psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:C48	R:R:Y51	4.03	No	No	0	5	5
2	R:R:C48	R:R:F309	2.79	No	No	0	5	4
3	R:R:I313	R:R:I50	7.36	No	No	0	4	5
4	R:R:Y108	R:R:Y51	10.92	Yes	No	0	5	5
5	R:R:I58	R:R:Y54	4.84	No	No	2	7	7
6	R:R:D104	R:R:Y54	16.09	No	No	2	6	7
7	R:R:F320	R:R:Y54	6.19	Yes	No	2	7	7
8	R:R:I58	R:R:I62	2.94	No	No	0	7	6
9	R:R:F320	R:R:I58	5.02	Yes	No	2	7	7
10	R:R:C324	R:R:G61	3.92	No	No	0	7	8
11	R:R:I62	R:R:L97	5.71	No	Yes	0	6	6
12	R:R:I67	R:R:L63	4.28	Yes	No	0	7	4
13	R:R:L345	R:R:L63	4.15	No	No	0	6	4
14	R:R:F341	R:R:G64	3.01	No	No	0	6	8
15	R:R:A90	R:R:N65	3.13	No	Yes	0	9	9
16	R:R:D93	R:R:N65	8.08	Yes	Yes	0	9	9
17	R:R:L94	R:R:N65	6.87	No	Yes	0	7	9
18	R:R:N65	R:R:P327	6.52	Yes	No	0	9	9
19	R:R:F341	R:R:I67	18.84	No	Yes	0	6	7
20	R:R:I67	R:R:Q344	2.74	Yes	No	0	7	5
21	R:R:I86	R:R:L68	4.28	No	Yes	0	8	9
22	R:R:A90	R:R:L68	4.73	No	Yes	0	9	9
23	R:R:L68	R:R:P327	3.28	Yes	No	0	9	9
24	R:R:F337	R:R:L68	4.87	Yes	Yes	0	9	9
25	R:R:I69	R:R:K70	4.36	Yes	No	0	7	4
26	R:R:I69	R:R:T87	3.04	Yes	No	5	7	6
27	R:R:F91	R:R:I69	7.54	No	Yes	5	6	7
28	R:R:I69	R:R:L94	2.85	Yes	No	0	7	7
29	R:R:T75	R:R:V71	3.17	Yes	Yes	3	5	7
30	R:R:M78	R:R:V71	3.04	Yes	Yes	3	7	7
31	R:R:H340	R:R:V71	6.92	Yes	Yes	3	5	7
32	R:R:Q344	R:R:V71	4.3	No	Yes	0	5	7
33	R:R:F72	R:R:F73	6.43	No	No	0	7	4
34	R:R:F72	R:R:T87	22.05	No	No	0	7	6
35	R:R:F73	R:R:F91	4.29	No	No	0	4	6
36	R:R:K74	R:R:Q344	6.78	No	No	0	5	5
37	R:R:S77	R:R:T75	3.2	No	Yes	3	6	5
38	R:R:M78	R:R:T75	6.02	Yes	Yes	3	7	5
39	R:R:H340	R:R:T75	12.32	Yes	Yes	3	5	5
40	R:R:K76	R:R:Q79	5.42	No	No	0	6	7
41	R:R:M78	R:R:S77	3.07	Yes	No	3	7	6
42	R:R:H340	R:R:S77	2.79	Yes	No	3	5	6
43	R:R:M78	R:R:N83	4.21	Yes	No	0	7	8
44	R:R:F337	R:R:M78	3.73	Yes	Yes	0	9	7
45	R:R:H340	R:R:M78	5.25	Yes	Yes	3	5	7
46	R:R:P82	R:R:T80	10.49	No	No	0	8	8
47	R:R:N83	R:R:T80	7.31	No	No	0	8	8
48	R:R:P82	R:R:V81	3.53	No	No	0	8	6
49	R:R:N159	R:R:V81	10.35	Yes	No	1	6	6
50	R:R:T164	R:R:V81	6.35	Yes	No	1	7	6
51	R:R:F85	R:R:I84	3.77	Yes	No	1	8	5
52	R:R:I84	R:R:T164	6.08	No	Yes	1	5	7
53	R:R:F85	R:R:I140	5.02	Yes	No	1	8	6
54	R:R:F85	R:R:L141	3.65	Yes	No	1	8	9
55	R:R:D144	R:R:F85	5.97	No	Yes	1	8	8
56	R:R:F85	R:R:T164	5.19	Yes	Yes	1	8	7
57	R:R:I86	R:R:L330	4.28	No	No	0	8	9
58	R:R:F91	R:R:T87	5.19	No	No	5	6	6
59	R:R:S88	R:R:T137	4.8	No	No	0	9	7
60	R:R:S88	R:R:W172	6.18	No	No	0	9	9
61	R:R:D93	R:R:L89	9.5	Yes	Yes	1	9	9
62	R:R:L89	R:R:S134	3	Yes	No	1	9	9
63	R:R:L89	R:R:T137	5.9	Yes	No	1	9	7
64	R:R:L138	R:R:L89	6.92	No	Yes	1	8	9
65	R:R:L141	R:R:L89	2.77	No	Yes	1	9	9
66	R:R:L89	R:R:N326	9.61	Yes	Yes	1	9	9
67	R:R:D93	R:R:S134	2.94	Yes	No	1	9	9
68	R:R:D93	R:R:S323	10.31	Yes	No	0	9	9
69	R:R:D93	R:R:N326	6.73	Yes	Yes	1	9	9
70	R:R:L95	R:R:S130	3	No	No	0	6	8
71	R:R:C100	R:R:L96	3.17	No	Yes	0	6	7
72	R:R:L96	R:R:S130	4.5	Yes	No	0	7	8
73	R:R:L96	R:R:V131	4.47	Yes	No	0	7	8
74	R:R:L96	R:R:S323	4.5	Yes	No	0	7	9
75	R:R:F320	R:R:L97	3.65	Yes	Yes	0	7	6
76	R:R:L97	R:R:S323	6.01	Yes	No	0	6	9
77	R:R:L123	R:R:T99	2.95	No	No	0	5	6
78	R:R:I126	R:R:T99	7.6	No	No	0	5	6
79	R:R:R127	R:R:T99	5.17	No	No	0	6	6
80	R:R:C100	R:R:R127	2.79	No	No	0	6	6
81	R:R:C100	R:R:F320	6.98	No	Yes	0	6	7
82	R:R:P102	R:R:V101	3.53	No	No	0	8	7
83	R:R:L123	R:R:P102	4.93	No	No	0	5	8
84	R:R:L123	R:R:V103	5.96	No	No	0	5	5
85	R:R:D104	R:R:Y108	8.05	No	Yes	2	6	5
86	R:R:D104	R:R:R316	5.96	No	Yes	2	6	5
87	R:R:F115	R:R:T106	14.27	No	No	0	6	5
88	R:R:H107	R:R:Y108	8.71	No	Yes	0	5	5
89	R:R:F309	R:R:Y108	9.28	No	Yes	0	4	5
90	R:R:I313	R:R:Y108	3.63	No	Yes	0	4	5
91	R:R:R316	R:R:Y108	4.12	Yes	Yes	2	5	5
92	R:R:A110	R:R:F115	2.77	No	No	0	4	6
93	R:R:C120	R:R:L114	6.35	No	No	0	9	3
94	R:R:F125	R:R:T129	6.49	No	Yes	6	6	5
95	R:R:A179	R:R:F125	4.16	No	No	6	7	6
96	R:R:A179	R:R:L128	4.73	No	No	0	7	5
97	R:R:E182	R:R:L128	6.63	No	No	0	5	5
98	R:R:S175	R:R:T129	4.8	Yes	Yes	0	8	5
99	R:R:M176	R:R:T129	4.52	No	Yes	0	4	5
100	R:R:A179	R:R:T129	3.36	No	Yes	6	7	5
101	R:R:V131	R:R:W284	7.36	No	Yes	0	8	8
102	R:R:G132	R:R:S175	3.71	No	Yes	0	7	8
103	R:R:F225	R:R:G132	3.01	No	No	0	6	7
104	R:R:V133	R:R:W172	17.16	No	No	0	7	9
105	R:R:S175	R:R:V133	6.46	Yes	No	0	8	7
106	R:R:L138	R:R:S134	3	No	No	1	8	9
107	R:R:F225	R:R:V135	5.24	No	No	0	6	8
108	R:R:P229	R:R:V135	3.53	No	No	0	9	8
109	R:R:F136	R:R:V171	6.55	No	No	0	6	7
110	R:R:L141	R:R:T137	2.95	No	No	1	9	7
111	R:R:L138	R:R:N326	8.24	No	Yes	1	8	9
112	R:R:I232	R:R:T139	7.6	No	No	0	6	7
113	R:R:I233	R:R:T139	4.56	No	No	0	8	7
114	R:R:D144	R:R:I140	4.2	No	No	1	8	6
115	R:R:I140	R:R:K167	7.27	No	No	0	6	6
116	R:R:I233	R:R:S142	9.29	No	No	7	8	9
117	R:R:S142	R:R:Y236	6.36	No	Yes	0	9	7
118	R:R:S142	R:R:Y237	12.72	No	Yes	7	9	9
119	R:R:R145	R:R:Y237	3.09	No	Yes	0	9	9
120	R:R:V150	R:R:Y146	13.88	No	No	0	7	8
121	R:R:L239	R:R:Y146	8.21	No	No	0	5	8
122	R:R:E154	R:R:K147	5.4	No	No	0	4	5
123	R:R:I240	R:R:V149	4.61	No	No	8	8	9
124	R:R:L244	R:R:V149	2.98	Yes	No	8	8	9
125	R:R:K151	R:R:V150	3.04	No	No	0	6	7
126	R:R:T243	R:R:V150	6.35	No	No	0	6	7
127	R:R:E154	R:R:K151	4.05	No	No	0	4	6
128	R:R:N159	R:R:Q156	6.6	Yes	No	0	6	4
129	R:R:N159	R:R:T164	4.39	Yes	Yes	1	6	7
130	R:R:I177	R:R:L180	4.28	No	No	0	4	4
131	R:R:L212	R:R:Q299	11.98	No	No	0	1	1
132	R:R:H217	R:R:L213	15.43	No	No	0	6	4
133	R:R:E215	R:R:L219	3.98	No	Yes	4	3	5
134	R:R:E215	R:R:S295	11.5	No	No	4	3	4
135	R:R:I216	R:R:S295	3.1	No	No	0	5	4
136	R:R:L219	R:R:S218	3	Yes	No	4	5	5
137	R:R:F222	R:R:S218	9.25	No	No	4	6	5
138	R:R:F222	R:R:L219	3.65	No	Yes	4	6	5
139	R:R:L219	R:R:Y291	22.27	Yes	No	0	5	6
140	R:R:L219	R:R:S295	3	Yes	No	4	5	4
141	R:R:F222	R:R:F225	3.22	No	No	0	6	6
142	R:R:I227	R:R:L223	2.85	No	No	0	4	5
143	R:R:L223	R:R:L292	5.54	No	No	0	5	5
144	R:R:I227	R:R:Y226	4.84	No	Yes	0	4	8
145	R:R:L230	R:R:Y226	3.52	No	Yes	0	6	8
146	R:R:W284	R:R:Y226	3.86	Yes	Yes	1	8	8
147	R:R:L285	R:R:Y226	7.03	No	Yes	0	6	8
148	R:R:H288	R:R:Y226	16.33	No	Yes	1	7	8
149	R:R:I228	R:R:P229	3.39	No	No	0	5	9
150	R:R:F280	R:R:L230	3.65	No	No	0	9	6
151	R:R:A281	R:R:L230	3.15	No	No	0	5	6
152	R:R:I232	R:R:Y236	14.51	No	Yes	0	6	7
153	R:R:I233	R:R:Y237	7.25	No	Yes	7	8	9
154	R:R:S234	R:R:V277	3.23	No	No	0	4	8
155	R:R:V235	R:R:Y236	3.79	No	Yes	0	4	7
156	R:R:L239	R:R:V235	2.98	No	No	0	5	4
157	R:R:V273	R:R:Y237	7.57	No	Yes	0	8	9
158	R:R:L239	R:R:R242	4.86	No	No	0	5	4
159	R:R:I240	R:R:L244	2.85	No	Yes	8	8	8
160	R:R:I240	R:R:V273	3.07	No	No	0	8	8
161	R:R:L244	R:R:R266	3.64	Yes	No	0	8	7
162	R:R:I269	R:R:L244	4.28	No	Yes	0	7	8
163	R:R:A270	R:R:L244	4.73	No	Yes	0	7	8
164	R:R:K267	R:R:Y245	3.58	Yes	No	0	5	5
165	R:R:A270	R:R:Y245	6.67	No	No	0	7	5
166	R:R:N250	R:R:S247	2.98	No	No	0	3	7
167	R:R:R266	R:R:S247	10.54	No	No	0	7	7
168	R:R:L249	R:R:T248	2.95	No	No	0	4	4
169	R:R:I263	R:R:T248	3.04	Yes	No	0	3	4
170	R:R:I251	R:R:N250	2.83	Yes	No	0	4	3
171	R:R:I251	R:R:P252	5.08	Yes	No	0	4	4
172	R:R:A259	R:R:I251	3.25	No	Yes	0	3	4
173	R:R:I251	R:R:Q262	2.74	Yes	No	0	4	4
174	R:R:I251	R:R:I263	2.94	Yes	Yes	0	4	3
175	R:R:E254	R:R:P252	6.29	No	No	0	4	4
176	R:R:I263	R:R:T253	3.04	Yes	No	0	3	4
177	R:R:E254	R:R:Q256	5.1	No	No	0	4	1
178	R:R:H258	R:R:S257	4.18	No	No	0	4	2
179	R:R:Q262	R:R:R266	5.84	No	No	0	4	7
180	R:R:I263	R:R:K267	2.91	Yes	Yes	0	3	5
181	R:R:R268	R:R:S265	3.95	No	No	0	7	6
182	R:R:R268	R:R:W332	6	No	No	0	7	6
183	R:R:I269	R:R:V273	3.07	No	No	0	7	8
184	R:R:I269	R:R:L333	7.14	No	No	0	7	6
185	R:R:T272	R:R:W332	12.13	No	No	0	8	6
186	R:R:L333	R:R:T272	7.37	No	No	0	6	8
187	R:R:L279	R:R:V275	2.98	No	No	0	7	6
188	R:R:A329	R:R:L276	4.73	No	No	0	8	8
189	R:R:L279	R:R:V325	2.98	No	No	0	7	6
190	R:R:F280	R:R:W284	7.02	No	Yes	1	9	8
191	R:R:F280	R:R:N322	7.25	No	Yes	1	9	9
192	R:R:C283	R:R:S321	5.16	No	No	0	8	5
193	R:R:H288	R:R:W284	4.23	No	Yes	1	7	8
194	R:R:N322	R:R:W284	6.78	Yes	Yes	1	9	8
195	R:R:L285	R:R:P286	3.28	No	No	0	6	9
196	R:R:L285	R:R:L289	8.3	No	No	0	6	6
197	R:R:P286	R:R:S315	3.56	No	No	0	9	6
198	R:R:L318	R:R:P286	3.28	No	No	0	7	9
199	R:R:H288	R:R:N287	3.83	No	No	0	7	7
200	R:R:N287	R:R:S315	4.47	No	No	0	7	6
201	R:R:H294	R:R:L290	10.29	Yes	Yes	0	4	4
202	R:R:F311	R:R:L290	12.18	No	Yes	0	5	4
203	R:R:L290	R:R:T312	2.95	Yes	No	0	4	4
204	R:R:L290	R:R:S315	4.5	Yes	No	0	4	6
205	R:R:H294	R:R:Y293	6.53	Yes	No	0	4	5
206	R:R:T297	R:R:Y293	9.99	No	No	0	4	5
207	R:R:H294	R:R:Y301	8.71	Yes	No	0	4	2
208	R:R:H294	R:R:H308	7.17	Yes	No	0	4	3
209	R:R:S298	R:R:T297	3.2	No	No	0	4	4
210	R:R:D303	R:R:V302	5.84	No	No	0	2	1
211	R:R:H308	R:R:T312	4.11	No	No	0	3	4
212	R:R:F314	R:R:I310	5.02	No	No	0	5	1
213	R:R:R316	R:R:T312	3.88	Yes	No	0	5	4
214	R:R:F320	R:R:R316	5.34	Yes	Yes	2	7	5
215	R:R:N322	R:R:N326	9.54	Yes	Yes	1	9	9
216	R:R:C324	R:R:F328	4.19	No	No	0	7	7
217	R:R:N326	R:R:P327	3.26	Yes	No	0	9	9
218	R:R:F337	R:R:L330	13.4	Yes	No	0	9	9
219	R:R:Q338	R:R:Y331	13.53	No	No	0	8	7
220	R:R:F341	R:R:Y331	7.22	No	No	0	6	7
221	R:R:K342	R:R:Y331	3.58	No	No	0	5	7
222	R:R:H340	R:R:S336	5.58	Yes	No	0	5	6
223	R:R:H340	R:R:K339	5.24	Yes	No	0	5	4
224	R:R:F346	R:R:K342	3.72	No	No	0	4	5
225	R:R:E264	R:R:K267	2.7	No	Yes	0	4	5
226	R:R:A143	R:R:Y236	2.67	No	Yes	0	6	7
227	R:R:H217	R:R:I216	2.65	No	No	0	6	5
228	R:R:R127	R:R:S124	2.64	No	No	0	6	5
229	R:R:F136	R:R:S175	2.64	No	Yes	0	6	8
230	R:R:F337	R:R:S334	2.64	Yes	No	0	9	8
231	R:R:F136	R:R:V174	2.62	No	No	0	6	4
232	R:R:F178	R:R:V174	2.62	No	No	0	5	4
233	R:R:F328	R:R:V325	2.62	No	No	0	7	6
234	R:R:F314	R:R:I50	2.51	No	No	0	5	5
235	R:R:F311	R:R:M307	2.49	No	No	0	5	3
236	R:R:K267	R:R:R271	2.48	Yes	No	0	5	7
237	R:R:F125	R:R:L180	2.44	No	No	0	6	4
238	R:R:E111	R:R:F115	2.33	No	No	0	3	6
239	R:R:A168	R:R:G169	1.95	No	No	0	8	4
240	R:R:G92	R:R:S130	1.86	No	No	0	8	8
241	R:R:G61	R:R:V60	1.84	No	No	0	8	6
242	R:R:G119	R:R:V122	1.84	No	No	0	5	4
243	R:R:A241	R:R:A270	1.79	No	No	0	5	7
244	R:R:G119	R:R:I118	1.76	No	No	0	5	3
245	R:R:G61	R:R:L97	1.71	No	Yes	0	8	6
246	R:R:A168	R:R:S88	1.71	No	No	0	8	9
247	R:R:C170	R:R:V174	1.71	No	No	0	3	4
248	R:R:C120	R:R:T106	1.69	No	No	0	9	5
249	R:R:K151	R:R:P152	1.67	No	No	0	6	8
250	R:R:C324	R:R:I57	1.64	No	No	0	7	8
251	R:R:C348	R:R:I67	1.64	No	Yes	0	3	7
252	R:R:C165	R:R:I84	1.64	No	No	0	4	5
253	R:R:C165	R:R:I161	1.64	No	No	0	4	3
254	R:R:L180	R:R:P181	1.64	No	No	0	4	7
255	R:R:S59	R:R:V60	1.62	No	No	0	5	6
256	R:R:D303	R:R:P304	1.61	No	No	0	2	1
257	R:R:V56	R:R:V60	1.6	No	No	0	5	6
258	R:R:C48	R:R:L47	1.59	No	No	0	5	3
259	R:R:T300	R:R:V302	1.59	No	No	0	2	1
260	R:R:A241	R:R:L274	1.58	No	No	0	5	5
261	R:R:A278	R:R:L282	1.58	No	No	0	4	6
262	R:R:A281	R:R:L282	1.58	No	No	0	5	6
263	R:R:C283	R:R:N322	1.57	No	Yes	0	8	9
264	R:R:A160	R:R:N159	1.56	No	Yes	0	7	6
265	R:R:A319	R:R:N287	1.56	No	No	0	8	7
266	R:R:I227	R:R:S231	1.55	No	No	0	4	4
267	R:R:I52	R:R:V56	1.54	No	No	0	5	5
268	R:R:A143	R:R:D144	1.54	No	No	0	6	8
269	R:R:I228	R:R:V224	1.54	No	No	0	5	5
270	R:R:M307	R:R:S305	1.53	No	No	0	3	2
271	R:R:I50	R:R:T53	1.52	No	No	0	5	5
272	R:R:I173	R:R:I177	1.47	No	No	0	3	4
273	R:R:L276	R:R:T272	1.47	No	No	0	8	8
274	R:R:Q214	R:R:S218	1.44	No	No	0	3	5
275	R:R:I62	R:R:L98	1.43	No	No	0	6	4
276	R:R:I216	R:R:L212	1.43	No	No	0	5	1
277	R:R:K163	R:R:N159	1.4	No	Yes	0	4	6
278	R:R:L220	R:R:L223	1.38	No	No	0	4	5
279	R:R:I184	R:R:Q214	1.37	No	No	0	5	3
280	R:R:K335	R:R:Q338	1.36	No	No	0	5	8
281	R:R:F296	R:R:T297	1.3	No	No	0	5	4
282	R:R:E254	R:R:E255	1.27	No	No	0	4	1
283	R:R:V277	R:R:Y237	1.26	No	Yes	0	8	9
284	R:R:K246	R:R:R242	1.24	No	No	0	4	4
285	R:R:L114	R:R:W113	1.14	No	No	0	3	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:N65	6.15	4	0	9
2	R:R:I67	6.875	4	0	7
3	R:R:L68	4.29	4	0	9
4	R:R:I69	4.4475	4	5	7
5	R:R:V71	4.3575	4	3	7
6	R:R:T75	6.1775	4	3	5
7	R:R:M78	4.22	6	3	7
8	R:R:F85	4.72	5	1	8
9	R:R:L89	6.28333	6	1	9
10	R:R:D93	7.512	5	1	9
11	R:R:L96	4.16	4	0	7
12	R:R:L97	4.27	4	0	6
13	R:R:Y108	7.45167	6	2	5
14	R:R:T129	4.7925	4	6	5
15	R:R:N159	4.86	5	1	6
16	R:R:T164	5.5025	4	1	7
17	R:R:S175	4.4025	4	0	8
18	R:R:L219	7.18	5	4	5
19	R:R:Y226	7.116	5	1	8
20	R:R:Y236	6.8325	4	0	7
21	R:R:Y237	6.378	5	7	9
22	R:R:L244	3.696	5	8	8
23	R:R:I251	3.368	5	0	4
24	R:R:I263	2.9825	4	0	3
25	R:R:K267	2.9175	4	0	5
26	R:R:W284	5.85	5	1	8
27	R:R:L290	7.48	4	0	4
28	R:R:H294	8.175	4	0	4
29	R:R:R316	4.825	4	2	5
30	R:R:F320	5.436	5	2	7
31	R:R:N322	6.285	4	1	9
32	R:R:N326	7.476	5	1	9
33	R:R:F337	6.16	4	0	9
34	R:R:H340	6.35	6	3	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:I313	R:R:Y108	10.5528	3.63	No	Yes	0	4	5
2	R:R:R316	R:R:Y108	26.1067	4.12	Yes	Yes	2	5	5
3	R:R:F320	R:R:R316	47.631	5.34	Yes	Yes	2	7	5
4	R:R:F320	R:R:L97	49.1086	3.65	Yes	Yes	0	7	6
5	R:R:C324	R:R:G61	12.1261	3.92	No	No	0	7	8
6	R:R:G61	R:R:L97	21.9072	1.71	No	Yes	0	8	6
7	R:R:L97	R:R:S323	69.6458	6.01	Yes	No	0	6	9
8	R:R:D93	R:R:S323	88.3943	10.31	Yes	No	0	9	9
9	R:R:D93	R:R:N65	30.3362	8.08	Yes	Yes	0	9	9
10	R:R:A90	R:R:N65	11.6356	3.13	No	Yes	0	9	9
11	R:R:A90	R:R:L68	10.3553	4.73	No	Yes	0	9	9
12	R:R:F337	R:R:L68	39.7164	4.87	Yes	Yes	0	9	9
13	R:R:F337	R:R:M78	34.452	3.73	Yes	Yes	0	9	7
14	R:R:M78	R:R:V71	30.396	3.04	Yes	Yes	3	7	7
15	R:R:Q344	R:R:V71	28.7688	4.3	No	Yes	0	5	7
16	R:R:I67	R:R:Q344	24.4736	2.74	Yes	No	0	7	5
17	R:R:N65	R:R:P327	11.7313	6.52	Yes	No	0	9	9
18	R:R:L68	R:R:P327	35.5707	3.28	Yes	No	0	9	9
19	R:R:D93	R:R:N326	12.2577	6.73	Yes	Yes	1	9	9
20	R:R:N326	R:R:P327	28.0869	3.26	Yes	No	0	9	9
21	R:R:F341	R:R:I67	15.7394	18.84	No	Yes	0	6	7
22	R:R:L94	R:R:N65	13.52	6.87	No	Yes	0	7	9
23	R:R:I69	R:R:L94	11.6236	2.85	Yes	No	0	7	7
24	R:R:M78	R:R:N83	15.189	4.21	Yes	No	0	7	8
25	R:R:D93	R:R:L89	64.9797	9.5	Yes	Yes	1	9	9
26	R:R:L141	R:R:L89	71.967	2.77	No	Yes	1	9	9
27	R:R:F85	R:R:L141	96.1713	3.65	Yes	No	1	8	9
28	R:R:F85	R:R:T164	22.649	5.19	Yes	Yes	1	8	7
29	R:R:T164	R:R:V81	15.9787	6.35	Yes	No	1	7	6
30	R:R:P82	R:R:V81	15.3565	3.53	No	No	0	8	6
31	R:R:N83	R:R:T80	14.3575	7.31	No	No	0	8	8
32	R:R:P82	R:R:T80	14.1182	10.49	No	No	0	8	8
33	R:R:D144	R:R:F85	99.665	5.97	No	Yes	1	8	8
34	R:R:L89	R:R:T137	34.8947	5.9	Yes	No	1	9	7
35	R:R:S88	R:R:T137	58.3752	4.8	No	No	0	9	7
36	R:R:S88	R:R:W172	54.6423	6.18	No	No	0	9	9
37	R:R:C100	R:R:L96	17.911	3.17	No	Yes	0	6	7
38	R:R:C100	R:R:R127	15.7454	2.79	No	No	0	6	6
39	R:R:R127	R:R:T99	11.8449	5.17	No	No	0	6	6
40	R:R:V133	R:R:W172	53.374	17.16	No	No	0	7	9
41	R:R:S175	R:R:V133	52.0938	6.46	Yes	No	0	8	7
42	R:R:S175	R:R:T129	16.4453	4.8	Yes	Yes	0	8	5
43	R:R:G132	R:R:S175	29.9832	3.71	No	Yes	0	7	8
44	R:R:F225	R:R:G132	28.4996	3.01	No	No	0	6	7
45	R:R:A143	R:R:D144	100	1.54	No	No	0	6	8
46	R:R:A143	R:R:Y236	99.3001	2.67	No	Yes	0	6	7
47	R:R:S142	R:R:Y236	87.826	6.36	No	Yes	0	9	7
48	R:R:S142	R:R:Y237	85.6724	12.72	No	Yes	7	9	9
49	R:R:V235	R:R:Y236	17.9588	3.79	No	Yes	0	4	7
50	R:R:L239	R:R:V235	16.3855	2.98	No	No	0	5	4
51	R:R:L239	R:R:Y146	11.5937	8.21	No	No	0	5	8
52	R:R:V273	R:R:Y237	83.1658	7.57	No	Yes	0	8	9
53	R:R:I240	R:R:V273	37.1979	3.07	No	No	0	8	8
54	R:R:I240	R:R:L244	34.6853	2.85	No	Yes	8	8	8
55	R:R:I269	R:R:V273	45.1005	3.07	No	No	0	7	8
56	R:R:I269	R:R:L244	35.7801	4.28	No	Yes	0	7	8
57	R:R:F222	R:R:F225	20.9021	3.22	No	No	0	6	6
58	R:R:F222	R:R:L219	14.5729	3.65	No	Yes	4	6	5
59	R:R:R316	R:R:T312	25.7059	3.88	Yes	No	0	5	4
60	R:R:L290	R:R:T312	15.6916	2.95	Yes	No	0	4	4
61	R:R:L290	R:R:S315	16.212	4.5	Yes	No	0	4	6
62	R:R:N287	R:R:S315	14.519	4.47	No	No	0	7	6
63	R:R:H288	R:R:N287	16.7803	3.83	No	No	0	7	7
64	R:R:W284	R:R:Y226	15.3207	3.86	Yes	Yes	1	8	8
65	R:R:L244	R:R:R266	38.1431	3.64	Yes	No	0	8	7
66	R:R:A270	R:R:L244	30.2405	4.73	No	Yes	0	7	8
67	R:R:A270	R:R:Y245	22.1285	6.67	No	No	0	7	5
68	R:R:K267	R:R:Y245	19.4365	3.58	Yes	No	0	5	5
69	R:R:Q262	R:R:R266	30.073	5.84	No	No	0	4	7
70	R:R:I251	R:R:Q262	27.381	2.74	Yes	No	0	4	4
71	R:R:I251	R:R:I263	11.474	2.94	Yes	Yes	0	4	3
72	R:R:I263	R:R:T248	11.139	3.04	Yes	No	0	3	4
73	R:R:I263	R:R:K267	11.3903	2.91	Yes	Yes	0	3	5
74	R:R:I251	R:R:P252	11.4082	5.08	Yes	No	0	4	4
75	R:R:I269	R:R:L333	10.457	7.14	No	No	0	7	6
76	R:R:N322	R:R:N326	39.1721	9.54	Yes	Yes	1	9	9
77	R:R:N322	R:R:W284	29.8576	6.78	Yes	Yes	1	9	8
78	R:R:H294	R:R:L290	14.9916	10.29	Yes	Yes	0	4	4
79	R:R:H294	R:R:Y293	14.7583	6.53	Yes	No	0	4	5
80	R:R:T297	R:R:Y293	11.0852	9.99	No	No	0	4	5
81	R:R:F341	R:R:Y331	11.3006	7.22	No	No	0	6	7
82	R:R:H288	R:R:W284	16.0924	4.23	No	Yes	1	7	8
83	R:R:L96	R:R:S323	22.1405	4.5	Yes	No	0	7	9
84	R:R:L89	R:R:N326	40.8591	9.61	Yes	Yes	1	9	9
85	R:R:L141	R:R:T137	24.6949	2.95	No	No	1	9	7

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 8Y51_nogp

PDB Summary
PDB	8Y51_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	2.74
Number of Linked Nodes	250
Number of Links	285
Number of Hubs	34
Number of Links mediated by Hubs	131
Number of Communities	8
Number of Nodes involved in Communities	47
Number of Links involved in Communities	63

Path Summary
Number Of Nodes in MetaPath	86
Number Of Links MetaPath	85
Number of Shortest Paths	41188
Length Of Smallest Path	3
Average Path Length	14.4923
Length of Longest Path	29
Minimum Path Strength	1.405
Average Path Strength	5.44454
Maximum Path Strength	14.24
Minimum Path Correlation	0.7
Average Path Correlation	0.929055
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	4
Average % Of Corr. Nodes	52.1545
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	41.3417
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P32247
Sequence	>8Y51_nogp_Chain_R L C A I Y I T Y A V I I S V G I L G N A I L I K V F F K T K S M Q T V P N I F I T S L A F G D L L L L L T C V P V D A T H Y L A E G W L F G R I G C K V L S F I R L T S V G V S V F T L T I L S A D R Y K A V V K P L E R Q N A I L K T C V K A G C V W I V S M I F A L P E A I F K L L Q E I H S L L C F L V F Y I I P L S I I S V Y Y S L I A R T L Y K S T L N I P T E E Q S H A R K Q I E S R K R I A R T V L V L V A L F A L C W L P N H L L Y L Y H S F T S Q T Y V D P S A M H F I F T I F S R V L A F S N S C V N P F A L Y W L S K S F Q K H F K A Q L F C C K Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8Y52	A	Peptide	Bombesin	BB₃	Homo sapiens	BA1	-	chim(NtGi1-Gs-CtGq)/β1/γ2	2.9	2024-09-11	doi.org/10.1016/j.celrep.2024.114511
	8Y52 (No Gprot)	A	Peptide	Bombesin	BB₃	Homo sapiens	BA1	-		2.9	2024-09-11	doi.org/10.1016/j.celrep.2024.114511
	8Y53	A	Peptide	Bombesin	BB₃	Homo sapiens	MK5046	-	chim(NtGi1-Gs-CtGq)/β1/γ2	2.93	2024-09-11	doi.org/10.1016/j.celrep.2024.114511
	8Y53 (No Gprot)	A	Peptide	Bombesin	BB₃	Homo sapiens	MK5046	-		2.93	2024-09-11	doi.org/10.1016/j.celrep.2024.114511
	8Y51	A	Peptide	Bombesin	BB₃	Homo sapiens	-	-	chim(NtGi1-Gs-CtGq)/β1/γ2	3.3	2025-02-12	To be published
	8Y51 (No Gprot)	A	Peptide	Bombesin	BB₃	Homo sapiens	-	-		3.3	2025-02-12	To be published
	9K07	A	Peptide	Bombesin	BB₃	Homo sapiens	DSO-5a	-	chim(NtGi2L-Gs-CtGq)/β1/γ2	2.87	2025-08-27	/doi.org/10.1016/j.apsb.2025.06.025
	9K07 (No Gprot)	A	Peptide	Bombesin	BB₃	Homo sapiens	DSO-5a	-		2.87	2025-08-27	/doi.org/10.1016/j.apsb.2025.06.025
	9LWP	A	Peptide	Bombesin	BB₃	Homo sapiens	-	-	chim(NtGi2L-Gs-CtGq)/β1/γ2	2.93	2025-07-16	doi.org/10.1016/j.apsb.2025.06.025
	9LWP (No Gprot)	A	Peptide	Bombesin	BB₃	Homo sapiens	-	-		2.93	2025-07-16	doi.org/10.1016/j.apsb.2025.06.025

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 8Y51_nogp.zip

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