psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:L303	R:R:T28	7.37	No	No	0	4	5
2	R:R:I29	R:R:I83	4.42	Yes	No	0	5	6
3	R:R:I29	R:R:S86	4.64	Yes	No	0	5	4
4	R:R:I29	R:R:I87	7.36	Yes	No	0	5	5
5	R:R:I83	R:R:V32	4.61	No	No	0	6	7
6	R:R:V32	R:R:Y310	6.31	No	Yes	0	7	7
7	R:R:I35	R:R:L311	8.56	No	No	0	7	5
8	R:R:C36	R:R:Y310	4.03	No	Yes	0	6	7
9	R:R:I40	R:R:L72	4.28	Yes	No	0	6	7
10	R:R:D71	R:R:N43	12.12	No	No	4	9	9
11	R:R:L72	R:R:N43	15.1	No	No	0	7	9
12	R:R:N43	R:R:P317	8.15	No	No	4	9	9
13	R:R:F331	R:R:M45	4.98	No	No	0	7	7
14	R:R:N321	R:R:V46	8.87	No	No	5	7	9
15	R:R:F327	R:R:V46	5.24	Yes	No	5	8	9
16	R:R:M51	R:R:V47	4.56	No	No	0	4	7
17	R:R:F327	R:R:V49	9.18	Yes	No	0	8	8
18	R:R:M56	R:R:V50	6.09	Yes	No	0	8	8
19	R:R:V50	R:R:V65	4.81	No	No	0	8	6
20	R:R:M51	R:R:R52	3.72	No	No	0	4	5
21	R:R:M56	R:R:T53	6.02	Yes	No	0	8	6
22	R:R:K333	R:R:T53	9.01	No	No	0	4	6
23	R:R:H55	R:R:K326	3.93	No	No	0	5	6
24	R:R:M56	R:R:N61	15.43	Yes	No	6	8	9
25	R:R:K326	R:R:M56	4.32	No	Yes	6	6	8
26	R:R:F139	R:R:R57	10.69	No	No	0	3	8
27	R:R:P59	R:R:T58	5.25	No	No	0	6	7
28	R:R:N61	R:R:T58	10.24	No	No	0	9	7
29	R:R:E122	R:R:P59	4.72	No	No	0	8	6
30	R:R:F119	R:R:T60	6.49	Yes	No	0	9	9
31	R:R:K326	R:R:N61	6.99	No	No	6	6	9
32	R:R:C62	R:R:F139	4.19	No	No	0	4	3
33	R:R:C62	R:R:I146	4.91	No	No	0	4	7
34	R:R:F119	R:R:Y63	6.19	Yes	Yes	0	9	8
35	R:R:E122	R:R:Y63	13.47	No	Yes	0	8	8
36	R:R:A142	R:R:Y63	5.34	No	Yes	0	7	8
37	R:R:I145	R:R:Y63	10.88	No	Yes	0	6	8
38	R:R:F119	R:R:L64	7.31	Yes	No	0	9	8
39	R:R:L64	R:R:N321	9.61	No	No	0	8	7
40	R:R:S115	R:R:S66	4.89	No	No	0	8	9
41	R:R:I146	R:R:S66	6.19	No	No	0	7	9
42	R:R:S66	R:R:W150	6.18	No	Yes	0	9	9
43	R:R:L67	R:R:S115	6.01	Yes	No	0	9	8
44	R:R:I116	R:R:L67	7.14	No	Yes	0	8	9
45	R:R:L67	R:R:N316	5.49	Yes	No	0	9	9
46	R:R:V69	R:R:W150	3.68	No	Yes	0	7	9
47	R:R:D71	R:R:P317	4.83	No	No	4	9	9
48	R:R:L107	R:R:M73	4.24	No	No	0	5	6
49	R:R:G108	R:R:V74	3.68	No	No	0	7	7
50	R:R:I109	R:R:V74	9.22	Yes	No	0	7	7
51	R:R:L75	R:R:S313	7.51	No	No	0	7	9
52	R:R:A78	R:R:Q105	6.06	No	No	1	7	7
53	R:R:A78	R:R:Y310	4	No	Yes	1	7	7
54	L:L:?3	R:R:A78	4.34	Yes	No	1	0	7
55	R:R:G79	R:R:Y310	4.35	No	Yes	0	7	7
56	R:R:P81	R:R:Y93	4.17	No	Yes	3	5	6
57	R:R:I101	R:R:P81	5.08	No	No	3	5	5
58	R:R:N82	R:R:S86	4.47	No	No	0	6	4
59	R:R:N82	R:R:R306	8.44	No	No	1	6	5
60	R:R:N82	R:R:Y310	5.81	No	Yes	1	6	7
61	R:R:T84	R:R:Y88	3.75	No	No	0	4	5
62	R:R:T84	R:R:Y93	9.99	No	Yes	0	4	6
63	R:R:D85	R:R:W91	8.93	No	Yes	0	4	8
64	R:R:I87	R:R:Y88	6.04	No	No	0	5	5
65	R:R:W91	R:R:Y93	4.82	Yes	Yes	3	8	6
66	R:R:C98	R:R:W91	3.92	No	Yes	0	9	8
67	R:R:I101	R:R:W91	5.87	No	Yes	3	5	8
68	R:R:C179	R:R:W91	15.67	No	Yes	0	9	8
69	R:R:I101	R:R:Y93	4.84	No	Yes	3	5	6
70	R:R:L99	R:R:Y95	11.72	No	No	0	5	3
71	R:R:D165	R:R:Y95	12.64	No	No	0	5	3
72	R:R:C98	R:R:L166	7.94	No	No	0	9	4
73	R:R:L164	R:R:L99	4.15	No	No	0	5	5
74	R:R:T102	R:R:Y106	4.99	No	Yes	1	4	5
75	R:R:L164	R:R:T102	7.37	No	No	0	5	4
76	L:L:H2	R:R:T102	9.58	Yes	No	1	0	4
77	R:R:C157	R:R:Y103	9.41	No	Yes	0	7	6
78	R:R:M158	R:R:Y103	9.58	No	Yes	0	4	6
79	R:R:F161	R:R:Y103	17.54	No	Yes	0	5	6
80	L:L:?3	R:R:Q105	13.45	Yes	No	1	0	7
81	R:R:W160	R:R:Y106	36.66	Yes	Yes	1	5	5
82	R:R:Y106	R:R:Y181	3.97	Yes	Yes	1	5	4
83	R:R:Y106	R:R:Y192	3.97	Yes	Yes	1	5	5
84	L:L:H2	R:R:Y106	7.62	Yes	Yes	1	0	5
85	L:L:?3	R:R:Y106	6.46	Yes	Yes	1	0	5
86	R:R:L107	R:R:S154	4.5	No	No	0	5	4
87	R:R:I109	R:R:W279	4.7	Yes	Yes	1	7	8
88	R:R:I109	R:R:R283	3.76	Yes	Yes	1	7	6
89	L:L:?3	R:R:I109	3.93	Yes	Yes	1	0	7
90	R:R:N110	R:R:T153	4.39	No	No	0	6	8
91	R:R:N110	R:R:Y156	5.81	No	No	2	6	5
92	R:R:F199	R:R:N110	6.04	Yes	No	2	5	6
93	R:R:A111	R:R:W150	3.89	No	Yes	0	7	9
94	R:R:F199	R:R:S113	3.96	Yes	No	0	5	7
95	R:R:F275	R:R:I116	6.28	No	No	0	9	8
96	R:R:I116	R:R:Y320	7.25	No	No	0	8	9
97	R:R:F119	R:R:R123	14.97	Yes	No	0	9	9
98	R:R:T120	R:R:Y211	7.49	No	Yes	0	8	9
99	R:R:C137	R:R:E122	9.12	No	No	0	7	8
100	R:R:R123	R:R:Y211	9.26	No	Yes	0	9	9
101	R:R:R123	R:R:Y320	6.17	No	No	0	9	9
102	R:R:C128	R:R:Y124	6.72	No	Yes	7	7	8
103	R:R:H129	R:R:Y124	10.89	Yes	Yes	7	6	8
104	R:R:L210	R:R:Y124	11.72	No	Yes	0	7	8
105	R:R:I127	R:R:I214	14.72	No	No	0	9	9
106	R:R:C128	R:R:H129	4.42	No	Yes	7	7	6
107	R:R:C128	R:R:I217	4.91	No	No	0	7	6
108	R:R:F135	R:R:I131	3.77	No	No	0	4	7
109	R:R:F135	R:R:Q134	4.68	No	No	0	4	6
110	R:R:L136	R:R:R141	15.79	No	Yes	0	4	5
111	R:R:S140	R:R:T138	4.8	No	No	0	4	8
112	R:R:F139	R:R:K143	14.89	No	No	0	3	4
113	R:R:K144	R:R:R141	3.71	No	Yes	0	3	5
114	R:R:I145	R:R:R141	7.52	No	Yes	0	6	5
115	R:R:I146	R:R:I147	4.42	No	No	0	7	3
116	R:R:M194	R:R:Y156	8.38	No	No	2	5	5
117	R:R:F199	R:R:Y156	14.44	Yes	No	2	5	5
118	R:R:C157	R:R:W160	5.22	No	Yes	0	7	5
119	R:R:W160	R:R:Y192	7.72	Yes	Yes	1	5	5
120	R:R:L163	R:R:Y188	5.86	No	No	0	4	5
121	R:R:I177	R:R:L166	5.71	No	No	0	4	4
122	R:R:I177	R:R:N167	5.66	No	No	0	4	1
123	L:L:H2	R:R:C179	7.37	Yes	No	0	0	9
124	R:R:R185	R:R:Y181	7.2	Yes	Yes	1	2	4
125	R:R:Y181	R:R:Y188	16.88	Yes	No	0	4	5
126	R:R:Y181	R:R:Y192	10.92	Yes	Yes	1	4	5
127	L:L:?1	R:R:Y181	5.02	Yes	Yes	1	0	4
128	L:L:H2	R:R:Y181	5.44	Yes	Yes	1	0	4
129	R:R:I183	R:R:K182	5.82	No	No	0	2	4
130	R:R:I183	R:R:Y187	7.25	No	No	0	2	1
131	R:R:I183	R:R:Y188	4.84	No	No	0	2	5
132	R:R:S184	R:R:Y187	3.82	No	No	0	4	1
133	R:R:R185	R:R:Y192	7.2	Yes	Yes	1	2	5
134	L:L:?1	R:R:R185	11.7	Yes	Yes	1	0	2
135	R:R:P190	R:R:S189	5.34	No	No	0	4	3
136	R:R:V286	R:R:Y192	11.36	No	Yes	1	6	5
137	L:L:?1	R:R:Y192	3.76	Yes	Yes	1	0	5
138	R:R:M194	R:R:V198	4.56	No	No	2	5	5
139	R:R:F199	R:R:M194	3.73	Yes	No	2	5	5
140	R:R:D195	R:R:R283	14.29	No	Yes	0	6	6
141	R:R:F196	R:R:Y200	10.32	No	Yes	0	6	8
142	R:R:F196	R:R:V201	3.93	No	No	0	6	5
143	R:R:F196	R:R:V287	5.24	No	No	0	6	6
144	R:R:F199	R:R:V198	5.24	Yes	No	2	5	5
145	R:R:V198	R:R:V202	4.81	No	No	0	5	5
146	R:R:M280	R:R:Y200	8.38	No	Yes	0	6	8
147	R:R:R283	R:R:Y200	14.4	Yes	Yes	0	6	8
148	R:R:F213	R:R:V209	7.87	No	No	0	5	5
149	R:R:L268	R:R:Y211	12.89	No	Yes	0	8	9
150	R:R:V272	R:R:Y211	5.05	No	Yes	0	8	9
151	R:R:F213	R:R:R216	7.48	No	No	0	5	4
152	R:R:L218	R:R:R261	4.86	No	Yes	0	8	7
153	R:R:F219	R:R:T265	9.08	No	No	0	5	8
154	R:R:K262	R:R:R261	13.61	No	Yes	0	5	7
155	R:R:K266	R:R:M267	7.2	No	No	0	7	9
156	R:R:K266	R:R:V270	6.07	No	No	0	7	7
157	R:R:I319	R:R:V271	7.68	No	No	0	8	8
158	R:R:V271	R:R:Y320	6.31	No	No	0	8	9
159	R:R:F275	R:R:W279	20.04	No	Yes	0	9	8
160	R:R:L278	R:R:N312	10.98	No	No	0	8	9
161	R:R:R283	R:R:W279	8	Yes	Yes	1	6	8
162	R:R:N312	R:R:W279	15.82	No	Yes	0	9	8
163	R:R:M280	R:R:T284	6.02	No	No	0	6	6
164	R:R:V286	R:R:Y282	8.83	No	Yes	1	6	5
165	R:R:C305	R:R:Y282	4.03	No	Yes	0	5	5
166	R:R:I309	R:R:Y282	7.25	No	Yes	1	6	5
167	L:L:?1	R:R:Y282	6.27	Yes	Yes	1	0	5
168	L:L:?3	R:R:Y282	15.08	Yes	Yes	1	0	5
169	R:R:L285	R:R:N289	9.61	No	Yes	0	4	4
170	L:L:?1	R:R:V286	7.97	Yes	No	1	0	6
171	R:R:F296	R:R:N289	4.83	No	Yes	0	1	4
172	L:L:?1	R:R:N289	10.28	Yes	Yes	0	0	4
173	R:R:F291	R:R:S290	3.96	No	No	0	5	4
174	R:R:E298	R:R:F296	10.49	No	No	0	3	1
175	R:R:F296	R:R:F301	7.5	No	No	0	1	4
176	R:R:E298	R:R:W300	4.36	No	No	0	3	2
177	R:R:F301	R:R:W300	4.01	No	No	0	4	2
178	L:L:?1	R:R:L302	5.92	Yes	No	0	0	4
179	R:R:I307	R:R:L303	7.14	No	No	0	5	4
180	R:R:C308	R:R:F304	8.38	No	No	0	7	4
181	R:R:R306	R:R:Y310	7.2	No	Yes	1	5	7
182	L:L:?3	R:R:R306	12.28	Yes	No	1	0	5
183	L:L:?3	R:R:I309	7.87	Yes	No	1	0	6
184	R:R:N312	R:R:N316	8.17	No	No	0	9	9
185	R:R:L322	R:R:V318	4.47	No	No	0	5	7
186	R:R:F327	R:R:N321	8.46	Yes	No	5	8	7
187	R:R:F327	R:R:L322	7.31	Yes	No	0	8	5
188	R:R:K333	R:R:L334	4.23	No	No	0	4	6
189	L:L:?1	L:L:H2	4.13	Yes	Yes	1	0	0
190	L:L:?3	L:L:H2	4.73	Yes	Yes	1	0	0
191	R:R:N221	R:R:R261	3.62	No	Yes	0	7	7
192	R:R:M204	R:R:Y200	3.59	No	Yes	0	6	8
193	R:R:D195	R:R:F199	3.58	No	Yes	0	6	5
194	R:R:P295	R:R:S294	3.56	No	No	0	1	2
195	R:R:P203	R:R:V202	3.53	No	No	0	9	5
196	R:R:L75	R:R:Y310	3.52	No	Yes	0	7	7
197	R:R:L107	R:R:Y103	3.52	No	Yes	0	5	6
198	R:R:I191	R:R:W160	3.52	No	Yes	0	7	5
199	R:R:P203	R:R:T117	3.5	No	No	0	9	7
200	R:R:C114	R:R:T153	3.38	No	No	0	5	8
201	R:R:A207	R:R:T120	3.36	No	No	0	8	8
202	R:R:A215	R:R:T265	3.36	No	No	0	7	8
203	R:R:M280	R:R:P281	3.35	No	No	0	6	9
204	R:R:C137	R:R:I125	3.27	No	No	0	7	4
205	R:R:S189	R:R:S290	3.26	No	No	0	3	4
206	R:R:S290	R:R:V287	3.23	No	No	0	4	6
207	R:R:C100	R:R:L104	3.17	No	No	0	4	4
208	R:R:T208	R:R:V272	3.17	No	No	0	5	8
209	R:R:C308	R:R:L278	3.17	No	No	0	7	8
210	R:R:P295	R:R:Q297	3.16	No	No	0	1	3
211	R:R:F213	R:R:Y124	3.09	No	Yes	0	5	8
212	R:R:I29	R:R:V26	3.07	Yes	No	0	5	5
213	R:R:I40	R:R:V76	3.07	Yes	No	0	6	4
214	R:R:L67	R:R:S112	3	Yes	No	0	9	9
215	R:R:L31	R:R:V27	2.98	No	No	0	4	5
216	R:R:L80	R:R:V76	2.98	No	No	0	8	4
217	R:R:L206	R:R:V202	2.98	No	No	0	6	5
218	R:R:L218	R:R:V264	2.98	No	No	0	8	8
219	R:R:L268	R:R:V264	2.98	No	No	0	8	8
220	R:R:L274	R:R:V270	2.98	No	No	0	6	7
221	R:R:N289	R:R:V288	2.96	Yes	No	0	4	4
222	R:R:L210	R:R:T120	2.95	No	No	0	7	8
223	R:R:I40	R:R:I44	2.94	Yes	No	0	6	5
224	R:R:D71	R:R:S313	2.94	No	No	0	9	9
225	R:R:I121	R:R:I125	2.94	No	No	0	6	4
226	R:R:M267	R:R:M323	2.89	No	No	0	9	8
227	R:R:P295	R:R:R185	2.88	No	Yes	0	1	2
228	R:R:I34	R:R:L38	2.85	No	No	0	4	5
229	R:R:I44	R:R:L48	2.85	No	No	0	5	5
230	R:R:I214	R:R:L218	2.85	No	No	0	9	8
231	R:R:I214	R:R:L268	2.85	No	No	0	9	8
232	R:R:I273	R:R:L277	2.85	No	No	0	5	5
233	R:R:I315	R:R:L274	2.85	No	No	0	6	6
234	R:R:I307	R:R:L311	2.85	No	No	0	5	5
235	R:R:C335	R:R:F331	2.79	No	No	0	6	7
236	R:R:A118	R:R:Y63	2.67	No	Yes	0	7	8
237	R:R:H129	R:R:K132	2.62	Yes	No	0	6	5
238	R:R:A70	R:R:W150	2.59	No	Yes	0	8	9
239	R:R:F148	R:R:K144	2.48	No	No	0	3	3
240	R:R:M323	R:R:R328	2.48	No	No	0	8	9
241	R:R:I35	R:R:Y310	2.42	No	Yes	0	7	7
242	R:R:F161	R:R:F162	2.14	No	No	0	5	5
243	R:R:A314	R:R:G39	1.95	No	No	0	8	8
244	R:R:G42	R:R:V41	1.84	No	No	0	8	4
245	R:R:G97	R:R:V96	1.84	No	No	0	5	2
246	R:R:G197	R:R:V201	1.84	No	No	0	4	5
247	R:R:A133	R:R:C137	1.81	No	No	0	7	7
248	R:R:A126	R:R:A133	1.79	No	No	0	8	7
249	R:R:G37	R:R:I40	1.76	No	Yes	0	5	6
250	R:R:G39	R:R:L38	1.71	No	No	0	8	5
251	R:R:G39	R:R:L75	1.71	No	No	0	8	7
252	R:R:C114	R:R:V149	1.71	No	No	0	5	7
253	R:R:A68	R:R:V46	1.7	No	No	0	9	9
254	R:R:A68	R:R:V47	1.7	No	No	0	9	7
255	R:R:A330	R:R:V49	1.7	No	No	0	7	8
256	R:R:D85	R:R:G89	1.68	No	No	0	4	4
257	R:R:A276	R:R:M204	1.61	No	No	0	6	6
258	R:R:T28	R:R:V27	1.59	No	No	0	5	5
259	L:L:H2	R:R:G180	1.59	Yes	No	0	0	3
260	R:R:A77	R:R:L104	1.58	No	No	0	5	4
261	R:R:I177	R:R:S90	1.55	No	No	0	4	5
262	R:R:I205	R:R:V201	1.54	No	No	0	4	5
263	R:R:I205	R:R:V209	1.54	No	No	0	4	5
264	R:R:I319	R:R:V270	1.54	No	No	0	8	7
265	R:R:H129	R:R:P130	1.53	Yes	No	0	6	8
266	R:R:M45	R:R:V41	1.52	No	No	0	7	4
267	R:R:A77	R:R:Q105	1.52	No	No	0	5	7
268	R:R:N167	R:R:S178	1.49	No	No	0	1	4
269	R:R:N186	R:R:S189	1.49	No	No	0	2	3
270	R:R:L292	R:R:V288	1.49	No	No	0	4	4
271	R:R:G97	R:R:Y93	1.45	No	Yes	0	5	6
272	R:R:I83	R:R:L33	1.43	No	No	0	6	3
273	R:R:Q263	R:R:V264	1.43	No	No	0	8	8
274	R:R:K333	R:R:N336	1.4	No	No	0	4	4
275	R:R:R141	R:R:T138	1.29	Yes	No	0	5	8
276	R:R:F148	R:R:F152	1.07	No	No	0	3	3
277	R:R:F219	R:R:R261	1.07	No	Yes	0	5	7
278	R:R:F327	R:R:F331	1.07	Yes	No	0	8	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:I29	4.8725	4	0	5
2	R:R:I40	3.0125	4	0	6
3	R:R:M56	7.965	4	6	8
4	R:R:Y63	7.71	5	0	8
5	R:R:L67	5.41	4	0	9
6	R:R:W91	7.842	5	3	8
7	R:R:Y93	5.054	5	3	6
8	R:R:Y103	10.0125	4	0	6
9	R:R:Y106	10.6117	6	1	5
10	R:R:I109	5.4025	4	1	7
11	R:R:F119	8.74	4	0	9
12	R:R:Y124	8.105	4	7	8
13	R:R:H129	4.865	4	7	6
14	R:R:R141	7.0775	4	0	5
15	R:R:W150	4.085	4	0	9
16	R:R:W160	13.28	4	1	5
17	R:R:Y181	8.23833	6	1	4
18	R:R:R185	7.245	4	1	2
19	R:R:Y192	7.48833	6	1	5
20	R:R:F199	6.165	6	2	5
21	R:R:Y200	9.1725	4	0	8
22	R:R:Y211	8.6725	4	0	9
23	R:R:R261	5.79	4	0	7
24	R:R:W279	12.14	4	1	8
25	R:R:Y282	8.292	5	1	5
26	R:R:R283	10.1125	4	1	6
27	R:R:N289	6.92	4	0	4
28	R:R:Y310	4.705	8	1	7
29	R:R:F327	6.252	5	5	8
30	L:L:?1	6.88125	8	1	0
31	L:L:H2	5.78	7	1	0
32	L:L:?3	8.5175	8	1	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:I35	R:R:Y310	14.3787	2.42	No	Yes	0	7	7
2	R:R:I35	R:R:L311	12.3458	8.56	No	No	0	7	5
3	R:R:I307	R:R:L311	10.3057	2.85	No	No	0	5	5
4	R:R:I40	R:R:L72	12.3458	4.28	Yes	No	0	6	7
5	R:R:L72	R:R:N43	14.3787	15.1	No	No	0	7	9
6	R:R:D71	R:R:N43	16.3755	12.12	No	No	4	9	9
7	R:R:D71	R:R:S313	20.4341	2.94	No	No	0	9	9
8	R:R:L75	R:R:S313	22.4381	7.51	No	No	0	7	9
9	R:R:L75	R:R:Y310	32.3494	3.52	No	Yes	0	7	7
10	R:R:F327	R:R:N321	10.87	8.46	Yes	No	5	8	7
11	R:R:L64	R:R:N321	17.3919	9.61	No	No	0	8	7
12	R:R:F119	R:R:L64	18.3397	7.31	Yes	No	0	9	8
13	R:R:F119	R:R:R123	46.9054	14.97	Yes	No	0	9	9
14	R:R:R123	R:R:Y320	63.6752	6.17	No	No	0	9	9
15	R:R:I116	R:R:Y320	69.0324	7.25	No	No	0	8	9
16	R:R:F275	R:R:I116	73.7963	6.28	No	No	0	9	8
17	R:R:F275	R:R:W279	74.187	20.04	No	Yes	0	9	8
18	R:R:I109	R:R:W279	74.5379	4.7	Yes	Yes	1	7	8
19	L:L:?3	R:R:I109	100	3.93	Yes	Yes	1	0	7
20	L:L:?3	R:R:A78	28.526	4.34	Yes	No	1	0	7
21	R:R:A78	R:R:Y310	28.2727	4	No	Yes	1	7	7
22	L:L:?3	R:R:R306	33.6517	12.28	Yes	No	1	0	5
23	R:R:R306	R:R:Y310	27.6723	7.2	No	Yes	1	5	7
24	R:R:F119	R:R:Y63	30.3201	6.19	Yes	Yes	0	9	8
25	R:R:E122	R:R:Y63	19.5225	13.47	No	Yes	0	8	8
26	R:R:E122	R:R:P59	13.2284	4.72	No	No	0	8	6
27	R:R:P59	R:R:T58	12.1324	5.25	No	No	0	6	7
28	R:R:N61	R:R:T58	11.0219	10.24	No	No	0	9	7
29	R:R:I146	R:R:S66	11.4126	6.19	No	No	0	7	9
30	R:R:S115	R:R:S66	20.7271	4.89	No	No	0	8	9
31	R:R:L67	R:R:S115	22.5683	6.01	Yes	No	0	9	8
32	R:R:I116	R:R:L67	17.0483	7.14	No	Yes	0	8	9
33	R:R:L67	R:R:N316	12.4905	5.49	Yes	No	0	9	9
34	R:R:N312	R:R:N316	12.8812	8.17	No	No	0	9	9
35	R:R:N312	R:R:W279	15.8184	15.82	No	Yes	0	9	8
36	L:L:?3	R:R:Y106	26.4388	6.46	Yes	Yes	1	0	5
37	L:L:?3	L:L:H2	41.2805	4.73	Yes	Yes	1	0	0
38	L:L:H2	R:R:C179	17.439	7.37	Yes	No	0	0	9
39	R:R:C179	R:R:W91	16.6142	15.67	No	Yes	0	9	8
40	L:L:H2	R:R:Y181	10.0995	5.44	Yes	Yes	1	0	4
41	R:R:I109	R:R:R283	25.3102	3.76	Yes	Yes	1	7	6
42	R:R:D195	R:R:R283	16.2163	14.29	No	Yes	0	6	6
43	R:R:D195	R:R:F199	15.095	3.58	No	Yes	0	6	5
44	R:R:R123	R:R:Y211	28.6598	9.26	No	Yes	0	9	9
45	R:R:F196	R:R:V201	10.7397	3.93	No	No	0	6	5
46	R:R:F196	R:R:Y200	17.7609	10.32	No	Yes	0	6	8
47	R:R:R283	R:R:Y200	24.0116	14.4	Yes	Yes	0	6	8
48	R:R:I214	R:R:L268	10.2478	2.85	No	No	0	9	8
49	R:R:L268	R:R:Y211	21.1973	12.89	No	Yes	0	8	9
50	R:R:Y181	R:R:Y188	11.5428	16.88	Yes	No	0	4	5
51	L:L:?3	R:R:Y282	15.1167	15.08	Yes	Yes	1	0	5
52	L:L:?1	R:R:Y282	12.8631	6.27	Yes	Yes	1	0	5
53	L:L:?1	L:L:H2	14.064	4.13	Yes	Yes	1	0	0
54	R:R:L268	R:R:V264	10.0814	2.98	No	No	0	8	8
55	R:R:L218	R:R:R261	13.7783	4.86	No	Yes	0	8	7
56	R:R:V271	R:R:Y320	10.1176	6.31	No	No	0	8	9
57	L:L:?1	R:R:N289	16.8023	10.28	Yes	Yes	0	0	4
58	R:R:P295	R:R:R185	13.7131	2.88	No	Yes	0	1	2
59	R:R:R283	R:R:W279	13.1271	8	Yes	Yes	1	6	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:I109	R:R:V74	9.22	1	Yes	No	7	7	1	2
R:R:A78	R:R:Q105	6.06	1	No	No	7	7	1	1
R:R:A78	R:R:Y310	4	1	No	Yes	7	7	1	2
L:L:?3	R:R:A78	4.34	1	Yes	No	0	7	0	1
R:R:N82	R:R:R306	8.44	1	No	No	6	5	2	1
R:R:N82	R:R:Y310	5.81	1	No	Yes	6	7	2	2
R:R:C179	R:R:W91	15.67	0	No	Yes	9	8	1	2
R:R:T102	R:R:Y106	4.99	1	No	Yes	4	5	1	1
R:R:L164	R:R:T102	7.37	0	No	No	5	4	2	1
L:L:H2	R:R:T102	9.58	1	Yes	No	0	4	0	1
L:L:?3	R:R:Q105	13.45	1	Yes	No	0	7	0	1
R:R:W160	R:R:Y106	36.66	1	Yes	Yes	5	5	2	1
R:R:Y106	R:R:Y181	3.97	1	Yes	Yes	5	4	1	1
R:R:Y106	R:R:Y192	3.97	1	Yes	Yes	5	5	1	1
L:L:H2	R:R:Y106	7.62	1	Yes	Yes	0	5	0	1
L:L:?3	R:R:Y106	6.46	1	Yes	Yes	0	5	0	1
R:R:I109	R:R:W279	4.7	1	Yes	Yes	7	8	1	2
R:R:I109	R:R:R283	3.76	1	Yes	Yes	7	6	1	2
L:L:?3	R:R:I109	3.93	1	Yes	Yes	0	7	0	1
R:R:W160	R:R:Y192	7.72	1	Yes	Yes	5	5	2	1
L:L:H2	R:R:C179	7.37	1	Yes	No	0	9	0	1
R:R:R185	R:R:Y181	7.2	1	Yes	Yes	2	4	1	1
R:R:Y181	R:R:Y188	16.88	1	Yes	No	4	5	1	2
R:R:Y181	R:R:Y192	10.92	1	Yes	Yes	4	5	1	1
L:L:?1	R:R:Y181	5.02	1	Yes	Yes	0	4	0	1
L:L:H2	R:R:Y181	5.44	1	Yes	Yes	0	4	0	1
R:R:R185	R:R:Y192	7.2	1	Yes	Yes	2	5	1	1
L:L:?1	R:R:R185	11.7	1	Yes	Yes	0	2	0	1
R:R:V286	R:R:Y192	11.36	1	No	Yes	6	5	1	1
L:L:?1	R:R:Y192	3.76	1	Yes	Yes	0	5	0	1
R:R:R283	R:R:W279	8	1	Yes	Yes	6	8	2	2
R:R:V286	R:R:Y282	8.83	1	No	Yes	6	5	1	1
R:R:C305	R:R:Y282	4.03	0	No	Yes	5	5	2	1
R:R:I309	R:R:Y282	7.25	1	No	Yes	6	5	1	1
L:L:?1	R:R:Y282	6.27	1	Yes	Yes	0	5	0	1
L:L:?3	R:R:Y282	15.08	1	Yes	Yes	0	5	0	1
R:R:L285	R:R:N289	9.61	0	No	Yes	4	4	2	1
L:L:?1	R:R:V286	7.97	1	Yes	No	0	6	0	1
R:R:F296	R:R:N289	4.83	0	No	Yes	1	4	2	1
L:L:?1	R:R:N289	10.28	1	Yes	Yes	0	4	0	1
L:L:?1	R:R:L302	5.92	1	Yes	No	0	4	0	1
R:R:R306	R:R:Y310	7.2	1	No	Yes	5	7	1	2
L:L:?3	R:R:R306	12.28	1	Yes	No	0	5	0	1
L:L:?3	R:R:I309	7.87	1	Yes	No	0	6	0	1
R:R:N289	R:R:V288	2.96	0	Yes	No	4	4	1	2
R:R:P295	R:R:R185	2.88	0	No	Yes	1	2	2	1
L:L:H2	R:R:G180	1.59	1	Yes	No	0	3	0	1
R:R:A77	R:R:Q105	1.52	0	No	No	5	7	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	7WKD_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.68
Number of Linked Nodes	249
Number of Links	278
Number of Hubs	32
Number of Links mediated by Hubs	130
Number of Communities	7
Number of Nodes involved in Communities	41
Number of Links involved in Communities	60

Path Summary
Number Of Nodes in MetaPath	60
Number Of Links MetaPath	59
Number of Shortest Paths	49577
Length Of Smallest Path	3
Average Path Length	12.675
Length of Longest Path	27
Minimum Path Strength	1.54
Average Path Strength	7.29135
Maximum Path Strength	20.94
Minimum Path Correlation	0.7
Average Path Correlation	0.916577
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	4.16667
Average % Of Corr. Nodes	45.1845
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	40.2766
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• D2 dopamine receptor binding • protein binding • binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • phosphorus-oxygen lyase activity • enzyme regulator activity • cyclase regulator activity • molecular function regulator activity • cyclase activity • adenylate cyclase regulator activity • lyase activity • catalytic activity • adenylate cyclase activity • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • cation binding • magnesium ion binding • metal ion binding • GDP binding • G protein-coupled serotonin receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • D1 dopamine receptor binding • molecular function activator activity • enzyme activator activity • cyclase activator activity • adenylate cyclase activator activity • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • cell communication • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction
Gene Ontology	Biological Process	• cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • cell communication • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • response to hormone • response to chemical • response to endogenous stimulus • response to peptide hormone • response to oxygen-containing compound • response to nitrogen compound • cell division • leukocyte migration • immune system process • mononuclear cell migration • lymphocyte migration • cell migration • T cell migration • cell motility • regulation of steroid biosynthetic process • regulation of cholesterol biosynthetic process • regulation of cholesterol metabolic process • steroid metabolic process • regulation of lipid metabolic process • sterol metabolic process • positive regulation of biological process • cholesterol metabolic process • lipid biosynthetic process • alcohol metabolic process • regulation of primary metabolic process • positive regulation of metabolic process • regulation of small molecule metabolic process • positive regulation of biosynthetic process • positive regulation of lipid metabolic process • small molecule metabolic process • steroid biosynthetic process • positive regulation of cellular process • regulation of biosynthetic process • secondary alcohol biosynthetic process • regulation of alcohol biosynthetic process • small molecule biosynthetic process • regulation of steroid metabolic process • cholesterol biosynthetic process • positive regulation of cholesterol biosynthetic process • primary metabolic process • secondary alcohol metabolic process • positive regulation of steroid biosynthetic process • biosynthetic process • sterol biosynthetic process • positive regulation of lipid biosynthetic process • regulation of sterol biosynthetic process • alcohol biosynthetic process • positive regulation of cholesterol metabolic process • positive regulation of steroid metabolic process • metabolic process • regulation of lipid biosynthetic process • positive regulation of small molecule metabolic process • regulation of metabolic process • positive regulation of alcohol biosynthetic process • positive regulation of sterol biosynthetic process • lipid metabolic process • regulation of cytoskeleton organization • regulation of cellular component organization • microtubule cytoskeleton organization • regulation of mitotic spindle organization • mitotic cell cycle • cellular component organization • cell cycle • cellular component organization or biogenesis • regulation of cell cycle • microtubule cytoskeleton organization involved in mitosis • spindle organization • cell cycle process • regulation of cell cycle process • regulation of microtubule-based process • regulation of spindle organization • regulation of organelle organization • mitotic spindle organization • organelle organization • mitotic cell cycle process • microtubule-based process • cytoskeleton organization • regulation of microtubule cytoskeleton organization • protein localization • positive regulation of protein localization to cell periphery • regulation of localization • protein localization to cell periphery • cellular localization • regulation of protein localization • positive regulation of protein localization to cell cortex • regulation of protein localization to cell periphery • localization • regulation of cellular localization • regulation of protein localization to cell cortex • cellular macromolecule localization • macromolecule localization • positive regulation of protein localization • protein localization to cell cortex • response to ketone • response to prostaglandin • response to lipid • response to alcohol • response to prostaglandin E • cellular response to forskolin • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to alcohol • response to forskolin • cellular response to lipid • cellular response to ketone • developmental process • multicellular organismal process • epithelium development • ectodermal placode morphogenesis • epidermis development • molting cycle process • hair cycle • animal organ development • hair follicle placode formation • tissue development • ectodermal placode formation • anatomical structure morphogenesis • skin development • skin epidermis development • hair follicle development • molting cycle • anatomical structure development • anatomical structure formation involved in morphogenesis • ectodermal placode development • hair cycle process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of smell • cellular response to nitrogen compound • cellular response to peptide hormone stimulus • response to glucagon • cellular response to glucagon stimulus • cellular response to endogenous stimulus • cellular response to hormone stimulus • multicellular organism development • skeletal system development • bone development • system development • regulation of body fluid levels • wound healing • homotypic cell-cell adhesion • cell activation • hemostasis • platelet aggregation • blood coagulation • cell adhesion • cell-cell adhesion • response to stress • coagulation • regulation of biological quality • response to wounding • platelet activation • response to fluid shear stress • vascular endothelial cell response to laminar fluid shear stress • response to laminar fluid shear stress • cellular response to stress • cellular response to laminar fluid shear stress • vascular endothelial cell response to fluid shear stress • cellular response to fluid shear stress • cognition • developmental growth • growth • cellular response to prostaglandin stimulus • cellular response to prostaglandin E stimulus • adenylate cyclase-activating G protein-coupled receptor signaling pathway • homeostatic process • adaptive thermogenesis • multicellular organismal-level homeostasis • regulation of cold-induced thermogenesis • cold-induced thermogenesis • temperature homeostasis • positive regulation of cold-induced thermogenesis • positive regulation of multicellular organismal process • regulation of multicellular organismal process • establishment of protein localization • nitrogen compound transport • regulation of peptide hormone secretion • regulation of hormone levels • establishment of protein localization to extracellular region • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • regulation of hormone secretion • regulation of peptide secretion • transport • hormone secretion • protein localization to extracellular region • peptide secretion • regulation of secretion by cell • secretion by cell • amide transport • signal release • regulation of signaling • regulation of transport • secretion • regulation of peptide transport • regulation of establishment of protein localization • export from cell • cell-cell signaling • regulation of protein transport • peptide transport • protein transport • regulation of insulin secretion • peptide hormone secretion • hormone transport • regulation of cell communication • insulin secretion • adenylate cyclase-activating adrenergic receptor signaling pathway • adrenergic receptor signaling pathway • establishment of localization in cell • intracellular transport • regulation of defense response • regulation of response to external stimulus • negative regulation of inflammatory response • negative regulation of biological process • inflammatory response to antigenic stimulus • regulation of response to stress • regulation of immune system process • negative regulation of inflammatory response to antigenic stimulus • defense response • immune response • negative regulation of response to stimulus • negative regulation of immune response • regulation of inflammatory response to antigenic stimulus • response to external stimulus • regulation of inflammatory response • regulation of response to stimulus • negative regulation of immune system process • negative regulation of response to external stimulus • negative regulation of defense response • regulation of immune response • inflammatory response • positive regulation of adenylate cyclase activity • positive regulation of molecular function • regulation of molecular function • positive regulation of cyclase activity • activation of adenylate cyclase activity • regulation of adenylate cyclase activity • regulation of catalytic activity • positive regulation of catalytic activity • positive regulation of lyase activity • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • cellular response to monoamine stimulus • renal system process • chemical homeostasis • multicellular organismal-level water homeostasis • multicellular organismal-level chemical homeostasis • renal water homeostasis • midbody • cellular anatomical structure • membrane-bounded organelle • intracellular anatomical structure • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • intracellular membrane-bounded organelle • nucleolus • intracellular organelle lumen • intracellular organelle • organelle lumen • organelle • membraneless organelle
Gene Ontology	Cellular Component	• midbody • cellular anatomical structure • membrane-bounded organelle • intracellular anatomical structure • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • intracellular membrane-bounded organelle • nucleolus • intracellular organelle lumen • intracellular organelle • organelle lumen • organelle • membraneless organelle • nuclear lumen • cell periphery • cell cortex • cytoplasm • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular region • extracellular space • vesicle • extracellular membrane-bounded organelle • centrosome • microtubule organizing center • cytoskeleton • microtubule cytoskeleton • centriolar satellite • cytosol • nucleoplasm • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • organelle membrane • lysosome • Golgi apparatus • endomembrane system • cilium • plasma membrane bounded cell projection • ciliary basal body • cell projection • Golgi apparatus subcompartment • organelle subcompartment • trans-Golgi network membrane • trans-Golgi network • protein binding • binding • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular process • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • signal transduction • cell communication • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • response to oxygen-containing compound • cellular response to oxygen-containing compound • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to chemical stimulus • cellular response to alcohol • response to hormone • response to chemical • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • photoreceptor cell cilium • synapse • cell junction • G-protein beta-subunit binding • fibroblast proliferation • molecular transducer activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • thyrotropin-releasing hormone receptor activity
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	PCA
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	PCA
Name	Pidolic acid
Synonyms	5-Pyrrolidone-2-carboxylic acid
Identifier
Formula	C5 H7 N O3
Molecular Weight	129.114
SMILES
PubChem	7405
Formal Charge	0
Total Atoms	16
Total Chiral Atoms	1
Total Bonds	16
Total Aromatic Bonds	0


Code	LPD
PDB Residues	L:L:?3
Environment Details	Open EMBL-EBI Page
Code	LPD
Name	L-PROLINAMIDE
Synonyms
Identifier
Formula	C5 H10 N2 O
Molecular Weight	114.146
SMILES
PubChem	111306
Formal Charge	0
Total Atoms	18
Total Chiral Atoms	1
Total Bonds	18
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P34981
Sequence	>7WKD_nogp_Chain_R V V T I L L V L I I C G L G I V G N I M V V L V V M R T K H M R T P T N C Y L V S L A V A D L M V L V A A G L P N I T D S I Y G S W V Y G Y V G C L C I T Y L Q Y L G I N A S S C S I T A F T I E R Y I A I C H P I K A Q F L C T F S R A K K I I I F V W A F T S L Y C M L W F F L L D L N I S C G Y K I S R N Y Y S P I Y L M D F G V F Y V V P M I L A T V L Y G F I A R I L F L N R K Q V T K M L A V V V I L F A L L W M P Y R T L V V V N S F L S S P F Q E N W F L L F C R I C I Y L N S A I N P V I Y N L M S Q K F R A A F R K L C N Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	7XW9	A	Peptide	Thyrotropin Releasing Hormone	TRH	Homo sapiens	TRH	-	chim(NtGi1L-Gs-CtGq)/β1/γ2	2.7	2022-12-28	10.1038/s41421-022-00477-0
	7XW9 (No Gprot)	A	Peptide	Thyrotropin Releasing Hormone	TRH	Homo sapiens	TRH	-		2.7	2022-12-28	10.1038/s41421-022-00477-0
	7X1U	A	Peptide	Thyrotropin Releasing Hormone	TRH	Homo sapiens	TRH	-	chim(NtGi2L-Gs-CtGq)/β1/γ2	3.19	2022-08-31	10.1038/s41422-022-00646-6
	7X1U (No Gprot)	A	Peptide	Thyrotropin Releasing Hormone	TRH	Homo sapiens	TRH	-		3.19	2022-08-31	10.1038/s41422-022-00646-6
	7X1T	A	Peptide	Thyrotropin Releasing Hormone	TRH	Homo sapiens	Taltirelin	-	chim(NtGi2L-Gs-CtGq)/β1/γ2	3.26	2022-08-31	10.1038/s41422-022-00646-6
	7X1T (No Gprot)	A	Peptide	Thyrotropin Releasing Hormone	TRH	Homo sapiens	Taltirelin	-		3.26	2022-08-31	10.1038/s41422-022-00646-6
	7WKD	A	Peptide	Thyrotropin Releasing Hormone	TRH	Homo sapiens	TRH	-	chim(NtGi1-Gs-CtGq)/β1/γ2	3.01	2022-06-15	10.1038/s41422-022-00641-x
	7WKD (No Gprot)	A	Peptide	Thyrotropin Releasing Hormone	TRH	Homo sapiens	TRH	-		3.01	2022-06-15	10.1038/s41422-022-00641-x

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