiens	GSK1292263	-		2.82	2024-06-19	To be published
	8VHF	A	Lipid	GPR119	GPR119	Homo sapiens	MBX-2982	-	Gs/β1/γ2	3.51	2024-10-30	doi.org/10.1016/j.str.2024.10.004
	8VHF (No Gprot)	A	Lipid	GPR119	GPR119	Homo sapiens	MBX-2982	-		3.51	2024-10-30	doi.org/10.1016/j.str.2024.10.004
	9L79	A	Lipid	GPR119	GPR119	Homo sapiens	AR231453	-	chim(NtGi1-Gs)/β1/γ2	2.98	2025-12-31	To be published
	9L79 (No Gprot)	A	Lipid	GPR119	GPR119	Homo sapiens	AR231453	-		2.98	2025-12-31	To be published
	9L80	A	Lipid	GPR119	GPR119	Homo sapiens	-	Atazanavir	chim(NtGi1-Gs)/β1/γ2	3.33	2025-12-31	To be published
	9L80 (No Gprot)	A	Lipid	GPR119	GPR119	Homo sapiens	-	Atazanavir		3.33	2025-12-31	To be published

2D representation of the interactions of this orthosteric/allosteric ligand.

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

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We apologize for the inconvenience.