psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:F41	R:R:I287	7.54	No	No	0	4	5
2	R:R:C43	R:R:F88	4.19	No	Yes	1	4	7
3	R:R:C43	R:R:T92	3.38	No	No	1	4	7
4	R:R:L44	R:R:V47	4.47	No	No	0	5	6
5	R:R:L45	R:R:T291	7.37	No	No	0	7	5
6	R:R:C294	R:R:L45	4.76	No	No	0	7	7
7	R:R:F46	R:R:V85	5.24	Yes	No	0	7	6
8	R:R:F46	R:R:P89	7.22	Yes	No	0	7	8
9	R:R:C294	R:R:F48	6.98	No	No	0	7	5
10	R:R:N53	R:R:S49	4.47	Yes	No	0	9	8
11	R:R:S49	R:R:V85	8.08	No	No	0	8	6
12	R:R:C294	R:R:S49	6.89	No	No	0	7	8
13	R:R:D81	R:R:N53	8.08	Yes	Yes	0	9	9
14	R:R:L82	R:R:N53	4.12	No	Yes	0	7	9
15	R:R:N53	R:R:P297	9.77	Yes	No	0	9	9
16	R:R:L60	R:R:V56	2.98	No	No	4	7	9
17	R:R:L74	R:R:V56	4.47	No	No	4	8	9
18	R:R:A78	R:R:V56	3.39	No	No	0	9	9
19	R:R:I57	R:R:V61	3.07	Yes	No	5	7	4
20	R:R:I57	R:R:L75	5.71	Yes	No	5	7	6
21	R:R:A78	R:R:I57	3.25	No	Yes	0	9	7
22	R:R:L58	R:R:V62	7.45	No	No	0	3	5
23	R:R:F307	R:R:V59	9.18	Yes	No	0	8	7
24	R:R:D71	R:R:L60	4.07	No	No	0	8	7
25	R:R:L60	R:R:L74	4.15	No	No	4	7	8
26	R:R:L75	R:R:V61	4.47	No	No	5	6	4
27	R:R:C63	R:R:K65	6.47	No	No	0	5	6
28	R:R:H310	R:R:K65	14.41	No	No	0	4	6
29	R:R:L66	R:R:V72	2.98	No	No	0	6	6
30	R:R:L66	R:R:L75	4.15	No	No	0	6	6
31	R:R:I69	R:R:S68	3.1	Yes	No	0	6	7
32	R:R:S68	R:R:T70	3.2	No	No	0	7	8
33	R:R:I69	R:R:Y73	9.67	Yes	Yes	2	6	7
34	R:R:D130	R:R:I69	7	No	Yes	2	8	6
35	R:R:I69	R:R:R145	5.01	Yes	Yes	2	6	7
36	R:R:G150	R:R:I69	3.53	No	Yes	2	7	6
37	R:R:D71	R:R:K306	6.91	No	No	0	8	6
38	R:R:L126	R:R:Y73	7.03	No	Yes	2	7	7
39	R:R:M127	R:R:Y73	4.79	No	Yes	0	9	7
40	R:R:D130	R:R:Y73	6.9	No	Yes	2	8	7
41	R:R:G150	R:R:Y73	4.35	No	Yes	2	7	7
42	R:R:L153	R:R:Y73	3.52	No	Yes	2	6	7
43	R:R:A301	R:R:L74	3.15	No	No	0	7	8
44	R:R:F123	R:R:N76	8.46	Yes	No	3	8	9
45	R:R:C154	R:R:N76	9.45	No	No	3	7	9
46	R:R:N76	R:R:W158	3.39	No	Yes	3	9	9
47	R:R:D81	R:R:L77	4.07	Yes	No	0	9	9
48	R:R:L77	R:R:Y300	3.52	No	Yes	0	9	9
49	R:R:S119	R:R:S80	4.89	No	No	3	7	8
50	R:R:F123	R:R:S80	3.96	Yes	No	3	8	8
51	R:R:S80	R:R:W158	6.18	No	Yes	3	8	9
52	R:R:C293	R:R:D81	7.78	Yes	Yes	1	8	9
53	R:R:D81	R:R:N296	8.08	Yes	Yes	1	9	9
54	R:R:F112	R:R:L83	13.4	No	No	0	5	6
55	R:R:F84	R:R:Y113	9.28	Yes	Yes	1	6	6
56	R:R:F84	R:R:G116	3.01	Yes	No	0	6	8
57	R:R:F290	R:R:F84	6.43	Yes	Yes	1	7	6
58	R:R:C293	R:R:F84	6.98	Yes	Yes	1	8	6
59	R:R:S87	R:R:Y113	5.09	No	Yes	0	7	6
60	R:R:F88	R:R:P89	5.78	Yes	No	0	7	8
61	R:R:F88	R:R:T92	5.19	Yes	No	1	7	7
62	R:R:F290	R:R:F88	16.08	Yes	Yes	1	7	7
63	R:R:F90	R:R:W99	11.02	No	No	0	6	9
64	R:R:F90	R:R:V109	5.24	No	No	0	6	5
65	R:R:Q91	R:R:Y113	9.02	No	Yes	0	6	6
66	R:R:D97	R:R:Y94	14.94	No	No	0	4	5
67	R:R:D97	R:R:F101	8.36	No	No	0	4	7
68	R:R:Q98	R:R:W99	15.33	No	No	0	4	9
69	R:R:T103	R:R:V100	3.17	No	No	0	2	3
70	R:R:C106	R:R:C183	5.46	No	No	0	9	9
71	R:R:F112	R:R:V108	5.24	No	No	0	5	5
72	R:R:S110	R:R:Y114	3.82	No	No	0	5	5
73	R:R:Y113	R:R:Y114	11.91	Yes	No	0	6	5
74	R:R:E286	R:R:Y113	5.61	No	Yes	1	5	6
75	R:R:F290	R:R:Y113	3.09	Yes	Yes	1	7	6
76	R:R:M202	R:R:Y114	4.79	No	No	0	5	5
77	R:R:I115	R:R:T165	6.08	No	No	0	5	7
78	R:R:F117	R:R:Y118	11.35	No	Yes	0	8	7
79	R:R:F117	R:R:M121	3.73	No	Yes	1	8	7
80	R:R:F117	R:R:W251	5.01	No	Yes	1	8	9
81	R:R:W122	R:R:Y118	3.86	No	Yes	0	5	7
82	R:R:M202	R:R:Y118	7.18	No	Yes	0	5	7
83	R:R:S119	R:R:W158	8.65	No	Yes	3	7	9
84	R:R:C293	R:R:S120	3.44	Yes	No	0	8	9
85	R:R:M121	R:R:P210	3.35	Yes	Yes	0	7	9
86	R:R:F211	R:R:M121	6.22	Yes	Yes	1	7	7
87	R:R:M121	R:R:W251	10.47	Yes	Yes	1	7	9
88	R:R:T125	R:R:W122	4.85	No	No	0	7	5
89	R:R:P210	R:R:W122	8.11	Yes	No	0	9	5
90	R:R:C154	R:R:F123	6.98	No	Yes	3	7	8
91	R:R:F123	R:R:V157	10.49	Yes	No	0	8	6
92	R:R:F123	R:R:W158	10.02	Yes	Yes	3	8	9
93	R:R:F214	R:R:I124	5.02	Yes	No	0	8	8
94	R:R:I124	R:R:Y300	6.04	No	Yes	0	8	9
95	R:R:L126	R:R:L153	4.15	No	No	2	7	6
96	R:R:L126	R:R:V157	2.98	No	No	0	7	6
97	R:R:M127	R:R:Y300	8.38	No	Yes	0	9	9
98	R:R:F214	R:R:S128	3.96	Yes	No	1	8	9
99	R:R:C217	R:R:S128	5.16	Yes	No	0	7	9
100	R:R:S128	R:R:Y218	5.09	No	Yes	1	9	9
101	R:R:D130	R:R:R145	15.48	No	Yes	2	8	7
102	R:R:R131	R:R:Y218	8.23	No	Yes	0	9	9
103	R:R:R131	R:R:Y300	7.2	No	Yes	0	9	9
104	R:R:L133	R:R:Y132	3.52	No	Yes	0	5	8
105	R:R:V136	R:R:Y132	10.09	No	Yes	6	7	8
106	R:R:H137	R:R:Y132	4.36	No	Yes	6	6	8
107	R:R:C217	R:R:Y132	9.41	Yes	Yes	0	7	8
108	R:R:K220	R:R:Y132	3.58	No	Yes	0	4	8
109	R:R:A134	R:R:R145	6.91	No	Yes	0	8	7
110	R:R:L225	R:R:V135	2.98	No	No	0	8	8
111	R:R:H137	R:R:V136	5.54	No	No	6	6	7
112	R:R:Q224	R:R:V136	5.73	No	No	0	5	7
113	R:R:K143	R:R:Y140	4.78	No	No	0	5	4
114	R:R:V144	R:R:Y140	8.83	No	No	0	4	4
115	R:R:L153	R:R:M149	5.65	No	No	0	6	3
116	R:R:I166	R:R:P167	3.39	No	No	0	4	8
117	R:R:N199	R:R:T198	5.85	No	No	0	5	6
118	R:R:N199	R:R:S262	7.45	No	No	0	5	5
119	R:R:F200	R:R:F259	3.22	No	No	0	5	6
120	R:R:F200	R:R:S262	6.61	No	No	0	5	5
121	R:R:L207	R:R:N203	4.12	Yes	No	1	8	6
122	R:R:N203	R:R:N255	4.09	No	No	1	6	8
123	R:R:F259	R:R:N203	4.83	No	No	0	6	6
124	R:R:G206	R:R:P210	4.06	No	Yes	0	5	9
125	R:R:L207	R:R:L208	4.15	Yes	No	0	8	4
126	R:R:L207	R:R:N255	16.48	Yes	No	1	8	8
127	R:R:I209	R:R:P210	3.39	No	Yes	0	6	9
128	R:R:F211	R:R:F214	5.36	Yes	Yes	1	7	8
129	R:R:F211	R:R:S247	5.28	Yes	No	1	7	9
130	R:R:F211	R:R:W251	6.01	Yes	Yes	1	7	9
131	R:R:F214	R:R:Y218	12.38	Yes	Yes	1	8	9
132	R:R:F214	R:R:S247	7.93	Yes	No	1	8	9
133	R:R:M215	R:R:V244	3.04	No	No	1	4	8
134	R:R:L248	R:R:M215	5.65	No	No	1	6	4
135	R:R:F216	R:R:K220	7.44	No	No	0	4	4
136	R:R:V240	R:R:Y218	8.83	No	Yes	0	7	9
137	R:R:V243	R:R:Y218	5.05	No	Yes	0	8	9
138	R:R:V244	R:R:Y218	5.05	No	Yes	1	8	9
139	R:R:H223	R:R:I219	3.98	No	No	0	3	4
140	R:R:I221	R:R:V240	3.07	No	No	0	8	7
141	R:R:I237	R:R:L222	4.28	No	No	0	7	5
142	R:R:L222	R:R:V240	5.96	No	No	0	5	7
143	R:R:Q224	R:R:R227	5.84	No	No	0	5	5
144	R:R:A236	R:R:L225	3.15	No	No	0	7	8
145	R:R:C228	R:R:K233	3.23	No	No	0	6	6
146	R:R:N232	R:R:Q229	6.6	No	No	0	5	5
147	R:R:K233	R:R:N230	5.6	No	No	0	6	4
148	R:R:R238	R:R:T234	3.88	No	No	0	6	4
149	R:R:K235	R:R:R238	3.71	No	No	0	7	6
150	R:R:K235	R:R:L239	4.23	No	No	0	7	8
151	R:R:E305	R:R:K235	8.1	No	No	0	4	7
152	R:R:L239	R:R:V303	4.47	No	No	0	8	7
153	R:R:L248	R:R:V244	2.98	No	No	1	6	8
154	R:R:L248	R:R:V252	2.98	No	No	0	6	5
155	R:R:F250	R:R:I288	5.02	Yes	No	0	8	7
156	R:R:F250	R:R:H292	13.58	Yes	No	0	8	9
157	R:R:F250	R:R:V295	7.87	Yes	No	0	8	6
158	R:R:F254	R:R:W251	3.01	Yes	Yes	1	7	9
159	R:R:S289	R:R:W251	3.71	No	Yes	1	8	9
160	R:R:H292	R:R:W251	22.22	No	Yes	0	9	9
161	R:R:P253	R:R:V252	3.53	No	No	0	9	5
162	R:R:P253	R:R:T285	3.5	No	No	0	9	6
163	R:R:F254	R:R:L258	3.65	Yes	No	0	7	5
164	R:R:F254	R:R:T285	3.89	Yes	No	0	7	6
165	R:R:E286	R:R:F254	7	No	Yes	1	5	7
166	R:R:F254	R:R:S289	17.18	Yes	No	1	7	8
167	R:R:T285	R:R:V257	7.93	No	No	0	6	5
168	R:R:L258	R:R:T261	2.95	No	No	0	5	4
169	R:R:E286	R:R:F290	10.49	No	Yes	1	5	7
170	R:R:H292	R:R:N296	19.13	No	Yes	0	9	9
171	R:R:C293	R:R:N296	3.15	Yes	Yes	1	8	9
172	R:R:I299	R:R:V295	3.07	No	No	0	8	6
173	R:R:N296	R:R:Y300	5.81	Yes	Yes	0	9	9
174	R:R:A301	R:R:F307	8.32	No	Yes	0	7	8
175	R:R:F302	R:R:F307	11.79	No	Yes	0	6	8
176	R:R:H310	R:R:K306	5.24	No	No	0	4	6
177	R:R:F307	R:R:L311	4.87	Yes	No	0	8	6
178	R:R:D71	R:R:S68	2.94	No	No	0	8	7
179	R:R:I204	R:R:I209	2.94	No	No	0	5	6
180	R:R:I242	R:R:I299	2.94	No	No	0	5	8
181	R:R:Q224	R:R:V135	2.87	No	No	0	5	8
182	R:R:I57	R:R:L79	2.85	Yes	No	0	7	6
183	R:R:I115	R:R:L83	2.85	No	No	0	5	6
184	R:R:I237	R:R:L241	2.85	No	No	0	7	5
185	R:R:I245	R:R:L249	2.85	No	No	0	5	6
186	R:R:L51	R:R:L55	2.77	No	No	0	4	6
187	R:R:A141	R:R:R145	2.77	No	Yes	0	6	7
188	R:R:A246	R:R:F250	2.77	No	Yes	0	6	8
189	R:R:F112	R:R:S87	2.64	No	No	0	5	7
190	R:R:F46	R:R:L50	2.44	Yes	No	0	7	6
191	R:R:F86	R:R:L50	2.44	No	No	0	4	6
192	R:R:F302	R:R:L55	2.44	No	No	0	6	6
193	R:R:F211	R:R:L207	2.44	Yes	Yes	1	7	8
194	R:R:L205	R:R:Y118	2.34	No	Yes	0	5	7
195	R:R:G52	R:R:P297	2.03	No	No	0	8	9
196	R:R:G102	R:R:T103	1.82	No	No	0	8	2
197	R:R:A161	R:R:S119	1.71	No	No	0	8	7
198	R:R:C217	R:R:V129	1.71	Yes	No	0	7	6
199	R:R:K201	R:R:P167	1.67	No	No	0	4	8
200	R:R:C217	R:R:I213	1.64	Yes	No	0	7	7
201	R:R:S87	R:R:V109	1.62	No	No	0	7	5
202	R:R:V104	R:R:V108	1.6	No	No	0	4	5
203	R:R:V252	R:R:V256	1.6	No	No	0	5	6
204	R:R:T151	R:R:V72	1.59	No	No	0	3	6
205	R:R:C228	R:R:L225	1.59	No	No	0	6	8
206	R:R:T151	R:R:T152	1.57	No	No	0	3	3
207	R:R:I147	R:R:V72	1.54	No	No	0	3	6
208	R:R:C228	R:R:Q229	1.53	No	No	0	6	5
209	R:R:M105	R:R:V100	1.52	No	No	0	6	3
210	R:R:I213	R:R:T212	1.52	No	No	0	7	3
211	R:R:I287	R:R:T291	1.52	No	No	0	5	5
212	R:R:M149	R:R:T146	1.51	No	No	0	3	7
213	R:R:L133	R:R:V144	1.49	No	No	0	5	4
214	R:R:L260	R:R:V256	1.49	No	No	0	4	6
215	R:R:I115	R:R:I162	1.47	No	No	0	5	3
216	R:R:I237	R:R:K226	1.45	No	No	0	7	4
217	R:R:I242	R:R:L239	1.43	No	No	0	5	8
218	R:R:K201	R:R:L205	1.41	No	No	0	4	5
219	R:R:E305	R:R:K308	1.35	No	No	0	4	8
220	R:R:L96	R:R:Q98	1.33	No	No	0	4	4
221	R:R:A164	R:R:Y118	1.33	No	Yes	0	5	7
222	R:R:F46	R:R:V47	1.31	Yes	No	0	7	6
223	R:R:H223	R:R:K226	1.31	No	No	0	3	4
224	R:R:F302	R:R:V298	1.31	No	No	0	6	6
225	R:R:R148	R:R:T151	1.29	No	No	0	4	3
226	R:R:H231	R:R:N232	1.28	No	No	0	3	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:F46	4.0525	4	0	7
2	R:R:N53	6.61	4	0	9
3	R:R:I57	3.72	4	5	7
4	R:R:I69	5.662	5	2	6
5	R:R:Y73	6.04333	6	2	7
6	R:R:D81	7.0025	4	1	9
7	R:R:F84	6.425	4	1	6
8	R:R:F88	7.81	4	1	7
9	R:R:Y113	7.33333	6	1	6
10	R:R:Y118	5.212	5	0	7
11	R:R:M121	5.9425	4	1	7
12	R:R:F123	7.982	5	3	8
13	R:R:Y132	6.192	5	6	8
14	R:R:R145	7.5425	4	2	7
15	R:R:W158	7.06	4	3	9
16	R:R:L207	6.7975	4	1	8
17	R:R:P210	4.7275	4	0	9
18	R:R:F211	5.062	5	1	7
19	R:R:F214	6.93	5	1	8
20	R:R:C217	4.48	4	0	7
21	R:R:Y218	7.43833	6	1	9
22	R:R:F250	7.31	4	0	8
23	R:R:W251	8.405	6	1	9
24	R:R:F254	6.946	5	1	7
25	R:R:F290	9.0225	4	1	7
26	R:R:C293	5.3375	4	1	8
27	R:R:N296	9.0425	4	1	9
28	R:R:Y300	6.19	5	0	9
29	R:R:F307	8.54	4	0	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:F46	R:R:V85	14.0069	5.24	Yes	No	0	7	6
2	R:R:S49	R:R:V85	16.468	8.08	No	No	0	8	6
3	R:R:C294	R:R:S49	19.5155	6.89	No	No	0	7	8
4	R:R:C294	R:R:L45	12.9206	4.76	No	No	0	7	7
5	R:R:N53	R:R:S49	37.6658	4.47	Yes	No	0	9	8
6	R:R:D81	R:R:N53	49.8173	8.08	Yes	Yes	0	9	9
7	R:R:D81	R:R:L77	21.9958	4.07	Yes	No	0	9	9
8	R:R:L77	R:R:Y300	22.8129	3.52	No	Yes	0	9	9
9	R:R:M127	R:R:Y300	100	8.38	No	Yes	0	9	9
10	R:R:M127	R:R:Y73	98.8464	4.79	No	Yes	0	9	7
11	R:R:I69	R:R:Y73	66.5353	9.67	Yes	Yes	2	6	7
12	R:R:I69	R:R:S68	60.4788	3.1	Yes	No	0	6	7
13	R:R:D71	R:R:S68	56.8064	2.94	No	No	0	8	7
14	R:R:D71	R:R:L60	47.5774	4.07	No	No	0	8	7
15	R:R:D81	R:R:N296	28.7541	8.08	Yes	Yes	1	9	9
16	R:R:N296	R:R:Y300	65.2855	5.81	Yes	Yes	0	9	9
17	R:R:L60	R:R:V56	26.0623	2.98	No	No	4	7	9
18	R:R:L60	R:R:L74	19.5347	4.15	No	No	4	7	8
19	R:R:A78	R:R:V56	24.9471	3.39	No	No	0	9	9
20	R:R:A78	R:R:I57	22.7745	3.25	No	Yes	0	9	7
21	R:R:I57	R:R:L75	16.0738	5.71	Yes	No	5	7	6
22	R:R:A301	R:R:F307	16.1315	8.32	No	Yes	0	7	8
23	R:R:A301	R:R:L74	18.3619	3.15	No	No	0	7	8
24	R:R:L66	R:R:L75	13.8916	4.15	No	No	0	6	6
25	R:R:L66	R:R:V72	11.6228	2.98	No	No	0	6	6
26	R:R:L126	R:R:Y73	24.9471	7.03	No	Yes	2	7	7
27	R:R:F123	R:R:V157	20.8421	10.49	Yes	No	0	8	6
28	R:R:L126	R:R:V157	23.0533	2.98	No	No	0	7	6
29	R:R:F112	R:R:S87	14.3338	2.64	No	No	0	5	7
30	R:R:S87	R:R:Y113	25.2644	5.09	No	Yes	0	7	6
31	R:R:F84	R:R:Y113	17.7947	9.28	Yes	Yes	1	6	6
32	R:R:C293	R:R:F84	25.1298	6.98	Yes	Yes	1	8	6
33	R:R:F290	R:R:F88	12.0842	16.08	Yes	Yes	1	7	7
34	R:R:E286	R:R:Y113	14.2184	5.61	No	Yes	1	5	6
35	R:R:F117	R:R:W251	14.2569	5.01	No	Yes	1	8	9
36	R:R:H292	R:R:W251	33.8396	22.22	No	Yes	0	9	9
37	R:R:H292	R:R:N296	35.5605	19.13	No	Yes	0	9	9
38	R:R:F117	R:R:Y118	17.0929	11.35	No	Yes	0	8	7
39	R:R:M121	R:R:P210	13.2186	3.35	Yes	Yes	0	7	9
40	R:R:F214	R:R:I124	34.8779	5.02	Yes	No	0	8	8
41	R:R:I124	R:R:Y300	35.3105	6.04	No	Yes	0	8	9
42	R:R:F214	R:R:S128	43.8954	3.96	Yes	No	1	8	9
43	R:R:R131	R:R:Y300	42.7322	7.2	No	Yes	0	9	9
44	R:R:R131	R:R:Y218	42.213	8.23	No	Yes	0	9	9
45	R:R:S128	R:R:Y218	27.3601	5.09	No	Yes	1	9	9
46	R:R:C217	R:R:S128	68.6022	5.16	Yes	No	0	7	9
47	R:R:C217	R:R:Y132	57.7581	9.41	Yes	Yes	0	7	8
48	R:R:L133	R:R:Y132	11.9785	3.52	No	Yes	0	5	8
49	R:R:V136	R:R:Y132	35.8104	10.09	No	Yes	6	7	8
50	R:R:Q224	R:R:V136	33.0033	5.73	No	No	0	5	7
51	R:R:Q224	R:R:V135	27.1102	2.87	No	No	0	5	8
52	R:R:L225	R:R:V135	24.1396	2.98	No	No	0	8	8
53	R:R:F211	R:R:W251	29.004	6.01	Yes	Yes	1	7	9
54	R:R:F211	R:R:L207	17.6408	2.44	Yes	Yes	1	7	8
55	R:R:L207	R:R:N203	11.8727	4.12	Yes	No	1	8	6
56	R:R:V244	R:R:Y218	10.6133	5.05	No	Yes	1	8	9
57	R:R:V240	R:R:Y218	19.0829	8.83	No	Yes	0	7	9
58	R:R:L222	R:R:V240	14.7279	5.96	No	No	0	5	7
59	R:R:I237	R:R:L222	12.3149	4.28	No	No	0	7	5
60	R:R:C228	R:R:L225	18.4484	1.59	No	No	0	6	8
61	R:R:F250	R:R:H292	27.014	13.58	Yes	No	0	8	9
62	R:R:F250	R:R:V295	20.8998	7.87	Yes	No	0	8	6
63	R:R:I299	R:R:V295	18.8233	3.07	No	No	0	8	6
64	R:R:I242	R:R:I299	16.7083	2.94	No	No	0	5	8
65	R:R:I242	R:R:L239	14.9875	1.43	No	No	0	5	8
66	R:R:K235	R:R:L239	10.6999	4.23	No	No	0	7	8
67	R:R:F254	R:R:W251	28.235	3.01	Yes	Yes	1	7	9
68	R:R:C293	R:R:N296	24.4088	3.15	Yes	Yes	1	8	9
69	R:R:E286	R:R:F254	22.14	7	No	Yes	1	5	7
70	R:R:F211	R:R:F214	39.9635	5.36	Yes	Yes	1	7	8
71	R:R:F211	R:R:M121	11.9208	6.22	Yes	Yes	1	7	7

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 8XML_nogp

PDB Summary
PDB	8XML_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	2.95
Number of Linked Nodes	202
Number of Links	226
Number of Hubs	29
Number of Links mediated by Hubs	110
Number of Communities	6
Number of Nodes involved in Communities	48
Number of Links involved in Communities	64

Path Summary
Number Of Nodes in MetaPath	72
Number Of Links MetaPath	71
Number of Shortest Paths	24869
Length Of Smallest Path	3
Average Path Length	12.0331
Length of Longest Path	28
Minimum Path Strength	1.38
Average Path Strength	6.22218
Maximum Path Strength	20.675
Minimum Path Correlation	0.7
Average Path Correlation	0.915423
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	4.54545
Average % Of Corr. Nodes	47.2541
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	43.1867
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain • Ras-like P-loop GTPases
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain • Ras-like P-loop GTPases
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P51685
Sequence	>8XML_nogp_Chain_R V F Y C L L F V F S L L G N S L V I L V L V V C K K L R S I T D V Y L L N L A L S D L L F V F S F P F Q T Y Y L L D Q W V F G T V M C K V V S G F Y Y I G F Y S S M F I T L M S V D R Y L A V V H A V Y A L K V R T I R M G T T L C L A V W L T A I M A T I P L C Y T N F K M N I L G L L I P F T I F M F C Y I K I L H Q L K R C Q N H N K T K A I R L V L I V V I A S L L F W V P F N V V L F L T S T E I I S F T H C C V N P V I Y A F V G E K F K K H L W Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8TLM	A	Protein	Chemokine	CCR8	Homo sapiens	Anti-murine CCR8 antibody	-	-	3.9	2023-12-20	doi.org/10.1038/s41467-023-43601-8
	8U1U	A	Protein	Chemokine	CCR8	Homo sapiens	CCL1	-	Gi1/β1/γ2	3.1	2023-12-20	doi.org/10.1038/s41467-023-43601-8
	8U1U (No Gprot)	A	Protein	Chemokine	CCR8	Homo sapiens	CCL1	-		3.1	2023-12-20	doi.org/10.1038/s41467-023-43601-8
	8KFX	A	Protein	Chemokine	CCR8	Homo sapiens	LMD-009	-	Gi1/β1/γ2	2.96	2024-02-07	doi.org/10.1126/sciadv.adj7500
	8KFX (No Gprot)	A	Protein	Chemokine	CCR8	Homo sapiens	LMD-009	-		2.96	2024-02-07	doi.org/10.1126/sciadv.adj7500
	8KFY	A	Protein	Chemokine	CCR8	Homo sapiens	ZK-756326	-	Gi1/β1/γ2	3.06	2024-02-07	doi.org/10.1126/sciadv.adj7500
	8KFY (No Gprot)	A	Protein	Chemokine	CCR8	Homo sapiens	ZK-756326	-		3.06	2024-02-07	doi.org/10.1126/sciadv.adj7500
	8KFZ	A	Protein	Chemokine	CCR8	Homo sapiens	-	-	Gi1/β1/γ2	3.3	2024-02-07	doi.org/10.1126/sciadv.adj7500
	8KFZ (No Gprot)	A	Protein	Chemokine	CCR8	Homo sapiens	-	-		3.3	2024-02-07	doi.org/10.1126/sciadv.adj7500
	8XML	A	Protein	Chemokine	CCR8	Homo sapiens	-	-	Gi1/β1/γ2	2.58	2025-01-01	To be published
	8XML (No Gprot)	A	Protein	Chemokine	CCR8	Homo sapiens	-	-		2.58	2025-01-01	To be published

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 8XML_nogp.zip

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