psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:D121	8.36	Yes	No	0	0	8
2	L:L:?1	R:R:V122	11.8	Yes	No	2	0	7
3	L:L:?1	R:R:C125	5.59	Yes	No	0	0	6
4	L:L:?1	R:R:T126	5.19	Yes	No	0	0	7
5	L:L:?1	R:R:V194	5.24	Yes	No	2	0	4
6	L:L:?1	R:R:S204	10.57	Yes	No	0	0	6
7	L:L:?1	R:R:F302	9.64	Yes	Yes	2	0	6
8	L:L:?1	R:R:E305	16.32	Yes	No	2	0	7
9	R:R:I43	R:R:V38	9.22	Yes	No	0	4	2
10	R:R:I43	R:R:L44	5.71	Yes	No	0	4	5
11	R:R:I43	R:R:L46	11.42	Yes	No	4	4	5
12	R:R:I43	R:R:L47	5.71	Yes	Yes	4	4	6
13	R:R:L46	R:R:L47	6.92	No	Yes	4	5	6
14	R:R:L47	R:R:W325	4.56	Yes	Yes	0	6	6
15	R:R:G48	R:R:V51	3.68	No	No	0	3	6
16	R:R:L50	R:R:T54	4.42	No	No	0	7	7
17	R:R:A90	R:R:T54	3.36	No	No	0	7	7
18	R:R:F332	R:R:T54	3.89	No	No	0	6	7
19	R:R:F55	R:R:L59	10.96	No	No	0	6	4
20	R:R:L336	R:R:W57	5.69	No	No	0	6	8
21	R:R:D86	R:R:N58	8.08	Yes	No	5	9	9
22	R:R:N58	R:R:V87	4.43	No	No	0	9	7
23	R:R:N58	R:R:P335	4.89	No	No	5	9	9
24	R:R:F349	R:R:L60	9.74	No	No	0	8	6
25	R:R:F352	R:R:L60	3.65	No	No	0	6	6
26	R:R:T339	R:R:V61	3.17	No	Yes	0	7	9
27	R:R:A83	R:R:L62	3.15	No	No	0	9	7
28	R:R:F349	R:R:T64	6.49	No	No	0	8	7
29	R:R:I65	R:R:Y345	4.84	No	Yes	0	7	8
30	R:R:F352	R:R:R67	6.41	No	No	0	6	5
31	R:R:T70	R:R:V68	3.17	No	No	1	6	5
32	R:R:F71	R:R:V68	18.35	Yes	No	1	8	5
33	R:R:H72	R:R:R69	9.03	No	No	0	8	7
34	R:R:F71	R:R:T70	5.19	Yes	No	1	8	6
35	R:R:F71	R:R:H76	5.66	Yes	Yes	1	8	9
36	R:R:F71	R:R:Y345	11.35	Yes	Yes	1	8	8
37	R:R:H76	R:R:R73	4.51	Yes	No	0	9	7
38	R:R:P75	R:R:V74	3.53	No	Yes	1	8	5
39	R:R:R154	R:R:V74	7.85	Yes	Yes	1	8	5
40	R:R:K155	R:R:V74	10.62	No	Yes	0	3	5
41	R:R:S158	R:R:V74	3.23	No	Yes	1	7	5
42	R:R:H76	R:R:P75	4.58	Yes	No	1	9	8
43	R:R:P75	R:R:R154	12.97	No	Yes	1	8	8
44	R:R:H76	R:R:Y345	8.71	Yes	Yes	1	9	8
45	R:R:L78	R:R:N77	6.87	No	Yes	0	8	4
46	R:R:N77	R:R:S158	7.45	Yes	No	1	4	7
47	R:R:N159	R:R:N77	4.09	No	Yes	0	3	4
48	R:R:I162	R:R:N77	5.66	No	Yes	1	8	4
49	R:R:V79	R:R:Y345	5.05	No	Yes	0	8	8
50	R:R:N131	R:R:S81	8.94	No	No	0	7	9
51	R:R:I162	R:R:S81	3.1	No	No	0	8	9
52	R:R:S81	R:R:W166	6.18	No	No	0	9	9
53	R:R:M82	R:R:N334	8.41	No	No	0	9	9
54	R:R:A127	R:R:S85	3.42	No	No	6	8	8
55	R:R:S128	R:R:S85	3.26	No	No	0	9	8
56	R:R:S85	R:R:W166	4.94	No	No	6	8	9
57	R:R:D86	R:R:S331	8.83	Yes	No	0	9	9
58	R:R:D86	R:R:N334	6.73	Yes	No	0	9	9
59	R:R:D86	R:R:P335	3.22	Yes	No	5	9	9
60	R:R:V89	R:R:V93	8.02	No	No	0	7	7
61	R:R:C120	R:R:L92	3.17	No	No	0	5	5
62	R:R:C120	R:R:V93	3.42	No	No	0	5	7
63	R:R:D121	R:R:V93	4.38	No	No	0	8	7
64	R:R:M94	R:R:P95	3.35	No	No	0	7	9
65	R:R:M94	R:R:Y328	4.79	No	No	0	7	7
66	R:R:L96	R:R:W117	7.97	No	Yes	0	5	5
67	R:R:S97	R:R:W117	4.94	No	Yes	0	6	5
68	R:R:S97	R:R:Y328	3.82	No	No	0	6	7
69	R:R:Q108	R:R:V99	5.73	No	No	0	3	5
70	R:R:H100	R:R:R105	5.64	No	No	0	5	6
71	R:R:H100	R:R:W107	8.46	No	Yes	3	5	8
72	R:R:H100	R:R:W117	12.7	No	Yes	3	5	5
73	R:R:E101	R:R:R105	3.49	No	No	0	5	6
74	R:R:E101	R:R:W325	6.54	No	Yes	0	5	6
75	R:R:R105	R:R:S321	3.95	No	No	0	6	5
76	R:R:L113	R:R:W107	6.83	No	Yes	0	5	8
77	R:R:W107	R:R:W117	13.12	Yes	Yes	3	8	5
78	R:R:E190	R:R:W107	5.45	Yes	Yes	0	4	8
79	R:R:C192	R:R:W107	3.92	No	Yes	3	9	8
80	R:R:L109	R:R:R112	12.15	No	No	0	6	1
81	R:R:L109	R:R:L113	5.54	No	No	0	6	5
82	R:R:Q115	R:R:R111	9.35	No	Yes	7	6	4
83	R:R:R111	R:R:Y185	5.14	Yes	No	7	4	4
84	R:R:R111	R:R:S186	6.59	Yes	No	0	4	2
85	R:R:E190	R:R:R111	5.82	Yes	Yes	0	4	4
86	R:R:C114	R:R:C192	7.28	No	No	0	9	9
87	R:R:Q115	R:R:Y185	10.15	No	No	7	6	4
88	R:R:C192	R:R:W117	5.22	No	Yes	3	9	5
89	R:R:I118	R:R:V194	4.61	No	No	0	6	4
90	R:R:C120	R:R:C124	7.28	No	No	0	5	6
91	R:R:D121	R:R:Y328	10.34	No	No	0	8	7
92	R:R:V122	R:R:V194	3.21	No	No	2	7	4
93	R:R:C124	R:R:L123	3.17	No	No	0	6	5
94	R:R:L123	R:R:S173	9.01	No	No	0	5	8
95	R:R:A208	R:R:T126	3.36	No	No	0	7	7
96	R:R:A127	R:R:W166	7.78	No	No	6	8	9
97	R:R:A127	R:R:S169	3.42	No	No	0	8	8
98	R:R:I129	R:R:P212	3.39	No	Yes	0	8	9
99	R:R:I129	R:R:W298	5.87	No	Yes	0	8	8
100	R:R:T165	R:R:W130	3.64	No	No	0	6	6
101	R:R:L168	R:R:W130	6.83	No	No	0	4	6
102	R:R:P212	R:R:W130	13.51	Yes	No	0	9	6
103	R:R:N131	R:R:T165	4.39	No	No	0	7	6
104	R:R:F294	R:R:V132	3.93	No	No	0	9	8
105	R:R:V132	R:R:Y338	5.05	No	Yes	0	8	9
106	R:R:P212	R:R:T133	5.25	Yes	No	0	9	6
107	R:R:T133	R:R:V215	3.17	No	No	0	6	6
108	R:R:T133	R:R:V216	4.76	No	No	0	6	8
109	R:R:I135	R:R:R139	3.76	No	No	8	9	9
110	R:R:I135	R:R:Y338	6.04	No	Yes	8	9	9
111	R:R:A136	R:R:Y220	4	No	Yes	0	8	9
112	R:R:L137	R:R:W141	7.97	No	Yes	0	6	4
113	R:R:D138	R:R:Y149	8.05	No	Yes	1	9	8
114	R:R:D138	R:R:R154	13.1	No	Yes	1	9	8
115	R:R:R139	R:R:Y220	5.14	No	Yes	0	9	9
116	R:R:R139	R:R:Y338	6.17	No	Yes	8	9	9
117	R:R:W141	R:R:Y140	4.82	Yes	Yes	0	4	8
118	R:R:T144	R:R:Y140	8.74	No	Yes	0	6	8
119	R:R:V219	R:R:Y140	5.05	No	Yes	0	6	8
120	R:R:K222	R:R:Y140	7.17	No	Yes	0	5	8
121	R:R:I223	R:R:Y140	3.63	No	Yes	0	9	8
122	R:R:R145	R:R:W141	5	No	Yes	0	5	4
123	R:R:W141	R:R:Y149	8.68	Yes	Yes	0	4	8
124	R:R:E148	R:R:R145	15.12	No	No	0	5	5
125	R:R:R154	R:R:Y149	7.2	Yes	Yes	1	8	8
126	R:R:T150	R:R:T153	3.14	No	No	0	5	7
127	R:R:L151	R:R:R152	3.64	No	No	0	4	5
128	R:R:K155	R:R:N159	5.6	No	No	0	3	3
129	R:R:I162	R:R:S158	3.1	No	No	1	8	7
130	R:R:I172	R:R:L168	4.28	No	No	0	6	4
131	R:R:P176	R:R:Y200	11.13	No	Yes	0	7	7
132	R:R:L177	R:R:T184	5.9	No	No	0	6	4
133	R:R:F179	R:R:W181	10.02	No	Yes	0	4	7
134	R:R:E197	R:R:W181	10.9	No	Yes	0	6	7
135	R:R:S199	R:R:W181	4.94	No	Yes	0	3	7
136	R:R:W181	R:R:Y200	10.61	Yes	Yes	0	7	7
137	R:R:G182	R:R:S195	3.71	No	No	0	5	3
138	R:R:E191	R:R:S189	5.75	No	No	0	3	3
139	R:R:S195	R:R:Y200	8.9	No	Yes	0	3	7
140	R:R:E197	R:R:P198	9.43	No	No	0	6	4
141	R:R:S204	R:R:Y200	12.72	No	Yes	0	6	7
142	R:R:F302	R:R:T205	3.89	Yes	No	0	6	6
143	R:R:L306	R:R:T205	5.9	No	No	0	5	6
144	R:R:G207	R:R:V206	3.68	No	No	0	5	4
145	R:R:F209	R:R:Y210	4.13	Yes	No	0	8	5
146	R:R:F209	R:R:W298	4.01	Yes	Yes	2	8	8
147	R:R:F209	R:R:I299	6.28	Yes	No	0	8	6
148	R:R:F209	R:R:F302	17.15	Yes	Yes	2	8	6
149	R:R:L306	R:R:Y210	3.52	No	No	0	5	5
150	R:R:L211	R:R:P212	3.28	No	Yes	0	6	9
151	R:R:I291	R:R:L217	4.28	Yes	No	0	8	4
152	R:R:F218	R:R:K222	3.72	No	No	0	4	5
153	R:R:L290	R:R:Y220	3.52	No	Yes	0	8	9
154	R:R:I291	R:R:Y220	4.84	Yes	Yes	0	8	9
155	R:R:K225	R:R:W221	6.96	No	No	0	4	1
156	R:R:K222	R:R:K225	5.75	No	No	0	5	4
157	R:R:K228	R:R:Y224	8.36	No	No	0	5	6
158	R:R:A284	R:R:Y224	4	No	No	0	7	6
159	R:R:E280	R:R:K228	12.15	No	No	0	7	5
160	R:R:F229	R:R:R230	3.21	No	No	0	5	7
161	R:R:G232	R:R:V231	3.68	No	No	0	3	5
162	R:R:E277	R:R:R276	5.82	No	No	0	4	5
163	R:R:K279	R:R:Q278	8.14	No	No	0	5	5
164	R:R:Q278	R:R:R282	7.01	No	No	0	5	8
165	R:R:I289	R:R:L285	4.28	No	No	0	7	6
166	R:R:F341	R:R:M286	4.98	No	No	0	6	8
167	R:R:I337	R:R:L290	5.71	No	No	0	8	8
168	R:R:L290	R:R:Y338	4.69	No	Yes	0	8	9
169	R:R:I337	R:R:V293	4.61	No	No	0	8	5
170	R:R:C297	R:R:N330	11.02	No	No	0	8	9
171	R:R:F302	R:R:W298	8.02	Yes	Yes	2	6	8
172	R:R:G327	R:R:W298	7.04	No	Yes	0	7	8
173	R:R:N330	R:R:W298	9.04	No	Yes	0	9	8
174	R:R:I299	R:R:P300	3.39	No	No	0	6	9
175	R:R:F323	R:R:P300	4.33	No	No	0	5	9
176	R:R:E305	R:R:F301	16.32	No	No	0	7	7
177	R:R:F301	R:R:F323	3.22	No	No	0	7	5
178	R:R:F301	R:R:L324	6.09	No	No	0	7	5
179	R:R:E305	R:R:F302	3.5	No	Yes	2	7	6
180	R:R:S308	R:R:T304	3.2	No	Yes	0	3	5
181	R:R:P309	R:R:S308	3.56	No	No	0	5	3
182	R:R:C311	R:R:C313	5.46	No	No	0	3	1
183	R:R:I315	R:R:P316	3.39	No	No	0	4	5
184	R:R:I315	R:R:K320	5.82	No	No	0	4	4
185	R:R:P316	R:R:W319	4.05	No	No	0	5	4
186	R:R:S321	R:R:W325	3.71	No	Yes	0	5	6
187	R:R:I322	R:R:W325	3.52	No	Yes	0	3	6
188	R:R:F332	R:R:F333	7.5	No	No	0	6	6
189	R:R:T339	R:R:Y345	3.75	No	Yes	0	7	8
190	R:R:K343	R:R:N342	5.6	No	No	0	5	8
191	R:R:N342	R:R:Y345	9.3	No	Yes	0	8	8
192	R:R:K350	R:R:N346	5.6	No	No	0	7	9
193	R:R:I299	R:R:V295	3.07	No	No	0	6	5
194	R:R:M94	R:R:V51	3.04	No	No	0	7	6
195	R:R:I307	R:R:T304	3.04	No	Yes	0	5	5
196	R:R:I315	R:R:T304	3.04	No	Yes	0	4	5
197	R:R:F203	R:R:W181	3.01	No	Yes	0	4	7
198	R:R:L50	R:R:S329	3	No	No	0	7	4
199	R:R:L174	R:R:S173	3	No	No	0	4	8
200	R:R:L306	R:R:V202	2.98	No	No	0	5	6
201	R:R:N334	R:R:V132	2.96	No	No	0	9	8
202	R:R:P309	R:R:R196	2.88	No	No	0	5	4
203	R:R:E191	R:R:S186	2.87	No	No	0	3	2
204	R:R:M82	R:R:N131	2.8	No	No	0	9	7
205	R:R:C297	R:R:F333	2.79	No	No	0	8	6
206	R:R:A91	R:R:F55	2.77	No	No	0	4	6
207	R:R:A348	R:R:F71	2.77	No	Yes	0	7	8
208	R:R:L113	R:R:L116	2.77	No	No	0	5	4
209	R:R:L174	R:R:L178	2.77	No	No	0	4	5
210	R:R:L213	R:R:L217	2.77	No	No	0	5	4
211	R:R:N342	R:R:N344	2.72	No	No	0	8	7
212	R:R:E148	R:R:M147	2.71	No	No	0	5	7
213	R:R:L177	R:R:Q115	2.66	No	No	0	6	6
214	R:R:H146	R:R:M147	2.63	No	No	0	8	7
215	R:R:F55	R:R:V87	2.62	No	No	0	6	7
216	R:R:F349	R:R:V61	2.62	No	Yes	0	8	9
217	R:R:F323	R:R:T304	2.59	No	Yes	0	5	5
218	R:R:S142	R:R:Y149	2.54	No	Yes	0	8	8
219	R:R:V157	R:R:Y149	2.52	No	Yes	0	6	8
220	R:R:T153	R:R:Y149	2.5	No	Yes	0	7	8
221	R:R:V61	R:R:W57	2.45	Yes	No	0	9	8
222	R:R:Q193	R:R:R196	2.34	No	No	0	4	4
223	R:R:E190	R:R:R106	2.33	Yes	No	0	4	3
224	R:R:E183	R:R:Y185	2.24	No	No	0	4	4
225	R:R:Q108	R:R:W107	2.19	No	Yes	0	3	8
226	R:R:W221	R:R:Y224	1.93	No	No	0	1	6
227	R:R:A175	R:R:P176	1.87	No	No	0	7	7
228	R:R:A201	R:R:P309	1.87	No	No	0	6	5
229	R:R:G288	R:R:V287	1.84	No	No	0	6	8
230	R:R:G292	R:R:I291	1.76	No	Yes	0	5	8
231	R:R:G110	R:R:L109	1.71	No	No	0	7	6
232	R:R:C156	R:R:V157	1.71	No	No	0	5	6
233	R:R:C156	R:R:V160	1.71	No	No	0	5	3
234	R:R:A170	R:R:S173	1.71	No	No	0	4	8
235	R:R:G327	R:R:L326	1.71	No	No	0	7	8
236	R:R:A83	R:R:V61	1.7	No	Yes	0	9	9
237	R:R:E187	R:R:G188	1.64	No	No	0	2	4
238	R:R:E190	R:R:G188	1.64	Yes	No	0	4	4
239	R:R:A226	R:R:I143	1.62	No	No	0	6	9
240	R:R:A134	R:R:M161	1.61	No	No	0	7	5
241	R:R:V202	R:R:V206	1.6	No	No	0	6	4
242	R:R:C124	R:R:L88	1.59	No	No	0	6	6
243	R:R:A134	R:R:L78	1.58	No	No	0	7	8
244	R:R:I143	R:R:S142	1.55	No	No	0	9	8
245	R:R:I291	R:R:V287	1.54	Yes	No	0	8	8
246	R:R:I289	R:R:V293	1.54	No	No	0	7	5
247	R:R:K279	R:R:V231	1.52	No	No	0	5	5
248	R:R:F179	R:R:G180	1.51	No	No	0	4	6
249	R:R:L102	R:R:S103	1.5	No	No	0	5	3
250	R:R:L62	R:R:V84	1.49	No	No	0	7	6
251	R:R:L88	R:R:V84	1.49	No	No	0	6	6
252	R:R:L303	R:R:T304	1.47	No	Yes	0	5	5
253	R:R:I318	R:R:I322	1.47	No	No	0	1	3
254	R:R:I337	R:R:M286	1.46	No	No	0	8	8
255	R:R:A53	R:R:F332	1.39	No	No	0	4	6
256	R:R:A340	R:R:F341	1.39	No	No	0	6	6
257	R:R:L47	R:R:L98	1.38	Yes	No	0	6	6
258	R:R:F229	R:R:S233	1.32	No	No	0	5	5
259	R:R:F39	R:R:V38	1.31	No	No	0	2	2
260	R:R:R152	R:R:T150	1.29	No	No	0	5	5
261	R:R:E277	R:R:Q281	1.27	No	No	0	4	5
262	R:R:E280	R:R:Q281	1.27	No	No	0	7	5
263	R:R:L66	R:R:R69	1.21	No	No	0	4	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:?1	9.08875	8	2	0
2	R:R:I43	8.015	4	4	4
3	R:R:L47	4.6425	4	4	6
4	R:R:V61	2.485	4	0	9
5	R:R:F71	8.664	5	1	8
6	R:R:V74	6.3075	4	1	5
7	R:R:H76	5.865	4	1	9
8	R:R:N77	6.0175	4	1	4
9	R:R:D86	6.715	4	5	9
10	R:R:W107	6.66167	6	3	8
11	R:R:R111	6.725	4	7	4
12	R:R:W117	8.79	5	3	5
13	R:R:Y140	5.882	5	0	8
14	R:R:W141	6.6175	4	0	4
15	R:R:Y149	5.24833	6	1	8
16	R:R:R154	10.28	4	1	8
17	R:R:W181	7.896	5	0	7
18	R:R:E190	3.81	4	0	4
19	R:R:Y200	10.84	4	0	7
20	R:R:F209	7.8925	4	2	8
21	R:R:P212	6.3575	4	0	9
22	R:R:Y220	4.375	4	0	9
23	R:R:I291	3.105	4	0	8
24	R:R:W298	6.796	5	2	8
25	R:R:F302	8.44	5	2	6
26	R:R:T304	2.668	5	0	5
27	R:R:W325	4.5825	4	0	6
28	R:R:Y338	5.4875	4	8	9
29	R:R:Y345	7.16667	6	1	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:D121	80.8223	8.36	Yes	No	0	0	8
2	R:R:D121	R:R:Y328	88.7128	10.34	No	No	0	8	7
3	R:R:S97	R:R:Y328	82.2659	3.82	No	No	0	6	7
4	R:R:S97	R:R:W117	81.0912	4.94	No	Yes	0	6	5
5	R:R:H100	R:R:W117	40.351	12.7	No	Yes	3	5	5
6	R:R:H100	R:R:R105	42.5448	5.64	No	No	0	5	6
7	R:R:E101	R:R:R105	20.501	3.49	No	No	0	5	6
8	R:R:E101	R:R:W325	18.6753	6.54	No	Yes	0	5	6
9	R:R:L47	R:R:W325	26.1906	4.56	Yes	Yes	0	6	6
10	R:R:I43	R:R:L47	15.2502	5.71	Yes	Yes	4	4	6
11	R:R:R105	R:R:S321	20.317	3.95	No	No	0	6	5
12	R:R:S321	R:R:W325	18.6965	3.71	No	Yes	0	5	6
13	L:L:?1	R:R:F302	74.7647	9.64	Yes	Yes	2	0	6
14	R:R:F302	R:R:W298	84.3394	8.02	Yes	Yes	2	6	8
15	R:R:N330	R:R:W298	16.4886	9.04	No	Yes	0	9	8
16	R:R:C297	R:R:N330	14.7123	11.02	No	No	0	8	9
17	R:R:C297	R:R:F333	12.9219	2.79	No	No	0	8	6
18	R:R:F332	R:R:F333	11.1174	7.5	No	No	0	6	6
19	R:R:I129	R:R:W298	100	5.87	No	Yes	0	8	8
20	R:R:I129	R:R:P212	99.7099	3.39	No	Yes	0	8	9
21	R:R:P212	R:R:W130	98.613	13.51	Yes	No	0	9	6
22	R:R:T165	R:R:W130	97.8275	3.64	No	No	0	6	6
23	R:R:N131	R:R:T165	97.5515	4.39	No	No	0	7	6
24	R:R:M82	R:R:N131	62.4443	2.8	No	No	0	9	7
25	R:R:M82	R:R:N334	61.0926	8.41	No	No	0	9	9
26	R:R:D86	R:R:N334	14.7123	6.73	Yes	No	0	9	9
27	R:R:D121	R:R:V93	45.248	4.38	No	No	0	8	7
28	R:R:C120	R:R:V93	43.7053	3.42	No	No	0	5	7
29	R:R:C120	R:R:C124	42.2192	7.28	No	No	0	5	6
30	R:R:C124	R:R:L88	37.676	1.59	No	No	0	6	6
31	R:R:L88	R:R:V84	36.9542	1.49	No	No	0	6	6
32	R:R:L62	R:R:V84	36.7844	1.49	No	No	0	7	6
33	R:R:A83	R:R:L62	36.6145	3.15	No	No	0	9	7
34	R:R:A83	R:R:V61	36.473	1.7	No	Yes	0	9	9
35	R:R:T339	R:R:V61	35.2558	3.17	No	Yes	0	7	9
36	R:R:T339	R:R:Y345	35.178	3.75	No	Yes	0	7	8
37	R:R:H76	R:R:Y345	31.3566	8.71	Yes	Yes	1	9	8
38	R:R:N131	R:R:S81	75.5714	8.94	No	No	0	7	9
39	R:R:I162	R:R:S81	70.3913	3.1	No	No	0	8	9
40	R:R:I162	R:R:S158	61.4111	3.1	No	No	1	8	7
41	R:R:S158	R:R:V74	62.4584	3.23	No	Yes	1	7	5
42	R:R:P75	R:R:V74	14.4859	3.53	No	Yes	1	8	5
43	R:R:R154	R:R:V74	46.812	7.85	Yes	Yes	1	8	5
44	R:R:W107	R:R:W117	35.2275	13.12	Yes	Yes	3	8	5
45	R:R:E190	R:R:W107	24.8956	5.45	Yes	Yes	0	4	8
46	R:R:E190	R:R:R111	17.4227	5.82	Yes	Yes	0	4	4
47	R:R:N334	R:R:V132	48.291	2.96	No	No	0	9	8
48	R:R:V132	R:R:Y338	45.241	5.05	No	Yes	0	8	9
49	R:R:R139	R:R:Y338	15.1369	6.17	No	Yes	8	9	9
50	R:R:R139	R:R:Y220	13.6438	5.14	No	Yes	0	9	9
51	R:R:L290	R:R:Y338	26.9691	4.69	No	Yes	0	8	9
52	R:R:L290	R:R:Y220	13.9976	3.52	No	Yes	0	8	9
53	R:R:R154	R:R:Y149	64.5956	7.2	Yes	Yes	1	8	8
54	R:R:W141	R:R:Y149	43.9813	8.68	Yes	Yes	0	4	8
55	R:R:W141	R:R:Y140	31.7953	4.82	Yes	Yes	0	4	8
56	R:R:K222	R:R:Y140	23.6006	7.17	No	Yes	0	5	8
57	L:L:?1	R:R:S204	21.98	10.57	Yes	No	0	0	6
58	R:R:S204	R:R:Y200	20.3736	12.72	No	Yes	0	6	7
59	R:R:W181	R:R:Y200	12.1294	10.61	Yes	Yes	0	7	7
60	R:R:F209	R:R:I299	16.1135	6.28	Yes	No	0	8	6
61	R:R:I291	R:R:Y220	21.0105	4.84	Yes	Yes	0	8	9
62	R:R:K222	R:R:K225	19.5528	5.75	No	No	0	5	4
63	R:R:K225	R:R:W221	17.3873	6.96	No	No	0	4	1
64	R:R:W221	R:R:Y224	15.2077	1.93	No	No	0	1	6
65	R:R:K228	R:R:Y224	11.0183	8.36	No	No	0	5	6
66	R:R:I337	R:R:L290	12.3417	5.71	No	No	0	8	8
67	R:R:I299	R:R:P300	12.9573	3.39	No	No	0	6	9
68	L:L:?1	R:R:E305	13.1201	16.32	Yes	No	2	0	7
69	R:R:E305	R:R:F301	25.2565	16.32	No	No	0	7	7
70	R:R:F301	R:R:F323	22.2843	3.22	No	No	0	7	5
71	R:R:F323	R:R:P300	12.1152	4.33	No	No	0	5	9
72	R:R:F323	R:R:T304	30.3588	2.59	No	Yes	0	5	5
73	R:R:S308	R:R:T304	12.7733	3.2	No	Yes	0	3	5
74	R:R:P309	R:R:S308	10.2045	3.56	No	No	0	5	3
75	R:R:I315	R:R:T304	10.4097	3.04	No	Yes	0	4	5
76	R:R:H76	R:R:P75	35.4752	4.58	Yes	No	1	9	8
77	R:R:P75	R:R:R154	21.5413	12.97	No	Yes	1	8	8
78	R:R:E305	R:R:F302	13.5942	3.5	No	Yes	2	7	6
79	R:R:F209	R:R:W298	18.2011	4.01	Yes	Yes	2	8	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?1	R:R:D121	8.36	2	Yes	No	0	8	0	1
L:L:?1	R:R:V122	11.8	2	Yes	No	0	7	0	1
L:L:?1	R:R:C125	5.59	2	Yes	No	0	6	0	1
L:L:?1	R:R:T126	5.19	2	Yes	No	0	7	0	1
L:L:?1	R:R:V194	5.24	2	Yes	No	0	4	0	1
L:L:?1	R:R:S204	10.57	2	Yes	No	0	6	0	1
L:L:?1	R:R:F302	9.64	2	Yes	Yes	0	6	0	1
L:L:?1	R:R:E305	16.32	2	Yes	No	0	7	0	1
R:R:D121	R:R:V93	4.38	0	No	No	8	7	1	2
R:R:I118	R:R:V194	4.61	0	No	No	6	4	2	1
R:R:D121	R:R:Y328	10.34	0	No	No	8	7	1	2
R:R:V122	R:R:V194	3.21	2	No	No	7	4	1	1
R:R:A208	R:R:T126	3.36	0	No	No	7	7	2	1
R:R:S204	R:R:Y200	12.72	0	No	Yes	6	7	1	2
R:R:F302	R:R:T205	3.89	2	Yes	No	6	6	1	2
R:R:F209	R:R:W298	4.01	2	Yes	Yes	8	8	2	2
R:R:F209	R:R:F302	17.15	2	Yes	Yes	8	6	2	1
R:R:F302	R:R:W298	8.02	2	Yes	Yes	6	8	1	2
R:R:E305	R:R:F301	16.32	2	No	No	7	7	1	2
R:R:E305	R:R:F302	3.5	2	No	Yes	7	6	1	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	9W6W_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.1
Number of Linked Nodes	249
Number of Links	263
Number of Hubs	29
Number of Links mediated by Hubs	115
Number of Communities	8
Number of Nodes involved in Communities	39
Number of Links involved in Communities	46

Path Summary
Number Of Nodes in MetaPath	80
Number Of Links MetaPath	79
Number of Shortest Paths	34447
Length Of Smallest Path	3
Average Path Length	15.5288
Length of Longest Path	37
Minimum Path Strength	1.27
Average Path Strength	5.93929
Maximum Path Strength	16.32
Minimum Path Correlation	0.7
Average Path Correlation	0.925115
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	3.33333
Average % Of Corr. Nodes	46.1303
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	33.1294
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• binding • tetrapyrrole binding • heme binding • electron transfer activity • cation binding • transition metal ion binding • iron ion binding • ion binding • metal ion binding • small molecule binding • G protein-coupled amine receptor activity • G protein-coupled serotonin receptor activity • molecular transducer activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • Gi/o-coupled serotonin receptor activity • neurotransmitter receptor activity • serotonin receptor activity • electron transport chain • metabolic process • cellular process • generation of precursor metabolites and energy • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cell communication • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway
Gene Ontology	Biological Process	• electron transport chain • metabolic process • cellular process • generation of precursor metabolites and energy • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cell communication • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • signal transduction • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • developmental process • multicellular organismal process • head development • forebrain development • animal organ development • brain development • nervous system development • pallium development • multicellular organism development • central nervous system development • anatomical structure development • telencephalon development • hippocampus development • limbic system development • system development • trans-synaptic signaling • synaptic signaling • anterograde trans-synaptic signaling • cell-cell signaling • chemical synaptic transmission • response to lipid • response to chemical • response to estradiol • response to oxygen-containing compound • G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger • cellular anatomical structure • periplasmic space • somatodendritic compartment • cell body • perikaryon • neuronal cell body • cell periphery • plasma membrane • membrane • postsynaptic specialization membrane • postsynaptic specialization • synapse • synaptic membrane • postsynapse
Gene Ontology	Cellular Component	• cellular anatomical structure • periplasmic space • somatodendritic compartment • cell body • perikaryon • neuronal cell body • cell periphery • plasma membrane • membrane • postsynaptic specialization membrane • postsynaptic specialization • synapse • synaptic membrane • postsynapse • organelle • postsynaptic membrane • cell junction • plasma membrane region • cell projection • dendrite • dendritic tree • neuron projection • plasma membrane bounded cell projection • D2 dopamine receptor binding • protein binding • binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • enzyme regulator activity • adenylate cyclase inhibitor activity • cyclase regulator activity • molecular function inhibitor activity • cyclase inhibitor activity • molecular function regulator activity • enzyme inhibitor activity • adenylate cyclase regulator activity • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • cation binding • magnesium ion binding • metal ion binding • GDP binding • G protein-coupled serotonin receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • cell communication • G protein-coupled receptor signaling pathway • cellular process • signal transduction • neuropeptide signaling pathway • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • response to hormone • response to chemical • response to endogenous stimulus • response to peptide hormone • response to oxygen-containing compound • response to nitrogen compound • cell division • leukocyte migration • immune system process • mononuclear cell migration • lymphocyte migration • cell migration • T cell migration • cell motility • regulation of steroid biosynthetic process • regulation of cholesterol biosynthetic process • regulation of cholesterol metabolic process • steroid metabolic process • regulation of lipid metabolic process • sterol metabolic process • positive regulation of biological process • cholesterol metabolic process • lipid biosynthetic process • alcohol metabolic process • regulation of primary metabolic process • positive regulation of metabolic process • regulation of small molecule metabolic process • positive regulation of biosynthetic process • positive regulation of lipid metabolic process • small molecule metabolic process • steroid biosynthetic process • positive regulation of cellular process • regulation of biosynthetic process • secondary alcohol biosynthetic process • regulation of alcohol biosynthetic process • small molecule biosynthetic process • regulation of steroid metabolic process • cholesterol biosynthetic process • positive regulation of cholesterol biosynthetic process • primary metabolic process • secondary alcohol metabolic process • positive regulation of steroid biosynthetic process • biosynthetic process • sterol biosynthetic process • positive regulation of lipid biosynthetic process • regulation of sterol biosynthetic process • alcohol biosynthetic process • positive regulation of cholesterol metabolic process • positive regulation of steroid metabolic process • metabolic process • regulation of lipid biosynthetic process • positive regulation of small molecule metabolic process • regulation of metabolic process • positive regulation of alcohol biosynthetic process • positive regulation of sterol biosynthetic process • lipid metabolic process • cell surface receptor signaling pathway • response to cytokine • response to chemokine • cytokine-mediated signaling pathway • cellular response to chemokine • chemokine-mediated signaling pathway • response to peptide • cellular response to cytokine stimulus • multicellular organismal process • system process • relaxation of smooth muscle • regulation of system process • regulation of muscle system process • muscle system process • relaxation of muscle • positive regulation of relaxation of smooth muscle • positive regulation of relaxation of muscle • positive regulation of multicellular organismal process • regulation of multicellular organismal process • regulation of relaxation of smooth muscle • regulation of relaxation of muscle • negative regulation of protein transport • regulation of localization • establishment of protein localization • nitrogen compound transport • negative regulation of biological process • negative regulation of transport • localization • negative regulation of secretion • negative regulation of hormone secretion • negative regulation of secretion by cell • intracellular protein localization • regulation of biological quality • regulation of peptide hormone secretion • negative regulation of peptide hormone secretion • regulation of hormone levels • establishment of protein localization to extracellular region • negative regulation of establishment of protein localization • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • negative regulation of protein secretion • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • transport • negative regulation of signaling • hormone secretion • negative regulation of cell communication • protein localization to extracellular region • negative regulation of peptide secretion • peptide secretion • regulation of secretion by cell • secretion by cell • signal release • negative regulation of cellular process • negative regulation of protein localization • regulation of signaling • regulation of transport • secretion • regulation of peptide transport • regulation of establishment of protein localization • export from cell • cell-cell signaling • regulation of protein transport • peptide transport • negative regulation of insulin secretion • protein transport • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • hormone transport • regulation of cell communication • insulin secretion • adenylate cyclase-activating G protein-coupled receptor signaling pathway • regulation of cytoskeleton organization • regulation of cellular component organization • microtubule cytoskeleton organization • regulation of mitotic spindle organization • mitotic cell cycle • cellular component organization • cell cycle • cellular component organization or biogenesis • regulation of cell cycle • microtubule cytoskeleton organization involved in mitosis • spindle organization • cell cycle process • regulation of cell cycle process • regulation of microtubule-based process • regulation of spindle organization • regulation of organelle organization • mitotic spindle organization • organelle organization • mitotic cell cycle process • microtubule-based process • cytoskeleton organization • regulation of microtubule cytoskeleton organization • positive regulation of protein localization to cell periphery • protein localization to cell periphery • positive regulation of protein localization to cell cortex • regulation of protein localization to cell periphery • regulation of protein localization to cell cortex • positive regulation of protein localization • protein localization to cell cortex • response to ketone • response to prostaglandin • response to lipid • response to alcohol • response to prostaglandin E • cellular response to forskolin • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to alcohol • response to forskolin • cellular response to lipid • cellular response to ketone • midbody • membrane-bounded organelle • intracellular anatomical structure • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • intracellular membrane-bounded organelle • nucleolus • intracellular organelle lumen • intracellular organelle • organelle lumen • membraneless organelle • nuclear lumen • cell cortex • cytoplasm • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular region • extracellular space • vesicle • extracellular membrane-bounded organelle • centrosome • microtubule organizing center • cytoskeleton • microtubule cytoskeleton • centriolar satellite • cytosol • sperm principal piece • cilium • 9+2 motile cilium • sperm flagellum • motile cilium • nucleoplasm • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • organelle membrane • lysosome • Golgi apparatus • endomembrane system • ciliary basal body • G-protein beta-subunit binding • fibroblast proliferation • cell population proliferation • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • cellular response to monoamine stimulus • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to hormone stimulus • enzyme binding • GTPase binding • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • photoreceptor disc membrane • photoreceptor outer segment • photoreceptor cell cilium
SCOP2	Domain Identifier	• Ras-like P-loop GTPases • Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Ras-like P-loop GTPases • Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	8K3
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	8K3
Name	3-(2-azanylethyl)-1H-indole-5-carboxamide
Synonyms
Identifier
Formula	C11 H13 N3 O
Molecular Weight	203.24
SMILES
PubChem	1809
Formal Charge	0
Total Atoms	28
Total Chiral Atoms	0
Total Bonds	29
Total Aromatic Bonds	10


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P47898
Sequence	>9W6W_nogp_Chain_R V F G V L I L T L L G F L V A A T F A W N L L V L A T I L R V R T F H R V P H N L V A S M A V S D V L V A A L V M P L S L V H E L S G R R W Q L G R R L C Q L W I A C D V L C C T A S I W N V T A I A L D R Y W S I T R H M E Y T L R T R K C V S N V M I A L T W A L S A V I S L A P L L F G W G E T Y S E G S E E C Q V S R E P S Y A V F S T V G A F Y L P L C V V L F V Y W K I Y K A A K F R V G S R E Q K E Q R A A L M V G I L I G V F V L C W I P F F L T E L I S P L C S C D I P A I W K S I F L W L G Y S N S F F N P L I Y T A F N K N Y N S A F K N F F Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	7UM4	A	Amine	5-Hydroxytryptamine	5-HT_5A	Homo sapiens	AS2674723	-	-	2.8	2022-07-20	doi.org/10.1038/s41594-022-00796-6
	7UM5	A	Amine	5-Hydroxytryptamine	5-HT_5A	Homo sapiens	5-CT	-	chim(NtGi1-Go)/β1/γ2	2.73	2022-07-20	doi.org/10.1038/s41594-022-00796-6
	7UM5 (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_5A	Homo sapiens	5-CT	-		2.73	2022-07-20	doi.org/10.1038/s41594-022-00796-6
	7UM6	A	Amine	5-Hydroxytryptamine	5-HT_5A	Homo sapiens	Lisuride	-	chim(NtGi1-Go)/β1/γ2	2.79	2022-07-20	doi.org/10.1038/s41594-022-00796-6
	7UM6 (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_5A	Homo sapiens	Lisuride	-		2.79	2022-07-20	doi.org/10.1038/s41594-022-00796-6
	7UM7	A	Amine	5-Hydroxytryptamine	5-HT_5A	Homo sapiens	Methylergometrine	-	chim(NtGi1-Go)/β1/γ2	2.75	2022-07-20	doi.org/10.1038/s41594-022-00796-6
	7UM7 (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_5A	Homo sapiens	Methylergometrine	-		2.75	2022-07-20	doi.org/10.1038/s41594-022-00796-6
	7X5H	A	Amine	5-Hydroxytryptamine	5-HT_5A	Homo sapiens	5-CT	-	Gi1/β1/γ2	3.1	2022-09-14	doi.org/10.1038/s41421-022-00412-3
	7X5H (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_5A	Homo sapiens	5-CT	-		3.1	2022-09-14	doi.org/10.1038/s41421-022-00412-3
	9W6W	A	Amine	5-Hydroxytryptamine	5-HT_5A	Homo sapiens	5-CT	-	Gi1/β1/γ2	3.13	2025-11-26	10.1186/s43556-025-00359-3
	9W6W (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_5A	Homo sapiens	5-CT	-		3.13	2025-11-26	10.1186/s43556-025-00359-3

2D representation of the interactions of this orthosteric/allosteric ligand.

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

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