psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:I2	R:R:P3	3.39	Yes	No	3	6	6
2	R:R:I2	R:R:L6	4.28	Yes	No	3	6	5
3	R:R:I2	R:R:T7	3.04	Yes	No	0	6	4
4	R:R:I2	R:R:W257	9.4	Yes	Yes	0	6	3
5	R:R:L6	R:R:P3	6.57	No	No	3	5	6
6	R:R:I4	R:R:T7	4.56	No	No	0	4	4
7	R:R:F10	R:R:L6	7.31	No	No	0	5	5
8	R:R:F9	R:R:I13	12.56	No	No	0	5	7
9	R:R:F10	R:R:V260	7.87	No	No	0	5	4
10	R:R:F68	R:R:M11	6.22	No	Yes	1	3	4
11	R:R:F72	R:R:M11	9.95	Yes	Yes	1	3	4
12	R:R:M11	R:R:W259	22.1	Yes	Yes	1	4	3
13	R:R:E17	R:R:I13	4.1	No	No	0	8	7
14	R:R:S18	R:R:Y14	5.09	No	Yes	1	6	4
15	R:R:Q60	R:R:Y14	4.51	Yes	Yes	1	7	4
16	R:R:S63	R:R:Y14	3.82	Yes	Yes	1	5	4
17	R:R:M64	R:R:Y14	7.18	Yes	Yes	1	3	4
18	R:R:N67	R:R:Y14	5.81	Yes	Yes	1	3	4
19	R:R:E262	R:R:Y14	19.08	Yes	Yes	1	3	4
20	R:R:Y14	R:R:Y266	14.89	Yes	Yes	1	4	4
21	R:R:A267	R:R:E17	4.53	No	No	0	6	8
22	R:R:Q60	R:R:S18	4.33	Yes	No	1	7	6
23	R:R:M64	R:R:S18	6.13	Yes	No	1	3	6
24	R:R:I21	R:R:Q60	6.86	No	Yes	0	8	7
25	R:R:I21	R:R:L270	4.28	No	Yes	0	8	7
26	R:R:I22	R:R:Q60	5.49	No	Yes	0	7	7
27	R:R:I22	R:R:W61	8.22	No	No	0	7	3
28	R:R:L270	R:R:Q24	3.99	Yes	No	0	7	7
29	R:R:Q24	R:R:S273	5.78	No	No	0	7	9
30	R:R:Q24	R:R:T274	4.25	No	No	0	7	4
31	R:R:F57	R:R:S25	3.96	No	No	0	6	9
32	R:R:I28	R:R:L32	4.28	Yes	Yes	2	9	8
33	R:R:I28	R:R:L49	7.14	Yes	Yes	2	9	8
34	R:R:I28	R:R:M277	4.37	Yes	No	0	9	9
35	R:R:I28	R:R:S280	3.1	Yes	No	2	9	9
36	R:R:L32	R:R:L42	4.15	Yes	Yes	2	8	7
37	R:R:D46	R:R:L32	5.43	Yes	Yes	2	9	8
38	R:R:I50	R:R:L32	7.14	No	Yes	0	6	8
39	R:R:G33	R:R:W36	4.22	No	Yes	0	4	6
40	R:R:E35	R:R:Q38	7.65	No	No	0	7	6
41	R:R:E35	R:R:L42	6.63	No	Yes	2	7	7
42	R:R:E35	R:R:T282	4.23	No	No	2	7	8
43	R:R:R40	R:R:W36	13	No	Yes	0	7	6
44	R:R:L42	R:R:W36	6.83	Yes	Yes	0	7	6
45	R:R:I50	R:R:W36	5.87	No	Yes	0	6	6
46	R:R:Q38	R:R:V39	5.73	No	No	0	6	5
47	R:R:D46	R:R:L42	8.14	Yes	Yes	2	9	7
48	R:R:L42	R:R:T282	4.42	Yes	No	2	7	8
49	R:R:M43	R:R:P44	3.35	Yes	Yes	2	7	6
50	R:R:M43	R:R:V45	4.56	Yes	No	2	7	5
51	R:R:M43	R:R:P281	6.71	Yes	No	2	7	7
52	R:R:F102	R:R:P44	10.11	No	Yes	2	8	6
53	R:R:K106	R:R:P44	3.35	No	Yes	2	9	6
54	R:R:F126	R:R:P44	11.56	No	Yes	2	7	6
55	R:R:P281	R:R:V45	3.53	No	No	2	7	5
56	R:R:D46	R:R:L49	4.07	Yes	Yes	2	9	8
57	R:R:D46	R:R:P281	4.83	Yes	No	2	9	7
58	R:R:D46	R:R:T282	8.67	Yes	No	2	9	8
59	R:R:F126	R:R:M47	11.2	No	No	2	7	5
60	R:R:M47	R:R:P127	3.35	No	No	2	5	7
61	R:R:I48	R:R:L95	4.28	No	Yes	0	9	7
62	R:R:I48	R:R:L98	5.71	No	No	0	9	6
63	R:R:I48	R:R:L99	7.14	No	No	0	9	9
64	R:R:L276	R:R:L49	4.15	No	Yes	0	9	8
65	R:R:L49	R:R:S280	4.5	Yes	No	2	8	9
66	R:R:L95	R:R:S51	7.51	Yes	No	0	7	7
67	R:R:L130	R:R:S51	4.5	No	No	0	8	7
68	R:R:L52	R:R:L95	9.69	No	Yes	0	9	7
69	R:R:I54	R:R:S55	3.1	No	No	0	6	8
70	R:R:L91	R:R:S55	9.01	No	No	0	6	8
71	R:R:R56	R:R:T92	3.88	No	No	0	9	8
72	R:R:I269	R:R:R56	11.27	No	No	0	8	9
73	R:R:H272	R:R:R56	15.8	Yes	No	0	9	9
74	R:R:F57	R:R:W61	5.01	No	No	0	6	3
75	R:R:C58	R:R:F88	15.36	No	No	0	2	4
76	R:R:L59	R:R:W85	21.64	No	Yes	1	5	5
77	R:R:L59	R:R:Y266	5.86	No	Yes	1	5	4
78	R:R:M64	R:R:Q60	4.08	Yes	Yes	1	3	7
79	R:R:Q60	R:R:Y266	10.15	Yes	Yes	1	7	4
80	R:R:M64	R:R:W61	5.82	Yes	No	0	3	3
81	R:R:A62	R:R:W85	3.89	No	Yes	0	4	5
82	R:R:N67	R:R:S63	4.47	Yes	Yes	1	3	5
83	R:R:S63	R:R:W85	3.71	Yes	Yes	1	5	5
84	R:R:S63	R:R:Y266	11.45	Yes	Yes	1	5	4
85	L:L:?1	R:R:S63	3.95	Yes	Yes	1	0	5
86	R:R:L65	R:R:L81	5.54	No	No	0	4	2
87	L:L:?1	R:R:N66	5.42	Yes	No	0	0	5
88	R:R:N67	R:R:W259	3.39	Yes	Yes	1	3	3
89	R:R:E262	R:R:N67	11.83	Yes	Yes	1	3	3
90	R:R:F68	R:R:F72	11.79	No	Yes	1	3	3
91	R:R:F68	R:R:W259	13.03	No	Yes	1	3	3
92	R:R:C69	R:R:S70	3.44	No	No	0	3	3
93	R:R:C69	R:R:C79	7.28	No	No	0	3	3
94	R:R:F72	R:R:Y71	11.35	Yes	No	1	3	2
95	R:R:L258	R:R:Y71	3.52	No	No	1	2	2
96	R:R:W259	R:R:Y71	21.22	Yes	No	1	3	2
97	R:R:F72	R:R:W259	6.01	Yes	Yes	1	3	3
98	R:R:N73	R:R:Y76	6.98	No	No	0	3	2
99	R:R:C79	R:R:Y76	5.38	No	No	0	3	2
100	R:R:N80	R:R:T82	4.39	No	No	0	3	1
101	R:R:L81	R:R:T84	5.9	No	No	0	2	2
102	R:R:I83	R:R:N148	5.66	No	No	0	4	3
103	R:R:F88	R:R:T84	7.78	No	No	0	4	2
104	R:R:N89	R:R:W85	9.04	Yes	Yes	1	8	5
105	R:R:W85	R:R:Y239	3.86	Yes	Yes	1	5	7
106	R:R:I243	R:R:W85	3.52	Yes	Yes	1	3	5
107	R:R:W85	R:R:Y266	7.72	Yes	Yes	1	5	4
108	L:L:?1	R:R:W85	30.71	Yes	Yes	1	0	5
109	R:R:E86	R:R:I90	8.2	Yes	No	0	4	6
110	R:R:E86	R:R:I141	5.47	Yes	No	0	4	5
111	R:R:E86	R:R:H181	4.92	Yes	Yes	1	4	2
112	L:L:?1	R:R:E86	3.49	Yes	Yes	1	0	4
113	R:R:F87	R:R:T137	11.67	No	No	0	7	8
114	R:R:C138	R:R:F87	4.19	No	No	0	3	7
115	R:R:F93	R:R:N89	9.67	Yes	Yes	1	6	8
116	R:R:N89	R:R:Y239	11.63	Yes	Yes	1	8	7
117	R:R:I243	R:R:N89	7.08	Yes	Yes	1	3	8
118	R:R:I90	R:R:T137	6.08	No	No	0	6	8
119	R:R:A184	R:R:I90	3.25	No	No	0	4	6
120	R:R:L134	R:R:L91	4.15	No	No	0	5	6
121	R:R:L91	R:R:T137	8.84	No	No	0	6	8
122	R:R:F93	R:R:L185	4.87	Yes	No	0	6	5
123	R:R:F236	R:R:F93	17.15	Yes	Yes	1	7	6
124	R:R:F93	R:R:Y239	6.19	Yes	Yes	1	6	7
125	R:R:F240	R:R:F93	5.36	Yes	Yes	0	6	6
126	R:R:I136	R:R:W94	8.22	No	No	0	4	9
127	R:R:P188	R:R:W94	32.43	No	No	0	8	9
128	R:R:C133	R:R:L95	3.17	No	Yes	0	8	7
129	R:R:L99	R:R:N96	5.49	No	Yes	0	9	7
130	R:R:F192	R:R:N96	8.46	Yes	Yes	1	8	7
131	R:R:F236	R:R:N96	10.87	Yes	Yes	1	7	7
132	R:R:H272	R:R:N96	10.2	Yes	Yes	1	9	7
133	R:R:L191	R:R:S97	4.5	No	No	0	5	8
134	R:R:F192	R:R:S97	3.96	Yes	No	0	8	8
135	R:R:L99	R:R:Y103	10.55	No	No	0	9	9
136	R:R:F192	R:R:T100	9.08	Yes	No	1	8	8
137	R:R:S195	R:R:T100	4.8	No	No	0	8	8
138	R:R:T100	R:R:T196	6.28	No	Yes	1	8	7
139	R:R:L191	R:R:V101	4.47	No	No	0	5	7
140	R:R:S195	R:R:V101	6.46	No	No	0	8	7
141	R:R:F102	R:R:K106	11.17	No	No	2	8	9
142	R:R:C104	R:R:F198	9.78	No	No	0	8	7
143	R:R:I105	R:R:R119	5.01	No	No	0	7	9
144	R:R:F110	R:R:S108	6.61	Yes	No	0	8	7
145	R:R:F115	R:R:S108	7.93	Yes	No	0	9	7
146	R:R:Q206	R:R:S109	5.78	No	No	0	5	7
147	R:R:F110	R:R:F198	12.86	Yes	No	0	8	7
148	R:R:F110	R:R:S202	7.93	Yes	No	0	8	9
149	R:R:H112	R:R:H113	13.14	No	No	4	7	5
150	R:R:H112	R:R:I114	7.95	No	No	4	7	4
151	R:R:F115	R:R:H112	3.39	Yes	No	0	9	7
152	R:R:H113	R:R:I114	11.93	No	No	4	5	4
153	R:R:F115	R:R:F198	5.36	Yes	No	0	9	7
154	R:R:R121	R:R:W117	28.99	No	No	0	8	6
155	R:R:I122	R:R:L118	4.28	No	No	0	8	8
156	R:R:R124	R:R:W120	6	No	No	0	5	4
157	R:R:I122	R:R:I129	4.42	No	No	0	8	7
158	R:R:L125	R:R:R124	4.86	No	No	0	6	5
159	R:R:L125	R:R:W128	6.83	No	No	0	6	3
160	R:R:F126	R:R:P127	4.33	No	No	2	7	7
161	R:R:I136	R:R:V139	4.61	No	No	0	4	4
162	R:R:I136	R:R:T140	3.04	No	No	0	4	5
163	R:R:I141	R:R:S144	4.64	No	No	0	5	3
164	R:R:I142	R:R:P143	10.16	No	No	0	5	4
165	R:R:I146	R:R:P143	3.39	No	No	0	3	4
166	R:R:H181	R:R:S144	6.97	Yes	No	0	2	3
167	R:R:G147	R:R:Q177	4.93	No	Yes	0	3	1
168	R:R:Q153	R:R:Y149	15.78	No	No	0	3	3
169	R:R:F173	R:R:I150	8.79	No	Yes	0	4	2
170	R:R:H174	R:R:Q151	17.31	No	No	0	3	3
171	R:R:Q151	R:R:Q177	15.36	No	Yes	0	3	1
172	R:R:E171	R:R:Q175	14.02	No	No	0	3	1
173	R:R:E171	R:R:F178	9.33	No	No	0	3	4
174	R:R:F173	R:R:Y176	10.32	No	No	0	4	3
175	R:R:Q179	R:R:V183	5.73	No	No	0	4	5
176	R:R:H181	R:R:I247	3.98	Yes	No	1	2	4
177	L:L:?1	R:R:H181	3.38	Yes	Yes	1	0	2
178	R:R:T182	R:R:V186	3.17	No	No	0	4	3
179	R:R:I247	R:R:T182	3.04	No	No	0	4	4
180	R:R:I243	R:R:L185	4.28	Yes	No	0	3	5
181	R:R:I190	R:R:V186	3.07	No	No	0	4	3
182	R:R:I187	R:R:P188	3.39	No	No	0	5	8
183	R:R:F189	R:R:F192	4.29	No	Yes	0	6	8
184	R:R:F189	R:R:T237	7.78	No	No	0	6	5
185	R:R:F189	R:R:F240	21.43	No	Yes	0	6	6
186	R:R:F192	R:R:T196	7.78	Yes	Yes	1	8	7
187	R:R:F192	R:R:F236	3.22	Yes	Yes	1	8	7
188	R:R:F233	R:R:T196	7.78	Yes	Yes	0	7	7
189	R:R:L199	R:R:L229	4.15	No	No	0	9	7
190	R:R:L226	R:R:M200	5.65	No	Yes	0	7	8
191	R:R:L229	R:R:M200	5.65	No	Yes	0	7	8
192	R:R:I207	R:R:L203	4.28	Yes	No	0	8	9
193	R:R:L203	R:R:L226	15.22	No	No	0	9	7
194	R:R:I207	R:R:T204	3.04	Yes	No	0	8	6
195	R:R:L226	R:R:T204	4.42	No	No	0	7	6
196	R:R:H209	R:R:K205	11.79	No	No	0	5	5
197	R:R:Q206	R:R:R222	14.02	No	No	0	5	9
198	R:R:F223	R:R:I207	5.02	No	Yes	0	6	8
199	R:R:H210	R:R:R222	10.16	No	No	0	6	9
200	R:R:C215	R:R:S218	6.89	No	No	0	6	8
201	R:R:F223	R:R:M219	7.46	No	No	0	6	7
202	R:R:S228	R:R:V231	3.23	No	No	0	7	7
203	R:R:S275	R:R:V231	3.23	No	No	0	7	7
204	R:R:L232	R:R:S275	4.5	No	No	0	8	7
205	R:R:F233	R:R:T237	7.78	Yes	No	0	7	5
206	R:R:M271	R:R:V235	16.74	No	No	0	4	7
207	R:R:F236	R:R:Y239	4.13	Yes	Yes	1	7	7
208	R:R:F236	R:R:H272	10.18	Yes	Yes	1	7	9
209	R:R:F268	R:R:S238	11.89	No	No	0	5	6
210	R:R:T242	R:R:Y239	4.99	No	Yes	1	6	7
211	R:R:I243	R:R:Y239	13.3	Yes	Yes	1	3	7
212	R:R:V265	R:R:Y239	3.79	No	Yes	1	4	7
213	R:R:I269	R:R:Y239	10.88	No	Yes	0	8	7
214	R:R:F240	R:R:L241	7.31	Yes	No	0	6	4
215	R:R:F240	R:R:L244	18.27	Yes	No	0	6	4
216	R:R:I243	R:R:T242	4.56	Yes	No	1	3	6
217	R:R:T242	R:R:V265	7.93	No	No	1	6	4
218	R:R:I245	R:R:W261	4.7	No	Yes	0	5	4
219	L:L:?1	R:R:T246	6.79	Yes	No	0	0	4
220	L:L:?1	R:R:I247	3.76	Yes	No	1	0	4
221	R:R:G249	R:R:I248	3.53	No	No	0	5	4
222	R:R:L251	R:R:T250	5.9	No	No	0	1	3
223	R:R:F252	R:R:K254	3.72	No	Yes	1	2	3
224	R:R:F252	R:R:W257	25.05	No	Yes	0	2	3
225	R:R:F252	R:R:W261	37.08	No	Yes	1	2	4
226	R:R:D253	R:R:R255	3.57	No	No	0	1	5
227	R:R:C256	R:R:D253	12.45	No	No	0	1	1
228	R:R:K254	R:R:L258	4.23	Yes	No	1	3	2
229	R:R:K254	R:R:W261	9.28	Yes	Yes	1	3	4
230	R:R:E262	R:R:K254	5.4	Yes	Yes	1	3	3
231	L:L:?1	R:R:K254	7.42	Yes	Yes	1	0	3
232	R:R:V260	R:R:W257	14.71	No	Yes	0	4	3
233	R:R:L258	R:R:W259	18.22	No	Yes	1	2	3
234	R:R:F264	R:R:W261	9.02	No	Yes	0	4	4
235	R:R:E262	R:R:Y266	4.49	Yes	Yes	1	3	4
236	L:L:?1	R:R:E262	6.97	Yes	Yes	1	0	3
237	R:R:F264	R:R:F268	9.65	No	No	0	4	5
238	R:R:V265	R:R:Y266	5.05	No	Yes	1	4	4
239	R:R:I269	R:R:Y266	3.63	No	Yes	0	8	4
240	R:R:H272	R:R:L276	6.43	Yes	No	0	9	9
241	R:R:L283	R:R:S280	6.01	No	No	0	9	9
242	R:R:M200	R:R:T196	3.01	Yes	Yes	0	8	7
243	R:R:L19	R:R:V15	2.98	No	No	0	6	4
244	R:R:L283	R:R:V31	2.98	No	No	0	9	8
245	R:R:L270	R:R:T20	2.95	Yes	No	0	7	5
246	L:L:?1	R:R:T82	2.91	Yes	No	0	0	1
247	R:R:F93	R:R:P188	2.89	Yes	No	0	6	8
248	R:R:I12	R:R:L16	2.85	No	No	0	5	5
249	R:R:I129	R:R:L98	2.85	No	No	0	7	6
250	R:R:I150	R:R:L154	2.85	Yes	No	0	2	2
251	R:R:I197	R:R:L193	2.85	No	No	0	5	6
252	R:R:L27	R:R:M277	2.83	No	No	0	8	9
253	R:R:L278	R:R:M277	2.83	No	No	0	6	9
254	R:R:K106	R:R:L123	2.82	No	No	0	9	7
255	R:R:L131	R:R:L134	2.77	No	No	0	5	5
256	R:R:L229	R:R:L232	2.77	No	No	0	7	8
257	R:R:I150	R:R:Q151	2.74	Yes	No	0	2	3
258	R:R:I152	R:R:Q153	2.74	No	No	0	2	3
259	R:R:P127	R:R:W128	2.7	No	No	0	7	3
260	R:R:E17	R:R:L270	2.65	No	Yes	0	8	7
261	R:R:F110	R:R:S109	2.64	Yes	No	0	8	7
262	R:R:R227	R:R:S228	2.64	No	No	0	7	7
263	R:R:R41	R:R:V39	2.62	No	No	0	5	5
264	R:R:C256	R:R:W257	2.61	No	Yes	0	1	3
265	R:R:F115	R:R:I105	2.51	Yes	No	0	9	7
266	R:R:F233	R:R:I197	2.51	Yes	No	0	7	5
267	R:R:I207	R:R:R222	2.51	Yes	No	0	8	9
268	R:R:F233	R:R:I234	2.51	Yes	No	0	7	5
269	R:R:F268	R:R:M271	2.49	No	No	0	5	4
270	R:R:H181	R:R:Q177	2.47	Yes	Yes	0	2	1
271	R:R:L116	R:R:R119	2.43	No	No	0	6	9
272	R:R:F178	R:R:H174	2.26	No	No	0	4	3
273	R:R:G53	R:R:S25	1.86	No	No	0	8	9
274	R:R:G249	R:R:T250	1.82	No	No	0	5	3
275	R:R:G147	R:R:I146	1.76	No	No	0	3	3
276	R:R:G132	R:R:M135	1.75	No	No	0	5	5
277	R:R:G132	R:R:L131	1.71	No	No	0	5	5
278	R:R:A62	R:R:T84	1.68	No	No	0	4	2
279	R:R:N216	R:R:P217	1.63	No	No	0	8	5
280	R:R:A145	R:R:I83	1.62	No	No	0	4	4
281	R:R:A230	R:R:M200	1.61	No	Yes	0	5	8
282	R:R:V183	R:R:V186	1.6	No	No	0	5	3
283	R:R:G213	R:R:H214	1.59	No	No	0	7	5
284	R:R:A225	R:R:L203	1.58	No	No	0	9	9
285	R:R:I22	R:R:S26	1.55	No	No	0	7	8
286	R:R:I54	R:R:V29	1.54	No	No	0	6	6
287	R:R:M11	R:R:V8	1.52	Yes	No	0	4	4
288	R:R:M11	R:R:V15	1.52	Yes	No	0	4	4
289	R:R:A180	R:R:Q179	1.52	No	No	0	3	4
290	R:R:L155	R:R:T156	1.47	No	No	0	3	1
291	R:R:C215	R:R:H210	1.47	No	No	0	6	6
292	R:R:I245	R:R:L251	1.43	No	No	0	5	1
293	R:R:Q153	R:R:T156	1.42	No	No	0	3	1
294	R:R:M219	R:R:N216	1.4	No	No	0	7	8
295	R:R:A263	R:R:F10	1.39	No	No	0	5	5
296	R:R:I207	R:R:Q208	1.37	Yes	No	0	8	6
297	R:R:N148	R:R:Q177	1.32	No	Yes	0	3	1
298	R:R:S279	R:R:Y103	1.27	No	No	0	7	9
299	R:R:M43	R:R:R285	1.24	Yes	No	0	7	6
300	R:R:I150	R:R:Y149	1.21	Yes	No	0	2	3
301	R:R:H209	R:R:H210	1.19	No	No	0	5	6
302	R:R:L118	R:R:W117	1.14	No	No	0	8	6

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:I2	5.0275	4	3	6
2	R:R:M11	8.262	5	1	4
3	R:R:Y14	8.62571	7	1	4
4	R:R:I28	4.7225	4	2	9
5	R:R:L32	5.25	4	2	8
6	R:R:W36	7.48	4	0	6
7	R:R:L42	6.034	5	2	7
8	R:R:M43	3.965	4	2	7
9	R:R:P44	7.0925	4	2	6
10	R:R:D46	6.228	5	2	9
11	R:R:L49	4.965	4	2	8
12	R:R:Q60	5.90333	6	1	7
13	R:R:S63	5.48	5	1	5
14	R:R:M64	5.8025	4	1	3
15	R:R:N67	6.375	4	1	3
16	R:R:F72	9.775	4	1	3
17	R:R:W85	10.5112	8	1	5
18	R:R:E86	5.52	4	1	4
19	R:R:N89	9.355	4	1	8
20	R:R:F93	7.68833	6	1	6
21	R:R:L95	6.1625	4	0	7
22	R:R:N96	8.755	4	1	7
23	R:R:F110	7.51	4	0	8
24	R:R:F115	4.7975	4	0	9
25	R:R:I150	3.8975	4	0	2
26	R:R:Q177	6.02	4	0	1
27	R:R:H181	4.344	5	1	2
28	R:R:F192	6.13167	6	1	8
29	R:R:T196	6.2125	4	1	7
30	R:R:M200	3.98	4	0	8
31	R:R:I207	3.244	5	0	8
32	R:R:F233	5.145	4	0	7
33	R:R:F236	9.11	5	1	7
34	R:R:Y239	7.34625	8	1	7
35	R:R:F240	13.0925	4	0	6
36	R:R:I243	6.548	5	1	3
37	R:R:K254	6.01	5	1	3
38	R:R:W257	12.9425	4	0	3
39	R:R:W259	13.995	6	1	3
40	R:R:W261	15.02	4	1	4
41	R:R:E262	9.554	5	1	3
42	R:R:Y266	7.905	8	1	4
43	R:R:L270	3.4675	4	0	7
44	R:R:H272	10.6525	4	1	9
45	L:L:?1	7.48	10	1	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:E17	R:R:L270	11.6235	2.65	No	Yes	0	8	7
2	R:R:I21	R:R:L270	25.9935	4.28	No	Yes	0	8	7
3	R:R:I21	R:R:Q60	28.8457	6.86	No	Yes	0	8	7
4	R:R:F252	R:R:K254	15.9145	3.72	No	Yes	1	2	3
5	R:R:F252	R:R:W257	15.2005	25.05	No	Yes	0	2	3
6	R:R:Q60	R:R:Y266	46.749	10.15	Yes	Yes	1	7	4
7	R:R:E262	R:R:Y266	12.6325	4.49	Yes	Yes	1	3	4
8	R:R:I22	R:R:Q60	12.5851	5.49	No	Yes	0	7	7
9	R:R:M64	R:R:Y14	13.3574	7.18	Yes	Yes	1	3	4
10	R:R:M64	R:R:W61	17.6775	5.82	Yes	No	0	3	3
11	R:R:F57	R:R:W61	18.3987	5.01	No	No	0	6	3
12	R:R:F57	R:R:S25	12.2719	3.96	No	No	0	6	9
13	R:R:I269	R:R:Y266	32.4591	3.63	No	Yes	0	8	4
14	R:R:I269	R:R:R56	18.06	11.27	No	No	0	8	9
15	R:R:H272	R:R:R56	17.5646	15.8	Yes	No	0	9	9
16	R:R:H272	R:R:L276	61.8767	6.43	Yes	No	0	9	9
17	R:R:L276	R:R:L49	60.5398	4.15	No	Yes	0	9	8
18	L:L:?1	R:R:K254	25.0792	7.42	Yes	Yes	1	0	3
19	L:L:?1	R:R:W85	58.1357	30.71	Yes	Yes	1	0	5
20	R:R:W85	R:R:Y239	76.407	3.86	Yes	Yes	1	5	7
21	R:R:F236	R:R:Y239	97.5267	4.13	Yes	Yes	1	7	7
22	R:R:F236	R:R:H272	32.8817	10.18	Yes	Yes	1	7	9
23	R:R:D46	R:R:L49	46.3192	4.07	Yes	Yes	2	9	8
24	R:R:D46	R:R:L42	12.4977	8.14	Yes	Yes	2	9	7
25	R:R:D46	R:R:P281	23.4401	4.83	Yes	No	2	9	7
26	R:R:M43	R:R:P281	20.3038	6.71	Yes	No	2	7	7
27	R:R:M43	R:R:P44	17.2185	3.35	Yes	Yes	2	7	6
28	R:R:F126	R:R:P44	11.2046	11.56	No	Yes	2	7	6
29	R:R:F236	R:R:N96	12.5924	10.87	Yes	Yes	1	7	7
30	R:R:L99	R:R:N96	21.2545	5.49	No	Yes	0	9	7
31	R:R:I48	R:R:L99	17.091	7.14	No	No	0	9	9
32	L:L:?1	R:R:E86	19.2766	3.49	Yes	Yes	1	0	4
33	R:R:E86	R:R:I90	18.3696	8.2	Yes	No	0	4	6
34	R:R:I90	R:R:T137	15.6231	6.08	No	No	0	6	8
35	R:R:L91	R:R:T137	11.4487	8.84	No	No	0	6	8
36	R:R:F93	R:R:P188	11.1427	2.89	Yes	No	0	6	8
37	R:R:F192	R:R:F236	87.8556	3.22	Yes	Yes	1	8	7
38	R:R:F192	R:R:T196	100	7.78	Yes	Yes	1	8	7
39	R:R:F110	R:R:F198	23.4218	12.86	Yes	No	0	8	7
40	R:R:F110	R:R:S109	49.3243	2.64	Yes	No	0	8	7
41	R:R:Q206	R:R:S109	51.6046	5.78	No	No	0	5	7
42	R:R:Q206	R:R:R222	54.1216	14.02	No	No	0	5	9
43	R:R:I207	R:R:R222	68.8158	2.51	Yes	No	0	8	9
44	R:R:I207	R:R:L203	41.8133	4.28	Yes	No	0	8	9
45	R:R:L203	R:R:L226	44.1045	15.22	No	No	0	9	7
46	R:R:L226	R:R:M200	87.8556	5.65	No	Yes	0	7	8
47	R:R:M200	R:R:T196	96.6561	3.01	Yes	Yes	0	8	7
48	R:R:I207	R:R:T204	41.7004	3.04	Yes	No	0	8	6
49	R:R:L226	R:R:T204	42.8405	4.42	No	No	0	7	6
50	R:R:F115	R:R:I105	15.6886	2.51	Yes	No	0	9	7
51	R:R:F115	R:R:S108	18.253	7.93	Yes	No	0	9	7
52	R:R:F110	R:R:S108	20.8393	6.61	Yes	No	0	8	7
53	R:R:F115	R:R:F198	18.2749	5.36	Yes	No	0	9	7
54	R:R:I105	R:R:R119	10.4688	5.01	No	No	0	7	9
55	R:R:F115	R:R:H112	15.6996	3.39	Yes	No	0	9	7
56	R:R:H181	R:R:Q177	29.3702	2.47	Yes	Yes	0	2	1
57	L:L:?1	R:R:H181	29.6907	3.38	Yes	Yes	1	0	2
58	R:R:Q151	R:R:Q177	19.2365	15.36	No	Yes	0	3	1
59	R:R:I150	R:R:Q151	12.6106	2.74	Yes	No	0	2	3
60	R:R:L229	R:R:M200	10.4397	5.65	No	Yes	0	7	8
61	R:R:H210	R:R:R222	13.2299	10.16	No	No	0	6	9
62	R:R:F223	R:R:I207	10.589	5.02	No	Yes	0	6	8
63	R:R:V265	R:R:Y266	15.5174	5.05	No	Yes	1	4	4
64	R:R:N67	R:R:W259	13.2845	3.39	Yes	Yes	1	3	3
65	R:R:W85	R:R:Y266	20.2054	7.72	Yes	Yes	1	5	4
66	R:R:V265	R:R:Y239	15.124	3.79	No	Yes	1	4	7
67	R:R:I269	R:R:Y239	15.4846	10.88	No	Yes	0	8	7
68	R:R:H272	R:R:N96	19.6736	10.2	Yes	Yes	1	9	7
69	R:R:K254	R:R:W261	13.4849	9.28	Yes	Yes	1	3	4
70	R:R:Y14	R:R:Y266	13.1534	14.89	Yes	Yes	1	4	4
71	R:R:S63	R:R:W85	10.6181	3.71	Yes	Yes	1	5	5
72	R:R:F192	R:R:N96	20.7154	8.46	Yes	Yes	1	8	7

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:S63	R:R:Y14	3.82	1	Yes	Yes	5	4	1	2
R:R:N67	R:R:Y14	5.81	1	Yes	Yes	3	4	2	2
R:R:E262	R:R:Y14	19.08	1	Yes	Yes	3	4	1	2
R:R:Y14	R:R:Y266	14.89	1	Yes	Yes	4	4	2	2
R:R:L59	R:R:W85	21.64	1	No	Yes	5	5	2	1
R:R:L59	R:R:Y266	5.86	1	No	Yes	5	4	2	2
R:R:A62	R:R:W85	3.89	0	No	Yes	4	5	2	1
R:R:N67	R:R:S63	4.47	1	Yes	Yes	3	5	2	1
R:R:S63	R:R:W85	3.71	1	Yes	Yes	5	5	1	1
R:R:S63	R:R:Y266	11.45	1	Yes	Yes	5	4	1	2
L:L:?1	R:R:S63	3.95	1	Yes	Yes	0	5	0	1
L:L:?1	R:R:N66	5.42	1	Yes	No	0	5	0	1
R:R:E262	R:R:N67	11.83	1	Yes	Yes	3	3	1	2
R:R:N80	R:R:T82	4.39	0	No	No	3	1	2	1
R:R:N89	R:R:W85	9.04	1	Yes	Yes	8	5	2	1
R:R:W85	R:R:Y239	3.86	1	Yes	Yes	5	7	1	2
R:R:I243	R:R:W85	3.52	1	Yes	Yes	3	5	2	1
R:R:W85	R:R:Y266	7.72	1	Yes	Yes	5	4	1	2
L:L:?1	R:R:W85	30.71	1	Yes	Yes	0	5	0	1
R:R:E86	R:R:I90	8.2	1	Yes	No	4	6	1	2
R:R:E86	R:R:I141	5.47	1	Yes	No	4	5	1	2
R:R:E86	R:R:H181	4.92	1	Yes	Yes	4	2	1	1
L:L:?1	R:R:E86	3.49	1	Yes	Yes	0	4	0	1
R:R:N89	R:R:Y239	11.63	1	Yes	Yes	8	7	2	2
R:R:I243	R:R:N89	7.08	1	Yes	Yes	3	8	2	2
R:R:I141	R:R:S144	4.64	0	No	No	5	3	2	2
R:R:H181	R:R:S144	6.97	1	Yes	No	2	3	1	2
R:R:H181	R:R:I247	3.98	1	Yes	No	2	4	1	1
L:L:?1	R:R:H181	3.38	1	Yes	Yes	0	2	0	1
R:R:I247	R:R:T182	3.04	1	No	No	4	4	1	2
R:R:I243	R:R:Y239	13.3	1	Yes	Yes	3	7	2	2
L:L:?1	R:R:T246	6.79	1	Yes	No	0	4	0	1
L:L:?1	R:R:I247	3.76	1	Yes	No	0	4	0	1
R:R:F252	R:R:K254	3.72	1	No	Yes	2	3	2	1
R:R:F252	R:R:W261	37.08	1	No	Yes	2	4	2	2
R:R:K254	R:R:L258	4.23	1	Yes	No	3	2	1	2
R:R:K254	R:R:W261	9.28	1	Yes	Yes	3	4	1	2
R:R:E262	R:R:K254	5.4	1	Yes	Yes	3	3	1	1
L:L:?1	R:R:K254	7.42	1	Yes	Yes	0	3	0	1
R:R:E262	R:R:Y266	4.49	1	Yes	Yes	3	4	1	2
L:L:?1	R:R:E262	6.97	1	Yes	Yes	0	3	0	1
L:L:?1	R:R:T82	2.91	1	Yes	No	0	1	0	1
R:R:H181	R:R:Q177	2.47	1	Yes	Yes	2	1	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	9KPD_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.04
Number of Linked Nodes	251
Number of Links	302
Number of Hubs	45
Number of Links mediated by Hubs	163
Number of Communities	4
Number of Nodes involved in Communities	58
Number of Links involved in Communities	97

Path Summary
Number Of Nodes in MetaPath	73
Number Of Links MetaPath	72
Number of Shortest Paths	64487
Length Of Smallest Path	3
Average Path Length	13.2515
Length of Longest Path	29
Minimum Path Strength	1.33
Average Path Strength	6.86789
Maximum Path Strength	31.065
Minimum Path Correlation	0.7
Average Path Correlation	0.93082
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	4.7619
Average % Of Corr. Nodes	46.1071
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	54.5561
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	SA0
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	SA0
Name	Salicin
Synonyms	D-salicin
Identifier
Formula	C13 H18 O7
Molecular Weight	286.278
SMILES
PubChem	439503
Formal Charge	0
Total Atoms	38
Total Chiral Atoms	5
Total Bonds	39
Total Aromatic Bonds	6


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q9NYV7
Sequence	>9KPD_nogp_Chain_R I P I Q L T V F F M I I Y V L E S L T I I V Q S S L I V A V L G R E W L Q V R R L M P V D M I L I S L G I S R F C L Q W A S M L N N F C S Y F N L N Y V L C N L T I T W E F F N I L T F W L N S L L T V F Y C I K V S S F T H H I F L W L R W R I L R L F P W I L L G L M I T C V T I I P S A I G N Y I Q I Q L L T E N F H Q Y Q F Q A H T V A L V I P F I L F L A S T I F L M A S L T K Q I Q H H S T G H C N P S M K A R F T A L R S L A V L F I V F T S Y F L T I L I T I I G T L F D K R C W L W V W E A F V Y A F I L M H S T S L M L S S P T L K R C Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	9K6L	T2	Sensory	Taste2	TAS2R16	Homo sapiens	SA0	-	Gi2/β1/γ2	2.77	2025-04-02	To be published
	9K6L (No Gprot)	T2	Sensory	Taste2	TAS2R16	Homo sapiens	SA0	-		2.77	2025-04-02	To be published
	9KPD	T2	Sensory	Taste2	TAS2R16	Homo sapiens	SA0	-	chim(Gs-CtGt3)/β1/γ2	2.84	2025-04-02	To be published
	9KPD (No Gprot)	T2	Sensory	Taste2	TAS2R16	Homo sapiens	SA0	-		2.84	2025-04-02	To be published
	9KPE	T2	Sensory	Taste2	TAS2R16	Homo sapiens	SA0	-	Gi1/β1/γ2	3.35	2025-04-02	To be published
	9KPE (No Gprot)	T2	Sensory	Taste2	TAS2R16	Homo sapiens	SA0	-		3.35	2025-04-02	To be published
	9KPF	T2	Sensory	Taste2	TAS2R16	Homo sapiens	SA0	-	Gi1/β1/γ2	3.15	2025-04-02	To be published
	9KPF (No Gprot)	T2	Sensory	Taste2	TAS2R16	Homo sapiens	SA0	-		3.15	2025-04-02	To be published

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 9KPD_nogp.zip

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