Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index Hub Avg Int. Strength Num Of Links Community ConSurf
1R:R:Y54 11.8775447
2R:R:I58 4.8975447
3R:R:I62 3.59446
4R:R:F72 8.1875407
5R:R:M78 4.934527
6R:R:V81 4.6225406
7R:R:F85 6.302508
8R:R:I86 3.2025408
9R:R:L97 6.356546
10R:R:F136 4.1475466
11R:R:Y146 10.025408
12R:R:V149 4.645439
13R:R:E182 7.0075405
14R:R:Y206 8.622503
15R:R:Q214 3.6475403
16R:R:F222 6.265416
17R:R:F225 4.5466
18R:R:Y226 7.2325418
19R:R:Y237 7.108509
20R:R:L244 3.094538
21R:R:I251 4.854534
22R:R:R266 4.0425437
23R:R:W284 5.162518
24R:R:L292 4.5075415
25R:R:S295 4.9414
26R:R:F320 7.63667647
27R:R:N322 6.295419
28R:R:Y331 7.595407
29R:R:F337 4.705409
   

Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index Node1 Node2 Recurrence Int. Strength Hub1? Hub2? Community ConSurf1 ConSurf2
1R:R:L290 R:R:S315 13.05143NoNo046
2R:R:P286 R:R:S315 14.9415.34NoNo096
3R:R:L285 R:R:P286 20.44953.28NoNo069
4R:R:L285 R:R:Y226 24.04579.38NoYes068
5R:R:H288 R:R:W284 37.61523.17NoYes178
6R:R:V131 R:R:W284 25.3796.13NoYes088
7R:R:L96 R:R:V131 24.32764.47NoNo078
8R:R:L96 R:R:S130 23.91626.01NoNo078
9R:R:L95 R:R:S130 24.69333NoNo068
10R:R:I126 R:R:L95 25.282.85NoNo056
11R:R:I126 R:R:T99 25.88199.12NoNo056
12R:R:L123 R:R:T99 27.08572.95NoNo056
13R:R:L123 R:R:P102 27.71814.93NoNo058
14R:R:P102 R:R:V101 33.6993.53NoNo087
15R:R:I58 R:R:V101 34.43.07YesNo077
16R:R:F320 R:R:I58 25.32575.02YesYes477
17R:R:F320 R:R:I57 20.51815.02YesNo078
18R:R:I57 R:R:V56 14.68191.54NoNo085
19R:R:I52 R:R:V56 11.7411.54NoNo055
20R:R:F320 R:R:Y54 14.521917.54YesYes477
21R:R:D104 R:R:Y54 11.718119.54NoYes067
22R:R:I58 R:R:I62 36.41142.94YesYes476
23R:R:F341 R:R:I67 14.057112.56NoNo067
24R:R:F341 R:R:Y331 17.56959.28NoYes067
25R:R:F337 R:R:Y331 31.46674.13YesYes097
26R:R:F337 R:R:L68 33.97336.09YesNo099
27R:R:I86 R:R:L68 35.53522.85YesNo089
28R:R:I86 R:R:L141 1002.85YesNo089
29R:R:F85 R:R:L141 94.94863.65YesNo089
30R:R:F85 R:R:I140 86.14867.54YesNo086
31R:R:I140 R:R:V171 84.74673.07NoNo067
32R:R:F136 R:R:V171 84.03813.93YesNo067
33R:R:F136 R:R:F225 70.13335.36YesYes666
34R:R:C221 R:R:F225 71.29144.19NoYes056
35R:R:C221 R:R:H217 70.49147.37NoNo056
36R:R:H217 R:R:Y206 68.091420.69NoYes063
37R:R:Q214 R:R:Y206 61.28764.51YesYes033
38R:R:Q214 R:R:S295 58.07244.33YesYes034
39R:R:L292 R:R:S295 54.10293YesYes154
40R:R:F222 R:R:L292 54.13334.87YesYes165
41R:R:F222 R:R:Y226 21.30298.25YesYes168
42R:R:F337 R:R:L330 34.02674.87YesNo099
43R:R:I86 R:R:L330 35.39814.28YesNo089
44R:R:F91 R:R:I69 68.10675.02NoNo067
45R:R:I69 R:R:L94 67.52761.43NoNo077
46R:R:I62 R:R:L94 67.1011.43YesNo067
47R:R:F337 R:R:M78 34.76573.73YesYes097
48R:R:M78 R:R:V71 14.10293.04YesNo277
49R:R:Q344 R:R:V71 10.66672.87NoNo257
50R:R:H340 R:R:M78 10.567611.82NoYes257
51R:R:F72 R:R:N83 72.37334.83YesNo078
52R:R:I86 R:R:N83 73.32572.83YesNo088
53R:R:F72 R:R:F73 69.287612.86YesNo074
54R:R:F73 R:R:F91 68.63243.22NoNo046
55R:R:F85 R:R:T164 21.363810.38YesNo087
56R:R:T164 R:R:V81 17.61526.35NoYes076
57R:R:N322 R:R:N326 11.7414.09YesNo099
58R:R:N322 R:R:W284 17.97337.91YesYes198
59R:R:F115 R:R:P102 12.82292.89NoNo068
60R:R:E182 R:R:S205 13.13528.62YesNo054
61R:R:S205 R:R:Y206 15.01718.9NoYes043
62R:R:G132 R:R:S175 13.8593.71NoNo078
63R:R:L141 R:R:R145 85.0217.29NoNo099
64R:R:R145 R:R:Y237 83.794310.29NoYes099
65R:R:S142 R:R:Y237 76.114312.72NoYes099
66R:R:I233 R:R:S142 13.80574.64NoNo089
67R:R:I233 R:R:T139 11.87813.04NoNo087
68R:R:S142 R:R:Y236 65.0215.09NoNo097
69R:R:Y146 R:R:Y236 62.095216.88YesNo087
70R:R:V150 R:R:Y146 49.782912.62NoYes078
71R:R:V149 R:R:V150 42.89523.21YesNo397
72R:R:L244 R:R:V149 39.87052.98YesYes389
73R:R:A270 R:R:L244 11.83243.15NoYes078
74R:R:L244 R:R:R266 19.13143.64YesYes387
75R:R:I251 R:R:R266 13.58483.76YesYes347
76R:R:I62 R:R:L97 29.8597.14YesYes466
77R:R:F320 R:R:L97 17.70674.87YesYes476
78R:R:F222 R:R:H288 31.5815.66YesNo167
79R:R:F136 R:R:G132 11.08573.01YesNo667
Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


PDB Summary
PDB 9LWP_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.
Net Summary
Imin 2.85
Number of Linked Nodes 251
Number of Links 264
Number of Hubs 29
Number of Links mediated by Hubs 108
Number of Communities 7
Number of Nodes involved in Communities 41
Number of Links involved in Communities 50
Path Summary
Number Of Nodes in MetaPath 80
Number Of Links MetaPath 79
Number of Shortest Paths 32522
Length Of Smallest Path 3
Average Path Length 15.6707
Length of Longest Path 34
Minimum Path Strength 1.155
Average Path Strength 5.75626
Maximum Path Strength 14.795
Minimum Path Correlation 0.7
Average Path Correlation 0.930322
Maximum Path Correlation 0.99
Minimum % Of Corr. Nodes 3.22581
Average % Of Corr. Nodes 44.6974
Maximum % Of Corr. Nodes 100
Minimum Path Hubs % 0
Average Path Hubs % 38.6313
Maximum Path Hubs % 100
AnnotationTypeLinks
Gene OntologyMolecular Function
Gene OntologyBiological Process• cellular response to nitrogen compound   • cellular response to stimulus   • response to dopamine   • regulation of cellular process   • response to stimulus   • signaling   • cellular response to dopamine   • response to monoamine   • cell communication   • response to catecholamine   • adenylate cyclase-activating dopamine receptor signaling pathway   • cellular response to catecholamine stimulus   • signal transduction   • regulation of biological process   • G protein-coupled dopamine receptor signaling pathway   • biological regulation   • response to oxygen-containing compound   • response to nitrogen compound   • adenylate cyclase-activating G protein-coupled receptor signaling pathway   • cellular response to oxygen-containing compound   • cellular response to chemical stimulus   • cellular response to monoamine stimulus   • response to chemical   • adenylate cyclase-modulating G protein-coupled receptor signaling pathway   • cellular process   • G protein-coupled receptor signaling pathway   • response to ketone   • response to prostaglandin   • response to lipid   • response to endogenous stimulus   • response to alcohol   • cellular response to prostaglandin stimulus   • cellular response to endogenous stimulus   • cellular response to prostaglandin E stimulus   • cellular response to alcohol   • response to hormone   • cellular response to lipid   • response to prostaglandin E   • cellular response to ketone   • cellular response to hormone stimulus   • cell periphery   • cellular anatomical structure   • plasma membrane   • membrane   • protein-containing complex   • extrinsic component of plasma membrane   • catalytic complex   • plasma membrane protein complex   • cytoplasmic side of membrane   • membrane protein complex   • heterotrimeric G-protein complex   • side of membrane   • cytoplasmic side of plasma membrane   • GTPase complex
Gene OntologyCellular Component• cell periphery   • cellular anatomical structure   • plasma membrane   • membrane   • protein-containing complex   • extrinsic component of plasma membrane   • catalytic complex   • plasma membrane protein complex   • cytoplasmic side of membrane   • membrane protein complex   • heterotrimeric G-protein complex   • side of membrane   • cytoplasmic side of plasma membrane   • GTPase complex   • extrinsic component of membrane   • extrinsic component of cytoplasmic side of plasma membrane   • cytoskeletal protein binding   • spectrin binding   • protein-containing complex binding   • protein binding   • binding   • enzyme binding   • GTPase binding   • phosphoric ester hydrolase activity   • alkylglycerophosphoethanolamine phosphodiesterase activity   • hydrolase activity, acting on ester bonds   • phosphoric diester hydrolase activity   • hydrolase activity   • catalytic activity   • pyrophosphatase activity   • GTPase activity   • ribonucleoside triphosphate phosphatase activity   • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides   • hydrolase activity, acting on acid anhydrides   • signaling receptor complex adaptor activity   • protein-macromolecule adaptor activity   • molecular adaptor activity   • signaling adaptor activity   • positive regulation of cytosolic calcium ion concentration   • biological regulation   • regulation of biological quality   • multicellular organismal process   • system process   • sensory perception of chemical stimulus   • sensory perception   • nervous system process   • sensory perception of taste   • developmental process   • sensory organ development   • eye development   • animal organ development   • retina development in camera-type eye   • visual system development   • multicellular organism development   • camera-type eye development   • anatomical structure development   • sensory system development   • system development   • response to decreased oxygen levels   • cellular response to stimulus   • response to stimulus   • cellular response to oxygen levels   • cellular response to hypoxia   • cellular response to decreased oxygen levels   • cellular response to chemical stimulus   • cellular response to stress   • response to hypoxia   • response to stress   • response to chemical   • response to oxygen levels   • response to abiotic stimulus   • cellular process   • cell population proliferation   • regulation of biological process   • regulation of cellular process   • signaling   • phospholipase C-activating G protein-coupled receptor signaling pathway   • cell communication   • G protein-coupled receptor signaling pathway   • signal transduction   • muscle cell apoptotic process   • striated muscle cell apoptotic process   • apoptotic process   • cell death   • programmed cell death   • cardiac muscle cell apoptotic process   • photoreceptor inner segment   • somatodendritic compartment   • cell projection   • dendrite   • dendritic tree   • neuron projection   • plasma membrane bounded cell projection   • intracellular anatomical structure   • cytoplasm   • membrane-bounded organelle   • non-motile cilium   • 9+0 non-motile cilium   • cilium   • photoreceptor outer segment   • photoreceptor cell cilium   • organelle   • ciliary membrane   • photoreceptor outer segment membrane   • bounding membrane of organelle   • plasma membrane region   • organelle membrane   • cell projection membrane   • synapse   • cell junction   • cell body   • guanyl nucleotide binding   • GTP binding   • nucleotide binding   • guanyl ribonucleotide binding   • purine ribonucleotide binding   • purine ribonucleoside triphosphate binding   • nucleoside phosphate binding   • ion binding   • purine nucleotide binding   • anion binding   • heterocyclic compound binding   • carbohydrate derivative binding   • ribonucleotide binding   • small molecule binding   • G-protein beta/gamma-subunit complex binding   • signaling receptor binding   • G protein-coupled receptor binding   • cation binding   • metal ion binding   • D1 dopamine receptor binding   • dopamine receptor binding   • G protein activity   • molecular function regulator activity   • enzyme regulator activity   • cyclase regulator activity   • enzyme activator activity   • cyclase activator activity   • molecular function activator activity   • adenylate cyclase regulator activity   • adenylate cyclase activator activity   • positive regulation of cell population proliferation   • positive regulation of biological process   • positive regulation of neural precursor cell proliferation   • regulation of cell population proliferation   • neural precursor cell proliferation   • positive regulation of cellular process   • regulation of neural precursor cell proliferation   • reactive oxygen species metabolic process   • regulation of superoxide metabolic process   • positive regulation of reactive oxygen species metabolic process   • superoxide metabolic process   • positive regulation of metabolic process   • superoxide anion generation   • metabolic process   • positive regulation of superoxide anion generation   • regulation of superoxide anion generation   • regulation of metabolic process   • regulation of reactive oxygen species metabolic process   • regulation of calcium ion transport   • regulation of localization   • transport   • regulation of transport   • regulation of monoatomic ion transport   • establishment of localization   • metal ion transport   • calcium ion transport   • localization   • monoatomic ion transport   • regulation of metal ion transport   • monoatomic cation transport   • positive regulation of cell communication   • positive regulation of signal transduction   • regulation of signal transduction   • intracellular signal transduction   • positive regulation of response to stimulus   • positive regulation of ERK1 and ERK2 cascade   • regulation of intracellular signal transduction   • intracellular signaling cassette   • regulation of signaling   • positive regulation of MAPK cascade   • positive regulation of intracellular signal transduction   • regulation of MAPK cascade   • regulation of response to stimulus   • MAPK cascade   • regulation of cell communication   • ERK1 and ERK2 cascade   • regulation of ERK1 and ERK2 cascade   • positive regulation of signaling   • negative regulation of signaling   • negative regulation of biological process   • negative regulation of G protein-coupled receptor signaling pathway   • negative regulation of cell communication   • negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway   • adrenergic receptor signaling pathway   • negative regulation of cellular process   • regulation of G protein-coupled receptor signaling pathway   • adenylate cyclase-activating adrenergic receptor signaling pathway   • negative regulation of response to stimulus   • adenylate cyclase-activating G protein-coupled receptor signaling pathway   • negative regulation of signal transduction   • negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway   • adenylate cyclase-modulating G protein-coupled receptor signaling pathway   • regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway   • cell division   • regulation of body fluid levels   • renal system process   • positive regulation of urine volume   • regulation of urine volume   • regulation of vascular associated smooth muscle cell proliferation   • positive regulation of vascular associated smooth muscle cell proliferation   • regulation of smooth muscle cell proliferation   • smooth muscle cell proliferation   • positive regulation of smooth muscle cell proliferation   • muscle cell proliferation   • vascular associated smooth muscle cell proliferation   • cell-cell signaling   • gamma-aminobutyric acid signaling pathway   • purinergic nucleotide receptor signaling pathway   • cell surface receptor signaling pathway   • G protein-coupled purinergic receptor signaling pathway   • G protein-coupled adenosine receptor signaling pathway   • regulation of molecular function   • regulation of adenylate cyclase activity   • regulation of catalytic activity   • negative regulation of molecular function   • negative regulation of catalytic activity   • negative regulation of adenylate cyclase activity   • regulated exocytosis   • regulation of calcium ion-dependent exocytosis   • negative regulation of transport   • negative regulation of regulated secretory pathway   • vesicle-mediated transport   • regulation of regulated secretory pathway   • secretion by cell   • regulation of secretion by cell   • negative regulation of secretion   • negative regulation of exocytosis   • negative regulation of secretion by cell   • calcium-ion regulated exocytosis   • secretion   • negative regulation of calcium ion-dependent exocytosis   • export from cell   • regulation of vesicle-mediated transport   • regulation of secretion   • exocytosis   • regulation of exocytosis   • regulation of programmed cell death   • negative regulation of apoptotic signaling pathway   • negative regulation of programmed cell death   • regulation of apoptotic process   • apoptotic signaling pathway   • negative regulation of apoptotic process   • regulation of apoptotic signaling pathway   • positive regulation of locomotion   • regulation of cell motility   • positive regulation of cell migration   • regulation of locomotion   • positive regulation of cell motility   • regulation of cell migration   • cell migration   • cell motility   • locomotion   • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway   • trans-synaptic signaling   • modulation of chemical synaptic transmission   • negative regulation of synaptic transmission   • chemical synaptic transmission   • synaptic signaling   • regulation of trans-synaptic signaling   • anterograde trans-synaptic signaling   • cellular response to nitrogen compound   • cellular response to acetylcholine   • response to oxygen-containing compound   • response to nitrogen compound   • acetylcholine receptor signaling pathway   • postsynaptic signal transduction   • cellular response to oxygen-containing compound   • G protein-coupled acetylcholine receptor signaling pathway   • response to acetylcholine   • response to nutrient levels   • response to nutrient   • epithelium development   • ectodermal placode morphogenesis   • epidermis development   • molting cycle process   • hair cycle   • hair follicle placode formation   • tissue development   • ectodermal placode formation   • anatomical structure morphogenesis   • skin development   • skin epidermis development   • hair follicle development   • molting cycle   • anatomical structure formation involved in morphogenesis   • ectodermal placode development   • hair cycle process   • sensory perception of smell   • response to endogenous stimulus   • response to peptide hormone   • cellular response to peptide hormone stimulus   • response to glucagon   • cellular response to glucagon stimulus   • cellular response to endogenous stimulus   • response to hormone   • cellular response to hormone stimulus   • skeletal system development   • bone development   • wound healing   • homotypic cell-cell adhesion   • cell activation   • hemostasis   • platelet aggregation   • blood coagulation   • cell adhesion   • cell-cell adhesion   • coagulation   • response to wounding   • platelet activation   • response to fluid shear stress   • vascular endothelial cell response to laminar fluid shear stress   • response to laminar fluid shear stress   • cellular response to laminar fluid shear stress   • vascular endothelial cell response to fluid shear stress   • cellular response to fluid shear stress   • cognition   • developmental growth   • growth   • response to ketone   • response to prostaglandin   • response to lipid   • response to alcohol   • cellular response to prostaglandin stimulus   • cellular response to prostaglandin E stimulus   • cellular response to alcohol   • cellular response to lipid   • response to prostaglandin E   • cellular response to ketone   • homeostatic process   • adaptive thermogenesis   • multicellular organismal-level homeostasis   • regulation of cold-induced thermogenesis   • cold-induced thermogenesis   • temperature homeostasis   • positive regulation of cold-induced thermogenesis   • positive regulation of multicellular organismal process   • regulation of multicellular organismal process   • establishment of protein localization   • nitrogen compound transport   • regulation of hormone secretion   • regulation of protein localization   • regulation of peptide secretion   • hormone secretion   • protein localization to extracellular region   • peptide secretion   • amide transport   • signal release   • intracellular protein localization   • regulation of peptide hormone secretion   • regulation of hormone levels   • regulation of peptide transport   • regulation of establishment of protein localization   • establishment of protein localization to extracellular region   • regulation of protein transport   • protein secretion   • regulation of protein secretion   • peptide transport   • protein transport   • regulation of insulin secretion   • peptide hormone secretion   • macromolecule localization   • hormone transport   • insulin secretion   • cellular localization   • establishment of localization in cell   • intracellular transport   • regulation of defense response   • regulation of response to external stimulus   • negative regulation of inflammatory response   • inflammatory response to antigenic stimulus   • regulation of response to stress   • regulation of immune system process   • negative regulation of inflammatory response to antigenic stimulus   • defense response   • immune response   • negative regulation of immune response   • regulation of inflammatory response to antigenic stimulus   • response to external stimulus   • regulation of inflammatory response   • negative regulation of immune system process   • immune system process   • negative regulation of response to external stimulus   • negative regulation of defense response   • regulation of immune response   • inflammatory response   • positive regulation of adenylate cyclase activity   • positive regulation of molecular function   • positive regulation of cyclase activity   • activation of adenylate cyclase activity   • positive regulation of catalytic activity   • positive regulation of lyase activity   • response to dopamine   • cellular response to dopamine   • response to monoamine   • response to catecholamine   • adenylate cyclase-activating dopamine receptor signaling pathway   • cellular response to catecholamine stimulus   • G protein-coupled dopamine receptor signaling pathway   • cellular response to monoamine stimulus   • chemical homeostasis   • multicellular organismal-level water homeostasis   • multicellular organismal-level chemical homeostasis   • renal water homeostasis   • midbody   • dense core granule   • intracellular vesicle   • intracellular membrane-bounded organelle   • endomembrane system   • intracellular organelle   • cytoplasmic vesicle   • secretory granule   • secretory vesicle   • vesicle   • neuronal dense core vesicle   • extracellular exosome   • extracellular vesicle   • extracellular organelle   • extracellular region   • extracellular space   • extracellular membrane-bounded organelle   • centrosome   • microtubule organizing center   • cytoskeleton   • membraneless organelle   • intracellular membraneless organelle   • microtubule cytoskeleton   • cytosol   • nucleus   • membrane-enclosed lumen   • intracellular organelle lumen   • nucleoplasm   • organelle lumen   • nuclear lumen   • neuron to neuron synapse   • hippocampal mossy fiber to CA3 synapse   • ciliary basal body   • Golgi apparatus subcompartment   • Golgi apparatus   • organelle subcompartment   • trans-Golgi network membrane   • trans-Golgi network   • peptide receptor activity   • molecular transducer activity   • G protein-coupled receptor activity   • G protein-coupled peptide receptor activity   • signaling receptor activity   • transmembrane signaling receptor activity   • neuropeptide receptor activity   • bombesin receptor activity   • oxidoreductase activity   • monooxygenase activity   • Oplophorus-luciferin 2-monooxygenase activity   • oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)   • oxidoreductase activity, acting on single donors with incorporation of molecular oxygen   • luciferin monooxygenase activity   • circulatory system process   • regulation of blood pressure   • blood circulation   • behavior   • adult feeding behavior   • adult behavior   • feeding behavior   • monosaccharide metabolic process   • carbohydrate metabolic process   • hexose metabolic process   • small molecule metabolic process   • primary metabolic process   • glucose metabolic process   • bioluminescence
SCOP2Domain Identifier• Transducin (heterotrimeric G protein), gamma chain
SCOP2Family Identifier• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations-• Orientations of Proteins in Membranes database (OPM)   • Protein Data Bank of Transmembrane Proteins (PDBTM)   • MemProtMD


Details about the values in these tables can be found in the corresponding documentation page .
PDBsumOpen PDBsum Page
ChainR
ProteinReceptor
UniProtP32247
Sequence
>9LWP_nogp_Chain_R
LCAIYITYA VIISVGILG NAILIKVFF KTKSMQTVP NIFITSLAF 
GDLLLLLTC VPVDATHYG WLFGRIGKV LSFIRLTSV GVSVFTLTI 
LSADRYKAV VKPLERQPS NAILKTCVK AGCVWIVSM IFALPEAIF 
CTSYPVSKK LLQEIHSLL CFLVFYIIP LSIISVYYS LIARTLYKS 
TLNIPTEEQ SHARKQIES RKRIARTVL VLVALFALC WLPNHLLYL 
YHSFTSAMH FIFTIFSRV LAFSNSCVN PFALYWLSK SFQKHFKAQ 
L


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  




This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
8Y52APeptideBombesinBB3Homo sapiensBA1-chim(NtGi1-Gs-CtGq)/β1/γ22.92024-09-11doi.org/10.1016/j.celrep.2024.114511
8Y52 (No Gprot) APeptideBombesinBB3Homo sapiensBA1-2.92024-09-11doi.org/10.1016/j.celrep.2024.114511
8Y53APeptideBombesinBB3Homo sapiensMK5046-chim(NtGi1-Gs-CtGq)/β1/γ22.932024-09-11doi.org/10.1016/j.celrep.2024.114511
8Y53 (No Gprot) APeptideBombesinBB3Homo sapiensMK5046-2.932024-09-11doi.org/10.1016/j.celrep.2024.114511
8Y51APeptideBombesinBB3Homo sapiens--chim(NtGi1-Gs-CtGq)/β1/γ23.32025-02-12To be published
8Y51 (No Gprot) APeptideBombesinBB3Homo sapiens--3.32025-02-12To be published
9K07APeptideBombesinBB3Homo sapiensDSO-5a-chim(NtGi2L-Gs-CtGq)/β1/γ22.872025-08-27/doi.org/10.1016/j.apsb.2025.06.025
9K07 (No Gprot) APeptideBombesinBB3Homo sapiensDSO-5a-2.872025-08-27/doi.org/10.1016/j.apsb.2025.06.025
9LWPAPeptideBombesinBB3Homo sapiens--chim(NtGi2L-Gs-CtGq)/β1/γ22.932025-07-16doi.org/10.1016/j.apsb.2025.06.025
9LWP (No Gprot) APeptideBombesinBB3Homo sapiens--2.932025-07-16doi.org/10.1016/j.apsb.2025.06.025




You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 9LWP_nogp.zip



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