psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:I42	R:R:Y38	19.34	No	No	0	6	4
2	R:R:I39	R:R:Y291	3.63	No	No	0	3	3
3	R:R:I42	R:R:V46	3.07	No	No	0	6	5
4	R:R:M43	R:R:P44	3.35	No	No	0	5	5
5	R:R:F47	R:R:M43	6.22	Yes	No	0	7	5
6	R:R:M43	R:R:N294	8.41	No	No	0	5	4
7	R:R:M104	R:R:P44	8.39	No	No	0	5	5
8	R:R:S298	R:R:V46	3.23	No	No	0	5	5
9	R:R:F47	R:R:M96	3.73	Yes	Yes	1	7	7
10	R:R:F47	R:R:I100	8.79	Yes	No	1	7	6
11	R:R:F47	R:R:I297	5.02	Yes	No	0	7	5
12	R:R:F47	R:R:S298	5.28	Yes	No	0	7	5
13	R:R:A302	R:R:I50	3.25	No	No	0	5	7
14	R:R:C51	R:R:M96	6.48	No	Yes	0	6	7
15	R:R:C305	R:R:L53	4.76	No	No	0	8	5
16	R:R:F309	R:R:L53	6.09	No	No	0	6	5
17	R:R:C305	R:R:G54	3.92	No	No	0	8	8
18	R:R:I55	R:R:L90	5.71	No	No	0	6	8
19	R:R:I55	R:R:L93	4.28	No	No	0	6	7
20	R:R:G57	R:R:T60	3.64	Yes	No	0	7	5
21	R:R:G57	R:R:P308	4.06	Yes	No	0	7	9
22	R:R:F309	R:R:G57	4.52	No	Yes	0	6	7
23	R:R:N58	R:R:S86	5.96	No	No	0	9	9
24	R:R:D89	R:R:N58	6.73	Yes	No	0	9	9
25	R:R:N58	R:R:P308	14.66	No	No	0	9	9
26	R:R:I312	R:R:T60	3.04	No	No	0	7	5
27	R:R:L322	R:R:T60	4.42	No	No	0	6	5
28	R:R:I82	R:R:V61	4.61	No	No	0	8	9
29	R:R:S86	R:R:V61	8.08	No	No	0	9	9
30	R:R:I62	R:R:I83	5.89	No	No	0	7	6
31	R:R:I62	R:R:S86	3.1	No	No	0	7	9
32	R:R:I62	R:R:V87	3.07	No	No	0	7	6
33	R:R:F63	R:R:K67	4.96	No	No	0	3	5
34	R:R:A64	R:R:F318	4.16	No	No	0	7	8
35	R:R:D79	R:R:V65	5.84	Yes	No	0	8	7
36	R:R:I83	R:R:V65	6.14	No	No	0	6	7
37	R:R:D79	R:R:K68	4.15	Yes	No	0	8	5
38	R:R:C74	R:R:L71	4.76	No	No	0	8	8
39	R:R:T161	R:R:W73	13.34	No	No	0	4	4
40	R:R:D79	R:R:N76	4.04	Yes	No	0	8	8
41	R:R:I80	R:R:N76	4.25	No	No	0	6	8
42	R:R:N76	R:R:P157	3.26	No	No	0	8	1
43	R:R:P78	R:R:V77	3.53	No	Yes	0	8	6
44	R:R:D140	R:R:V77	4.38	No	Yes	5	8	6
45	R:R:R155	R:R:V77	5.23	Yes	Yes	5	6	6
46	R:R:P157	R:R:V77	3.53	No	Yes	0	1	6
47	R:R:D79	R:R:P78	3.22	Yes	No	0	8	8
48	R:R:A160	R:R:I80	3.25	No	No	0	7	6
49	R:R:I80	R:R:T161	3.04	No	No	0	6	4
50	R:R:F81	R:R:M137	3.73	Yes	No	0	7	9
51	R:R:D140	R:R:F81	8.36	No	Yes	0	8	7
52	R:R:F81	R:R:I164	7.54	Yes	No	0	7	7
53	R:R:I82	R:R:M137	4.37	No	No	0	8	9
54	R:R:I82	R:R:Y311	20.55	No	No	0	8	9
55	R:R:I164	R:R:N84	12.74	No	No	0	7	9
56	R:R:D89	R:R:L85	4.07	Yes	No	0	9	9
57	R:R:I133	R:R:L85	7.14	No	No	0	8	9
58	R:R:T129	R:R:V88	7.93	Yes	No	2	7	8
59	R:R:S130	R:R:V88	4.85	No	No	0	9	8
60	R:R:V88	R:R:W168	3.68	No	No	2	8	9
61	R:R:D89	R:R:S130	4.42	Yes	No	0	9	9
62	R:R:D89	R:R:S304	11.78	Yes	No	0	9	9
63	R:R:D89	R:R:N307	6.73	Yes	No	0	9	9
64	R:R:L91	R:R:M122	5.65	No	No	0	6	5
65	R:R:L91	R:R:S126	4.5	No	No	0	6	8
66	R:R:D123	R:R:F92	4.78	No	Yes	1	6	7
67	R:R:F92	R:R:S126	5.28	Yes	No	0	7	8
68	R:R:F92	R:R:Q127	3.51	Yes	No	1	7	8
69	R:R:F92	R:R:W269	4.01	Yes	Yes	1	7	8
70	R:R:F92	R:R:Y301	17.54	Yes	No	1	7	7
71	R:R:F92	R:R:S304	7.93	Yes	No	0	7	9
72	R:R:L93	R:R:S304	3	No	No	0	7	9
73	R:R:M96	R:R:P97	3.35	Yes	No	0	7	8
74	R:R:I100	R:R:M96	5.83	No	Yes	1	6	7
75	R:R:M96	R:R:Y301	15.57	Yes	No	1	7	7
76	R:R:F111	R:R:F98	4.29	No	No	0	6	6
77	R:R:F98	R:R:I119	6.28	No	Yes	0	6	5
78	R:R:D123	R:R:M99	6.93	No	No	0	6	6
79	R:R:I100	R:R:M104	5.83	No	No	0	6	5
80	R:R:H101	R:R:W109	6.35	No	Yes	3	4	8
81	R:R:H101	R:R:H110	7.17	No	No	0	4	2
82	R:R:F111	R:R:H101	4.53	No	No	3	6	4
83	R:R:Q102	R:R:W109	3.29	No	Yes	0	5	8
84	R:R:L103	R:R:N294	5.49	No	No	0	4	4
85	R:R:H110	R:R:V108	6.92	No	No	0	2	5
86	R:R:A191	R:R:V108	5.09	No	No	0	1	5
87	R:R:F111	R:R:W109	11.02	No	Yes	3	6	8
88	R:R:C116	R:R:W109	6.53	No	Yes	3	9	8
89	R:R:I119	R:R:W109	5.87	Yes	Yes	0	5	8
90	R:R:L184	R:R:W109	4.56	No	Yes	3	5	8
91	R:R:C194	R:R:W109	7.84	No	Yes	3	9	8
92	R:R:E113	R:R:R183	8.14	No	No	0	2	4
93	R:R:E113	R:R:L184	5.3	No	No	0	2	5
94	R:R:I119	R:R:M115	4.37	Yes	No	0	5	6
95	R:R:C116	R:R:L184	3.17	No	No	3	9	5
96	R:R:C116	R:R:C194	7.28	No	No	3	9	9
97	R:R:A182	R:R:T117	5.03	No	No	0	4	6
98	R:R:R183	R:R:T117	3.88	No	No	0	4	6
99	R:R:A182	R:R:T120	5.03	No	No	0	4	5
100	R:R:C194	R:R:T120	3.38	No	No	0	9	5
101	R:R:D123	R:R:Y301	8.05	No	No	1	6	7
102	R:R:A124	R:R:V178	5.09	No	No	0	4	5
103	R:R:N125	R:R:T129	5.85	Yes	Yes	2	5	7
104	R:R:N125	R:R:S171	7.45	Yes	No	2	5	8
105	R:R:F172	R:R:N125	7.25	No	Yes	2	4	5
106	R:R:I175	R:R:N125	8.5	No	Yes	2	7	5
107	R:R:Q127	R:R:W269	13.14	No	Yes	1	8	8
108	R:R:Q127	R:R:Y273	4.51	No	Yes	1	8	8
109	R:R:F128	R:R:Y132	8.25	Yes	No	2	6	6
110	R:R:F128	R:R:S174	7.93	Yes	No	2	6	5
111	R:R:F128	R:R:I175	3.77	Yes	No	2	6	7
112	R:R:F128	R:R:Q212	3.51	Yes	No	0	6	5
113	R:R:A216	R:R:F128	5.55	No	Yes	0	5	6
114	R:R:I133	R:R:T129	3.04	No	Yes	0	8	7
115	R:R:T129	R:R:W168	9.7	Yes	No	2	7	9
116	R:R:S171	R:R:T129	6.4	No	Yes	2	8	7
117	R:R:P220	R:R:T131	3.5	No	No	0	9	8
118	R:R:F265	R:R:T131	5.19	No	No	0	9	8
119	R:R:S174	R:R:Y132	5.09	No	No	2	5	6
120	R:R:I224	R:R:L134	4.28	No	No	0	8	8
121	R:R:F265	R:R:L134	4.87	No	No	0	9	8
122	R:R:P220	R:R:T135	3.5	No	No	0	9	7
123	R:R:T135	R:R:V223	3.17	No	No	0	7	6
124	R:R:I224	R:R:T135	7.6	No	No	0	8	7
125	R:R:M137	R:R:R141	6.2	No	No	0	9	9
126	R:R:A138	R:R:Y228	5.34	No	Yes	0	9	9
127	R:R:I139	R:R:V223	3.07	No	No	0	6	6
128	R:R:D140	R:R:R155	13.1	No	Yes	5	8	6
129	R:R:R141	R:R:Y228	8.23	No	Yes	0	9	9
130	R:R:L143	R:R:Y142	3.52	No	No	0	4	8
131	R:R:V146	R:R:Y142	12.62	No	No	0	7	8
132	R:R:R230	R:R:Y142	10.29	No	No	0	4	8
133	R:R:A144	R:R:R155	5.53	No	Yes	0	8	6
134	R:R:H147	R:R:V146	4.15	No	No	0	6	7
135	R:R:R234	R:R:V146	7.85	No	No	0	6	7
136	R:R:H147	R:R:S150	4.18	No	No	0	6	5
137	R:R:R155	R:R:S151	5.27	Yes	No	0	6	6
138	R:R:K156	R:R:S158	3.06	No	No	0	7	4
139	R:R:K156	R:R:V159	6.07	No	No	0	7	4
140	R:R:S171	R:R:S174	3.26	No	No	2	8	5
141	R:R:F172	R:R:I175	3.77	No	No	2	4	7
142	R:R:P177	R:R:T176	3.5	No	No	0	8	4
143	R:R:T176	R:R:W179	3.64	No	No	0	4	4
144	R:R:P177	R:R:W207	5.4	No	No	0	8	5
145	R:R:L180	R:R:W179	7.97	No	No	0	5	4
146	R:R:L180	R:R:Y181	3.52	No	No	0	5	5
147	R:R:L198	R:R:Y181	4.69	No	No	4	5	5
148	R:R:P199	R:R:Y181	11.13	Yes	No	4	4	5
149	R:R:I185	R:R:P186	3.39	No	No	0	2	2
150	R:R:F187	R:R:I185	7.54	No	No	0	1	2
151	R:R:G195	R:R:I185	3.53	No	No	0	3	2
152	R:R:P186	R:R:R197	5.76	No	No	0	2	3
153	R:R:F187	R:R:P188	4.33	No	No	0	1	3
154	R:R:F187	R:R:G193	3.01	No	No	0	1	5
155	R:R:L198	R:R:P199	3.28	No	Yes	4	5	4
156	R:R:N200	R:R:P199	4.89	No	Yes	4	4	4
157	R:R:D204	R:R:P199	6.44	Yes	Yes	4	2	4
158	R:R:D204	R:R:N200	13.46	Yes	No	4	2	4
159	R:R:D204	R:R:T203	4.34	Yes	No	0	2	3
160	R:R:D204	R:R:W207	7.82	Yes	No	0	2	5
161	R:R:L205	R:R:L280	4.15	No	No	0	5	5
162	R:R:L280	R:R:Y206	3.52	No	No	0	5	3
163	R:R:F208	R:R:Q212	12.88	No	No	0	5	5
164	R:R:Q276	R:R:T209	4.25	Yes	No	0	5	5
165	R:R:Q212	R:R:Y211	6.76	No	No	0	5	3
166	R:R:L215	R:R:Y211	3.52	No	No	0	4	3
167	R:R:F213	R:R:F217	7.5	No	Yes	1	5	8
168	R:R:A218	R:R:F213	4.16	No	No	0	5	5
169	R:R:F213	R:R:Y273	7.22	No	Yes	1	5	8
170	R:R:F214	R:R:L215	3.65	No	No	0	4	4
171	R:R:F214	R:R:L219	4.87	No	No	0	4	5
172	R:R:F217	R:R:F266	5.36	Yes	No	1	8	6
173	R:R:A270	R:R:F217	4.16	No	Yes	1	5	8
174	R:R:F217	R:R:Y273	8.25	Yes	Yes	1	8	8
175	R:R:L219	R:R:P220	3.28	No	No	0	5	9
176	R:R:F221	R:R:T225	7.78	No	No	0	6	5
177	R:R:F221	R:R:F265	7.5	No	No	0	6	9
178	R:R:F221	R:R:F266	15	No	No	0	6	6
179	R:R:C262	R:R:T225	5.07	No	No	0	8	5
180	R:R:A258	R:R:Y228	4	No	Yes	0	8	9
181	R:R:I261	R:R:Y228	14.51	No	Yes	0	8	9
182	R:R:C262	R:R:Y228	4.03	No	Yes	0	8	9
183	R:R:R230	R:R:R234	4.26	No	No	0	4	6
184	R:R:L232	R:R:V254	2.98	No	No	0	5	7
185	R:R:L232	R:R:T255	8.84	No	No	0	5	6
186	R:R:A258	R:R:L232	4.73	No	No	0	8	5
187	R:R:M235	R:R:T236	3.01	Yes	No	6	8	4
188	R:R:M235	R:R:R250	3.72	Yes	No	6	8	6
189	R:R:M235	R:R:T251	9.03	Yes	No	0	8	7
190	R:R:M235	R:R:V254	9.13	Yes	No	0	8	7
191	R:R:R250	R:R:T236	5.17	No	No	6	6	4
192	R:R:S238	R:R:V239	3.23	No	No	0	6	3
193	R:R:P241	R:R:Q244	7.9	No	No	0	3	4
194	R:R:I247	R:R:P241	3.39	Yes	No	0	4	3
195	R:R:Q244	R:R:S246	11.55	No	No	0	4	4
196	R:R:I247	R:R:S246	3.1	Yes	No	0	4	4
197	R:R:I247	R:R:R250	5.01	Yes	No	0	4	6
198	R:R:R253	R:R:R256	3.2	No	No	0	7	7
199	R:R:E316	R:R:R253	5.82	No	No	0	5	7
200	R:R:I261	R:R:T257	3.04	No	No	0	8	8
201	R:R:L314	R:R:T257	13.27	Yes	No	0	7	8
202	R:R:I261	R:R:V310	3.07	No	No	0	8	8
203	R:R:L263	R:R:V267	2.98	No	No	0	5	6
204	R:R:L306	R:R:V264	4.47	No	No	0	6	6
205	R:R:A270	R:R:F266	8.32	No	No	1	5	6
206	R:R:C268	R:R:N303	4.72	No	No	0	8	9
207	R:R:W269	R:R:Y272	4.82	Yes	Yes	1	8	7
208	R:R:G300	R:R:W269	8.44	No	Yes	0	7	8
209	R:R:N303	R:R:W269	13.56	No	Yes	0	9	8
210	R:R:L299	R:R:P271	3.28	No	No	0	8	9
211	R:R:Y272	R:R:Y273	6.95	Yes	Yes	1	7	8
212	R:R:Q276	R:R:Y272	12.4	Yes	Yes	1	5	7
213	R:R:Y272	R:R:Y293	2.98	Yes	No	1	7	3
214	R:R:F289	R:R:L275	6.09	Yes	No	0	4	4
215	R:R:Q276	R:R:Q279	6.4	Yes	No	0	5	3
216	R:R:Q276	R:R:Y293	9.02	Yes	No	1	5	3
217	R:R:I282	R:R:T278	4.56	No	No	0	3	4
218	R:R:F289	R:R:I282	6.28	Yes	No	0	4	3
219	R:R:T286	R:R:T288	6.28	No	No	0	1	3
220	R:R:I297	R:R:Y293	4.84	No	No	0	5	3
221	R:R:L299	R:R:S298	3	No	No	0	8	5
222	R:R:N303	R:R:N307	12.26	No	No	0	9	9
223	R:R:F318	R:R:Y311	12.38	No	No	0	8	9
224	R:R:E316	R:R:R319	11.63	No	No	0	5	8
225	R:R:L324	R:R:R321	9.72	No	No	0	4	5
226	R:R:N294	R:R:V290	2.96	No	No	0	4	3
227	R:R:L277	R:R:T209	2.95	No	No	0	6	5
228	R:R:I119	R:R:M99	2.92	Yes	No	0	5	6
229	R:R:W207	R:R:Y211	2.89	No	No	0	5	3
230	R:R:I139	R:R:L143	2.85	No	No	0	6	4
231	R:R:I196	R:R:L198	2.85	No	No	0	4	5
232	R:R:I39	R:R:N40	2.83	No	No	0	3	4
233	R:R:L118	R:R:M115	2.83	No	No	0	4	6
234	R:R:G112	R:R:W109	2.81	No	Yes	0	7	8
235	R:R:C315	R:R:F318	2.79	No	No	0	8	8
236	R:R:A136	R:R:F81	2.77	No	Yes	0	7	7
237	R:R:L90	R:R:L94	2.77	No	No	0	8	5
238	R:R:A242	R:R:R248	2.77	No	No	0	4	4
239	R:R:A296	R:R:Y272	2.67	No	Yes	0	6	7
240	R:R:F154	R:R:S151	2.64	No	No	0	4	6
241	R:R:A121	R:R:W179	2.59	No	No	0	5	4
242	R:R:L314	R:R:R256	2.43	Yes	No	0	7	7
243	R:R:G189	R:R:G190	2.11	No	No	0	3	4
244	R:R:G95	R:R:P97	2.03	No	No	0	6	8
245	R:R:C51	R:R:G48	1.96	No	No	0	6	3
246	R:R:A240	R:R:P241	1.87	No	No	0	4	3
247	R:R:G107	R:R:V108	1.84	No	No	0	4	5
248	R:R:G193	R:R:V192	1.84	No	No	0	5	4
249	R:R:A302	R:R:C268	1.81	No	No	0	5	8
250	R:R:A138	R:R:A227	1.79	No	No	0	9	7
251	R:R:G57	R:R:I56	1.76	Yes	No	0	7	4
252	R:R:G105	R:R:M104	1.75	No	No	0	4	5
253	R:R:A240	R:R:S237	1.71	No	No	0	4	4
254	R:R:C268	R:R:V264	1.71	No	No	0	8	6
255	R:R:G105	R:R:N106	1.7	No	No	0	4	4
256	R:R:C165	R:R:T161	1.69	No	No	0	4	4
257	R:R:C315	R:R:T317	1.69	No	No	0	8	6
258	R:R:K156	R:R:P157	1.67	No	No	0	7	1
259	R:R:G193	R:R:Q102	1.64	No	No	0	5	5
260	R:R:N200	R:R:P201	1.63	No	No	0	4	3
261	R:R:S237	R:R:S238	1.63	No	No	0	4	6
262	R:R:S45	R:R:V46	1.62	No	No	0	4	5
263	R:R:A242	R:R:I247	1.62	No	Yes	0	4	4
264	R:R:V159	R:R:V163	1.6	No	No	0	4	6
265	R:R:S281	R:R:T278	1.6	No	No	0	4	4
266	R:R:T120	R:R:V178	1.59	No	No	0	5	5
267	R:R:T225	R:R:V229	1.59	No	No	0	5	4
268	R:R:T278	R:R:V274	1.59	No	No	0	4	6
269	R:R:A136	R:R:L167	1.58	No	No	0	7	7
270	R:R:A260	R:R:L314	1.58	No	Yes	0	6	7
271	R:R:A296	R:R:L275	1.58	No	No	0	6	4
272	R:R:C74	R:R:N75	1.57	No	No	0	8	4
273	R:R:I55	R:R:S59	1.55	No	No	0	6	3
274	R:R:I83	R:R:V66	1.54	No	No	0	6	3
275	R:R:I231	R:R:V254	1.54	No	No	0	8	7
276	R:R:H147	R:R:P148	1.53	No	No	0	6	8
277	R:R:I231	R:R:T145	1.52	No	No	0	8	9
278	R:R:I259	R:R:T255	1.52	No	No	0	5	6
279	R:R:M115	R:R:T114	1.51	No	No	0	6	3
280	R:R:L314	R:R:V313	1.49	Yes	No	0	7	7
281	R:R:L280	R:R:T209	1.47	No	No	0	5	5
282	R:R:L287	R:R:T286	1.47	No	No	0	2	1
283	R:R:D202	R:R:T203	1.45	No	No	0	2	3
284	R:R:P285	R:R:R284	1.44	No	No	0	1	2
285	R:R:F289	R:R:P285	1.44	Yes	No	0	4	1
286	R:R:H72	R:R:S69	1.39	No	No	0	7	6
287	R:R:L210	R:R:L277	1.38	No	No	0	4	6
288	R:R:L275	R:R:L292	1.38	No	No	0	4	5
289	R:R:R284	R:R:S283	1.32	No	No	0	2	1
290	R:R:F289	R:R:T286	1.3	Yes	No	0	4	1
291	R:R:F154	R:R:K153	1.24	No	No	0	4	3
292	R:R:L249	R:R:R253	1.21	No	No	0	4	7
293	R:R:Q233	R:R:R230	1.17	No	No	0	3	4
294	R:R:L287	R:R:Y291	1.17	No	No	0	2	3
295	R:R:H72	R:R:W73	1.06	No	No	0	7	4

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:F47	5.808	5	1	7
2	R:R:G57	3.495	4	0	7
3	R:R:V77	4.1675	4	5	6
4	R:R:D79	4.3125	4	0	8
5	R:R:F81	5.6	4	0	7
6	R:R:D89	6.746	5	0	9
7	R:R:F92	7.175	6	1	7
8	R:R:M96	6.992	5	1	7
9	R:R:W109	6.03375	8	3	8
10	R:R:I119	4.86	4	0	5
11	R:R:N125	7.2625	4	2	5
12	R:R:F128	5.802	5	2	6
13	R:R:T129	6.584	5	2	7
14	R:R:R155	7.2825	4	5	6
15	R:R:P199	6.435	4	4	4
16	R:R:D204	8.015	4	4	2
17	R:R:F217	6.3175	4	1	8
18	R:R:Y228	7.222	5	0	9
19	R:R:M235	6.2225	4	6	8
20	R:R:I247	3.28	4	0	4
21	R:R:W269	8.794	5	1	8
22	R:R:Y272	5.964	5	1	7
23	R:R:Y273	6.7325	4	1	8
24	R:R:Q276	8.0175	4	1	5
25	R:R:F289	3.7775	4	0	4
26	R:R:L314	4.6925	4	0	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:L287	R:R:T286	10.1391	1.47	No	No	0	2	1
2	R:R:F289	R:R:T286	15.1894	1.3	Yes	No	0	4	1
3	R:R:F289	R:R:L275	34.7882	6.09	Yes	No	0	4	4
4	R:R:A296	R:R:L275	39.5949	1.58	No	No	0	6	4
5	R:R:A296	R:R:Y272	41.9919	2.67	No	Yes	0	6	7
6	R:R:Y272	R:R:Y293	16.3751	2.98	Yes	No	1	7	3
7	R:R:I297	R:R:Y293	15.4201	4.84	No	No	0	5	3
8	R:R:F47	R:R:I297	14.2537	5.02	Yes	No	0	7	5
9	R:R:F47	R:R:S298	15.6957	5.28	Yes	No	0	7	5
10	R:R:F47	R:R:M43	11.0748	6.22	Yes	No	0	7	5
11	R:R:F47	R:R:M96	20.2269	3.73	Yes	Yes	1	7	7
12	R:R:C268	R:R:N303	15.3432	4.72	No	No	0	8	9
13	R:R:N303	R:R:W269	29.834	13.56	No	Yes	0	9	8
14	R:R:F92	R:R:W269	30.853	4.01	Yes	Yes	1	7	8
15	R:R:F92	R:R:Y301	34.4293	17.54	Yes	No	1	7	7
16	R:R:M96	R:R:Y301	38.2426	15.57	Yes	No	1	7	7
17	R:R:W269	R:R:Y272	47.8177	4.82	Yes	Yes	1	8	7
18	R:R:G57	R:R:P308	21.7458	4.06	Yes	No	0	7	9
19	R:R:N58	R:R:P308	24.1107	14.66	No	No	0	9	9
20	R:R:D89	R:R:N58	91.1043	6.73	Yes	No	0	9	9
21	R:R:D89	R:R:S304	100	11.78	Yes	No	0	9	9
22	R:R:F92	R:R:S304	97.5005	7.93	Yes	No	0	7	9
23	R:R:L93	R:R:S304	11.4017	3	No	No	0	7	9
24	R:R:N58	R:R:S86	76.3122	5.96	No	No	0	9	9
25	R:R:S86	R:R:V61	41.6715	8.08	No	No	0	9	9
26	R:R:I82	R:R:V61	40.5243	4.61	No	No	0	8	9
27	R:R:I62	R:R:S86	39.4219	3.1	No	No	0	7	9
28	R:R:I62	R:R:I83	35.192	5.89	No	No	0	7	6
29	R:R:I82	R:R:Y311	11.9336	20.55	No	No	0	8	9
30	R:R:D79	R:R:V65	29.3726	5.84	Yes	No	0	8	7
31	R:R:I83	R:R:V65	30.9876	6.14	No	No	0	6	7
32	R:R:D79	R:R:N76	22.3675	4.04	Yes	No	0	8	8
33	R:R:I80	R:R:N76	16.8173	4.25	No	No	0	6	8
34	R:R:I80	R:R:T161	12.0746	3.04	No	No	0	6	4
35	R:R:N76	R:R:P157	13.6512	3.26	No	No	0	8	1
36	R:R:I82	R:R:M137	34.5575	4.37	No	No	0	8	9
37	R:R:F81	R:R:M137	34.6792	3.73	Yes	No	0	7	9
38	R:R:D140	R:R:F81	25.0913	8.36	No	Yes	0	8	7
39	R:R:D140	R:R:V77	12.6835	4.38	No	Yes	5	8	6
40	R:R:D140	R:R:R155	10.4723	13.1	No	Yes	5	8	6
41	R:R:D89	R:R:L85	52.6053	4.07	Yes	No	0	9	9
42	R:R:I133	R:R:L85	51.4004	7.14	No	No	0	8	9
43	R:R:I133	R:R:T129	50.3942	3.04	No	Yes	0	8	7
44	R:R:D89	R:R:S130	54.1627	4.42	Yes	No	0	9	9
45	R:R:S130	R:R:V88	52.9578	4.85	No	No	0	9	8
46	R:R:T129	R:R:V88	50.3813	7.93	Yes	No	2	7	8
47	R:R:N303	R:R:N307	27.296	12.26	No	No	0	9	9
48	R:R:D89	R:R:N307	27.7831	6.73	Yes	No	0	9	9
49	R:R:F92	R:R:Q127	34.0063	3.51	Yes	No	1	7	8
50	R:R:I119	R:R:M99	69.0701	2.92	Yes	No	0	5	6
51	R:R:D123	R:R:M99	70.8453	6.93	No	No	0	6	6
52	R:R:I119	R:R:W109	57.7645	5.87	Yes	Yes	0	5	8
53	R:R:H101	R:R:W109	10.9787	6.35	No	Yes	3	4	8
54	R:R:Q102	R:R:W109	19.7782	3.29	No	Yes	0	5	8
55	R:R:C194	R:R:W109	13.036	7.84	No	Yes	3	9	8
56	R:R:C194	R:R:T120	10.9338	3.38	No	No	0	9	5
57	R:R:N125	R:R:T129	49.3751	5.85	Yes	Yes	2	5	7
58	R:R:S171	R:R:T129	49.3495	6.4	No	Yes	2	8	7
59	R:R:I175	R:R:N125	43.4724	8.5	No	Yes	2	7	5
60	R:R:Y272	R:R:Y273	33.0642	6.95	Yes	Yes	1	7	8
61	R:R:F128	R:R:S174	40.6973	7.93	Yes	No	2	6	5
62	R:R:S171	R:R:S174	46.5487	3.26	No	No	2	8	5
63	R:R:F128	R:R:I175	41.0178	3.77	Yes	No	2	6	7
64	R:R:F128	R:R:Q212	72.8642	3.51	Yes	No	0	6	5
65	R:R:F217	R:R:Y273	67.5768	8.25	Yes	Yes	1	8	8
66	R:R:F217	R:R:F266	67.7818	5.36	Yes	No	1	8	6
67	R:R:F221	R:R:F266	68.4804	15	No	No	0	6	6
68	R:R:F221	R:R:F265	60.0718	7.5	No	No	0	6	9
69	R:R:F265	R:R:T131	37.621	5.19	No	No	0	9	8
70	R:R:P220	R:R:T131	36.493	3.5	No	No	0	9	8
71	R:R:I224	R:R:L134	20.432	4.28	No	No	0	8	8
72	R:R:F265	R:R:L134	21.8227	4.87	No	No	0	9	8
73	R:R:P220	R:R:T135	22.7969	3.5	No	No	0	9	7
74	R:R:I224	R:R:T135	19.304	7.6	No	No	0	8	7
75	R:R:T135	R:R:V223	38.0696	3.17	No	No	0	7	6
76	R:R:M137	R:R:R141	37.1595	6.2	No	No	0	9	9
77	R:R:F221	R:R:T225	59.6039	7.78	No	No	0	6	5
78	R:R:C262	R:R:T225	58.2196	5.07	No	No	0	8	5
79	R:R:C262	R:R:Y228	57.694	4.03	No	Yes	0	8	9
80	R:R:R141	R:R:Y228	37.0442	8.23	No	Yes	0	9	9
81	R:R:I139	R:R:V223	34.9548	3.07	No	No	0	6	6
82	R:R:I139	R:R:L143	31.8272	2.85	No	No	0	6	4
83	R:R:L143	R:R:Y142	28.6868	3.52	No	No	0	4	8
84	R:R:V146	R:R:Y142	15.9521	12.62	No	No	0	7	8
85	R:R:K156	R:R:P157	10.0173	1.67	No	No	0	7	1
86	R:R:Q212	R:R:Y211	63.7121	6.76	No	No	0	5	3
87	R:R:W207	R:R:Y211	64.6606	2.89	No	No	0	5	3
88	R:R:P177	R:R:W207	20.3422	5.4	No	No	0	8	5
89	R:R:P177	R:R:T176	16.3046	3.5	No	No	0	8	4
90	R:R:T176	R:R:W179	12.2541	3.64	No	No	0	4	4
91	R:R:D204	R:R:W207	40.6332	7.82	Yes	No	0	2	5
92	R:R:D204	R:R:P199	20.4127	6.44	Yes	Yes	4	2	4
93	R:R:F187	R:R:G193	13.2987	3.01	No	No	0	1	5
94	R:R:G193	R:R:Q102	17.6312	1.64	No	No	0	5	5
95	R:R:Q276	R:R:T209	15.1061	4.25	Yes	No	0	5	5
96	R:R:L219	R:R:P220	20.4832	3.28	No	No	0	5	9
97	R:R:F214	R:R:L219	19.5091	4.87	No	No	0	4	5
98	R:R:F214	R:R:L215	18.9899	3.65	No	No	0	4	4
99	R:R:A258	R:R:Y228	39.3322	4	No	Yes	0	8	9
100	R:R:I261	R:R:Y228	20.5089	14.51	No	Yes	0	8	9
101	R:R:A258	R:R:L232	37.653	4.73	No	No	0	8	5
102	R:R:L232	R:R:V254	32.5835	2.98	No	No	0	5	7
103	R:R:M235	R:R:V254	27.5588	9.13	Yes	No	0	8	7
104	R:R:M235	R:R:R250	22.2073	3.72	Yes	No	6	8	6
105	R:R:I247	R:R:R250	20.5089	5.01	Yes	No	0	4	6
106	R:R:I247	R:R:P241	11.3312	3.39	Yes	No	0	4	3
107	R:R:I261	R:R:T257	16.8942	3.04	No	No	0	8	8
108	R:R:L314	R:R:T257	15.0676	13.27	Yes	No	0	7	8
109	R:R:F289	R:R:I282	10.2352	6.28	Yes	No	0	4	3
110	R:R:D123	R:R:F92	66.923	4.78	No	Yes	1	6	7
111	R:R:Q127	R:R:Y273	37.6979	4.51	No	Yes	1	8	8
112	R:R:L215	R:R:Y211	20.3102	3.52	No	No	0	4	3
113	R:R:Q276	R:R:Y272	18.8105	12.4	Yes	Yes	1	5	7

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 8WWI_nogp

PDB Summary
PDB	8WWI_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	2.98
Number of Linked Nodes	268
Number of Links	295
Number of Hubs	26
Number of Links mediated by Hubs	108
Number of Communities	6
Number of Nodes involved in Communities	43
Number of Links involved in Communities	56

Path Summary
Number Of Nodes in MetaPath	114
Number Of Links MetaPath	113
Number of Shortest Paths	52319
Length Of Smallest Path	3
Average Path Length	14.5461
Length of Longest Path	30
Minimum Path Strength	1.225
Average Path Strength	5.9794
Maximum Path Strength	16.555
Minimum Path Correlation	0.7
Average Path Correlation	0.930379
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	4.16667
Average % Of Corr. Nodes	52.4028
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	29.0109
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• protein binding • binding • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development
Gene Ontology	Biological Process	• multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular process • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • signal transduction • cell communication • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • response to oxygen-containing compound • cellular response to oxygen-containing compound • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to chemical stimulus • cellular response to alcohol • response to hormone • response to chemical • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex
Gene Ontology	Cellular Component	• cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • membrane-bounded organelle • extracellular vesicle • extracellular organelle • extracellular region • organelle • extracellular space • vesicle • extracellular membrane-bounded organelle • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection • photoreceptor cell cilium • organelle membrane • intracellular anatomical structure • cytoplasm • cytosol • vacuolar membrane • lytic vacuole • vacuole • intracellular membrane-bounded organelle • intracellular organelle • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome • synapse • cell junction • protein binding • binding • G-protein beta-subunit binding • fibroblast proliferation • cell population proliferation • cellular process • cellular response to nitrogen compound • cellular response to stimulus • response to dopamine • regulation of cellular process • response to stimulus • signaling • cellular response to dopamine • response to monoamine • cell communication • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • signal transduction • regulation of biological process • G protein-coupled dopamine receptor signaling pathway • biological regulation • response to oxygen-containing compound • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to monoamine stimulus • response to chemical • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • response to hormone • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • signaling receptor binding • neuropeptide binding • peptide binding • molecular transducer activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • peptide receptor activity • G protein-coupled peptide receptor activity • neuropeptide receptor activity • melanin-concentrating hormone receptor activity • protein-hormone receptor activity • hormone binding • neuropeptide signaling pathway • positive regulation of cytosolic calcium ion concentration • regulation of biological quality • cell surface receptor signaling pathway • regulation of localization • regulation of calcium ion transport • positive regulation of calcium ion transport • transport • regulation of transport • regulation of monoatomic ion transport • positive regulation of biological process • establishment of localization • calcium ion transport • metal ion transport • localization • positive regulation of transport • positive regulation of monoatomic ion transport • monoatomic ion transport • monoatomic cation transport • regulation of metal ion transport • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • metabolic process • generation of precursor metabolites and energy • behavior • multicellular organismal process • feeding behavior • ciliary membrane • plasma membrane region • cell projection membrane • D2 dopamine receptor binding • G protein-coupled receptor binding • dopamine receptor binding • enzyme regulator activity • adenylate cyclase inhibitor activity • cyclase regulator activity • molecular function inhibitor activity • cyclase inhibitor activity • molecular function regulator activity • enzyme inhibitor activity • adenylate cyclase regulator activity • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • cation binding • magnesium ion binding • metal ion binding • GDP binding • G protein-coupled serotonin receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • response to peptide hormone • cell division • leukocyte migration • immune system process • mononuclear cell migration • lymphocyte migration • cell migration • T cell migration • cell motility • regulation of steroid biosynthetic process • regulation of cholesterol biosynthetic process • regulation of cholesterol metabolic process • steroid metabolic process • regulation of lipid metabolic process • sterol metabolic process • cholesterol metabolic process • lipid biosynthetic process • alcohol metabolic process • regulation of primary metabolic process • positive regulation of metabolic process • regulation of small molecule metabolic process • positive regulation of biosynthetic process • positive regulation of lipid metabolic process • small molecule metabolic process • steroid biosynthetic process • positive regulation of cellular process • regulation of biosynthetic process • secondary alcohol biosynthetic process • regulation of alcohol biosynthetic process • small molecule biosynthetic process • regulation of steroid metabolic process • cholesterol biosynthetic process • positive regulation of cholesterol biosynthetic process • primary metabolic process • secondary alcohol metabolic process • positive regulation of steroid biosynthetic process • biosynthetic process • sterol biosynthetic process • positive regulation of lipid biosynthetic process • regulation of sterol biosynthetic process • alcohol biosynthetic process • positive regulation of cholesterol metabolic process • positive regulation of steroid metabolic process • regulation of lipid biosynthetic process • positive regulation of small molecule metabolic process • regulation of metabolic process • positive regulation of alcohol biosynthetic process • positive regulation of sterol biosynthetic process • lipid metabolic process • response to cytokine • response to chemokine • cytokine-mediated signaling pathway • cellular response to chemokine • chemokine-mediated signaling pathway • response to peptide • cellular response to cytokine stimulus • system process • relaxation of smooth muscle • regulation of system process • regulation of muscle system process • muscle system process • relaxation of muscle • positive regulation of relaxation of smooth muscle • positive regulation of relaxation of muscle • positive regulation of multicellular organismal process • regulation of multicellular organismal process • regulation of relaxation of smooth muscle • regulation of relaxation of muscle • negative regulation of protein transport • establishment of protein localization • nitrogen compound transport • negative regulation of biological process • negative regulation of transport • negative regulation of secretion • negative regulation of hormone secretion • negative regulation of secretion by cell • intracellular protein localization • regulation of peptide hormone secretion • negative regulation of peptide hormone secretion • regulation of hormone levels • establishment of protein localization to extracellular region • negative regulation of establishment of protein localization • protein secretion • regulation of protein secretion • regulation of secretion • negative regulation of protein secretion • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • negative regulation of signaling • hormone secretion • negative regulation of cell communication • protein localization to extracellular region • negative regulation of peptide secretion • peptide secretion • regulation of secretion by cell • secretion by cell • signal release • negative regulation of cellular process • negative regulation of protein localization • regulation of signaling • secretion • regulation of peptide transport • regulation of establishment of protein localization • export from cell • cell-cell signaling • regulation of protein transport • peptide transport • negative regulation of insulin secretion • protein transport • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • hormone transport • regulation of cell communication • insulin secretion • regulation of cytoskeleton organization • regulation of cellular component organization • microtubule cytoskeleton organization • regulation of mitotic spindle organization • mitotic cell cycle • cellular component organization • cell cycle • cellular component organization or biogenesis • regulation of cell cycle • microtubule cytoskeleton organization involved in mitosis • spindle organization • cell cycle process • regulation of cell cycle process • regulation of microtubule-based process • regulation of spindle organization • regulation of organelle organization • mitotic spindle organization • organelle organization • mitotic cell cycle process • microtubule-based process • cytoskeleton organization • regulation of microtubule cytoskeleton organization • positive regulation of protein localization to cell periphery • protein localization to cell periphery • positive regulation of protein localization to cell cortex • regulation of protein localization to cell periphery • regulation of protein localization to cell cortex • positive regulation of protein localization • protein localization to cell cortex • cellular response to forskolin • response to forskolin • midbody • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • nucleolus • intracellular organelle lumen • organelle lumen • membraneless organelle • nuclear lumen • cell cortex • centrosome • microtubule organizing center • cytoskeleton • microtubule cytoskeleton • centriolar satellite • sperm principal piece • 9+2 motile cilium • sperm flagellum • motile cilium • nucleoplasm • Golgi apparatus • endomembrane system • ciliary basal body
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain • Ras-like P-loop GTPases
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain • Ras-like P-loop GTPases
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q99705
Sequence	>8WWI_nogp_Chain_R Y I N I I M P S V F G T I C L L G I I G N S T V I F A V V K K S K L H W C N N V P D I F I I N L S V V D L L F L L G M P F M I H Q L M G N G V W H F G E T M C T L I T A M D A N S Q F T S T Y I L T A M A I D R Y L A T V H P I S S T K F R K P S V A T L V I C L L W A L S F I S I T P V W L Y A R L I P F P G G A V G C G I R L P N P D T D L Y W F T L Y Q F F L A F A L P F V V I T A A Y V R I L Q R M T S S V A P A S Q R S I R L R T K R V T R T A I A I C L V F F V C W A P Y Y V L Q L T Q L S I S R P T L T F V Y L Y N A A I S L G Y A N S C L N P F V Y I V L C E T F R K R L V L S V Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8WSS	A	Peptide	Melanin Concentrating Hormone	MCH1	Homo sapiens	MCH	-	Gi1/β1/γ1	3.01	2024-06-19	doi.org/10.1038/s41421-024-00679-8
	8WSS (No Gprot)	A	Peptide	Melanin Concentrating Hormone	MCH1	Homo sapiens	MCH	-		3.01	2024-06-19	doi.org/10.1038/s41421-024-00679-8
	8YNS	A	Peptide	Melanin Concentrating Hormone	MCH1	Homo sapiens	SNAP-94847	-	-	3.33	2024-12-18	doi.org/10.1038/s41421-024-00754-0
	8YNT	A	Peptide	Melanin Concentrating Hormone	MCH1	Homo sapiens	SNAP-94847	-	-	3.43	2024-12-18	doi.org/10.1038/s41421-024-00754-0
	8WWH	A	Peptide	Melanin Concentrating Hormone	MCH1	Homo sapiens	-	-	Gi1/β1/γ2	2.84	2024-11-13	To be published
	8WWH (No Gprot)	A	Peptide	Melanin Concentrating Hormone	MCH1	Homo sapiens	-	-		2.84	2024-11-13	To be published
	8WWI	A	Peptide	Melanin Concentrating Hormone	MCH1	Homo sapiens	-	-	Gi1/β1/γ2	3.43	2024-11-13	To be published
	8WWI (No Gprot)	A	Peptide	Melanin Concentrating Hormone	MCH1	Homo sapiens	-	-		3.43	2024-11-13	To be published
	8WWJ	A	Peptide	Melanin Concentrating Hormone	MCH1	Homo sapiens	-	-	Gi1/β1/γ2	3.03	2024-11-13	To be published
	8WWJ (No Gprot)	A	Peptide	Melanin Concentrating Hormone	MCH1	Homo sapiens	-	-		3.03	2024-11-13	To be published
	8WWK	A	Peptide	Melanin Concentrating Hormone	MCH1	Homo sapiens	MCH	-	Gi1/β1/γ2	2.61	2024-11-13	doi.org/10.1038/s41421-024-00754-0
	8WWK (No Gprot)	A	Peptide	Melanin Concentrating Hormone	MCH1	Homo sapiens	MCH	-		2.61	2024-11-13	doi.org/10.1038/s41421-024-00754-0
	8WWL	A	Peptide	Melanin Concentrating Hormone	MCH1	Homo sapiens	MCH	-	Gi1/β1/γ2	2.78	2024-11-13	doi.org/10.1038/s41421-024-00754-0
	8WWL (No Gprot)	A	Peptide	Melanin Concentrating Hormone	MCH1	Homo sapiens	MCH	-		2.78	2024-11-13	doi.org/10.1038/s41421-024-00754-0
	8WWM	A	Peptide	Melanin Concentrating Hormone	MCH1	Homo sapiens	MCH	-	Gi1/β1/γ2	2.81	2024-11-13	doi.org/10.1038/s41421-024-00754-0
	8WWM (No Gprot)	A	Peptide	Melanin Concentrating Hormone	MCH1	Homo sapiens	MCH	-		2.81	2024-11-13	doi.org/10.1038/s41421-024-00754-0
	8WWN	A	Peptide	Melanin Concentrating Hormone	MCH1	Homo sapiens	MCH	-	Gi1/β1/γ2	2.65	2024-11-13	doi.org/10.1038/s41421-024-00754-0
	8WWN (No Gprot)	A	Peptide	Melanin Concentrating Hormone	MCH1	Homo sapiens	MCH	-		2.65	2024-11-13	doi.org/10.1038/s41421-024-00754-0

there is no ligand in network 8WWI_nogp

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Data downloads are temporarily suspended for technical reasons.
We apologize for the inconvenience.