Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index Hub Avg Int. Strength Num Of Links Community ConSurf
1L:L:?1 10.10581210
2R:R:F7 7.2525405
3R:R:N22 6.285429
4R:R:V25 2.115409
5R:R:F43 7.3925408
6R:R:D51 7.828529
7R:R:M82 4.0975405
8R:R:Y104 9.6025408
9R:R:W130 3.44167609
10R:R:P140 9.2775415
11R:R:F146 6.648512
12R:R:F157 7.42333614
13R:R:F158 6.895613
14R:R:F161 7.834514
15R:R:F165 9.16416
16R:R:F174 4.4775418
17R:R:F181 9.96438
18R:R:F184 6.602506
19R:R:Y185 12.16539
20R:R:I231 3.2775437
21R:R:W238 8.668518
22R:R:F241 7.278516
23R:R:E261 10.4975414
24R:R:R262 12.04413
25R:R:N275 6.2025429
26R:R:Y279 4.872549
27R:R:Y281 6.3225455
28R:R:K284 1.9375405
29R:R:Q289 6.9507
30R:R:L290 2.81405
   

Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index Node1 Node2 Recurrence Int. Strength Hub1? Hub2? Community ConSurf1 ConSurf2
1L:L:?1 R:R:F7 23.61532.71YesYes005
2R:R:F7 R:R:L11 15.29899.74YesNo056
3L:L:?1 R:R:W238 10018.35YesYes108
4R:R:S237 R:R:W238 69.79913.71NoYes178
5R:R:N271 R:R:S237 73.92777.45NoNo097
6R:R:N271 R:R:N275 74.00376.81NoYes099
7R:R:D51 R:R:N275 54.60158.08YesYes299
8R:R:D51 R:R:N22 39.8436.73YesYes299
9R:R:D51 R:R:S272 25.77688.83YesNo099
10R:R:I54 R:R:S272 23.29454.64NoNo089
11R:R:G55 R:R:I54 18.7693.53NoNo088
12R:R:G55 R:R:I19 16.48091.76NoNo086
13R:R:N22 R:R:P276 28.74879.77YesNo299
14R:R:P276 R:R:V25 27.04321.77NoYes099
15R:R:V25 R:R:V29 16.06721.6YesNo098
16R:R:L45 R:R:V29 13.82137.45NoNo068
17R:R:F174 R:R:W238 63.41616.01YesYes188
18R:R:F174 R:R:F234 66.26984.29YesNo089
19R:R:F234 R:R:V96 55.26853.93NoNo099
20R:R:V96 R:R:Y279 55.40363.79NoYes099
21R:R:I278 R:R:Y279 50.42226.04NoYes089
22R:R:I278 R:R:W282 45.1792.35NoNo087
23R:R:K284 R:R:W282 41.65821.16YesNo057
24R:R:K284 R:R:R287 36.16182.48YesNo058
25R:R:R287 R:R:Y281 32.27796.17NoYes585
26R:R:L290 R:R:Y281 28.59682.34YesYes055
27R:R:L290 R:R:V286 22.74572.98YesNo059
28R:R:L32 R:R:V286 18.76064.47NoNo079
29R:R:L32 R:R:Q289 16.742714.64NoYes077
30R:R:I33 R:R:L45 11.55864.28NoNo076
31R:R:L47 R:R:N275 66.18545.49NoYes299
32R:R:L47 R:R:T95 75.72615.9NoNo098
33R:R:N46 R:R:T95 52.79477.31NoNo098
34R:R:I126 R:R:N46 32.953412.74NoNo079
35R:R:F43 R:R:I126 29.06965.02YesNo087
36R:R:D102 R:R:F43 14.94437.17NoYes098
37R:R:D102 R:R:Y113 12.858810.34NoNo099
38R:R:N46 R:R:W130 21.0744.52NoYes099
39R:R:L129 R:R:T95 21.5894.42NoNo068
40R:R:L129 R:R:W130 19.72314.56NoYes069
41R:R:W130 R:R:Y134 20.46613.86YesNo094
42R:R:F84 R:R:Y134 12.32692.06NoNo034
43L:L:?1 R:R:F157 84.549110.15YesYes104
44R:R:F157 R:R:F161 56.957111.79YesYes144
45R:R:F161 R:R:M82 39.85144.98YesYes045
46R:R:M82 R:R:R81 32.31173.72YesNo056
47R:R:D64 R:R:R81 24.54415.96NoNo046
48R:R:D64 R:R:P69 22.93144.83NoNo045
49R:R:P69 R:R:Q154 16.87777.9NoNo052
50R:R:G153 R:R:Q154 12.75754.93NoNo032
51R:R:G153 R:R:Q74 10.67213.29NoNo037
52R:R:F161 R:R:P140 12.934811.56YesYes145
53R:R:L141 R:R:P140 16.03343.28NoYes165
54R:R:F157 R:R:F165 27.49074.29YesYes146
55R:R:F165 R:R:P140 11.254617.34YesYes165
56R:R:F181 R:R:F234 55.17565.36YesNo089
57R:R:F181 R:R:T100 27.14453.89YesNo388
58R:R:F184 R:R:T100 31.39995.19YesNo068
59R:R:F181 R:R:Y185 17.595426.82YesYes389
60R:R:F184 R:R:Y104 21.352612.38YesYes068
61R:R:K108 R:R:Y104 10.883113.14NoYes068
62R:R:F146 R:R:F165 16.430310.72YesYes126
63R:R:F157 R:R:F158 15.189111.79YesYes143
64R:R:F158 R:R:P163 23.04127.22YesNo033
65R:R:H162 R:R:P163 11.72759.15NoNo053
66R:R:F158 R:R:F241 28.28444.29YesYes136
67R:R:F174 R:R:L242 10.96763.65YesNo086
68R:R:F181 R:R:I231 10.68053.77YesYes387
69R:R:V227 R:R:Y185 24.6966.31NoYes089
70R:R:L230 R:R:Y279 16.52313.52NoYes089
71R:R:L230 R:R:Y185 15.889912.89NoYes089
72R:R:L189 R:R:V227 22.01111.49NoNo078
73R:R:L189 R:R:L224 16.59071.38NoNo077
74R:R:F221 R:R:L224 13.85513.65NoNo047
75R:R:F241 R:R:L264 12.52963.65YesNo164
76R:R:L264 R:R:P240 12.41984.93NoNo049
77R:R:F241 R:R:W238 32.054.01YesYes168
78R:R:N275 R:R:V96 52.13614.43YesNo099
79R:R:D51 R:R:L47 11.13648.14YesNo299
Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Links and nodes colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
L:L:?1 R:R:A89 3.5 1 Yes No 0 6 0 1
L:L:?1 R:R:A90 3.5 1 Yes No 0 7 0 1
L:L:?1 R:R:V93 4.97 1 Yes No 0 7 0 1
L:L:?1 R:R:L94 4.61 1 Yes No 0 5 0 1
L:L:?1 R:R:F157 10.15 1 Yes Yes 0 4 0 1
L:L:?1 R:R:L169 9.23 1 Yes No 0 6 0 1
L:L:?1 R:R:W238 18.35 1 Yes Yes 0 8 0 1
L:L:?1 R:R:F241 8.12 1 Yes Yes 0 6 0 1
L:L:?1 R:R:R262 32.4 1 Yes Yes 0 3 0 1
L:L:?1 R:R:W265 22.78 1 Yes No 0 3 0 1
R:R:F7 R:R:L11 9.74 0 Yes No 5 6 1 2
R:R:F7 R:R:Q65 14.05 0 Yes No 5 4 1 2
R:R:F157 R:R:F158 11.79 1 Yes Yes 4 3 1 2
R:R:F157 R:R:F161 11.79 1 Yes Yes 4 4 1 2
R:R:F157 R:R:F165 4.29 1 Yes Yes 4 6 1 2
R:R:F157 R:R:V166 3.93 1 Yes No 4 6 1 2
R:R:F158 R:R:V166 3.93 1 Yes No 3 6 2 2
R:R:F158 R:R:F241 4.29 1 Yes Yes 3 6 2 1
R:R:E261 R:R:F158 10.49 1 Yes Yes 4 3 2 2
R:R:F161 R:R:F165 4.29 1 Yes Yes 4 6 2 2
R:R:F174 R:R:S237 3.96 1 Yes No 8 7 2 2
R:R:F174 R:R:W238 6.01 1 Yes Yes 8 8 2 1
R:R:S237 R:R:W238 3.71 1 No Yes 7 8 2 1
R:R:F241 R:R:W238 4.01 1 Yes Yes 6 8 1 1
R:R:G268 R:R:W238 11.26 0 No Yes 7 8 2 1
R:R:E261 R:R:F241 16.32 1 Yes Yes 4 6 2 1
R:R:F241 R:R:L264 3.65 1 Yes No 6 4 1 2
R:R:E261 R:R:L264 5.3 1 Yes No 4 4 2 2
R:R:R262 R:R:Y263 4.12 1 Yes No 3 4 1 2
R:R:R262 R:R:W265 9 1 Yes No 3 3 1 1
R:R:L266 R:R:W265 6.83 0 No No 5 3 2 1
L:L:?1 R:R:F7 2.71 1 Yes Yes 0 5 0 1
R:R:R262 R:R:S156 2.64 1 Yes No 3 4 1 2
R:R:F157 R:R:T86 2.59 1 Yes No 4 5 1 2
R:R:F7 R:R:I10 2.51 0 Yes No 5 4 1 2
L:L:?1 R:R:G173 0.95 1 Yes No 0 6 0 1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB 8ZR5_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.
Net Summary
Imin 3.28
Number of Linked Nodes 248
Number of Links 264
Number of Hubs 30
Number of Links mediated by Hubs 118
Number of Communities 5
Number of Nodes involved in Communities 37
Number of Links involved in Communities 50
Path Summary
Number Of Nodes in MetaPath 80
Number Of Links MetaPath 79
Number of Shortest Paths 33736
Length Of Smallest Path 3
Average Path Length 11.9036
Length of Longest Path 29
Minimum Path Strength 1.19
Average Path Strength 6.48941
Maximum Path Strength 28.565
Minimum Path Correlation 0.7
Average Path Correlation 0.945236
Maximum Path Correlation 1
Minimum % Of Corr. Nodes 7.14286
Average % Of Corr. Nodes 66.4208
Maximum % Of Corr. Nodes 100
Minimum Path Hubs % 0
Average Path Hubs % 42.1781
Maximum Path Hubs % 100
AnnotationTypeLinks
Gene OntologyMolecular Function• binding   • guanyl nucleotide binding   • GTP binding   • nucleotide binding   • guanyl ribonucleotide binding   • purine ribonucleotide binding   • purine ribonucleoside triphosphate binding   • nucleoside phosphate binding   • ion binding   • purine nucleotide binding   • anion binding   • heterocyclic compound binding   • carbohydrate derivative binding   • ribonucleotide binding   • small molecule binding   • D1 dopamine receptor binding   • protein binding   • signaling receptor binding   • G protein-coupled receptor binding   • dopamine receptor binding   • protein-containing complex binding   • G-protein beta/gamma-subunit complex binding   • pyrophosphatase activity   • GTPase activity   • G protein activity   • ribonucleoside triphosphate phosphatase activity   • molecular function regulator activity   • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides   • hydrolase activity   • hydrolase activity, acting on acid anhydrides   • catalytic activity   • enzyme regulator activity   • molecular function activator activity   • phosphorus-oxygen lyase activity   • cyclase regulator activity   • enzyme activator activity   • cyclase activator activity   • cyclase activity   • adenylate cyclase regulator activity   • lyase activity   • adenylate cyclase activator activity   • adenylate cyclase activity   • cation binding   • metal ion binding   • developmental process   • multicellular organismal process   • epithelium development   • ectodermal placode morphogenesis   • epidermis development   • molting cycle process   • hair cycle   • animal organ development   • hair follicle placode formation   • tissue development   • ectodermal placode formation   • anatomical structure morphogenesis   • skin development   • skin epidermis development   • hair follicle development
Gene OntologyBiological Process• developmental process   • multicellular organismal process   • epithelium development   • ectodermal placode morphogenesis   • epidermis development   • molting cycle process   • hair cycle   • animal organ development   • hair follicle placode formation   • tissue development   • ectodermal placode formation   • anatomical structure morphogenesis   • skin development   • skin epidermis development   • hair follicle development   • molting cycle   • anatomical structure development   • anatomical structure formation involved in morphogenesis   • ectodermal placode development   • hair cycle process   • system process   • sensory perception of chemical stimulus   • sensory perception   • nervous system process   • sensory perception of smell   • cellular response to stimulus   • cellular response to nitrogen compound   • response to stimulus   • response to endogenous stimulus   • response to peptide hormone   • cellular response to peptide hormone stimulus   • response to oxygen-containing compound   • response to nitrogen compound   • response to glucagon   • cellular response to oxygen-containing compound   • cellular response to glucagon stimulus   • cellular response to endogenous stimulus   • cellular response to chemical stimulus   • response to hormone   • response to chemical   • cellular process   • cellular response to hormone stimulus   • multicellular organism development   • skeletal system development   • bone development   • system development   • regulation of body fluid levels   • wound healing   • homotypic cell-cell adhesion   • cell activation   • hemostasis   • biological regulation   • platelet aggregation   • blood coagulation   • cell adhesion   • cell-cell adhesion   • response to stress   • coagulation   • regulation of biological quality   • response to wounding   • platelet activation   • response to fluid shear stress   • vascular endothelial cell response to laminar fluid shear stress   • response to laminar fluid shear stress   • cellular response to stress   • cellular response to laminar fluid shear stress   • vascular endothelial cell response to fluid shear stress   • cellular response to fluid shear stress   • cognition   • developmental growth   • growth   • response to ketone   • response to prostaglandin   • response to lipid   • response to alcohol   • cellular response to prostaglandin stimulus   • cellular response to prostaglandin E stimulus   • cellular response to alcohol   • cellular response to lipid   • response to prostaglandin E   • cellular response to ketone   • regulation of biological process   • regulation of cellular process   • signaling   • adenylate cyclase-activating G protein-coupled receptor signaling pathway   • cell communication   • adenylate cyclase-modulating G protein-coupled receptor signaling pathway   • G protein-coupled receptor signaling pathway   • signal transduction   • homeostatic process   • positive regulation of biological process   • adaptive thermogenesis   • positive regulation of metabolic process   • multicellular organismal-level homeostasis   • regulation of cold-induced thermogenesis   • cold-induced thermogenesis   • temperature homeostasis   • positive regulation of cold-induced thermogenesis   • positive regulation of multicellular organismal process   • metabolic process   • regulation of multicellular organismal process   • regulation of metabolic process   • positive regulation of cellular process   • protein localization   • regulation of localization   • establishment of protein localization   • nitrogen compound transport   • localization   • cellular macromolecule localization   • regulation of peptide hormone secretion   • regulation of hormone levels   • establishment of protein localization to extracellular region   • protein secretion   • establishment of localization   • regulation of protein secretion   • regulation of secretion   • cellular localization   • regulation of hormone secretion   • regulation of protein localization   • regulation of peptide secretion   • transport   • hormone secretion   • protein localization to extracellular region   • peptide secretion   • regulation of secretion by cell   • secretion by cell   • amide transport   • signal release   • regulation of signaling   • regulation of transport   • secretion   • regulation of peptide transport   • regulation of establishment of protein localization   • export from cell   • cell-cell signaling   • regulation of protein transport   • peptide transport   • protein transport   • regulation of cellular localization   • regulation of insulin secretion   • peptide hormone secretion   • macromolecule localization   • hormone transport   • regulation of cell communication   • insulin secretion   • adenylate cyclase-activating adrenergic receptor signaling pathway   • adrenergic receptor signaling pathway   • establishment of localization in cell   • intracellular transport   • regulation of defense response   • regulation of response to external stimulus   • negative regulation of inflammatory response   • negative regulation of biological process   • inflammatory response to antigenic stimulus   • regulation of response to stress   • regulation of immune system process   • negative regulation of inflammatory response to antigenic stimulus   • defense response   • immune response   • negative regulation of response to stimulus   • negative regulation of immune response   • regulation of inflammatory response to antigenic stimulus   • response to external stimulus   • regulation of inflammatory response   • regulation of response to stimulus   • negative regulation of immune system process   • immune system process   • negative regulation of response to external stimulus   • negative regulation of defense response   • regulation of immune response   • inflammatory response   • positive regulation of adenylate cyclase activity   • positive regulation of molecular function   • regulation of molecular function   • positive regulation of cyclase activity   • activation of adenylate cyclase activity   • regulation of adenylate cyclase activity   • regulation of catalytic activity   • positive regulation of catalytic activity   • positive regulation of lyase activity   • response to dopamine   • cellular response to dopamine   • response to monoamine   • response to catecholamine   • adenylate cyclase-activating dopamine receptor signaling pathway   • cellular response to catecholamine stimulus   • G protein-coupled dopamine receptor signaling pathway   • cellular response to monoamine stimulus   • renal system process   • chemical homeostasis   • multicellular organismal-level water homeostasis   • multicellular organismal-level chemical homeostasis   • renal water homeostasis   • cellular anatomical structure   • membrane   • protein-containing complex   • extrinsic component of plasma membrane   • catalytic complex   • plasma membrane protein complex   • cytoplasmic side of membrane   • plasma membrane   • membrane protein complex   • heterotrimeric G-protein complex   • side of membrane   • cell periphery   • cytoplasmic side of plasma membrane   • GTPase complex
Gene OntologyCellular Component• cellular anatomical structure   • membrane   • protein-containing complex   • extrinsic component of plasma membrane   • catalytic complex   • plasma membrane protein complex   • cytoplasmic side of membrane   • plasma membrane   • membrane protein complex   • heterotrimeric G-protein complex   • side of membrane   • cell periphery   • cytoplasmic side of plasma membrane   • GTPase complex   • extrinsic component of membrane   • extrinsic component of cytoplasmic side of plasma membrane   • extracellular exosome   • membrane-bounded organelle   • extracellular vesicle   • extracellular organelle   • extracellular region   • organelle   • extracellular space   • vesicle   • extracellular membrane-bounded organelle   • intracellular anatomical structure   • cytoplasm   • cytosol   • Golgi apparatus subcompartment   • Golgi apparatus   • organelle subcompartment   • trans-Golgi network membrane   • intracellular membrane-bounded organelle   • endomembrane system   • intracellular organelle   • trans-Golgi network   • organelle membrane   • protein binding   • binding   • enzyme binding   • GTPase binding   • protein-containing complex binding   • pyrophosphatase activity   • GTPase activity   • ribonucleoside triphosphate phosphatase activity   • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides   • hydrolase activity   • hydrolase activity, acting on acid anhydrides   • catalytic activity   • signaling receptor complex adaptor activity   • protein-macromolecule adaptor activity   • molecular adaptor activity   • signaling adaptor activity   • multicellular organismal process   • system process   • sensory perception of chemical stimulus   • sensory perception   • nervous system process   • sensory perception of taste   • developmental process   • sensory organ development   • eye development   • animal organ development   • retina development in camera-type eye   • visual system development   • multicellular organism development   • camera-type eye development   • anatomical structure development   • sensory system development   • system development   • cell population proliferation   • cellular process   • cellular response to stimulus   • regulation of biological process   • regulation of cellular process   • response to stimulus   • signaling   • biological regulation   • signal transduction   • cell communication   • response to ketone   • response to prostaglandin   • response to lipid   • response to endogenous stimulus   • response to alcohol   • cellular response to prostaglandin stimulus   • response to oxygen-containing compound   • cellular response to oxygen-containing compound   • cellular response to endogenous stimulus   • cellular response to prostaglandin E stimulus   • cellular response to chemical stimulus   • cellular response to alcohol   • response to hormone   • response to chemical   • cellular response to lipid   • response to prostaglandin E   • cellular response to ketone   • cellular response to hormone stimulus   • small GTPase-mediated signal transduction   • Ras protein signal transduction   • intracellular signal transduction   • intracellular signaling cassette   • phospholipase C-activating G protein-coupled receptor signaling pathway   • G protein-coupled receptor signaling pathway   • cellular response to nitrogen compound   • response to dopamine   • cellular response to dopamine   • response to monoamine   • response to catecholamine   • adenylate cyclase-activating dopamine receptor signaling pathway   • cellular response to catecholamine stimulus   • G protein-coupled dopamine receptor signaling pathway   • response to nitrogen compound   • adenylate cyclase-activating G protein-coupled receptor signaling pathway   • cellular response to monoamine stimulus   • adenylate cyclase-modulating G protein-coupled receptor signaling pathway   • synaptic signaling   • cellular response to acetylcholine   • cell-cell signaling   • acetylcholine receptor signaling pathway   • postsynaptic signal transduction   • G protein-coupled acetylcholine receptor signaling pathway   • response to acetylcholine   • non-motile cilium   • 9+0 non-motile cilium   • cilium   • neuron projection   • photoreceptor disc membrane   • photoreceptor outer segment   • plasma membrane bounded cell projection   • cell projection   • photoreceptor cell cilium   • vacuolar membrane   • lytic vacuole   • vacuole   • lytic vacuole membrane   • bounding membrane of organelle   • lysosomal membrane   • lysosome   • synapse   • cell junction   • G-protein beta-subunit binding   • fibroblast proliferation   • cation binding   • ion binding   • phosphatidylcholine binding   • phospholipid binding   • lipid binding   • quaternary ammonium group binding   • small molecule binding   • molecular transducer activity   • G protein-coupled receptor activity   • transmembrane signaling receptor activity   • signaling receptor activity   • metabolic process   • regulation of metabolic process   • protein localization   • establishment of protein localization   • cellular localization   • nitrogen compound transport   • transport   • hormone secretion   • protein localization to extracellular region   • peptide secretion   • localization   • secretion by cell   • amide transport   • signal release   • cellular macromolecule localization   • regulation of biological quality   • secretion   • regulation of hormone levels   • establishment of protein localization to extracellular region   • export from cell   • protein secretion   • establishment of localization   • peptide transport   • protein transport   • peptide hormone secretion   • macromolecule localization   • hormone transport   • insulin secretion   • receptor complex
SCOP2Domain Identifier• Transducin (heterotrimeric G protein), gamma chain
SCOP2Family Identifier• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations-• Orientations of Proteins in Membranes database (OPM)   • Protein Data Bank of Transmembrane Proteins (PDBTM)   • MemProtMD


Details about the values in these tables can be found in the corresponding documentation page .
CodeA1D
PDB ResiduesL:L:?1
Environment DetailsOpen EMBL-EBI Page
CodeA1D
Name
Synonyms
Identifier
Formula
Molecular Weight
SMILES
PubChem
Formal Charge
Total Atoms
Total Chiral Atoms
Total Bonds
Total Aromatic Bonds

PDBsumOpen PDBsum Page
ChainR
ProteinReceptor
UniProtQ8TDV5
Sequence
>8ZR5_nogp_Chain_R
SFGVILAVL ASLIIATNT LVAVAVLLL IHKNDGVSL CFTLNLAVA 
DTLIGVAIS GLLTDQLSS PSRPTQKTL CSLRMAFVT SSAAASVLT 
VMLITFDRY LAIKQPFRY LKIMSGFVA GACIAGLWL VSYLIGFLP 
LGIPMFQQT AYKGQCSFF AVFHPHFVL TLSCVGFFP AMLLFVFFY 
CDMLKIASM HSQQIRKME HAGAMAGDF KALRTVSVL IGSFALSWT 
PFLITGIVQ VACQECHLY LVLERYLWL LGVGNSLLN PLIYAYWQK 
EVRLQLYHM ALGVK


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  




This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
8VHFALipidGPR119GPR119Homo sapiensMBX-2982-Gs/β1/γ23.512024-10-30doi.org/10.1016/j.str.2024.10.004
8VHF (No Gprot) ALipidGPR119GPR119Homo sapiensMBX-2982-3.512024-10-30doi.org/10.1016/j.str.2024.10.004
8ZRKALipidGPR119GPR119Homo sapiensGSK-1292263-Gs/β1/γ22.822024-06-19To be published
8ZRK (No Gprot) ALipidGPR119GPR119Homo sapiensGSK-1292263-2.822024-06-19To be published
8ZR5ALipidGPR119GPR119Homo sapiensFiruglipel-Gs/β1/γ23.312024-06-19To be published
8ZR5 (No Gprot) ALipidGPR119GPR119Homo sapiensFiruglipel-3.312024-06-19To be published
7WCNALipidGPR119GPR119Homo sapiensAR231453-Gs/β1/γ22.872022-12-2110.1038/s41467-022-34696-6
7WCN (No Gprot) ALipidGPR119GPR119Homo sapiensAR231453-2.872022-12-2110.1038/s41467-022-34696-6
7WCMALipidGPR119GPR119Homo sapiensMBX-2982-Gs/β1/γ22.332022-12-2110.1038/s41467-022-34696-6
7WCM (No Gprot) ALipidGPR119GPR119Homo sapiensMBX-2982-2.332022-12-2110.1038/s41467-022-34696-6
7XZ6ALipidGPR119GPR119Homo sapiensAPD668-Gs/β1/γ22.82022-08-2410.1038/s41594-022-00816-5
7XZ6 (No Gprot) ALipidGPR119GPR119Homo sapiensAPD668-2.82022-08-2410.1038/s41594-022-00816-5
7XZ5ALipidGPR119GPR119Homo sapiensLysophosphatidylcholine-Gs/β1/γ23.12022-08-2410.1038/s41594-022-00816-5
7XZ5 (No Gprot) ALipidGPR119GPR119Homo sapiensLysophosphatidylcholine-3.12022-08-2410.1038/s41594-022-00816-5




You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 8ZR5_nogp.zip



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