Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index Hub Avg Int. Strength Num Of Links Community ConSurf
1R:R:F47 5.808517
2R:R:G57 3.495407
3R:R:V77 4.1675456
4R:R:D79 4.3125408
5R:R:F81 5.6407
6R:R:D89 6.746509
7R:R:F92 7.175617
8R:R:M96 6.992517
9R:R:W109 6.03375838
10R:R:I119 4.86405
11R:R:N125 7.2625425
12R:R:F128 5.802526
13R:R:T129 6.584527
14R:R:R155 7.2825456
15R:R:P199 6.435444
16R:R:D204 8.015442
17R:R:F217 6.3175418
18R:R:Y228 7.222509
19R:R:M235 6.2225468
20R:R:I247 3.28404
21R:R:W269 8.794518
22R:R:Y272 5.964517
23R:R:Y273 6.7325418
24R:R:Q276 8.0175415
25R:R:F289 3.7775404
26R:R:L314 4.6925407
   

Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index Node1 Node2 Recurrence Int. Strength Hub1? Hub2? Community ConSurf1 ConSurf2
1R:R:L287 R:R:T286 10.13911.47NoNo021
2R:R:F289 R:R:T286 15.18941.3YesNo041
3R:R:F289 R:R:L275 34.78826.09YesNo044
4R:R:A296 R:R:L275 39.59491.58NoNo064
5R:R:A296 R:R:Y272 41.99192.67NoYes067
6R:R:Y272 R:R:Y293 16.37512.98YesNo173
7R:R:I297 R:R:Y293 15.42014.84NoNo053
8R:R:F47 R:R:I297 14.25375.02YesNo075
9R:R:F47 R:R:S298 15.69575.28YesNo075
10R:R:F47 R:R:M43 11.07486.22YesNo075
11R:R:F47 R:R:M96 20.22693.73YesYes177
12R:R:C268 R:R:N303 15.34324.72NoNo089
13R:R:N303 R:R:W269 29.83413.56NoYes098
14R:R:F92 R:R:W269 30.8534.01YesYes178
15R:R:F92 R:R:Y301 34.429317.54YesNo177
16R:R:M96 R:R:Y301 38.242615.57YesNo177
17R:R:W269 R:R:Y272 47.81774.82YesYes187
18R:R:G57 R:R:P308 21.74584.06YesNo079
19R:R:N58 R:R:P308 24.110714.66NoNo099
20R:R:D89 R:R:N58 91.10436.73YesNo099
21R:R:D89 R:R:S304 10011.78YesNo099
22R:R:F92 R:R:S304 97.50057.93YesNo079
23R:R:L93 R:R:S304 11.40173NoNo079
24R:R:N58 R:R:S86 76.31225.96NoNo099
25R:R:S86 R:R:V61 41.67158.08NoNo099
26R:R:I82 R:R:V61 40.52434.61NoNo089
27R:R:I62 R:R:S86 39.42193.1NoNo079
28R:R:I62 R:R:I83 35.1925.89NoNo076
29R:R:I82 R:R:Y311 11.933620.55NoNo089
30R:R:D79 R:R:V65 29.37265.84YesNo087
31R:R:I83 R:R:V65 30.98766.14NoNo067
32R:R:D79 R:R:N76 22.36754.04YesNo088
33R:R:I80 R:R:N76 16.81734.25NoNo068
34R:R:I80 R:R:T161 12.07463.04NoNo064
35R:R:N76 R:R:P157 13.65123.26NoNo081
36R:R:I82 R:R:M137 34.55754.37NoNo089
37R:R:F81 R:R:M137 34.67923.73YesNo079
38R:R:D140 R:R:F81 25.09138.36NoYes087
39R:R:D140 R:R:V77 12.68354.38NoYes586
40R:R:D140 R:R:R155 10.472313.1NoYes586
41R:R:D89 R:R:L85 52.60534.07YesNo099
42R:R:I133 R:R:L85 51.40047.14NoNo089
43R:R:I133 R:R:T129 50.39423.04NoYes087
44R:R:D89 R:R:S130 54.16274.42YesNo099
45R:R:S130 R:R:V88 52.95784.85NoNo098
46R:R:T129 R:R:V88 50.38137.93YesNo278
47R:R:N303 R:R:N307 27.29612.26NoNo099
48R:R:D89 R:R:N307 27.78316.73YesNo099
49R:R:F92 R:R:Q127 34.00633.51YesNo178
50R:R:I119 R:R:M99 69.07012.92YesNo056
51R:R:D123 R:R:M99 70.84536.93NoNo066
52R:R:I119 R:R:W109 57.76455.87YesYes058
53R:R:H101 R:R:W109 10.97876.35NoYes348
54R:R:Q102 R:R:W109 19.77823.29NoYes058
55R:R:C194 R:R:W109 13.0367.84NoYes398
56R:R:C194 R:R:T120 10.93383.38NoNo095
57R:R:N125 R:R:T129 49.37515.85YesYes257
58R:R:S171 R:R:T129 49.34956.4NoYes287
59R:R:I175 R:R:N125 43.47248.5NoYes275
60R:R:Y272 R:R:Y273 33.06426.95YesYes178
61R:R:F128 R:R:S174 40.69737.93YesNo265
62R:R:S171 R:R:S174 46.54873.26NoNo285
63R:R:F128 R:R:I175 41.01783.77YesNo267
64R:R:F128 R:R:Q212 72.86423.51YesNo065
65R:R:F217 R:R:Y273 67.57688.25YesYes188
66R:R:F217 R:R:F266 67.78185.36YesNo186
67R:R:F221 R:R:F266 68.480415NoNo066
68R:R:F221 R:R:F265 60.07187.5NoNo069
69R:R:F265 R:R:T131 37.6215.19NoNo098
70R:R:P220 R:R:T131 36.4933.5NoNo098
71R:R:I224 R:R:L134 20.4324.28NoNo088
72R:R:F265 R:R:L134 21.82274.87NoNo098
73R:R:P220 R:R:T135 22.79693.5NoNo097
74R:R:I224 R:R:T135 19.3047.6NoNo087
75R:R:T135 R:R:V223 38.06963.17NoNo076
76R:R:M137 R:R:R141 37.15956.2NoNo099
77R:R:F221 R:R:T225 59.60397.78NoNo065
78R:R:C262 R:R:T225 58.21965.07NoNo085
79R:R:C262 R:R:Y228 57.6944.03NoYes089
80R:R:R141 R:R:Y228 37.04428.23NoYes099
81R:R:I139 R:R:V223 34.95483.07NoNo066
82R:R:I139 R:R:L143 31.82722.85NoNo064
83R:R:L143 R:R:Y142 28.68683.52NoNo048
84R:R:V146 R:R:Y142 15.952112.62NoNo078
85R:R:K156 R:R:P157 10.01731.67NoNo071
86R:R:Q212 R:R:Y211 63.71216.76NoNo053
87R:R:W207 R:R:Y211 64.66062.89NoNo053
88R:R:P177 R:R:W207 20.34225.4NoNo085
89R:R:P177 R:R:T176 16.30463.5NoNo084
90R:R:T176 R:R:W179 12.25413.64NoNo044
91R:R:D204 R:R:W207 40.63327.82YesNo025
92R:R:D204 R:R:P199 20.41276.44YesYes424
93R:R:F187 R:R:G193 13.29873.01NoNo015
94R:R:G193 R:R:Q102 17.63121.64NoNo055
95R:R:Q276 R:R:T209 15.10614.25YesNo055
96R:R:L219 R:R:P220 20.48323.28NoNo059
97R:R:F214 R:R:L219 19.50914.87NoNo045
98R:R:F214 R:R:L215 18.98993.65NoNo044
99R:R:A258 R:R:Y228 39.33224NoYes089
100R:R:I261 R:R:Y228 20.508914.51NoYes089
101R:R:A258 R:R:L232 37.6534.73NoNo085
102R:R:L232 R:R:V254 32.58352.98NoNo057
103R:R:M235 R:R:V254 27.55889.13YesNo087
104R:R:M235 R:R:R250 22.20733.72YesNo686
105R:R:I247 R:R:R250 20.50895.01YesNo046
106R:R:I247 R:R:P241 11.33123.39YesNo043
107R:R:I261 R:R:T257 16.89423.04NoNo088
108R:R:L314 R:R:T257 15.067613.27YesNo078
109R:R:F289 R:R:I282 10.23526.28YesNo043
110R:R:D123 R:R:F92 66.9234.78NoYes167
111R:R:Q127 R:R:Y273 37.69794.51NoYes188
112R:R:L215 R:R:Y211 20.31023.52NoNo043
113R:R:Q276 R:R:Y272 18.810512.4YesYes157
Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


PDB Summary
PDB 8WWI_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.
Net Summary
Imin 2.98
Number of Linked Nodes 268
Number of Links 295
Number of Hubs 26
Number of Links mediated by Hubs 108
Number of Communities 6
Number of Nodes involved in Communities 43
Number of Links involved in Communities 56
Path Summary
Number Of Nodes in MetaPath 114
Number Of Links MetaPath 113
Number of Shortest Paths 52319
Length Of Smallest Path 3
Average Path Length 14.5461
Length of Longest Path 30
Minimum Path Strength 1.225
Average Path Strength 5.9794
Maximum Path Strength 16.555
Minimum Path Correlation 0.7
Average Path Correlation 0.930379
Maximum Path Correlation 0.99
Minimum % Of Corr. Nodes 4.16667
Average % Of Corr. Nodes 52.4028
Maximum % Of Corr. Nodes 100
Minimum Path Hubs % 0
Average Path Hubs % 29.0109
Maximum Path Hubs % 100
AnnotationTypeLinks
Gene OntologyMolecular Function• D2 dopamine receptor binding   • protein binding   • binding   • signaling receptor binding   • G protein-coupled receptor binding   • dopamine receptor binding   • enzyme regulator activity   • adenylate cyclase inhibitor activity   • cyclase regulator activity   • molecular function inhibitor activity   • cyclase inhibitor activity   • molecular function regulator activity   • enzyme inhibitor activity   • adenylate cyclase regulator activity   • guanyl nucleotide binding   • GTP binding   • nucleotide binding   • guanyl ribonucleotide binding   • purine ribonucleotide binding   • purine ribonucleoside triphosphate binding   • nucleoside phosphate binding   • ion binding   • purine nucleotide binding   • anion binding   • heterocyclic compound binding   • carbohydrate derivative binding   • ribonucleotide binding   • small molecule binding   • cation binding   • magnesium ion binding   • metal ion binding   • GDP binding   • G protein-coupled serotonin receptor binding   • protein-containing complex binding   • G-protein beta/gamma-subunit complex binding   • pyrophosphatase activity   • GTPase activity   • G protein activity   • ribonucleoside triphosphate phosphatase activity   • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides   • hydrolase activity   • hydrolase activity, acting on acid anhydrides   • catalytic activity   • cellular response to stimulus   • regulation of biological process   • regulation of cellular process   • response to stimulus   • signaling   • biological regulation   • adenylate cyclase-inhibiting serotonin receptor signaling pathway   • G protein-coupled serotonin receptor signaling pathway   • cell communication   • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway   • adenylate cyclase-modulating G protein-coupled receptor signaling pathway   • G protein-coupled receptor signaling pathway   • cellular process   • signal transduction
Gene OntologyBiological Process• cellular response to stimulus   • regulation of biological process   • regulation of cellular process   • response to stimulus   • signaling   • biological regulation   • adenylate cyclase-inhibiting serotonin receptor signaling pathway   • G protein-coupled serotonin receptor signaling pathway   • cell communication   • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway   • adenylate cyclase-modulating G protein-coupled receptor signaling pathway   • G protein-coupled receptor signaling pathway   • cellular process   • signal transduction   • response to hormone   • response to chemical   • response to endogenous stimulus   • response to peptide hormone   • response to oxygen-containing compound   • response to nitrogen compound   • cell division   • leukocyte migration   • immune system process   • mononuclear cell migration   • lymphocyte migration   • cell migration   • T cell migration   • cell motility   • regulation of steroid biosynthetic process   • regulation of cholesterol biosynthetic process   • regulation of cholesterol metabolic process   • steroid metabolic process   • regulation of lipid metabolic process   • sterol metabolic process   • positive regulation of biological process   • cholesterol metabolic process   • lipid biosynthetic process   • alcohol metabolic process   • regulation of primary metabolic process   • positive regulation of metabolic process   • regulation of small molecule metabolic process   • positive regulation of biosynthetic process   • positive regulation of lipid metabolic process   • small molecule metabolic process   • steroid biosynthetic process   • positive regulation of cellular process   • regulation of biosynthetic process   • secondary alcohol biosynthetic process   • regulation of alcohol biosynthetic process   • small molecule biosynthetic process   • regulation of steroid metabolic process   • cholesterol biosynthetic process   • positive regulation of cholesterol biosynthetic process   • primary metabolic process   • secondary alcohol metabolic process   • positive regulation of steroid biosynthetic process   • biosynthetic process   • sterol biosynthetic process   • positive regulation of lipid biosynthetic process   • regulation of sterol biosynthetic process   • alcohol biosynthetic process   • positive regulation of cholesterol metabolic process   • positive regulation of steroid metabolic process   • metabolic process   • regulation of lipid biosynthetic process   • positive regulation of small molecule metabolic process   • regulation of metabolic process   • positive regulation of alcohol biosynthetic process   • positive regulation of sterol biosynthetic process   • lipid metabolic process   • negative regulation of protein transport   • regulation of localization   • establishment of protein localization   • nitrogen compound transport   • negative regulation of biological process   • negative regulation of transport   • localization   • negative regulation of secretion   • negative regulation of hormone secretion   • negative regulation of secretion by cell   • intracellular protein localization   • regulation of biological quality   • regulation of peptide hormone secretion   • negative regulation of peptide hormone secretion   • regulation of hormone levels   • establishment of protein localization to extracellular region   • negative regulation of establishment of protein localization   • protein secretion   • establishment of localization   • regulation of protein secretion   • regulation of secretion   • negative regulation of protein secretion   • regulation of hormone secretion   • regulation of protein localization   • regulation of peptide secretion   • transport   • negative regulation of signaling   • hormone secretion   • negative regulation of cell communication   • protein localization to extracellular region   • negative regulation of peptide secretion   • peptide secretion   • regulation of secretion by cell   • secretion by cell   • amide transport   • signal release   • negative regulation of cellular process   • negative regulation of protein localization   • regulation of signaling   • regulation of transport   • secretion   • regulation of peptide transport   • regulation of establishment of protein localization   • export from cell   • cell-cell signaling   • regulation of protein transport   • peptide transport   • negative regulation of insulin secretion   • protein transport   • regulation of insulin secretion   • peptide hormone secretion   • macromolecule localization   • hormone transport   • regulation of cell communication   • insulin secretion   • regulation of cytoskeleton organization   • regulation of cellular component organization   • microtubule cytoskeleton organization   • regulation of mitotic spindle organization   • mitotic cell cycle   • cellular component organization   • cell cycle   • cellular component organization or biogenesis   • regulation of cell cycle   • microtubule cytoskeleton organization involved in mitosis   • spindle organization   • cell cycle process   • regulation of cell cycle process   • regulation of microtubule-based process   • regulation of spindle organization   • regulation of organelle organization   • mitotic spindle organization   • organelle organization   • mitotic cell cycle process   • microtubule-based process   • cytoskeleton organization   • regulation of microtubule cytoskeleton organization   • positive regulation of protein localization to cell periphery   • protein localization to cell periphery   • positive regulation of protein localization to cell cortex   • regulation of protein localization to cell periphery   • regulation of protein localization to cell cortex   • positive regulation of protein localization   • protein localization to cell cortex   • response to ketone   • response to prostaglandin   • response to lipid   • response to alcohol   • response to prostaglandin E   • cellular response to forskolin   • cellular response to oxygen-containing compound   • cellular response to chemical stimulus   • cellular response to alcohol   • response to forskolin   • cellular response to lipid   • cellular response to ketone   • midbody   • cellular anatomical structure   • membrane-bounded organelle   • intracellular anatomical structure   • nucleus   • membrane-enclosed lumen   • intracellular membraneless organelle   • intracellular membrane-bounded organelle   • nucleolus   • intracellular organelle lumen   • intracellular organelle   • organelle lumen   • organelle   • membraneless organelle
Gene OntologyCellular Component• midbody   • cellular anatomical structure   • membrane-bounded organelle   • intracellular anatomical structure   • nucleus   • membrane-enclosed lumen   • intracellular membraneless organelle   • intracellular membrane-bounded organelle   • nucleolus   • intracellular organelle lumen   • intracellular organelle   • organelle lumen   • organelle   • membraneless organelle   • nuclear lumen   • cell periphery   • cell cortex   • cytoplasm   • protein-containing complex   • extrinsic component of plasma membrane   • catalytic complex   • plasma membrane protein complex   • cytoplasmic side of membrane   • membrane   • plasma membrane   • membrane protein complex   • heterotrimeric G-protein complex   • side of membrane   • cytoplasmic side of plasma membrane   • GTPase complex   • extrinsic component of membrane   • extrinsic component of cytoplasmic side of plasma membrane   • extracellular exosome   • extracellular vesicle   • extracellular organelle   • extracellular region   • extracellular space   • vesicle   • extracellular membrane-bounded organelle   • centrosome   • microtubule organizing center   • cytoskeleton   • microtubule cytoskeleton   • centriolar satellite   • cytosol   • nucleoplasm   • vacuolar membrane   • lytic vacuole   • vacuole   • lytic vacuole membrane   • bounding membrane of organelle   • lysosomal membrane   • organelle membrane   • lysosome   • Golgi apparatus   • endomembrane system   • cilium   • plasma membrane bounded cell projection   • ciliary basal body   • cell projection   • protein binding   • binding   • enzyme binding   • GTPase binding   • protein-containing complex binding   • pyrophosphatase activity   • GTPase activity   • ribonucleoside triphosphate phosphatase activity   • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides   • hydrolase activity   • hydrolase activity, acting on acid anhydrides   • catalytic activity   • signaling receptor complex adaptor activity   • protein-macromolecule adaptor activity   • molecular adaptor activity   • signaling adaptor activity   • multicellular organismal process   • system process   • sensory perception of chemical stimulus   • sensory perception   • nervous system process   • sensory perception of taste   • developmental process   • sensory organ development   • eye development   • animal organ development   • retina development in camera-type eye   • visual system development   • multicellular organism development   • camera-type eye development   • anatomical structure development   • sensory system development   • system development   • cell population proliferation   • cellular process   • cellular response to stimulus   • regulation of biological process   • regulation of cellular process   • response to stimulus   • signaling   • biological regulation   • signal transduction   • cell communication   • response to ketone   • response to prostaglandin   • response to lipid   • response to endogenous stimulus   • response to alcohol   • cellular response to prostaglandin stimulus   • response to oxygen-containing compound   • cellular response to oxygen-containing compound   • cellular response to endogenous stimulus   • cellular response to prostaglandin E stimulus   • cellular response to chemical stimulus   • cellular response to alcohol   • response to hormone   • response to chemical   • cellular response to lipid   • response to prostaglandin E   • cellular response to ketone   • cellular response to hormone stimulus   • small GTPase-mediated signal transduction   • Ras protein signal transduction   • intracellular signal transduction   • intracellular signaling cassette   • phospholipase C-activating G protein-coupled receptor signaling pathway   • G protein-coupled receptor signaling pathway   • cellular response to nitrogen compound   • response to dopamine   • cellular response to dopamine   • response to monoamine   • response to catecholamine   • adenylate cyclase-activating dopamine receptor signaling pathway   • cellular response to catecholamine stimulus   • G protein-coupled dopamine receptor signaling pathway   • response to nitrogen compound   • adenylate cyclase-activating G protein-coupled receptor signaling pathway   • cellular response to monoamine stimulus   • adenylate cyclase-modulating G protein-coupled receptor signaling pathway   • synaptic signaling   • cellular response to acetylcholine   • cell-cell signaling   • acetylcholine receptor signaling pathway   • postsynaptic signal transduction   • G protein-coupled acetylcholine receptor signaling pathway   • response to acetylcholine   • non-motile cilium   • 9+0 non-motile cilium   • neuron projection   • photoreceptor disc membrane   • photoreceptor outer segment   • photoreceptor cell cilium   • synapse   • cell junction   • G-protein beta-subunit binding   • fibroblast proliferation   • signaling receptor binding   • neuropeptide binding   • peptide binding   • molecular transducer activity   • G protein-coupled receptor activity   • transmembrane signaling receptor activity   • signaling receptor activity   • peptide receptor activity   • G protein-coupled peptide receptor activity   • neuropeptide receptor activity   • melanin-concentrating hormone receptor activity   • protein-hormone receptor activity   • hormone binding   • neuropeptide signaling pathway   • positive regulation of cytosolic calcium ion concentration   • regulation of biological quality   • cell surface receptor signaling pathway   • regulation of localization   • regulation of calcium ion transport   • positive regulation of calcium ion transport   • transport   • regulation of transport   • regulation of monoatomic ion transport   • positive regulation of biological process   • establishment of localization   • calcium ion transport   • metal ion transport   • localization   • positive regulation of transport   • positive regulation of monoatomic ion transport   • monoatomic ion transport   • monoatomic cation transport   • regulation of metal ion transport   • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway   • metabolic process   • generation of precursor metabolites and energy   • behavior   • feeding behavior   • ciliary membrane   • plasma membrane region   • cell projection membrane
SCOP2Domain Identifier• Ras-like P-loop GTPases   • Transducin (heterotrimeric G protein), gamma chain
SCOP2Family Identifier• Ras-like P-loop GTPases   • Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations-• Orientations of Proteins in Membranes database (OPM)   • Protein Data Bank of Transmembrane Proteins (PDBTM)   • MemProtMD


Details about the values in these tables can be found in the corresponding documentation page .
PDBsumOpen PDBsum Page
ChainR
ProteinReceptor
UniProtQ99705
Sequence
>8WWI_nogp_Chain_R
YINIIMPSV FGTICLLGI IGNSTVIFA VVKKSKLHW CNNVPDIFI 
INLSVVDLL FLLGMPFMI HQLMGNGVW HFGETMCTL ITAMDANSQ 
FTSTYILTA MAIDRYLAT VHPISSTKF RKPSVATLV ICLLWALSF 
ISITPVWLY ARLIPFPGG AVGCGIRLP NPDTDLYWF TLYQFFLAF 
ALPFVVITA AYVRILQRM TSSVAPASQ RSIRLRTKR VTRTAIAIC 
LVFFVCWAP YYVLQLTQL SISRPTLTF VYLYNAAIS LGYANSCLN 
PFVYIVLCE TFRKRLVLS V


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  




This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
8WSSAPeptideMelanin Concentrating HormoneMCH1Homo sapiensPro-MCH-Gi1/β1/γ13.012024-06-19doi.org/10.1038/s41421-024-00679-8
8WSS (No Gprot) APeptideMelanin Concentrating HormoneMCH1Homo sapiensPro-MCH-3.012024-06-19doi.org/10.1038/s41421-024-00679-8
8YNSAPeptideMelanin Concentrating HormoneMCH1Homo sapiensSNAP-94847--3.332024-12-18doi.org/10.1038/s41421-024-00754-0
8YNTAPeptideMelanin Concentrating HormoneMCH1Homo sapiensSNAP-94847--3.432024-12-18doi.org/10.1038/s41421-024-00754-0
8WWKAPeptideMelanin Concentrating HormoneMCH1Homo sapiensMCH-Gi1/β1/γ22.612024-11-13doi.org/10.1038/s41421-024-00754-0
8WWK (No Gprot) APeptideMelanin Concentrating HormoneMCH1Homo sapiensMCH-2.612024-11-13doi.org/10.1038/s41421-024-00754-0
8WWLAPeptideMelanin Concentrating HormoneMCH1Homo sapiensMCH-Gi1/β1/γ22.782024-11-13doi.org/10.1038/s41421-024-00754-0
8WWL (No Gprot) APeptideMelanin Concentrating HormoneMCH1Homo sapiensMCH-2.782024-11-13doi.org/10.1038/s41421-024-00754-0
8WWMAPeptideMelanin Concentrating HormoneMCH1Homo sapiensMCH-Gi1/β1/γ22.812024-11-13doi.org/10.1038/s41421-024-00754-0
8WWM (No Gprot) APeptideMelanin Concentrating HormoneMCH1Homo sapiensMCH-2.812024-11-13doi.org/10.1038/s41421-024-00754-0
8WWNAPeptideMelanin Concentrating HormoneMCH1Homo sapiensMCH-Gi1/β1/γ22.652024-11-13doi.org/10.1038/s41421-024-00754-0
8WWN (No Gprot) APeptideMelanin Concentrating HormoneMCH1Homo sapiensMCH-2.652024-11-13doi.org/10.1038/s41421-024-00754-0
8WWHAPeptideMelanin Concentrating HormoneMCH1Homo sapiens--Gi1/β1/γ22.842024-11-13To be published
8WWH (No Gprot) APeptideMelanin Concentrating HormoneMCH1Homo sapiens--2.842024-11-13To be published
8WWIAPeptideMelanin Concentrating HormoneMCH1Homo sapiens--Gi1/β1/γ23.432024-11-13To be published
8WWI (No Gprot) APeptideMelanin Concentrating HormoneMCH1Homo sapiens--3.432024-11-13To be published
8WWJAPeptideMelanin Concentrating HormoneMCH1Homo sapiens--Gi1/β1/γ23.032024-11-13To be published
8WWJ (No Gprot) APeptideMelanin Concentrating HormoneMCH1Homo sapiens--3.032024-11-13To be published




You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 8WWI_nogp.zip



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