psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:T22	R:R:V23	3.17	No	No	0	1	1
2	R:R:T22	R:R:T25	3.14	No	No	0	1	2
3	R:R:E86	R:R:Y27	3.37	No	No	0	3	3
4	R:R:V255	R:R:Y27	5.05	No	No	0	1	3
5	R:R:L30	R:R:S259	9.01	No	No	0	5	3
6	R:R:C40	R:R:F36	5.59	No	No	0	6	5
7	R:R:S266	R:R:T37	6.4	No	No	0	6	7
8	R:R:S270	R:R:T37	4.8	No	No	0	8	7
9	R:R:C38	R:R:L76	4.76	No	No	0	6	7
10	R:R:C38	R:R:M79	3.24	No	Yes	0	6	5
11	R:R:A80	R:R:C38	3.61	No	No	0	6	6
12	R:R:G41	R:R:S270	3.71	No	No	0	9	8
13	R:R:F77	R:R:M42	3.73	No	No	0	4	7
14	R:R:D72	R:R:N45	6.73	Yes	No	0	9	9
15	R:R:N45	R:R:P273	9.77	No	No	0	9	9
16	R:R:A69	R:R:V48	3.39	No	No	0	9	9
17	R:R:F277	R:R:V48	7.87	Yes	No	0	7	9
18	R:R:L51	R:R:W50	4.56	No	No	0	7	6
19	R:R:F277	R:R:L51	3.65	Yes	No	0	7	7
20	R:R:C62	R:R:L52	9.52	No	Yes	0	8	8
21	R:R:L52	R:R:L66	5.54	Yes	No	0	8	8
22	R:R:F277	R:R:L52	4.87	Yes	Yes	0	7	8
23	R:R:M56	R:R:R55	3.72	Yes	No	0	7	6
24	R:R:C62	R:R:M56	3.24	No	Yes	0	8	7
25	R:R:M56	R:R:R283	6.2	Yes	No	0	7	6
26	R:R:M56	R:R:S284	4.6	Yes	No	0	7	5
27	R:R:H57	R:R:I63	6.63	No	No	0	6	7
28	R:R:R283	R:R:R58	7.46	No	No	0	6	7
29	R:R:N59	R:R:P60	4.89	No	Yes	1	8	7
30	R:R:F61	R:R:N59	3.62	Yes	No	1	8	8
31	R:R:C62	R:R:N59	4.72	No	No	0	8	8
32	R:R:F61	R:R:P60	4.33	Yes	Yes	1	8	7
33	R:R:F133	R:R:P60	5.78	Yes	Yes	1	7	7
34	R:R:P60	R:R:R137	5.76	Yes	Yes	1	7	9
35	R:R:F61	R:R:Q122	14.05	Yes	Yes	1	8	9
36	R:R:F61	R:R:S126	5.28	Yes	No	1	8	8
37	R:R:F133	R:R:F61	7.5	Yes	Yes	1	7	8
38	R:R:I63	R:R:S142	4.64	No	No	0	7	9
39	R:R:A118	R:R:Y64	4	No	Yes	0	8	8
40	R:R:I119	R:R:Y64	3.63	No	Yes	0	9	8
41	R:R:Q122	R:R:Y64	12.4	Yes	Yes	0	9	8
42	R:R:S142	R:R:Y64	11.45	No	Yes	0	9	8
43	R:R:V145	R:R:Y64	8.83	No	Yes	0	6	8
44	R:R:C146	R:R:Y64	4.03	No	Yes	0	7	8
45	R:R:L115	R:R:N67	4.12	No	No	0	7	9
46	R:R:C146	R:R:N67	12.6	No	No	0	7	9
47	R:R:N67	R:R:W150	5.65	No	Yes	0	9	9
48	R:R:D72	R:R:L68	5.43	Yes	Yes	2	9	9
49	R:R:L115	R:R:L68	4.15	No	Yes	0	7	9
50	R:R:L116	R:R:L68	5.54	No	Yes	2	9	9
51	R:R:L68	R:R:N272	5.49	Yes	Yes	2	9	9
52	R:R:D72	R:R:S269	10.31	Yes	No	0	9	9
53	R:R:D72	R:R:N272	6.73	Yes	Yes	2	9	9
54	R:R:A108	R:R:L74	4.73	No	No	0	7	6
55	R:R:F75	R:R:M105	6.22	Yes	No	0	6	4
56	R:R:F75	R:R:Y109	5.16	Yes	Yes	3	6	8
57	R:R:F75	R:R:S265	3.96	Yes	No	3	6	8
58	R:R:F75	R:R:S269	7.93	Yes	No	0	6	9
59	R:R:L76	R:R:S269	6.01	No	No	0	7	9
60	R:R:F77	R:R:S81	5.28	No	No	0	4	5
61	R:R:L104	R:R:S78	4.5	No	No	0	5	5
62	R:R:M105	R:R:S78	4.6	No	No	0	4	5
63	R:R:M105	R:R:M79	7.22	No	Yes	0	4	5
64	R:R:M79	R:R:R262	6.2	Yes	Yes	0	5	4
65	R:R:M79	R:R:S266	4.6	Yes	No	0	5	6
66	R:R:M101	R:R:S81	3.07	No	No	0	4	5
67	R:R:E86	R:R:T82	4.23	No	No	0	3	3
68	R:R:M101	R:R:T82	3.01	No	No	0	4	3
69	R:R:L83	R:R:R262	6.07	No	Yes	0	6	4
70	R:R:H98	R:R:L85	6.43	No	No	0	5	3
71	R:R:E86	R:R:R262	5.82	No	Yes	0	3	4
72	R:R:Q88	R:R:T87	5.67	No	No	0	4	4
73	R:R:P89	R:R:Q88	3.16	No	No	0	3	4
74	R:R:L90	R:R:T94	7.37	No	No	0	1	1
75	R:R:N92	R:R:T93	4.39	No	No	0	5	2
76	R:R:T93	R:R:T94	3.14	No	No	0	2	1
77	R:R:D95	R:R:K166	9.68	No	Yes	0	1	3
78	R:R:F167	R:R:K96	13.65	No	No	0	1	1
79	R:R:H98	R:R:K102	5.24	No	Yes	0	5	3
80	R:R:E99	R:R:K102	5.4	Yes	Yes	4	5	3
81	R:R:E99	R:R:R103	5.82	Yes	Yes	4	5	4
82	R:R:E99	R:R:S165	8.62	Yes	No	4	5	3
83	R:R:E99	R:R:K166	10.8	Yes	Yes	0	5	3
84	R:R:K102	R:R:R103	3.71	Yes	Yes	4	3	4
85	R:R:K102	R:R:Y106	3.58	Yes	No	0	3	3
86	R:R:R103	R:R:S161	7.91	Yes	No	0	4	3
87	R:R:R103	R:R:S165	6.59	Yes	No	4	4	3
88	R:R:W241	R:R:Y106	27.97	No	No	0	4	3
89	R:R:F107	R:R:W150	5.01	No	Yes	0	5	9
90	R:R:F107	R:R:L154	6.09	No	No	0	5	4
91	R:R:F107	R:R:N157	12.08	No	No	0	5	7
92	R:R:L113	R:R:Y109	14.07	No	Yes	0	8	8
93	R:R:L237	R:R:Y109	9.38	Yes	Yes	3	5	8
94	R:R:S238	R:R:Y109	3.82	Yes	Yes	0	7	8
95	R:R:W241	R:R:Y109	3.86	No	Yes	3	4	8
96	R:R:S265	R:R:Y109	5.09	No	Yes	3	8	8
97	R:R:C153	R:R:T110	5.07	No	Yes	0	8	6
98	R:R:N157	R:R:T110	4.39	No	Yes	0	7	6
99	R:R:Q182	R:R:T110	7.09	No	Yes	5	6	6
100	R:R:I186	R:R:T110	3.04	No	Yes	5	7	6
101	R:R:V111	R:R:W150	15.94	No	Yes	0	7	9
102	R:R:C153	R:R:V111	5.12	No	No	0	8	7
103	R:R:L113	R:R:S234	4.5	No	No	0	8	7
104	R:R:L149	R:R:S114	6.01	No	No	0	7	7
105	R:R:C153	R:R:S114	3.44	No	No	0	8	7
106	R:R:L116	R:R:N272	9.61	No	Yes	2	9	9
107	R:R:L116	R:R:Y276	4.69	No	Yes	2	9	9
108	R:R:L190	R:R:T117	8.84	No	No	0	8	8
109	R:R:T117	R:R:V193	3.17	No	No	0	8	6
110	R:R:M194	R:R:T117	3.01	Yes	No	0	8	8
111	R:R:I119	R:R:Y276	7.25	No	Yes	0	9	9
112	R:R:M194	R:R:S120	7.67	Yes	No	6	8	9
113	R:R:S120	R:R:S198	3.26	No	No	6	9	8
114	R:R:S197	R:R:T121	6.4	No	No	0	8	6
115	R:R:F133	R:R:Q122	7.03	Yes	Yes	1	7	9
116	R:R:Q122	R:R:R137	3.5	Yes	Yes	1	9	9
117	R:R:R123	R:R:Y276	7.2	No	Yes	0	9	9
118	R:R:C124	R:R:L128	3.17	No	No	0	8	6
119	R:R:C124	R:R:S197	3.44	No	No	0	8	8
120	R:R:C124	R:R:T200	3.38	No	No	0	8	5
121	R:R:S126	R:R:V127	3.23	No	No	0	8	8
122	R:R:F133	R:R:S126	7.93	Yes	No	1	7	8
123	R:R:L201	R:R:V127	4.47	No	No	0	8	8
124	R:R:F129	R:R:L128	6.09	No	No	0	5	6
125	R:R:L128	R:R:W204	11.39	No	No	0	6	6
126	R:R:H136	R:R:W132	5.29	No	No	0	6	6
127	R:R:R137	R:R:W132	10	Yes	No	0	9	6
128	R:R:F133	R:R:R137	9.62	Yes	Yes	1	7	9
129	R:R:C135	R:R:H136	7.37	No	No	0	7	6
130	R:R:L141	R:R:R137	3.64	No	Yes	0	5	9
131	R:R:R137	R:R:S142	6.59	Yes	No	0	9	9
132	R:R:L141	R:R:P138	6.57	No	No	0	5	8
133	R:R:H140	R:R:R139	21.44	No	No	0	5	5
134	R:R:H140	R:R:W144	3.17	No	No	0	5	5
135	R:R:L141	R:R:W144	6.83	No	No	0	5	5
136	R:R:M156	R:R:Q182	6.8	No	No	0	4	6
137	R:R:T160	R:R:V178	4.76	No	No	0	4	4
138	R:R:F163	R:R:R174	9.62	No	No	0	4	1
139	R:R:F163	R:R:V178	6.55	No	No	0	4	4
140	R:R:C164	R:R:C175	7.28	No	No	0	6	8
141	R:R:F170	R:R:K166	13.65	No	Yes	0	1	3
142	R:R:K169	R:R:N171	5.6	No	No	0	1	5
143	R:R:N171	R:R:R174	14.46	No	No	0	5	1
144	R:R:D173	R:R:R174	7.15	No	No	0	3	1
145	R:R:F176	R:R:R177	5.34	Yes	No	0	2	3
146	R:R:F176	R:R:M180	9.95	Yes	No	8	2	3
147	R:R:F176	R:R:Y245	4.13	Yes	Yes	8	2	4
148	R:R:F176	R:R:W246	3.01	Yes	No	0	2	4
149	R:R:D179	R:R:Y245	8.05	No	Yes	0	3	4
150	R:R:F242	R:R:M180	3.73	No	No	0	5	3
151	R:R:M180	R:R:Y245	3.59	No	Yes	8	3	4
152	R:R:I186	R:R:Q182	5.49	No	No	5	7	6
153	R:R:I186	R:R:S238	4.64	No	Yes	0	7	7
154	R:R:M187	R:R:T191	3.01	No	Yes	0	7	5
155	R:R:M187	R:R:S238	3.07	No	Yes	0	7	7
156	R:R:G188	R:R:P192	4.06	No	No	0	5	5
157	R:R:P192	R:R:T191	3.5	No	Yes	0	5	5
158	R:R:F230	R:R:T191	3.89	No	Yes	0	9	5
159	R:R:L235	R:R:T191	5.9	No	Yes	0	6	5
160	R:R:M194	R:R:S198	3.07	Yes	No	6	8	8
161	R:R:F230	R:R:M194	9.95	No	Yes	0	9	8
162	R:R:L231	R:R:T195	4.42	No	No	0	8	4
163	R:R:S198	R:R:V227	3.23	No	No	0	8	8
164	R:R:F202	R:R:F220	17.15	No	Yes	0	5	5
165	R:R:R207	R:R:W204	12	No	No	7	5	6
166	R:R:S208	R:R:W204	4.94	No	No	7	5	6
167	R:R:P216	R:R:V205	3.53	No	No	0	7	6
168	R:R:L219	R:R:V205	11.92	No	No	0	7	6
169	R:R:Q210	R:R:R206	9.35	No	No	9	5	5
170	R:R:F220	R:R:R206	4.28	Yes	No	9	5	5
171	R:R:R207	R:R:S208	9.22	No	No	7	5	5
172	R:R:R213	R:R:S209	6.59	No	No	0	5	7
173	R:R:Q210	R:R:Q215	15.36	No	No	0	5	5
174	R:R:F220	R:R:Q210	7.03	Yes	No	9	5	5
175	R:R:Q211	R:R:W212	7.67	No	No	0	5	3
176	R:R:V222	R:R:V279	4.81	No	No	10	7	7
177	R:R:S226	R:R:V227	3.23	No	No	0	7	8
178	R:R:S268	R:R:V229	3.23	Yes	No	0	9	7
179	R:R:F230	R:R:L231	3.65	No	No	0	9	8
180	R:R:C233	R:R:S268	3.44	No	Yes	0	7	9
181	R:R:S234	R:R:S268	6.52	No	Yes	0	7	9
182	R:R:P236	R:R:S261	3.56	No	No	0	9	5
183	R:R:P236	R:R:S264	5.34	No	No	0	9	7
184	R:R:L237	R:R:W241	5.69	Yes	No	3	5	4
185	R:R:L237	R:R:S261	4.5	Yes	No	0	5	5
186	R:R:L237	R:R:S265	6.01	Yes	No	3	5	8
187	R:R:L244	R:R:Y240	12.89	No	Yes	0	3	3
188	R:R:C257	R:R:Y240	5.38	No	Yes	0	4	3
189	R:R:F258	R:R:Y240	12.38	No	Yes	0	3	3
190	R:R:S261	R:R:Y240	3.82	No	Yes	0	5	3
191	R:R:F242	R:R:W246	4.01	No	No	0	5	4
192	R:R:L244	R:R:Q254	3.99	No	No	0	3	2
193	R:R:L247	R:R:L249	4.15	No	No	0	3	3
194	R:R:L249	R:R:P250	3.28	No	No	0	3	1
195	R:R:M253	R:R:P250	6.71	No	No	0	1	1
196	R:R:P251	R:R:Q254	4.74	No	No	0	2	2
197	R:R:F258	R:R:R262	18.17	No	Yes	0	3	4
198	R:R:N272	R:R:S268	4.47	Yes	Yes	0	9	9
199	R:R:N272	R:R:Y276	5.81	Yes	Yes	2	9	9
200	R:R:I275	R:R:V274	3.07	No	No	0	8	6
201	R:R:I275	R:R:Y276	6.04	No	Yes	0	8	9
202	R:R:S281	R:R:S284	4.89	No	No	0	7	5
203	R:R:H285	R:R:S281	5.58	No	No	0	4	7
204	R:R:L83	R:R:S31	3	No	No	0	6	3
205	R:R:L74	R:R:S78	3	No	No	0	6	5
206	R:R:L168	R:R:S162	3	No	No	0	1	3
207	R:R:L256	R:R:S259	3	Yes	No	0	2	3
208	R:R:L256	R:R:V23	2.98	Yes	No	0	2	1
209	R:R:L185	R:R:V189	2.98	No	No	0	5	5
210	R:R:L201	R:R:V223	2.98	No	No	0	8	8
211	R:R:L249	R:R:V243	2.98	No	No	0	3	5
212	R:R:I239	R:R:M187	2.92	No	No	0	6	7
213	R:R:F220	R:R:P216	2.89	Yes	No	0	5	7
214	R:R:K166	R:R:K96	2.87	Yes	No	0	3	1
215	R:R:I49	R:R:L66	2.85	No	No	0	7	8
216	R:R:I65	R:R:L52	2.85	No	Yes	0	8	8
217	R:R:I232	R:R:L228	2.85	No	No	0	5	6
218	R:R:L73	R:R:M42	2.83	No	No	0	7	7
219	R:R:L260	R:R:L30	2.77	No	No	0	4	5
220	R:R:L148	R:R:L152	2.77	No	No	0	5	6
221	R:R:A183	R:R:F242	2.77	No	No	0	5	5
222	R:R:D95	R:R:L90	2.71	No	No	0	1	1
223	R:R:C175	R:R:Y245	2.69	No	Yes	0	8	4
224	R:R:A71	R:R:W150	2.59	No	Yes	0	9	9
225	R:R:F129	R:R:L125	2.44	No	No	0	5	6
226	R:R:F277	R:R:L278	2.44	Yes	No	0	7	7
227	R:R:H24	R:R:Y27	2.18	No	No	0	1	3
228	R:R:C40	R:R:G41	1.96	No	No	0	6	9
229	R:R:C146	R:R:G147	1.96	No	No	0	7	5
230	R:R:A43	R:R:G44	1.95	No	No	0	5	9
231	R:R:A71	R:R:G112	1.95	No	No	0	9	9
232	R:R:P250	R:R:P251	1.95	No	No	0	1	2
233	R:R:G280	R:R:V279	1.84	No	No	0	9	7
234	R:R:P216	R:R:S209	1.78	No	No	0	7	7
235	R:R:G44	R:R:M47	1.75	No	No	0	9	6
236	R:R:A34	R:R:S266	1.71	No	No	0	6	6
237	R:R:G53	R:R:L66	1.71	No	No	0	6	8
238	R:R:A183	R:R:S238	1.71	No	Yes	0	5	7
239	R:R:C233	R:R:V267	1.71	No	No	0	7	5
240	R:R:C135	R:R:I131	1.64	No	No	0	7	7
241	R:R:S120	R:R:S197	1.63	No	No	0	9	8
242	R:R:A70	R:R:I49	1.62	No	No	0	5	7
243	R:R:A80	R:R:M35	1.61	No	No	0	6	4
244	R:R:V221	R:R:V222	1.6	No	No	0	6	7
245	R:R:T25	R:R:V29	1.59	No	No	0	2	4
246	R:R:A26	R:R:L256	1.58	No	Yes	0	3	2
247	R:R:A34	R:R:L263	1.58	No	No	0	6	5
248	R:R:M35	R:R:S84	1.53	No	No	0	4	5
249	R:R:M156	R:R:T160	1.51	No	No	0	4	4
250	R:R:L73	R:R:S46	1.5	No	No	0	7	6
251	R:R:L33	R:R:V29	1.49	No	No	0	5	4
252	R:R:L190	R:R:V189	1.49	No	No	0	8	5
253	R:R:L199	R:R:V203	1.49	No	No	0	5	5
254	R:R:L201	R:R:V205	1.49	No	No	0	8	6
255	R:R:L219	R:R:V223	1.49	No	No	0	7	8
256	R:R:L256	R:R:V255	1.49	Yes	No	0	2	1
257	R:R:F129	R:R:P130	1.44	No	No	0	5	9
258	R:R:Q215	R:R:T217	1.42	No	No	0	5	5
259	R:R:L39	R:R:M42	1.41	No	No	0	6	7
260	R:R:L51	R:R:M47	1.41	No	No	0	7	6
261	R:R:L224	R:R:L228	1.38	No	No	0	5	6
262	R:R:E252	R:R:M253	1.35	No	No	0	2	1
263	R:R:R218	R:R:V222	1.31	No	No	10	7	7
264	R:R:R218	R:R:V279	1.31	No	No	10	7	7
265	R:R:F167	R:R:L168	1.22	No	No	0	1	1
266	R:R:F202	R:R:L224	1.22	No	No	0	5	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:L52	5.695	4	0	8
2	R:R:M56	4.44	4	0	7
3	R:R:P60	5.19	4	1	7
4	R:R:F61	6.956	5	1	8
5	R:R:Y64	7.39	6	0	8
6	R:R:L68	5.1525	4	2	9
7	R:R:D72	7.3	4	2	9
8	R:R:F75	5.8175	4	3	6
9	R:R:M79	5.315	4	0	5
10	R:R:E99	7.66	4	4	5
11	R:R:K102	4.4825	4	4	3
12	R:R:R103	6.0075	4	4	4
13	R:R:Y109	6.89667	6	3	8
14	R:R:T110	4.8975	4	5	6
15	R:R:Q122	9.245	4	1	9
16	R:R:F133	7.572	5	1	7
17	R:R:R137	6.51833	6	1	9
18	R:R:W150	7.2975	4	0	9
19	R:R:K166	9.25	4	0	3
20	R:R:F176	5.6075	4	8	2
21	R:R:T191	4.075	4	0	5
22	R:R:M194	5.925	4	6	8
23	R:R:F220	7.8375	4	9	5
24	R:R:L237	6.395	4	3	5
25	R:R:S238	3.31	4	0	7
26	R:R:Y240	8.6175	4	0	3
27	R:R:Y245	4.615	4	8	4
28	R:R:L256	2.2625	4	0	2
29	R:R:R262	9.065	4	0	4
30	R:R:S268	4.415	4	0	9
31	R:R:N272	6.422	5	2	9
32	R:R:Y276	6.198	5	2	9
33	R:R:F277	4.7075	4	0	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:E86	R:R:Y27	16.435	3.37	No	No	0	3	3
2	R:R:V255	R:R:Y27	14.1189	5.05	No	No	0	1	3
3	R:R:L256	R:R:V255	13.0391	1.49	Yes	No	0	2	1
4	R:R:M79	R:R:R262	28.9783	6.2	Yes	Yes	0	5	4
5	R:R:E86	R:R:R262	27.0634	5.82	No	Yes	0	3	4
6	R:R:C38	R:R:M79	15.1334	3.24	No	Yes	0	6	5
7	R:R:C38	R:R:L76	16.0468	4.76	No	No	0	6	7
8	R:R:E86	R:R:T82	10.2988	4.23	No	No	0	3	3
9	R:R:D72	R:R:S269	64.6865	10.31	Yes	No	0	9	9
10	R:R:F75	R:R:S269	51.2103	7.93	Yes	No	0	6	9
11	R:R:F75	R:R:M105	27.8495	6.22	Yes	No	0	6	4
12	R:R:M105	R:R:M79	25.1093	7.22	No	Yes	0	4	5
13	R:R:L76	R:R:S269	16.5851	6.01	No	No	0	7	9
14	R:R:F277	R:R:L52	13.3262	4.87	Yes	Yes	0	7	8
15	R:R:C62	R:R:L52	21.9188	9.52	No	Yes	0	8	8
16	R:R:C62	R:R:N59	33.0104	4.72	No	No	0	8	8
17	R:R:F61	R:R:N59	33.1931	3.62	Yes	No	1	8	8
18	R:R:F61	R:R:Q122	58.4589	14.05	Yes	Yes	1	8	9
19	R:R:Q122	R:R:Y64	100	12.4	Yes	Yes	0	9	8
20	R:R:I119	R:R:Y64	83.5976	3.63	No	Yes	0	9	8
21	R:R:I119	R:R:Y276	84.0739	7.25	No	Yes	0	9	9
22	R:R:N272	R:R:Y276	85.9268	5.81	Yes	Yes	2	9	9
23	R:R:D72	R:R:N272	59.8845	6.73	Yes	Yes	2	9	9
24	R:R:C62	R:R:M56	10.4097	3.24	No	Yes	0	8	7
25	R:R:S142	R:R:Y64	18.102	11.45	No	Yes	0	9	8
26	R:R:F133	R:R:Q122	26.5805	7.03	Yes	Yes	1	7	9
27	R:R:Q122	R:R:R137	14.0699	3.5	Yes	Yes	1	9	9
28	R:R:R137	R:R:S142	14.6898	6.59	Yes	No	0	9	9
29	R:R:F61	R:R:S126	25.8302	5.28	Yes	No	1	8	8
30	R:R:F133	R:R:S126	25.093	7.93	Yes	No	1	7	8
31	R:R:C146	R:R:N67	39.2184	12.6	No	No	0	7	9
32	R:R:N67	R:R:W150	39.463	5.65	No	Yes	0	9	9
33	R:R:F75	R:R:Y109	42.6502	5.16	Yes	Yes	3	6	8
34	R:R:K102	R:R:Y106	22.7116	3.58	Yes	No	0	3	3
35	R:R:W241	R:R:Y106	23.8729	27.97	No	No	0	4	3
36	R:R:W241	R:R:Y109	22.1635	3.86	No	Yes	3	4	8
37	R:R:L237	R:R:S261	21.0282	4.5	Yes	No	0	5	5
38	R:R:S261	R:R:Y240	17.2408	3.82	No	Yes	0	5	3
39	R:R:E99	R:R:K166	13.7437	10.8	Yes	Yes	0	5	3
40	R:R:E99	R:R:K102	15.9261	5.4	Yes	Yes	4	5	3
41	R:R:F107	R:R:N157	19.5276	12.08	No	No	0	5	7
42	R:R:N157	R:R:T110	19.57	4.39	No	Yes	0	7	6
43	R:R:I186	R:R:T110	33.118	3.04	No	Yes	5	7	6
44	R:R:I186	R:R:S238	37.4274	4.64	No	Yes	0	7	7
45	R:R:S238	R:R:Y109	49.2595	3.82	Yes	Yes	0	7	8
46	R:R:L113	R:R:Y109	28.9554	14.07	No	Yes	0	8	8
47	R:R:C153	R:R:T110	20.1409	5.07	No	Yes	0	8	6
48	R:R:C153	R:R:V111	19.906	5.12	No	No	0	8	7
49	R:R:L113	R:R:S234	28.8282	4.5	No	No	0	8	7
50	R:R:F230	R:R:M194	37.3328	9.95	No	Yes	0	9	8
51	R:R:F230	R:R:T191	42.4512	3.89	No	Yes	0	9	5
52	R:R:M187	R:R:T191	49.1844	3.01	No	Yes	0	7	5
53	R:R:M187	R:R:S238	52.5119	3.07	No	Yes	0	7	7
54	R:R:M194	R:R:S120	21.5078	7.67	Yes	No	6	8	9
55	R:R:S120	R:R:S197	19.8473	1.63	No	No	0	9	8
56	R:R:C124	R:R:S197	16.2719	3.44	No	No	0	8	8
57	R:R:C124	R:R:L128	12.6705	3.17	No	No	0	8	6
58	R:R:S126	R:R:V127	48.2254	3.23	No	No	0	8	8
59	R:R:L201	R:R:V127	45.4981	4.47	No	No	0	8	8
60	R:R:R137	R:R:W132	11.2449	10	Yes	No	0	9	6
61	R:R:L141	R:R:R137	13.8644	3.64	No	Yes	0	5	9
62	R:R:F242	R:R:M180	12.7422	3.73	No	No	0	5	3
63	R:R:A183	R:R:F242	19.6581	2.77	No	No	0	5	5
64	R:R:A183	R:R:S238	21.436	1.71	No	Yes	0	5	7
65	R:R:F202	R:R:F220	10.9676	17.15	No	Yes	0	5	5
66	R:R:F220	R:R:P216	24.8907	2.89	Yes	No	0	5	7
67	R:R:P216	R:R:V205	32.8929	3.53	No	No	0	7	6
68	R:R:L201	R:R:V205	38.0733	1.49	No	No	0	8	6
69	R:R:S234	R:R:S268	28.7532	6.52	No	Yes	0	7	9
70	R:R:N272	R:R:S268	29.5753	4.47	Yes	Yes	0	9	9
71	R:R:L244	R:R:Y240	13.6883	12.89	No	Yes	0	3	3
72	R:R:L244	R:R:Q254	12.1615	3.99	No	No	0	3	2
73	R:R:P251	R:R:Q254	10.886	4.74	No	No	0	2	2
74	R:R:L237	R:R:Y109	14.1874	9.38	Yes	Yes	3	5	8
75	R:R:F107	R:R:W150	19.5081	5.01	No	Yes	0	5	9
76	R:R:V111	R:R:W150	19.893	15.94	No	Yes	0	7	9
77	R:R:C146	R:R:Y64	38.181	4.03	No	Yes	0	7	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 7Y15_nogp

PDB Summary
PDB	7Y15_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.01
Number of Linked Nodes	243
Number of Links	266
Number of Hubs	33
Number of Links mediated by Hubs	118
Number of Communities	10
Number of Nodes involved in Communities	39
Number of Links involved in Communities	49

Path Summary
Number Of Nodes in MetaPath	78
Number Of Links MetaPath	77
Number of Shortest Paths	56689
Length Of Smallest Path	3
Average Path Length	16.2936
Length of Longest Path	31
Minimum Path Strength	1.3
Average Path Strength	6.18761
Maximum Path Strength	16.83
Minimum Path Correlation	0.7
Average Path Correlation	0.920932
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	3.7037
Average % Of Corr. Nodes	40.0802
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	42.664
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain • WD40 repeat-like • Ras-like P-loop GTPases
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain • WD40 repeat-like • Ras-like P-loop GTPases
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q8TDS7
Sequence	>7Y15_nogp_Chain_R T V H T A Y L V L S S L A M F T C L C G M A G N S M V I W L L G F R M H R N P F C I Y I L N L A A A D L L F L F S M A S T L S L E T Q P L V N T T D K V H E L M K R L M Y F A Y T V G L S L L T A I S T Q R C L S V L F P I W F K C H R P R H L S A W V C G L L W T L C L L M N G L T S S F C S K F L K F N E D R C F R V D M V Q A A L I M G V L T P V M T L S S L T L F V W V R R S S Q Q W R R Q P T R L F V V V L A S V L V F L I C S L P L S I Y W F V L Y W L S L P P E M Q V L C F S L S R L S S S V S S S A N P V I Y F L V G S R R S H Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	7Y12	A	Orphan	Orphan	MRGPRD	Homo sapiens	β-Alanine	-	Gi1/β1/γ2	3.1	2022-07-20	doi.org/10.1038/s42003-022-03668-3
	7Y12 (No Gprot)	A	Orphan	Orphan	MRGPRD	Homo sapiens	β-Alanine	-		3.1	2022-07-20	doi.org/10.1038/s42003-022-03668-3
	7Y13	A	Orphan	Orphan	MRGPRD	Homo sapiens	-	-	-	3.1	2022-07-20	doi.org/10.1038/s42003-022-03668-3
	7Y14	A	Orphan	Orphan	MRGPRD	Homo sapiens	β-Alanine	-	-	3.2	2022-07-20	doi.org/10.1038/s42003-022-03668-3
	7Y15	A	Orphan	Orphan	MRGPRD	Homo sapiens	-	-	Gi1/β1/γ2	2.9	2022-07-20	doi.org/10.1038/s42003-022-03668-3
	7Y15 (No Gprot)	A	Orphan	Orphan	MRGPRD	Homo sapiens	-	-		2.9	2022-07-20	doi.org/10.1038/s42003-022-03668-3
	9DQH	A	Orphan	Orphan	MRGPRD	Homo sapiens	EP-2825	-	chim(NtGi1-Gs-CtGq)/β1/γ2	2.92	2024-12-11	doi.org/10.1016/j.celrep.2024.114942
	9DQH (No Gprot)	A	Orphan	Orphan	MRGPRD	Homo sapiens	EP-2825	-		2.92	2024-12-11	doi.org/10.1016/j.celrep.2024.114942
	9DQJ	A	Orphan	Orphan	MRGPRD	Homo sapiens	EP-3945	-	chim(NtGi1-Gs-CtGq)/β1/γ2	2.9	2024-12-11	doi.org/10.1016/j.celrep.2024.114942
	9DQJ (No Gprot)	A	Orphan	Orphan	MRGPRD	Homo sapiens	EP-3945	-		2.9	2024-12-11	doi.org/10.1016/j.celrep.2024.114942

there is no ligand in network 7Y15_nogp

Data downloads are temporarily suspended for technical reasons. We apologize for the inconvenience.

Data downloads are temporarily suspended for technical reasons.
We apologize for the inconvenience.