psnGPCR

Press and hold down the left mouse button and move the mouse to rotate.
Press and hold down the central mouse button and move the mouse to translate.
Use the mouse wheel to zoom in or out.
Click on any atom on your molecule and the corresponding residue label will be placed beneath the viewer.

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:C1	L:L:C15	7.28	No	No	0	0	0
2	L:L:C1	L:L:D18	6.22	No	Yes	0	0	0
3	L:L:S2	R:R:L257	6.01	No	No	0	0	5
4	L:L:S2	R:R:K270	6.12	No	No	0	0	4
5	L:L:C3	L:L:D8	4.67	No	No	7	0	0
6	L:L:C11	L:L:C3	7.28	No	No	7	0	0
7	L:L:D8	L:L:S5	5.89	No	No	0	0	0
8	L:L:L6	R:R:H258	3.86	No	Yes	4	0	4
9	L:L:L6	R:R:P259	4.93	No	No	4	0	6
10	L:L:L6	R:R:V260	2.98	No	No	4	0	3
11	L:L:C11	L:L:D8	6.22	No	No	7	0	0
12	L:L:E10	R:R:R357	3.49	No	Yes	0	0	5
13	L:L:C11	L:L:F14	4.19	No	Yes	0	0	0
14	L:L:V12	R:R:L252	2.98	No	Yes	0	0	3
15	L:L:L17	L:L:Y13	5.86	No	No	0	0	0
16	L:L:Y13	R:R:Y247	11.91	No	Yes	0	0	2
17	L:L:C15	L:L:F14	6.98	No	Yes	0	0	0
18	L:L:D18	L:L:F14	10.75	Yes	Yes	0	0	0
19	L:L:F14	R:R:K346	8.69	Yes	No	0	0	4
20	L:L:H16	R:R:I254	5.3	No	No	0	0	4
21	L:L:L17	R:R:L365	6.92	No	No	1	0	3
22	L:L:D18	L:L:I19	4.2	Yes	Yes	1	0	0
23	L:L:D18	R:R:R343	10.72	Yes	Yes	0	0	6
24	L:L:D18	R:R:D368	3.99	Yes	No	1	0	4
25	L:L:I19	L:L:W21	3.52	Yes	Yes	1	0	0
26	L:L:I19	R:R:N158	7.08	Yes	No	0	0	7
27	L:L:I19	R:R:D368	15.39	Yes	No	1	0	4
28	L:L:I19	R:R:Y369	3.63	Yes	Yes	1	0	3
29	L:L:I19	R:R:I372	4.42	Yes	No	0	0	6
30	L:L:I20	R:R:N158	8.5	No	No	0	0	7
31	L:L:I20	R:R:V177	3.07	No	Yes	1	0	5
32	L:L:I20	R:R:P178	5.08	No	Yes	1	0	5
33	L:L:W21	R:R:Q181	16.43	Yes	No	1	0	6
34	L:L:W21	R:R:K182	29.01	Yes	No	1	0	4
35	L:L:W21	R:R:V185	4.9	Yes	No	0	0	7
36	L:L:W21	R:R:L277	11.39	Yes	No	0	0	6
37	L:L:W21	R:R:R343	15.99	Yes	Yes	0	0	6
38	R:R:N353	R:R:P88	9.77	No	No	0	1	7
39	R:R:C90	R:R:Q91	6.1	No	No	0	7	4
40	R:R:C358	R:R:C90	7.28	No	No	0	8	7
41	R:R:G92	R:R:P93	4.06	No	No	0	4	4
42	R:R:C358	R:R:P93	3.77	No	No	0	8	4
43	R:R:C358	R:R:I94	3.27	No	No	0	8	4
44	R:R:F100	R:R:I96	5.02	Yes	Yes	1	4	5
45	R:R:I96	R:R:Y369	4.84	Yes	Yes	1	5	3
46	R:R:E98	R:R:K101	16.2	No	Yes	0	3	6
47	R:R:F100	R:R:N104	6.04	Yes	No	1	4	5
48	R:R:F100	R:R:V366	13.11	Yes	No	0	4	1
49	R:R:F100	R:R:Y369	7.22	Yes	Yes	1	4	3
50	R:R:F100	R:R:I370	5.02	Yes	No	0	4	5
51	R:R:K101	R:R:Y102	3.58	Yes	No	0	6	3
52	R:R:N104	R:R:S108	4.47	No	No	1	5	7
53	R:R:N104	R:R:N373	12.26	No	No	1	5	5
54	R:R:S108	R:R:V159	3.23	No	No	0	7	7
55	R:R:N373	R:R:S108	2.98	No	No	1	5	7
56	R:R:S376	R:R:V111	3.23	Yes	No	0	7	8
57	R:R:F112	R:R:V113	6.55	No	No	0	7	5
58	R:R:F112	R:R:I116	8.79	No	No	0	7	7
59	R:R:F112	R:R:I155	3.77	No	Yes	0	7	7
60	R:R:C380	R:R:L114	4.76	No	No	0	8	5
61	R:R:C380	R:R:G115	3.92	No	No	0	8	8
62	R:R:D147	R:R:N119	6.73	No	Yes	0	9	9
63	R:R:L148	R:R:N119	6.87	No	Yes	0	7	9
64	R:R:N119	R:R:P383	3.26	Yes	No	0	9	9
65	R:R:I125	R:R:T121	3.04	Yes	No	0	7	6
66	R:R:F397	R:R:T121	7.78	No	No	0	7	6
67	R:R:L122	R:R:P383	4.93	No	No	0	9	9
68	R:R:F397	R:R:L122	4.87	No	No	0	7	9
69	R:R:A396	R:R:I125	6.5	No	Yes	0	4	7
70	R:R:I126	R:R:N137	7.08	Yes	No	0	7	8
71	R:R:A141	R:R:I126	4.87	No	Yes	0	7	7
72	R:R:K130	R:R:Y127	3.58	No	No	0	6	2
73	R:R:M132	R:R:N129	7.01	No	No	9	7	6
74	R:R:N129	R:R:R392	12.05	No	No	9	6	6
75	R:R:K130	R:R:R133	7.43	No	No	0	6	7
76	R:R:C131	R:R:M132	3.24	No	No	0	5	7
77	R:R:M132	R:R:R392	4.96	No	No	9	7	6
78	R:R:I138	R:R:R133	7.52	No	No	0	6	7
79	R:R:R133	R:R:V214	3.92	No	No	0	7	6
80	R:R:N134	R:R:P136	8.15	No	No	0	8	8
81	R:R:N134	R:R:N137	4.09	No	No	0	8	8
82	R:R:G135	R:R:P136	4.06	No	No	0	7	8
83	R:R:G135	R:R:P215	4.06	No	No	0	7	1
84	R:R:D198	R:R:P136	4.83	No	No	0	8	8
85	R:R:A194	R:R:L139	3.15	No	No	0	7	7
86	R:R:L139	R:R:L195	4.15	No	No	0	7	9
87	R:R:D198	R:R:L139	8.14	No	No	0	8	7
88	R:R:I222	R:R:S142	4.64	No	No	0	7	9
89	R:R:L143	R:R:S191	7.51	No	No	0	9	8
90	R:R:L143	R:R:L192	5.54	No	No	0	9	8
91	R:R:L143	R:R:N382	5.49	No	No	0	9	9
92	R:R:G146	R:R:I187	3.53	No	Yes	0	8	7
93	R:R:D147	R:R:S379	8.83	No	Yes	0	9	9
94	R:R:H150	R:R:S184	9.76	No	No	0	8	8
95	R:R:I151	R:R:S376	6.19	No	Yes	8	6	7
96	R:R:I151	R:R:S379	6.19	No	Yes	8	6	9
97	R:R:I153	R:R:V177	4.61	No	Yes	0	5	5
98	R:R:I153	R:R:I180	8.83	No	No	0	5	5
99	R:R:D154	R:R:I155	7	No	Yes	0	6	7
100	R:R:D154	R:R:N158	12.12	No	No	0	6	7
101	R:R:D154	R:R:I372	8.4	No	No	0	6	6
102	R:R:I155	R:R:P156	3.39	Yes	No	0	7	9
103	R:R:I155	R:R:S376	4.64	Yes	Yes	0	7	7
104	R:R:I157	R:R:W167	4.7	No	Yes	0	6	9
105	R:R:I157	R:R:V177	4.61	No	Yes	0	6	5
106	R:R:L163	R:R:Y160	5.86	No	No	0	4	4
107	R:R:A164	R:R:Y160	6.67	No	No	0	5	4
108	R:R:P168	R:R:Y160	4.17	No	No	0	2	4
109	R:R:K161	R:R:W167	4.64	No	Yes	0	5	9
110	R:R:L162	R:R:Y369	10.55	No	Yes	0	4	3
111	R:R:D166	R:R:R253	9.53	No	No	0	5	5
112	R:R:F169	R:R:W167	5.01	Yes	Yes	0	7	9
113	R:R:C174	R:R:W167	6.53	No	Yes	5	9	9
114	R:R:C255	R:R:W167	7.84	No	Yes	5	9	9
115	R:R:F169	R:R:M173	3.73	Yes	No	0	7	6
116	R:R:M173	R:R:V177	4.56	No	Yes	0	6	5
117	R:R:C174	R:R:I242	6.55	No	No	5	9	5
118	R:R:C174	R:R:C255	7.28	No	No	5	9	9
119	R:R:I180	R:R:L176	5.71	No	No	0	5	5
120	R:R:P178	R:R:V177	3.53	Yes	Yes	1	5	5
121	R:R:P178	R:R:Q181	3.16	Yes	No	1	5	6
122	R:R:F240	R:R:P178	11.56	No	Yes	0	5	5
123	R:R:F179	R:R:I180	3.77	Yes	No	0	6	5
124	R:R:F179	R:R:V230	5.24	Yes	No	0	6	3
125	R:R:A237	R:R:F179	5.55	No	Yes	0	4	6
126	R:R:K182	R:R:Q181	10.85	No	No	1	4	6
127	R:R:A183	R:R:S229	3.42	No	No	0	6	8
128	R:R:V185	R:R:Y281	6.31	No	Yes	0	7	6
129	R:R:V185	R:R:W336	3.68	No	Yes	0	7	8
130	R:R:I187	R:R:W226	7.05	Yes	No	0	7	9
131	R:R:I187	R:R:S229	3.1	Yes	No	0	7	8
132	R:R:P285	R:R:V189	5.3	No	No	0	9	8
133	R:R:I225	R:R:L190	12.85	No	No	0	7	6
134	R:R:F332	R:R:L192	3.65	Yes	No	0	9	8
135	R:R:C193	R:R:S196	3.44	No	No	0	8	9
136	R:R:C193	R:R:I288	3.27	No	No	0	8	7
137	R:R:L195	R:R:R199	14.58	No	No	0	9	9
138	R:R:S196	R:R:T289	6.4	No	No	0	9	8
139	R:R:S196	R:R:Y293	6.36	No	Yes	0	9	9
140	R:R:F292	R:R:I197	10.05	No	No	0	7	6
141	R:R:D198	R:R:R201	3.57	No	No	0	8	5
142	R:R:R199	R:R:Y293	9.26	No	Yes	0	9	9
143	R:R:A204	R:R:Y200	9.34	No	Yes	0	7	8
144	R:R:F292	R:R:Y200	8.25	No	Yes	0	7	8
145	R:R:L295	R:R:Y200	8.21	No	Yes	0	3	8
146	R:R:M296	R:R:Y200	3.59	No	Yes	0	8	8
147	R:R:R201	R:R:W217	12	No	Yes	0	5	5
148	R:R:M296	R:R:V203	3.04	No	No	0	8	9
149	R:R:G211	R:R:K210	3.49	No	No	0	3	4
150	R:R:P215	R:R:V214	3.53	No	No	0	1	6
151	R:R:P215	R:R:T218	12.24	No	No	0	1	7
152	R:R:K216	R:R:W217	10.44	No	Yes	0	3	5
153	R:R:E221	R:R:W217	7.63	No	Yes	0	6	5
154	R:R:I222	R:R:W226	5.87	No	No	0	7	9
155	R:R:L232	R:R:V228	2.98	Yes	No	2	5	4
156	R:R:S229	R:R:V230	4.85	No	No	0	8	3
157	R:R:L232	R:R:V231	2.98	Yes	No	0	5	4
158	R:R:L232	R:R:W276	7.97	Yes	Yes	2	5	4
159	R:R:F280	R:R:L232	7.31	No	Yes	2	5	5
160	R:R:P235	R:R:V234	5.3	Yes	No	0	8	4
161	R:R:E236	R:R:P235	6.29	Yes	Yes	2	5	8
162	R:R:M266	R:R:P235	3.35	Yes	Yes	0	4	8
163	R:R:P235	R:R:Y269	22.25	Yes	Yes	2	8	3
164	R:R:E236	R:R:F240	3.5	Yes	No	0	5	5
165	R:R:E236	R:R:Y269	12.35	Yes	Yes	2	5	3
166	R:R:E236	R:R:K273	5.4	Yes	Yes	2	5	7
167	R:R:I238	R:R:M266	7.29	No	Yes	0	5	4
168	R:R:G239	R:R:Q261	4.93	No	No	0	5	2
169	R:R:F240	R:R:L257	17.05	No	No	0	5	5
170	R:R:D241	R:R:H258	17.65	No	Yes	0	4	4
171	R:R:C255	R:R:I242	6.55	No	No	5	9	5
172	R:R:I243	R:R:M245	10.2	No	No	0	1	1
173	R:R:H258	R:R:I243	6.63	Yes	No	0	4	1
174	R:R:T244	R:R:Y251	9.99	No	No	0	1	5
175	R:R:L252	R:R:M245	8.48	Yes	No	0	3	1
176	R:R:D246	R:R:Y251	6.9	No	No	0	1	5
177	R:R:S250	R:R:Y247	6.36	No	Yes	0	1	2
178	R:R:L252	R:R:Y247	4.69	Yes	Yes	0	3	2
179	R:R:I254	R:R:L252	9.99	No	Yes	0	4	3
180	R:R:I254	R:R:L256	5.71	No	No	0	4	4
181	R:R:L256	R:R:P259	4.93	No	No	0	4	6
182	R:R:H258	R:R:P259	4.58	Yes	No	4	4	6
183	R:R:H258	R:R:V260	6.92	Yes	No	4	4	3
184	R:R:M266	R:R:Q261	4.08	Yes	No	0	4	2
185	R:R:Q261	R:R:Q267	6.4	No	No	0	2	1
186	R:R:K262	R:R:T263	4.5	No	No	0	1	3
187	R:R:M266	R:R:T263	7.53	Yes	No	0	4	3
188	R:R:K273	R:R:Y269	13.14	Yes	Yes	2	7	3
189	R:R:W276	R:R:Y269	10.61	Yes	Yes	2	4	3
190	R:R:A272	R:R:W275	3.89	No	No	0	4	5
191	R:R:D274	R:R:K273	6.91	No	Yes	0	5	7
192	R:R:K273	R:R:W276	10.44	Yes	Yes	2	7	4
193	R:R:K273	R:R:L277	8.46	Yes	No	0	7	6
194	R:R:D274	R:R:R343	10.72	No	Yes	0	5	6
195	R:R:F280	R:R:W276	11.02	No	Yes	2	5	4
196	R:R:W276	R:R:Y281	8.68	Yes	Yes	2	4	6
197	R:R:L277	R:R:Y281	5.86	No	Yes	0	6	6
198	R:R:F278	R:R:F282	3.22	Yes	Yes	3	6	8
199	R:R:F278	R:R:H340	4.53	Yes	No	3	6	8
200	R:R:F278	R:R:I344	3.77	Yes	No	0	6	6
201	R:R:F280	R:R:Y281	16.5	No	Yes	2	5	6
202	R:R:F282	R:R:F332	5.36	Yes	Yes	3	8	9
203	R:R:F282	R:R:W336	3.01	Yes	Yes	3	8	8
204	R:R:F282	R:R:L337	6.09	Yes	No	0	8	5
205	R:R:F282	R:R:H340	9.05	Yes	No	3	8	8
206	R:R:L284	R:R:P285	3.28	No	No	0	6	9
207	R:R:L286	R:R:T289	2.95	No	No	0	7	8
208	R:R:F332	R:R:L286	3.65	Yes	No	0	9	7
209	R:R:A333	R:R:L286	3.15	No	No	0	6	7
210	R:R:F291	R:R:F292	3.22	No	No	0	4	7
211	R:R:F291	R:R:L295	6.09	No	No	0	4	3
212	R:R:V325	R:R:Y293	13.88	No	Yes	0	8	9
213	R:R:T294	R:R:T297	3.14	No	Yes	6	4	5
214	R:R:F326	R:R:T294	5.19	No	No	6	5	4
215	R:R:M296	R:R:V325	3.04	No	No	0	8	8
216	R:R:A322	R:R:T297	3.36	No	Yes	0	7	5
217	R:R:F326	R:R:T297	9.08	No	Yes	6	5	5
218	R:R:M300	R:R:R318	14.89	No	No	0	8	7
219	R:R:M300	R:R:V321	6.09	No	No	0	8	8
220	R:R:D313	R:R:K316	5.53	No	No	10	3	4
221	R:R:D313	R:R:Q317	13.05	No	No	10	3	5
222	R:R:K316	R:R:Q317	6.78	No	No	10	4	5
223	R:R:E320	R:R:K323	4.05	No	No	0	7	5
224	R:R:E320	R:R:T324	4.23	No	No	0	7	8
225	R:R:T324	R:R:V389	4.76	No	No	0	8	7
226	R:R:I381	R:R:V331	4.61	No	No	0	6	6
227	R:R:F332	R:R:W336	9.02	Yes	Yes	3	9	8
228	R:R:F332	R:R:N378	7.25	Yes	No	3	9	9
229	R:R:C335	R:R:N378	4.72	No	No	0	8	9
230	R:R:L339	R:R:W336	3.42	No	Yes	0	6	8
231	R:R:H340	R:R:W336	6.35	No	Yes	3	8	8
232	R:R:A375	R:R:W336	6.48	No	Yes	0	8	8
233	R:R:N378	R:R:W336	12.43	No	Yes	3	9	8
234	R:R:G371	R:R:L339	3.42	No	No	0	7	6
235	R:R:I372	R:R:L339	4.28	No	No	0	6	6
236	R:R:L341	R:R:L345	5.54	No	No	0	6	5
237	R:R:L364	R:R:S342	6.01	No	No	0	3	5
238	R:R:L367	R:R:S342	7.51	No	No	0	5	5
239	R:R:K346	R:R:R343	3.71	No	Yes	0	4	6
240	R:R:Q352	R:R:Y350	12.4	No	No	0	1	2
241	R:R:R357	R:R:Y350	7.2	Yes	No	0	5	2
242	R:R:D354	R:R:N351	14.81	No	No	0	1	1
243	R:R:D354	R:R:R357	3.57	No	Yes	0	1	5
244	R:R:E359	R:R:N356	17.09	No	No	0	4	3
245	R:R:S376	R:R:S379	3.26	Yes	Yes	8	7	9
246	R:R:N382	R:R:P383	4.89	No	No	0	9	9
247	R:R:L388	R:R:Y387	8.21	No	No	0	6	7
248	R:R:K394	R:R:Y387	19.11	No	No	0	8	7
249	R:R:F397	R:R:Y387	11.35	No	No	0	7	7
250	R:R:S390	R:R:V389	3.23	No	No	0	8	7
251	R:R:K394	R:R:K398	8.62	No	No	0	8	4
252	R:R:I187	R:R:I225	2.94	Yes	No	0	7	7
253	R:R:I212	R:R:K210	2.91	No	No	0	3	4
254	R:R:G186	R:R:Y281	2.9	No	Yes	0	6	6
255	R:R:D147	R:R:T188	2.89	No	No	0	9	9
256	R:R:P88	R:R:R357	2.88	No	Yes	0	7	5
257	R:R:I96	R:R:L365	2.85	Yes	No	1	5	3
258	R:R:I117	R:R:L114	2.85	No	No	0	5	5
259	R:R:I288	R:R:L284	2.85	No	No	0	7	6
260	R:R:I381	R:R:L377	2.85	No	No	0	6	6
261	R:R:I384	R:R:L388	2.85	No	No	0	7	6
262	R:R:I125	R:R:N129	2.83	Yes	No	0	7	6
263	R:R:I212	R:R:N134	2.83	No	No	0	3	8
264	R:R:L377	R:R:M374	2.83	No	No	0	6	7
265	R:R:K346	R:R:L364	2.82	No	No	0	4	3
266	R:R:H150	R:R:S379	2.79	No	Yes	0	8	9
267	R:R:L122	R:R:L386	2.77	No	No	0	9	9
268	R:R:A233	R:R:F179	2.77	No	Yes	0	7	6
269	R:R:L337	R:R:L341	2.77	No	No	0	5	6
270	R:R:L345	R:R:L349	2.77	No	No	0	5	3
271	R:R:L360	R:R:L361	2.77	No	No	0	2	3
272	R:R:L360	R:R:L364	2.77	No	No	0	2	3
273	R:R:L328	R:R:N382	2.75	No	No	0	8	9
274	R:R:D274	R:R:L347	2.71	No	No	0	5	5
275	R:R:R201	R:R:S205	2.64	No	No	0	5	7
276	R:R:F363	R:R:S362	2.64	No	No	0	3	3
277	R:R:F265	R:R:T263	2.59	No	No	0	3	3
278	R:R:V329	R:R:Y293	2.52	No	Yes	0	8	9
279	R:R:F100	R:R:I103	2.51	Yes	No	0	4	5
280	R:R:F393	R:R:I125	2.51	No	Yes	0	9	7
281	R:R:F393	R:R:I126	2.51	No	Yes	0	9	7
282	R:R:V220	R:R:W217	2.45	No	Yes	0	3	5
283	L:L:K9	R:R:Y247	2.39	No	Yes	0	0	2
284	R:R:K128	R:R:Y124	2.39	No	No	0	4	3
285	R:R:L361	R:R:Y350	2.34	No	No	0	3	2
286	R:R:L145	R:R:W226	2.28	No	No	0	6	9
287	R:R:L347	R:R:W275	2.28	No	No	0	5	5
288	R:R:F326	R:R:Y293	2.06	No	Yes	0	5	9
289	R:R:G371	R:R:P338	2.03	No	No	0	7	9
290	R:R:P88	R:R:P89	1.95	No	No	0	7	3
291	R:R:G118	R:R:T121	1.82	No	No	0	8	6
292	R:R:G115	R:R:I151	1.76	No	No	0	8	6
293	R:R:G118	R:R:I117	1.76	No	No	0	8	5
294	R:R:G213	R:R:I212	1.76	No	No	0	6	3
295	R:R:G371	R:R:M374	1.75	No	No	0	7	7
296	R:R:G239	R:R:K175	1.74	No	No	0	5	7
297	R:R:G146	R:R:L149	1.71	No	No	0	8	7
298	R:R:C298	R:R:T294	1.69	No	No	6	4	4
299	R:R:C298	R:R:T297	1.69	No	Yes	6	4	5
300	R:R:A171	R:R:I242	1.62	No	No	0	3	5
301	R:R:D354	R:R:P355	1.61	No	No	0	1	1
302	R:R:V107	R:R:V111	1.6	No	No	0	5	8
303	R:R:V223	R:R:V227	1.6	No	No	0	3	4
304	R:R:V227	R:R:V228	1.6	No	No	2	4	4
305	R:R:V321	R:R:V325	1.6	No	No	0	8	8
306	R:R:A144	R:R:L123	1.58	No	No	0	9	7
307	R:R:A385	R:R:L328	1.58	No	No	0	7	8
308	R:R:A144	R:R:N119	1.56	No	Yes	0	9	9
309	R:R:A396	R:R:N395	1.56	No	No	0	4	4
310	R:R:I116	R:R:V152	1.54	No	No	0	7	5
311	R:R:A164	R:R:D166	1.54	No	No	0	5	5
312	L:L:M7	L:L:S5	1.53	No	No	0	0	0
313	R:R:I103	R:R:T99	1.52	No	No	0	5	5
314	R:R:I344	R:R:T348	1.52	No	No	0	6	4
315	R:R:F169	R:R:G170	1.51	Yes	No	0	7	8
316	R:R:A204	R:R:E299	1.51	No	No	0	7	5
317	R:R:K97	R:R:T99	1.5	No	No	0	3	5
318	R:R:K101	R:R:T105	1.5	Yes	No	0	6	6
319	R:R:L148	R:R:S120	1.5	No	No	0	7	4
320	R:R:L224	R:R:V220	1.49	No	No	0	3	3
321	R:R:L224	R:R:V227	1.49	No	No	2	3	4
322	R:R:L224	R:R:V228	1.49	No	No	2	3	4
323	R:R:I126	R:R:I140	1.47	Yes	No	0	7	8
324	R:R:I96	R:R:K101	1.45	Yes	Yes	0	5	6
325	R:R:I209	R:R:K210	1.45	No	No	0	6	4
326	R:R:G249	R:R:Y247	1.45	No	Yes	0	3	2
327	R:R:F169	R:R:P168	1.44	Yes	No	0	7	2
328	R:R:E359	R:R:S362	1.44	No	No	0	4	3
329	L:L:L17	R:R:I94	1.43	No	No	1	0	4
330	R:R:I94	R:R:L365	1.43	No	No	1	4	3
331	R:R:E320	R:R:V321	1.43	No	No	0	7	8
332	R:R:C283	R:R:F278	1.4	No	Yes	0	5	6
333	R:R:R208	R:R:S205	1.32	No	No	0	5	7
334	R:R:F278	R:R:S279	1.32	Yes	No	0	6	4
335	R:R:R253	R:R:T244	1.29	No	No	0	5	1
336	R:R:L301	R:R:R318	1.21	No	No	0	5	7
337	R:R:I209	R:R:W206	1.17	No	No	0	6	8
338	R:R:H314	R:R:R318	1.13	No	No	0	4	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:F14	7.6525	4	0	0
2	L:L:D18	7.176	5	1	0
3	L:L:I19	6.37333	6	1	0
4	L:L:W21	13.54	6	1	0
5	R:R:I96	3.54	4	1	5
6	R:R:F100	6.48667	6	1	4
7	R:R:K101	5.6825	4	0	6
8	R:R:N119	4.605	4	0	9
9	R:R:I125	3.72	4	0	7
10	R:R:I126	3.9825	4	0	7
11	R:R:I155	4.7	4	0	7
12	R:R:W167	5.744	5	5	9
13	R:R:F169	2.9225	4	0	7
14	R:R:V177	4.076	5	1	5
15	R:R:P178	5.8325	4	1	5
16	R:R:F179	4.3325	4	0	6
17	R:R:I187	4.155	4	0	7
18	R:R:Y200	7.3475	4	0	8
19	R:R:W217	8.13	4	0	5
20	R:R:L232	5.31	4	2	5
21	R:R:P235	9.2975	4	2	8
22	R:R:E236	6.885	4	2	5
23	R:R:Y247	5.36	5	0	2
24	R:R:L252	6.535	4	0	3
25	R:R:H258	7.928	5	4	4
26	R:R:M266	5.5625	4	0	4
27	R:R:Y269	14.5875	4	2	3
28	R:R:K273	8.87	5	2	7
29	R:R:W276	9.744	5	2	4
30	R:R:F278	2.848	5	3	6
31	R:R:Y281	8.05	5	2	6
32	R:R:F282	5.346	5	3	8
33	R:R:Y293	6.816	5	0	9
34	R:R:T297	4.3175	4	6	5
35	R:R:F332	5.786	5	3	9
36	R:R:W336	6.34143	7	3	8
37	R:R:R343	10.285	4	0	6
38	R:R:R357	4.285	4	0	5
39	R:R:Y369	6.56	4	1	3
40	R:R:S376	4.33	4	8	7
41	R:R:S379	5.2675	4	8	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:D18	L:L:I19	29.9728	4.2	Yes	Yes	1	0	0
2	L:L:I19	L:L:W21	73.2478	3.52	Yes	Yes	1	0	0
3	L:L:W21	R:R:Q181	20.5495	16.43	Yes	No	1	0	6
4	R:R:P178	R:R:Q181	19.4823	3.16	Yes	No	1	5	6
5	R:R:F240	R:R:P178	20.6857	11.56	No	Yes	0	5	5
6	L:L:D18	R:R:R343	15.2816	10.72	Yes	Yes	0	0	6
7	L:L:W21	R:R:R343	27.5091	15.99	Yes	Yes	0	0	6
8	L:L:I19	R:R:N158	36.2171	7.08	Yes	No	0	0	7
9	L:L:I20	R:R:N158	25.087	8.5	No	No	0	0	7
10	R:R:D274	R:R:R343	14.6344	10.72	No	Yes	0	5	6
11	R:R:D274	R:R:K273	10.4715	6.91	No	Yes	0	5	7
12	R:R:E236	R:R:K273	12.886	5.4	Yes	Yes	2	5	7
13	R:R:E236	R:R:F240	17.469	3.5	Yes	No	0	5	5
14	L:L:C11	L:L:F14	14.9637	4.19	No	Yes	0	0	0
15	L:L:D18	L:L:F14	22.0633	10.75	Yes	Yes	0	0	0
16	L:L:I19	R:R:Y369	100	3.63	Yes	Yes	1	0	3
17	R:R:I96	R:R:Y369	72.4304	4.84	Yes	Yes	1	5	3
18	R:R:I96	R:R:L365	62.3335	2.85	Yes	No	1	5	3
19	L:L:L17	R:R:L365	45.7198	6.92	No	No	1	0	3
20	L:L:L17	L:L:Y13	43.9903	5.86	No	No	0	0	0
21	L:L:Y13	R:R:Y247	41.6705	11.91	No	Yes	0	0	2
22	R:R:L252	R:R:Y247	32.058	4.69	Yes	Yes	0	3	2
23	R:R:L252	R:R:M245	14.8653	8.48	Yes	No	0	3	1
24	R:R:I243	R:R:M245	12.4016	10.2	No	No	0	1	1
25	R:R:I254	R:R:L252	12.3751	9.99	No	Yes	0	4	3
26	L:L:F14	R:R:K346	11.7015	8.69	Yes	No	0	0	4
27	R:R:K346	R:R:L364	32.0088	2.82	No	No	0	4	3
28	R:R:L360	R:R:L364	25.7304	2.77	No	No	0	2	3
29	R:R:L360	R:R:L361	23.6225	2.77	No	No	0	2	3
30	R:R:L361	R:R:Y350	21.507	2.34	No	No	0	3	2
31	R:R:R357	R:R:Y350	17.2533	7.2	Yes	No	0	5	2
32	R:R:K346	R:R:R343	31.6606	3.71	No	Yes	0	4	6
33	L:L:I19	R:R:I372	47.4266	4.42	Yes	No	0	0	6
34	L:L:I20	R:R:V177	19.9402	3.07	No	Yes	1	0	5
35	L:L:W21	R:R:L277	31.2595	11.39	Yes	No	0	0	6
36	R:R:I94	R:R:L365	14.2787	1.43	No	No	1	4	3
37	R:R:C358	R:R:I94	12.4849	3.27	No	No	0	8	4
38	R:R:I96	R:R:K101	10.0023	1.45	Yes	Yes	0	5	6
39	R:R:F100	R:R:Y369	23.3576	7.22	Yes	Yes	1	4	3
40	R:R:D154	R:R:N158	36.6334	12.12	No	No	0	6	7
41	R:R:D154	R:R:I155	62.9958	7	No	Yes	0	6	7
42	R:R:I155	R:R:S376	52.2328	4.64	Yes	Yes	0	7	7
43	R:R:D154	R:R:I372	32.1299	8.4	No	No	0	6	6
44	R:R:I151	R:R:S376	17.8701	6.19	No	Yes	8	6	7
45	R:R:G115	R:R:I151	16.239	1.76	No	No	0	8	6
46	R:R:C380	R:R:G115	14.5058	3.92	No	No	0	8	8
47	R:R:C380	R:R:L114	12.8368	4.76	No	No	0	8	5
48	R:R:S376	R:R:S379	29.0342	3.26	Yes	Yes	8	7	9
49	R:R:D147	R:R:S379	24.4399	8.83	No	Yes	0	9	9
50	R:R:D147	R:R:N119	22.1692	6.73	No	Yes	0	9	9
51	L:L:W21	R:R:V185	65.0015	4.9	Yes	No	0	0	7
52	R:R:V185	R:R:W336	62.6438	3.68	No	Yes	0	7	8
53	R:R:F332	R:R:W336	65.7773	9.02	Yes	Yes	3	9	8
54	R:R:F332	R:R:L192	29.7419	3.65	Yes	No	0	9	8
55	R:R:L143	R:R:L192	28.6331	5.54	No	No	0	9	8
56	R:R:L143	R:R:N382	26.5819	5.49	No	No	0	9	9
57	R:R:N382	R:R:P383	23.6982	4.89	No	No	0	9	9
58	R:R:I372	R:R:L339	32.9133	4.28	No	No	0	6	6
59	R:R:L339	R:R:W336	31.6152	3.42	No	Yes	0	6	8
60	R:R:N119	R:R:P383	19.4823	3.26	Yes	No	0	9	9
61	R:R:L122	R:R:P383	33.7193	4.93	No	No	0	9	9
62	R:R:F397	R:R:L122	30.8621	4.87	No	No	0	7	9
63	R:R:F397	R:R:T121	22.0368	7.78	No	No	0	7	6
64	R:R:I125	R:R:T121	28.0957	3.04	Yes	No	0	7	6
65	R:R:I117	R:R:L114	11.5312	2.85	No	No	0	5	5
66	R:R:G118	R:R:I117	10.7024	1.76	No	No	0	8	5
67	R:R:G118	R:R:T121	10.271	1.82	No	No	0	8	6
68	R:R:F393	R:R:I125	14.8388	2.51	No	Yes	0	9	7
69	R:R:F393	R:R:I126	13.1169	2.51	No	Yes	0	9	7
70	R:R:K273	R:R:W276	20.4889	10.44	Yes	Yes	2	7	4
71	R:R:L232	R:R:W276	44.7661	7.97	Yes	Yes	2	5	4
72	R:R:L232	R:R:V228	57.2964	2.98	Yes	No	2	5	4
73	R:R:L224	R:R:V228	48.9782	1.49	No	No	2	3	4
74	R:R:L224	R:R:V220	47.2109	1.49	No	No	0	3	3
75	R:R:V220	R:R:W217	44.8683	2.45	No	Yes	0	3	5
76	R:R:R201	R:R:W217	38.5218	12	No	Yes	0	5	5
77	R:R:D198	R:R:R201	33.2766	3.57	No	No	0	8	5
78	R:R:D198	R:R:P136	35.8348	4.83	No	No	0	8	8
79	R:R:N134	R:R:P136	21.6621	8.15	No	No	0	8	8
80	R:R:N134	R:R:N137	10.271	4.09	No	No	0	8	8
81	R:R:G135	R:R:P136	16.8521	4.06	No	No	0	7	8
82	R:R:G135	R:R:P215	14.7517	4.06	No	No	0	7	1
83	R:R:P215	R:R:V214	10.5283	3.53	No	No	0	1	6
84	R:R:F332	R:R:L286	50.14	3.65	Yes	No	0	9	7
85	R:R:L286	R:R:T289	48.1873	2.95	No	No	0	7	8
86	R:R:S196	R:R:T289	47.226	6.4	No	No	0	9	8
87	R:R:S196	R:R:Y293	41.5948	6.36	No	Yes	0	9	9
88	R:R:R199	R:R:Y293	12.7914	9.26	No	Yes	0	9	9
89	R:R:L195	R:R:R199	11.7545	14.58	No	No	0	9	9
90	R:R:L139	R:R:L195	10.937	4.15	No	No	0	7	9
91	R:R:D198	R:R:L139	10.4715	8.14	No	No	0	8	7
92	R:R:I153	R:R:V177	23.7019	4.61	No	Yes	0	5	5
93	R:R:I153	R:R:I180	22.4493	8.83	No	No	0	5	5
94	R:R:F179	R:R:I180	19.9213	3.77	Yes	No	0	6	5
95	R:R:F179	R:R:V230	16.0725	5.24	Yes	No	0	6	3
96	R:R:S229	R:R:V230	14.7744	4.85	No	No	0	8	3
97	R:R:I187	R:R:S229	12.1556	3.1	Yes	No	0	7	8
98	R:R:I157	R:R:V177	11.6485	4.61	No	Yes	0	6	5
99	R:R:M173	R:R:V177	15.6676	4.56	No	Yes	0	6	5
100	R:R:F169	R:R:M173	14.4301	3.73	Yes	No	0	7	6
101	R:R:F169	R:R:P168	12.1556	1.44	Yes	No	0	7	2
102	R:R:P168	R:R:Y160	10.8348	4.17	No	No	0	2	4
103	R:R:I157	R:R:W167	10.411	4.7	No	Yes	0	6	9
104	R:R:V185	R:R:Y281	31.9331	6.31	No	Yes	0	7	6
105	R:R:L277	R:R:Y281	18.3205	5.86	No	Yes	0	6	6
106	R:R:V325	R:R:Y293	28.8185	13.88	No	Yes	0	8	9
107	R:R:M296	R:R:V325	14.256	3.04	No	No	0	8	8
108	R:R:M296	R:R:Y200	11.5615	3.59	No	Yes	0	8	8
109	R:R:I212	R:R:N134	12.6892	2.83	No	No	0	3	8
110	R:R:F280	R:R:Y281	20.0802	16.5	No	Yes	2	5	6
111	R:R:M266	R:R:P235	13.484	3.35	Yes	Yes	0	4	8
112	R:R:F282	R:R:W336	10.744	3.01	Yes	Yes	3	8	8
113	R:R:V321	R:R:V325	14.1008	1.6	No	No	0	8	8
114	R:R:G371	R:R:L339	10.0325	3.42	No	No	0	7	6
115	R:R:P178	R:R:V177	29.2991	3.53	Yes	Yes	1	5	5
116	R:R:K273	R:R:L277	14.3203	8.46	Yes	No	0	7	6
117	R:R:W276	R:R:Y269	12.9466	10.61	Yes	Yes	2	4	3
118	R:R:W276	R:R:Y281	25.0719	8.68	Yes	Yes	2	4	6
119	R:R:F280	R:R:L232	18.3924	7.31	No	Yes	2	5	5

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:S2	R:R:L257	6.01	0	No	No	0	5	0	1
L:L:S2	R:R:K270	6.12	0	No	No	0	4	0	1
L:L:L6	R:R:H258	3.86	4	No	Yes	0	4	0	1
L:L:L6	R:R:P259	4.93	4	No	No	0	6	0	1
L:L:L6	R:R:V260	2.98	4	No	No	0	3	0	1
L:L:E10	R:R:R357	3.49	0	No	Yes	0	5	0	1
L:L:V12	R:R:L252	2.98	0	No	Yes	0	3	0	1
L:L:Y13	R:R:Y247	11.91	0	No	Yes	0	2	0	1
L:L:F14	R:R:K346	8.69	0	Yes	No	0	4	0	1
L:L:H16	R:R:I254	5.3	0	No	No	0	4	0	1
L:L:L17	R:R:L365	6.92	1	No	No	0	3	0	1
L:L:D18	R:R:R343	10.72	1	Yes	Yes	0	6	0	1
L:L:D18	R:R:D368	3.99	1	Yes	No	0	4	0	1
L:L:I19	R:R:N158	7.08	1	Yes	No	0	7	0	1
L:L:I19	R:R:D368	15.39	1	Yes	No	0	4	0	1
L:L:I19	R:R:Y369	3.63	1	Yes	Yes	0	3	0	1
L:L:I19	R:R:I372	4.42	1	Yes	No	0	6	0	1
L:L:I20	R:R:N158	8.5	1	No	No	0	7	0	1
L:L:I20	R:R:V177	3.07	1	No	Yes	0	5	0	1
L:L:I20	R:R:P178	5.08	1	No	Yes	0	5	0	1
L:L:W21	R:R:Q181	16.43	1	Yes	No	0	6	0	1
L:L:W21	R:R:K182	29.01	1	Yes	No	0	4	0	1
L:L:W21	R:R:V185	4.9	1	Yes	No	0	7	0	1
L:L:W21	R:R:L277	11.39	1	Yes	No	0	6	0	1
L:L:W21	R:R:R343	15.99	1	Yes	Yes	0	6	0	1
R:R:C358	R:R:I94	3.27	0	No	No	8	4	2	1
R:R:F100	R:R:I96	5.02	1	Yes	Yes	4	5	2	2
R:R:I96	R:R:Y369	4.84	1	Yes	Yes	5	3	2	1
R:R:F100	R:R:Y369	7.22	1	Yes	Yes	4	3	2	1
R:R:I153	R:R:V177	4.61	0	No	Yes	5	5	2	1
R:R:D154	R:R:N158	12.12	0	No	No	6	7	2	1
R:R:D154	R:R:I372	8.4	0	No	No	6	6	2	1
R:R:I157	R:R:V177	4.61	0	No	Yes	6	5	2	1
R:R:L162	R:R:Y369	10.55	0	No	Yes	4	3	2	1
R:R:M173	R:R:V177	4.56	0	No	Yes	6	5	2	1
R:R:P178	R:R:V177	3.53	1	Yes	Yes	5	5	1	1
R:R:P178	R:R:Q181	3.16	1	Yes	No	5	6	1	1
R:R:F240	R:R:P178	11.56	0	No	Yes	5	5	2	1
R:R:K182	R:R:Q181	10.85	1	No	No	4	6	1	1
R:R:V185	R:R:Y281	6.31	0	No	Yes	7	6	1	2
R:R:V185	R:R:W336	3.68	0	No	Yes	7	8	1	2
R:R:F240	R:R:L257	17.05	0	No	No	5	5	2	1
R:R:D241	R:R:H258	17.65	0	No	Yes	4	4	2	1
R:R:I243	R:R:M245	10.2	0	No	No	1	1	2	2
R:R:H258	R:R:I243	6.63	4	Yes	No	4	1	1	2
R:R:L252	R:R:M245	8.48	0	Yes	No	3	1	1	2
R:R:S250	R:R:Y247	6.36	0	No	Yes	1	2	2	1
R:R:L252	R:R:Y247	4.69	0	Yes	Yes	3	2	1	1
R:R:I254	R:R:L252	9.99	0	No	Yes	4	3	1	1
R:R:I254	R:R:L256	5.71	0	No	No	4	4	1	2
R:R:L256	R:R:P259	4.93	0	No	No	4	6	2	1
R:R:H258	R:R:P259	4.58	4	Yes	No	4	6	1	1
R:R:H258	R:R:V260	6.92	4	Yes	No	4	3	1	1
R:R:D274	R:R:K273	6.91	0	No	Yes	5	7	2	2
R:R:K273	R:R:L277	8.46	2	Yes	No	7	6	2	1
R:R:D274	R:R:R343	10.72	0	No	Yes	5	6	2	1
R:R:L277	R:R:Y281	5.86	0	No	Yes	6	6	1	2
R:R:L339	R:R:W336	3.42	0	No	Yes	6	8	2	2
R:R:I372	R:R:L339	4.28	0	No	No	6	6	1	2
R:R:K346	R:R:R343	3.71	0	No	Yes	4	6	1	1
R:R:R357	R:R:Y350	7.2	0	Yes	No	5	2	1	2
R:R:D354	R:R:R357	3.57	0	No	Yes	1	5	2	1
R:R:P88	R:R:R357	2.88	0	No	Yes	7	5	2	1
R:R:I96	R:R:L365	2.85	1	Yes	No	5	3	2	1
R:R:K346	R:R:L364	2.82	0	No	No	4	3	1	2
L:L:K9	R:R:Y247	2.39	0	No	Yes	0	2	0	1
R:R:G249	R:R:Y247	1.45	0	No	Yes	3	2	2	1
L:L:L17	R:R:I94	1.43	1	No	No	0	4	0	1
R:R:I94	R:R:L365	1.43	1	No	No	4	3	1	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	8XWQ_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	2.95
Number of Linked Nodes	299
Number of Links	338
Number of Hubs	41
Number of Links mediated by Hubs	156
Number of Communities	10
Number of Nodes involved in Communities	59
Number of Links involved in Communities	75

Path Summary
Number Of Nodes in MetaPath	120
Number Of Links MetaPath	119
Number of Shortest Paths	77741
Length Of Smallest Path	3
Average Path Length	14.0613
Length of Longest Path	30
Minimum Path Strength	1.17
Average Path Strength	5.72627
Maximum Path Strength	22.5
Minimum Path Correlation	0.7
Average Path Correlation	0.92803
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	3.84615
Average % Of Corr. Nodes	47.0911
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	39.8486
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain • Ras-like P-loop GTPases • G protein-coupled receptor-like
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain • Ras-like P-loop GTPases • G protein-coupled receptor-like
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P24530
Sequence	>8XWQ_nogp_Chain_R P P C Q G P I E I K E T F K Y I N T V V S C L V F V L G I I G N S T L L Y I I Y K N K C M R N G P N I L I A S L A L G D L L H I V I D I P I N V Y K L L A E D W P F G A E M C K L V P F I Q K A S V G I T V L S L C A L S I D R Y R A V A S W S R I K G I G V P K W T A V E I V L I W V V S V V L A V P E A I G F D I I T M D Y K G S Y L R I C L L H P V Q K T A F M Q F Y K T A K D W W L F S F Y F C L P L A I T A F F Y T L M T C E M L N D H L K Q R R E V A K T V F C L V L V F A L C W L P L H L S R I L K L T L Y N Q N D P N R C E L L S F L L V L D Y I G I N M A S L N S C I N P I A L Y L V S K R F K N A F K S Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	6LRY	A	Peptide	Endothelin	ET_B	Homo sapiens	Sarafotoxin-B	-	-	3	2020-02-12	doi.org/10.1016/j.bbrc.2019.12.091
	5GLH	A	Peptide	Endothelin	ET_B	Homo sapiens	Endothelin-1	-	-	2.8	2016-09-07	doi.org/10.1038/nature19319
	5GLI	A	Peptide	Endothelin	ET_B	Homo sapiens	-	-	-	2.5	2016-09-07	doi.org/10.1038/nature19319
	5X93	A	Peptide	Endothelin	ET_B	Homo sapiens	K-8794	-	-	2.2	2017-08-16	doi.org/10.1038/nsmb.3450
	5XPR	A	Peptide	Endothelin	ET_B	Homo sapiens	Bosentan	-	-	3.6	2017-08-16	doi.org/10.1038/nsmb.3450
	6IGK	A	Peptide	Endothelin	ET_B	Homo sapiens	Endothelin-3	-	-	2	2018-11-21	doi.org/10.1038/s41467-018-07094-0
	6IGL	A	Peptide	Endothelin	ET_B	Homo sapiens	IRL1620	-	-	2.7	2018-11-21	doi.org/10.1038/s41467-018-07094-0
	8HBD	A	Peptide	Endothelin	ET_B	Homo sapiens	IRL1620	-	Gi1/β1/γ2	2.99	2023-03-22	doi.org/10.1038/s41467-023-36998-9
	8HBD (No Gprot)	A	Peptide	Endothelin	ET_B	Homo sapiens	IRL1620	-		2.99	2023-03-22	doi.org/10.1038/s41467-023-36998-9
	8HCX	A	Peptide	Endothelin	ET_B	Homo sapiens	Endothelin-1	-	chim(NtGi2L-Gs-CtGq)/β1/γ2	3.5	2023-03-22	doi.org/10.1038/s41467-023-36998-9
	8HCX (No Gprot)	A	Peptide	Endothelin	ET_B	Homo sapiens	Endothelin-1	-		3.5	2023-03-22	doi.org/10.1038/s41467-023-36998-9
	6K1Q	A	Peptide	Endothelin	ET_B	Homo sapiens	IRL2500	-	-	2.7	2019-07-17	doi.org/10.1038/s42003-019-0482-7
	8IY5	A	Peptide	Endothelin	ET_B	Homo sapiens	Endothelin-1	-	Gi1/β1/γ2	2.8	2023-08-16	doi.org/10.7554/eLife.85821
	8IY5 (No Gprot)	A	Peptide	Endothelin	ET_B	Homo sapiens	Endothelin-1	-		2.8	2023-08-16	doi.org/10.7554/eLife.85821
	8IY6	A	Peptide	Endothelin	ET_B	Homo sapiens	Endothelin-1	-	-	3.13	2023-08-16	doi.org/10.7554/eLife.85821
	8XVE	A	Peptide	Endothelin	ET_B	Homo sapiens	BQ3020	-	chim(Gs-CtGq)/β1/γ2	3	2024-08-28	doi.org/10.1038/s41421-024-00705-9
	8XVE (No Gprot)	A	Peptide	Endothelin	ET_B	Homo sapiens	BQ3020	-		3	2024-08-28	doi.org/10.1038/s41421-024-00705-9
	8XVH	A	Peptide	Endothelin	ET_B	Homo sapiens	Endothelin-1	-	chim(Gs-CtGq)/β1/γ2	3.26	2024-08-28	doi.org/10.1038/s41421-024-00705-9
	8XVH (No Gprot)	A	Peptide	Endothelin	ET_B	Homo sapiens	Endothelin-1	-		3.26	2024-08-28	doi.org/10.1038/s41421-024-00705-9
	9KDF	A	Peptide	Endothelin	ET_B	Homo sapiens	RES-701-3	-	-	3.3	2025-05-07	doi.org/10.1038/s41467-025-57960-x
	9KDG	A	Peptide	Endothelin	ET_B	Homo sapiens	-	-	-	3.33	2025-05-07	doi.org/10.1038/s41467-025-57960-x
	8XWP	A	Peptide	Endothelin	ET_B	Homo sapiens	Endothelin-1	-	Gi1/β1/γ2	3.21	2024-10-02	doi.org/10.1038/s42003-024-06905-z
	8XWP (No Gprot)	A	Peptide	Endothelin	ET_B	Homo sapiens	Endothelin-1	-		3.21	2024-10-02	doi.org/10.1038/s42003-024-06905-z
	8XWQ	A	Peptide	Endothelin	ET_B	Homo sapiens	Endothelin-1	-	Gi1/β1/γ2	4.6	2024-10-02	doi.org/10.1038/s42003-024-06905-z
	8XWQ (No Gprot)	A	Peptide	Endothelin	ET_B	Homo sapiens	Endothelin-1	-		4.6	2024-10-02	doi.org/10.1038/s42003-024-06905-z
	8ZRT	A	Peptide	Endothelin	ET_B	Homo sapiens	ET-1	-	-	3.62	2024-10-02	doi.org/10.1038/s42003-024-06905-z

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 8XWQ_nogp.zip

You can click to copy the link of this page to easily come back here later

or use this QR code to link and share this page.

You can also read or download a guide explaining the meaning of all files and numerical data.