psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:D110	4.84	Yes	Yes	1	0	9
2	L:L:?1	R:R:Y111	15.05	Yes	Yes	1	0	9
3	L:L:?1	R:R:S114	9.64	Yes	No	0	0	9
4	L:L:?1	R:R:N115	6.86	Yes	Yes	1	0	9
5	L:L:?1	R:R:V118	5.31	Yes	Yes	1	0	9
6	L:L:?1	R:R:W162	5.69	Yes	Yes	1	0	8
7	L:L:?1	R:R:A201	5.62	Yes	No	0	0	9
8	L:L:?1	R:R:W455	17.06	Yes	Yes	1	0	9
9	L:L:?1	R:R:Y458	8.36	Yes	Yes	1	0	9
10	L:L:?1	R:R:N459	4.9	Yes	No	1	0	9
11	L:L:?1	R:R:Y481	14.22	Yes	Yes	1	0	9
12	L:L:?1	R:R:C484	5.66	Yes	No	1	0	9
13	L:L:?1	R:R:Y485	5.85	Yes	Yes	1	0	9
14	R:R:E29	R:R:R26	15.12	No	No	0	7	5
15	R:R:I31	R:R:L27	7.14	No	No	0	6	5
16	R:R:T37	R:R:T88	14.13	No	No	1	7	9
17	R:R:T37	R:R:W482	10.92	No	Yes	1	7	8
18	R:R:V40	R:R:W482	7.36	No	Yes	0	7	8
19	R:R:T489	R:R:V40	4.76	No	No	0	9	7
20	R:R:M84	R:R:S41	4.6	Yes	No	0	9	9
21	R:R:N85	R:R:S41	5.96	No	No	0	9	9
22	R:R:N48	R:R:T44	4.39	Yes	No	0	9	9
23	R:R:M84	R:R:T44	4.52	Yes	No	0	9	9
24	R:R:T44	R:R:T489	9.42	No	No	0	9	9
25	R:R:I45	R:R:L77	4.28	No	Yes	0	7	8
26	R:R:D76	R:R:N48	6.73	Yes	Yes	0	9	9
27	R:R:L77	R:R:N48	4.12	Yes	Yes	0	8	9
28	R:R:N48	R:R:P492	6.52	Yes	No	0	9	9
29	R:R:F506	R:R:L50	4.87	Yes	No	0	9	9
30	R:R:F506	R:R:V51	5.24	Yes	No	0	9	9
31	R:R:L77	R:R:M52	4.24	Yes	No	0	8	7
32	R:R:I53	R:R:L509	5.71	No	No	0	5	8
33	R:R:F502	R:R:S54	5.28	Yes	No	3	9	8
34	R:R:F506	R:R:S54	7.93	Yes	No	3	9	8
35	R:R:F55	R:R:K62	9.93	Yes	No	0	9	8
36	R:R:F55	R:R:Y67	5.16	Yes	No	0	9	8
37	R:R:F55	R:R:L70	19.49	Yes	No	0	9	8
38	R:R:L61	R:R:N58	8.24	No	No	0	9	8
39	R:R:N58	R:R:T505	5.85	No	No	0	8	9
40	R:R:K62	R:R:S59	7.65	No	No	0	8	8
41	R:R:L61	R:R:T501	8.84	No	No	0	9	8
42	R:R:F502	R:R:L61	13.4	Yes	No	0	9	9
43	R:R:N65	R:R:T63	10.24	No	No	3	9	8
44	R:R:N66	R:R:T63	8.77	Yes	No	3	9	8
45	R:R:N65	R:R:N66	6.81	No	Yes	3	9	9
46	R:R:N65	R:R:R142	12.05	No	Yes	3	9	9
47	R:R:F502	R:R:N66	7.25	Yes	Yes	3	9	9
48	R:R:V123	R:R:Y68	5.05	No	Yes	0	8	8
49	R:R:D127	R:R:Y68	8.05	No	Yes	0	9	8
50	R:R:A147	R:R:Y68	5.34	No	Yes	0	9	8
51	R:R:I151	R:R:Y68	4.84	No	Yes	0	9	8
52	R:R:N120	R:R:S71	8.94	No	No	2	9	9
53	R:R:I151	R:R:S71	9.29	No	No	0	9	9
54	R:R:S71	R:R:W155	6.18	No	Yes	2	9	9
55	R:R:D76	R:R:L72	8.14	Yes	Yes	2	9	9
56	R:R:L72	R:R:N120	4.12	Yes	No	2	9	9
57	R:R:L121	R:R:L72	5.54	Yes	Yes	2	9	9
58	R:R:L72	R:R:N491	5.49	Yes	Yes	2	9	9
59	R:R:D76	R:R:S117	5.89	Yes	No	0	9	9
60	R:R:D76	R:R:S488	7.36	Yes	No	0	9	9
61	R:R:D76	R:R:N491	10.77	Yes	Yes	2	9	9
62	R:R:I81	R:R:L77	7.14	No	Yes	0	5	8
63	R:R:I78	R:R:L109	4.28	No	No	0	8	6
64	R:R:I79	R:R:S114	4.64	No	No	0	9	9
65	R:R:I79	R:R:S488	10.84	No	No	0	9	9
66	R:R:G80	R:R:M84	5.24	No	Yes	0	9	9
67	R:R:F82	R:R:I81	11.3	No	No	0	6	5
68	R:R:D110	R:R:S83	11.78	Yes	No	0	9	9
69	R:R:M84	R:R:W482	4.65	Yes	Yes	1	9	8
70	R:R:M84	R:R:Y485	8.38	Yes	Yes	1	9	9
71	R:R:L86	R:R:W106	11.39	No	Yes	0	8	8
72	R:R:I91	R:R:Y87	13.3	No	Yes	1	8	8
73	R:R:W106	R:R:Y87	6.75	Yes	Yes	0	8	8
74	R:R:H478	R:R:Y87	5.44	No	Yes	1	6	8
75	R:R:Y481	R:R:Y87	21.84	Yes	Yes	1	9	8
76	R:R:Y485	R:R:Y87	6.95	Yes	Yes	1	9	8
77	R:R:T88	R:R:W482	4.85	No	Yes	1	9	8
78	R:R:W96	R:R:Y90	5.79	Yes	No	0	9	9
79	R:R:E182	R:R:Y90	5.61	No	No	0	5	9
80	R:R:H478	R:R:I91	10.61	No	No	1	6	8
81	R:R:A97	R:R:R95	6.91	No	No	0	6	4
82	R:R:L98	R:R:W96	10.25	No	Yes	0	8	9
83	R:R:C103	R:R:W96	7.84	No	Yes	4	9	9
84	R:R:W106	R:R:W96	13.12	Yes	Yes	0	8	9
85	R:R:C183	R:R:W96	13.06	No	Yes	4	9	9
86	R:R:R176	R:R:S100	5.27	Yes	No	0	8	5
87	R:R:C103	R:R:C183	7.28	No	No	4	9	9
88	R:R:D104	R:R:R176	10.72	No	Yes	0	8	8
89	R:R:L107	R:R:W106	5.69	No	Yes	0	9	8
90	R:R:D110	R:R:W106	5.58	Yes	Yes	0	9	8
91	R:R:C183	R:R:L107	4.76	No	No	0	9	9
92	R:R:I185	R:R:L107	8.56	Yes	No	0	9	9
93	R:R:A108	R:R:L167	4.73	No	No	0	8	7
94	R:R:D110	R:R:Y485	11.49	Yes	Yes	1	9	9
95	R:R:W162	R:R:Y111	13.5	Yes	Yes	1	8	9
96	R:R:I166	R:R:Y111	4.84	No	Yes	1	9	9
97	R:R:I185	R:R:Y111	14.51	Yes	Yes	1	9	9
98	R:R:Y111	R:R:Y458	5.96	Yes	Yes	1	9	9
99	R:R:Y111	R:R:Y481	6.95	Yes	Yes	1	9	9
100	R:R:M119	R:R:N115	7.01	No	Yes	0	8	9
101	R:R:N115	R:R:S158	8.94	Yes	No	0	9	9
102	R:R:L161	R:R:N115	4.12	No	Yes	1	9	9
103	R:R:N115	R:R:W162	7.91	Yes	Yes	1	9	8
104	R:R:A116	R:R:W155	9.08	No	Yes	0	9	9
105	R:R:F451	R:R:V118	5.24	Yes	Yes	1	9	9
106	R:R:V118	R:R:W455	4.9	Yes	Yes	1	9	9
107	R:R:N120	R:R:W155	5.65	No	Yes	2	9	9
108	R:R:L121	R:R:M209	4.24	Yes	No	0	9	9
109	R:R:L121	R:R:N491	9.61	Yes	Yes	2	9	9
110	R:R:L121	R:R:Y495	8.21	Yes	Yes	2	9	9
111	R:R:F126	R:R:L122	6.09	No	No	0	8	9
112	R:R:M150	R:R:V123	4.56	No	No	0	9	8
113	R:R:I124	R:R:R128	5.01	No	No	2	9	9
114	R:R:I124	R:R:Y495	4.84	No	Yes	2	9	9
115	R:R:S125	R:R:Y213	5.09	No	Yes	0	9	9
116	R:R:F126	R:R:L212	8.53	No	No	0	8	9
117	R:R:D127	R:R:Y138	8.05	No	No	3	9	9
118	R:R:D127	R:R:R142	13.1	No	Yes	3	9	9
119	R:R:R128	R:R:Y213	4.12	No	Yes	2	9	9
120	R:R:R128	R:R:Y495	7.2	No	Yes	2	9	9
121	R:R:F130	R:R:Y129	5.16	No	Yes	0	8	9
122	R:R:T133	R:R:Y129	11.24	No	Yes	0	9	9
123	R:R:L212	R:R:Y129	17.58	No	Yes	0	9	9
124	R:R:R215	R:R:Y129	11.32	No	Yes	0	7	9
125	R:R:F130	R:R:Y138	13.41	No	No	0	8	9
126	R:R:R142	R:R:S131	7.91	Yes	No	0	9	9
127	R:R:I132	R:R:I216	8.83	No	No	0	8	9
128	R:R:E219	R:R:T133	4.23	No	No	0	9	9
129	R:R:R142	R:R:Y138	11.32	Yes	No	3	9	9
130	R:R:I160	R:R:L156	5.71	No	No	0	5	5
131	R:R:A163	R:R:F159	6.93	No	No	0	8	6
132	R:R:L161	R:R:W162	10.25	No	Yes	1	9	8
133	R:R:T197	R:R:W162	6.06	No	Yes	0	9	8
134	R:R:A165	R:R:F187	4.16	No	Yes	0	9	9
135	R:R:I166	R:R:I185	5.89	No	Yes	1	9	9
136	R:R:L172	R:R:W169	4.56	No	No	0	5	9
137	R:R:V173	R:R:W169	7.36	No	No	0	7	9
138	R:R:F187	R:R:W169	7.02	Yes	No	0	9	9
139	R:R:Q170	R:R:Y171	12.4	No	No	0	8	7
140	R:R:Q170	R:R:R176	10.51	No	Yes	0	8	8
141	R:R:K175	R:R:V173	4.55	No	No	0	3	7
142	R:R:K175	R:R:T177	4.5	No	No	0	3	6
143	R:R:Q186	R:R:T177	9.92	No	No	0	9	6
144	R:R:Q186	R:R:V178	5.73	No	No	0	9	7
145	R:R:D181	R:R:P179	4.83	No	No	0	3	4
146	R:R:E182	R:R:P179	11	No	No	0	5	4
147	R:R:E182	R:R:Q184	5.1	No	No	0	5	5
148	R:R:F187	R:R:I185	7.54	Yes	Yes	0	9	9
149	R:R:I185	R:R:L188	8.56	Yes	No	0	9	7
150	R:R:F187	R:R:I193	10.05	Yes	No	0	9	8
151	R:R:L188	R:R:V462	4.47	No	No	0	7	9
152	R:R:E190	R:R:P191	6.29	No	No	0	7	7
153	R:R:E190	R:R:T192	4.23	No	No	0	7	7
154	R:R:F467	R:R:P191	4.33	No	No	0	8	7
155	R:R:I193	R:R:T197	4.56	No	No	0	8	9
156	R:R:T194	R:R:T466	4.71	No	No	0	9	8
157	R:R:F195	R:R:L463	9.74	No	No	0	8	8
158	R:R:F195	R:R:F467	7.5	No	No	0	8	8
159	R:R:I199	R:R:Y203	6.04	No	Yes	0	8	8
160	R:R:F202	R:R:Y203	9.28	Yes	Yes	0	9	8
161	R:R:F202	R:R:V206	9.18	Yes	Yes	1	9	8
162	R:R:F202	R:R:F451	5.36	Yes	Yes	1	9	9
163	R:R:F202	R:R:N459	21.75	Yes	No	1	9	9
164	R:R:L463	R:R:Y203	9.38	No	Yes	0	8	8
165	R:R:F451	R:R:V206	5.24	Yes	Yes	1	9	8
166	R:R:I211	R:R:R215	5.01	No	No	0	7	7
167	R:R:L444	R:R:Y213	5.86	No	Yes	0	9	9
168	R:R:L448	R:R:Y213	9.38	No	Yes	0	9	9
169	R:R:Y213	R:R:Y495	4.96	Yes	Yes	2	9	9
170	R:R:E221	R:R:Y217	15.71	No	No	0	7	8
171	R:R:E221	R:R:T220	4.23	No	No	0	7	9
172	R:R:D226	R:R:K222	11.06	No	No	0	6	6
173	R:R:D229	R:R:K225	16.59	No	No	0	6	8
174	R:R:L227	R:R:Q231	9.32	No	No	0	6	7
175	R:R:A441	R:R:Q442	4.55	No	No	0	9	7
176	R:R:I447	R:R:Y495	4.84	No	Yes	0	9	9
177	R:R:F451	R:R:W455	9.02	Yes	Yes	1	9	9
178	R:R:N487	R:R:T454	5.85	No	No	0	9	9
179	R:R:C484	R:R:W455	11.75	No	Yes	1	9	9
180	R:R:N487	R:R:W455	13.56	No	Yes	0	9	9
181	R:R:N459	R:R:Y458	4.65	No	Yes	1	9	9
182	R:R:M461	R:R:V472	7.61	Yes	No	0	7	8
183	R:R:L476	R:R:M461	4.24	No	Yes	0	6	7
184	R:R:F467	R:R:T466	7.78	No	No	0	8	8
185	R:R:C468	R:R:C471	7.28	No	No	5	8	8
186	R:R:D469	R:R:K470	9.68	No	No	0	4	3
187	R:R:L476	R:R:P473	9.85	No	No	0	6	7
188	R:R:H478	R:R:V474	4.15	No	No	0	6	1
189	R:R:Y481	R:R:Y485	5.96	Yes	Yes	1	9	9
190	R:R:W482	R:R:Y485	4.82	Yes	Yes	1	8	9
191	R:R:L483	R:R:V486	4.47	No	No	0	9	8
192	R:R:N487	R:R:N491	12.26	No	Yes	0	9	9
193	R:R:I493	R:R:L497	5.71	No	No	0	7	8
194	R:R:A496	R:R:F502	4.16	No	Yes	0	9	9
195	R:R:F506	R:R:L497	4.87	Yes	No	0	9	8
196	R:R:N499	R:R:T501	8.77	No	No	0	9	8
197	R:R:F502	R:R:N499	6.04	Yes	No	0	9	9
198	R:R:R500	R:R:R503	7.46	No	No	0	7	9
199	R:R:F502	R:R:F506	6.43	Yes	Yes	3	9	9
200	R:R:N58	R:R:Q60	3.96	No	No	0	8	7
201	R:R:R176	R:R:V178	3.92	Yes	No	0	8	7
202	R:R:W477	R:R:Y458	3.86	No	Yes	0	7	9
203	R:R:S465	R:R:W477	3.71	No	No	0	8	7
204	R:R:F82	R:R:L109	3.65	No	No	0	6	6
205	R:R:P205	R:R:V118	3.53	No	Yes	0	9	9
206	R:R:L444	R:R:Y217	3.52	No	No	0	9	8
207	R:R:P144	R:R:T143	3.5	No	No	0	7	9
208	R:R:P457	R:R:T456	3.5	No	No	0	9	9
209	R:R:M461	R:R:W477	3.49	Yes	No	0	7	7
210	R:R:A73	R:R:V51	3.39	No	No	0	9	9
211	R:R:I204	R:R:P205	3.39	No	No	0	7	9
212	R:R:A113	R:R:I78	3.25	No	No	0	8	8
213	R:R:A113	R:R:I79	3.25	No	No	0	8	9
214	R:R:C74	R:R:M52	3.24	No	No	0	7	7
215	R:R:A154	R:R:M119	3.22	No	No	0	9	8
216	R:R:V464	R:R:V472	3.21	Yes	No	0	7	8
217	R:R:T454	R:R:V486	3.17	No	No	0	9	8
218	R:R:A200	R:R:L161	3.15	No	No	0	9	9
219	R:R:I43	R:R:V39	3.07	No	No	0	6	5
220	R:R:I53	R:R:V49	3.07	No	No	0	5	7
221	R:R:I452	R:R:V206	3.07	No	Yes	0	8	8
222	R:R:I452	R:R:T456	3.04	No	No	0	8	9
223	R:R:K141	R:R:T137	3	No	No	0	8	7
224	R:R:K439	R:R:T443	3	No	No	0	9	9
225	R:R:L92	R:R:V30	2.98	Yes	No	0	6	7
226	R:R:L42	R:R:V46	2.98	No	No	0	7	6
227	R:R:L77	R:R:V49	2.98	Yes	No	0	8	7
228	R:R:L122	R:R:V208	2.98	No	No	0	9	8
229	R:R:L212	R:R:V208	2.98	No	No	0	9	8
230	R:R:L86	R:R:T89	2.95	No	No	0	8	7
231	R:R:L92	R:R:T88	2.95	Yes	No	0	6	9
232	R:R:I33	R:R:L92	2.85	No	Yes	0	9	6
233	R:R:I124	R:R:L69	2.85	No	No	0	9	9
234	R:R:I216	R:R:L444	2.85	No	No	0	9	9
235	R:R:L50	R:R:L510	2.77	No	No	0	9	8
236	R:R:C494	R:R:Y495	2.69	No	Yes	0	9	9
237	R:R:A198	R:R:Y203	2.67	No	Yes	0	9	8
238	R:R:A440	R:R:Y217	2.67	No	No	0	9	8
239	R:R:R142	R:R:V64	2.62	Yes	No	0	9	9
240	R:R:A75	R:R:W155	2.59	No	Yes	0	9	9
241	R:R:R146	R:R:T143	2.59	No	No	0	9	9
242	R:R:F55	R:R:N66	2.42	Yes	Yes	0	9	9
243	R:R:A147	R:R:G148	1.95	No	No	0	9	5
244	R:R:A163	R:R:P164	1.87	No	No	0	8	9
245	R:R:G47	R:R:V46	1.84	No	No	0	9	6
246	R:R:G174	R:R:V173	1.84	No	No	0	7	7
247	R:R:A450	R:R:C494	1.81	No	No	0	8	9
248	R:R:P144	R:R:V64	1.77	No	No	0	7	9
249	R:R:G480	R:R:M461	1.75	No	Yes	0	8	7
250	R:R:G47	R:R:L50	1.71	No	No	0	9	9
251	R:R:C468	R:R:V464	1.71	No	Yes	5	8	7
252	R:R:C471	R:R:V464	1.71	No	Yes	5	8	7
253	R:R:A163	R:R:V112	1.7	No	No	0	8	9
254	R:R:A450	R:R:V490	1.7	No	No	0	8	7
255	R:R:C214	R:R:T210	1.69	No	No	0	4	6
256	R:R:C498	R:R:T443	1.69	No	No	0	9	9
257	R:R:A108	R:R:I166	1.62	No	No	0	8	9
258	R:R:T505	R:R:V57	1.59	No	No	0	9	8
259	R:R:C168	R:R:L167	1.59	No	No	0	8	7
260	R:R:T210	R:R:V206	1.59	No	Yes	0	6	8
261	R:R:A34	R:R:L92	1.58	No	Yes	0	7	6
262	R:R:A102	R:R:L98	1.58	No	No	0	8	8
263	R:R:I460	R:R:V464	1.54	No	Yes	0	8	7
264	R:R:I43	R:R:T489	1.52	No	No	0	6	9
265	R:R:I447	R:R:T443	1.52	No	No	0	9	9
266	R:R:I453	R:R:T454	1.52	No	No	0	5	9
267	R:R:F195	R:R:G196	1.51	No	No	0	8	7
268	R:R:M508	R:R:T505	1.51	No	No	0	7	9
269	R:R:L180	R:R:S100	1.5	No	No	0	3	5
270	R:R:K145	R:R:T143	1.5	No	No	0	5	9
271	R:R:L27	R:R:V30	1.49	No	No	0	5	7
272	R:R:P135	R:R:R134	1.44	No	No	0	9	8
273	R:R:I157	R:R:L153	1.43	No	No	0	6	5
274	R:R:L101	R:R:L105	1.38	No	No	0	5	8
275	R:R:L105	R:R:L167	1.38	No	No	0	8	7
276	R:R:D226	R:R:K225	1.38	No	No	0	6	8
277	R:R:K439	R:R:Q442	1.36	No	No	0	9	7
278	R:R:E219	R:R:K222	1.35	No	No	0	9	6
279	R:R:R134	R:R:T133	1.29	No	No	0	8	9
280	R:R:R134	R:R:T137	1.29	No	No	0	8	7
281	R:R:R223	R:R:T224	1.29	No	No	0	9	7
282	R:R:K439	R:R:R438	1.24	No	No	0	9	7
283	R:R:V112	R:R:W162	1.23	No	Yes	0	9	8
284	R:R:L136	R:R:R139	1.21	No	No	0	9	8
285	R:R:D181	R:R:R95	1.19	No	No	0	3	4
286	R:R:L27	R:R:W28	1.14	No	No	0	5	4

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:?1	8.38923	13	1	0
2	R:R:N48	5.44	4	0	9
3	R:R:F55	9.25	4	0	9
4	R:R:N66	6.3125	4	3	9
5	R:R:Y68	5.82	4	0	8
6	R:R:L72	5.8225	4	2	9
7	R:R:D76	7.778	5	2	9
8	R:R:L77	4.552	5	0	8
9	R:R:M84	5.478	5	1	9
10	R:R:Y87	10.856	5	1	8
11	R:R:L92	2.59	4	0	6
12	R:R:W96	10.012	5	4	9
13	R:R:W106	8.506	5	0	8
14	R:R:D110	8.4225	4	1	9
15	R:R:Y111	10.135	6	1	9
16	R:R:N115	6.968	5	1	9
17	R:R:V118	4.745	4	1	9
18	R:R:L121	6.9	4	2	9
19	R:R:Y129	11.325	4	0	9
20	R:R:R142	9.4	5	3	9
21	R:R:W155	5.875	4	2	9
22	R:R:W162	7.44	6	1	8
23	R:R:R176	7.605	4	0	8
24	R:R:I185	9.012	5	1	9
25	R:R:F187	7.1925	4	0	9
26	R:R:F202	11.3925	4	1	9
27	R:R:Y203	6.8425	4	0	8
28	R:R:V206	4.77	4	1	8
29	R:R:Y213	5.882	5	2	9
30	R:R:F451	6.215	4	1	9
31	R:R:W455	11.258	5	1	9
32	R:R:Y458	5.7075	4	1	9
33	R:R:M461	4.2725	4	0	7
34	R:R:V464	2.0425	4	5	7
35	R:R:Y481	12.2425	4	1	9
36	R:R:W482	6.52	5	1	8
37	R:R:Y485	7.24167	6	1	9
38	R:R:N491	9.5325	4	2	9
39	R:R:Y495	5.45667	6	2	9
40	R:R:F502	7.09333	6	3	9
41	R:R:F506	5.868	5	3	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:Y485	31.3278	5.85	Yes	Yes	1	0	9
2	R:R:W482	R:R:Y485	19.7665	4.82	Yes	Yes	1	8	9
3	R:R:T88	R:R:W482	20.6094	4.85	No	Yes	1	9	8
4	R:R:L92	R:R:T88	18.1966	2.95	Yes	No	0	6	9
5	R:R:L92	R:R:V30	10.6488	2.98	Yes	No	0	6	7
6	R:R:M84	R:R:Y485	24.7313	8.38	Yes	Yes	1	9	9
7	R:R:M84	R:R:T44	34.2742	4.52	Yes	No	0	9	9
8	R:R:N48	R:R:T44	34.6454	4.39	Yes	No	0	9	9
9	R:R:L77	R:R:N48	22.3571	4.12	Yes	Yes	0	8	9
10	L:L:?1	R:R:W455	78.3543	17.06	Yes	Yes	1	0	9
11	R:R:N487	R:R:W455	93.8829	13.56	No	Yes	0	9	9
12	R:R:N487	R:R:N491	93.4189	12.26	No	Yes	0	9	9
13	R:R:D76	R:R:N491	12.5512	10.77	Yes	Yes	2	9	9
14	R:R:L72	R:R:N491	63.2124	5.49	Yes	Yes	2	9	9
15	R:R:L72	R:R:N120	100	4.12	Yes	No	2	9	9
16	R:R:N120	R:R:S71	94.6562	8.94	No	No	2	9	9
17	R:R:I151	R:R:S71	95.1667	9.29	No	No	0	9	9
18	R:R:I151	R:R:Y68	94.1536	4.84	No	Yes	0	9	8
19	R:R:D127	R:R:Y68	88.833	8.05	No	Yes	0	9	8
20	R:R:D127	R:R:R142	57.0258	13.1	No	Yes	3	9	9
21	R:R:N65	R:R:R142	52.3548	12.05	No	Yes	3	9	9
22	R:R:N65	R:R:N66	49.0681	6.81	No	Yes	3	9	9
23	R:R:F502	R:R:N66	39.618	7.25	Yes	Yes	3	9	9
24	R:R:F502	R:R:F506	18.7689	6.43	Yes	Yes	3	9	9
25	R:R:F502	R:R:L61	13.5179	13.4	Yes	No	0	9	9
26	R:R:L121	R:R:N491	33.1452	9.61	Yes	Yes	2	9	9
27	L:L:?1	R:R:D110	26.1233	4.84	Yes	Yes	1	0	9
28	R:R:D110	R:R:W106	28.1881	5.58	Yes	Yes	0	9	8
29	R:R:Y485	R:R:Y87	13.1776	6.95	Yes	Yes	1	9	8
30	R:R:W106	R:R:W96	26.2547	13.12	Yes	Yes	0	8	9
31	R:R:W96	R:R:Y90	17.5856	5.79	Yes	No	0	9	9
32	R:R:E182	R:R:Y90	15.1187	5.61	No	No	0	5	9
33	R:R:E182	R:R:P179	10.1384	11	No	No	0	5	4
34	L:L:?1	R:R:Y111	40.7393	15.05	Yes	Yes	1	0	9
35	R:R:I185	R:R:Y111	43.33	14.51	Yes	Yes	1	9	9
36	R:R:F187	R:R:I185	39.2236	7.54	Yes	Yes	0	9	9
37	R:R:F187	R:R:W169	35.4574	7.02	Yes	No	0	9	9
38	R:R:V173	R:R:W169	30.5235	7.36	No	No	0	7	9
39	R:R:K175	R:R:V173	25.5278	4.55	No	No	0	3	7
40	R:R:K175	R:R:T177	23.0067	4.5	No	No	0	3	6
41	R:R:Q186	R:R:T177	20.4702	9.92	No	No	0	9	6
42	R:R:Q186	R:R:V178	17.9182	5.73	No	No	0	9	7
43	R:R:R176	R:R:V178	15.3507	3.92	Yes	No	0	8	7
44	R:R:I166	R:R:Y111	12.4043	4.84	No	Yes	1	9	9
45	R:R:A108	R:R:I166	12.2496	1.62	No	No	0	8	9
46	R:R:A108	R:R:L167	10.0147	4.73	No	No	0	8	7
47	L:L:?1	R:R:N115	11.3448	6.86	Yes	Yes	1	0	9
48	L:L:?1	R:R:W162	15.1419	5.69	Yes	Yes	1	0	8
49	R:R:F451	R:R:W455	23.6409	9.02	Yes	Yes	1	9	9
50	R:R:L121	R:R:Y495	50.986	8.21	Yes	Yes	2	9	9
51	R:R:D127	R:R:Y138	30.8948	8.05	No	No	3	9	9
52	R:R:F130	R:R:Y138	34.8852	13.41	No	No	0	8	9
53	R:R:F130	R:R:Y129	33.1761	5.16	No	Yes	0	8	9
54	R:R:Y213	R:R:Y495	21.9859	4.96	Yes	Yes	2	9	9
55	R:R:T133	R:R:Y129	18.9467	11.24	No	Yes	0	9	9
56	R:R:L444	R:R:Y213	15.8456	5.86	No	Yes	0	9	9
57	L:L:?1	R:R:N459	17.9646	4.9	Yes	No	1	0	9
58	R:R:F202	R:R:N459	22.3571	21.75	Yes	No	1	9	9
59	R:R:F202	R:R:Y203	26.0923	9.28	Yes	Yes	0	9	8
60	R:R:L463	R:R:Y203	19.7587	9.38	No	Yes	0	8	8
61	R:R:F195	R:R:L463	17.6862	9.74	No	No	0	8	8
62	R:R:F195	R:R:F467	13.3555	7.5	No	No	0	8	8
63	R:R:F451	R:R:V206	15.2115	5.24	Yes	Yes	1	9	8
64	R:R:I447	R:R:Y495	15.9771	4.84	No	Yes	0	9	9
65	R:R:I447	R:R:T443	13.7654	1.52	No	No	0	9	9
66	L:L:?1	R:R:Y458	17.9259	8.36	Yes	Yes	1	0	9
67	R:R:W477	R:R:Y458	21.955	3.86	No	Yes	0	7	9
68	R:R:M461	R:R:W477	18.2971	3.49	Yes	No	0	7	7
69	R:R:M461	R:R:V472	10.3163	7.61	Yes	No	0	7	8
70	R:R:I452	R:R:V206	11.3139	3.07	No	Yes	0	8	8
71	R:R:D76	R:R:N48	36.1148	6.73	Yes	Yes	0	9	9
72	R:R:D76	R:R:L72	31.3974	8.14	Yes	Yes	2	9	9
73	R:R:L121	R:R:L72	21.7462	5.54	Yes	Yes	2	9	9
74	R:R:F202	R:R:F451	12.0872	5.36	Yes	Yes	1	9	9
75	R:R:M84	R:R:W482	10.7494	4.65	Yes	Yes	1	9	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?1	R:R:D110	4.84	1	Yes	Yes	0	9	0	1
L:L:?1	R:R:Y111	15.05	1	Yes	Yes	0	9	0	1
L:L:?1	R:R:S114	9.64	1	Yes	No	0	9	0	1
L:L:?1	R:R:N115	6.86	1	Yes	Yes	0	9	0	1
L:L:?1	R:R:V118	5.31	1	Yes	Yes	0	9	0	1
L:L:?1	R:R:W162	5.69	1	Yes	Yes	0	8	0	1
L:L:?1	R:R:A201	5.62	1	Yes	No	0	9	0	1
L:L:?1	R:R:W455	17.06	1	Yes	Yes	0	9	0	1
L:L:?1	R:R:Y458	8.36	1	Yes	Yes	0	9	0	1
L:L:?1	R:R:N459	4.9	1	Yes	No	0	9	0	1
L:L:?1	R:R:Y481	14.22	1	Yes	Yes	0	9	0	1
L:L:?1	R:R:C484	5.66	1	Yes	No	0	9	0	1
L:L:?1	R:R:Y485	5.85	1	Yes	Yes	0	9	0	1
R:R:I79	R:R:S114	4.64	0	No	No	9	9	2	1
R:R:D110	R:R:S83	11.78	1	Yes	No	9	9	1	2
R:R:M84	R:R:W482	4.65	1	Yes	Yes	9	8	2	2
R:R:M84	R:R:Y485	8.38	1	Yes	Yes	9	9	2	1
R:R:W106	R:R:Y87	6.75	0	Yes	Yes	8	8	2	2
R:R:Y481	R:R:Y87	21.84	1	Yes	Yes	9	8	1	2
R:R:Y485	R:R:Y87	6.95	1	Yes	Yes	9	8	1	2
R:R:D110	R:R:W106	5.58	1	Yes	Yes	9	8	1	2
R:R:D110	R:R:Y485	11.49	1	Yes	Yes	9	9	1	1
R:R:W162	R:R:Y111	13.5	1	Yes	Yes	8	9	1	1
R:R:I166	R:R:Y111	4.84	1	No	Yes	9	9	2	1
R:R:I185	R:R:Y111	14.51	1	Yes	Yes	9	9	2	1
R:R:Y111	R:R:Y458	5.96	1	Yes	Yes	9	9	1	1
R:R:Y111	R:R:Y481	6.95	1	Yes	Yes	9	9	1	1
R:R:M119	R:R:N115	7.01	0	No	Yes	8	9	2	1
R:R:N115	R:R:S158	8.94	1	Yes	No	9	9	1	2
R:R:L161	R:R:N115	4.12	1	No	Yes	9	9	2	1
R:R:N115	R:R:W162	7.91	1	Yes	Yes	9	8	1	1
R:R:F451	R:R:V118	5.24	1	Yes	Yes	9	9	2	1
R:R:V118	R:R:W455	4.9	1	Yes	Yes	9	9	1	1
R:R:L161	R:R:W162	10.25	1	No	Yes	9	8	2	1
R:R:T197	R:R:W162	6.06	0	No	Yes	9	8	2	1
R:R:I166	R:R:I185	5.89	1	No	Yes	9	9	2	2
R:R:F202	R:R:F451	5.36	1	Yes	Yes	9	9	2	2
R:R:F202	R:R:N459	21.75	1	Yes	No	9	9	2	1
R:R:F451	R:R:W455	9.02	1	Yes	Yes	9	9	2	1
R:R:C484	R:R:W455	11.75	1	No	Yes	9	9	1	1
R:R:N487	R:R:W455	13.56	0	No	Yes	9	9	2	1
R:R:N459	R:R:Y458	4.65	1	No	Yes	9	9	1	1
R:R:Y481	R:R:Y485	5.96	1	Yes	Yes	9	9	1	1
R:R:W482	R:R:Y485	4.82	1	Yes	Yes	8	9	2	1
R:R:W477	R:R:Y458	3.86	0	No	Yes	7	9	2	1
R:R:P205	R:R:V118	3.53	0	No	Yes	9	9	2	1
R:R:V112	R:R:W162	1.23	0	No	Yes	9	8	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	9EK0_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	4.11
Number of Linked Nodes	257
Number of Links	286
Number of Hubs	41
Number of Links mediated by Hubs	152
Number of Communities	5
Number of Nodes involved in Communities	51
Number of Links involved in Communities	74

Path Summary
Number Of Nodes in MetaPath	76
Number Of Links MetaPath	75
Number of Shortest Paths	37132
Length Of Smallest Path	3
Average Path Length	12.0726
Length of Longest Path	31
Minimum Path Strength	1.29
Average Path Strength	7.49182
Maximum Path Strength	18.03
Minimum Path Correlation	0.7
Average Path Correlation	0.926496
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	3.84615
Average % Of Corr. Nodes	54.9717
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	49.7643
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• phosphoric ester hydrolase activity • phospholipase activity • hydrolase activity, acting on ester bonds • phosphoric diester hydrolase activity • glycerophospholipase activity • hydrolase activity • C-type glycerophospholipase activity • phosphatidylinositol-4,5-bisphosphate phospholipase C activity • catalytic activity • lipase activity • neurotransmitter receptor activity • G protein-coupled amine receptor activity • G protein-coupled acetylcholine receptor activity • postsynaptic neurotransmitter receptor activity • molecular transducer activity • G protein-coupled receptor activity • signaling receptor activity • transmembrane signaling receptor activity • G protein-coupled neurotransmitter receptor activity • acetylcholine receptor activity • localization • multicellular organismal process • system process • digestion • secretion • transport • digestive system process • acid secretion • gastric acid secretion • establishment of localization • cellular response to stimulus • cellular response to nitrogen compound • regulation of cellular process • response to stimulus
Gene Ontology	Biological Process	• localization • multicellular organismal process • system process • digestion • secretion • transport • digestive system process • acid secretion • gastric acid secretion • establishment of localization • cellular response to stimulus • cellular response to nitrogen compound • regulation of cellular process • response to stimulus • signaling • cell communication • synaptic signaling • signal transduction • cellular response to acetylcholine • regulation of biological process • biological regulation • response to oxygen-containing compound • cell-cell signaling • response to nitrogen compound • acetylcholine receptor signaling pathway • postsynaptic signal transduction • cellular response to oxygen-containing compound • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • cellular response to chemical stimulus • G protein-coupled acetylcholine receptor signaling pathway • response to chemical • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • response to acetylcholine • G protein-coupled receptor signaling pathway • cellular process • adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway • nervous system process • transmission of nerve impulse • trans-synaptic signaling • anterograde trans-synaptic signaling • chemical synaptic transmission • monoamine transport • nitrogen compound transport • catecholamine transport • organic hydroxy compound transport • dopamine transport • regulation of lipid metabolic process • glycerophospholipid metabolic process • regulation of primary metabolic process • phospholipid metabolic process • phosphate-containing compound metabolic process • phosphorus metabolic process • phosphatidylinositol metabolic process • regulation of dephosphorylation • dephosphorylation • regulation of phospholipid metabolic process • primary metabolic process • lipid modification • regulation of macromolecule metabolic process • regulation of phosphatidylinositol dephosphorylation • organophosphate metabolic process • phosphatidylinositol dephosphorylation • phospholipid dephosphorylation • metabolic process • regulation of phosphorus metabolic process • glycerolipid metabolic process • macromolecule metabolic process • regulation of metabolic process • lipid metabolic process • G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger • cell periphery • postsynapse • cellular anatomical structure • postsynaptic membrane • synapse • cell junction • membrane • plasma membrane • plasma membrane region • synaptic membrane • somatodendritic compartment • cell projection • dendrite • dendritic tree
Gene Ontology	Cellular Component	• cell periphery • postsynapse • cellular anatomical structure • postsynaptic membrane • synapse • cell junction • membrane • plasma membrane • plasma membrane region • synaptic membrane • somatodendritic compartment • cell projection • dendrite • dendritic tree • neuron projection • plasma membrane bounded cell projection • cytoskeletal protein binding • spectrin binding • protein-containing complex binding • protein binding • binding • enzyme binding • GTPase binding • phosphoric ester hydrolase activity • alkylglycerophosphoethanolamine phosphodiesterase activity • hydrolase activity, acting on ester bonds • phosphoric diester hydrolase activity • hydrolase activity • catalytic activity • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity, acting on acid anhydrides • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • positive regulation of cytosolic calcium ion concentration • biological regulation • regulation of biological quality • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • response to decreased oxygen levels • cellular response to stimulus • response to stimulus • cellular response to oxygen levels • cellular response to hypoxia • cellular response to decreased oxygen levels • cellular response to chemical stimulus • cellular response to stress • response to hypoxia • response to stress • response to chemical • response to oxygen levels • response to abiotic stimulus • cellular process • cell population proliferation • regulation of biological process • regulation of cellular process • signaling • phospholipase C-activating G protein-coupled receptor signaling pathway • cell communication • G protein-coupled receptor signaling pathway • signal transduction • muscle cell apoptotic process • striated muscle cell apoptotic process • apoptotic process • cell death • programmed cell death • cardiac muscle cell apoptotic process • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • photoreceptor inner segment • intracellular anatomical structure • cytoplasm • membrane-bounded organelle • non-motile cilium • 9+0 non-motile cilium • cilium • photoreceptor outer segment • photoreceptor cell cilium • organelle • ciliary membrane • photoreceptor outer segment membrane • bounding membrane of organelle • organelle membrane • cell projection membrane • cell body • G-protein beta-subunit binding • fibroblast proliferation • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to oxygen-containing compound • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to oxygen-containing compound • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • response to hormone • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular region • extracellular space • vesicle • extracellular membrane-bounded organelle
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	IXO
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	IXO
Name	4-(4,5-dihydro-1,2-oxazol-3-yloxy)-N,N,N-trimethylbut-2-yn-1-aminium
Synonyms	Iperoxo
Identifier
Formula	C10 H17 N2 O2
Molecular Weight	197.254
SMILES
PubChem	10104167
Formal Charge	1
Total Atoms	31
Total Chiral Atoms	0
Total Bonds	31
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P08912
Sequence	>9EK0_nogp_Chain_R R L W E V I T I A A V T A V V S L I T I V G N V L V M I S F K V N S Q L K T V N N Y Y L L S L A C A D L I I G I F S M N L Y T T Y I L M G R W A L G S L A C D L W L A L D Y V A S N A S V M N L L V I S F D R Y F S I T R P L T Y R A K R T P K R A G I M I G L A W L I S F I L W A P A I L C W Q Y L V G K R T V P L D E C Q I Q F L S E P T I T F G T A I A A F Y I P V S V M T I L Y C R I Y R E T E K R T K D L A D L Q R K A A Q T L S A I L L A F I I T W T P Y N I M V L V S T F C D K C V P V T L W H L G Y W L C Y V N S T V N P I C Y A L C N R T F R K T F K M L L L C Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	6OL9	A	Amine	Acetylcholine (muscarinic)	M₅	Homo sapiens	Tiotropium	-	-	2.54	2019-12-11	doi.org/10.1073/pnas.1914446116
	7EPE	C	Aminoacid	Metabotropic Glutamate	mGlu₂	Homo sapiens	-	NAM563	-	2.5	2021-06-23	doi.org/10.1038/s41586-021-03641-w
	7EPF	C	Aminoacid	Metabotropic Glutamate	mGlu₂	Homo sapiens	-	NAM597	-	2.7	2021-06-23	doi.org/10.1038/s41586-021-03641-w
	7RM5	A	Nucleotide	Adenosine	A_2A	Homo sapiens	ZM-241385	Na	-	2.79	2021-09-08	doi.org/10.1073/pnas.2106041118
	7UM5	A	Amine	5-Hydroxytryptamine	5-HT_5A	Homo sapiens	5-CT	-	chim(NtGi1-Go)/β1/γ2	2.73	2022-07-20	doi.org/10.1038/s41594-022-00796-6
	7UM5 (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_5A	Homo sapiens	5-CT	-		2.73	2022-07-20	doi.org/10.1038/s41594-022-00796-6
	8JD0	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu3	Homo sapiens	Glutamate	NAM563	-	3.3	2023-06-21	doi.org/10.1038/s41422-023-00830-2
	9EK0	A	Amine	Acetylcholine (muscarinic)	M₅	Homo sapiens	Iperoxo	-	chim(NtGi1-Gs-CtGq)/β1/γ2	2.79	2025-10-08	doi.org/10.1038/s41467-025-62212-z
	9EK0 (No Gprot)	A	Amine	Acetylcholine (muscarinic)	M₅	Homo sapiens	Iperoxo	-		2.79	2025-10-08	doi.org/10.1038/s41467-025-62212-z
	9M54	A	Peptide	Neuropeptide FF	NPFF2	Homo sapiens	Neuropeptide-VF	-	Gi1/β1/γ2	3.24	2025-07-23	doi.org/10.1016/j.celrep.2025.116160
	9M54 (No Gprot)	A	Peptide	Neuropeptide FF	NPFF2	Homo sapiens	Neuropeptide-VF	-		3.24	2025-07-23	doi.org/10.1016/j.celrep.2025.116160
	9M55	A	Amine	Adrenergic	Oct-Beta2	Ixodes scapularis	DPMF	-	chim(NtGi1-Gs)/β1/γ2	3.39	2025-12-17	10.1093/pnasnexus/pgaf376
	9M55 (No Gprot)	A	Amine	Adrenergic	Oct-Beta2	Ixodes scapularis	DPMF	-		3.39	2025-12-17	10.1093/pnasnexus/pgaf376
	9M57	A	Amine	Adrenergic	Oct-Beta2	Ixodes scapularis	Octopamine	-	chim(NtGi1-Gs)/β1/γ2	3.65	2025-12-17	10.1093/pnasnexus/pgaf376
	9M57 (No Gprot)	A	Amine	Adrenergic	Oct-Beta2	Ixodes scapularis	Octopamine	-		3.65	2025-12-17	10.1093/pnasnexus/pgaf376

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