psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:C100	3.63	Yes	Yes	1	0	6
2	L:L:?1	R:R:R127	5.56	Yes	No	0	0	6
3	L:L:?1	R:R:L128	9.51	Yes	No	0	0	5
4	L:L:?1	R:R:V131	7.96	Yes	No	1	0	8
5	L:L:?1	R:R:S205	4.58	Yes	No	0	0	4
6	L:L:?1	R:R:H217	2.94	Yes	Yes	1	0	6
7	L:L:?1	R:R:C221	4.85	Yes	No	1	0	5
8	L:L:?1	R:R:F225	3.72	Yes	Yes	1	0	6
9	L:L:?1	R:R:W284	5.22	Yes	Yes	1	0	8
10	L:L:?1	R:R:N287	23.06	Yes	No	0	0	7
11	L:L:?1	R:R:H288	12.76	Yes	Yes	1	0	7
12	L:L:?1	R:R:Y291	8.95	Yes	Yes	1	0	6
13	L:L:?1	R:R:R316	16.69	Yes	No	1	0	5
14	R:R:C48	R:R:Y108	5.38	No	Yes	0	5	5
15	R:R:I313	R:R:I50	4.42	No	No	0	4	5
16	R:R:D104	R:R:Y51	4.6	No	No	0	6	5
17	R:R:I58	R:R:Y54	4.84	No	Yes	1	7	7
18	R:R:C100	R:R:Y54	2.69	Yes	Yes	1	6	7
19	R:R:D104	R:R:Y54	20.69	No	Yes	0	6	7
20	R:R:V317	R:R:Y54	5.05	No	Yes	1	5	7
21	R:R:F320	R:R:Y54	8.25	Yes	Yes	1	7	7
22	R:R:F320	R:R:I57	3.77	Yes	No	0	7	8
23	R:R:I58	R:R:L97	2.85	No	No	0	7	6
24	R:R:F320	R:R:I58	7.54	Yes	No	1	7	7
25	R:R:G61	R:R:V60	3.68	No	Yes	4	8	6
26	R:R:C324	R:R:V60	3.42	No	Yes	4	7	6
27	R:R:F328	R:R:V60	3.93	No	Yes	0	7	6
28	R:R:C324	R:R:G61	3.92	No	No	4	7	8
29	R:R:G64	R:R:L63	3.42	No	No	0	8	4
30	R:R:G64	R:R:I67	3.53	No	No	0	8	7
31	R:R:G64	R:R:P327	4.06	No	No	0	8	9
32	R:R:A90	R:R:N65	3.13	No	No	0	9	9
33	R:R:D93	R:R:N65	16.16	No	No	0	9	9
34	R:R:L94	R:R:N65	5.49	No	No	0	7	9
35	R:R:F341	R:R:I67	5.02	Yes	No	0	6	7
36	R:R:I86	R:R:L68	4.28	No	No	0	8	9
37	R:R:L68	R:R:T87	2.95	No	No	0	9	6
38	R:R:F337	R:R:L68	7.31	No	No	0	9	9
39	R:R:I69	R:R:K70	2.91	No	No	0	7	4
40	R:R:F91	R:R:I69	6.28	No	No	0	6	7
41	R:R:K70	R:R:K74	5.75	No	No	0	4	5
42	R:R:M78	R:R:V71	4.56	Yes	No	2	7	7
43	R:R:H340	R:R:V71	5.54	Yes	No	2	5	7
44	R:R:F72	R:R:F73	4.29	Yes	No	0	7	4
45	R:R:F72	R:R:Q79	5.86	Yes	No	0	7	7
46	R:R:F72	R:R:N83	4.83	Yes	No	0	7	8
47	R:R:F72	R:R:T87	18.16	Yes	No	0	7	6
48	R:R:F73	R:R:F91	4.29	No	No	0	4	6
49	R:R:K74	R:R:Q344	5.42	No	No	0	5	5
50	R:R:S77	R:R:T75	3.2	No	No	2	6	5
51	R:R:M78	R:R:T75	3.01	Yes	No	2	7	5
52	R:R:H340	R:R:T75	8.21	Yes	No	2	5	5
53	R:R:K76	R:R:Q79	2.71	No	No	0	6	7
54	R:R:M78	R:R:S77	3.07	Yes	No	2	7	6
55	R:R:H340	R:R:S77	4.18	Yes	No	2	5	6
56	R:R:M78	R:R:N83	8.41	Yes	No	0	7	8
57	R:R:H340	R:R:M78	9.19	Yes	Yes	2	5	7
58	R:R:T80	R:R:V81	3.17	No	Yes	5	8	6
59	R:R:P82	R:R:T80	6.99	No	No	5	8	8
60	R:R:N83	R:R:T80	4.39	No	No	0	8	8
61	R:R:P82	R:R:V81	3.53	No	Yes	5	8	6
62	R:R:P157	R:R:V81	5.3	No	Yes	0	3	6
63	R:R:T164	R:R:V81	4.76	No	Yes	0	7	6
64	R:R:I84	R:R:T164	7.6	No	No	0	5	7
65	R:R:F85	R:R:T137	5.19	Yes	No	0	8	7
66	R:R:F85	R:R:I140	6.28	Yes	No	0	8	6
67	R:R:F85	R:R:T164	2.59	Yes	No	0	8	7
68	R:R:F85	R:R:K167	3.72	Yes	No	0	8	6
69	R:R:I86	R:R:L141	4.28	No	No	0	8	9
70	R:R:I86	R:R:L330	5.71	No	No	0	8	9
71	R:R:S88	R:R:T137	3.2	No	No	0	9	7
72	R:R:S88	R:R:W172	4.94	No	Yes	0	9	9
73	R:R:L89	R:R:S134	3	Yes	No	0	9	9
74	R:R:L89	R:R:T137	5.9	Yes	No	0	9	7
75	R:R:L138	R:R:L89	4.15	No	Yes	1	8	9
76	R:R:L89	R:R:N326	13.73	Yes	No	1	9	9
77	R:R:G92	R:R:W172	2.81	No	Yes	0	8	9
78	R:R:D93	R:R:L97	8.14	No	No	0	9	6
79	R:R:D93	R:R:S323	8.83	No	No	0	9	9
80	R:R:I126	R:R:L95	2.85	No	No	0	5	6
81	R:R:L96	R:R:S130	4.5	No	No	0	7	8
82	R:R:L96	R:R:S323	3	No	No	0	7	9
83	R:R:I126	R:R:T99	3.04	No	No	0	5	6
84	R:R:R127	R:R:T99	5.17	No	No	0	6	6
85	R:R:C100	R:R:R316	4.18	Yes	No	1	6	5
86	R:R:C100	R:R:F320	2.79	Yes	Yes	1	6	7
87	R:R:P102	R:R:V101	3.53	No	No	0	8	7
88	R:R:F115	R:R:P102	2.89	Yes	No	0	6	8
89	R:R:L123	R:R:P102	4.93	No	No	0	5	8
90	R:R:D104	R:R:Y108	5.75	No	Yes	0	6	5
91	R:R:F115	R:R:T106	3.89	Yes	No	0	6	5
92	R:R:L109	R:R:Y108	7.03	No	Yes	0	5	5
93	R:R:G112	R:R:W113	2.81	No	No	0	4	8
94	R:R:R117	R:R:W113	16.99	No	No	0	3	8
95	R:R:F115	R:R:L114	6.09	Yes	No	0	6	3
96	R:R:C120	R:R:F115	4.19	No	Yes	0	9	6
97	R:R:F185	R:R:R117	11.76	No	No	0	4	3
98	R:R:I118	R:R:K121	2.91	No	No	0	3	7
99	R:R:E182	R:R:S124	7.19	No	No	0	5	5
100	R:R:F125	R:R:M176	4.98	No	No	0	6	4
101	R:R:A179	R:R:F125	2.77	No	No	0	7	6
102	R:R:S175	R:R:T129	6.4	No	No	0	8	5
103	R:R:M176	R:R:T129	10.54	No	No	0	4	5
104	R:R:G132	R:R:V131	3.68	No	No	1	7	8
105	R:R:V131	R:R:W284	4.9	No	Yes	1	8	8
106	R:R:F136	R:R:G132	3.01	Yes	No	1	6	7
107	R:R:F225	R:R:G132	4.52	Yes	No	1	6	7
108	R:R:V133	R:R:V171	3.21	No	No	0	7	7
109	R:R:V133	R:R:W172	18.39	No	Yes	0	7	9
110	R:R:S175	R:R:V133	4.85	No	No	0	8	7
111	R:R:F136	R:R:V135	2.62	Yes	No	0	6	8
112	R:R:P229	R:R:V135	3.53	No	No	0	9	8
113	R:R:F280	R:R:V135	3.93	Yes	No	0	9	8
114	R:R:F136	R:R:V174	2.62	Yes	No	1	6	4
115	R:R:F136	R:R:F178	4.29	Yes	No	1	6	5
116	R:R:F136	R:R:V224	2.62	Yes	No	1	6	5
117	R:R:F136	R:R:F225	6.43	Yes	Yes	1	6	6
118	R:R:L138	R:R:N326	5.49	No	No	1	8	9
119	R:R:P229	R:R:T139	3.5	No	No	0	9	7
120	R:R:I232	R:R:T139	6.08	No	No	0	6	7
121	R:R:L141	R:R:R145	9.72	No	No	0	9	9
122	R:R:I233	R:R:S142	7.74	No	No	6	8	9
123	R:R:S142	R:R:Y236	5.09	No	No	0	9	7
124	R:R:S142	R:R:Y237	12.72	No	Yes	6	9	9
125	R:R:A143	R:R:Y236	4	No	No	0	6	7
126	R:R:R145	R:R:Y237	7.2	No	Yes	0	9	9
127	R:R:V150	R:R:Y146	13.88	No	Yes	0	7	8
128	R:R:K151	R:R:Y146	4.78	No	Yes	0	6	8
129	R:R:Y146	R:R:Y236	11.91	Yes	No	0	8	7
130	R:R:L239	R:R:Y146	8.21	No	Yes	0	5	8
131	R:R:I240	R:R:Y146	3.63	No	Yes	0	8	8
132	R:R:V149	R:R:V150	3.21	No	No	0	9	7
133	R:R:I240	R:R:V149	3.07	No	No	0	8	9
134	R:R:L244	R:R:V149	2.98	Yes	No	0	8	9
135	R:R:T243	R:R:V150	14.28	No	No	0	6	7
136	R:R:E154	R:R:K151	4.05	No	No	0	4	6
137	R:R:P157	R:R:Q156	3.16	No	No	0	3	4
138	R:R:A160	R:R:K163	4.82	No	No	0	7	4
139	R:R:C170	R:R:K167	3.23	No	No	0	3	6
140	R:R:G169	R:R:W172	2.81	No	Yes	0	4	9
141	R:R:F178	R:R:V174	2.62	No	No	1	5	4
142	R:R:F178	R:R:V224	3.93	No	No	1	5	5
143	R:R:E182	R:R:S205	2.87	No	No	0	5	4
144	R:R:I184	R:R:Y206	3.63	No	Yes	0	5	3
145	R:R:F185	R:R:P207	5.78	No	No	0	4	3
146	R:R:S205	R:R:Y206	13.99	No	Yes	0	4	3
147	R:R:K210	R:R:Y206	17.91	No	Yes	1	4	3
148	R:R:L213	R:R:Y206	8.21	No	Yes	1	4	3
149	R:R:Q214	R:R:Y206	5.64	Yes	Yes	1	3	3
150	R:R:H217	R:R:Y206	13.07	Yes	Yes	1	6	3
151	R:R:K210	R:R:L213	14.1	No	No	1	4	4
152	R:R:K210	R:R:Q214	14.92	No	Yes	1	4	3
153	R:R:I216	R:R:L212	2.85	No	No	0	5	1
154	R:R:Q214	R:R:Y291	4.51	Yes	Yes	1	3	6
155	R:R:Q214	R:R:S295	7.22	Yes	No	0	3	4
156	R:R:E215	R:R:L219	3.98	No	No	0	3	5
157	R:R:E215	R:R:S295	2.87	No	No	0	3	4
158	R:R:E215	R:R:F296	8.16	No	No	0	3	5
159	R:R:H217	R:R:Y291	8.71	Yes	Yes	1	6	6
160	R:R:S218	R:R:Y291	10.17	No	Yes	0	5	6
161	R:R:L292	R:R:S218	7.51	No	No	0	5	5
162	R:R:S218	R:R:S295	6.52	No	No	0	5	4
163	R:R:C221	R:R:F225	2.79	No	Yes	1	5	6
164	R:R:F222	R:R:Y226	5.16	Yes	Yes	1	6	8
165	R:R:F222	R:R:I227	6.28	Yes	No	0	6	4
166	R:R:F222	R:R:H288	5.66	Yes	Yes	1	6	7
167	R:R:F222	R:R:L292	3.65	Yes	No	0	6	5
168	R:R:I227	R:R:L223	4.28	No	No	0	4	5
169	R:R:F225	R:R:V224	2.62	Yes	No	1	6	5
170	R:R:L230	R:R:Y226	7.03	No	Yes	0	6	8
171	R:R:L285	R:R:Y226	8.21	No	Yes	0	6	8
172	R:R:H288	R:R:Y226	8.71	Yes	Yes	1	7	8
173	R:R:I228	R:R:P229	3.39	No	No	0	5	9
174	R:R:I228	R:R:I232	2.94	No	No	0	5	6
175	R:R:F280	R:R:L230	7.31	Yes	No	0	9	6
176	R:R:A281	R:R:L230	3.15	No	No	0	5	6
177	R:R:I233	R:R:Y237	7.25	No	Yes	6	8	9
178	R:R:S234	R:R:V277	3.23	No	No	0	4	8
179	R:R:V273	R:R:Y237	7.57	No	Yes	0	8	9
180	R:R:V277	R:R:Y237	3.79	No	Yes	0	8	9
181	R:R:A241	R:R:L274	3.15	No	No	0	5	5
182	R:R:K246	R:R:T243	3	No	No	0	4	6
183	R:R:L244	R:R:S247	3	Yes	No	3	8	7
184	R:R:L244	R:R:R266	3.64	Yes	Yes	3	8	7
185	R:R:I269	R:R:L244	2.85	No	Yes	0	7	8
186	R:R:K267	R:R:Y245	3.58	No	No	0	5	5
187	R:R:A270	R:R:Y245	6.67	No	No	0	7	5
188	R:R:R266	R:R:S247	5.27	Yes	No	3	7	7
189	R:R:I263	R:R:T248	6.08	Yes	No	0	3	4
190	R:R:I251	R:R:P252	3.39	Yes	No	0	4	4
191	R:R:I251	R:R:Q262	9.61	Yes	No	3	4	4
192	R:R:I251	R:R:I263	10.3	Yes	Yes	0	4	3
193	R:R:I251	R:R:R266	7.52	Yes	Yes	3	4	7
194	R:R:A259	R:R:P252	3.74	No	No	0	3	4
195	R:R:E254	R:R:T253	4.23	No	No	0	4	4
196	R:R:R260	R:R:T253	5.17	No	No	0	3	4
197	R:R:Q256	R:R:R260	4.67	No	No	0	1	3
198	R:R:Q262	R:R:R266	3.5	No	Yes	3	4	7
199	R:R:R268	R:R:S265	2.64	No	No	0	7	6
200	R:R:K267	R:R:R271	3.71	No	No	0	5	7
201	R:R:I269	R:R:L333	2.85	No	No	0	7	6
202	R:R:L276	R:R:T272	2.95	No	No	0	8	8
203	R:R:L333	R:R:T272	11.79	No	No	0	6	8
204	R:R:A329	R:R:L276	4.73	No	No	0	8	8
205	R:R:L279	R:R:V325	4.47	No	No	0	7	6
206	R:R:F280	R:R:W284	7.02	Yes	Yes	1	9	8
207	R:R:F280	R:R:N322	6.04	Yes	Yes	1	9	9
208	R:R:C283	R:R:S321	3.44	No	No	0	8	5
209	R:R:C283	R:R:N322	3.15	No	Yes	0	8	9
210	R:R:H288	R:R:W284	4.23	Yes	Yes	1	7	8
211	R:R:A319	R:R:W284	2.59	No	Yes	0	8	8
212	R:R:N322	R:R:W284	6.78	Yes	Yes	1	9	8
213	R:R:L285	R:R:P286	3.28	No	No	0	6	9
214	R:R:L285	R:R:L289	8.3	No	No	0	6	6
215	R:R:P286	R:R:S315	3.56	No	No	0	9	6
216	R:R:L318	R:R:P286	4.93	No	No	0	7	9
217	R:R:N287	R:R:S315	4.47	No	No	0	7	6
218	R:R:A319	R:R:N287	4.69	No	No	0	8	7
219	R:R:H294	R:R:L290	5.14	No	Yes	0	4	4
220	R:R:L290	R:R:T312	7.37	Yes	No	0	4	4
221	R:R:L290	R:R:S315	4.5	Yes	No	0	4	6
222	R:R:F296	R:R:L292	3.65	No	No	0	5	5
223	R:R:H294	R:R:H308	7.17	No	Yes	0	4	3
224	R:R:H308	R:R:T312	6.85	Yes	No	0	3	4
225	R:R:I313	R:R:V317	3.07	No	No	0	4	5
226	R:R:F314	R:R:L318	13.4	No	No	0	5	7
227	R:R:F320	R:R:R316	3.21	Yes	No	1	7	5
228	R:R:F320	R:R:V317	7.87	Yes	No	1	7	5
229	R:R:L318	R:R:S321	3	No	No	0	7	5
230	R:R:N322	R:R:N326	5.45	Yes	No	1	9	9
231	R:R:Q338	R:R:Y331	6.76	No	No	0	8	7
232	R:R:F341	R:R:Y331	11.35	Yes	No	0	6	7
233	R:R:F337	R:R:S334	2.64	No	No	0	9	8
234	R:R:H340	R:R:S336	4.18	Yes	No	0	5	6
235	R:R:K339	R:R:Q338	2.71	No	No	0	4	8
236	R:R:K342	R:R:Q338	4.07	No	No	0	5	8
237	R:R:F341	R:R:K342	3.72	Yes	No	0	6	5
238	R:R:F341	R:R:L345	6.09	Yes	No	0	6	6
239	R:R:E254	R:R:E255	2.54	No	No	0	4	1
240	R:R:I263	R:R:R260	2.51	Yes	No	0	3	3
241	R:R:F311	R:R:L290	2.44	No	Yes	0	5	4
242	R:R:T272	R:R:W332	2.43	No	No	0	8	6
243	R:R:D144	R:R:F85	2.39	No	Yes	0	8	8
244	R:R:F309	R:R:Y108	2.06	No	Yes	0	4	5
245	R:R:F337	R:R:Y331	2.06	No	No	0	9	7
246	R:R:R268	R:R:W332	2	No	No	0	7	6
247	R:R:G119	R:R:V122	1.84	No	No	0	5	4
248	R:R:A241	R:R:A270	1.79	No	No	0	5	7
249	R:R:G61	R:R:L97	1.71	No	No	0	8	6
250	R:R:A168	R:R:S88	1.71	No	No	0	8	9
251	R:R:K151	R:R:P152	1.67	No	No	0	6	8
252	R:R:C165	R:R:I84	1.64	No	No	0	4	5
253	R:R:C165	R:R:I161	1.64	No	No	0	4	3
254	R:R:L180	R:R:P181	1.64	No	No	0	4	7
255	R:R:S234	R:R:S238	1.63	No	No	0	4	4
256	R:R:S59	R:R:V60	1.62	No	Yes	0	5	6
257	R:R:S209	R:R:V208	1.62	No	No	0	4	5
258	R:R:V56	R:R:V60	1.6	No	Yes	0	5	6
259	R:R:C283	R:R:L279	1.59	No	No	0	8	7
260	R:R:A270	R:R:L244	1.58	No	Yes	0	7	8
261	R:R:I227	R:R:S231	1.55	No	No	0	4	4
262	R:R:I126	R:R:V122	1.54	No	No	0	5	4
263	R:R:H217	R:R:P181	1.53	Yes	No	0	6	7
264	R:R:I57	R:R:T53	1.52	No	No	0	8	5
265	R:R:F115	R:R:G116	1.51	Yes	No	0	6	8
266	R:R:F115	R:R:G119	1.51	Yes	No	0	6	5
267	R:R:L239	R:R:V235	1.49	No	No	0	5	4
268	R:R:L279	R:R:V275	1.49	No	No	0	7	6
269	R:R:I173	R:R:I177	1.47	No	No	0	3	4
270	R:R:I62	R:R:L63	1.43	No	No	0	6	4
271	R:R:I62	R:R:L94	1.43	No	No	0	6	7
272	R:R:I177	R:R:L180	1.43	No	No	0	4	4
273	R:R:P207	R:R:Y206	1.39	No	Yes	0	3	3
274	R:R:H308	R:R:S305	1.39	Yes	No	0	3	2
275	R:R:A241	R:R:R242	1.38	No	No	0	5	4
276	R:R:H107	R:R:T106	1.37	No	No	0	5	5
277	R:R:E264	R:R:I263	1.37	No	Yes	0	4	3
278	R:R:E154	R:R:K147	1.35	No	No	0	4	5
279	R:R:A55	R:R:Y51	1.33	No	No	0	6	5
280	R:R:E154	R:R:L153	1.33	No	No	0	4	6
281	R:R:R127	R:R:V103	1.31	No	No	0	6	5
282	R:R:H308	R:R:M307	1.31	Yes	No	0	3	3
283	R:R:K335	R:R:R268	1.24	No	No	0	5	7
284	R:R:I52	R:R:Y51	1.21	No	No	0	5	5
285	R:R:H294	R:R:Y293	1.09	No	No	0	4	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:?1	8.41769	13	1	0
2	R:R:Y54	8.304	5	1	7
3	R:R:V60	2.85	5	4	6
4	R:R:F72	8.285	4	0	7
5	R:R:M78	5.648	5	2	7
6	R:R:V81	4.19	4	5	6
7	R:R:F85	4.034	5	0	8
8	R:R:L89	6.695	4	1	9
9	R:R:C100	3.3225	4	1	6
10	R:R:Y108	5.055	4	0	5
11	R:R:F115	3.34667	6	0	6
12	R:R:F136	3.59833	6	1	6
13	R:R:Y146	8.482	5	0	8
14	R:R:W172	7.2375	4	0	9
15	R:R:Y206	9.12	7	1	3
16	R:R:Q214	8.0725	4	1	3
17	R:R:H217	6.5625	4	1	6
18	R:R:F222	5.1875	4	1	6
19	R:R:F225	4.016	5	1	6
20	R:R:Y226	7.2775	4	1	8
21	R:R:Y237	7.706	5	6	9
22	R:R:L244	2.81	5	3	8
23	R:R:I251	7.705	4	3	4
24	R:R:I263	5.065	4	0	3
25	R:R:R266	4.9825	4	3	7
26	R:R:F280	6.075	4	1	9
27	R:R:W284	5.12333	6	1	8
28	R:R:H288	7.84	4	1	7
29	R:R:L290	4.8625	4	0	4
30	R:R:Y291	8.085	4	1	6
31	R:R:H308	4.18	4	0	3
32	R:R:F320	5.57167	6	1	7
33	R:R:N322	5.355	4	1	9
34	R:R:H340	6.26	5	2	5
35	R:R:F341	6.545	4	0	6

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:C100	53.4748	3.63	Yes	Yes	1	0	6
2	R:R:C100	R:R:Y54	29.2155	2.69	Yes	Yes	1	6	7
3	R:R:D104	R:R:Y54	11.3643	20.69	No	Yes	0	6	7
4	L:L:?1	R:R:R316	25.0812	16.69	Yes	No	1	0	5
5	R:R:F320	R:R:R316	24.6186	3.21	Yes	No	1	7	5
6	R:R:I58	R:R:Y54	26.7497	4.84	No	Yes	1	7	7
7	R:R:C100	R:R:F320	24.4069	2.79	Yes	Yes	1	6	7
8	R:R:F320	R:R:I58	42.9422	7.54	Yes	No	1	7	7
9	R:R:I58	R:R:L97	67.7921	2.85	No	No	0	7	6
10	R:R:G61	R:R:L97	18.304	1.71	No	No	0	8	6
11	R:R:G61	R:R:V60	12.2207	3.68	No	Yes	4	8	6
12	R:R:D93	R:R:L97	55.3549	8.14	No	No	0	9	6
13	R:R:D93	R:R:N65	48.4644	16.16	No	No	0	9	9
14	R:R:L94	R:R:N65	45.0586	5.49	No	No	0	7	9
15	R:R:I62	R:R:L94	43.4049	1.43	No	No	0	6	7
16	R:R:I62	R:R:L63	41.825	1.43	No	No	0	6	4
17	R:R:G64	R:R:L63	40.3731	3.42	No	No	0	8	4
18	R:R:G64	R:R:I67	37.8433	3.53	No	No	0	8	7
19	R:R:F341	R:R:I67	36.6178	5.02	Yes	No	0	6	7
20	L:L:?1	R:R:W284	75.8146	5.22	Yes	Yes	1	0	8
21	R:R:N322	R:R:W284	87.5677	6.78	Yes	Yes	1	9	8
22	R:R:N322	R:R:N326	100	5.45	Yes	No	1	9	9
23	R:R:L89	R:R:N326	98.6662	13.73	Yes	No	1	9	9
24	R:R:L89	R:R:T137	98.7646	5.9	Yes	No	0	9	7
25	R:R:F85	R:R:T137	94.2219	5.19	Yes	No	0	8	7
26	R:R:F85	R:R:T164	92.263	2.59	Yes	No	0	8	7
27	R:R:T164	R:R:V81	90.4912	4.76	No	Yes	0	7	6
28	R:R:T80	R:R:V81	88.0746	3.17	No	Yes	5	8	6
29	R:R:N83	R:R:T80	88.2567	4.39	No	No	0	8	8
30	R:R:F72	R:R:N83	85.6039	4.83	Yes	No	0	7	8
31	R:R:F72	R:R:T87	82.4589	18.16	Yes	No	0	7	6
32	R:R:L68	R:R:T87	82.1636	2.95	No	No	0	9	6
33	R:R:I86	R:R:L68	97.2734	4.28	No	No	0	8	9
34	R:R:F341	R:R:Y331	29.8258	11.35	Yes	No	0	6	7
35	R:R:F337	R:R:Y331	28.1327	2.06	No	No	0	9	7
36	R:R:I86	R:R:L141	95.8657	4.28	No	No	0	8	9
37	R:R:S88	R:R:T137	20.0758	3.2	No	No	0	9	7
38	R:R:S88	R:R:W172	16.8274	4.94	No	Yes	0	9	9
39	L:L:?1	R:R:R127	27.5372	5.56	Yes	No	0	0	6
40	R:R:R127	R:R:T99	24.466	5.17	No	No	0	6	6
41	R:R:I126	R:R:T99	22.7581	3.04	No	No	0	5	6
42	R:R:I126	R:R:V122	19.3031	1.54	No	No	0	5	4
43	R:R:G119	R:R:V122	17.5657	1.84	No	No	0	5	4
44	R:R:F115	R:R:G119	15.8185	1.51	Yes	No	0	6	5
45	L:L:?1	R:R:S205	19.5541	4.58	Yes	No	0	0	4
46	R:R:S205	R:R:Y206	14.9178	13.99	No	Yes	0	4	3
47	R:R:P207	R:R:Y206	16.729	1.39	No	Yes	0	3	3
48	R:R:F185	R:R:P207	13.3379	5.78	No	No	0	4	3
49	L:L:?1	R:R:H217	22.4087	2.94	Yes	Yes	1	0	6
50	R:R:H217	R:R:Y206	14.9572	13.07	Yes	Yes	1	6	3
51	R:R:V133	R:R:W172	11.8811	18.39	No	Yes	0	7	9
52	L:L:?1	R:R:F225	12.6735	3.72	Yes	Yes	1	0	6
53	R:R:F280	R:R:V135	13.4265	3.93	Yes	No	0	9	8
54	R:R:P229	R:R:V135	12.89	3.53	No	No	0	9	8
55	R:R:L141	R:R:R145	95.1718	9.72	No	No	0	9	9
56	R:R:R145	R:R:Y237	94.468	7.2	No	Yes	0	9	9
57	R:R:S142	R:R:Y237	89.6496	12.72	No	Yes	6	9	9
58	R:R:S142	R:R:Y236	89.2657	5.09	No	No	0	9	7
59	R:R:Y146	R:R:Y236	87.6907	11.91	Yes	No	0	8	7
60	R:R:V150	R:R:Y146	41.5838	13.88	No	Yes	0	7	8
61	R:R:I240	R:R:Y146	39.4379	3.63	No	Yes	0	8	8
62	R:R:V149	R:R:V150	38.5569	3.21	No	No	0	9	7
63	R:R:I240	R:R:V149	38.3798	3.07	No	No	0	8	9
64	R:R:L244	R:R:V149	74.5989	2.98	Yes	No	0	8	9
65	L:L:?1	R:R:Y291	17.3491	8.95	Yes	Yes	1	0	6
66	R:R:F222	R:R:H288	11.2659	5.66	Yes	Yes	1	6	7
67	R:R:A270	R:R:L244	17.6445	1.58	No	Yes	0	7	8
68	R:R:L244	R:R:R266	32.5721	3.64	Yes	Yes	3	8	7
69	R:R:I251	R:R:R266	27.9014	7.52	Yes	Yes	3	4	7
70	R:R:I251	R:R:I263	20.4548	10.3	Yes	Yes	0	4	3
71	R:R:I263	R:R:R260	12.8654	2.51	Yes	No	0	3	3
72	R:R:I269	R:R:L244	22.453	2.85	No	Yes	0	7	8
73	R:R:I269	R:R:L333	20.2234	2.85	No	No	0	7	6
74	R:R:L333	R:R:T272	17.9348	11.79	No	No	0	6	8
75	R:R:T272	R:R:W332	10.3012	2.43	No	No	0	8	6
76	R:R:C283	R:R:N322	10.3357	3.15	No	Yes	0	8	9
77	R:R:A319	R:R:W284	11.1674	2.59	No	Yes	0	8	8
78	L:L:?1	R:R:N287	24.9631	23.06	Yes	No	0	0	7
79	R:R:A319	R:R:N287	10.375	4.69	No	No	0	8	7
80	R:R:N287	R:R:S315	31.2432	4.47	No	No	0	7	6
81	R:R:L290	R:R:S315	27.4486	4.5	Yes	No	0	4	6
82	R:R:H294	R:R:L290	12.5111	5.14	No	Yes	0	4	4
83	R:R:F337	R:R:L68	28.0244	7.31	No	No	0	9	9
84	R:R:F280	R:R:N322	11.6104	6.04	Yes	Yes	1	9	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?1	R:R:C100	3.63	1	Yes	Yes	0	6	0	1
L:L:?1	R:R:R127	5.56	1	Yes	No	0	6	0	1
L:L:?1	R:R:L128	9.51	1	Yes	No	0	5	0	1
L:L:?1	R:R:V131	7.96	1	Yes	No	0	8	0	1
L:L:?1	R:R:S205	4.58	1	Yes	No	0	4	0	1
L:L:?1	R:R:H217	2.94	1	Yes	Yes	0	6	0	1
L:L:?1	R:R:C221	4.85	1	Yes	No	0	5	0	1
L:L:?1	R:R:F225	3.72	1	Yes	Yes	0	6	0	1
L:L:?1	R:R:W284	5.22	1	Yes	Yes	0	8	0	1
L:L:?1	R:R:N287	23.06	1	Yes	No	0	7	0	1
L:L:?1	R:R:H288	12.76	1	Yes	Yes	0	7	0	1
L:L:?1	R:R:Y291	8.95	1	Yes	Yes	0	6	0	1
L:L:?1	R:R:R316	16.69	1	Yes	No	0	5	0	1
R:R:C100	R:R:Y54	2.69	1	Yes	Yes	6	7	1	2
R:R:F320	R:R:Y54	8.25	1	Yes	Yes	7	7	2	2
R:R:R127	R:R:T99	5.17	0	No	No	6	6	1	2
R:R:C100	R:R:R316	4.18	1	Yes	No	6	5	1	1
R:R:C100	R:R:F320	2.79	1	Yes	Yes	6	7	1	2
R:R:G132	R:R:V131	3.68	1	No	No	7	8	2	1
R:R:V131	R:R:W284	4.9	1	No	Yes	8	8	1	1
R:R:F136	R:R:G132	3.01	1	Yes	No	6	7	2	2
R:R:F225	R:R:G132	4.52	1	Yes	No	6	7	1	2
R:R:F136	R:R:V224	2.62	1	Yes	No	6	5	2	2
R:R:F136	R:R:F225	6.43	1	Yes	Yes	6	6	2	1
R:R:E182	R:R:S205	2.87	0	No	No	5	4	2	1
R:R:S205	R:R:Y206	13.99	0	No	Yes	4	3	1	2
R:R:Q214	R:R:Y206	5.64	1	Yes	Yes	3	3	2	2
R:R:H217	R:R:Y206	13.07	1	Yes	Yes	6	3	1	2
R:R:Q214	R:R:Y291	4.51	1	Yes	Yes	3	6	2	1
R:R:H217	R:R:Y291	8.71	1	Yes	Yes	6	6	1	1
R:R:S218	R:R:Y291	10.17	0	No	Yes	5	6	2	1
R:R:C221	R:R:F225	2.79	1	No	Yes	5	6	1	1
R:R:F222	R:R:Y226	5.16	1	Yes	Yes	6	8	2	2
R:R:F222	R:R:H288	5.66	1	Yes	Yes	6	7	2	1
R:R:F225	R:R:V224	2.62	1	Yes	No	6	5	1	2
R:R:H288	R:R:Y226	8.71	1	Yes	Yes	7	8	1	2
R:R:F280	R:R:W284	7.02	1	Yes	Yes	9	8	2	1
R:R:F280	R:R:N322	6.04	1	Yes	Yes	9	9	2	2
R:R:H288	R:R:W284	4.23	1	Yes	Yes	7	8	1	1
R:R:A319	R:R:W284	2.59	0	No	Yes	8	8	2	1
R:R:N322	R:R:W284	6.78	1	Yes	Yes	9	8	2	1
R:R:N287	R:R:S315	4.47	0	No	No	7	6	1	2
R:R:A319	R:R:N287	4.69	0	No	No	8	7	2	1
R:R:F320	R:R:R316	3.21	1	Yes	No	7	5	2	1
R:R:H217	R:R:P181	1.53	1	Yes	No	6	7	1	2
R:R:R127	R:R:V103	1.31	0	No	No	6	5	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	9K07_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	2.59
Number of Linked Nodes	247
Number of Links	285
Number of Hubs	35
Number of Links mediated by Hubs	144
Number of Communities	6
Number of Nodes involved in Communities	49
Number of Links involved in Communities	72

Path Summary
Number Of Nodes in MetaPath	85
Number Of Links MetaPath	84
Number of Shortest Paths	53408
Length Of Smallest Path	3
Average Path Length	16.761
Length of Longest Path	39
Minimum Path Strength	1.27
Average Path Strength	6.07045
Maximum Path Strength	19.875
Minimum Path Correlation	0.7
Average Path Correlation	0.927389
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	3.0303
Average % Of Corr. Nodes	46.0616
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	36.2284
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	_L_
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	_L_
Name
Synonyms
Identifier
Formula
Molecular Weight
SMILES
PubChem
Formal Charge
Total Atoms
Total Chiral Atoms
Total Bonds
Total Aromatic Bonds


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P32247
Sequence	>9K07_nogp_Chain_R C A I Y I T Y A V I I S V G I L G N A I L I K V F F K T K S M Q T V P N I F I T S L A F G D L L L L L T C V P V D A T H Y L A E G W L F G R I G C K V L S F I R L T S V G V S V F T L T I L S A D R Y K A V V K P L E R Q P S N A I L K T C V K A G C V W I V S M I F A L P E A I F T S Y P V S K K L L Q E I H S L L C F L V F Y I I P L S I I S V Y Y S L I A R T L Y K S T L N I P T E E Q S H A R K Q I E S R K R I A R T V L V L V A L F A L C W L P N H L L Y L Y H S F T S A M H F I F T I F S R V L A F S N S C V N P F A L Y W L S K S F Q K H F K A Q L Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8Y52	A	Peptide	Bombesin	BB₃	Homo sapiens	BA1	-	chim(NtGi1-Gs-CtGq)/β1/γ2	2.9	2024-09-11	doi.org/10.1016/j.celrep.2024.114511
	8Y52 (No Gprot)	A	Peptide	Bombesin	BB₃	Homo sapiens	BA1	-		2.9	2024-09-11	doi.org/10.1016/j.celrep.2024.114511
	8Y53	A	Peptide	Bombesin	BB₃	Homo sapiens	MK5046	-	chim(NtGi1-Gs-CtGq)/β1/γ2	2.93	2024-09-11	doi.org/10.1016/j.celrep.2024.114511
	8Y53 (No Gprot)	A	Peptide	Bombesin	BB₃	Homo sapiens	MK5046	-		2.93	2024-09-11	doi.org/10.1016/j.celrep.2024.114511
	8Y51	A	Peptide	Bombesin	BB₃	Homo sapiens	-	-	chim(NtGi1-Gs-CtGq)/β1/γ2	3.3	2025-02-12	To be published
	8Y51 (No Gprot)	A	Peptide	Bombesin	BB₃	Homo sapiens	-	-		3.3	2025-02-12	To be published
	9LWP	A	Peptide	Bombesin	BB₃	Homo sapiens	-	-	chim(NtGi2L-Gs-CtGq)/β1/γ2	2.93	2025-07-16	doi.org/10.1016/j.apsb.2025.06.025
	9LWP (No Gprot)	A	Peptide	Bombesin	BB₃	Homo sapiens	-	-		2.93	2025-07-16	doi.org/10.1016/j.apsb.2025.06.025
	9K07	A	Peptide	Bombesin	BB₃	Homo sapiens	DSO-5a	-	chim(NtGi2L-Gs-CtGq)/β1/γ2	2.87	2025-08-27	doi.org/10.1016/j.apsb.2025.06.025
	9K07 (No Gprot)	A	Peptide	Bombesin	BB₃	Homo sapiens	DSO-5a	-		2.87	2025-08-27	doi.org/10.1016/j.apsb.2025.06.025

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 9K07_nogp.zip

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