psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:Y106	18.71	Yes	Yes	1	0	3
2	L:L:?1	R:R:Y109	3.74	Yes	Yes	1	0	8
3	L:L:?1	R:R:T160	3.53	Yes	No	1	0	4
4	L:L:?1	R:R:C164	3.8	Yes	No	0	0	6
5	L:L:?1	R:R:F170	3.89	Yes	No	0	0	1
6	L:L:?1	R:R:D179	18.41	Yes	No	1	0	3
7	L:L:?1	R:R:Q182	9.56	Yes	Yes	1	0	6
8	L:L:?1	R:R:A183	5.03	Yes	No	0	0	5
9	L:L:?1	R:R:S238	4.79	Yes	No	1	0	7
10	L:L:?1	R:R:W241	33.62	Yes	Yes	1	0	4
11	L:L:?1	R:R:F242	3.89	Yes	No	0	0	5
12	L:L:?1	R:R:Y245	11.22	Yes	Yes	1	0	4
13	R:R:L256	R:R:V23	5.96	No	No	0	2	1
14	R:R:V255	R:R:Y27	11.36	No	No	0	1	3
15	R:R:L28	R:R:S31	6.01	No	No	0	4	3
16	R:R:L28	R:R:S32	4.5	No	No	0	4	5
17	R:R:L30	R:R:S259	7.51	No	No	0	5	3
18	R:R:L263	R:R:L33	4.15	No	No	0	5	5
19	R:R:F36	R:R:M35	3.73	No	Yes	0	5	4
20	R:R:S266	R:R:T37	6.4	No	No	0	6	7
21	R:R:S270	R:R:T37	3.2	No	No	0	8	7
22	R:R:C38	R:R:L76	3.17	Yes	No	0	6	7
23	R:R:C38	R:R:M79	3.24	Yes	No	0	6	5
24	R:R:A80	R:R:C38	3.61	No	Yes	0	6	6
25	R:R:M42	R:R:S46	4.6	No	No	0	7	6
26	R:R:D72	R:R:N45	6.73	Yes	No	0	9	9
27	R:R:L73	R:R:N45	9.61	No	No	0	7	9
28	R:R:N45	R:R:P273	4.89	No	No	0	9	9
29	R:R:L73	R:R:S46	7.51	No	No	0	7	6
30	R:R:L51	R:R:M47	11.31	No	No	0	7	6
31	R:R:A69	R:R:V48	3.39	No	No	0	9	9
32	R:R:F277	R:R:V48	5.24	No	No	0	7	9
33	R:R:A69	R:R:I49	3.25	No	No	0	9	7
34	R:R:F277	R:R:L51	3.65	No	No	0	7	7
35	R:R:L52	R:R:L66	9.69	No	No	0	8	8
36	R:R:C62	R:R:P60	3.77	No	No	0	8	7
37	R:R:F61	R:R:I65	12.56	Yes	No	0	8	8
38	R:R:F61	R:R:I119	8.79	Yes	Yes	3	8	9
39	R:R:F61	R:R:Q122	3.51	Yes	Yes	3	8	9
40	R:R:F61	R:R:R123	5.34	Yes	No	3	8	9
41	R:R:I63	R:R:N67	4.25	No	No	0	7	9
42	R:R:I63	R:R:S142	9.29	No	No	0	7	9
43	R:R:A118	R:R:Y64	5.34	No	Yes	0	8	8
44	R:R:I119	R:R:Y64	4.84	Yes	Yes	0	9	8
45	R:R:Q122	R:R:Y64	9.02	Yes	Yes	0	9	8
46	R:R:S142	R:R:Y64	13.99	No	Yes	0	9	8
47	R:R:V145	R:R:Y64	3.79	No	Yes	0	6	8
48	R:R:C146	R:R:Y64	4.03	No	Yes	0	7	8
49	R:R:I65	R:R:Y276	3.63	No	Yes	0	8	9
50	R:R:C146	R:R:N67	11.02	No	No	0	7	9
51	R:R:N67	R:R:W150	5.65	No	No	0	9	9
52	R:R:D72	R:R:L68	9.5	Yes	No	4	9	9
53	R:R:L68	R:R:N272	6.87	No	No	4	9	9
54	R:R:A71	R:R:V111	3.39	No	Yes	0	9	7
55	R:R:D72	R:R:S269	5.89	Yes	No	0	9	9
56	R:R:D72	R:R:N272	6.73	Yes	No	4	9	9
57	R:R:L104	R:R:L74	4.15	No	No	0	5	6
58	R:R:A108	R:R:L74	4.73	No	No	0	7	6
59	R:R:F75	R:R:M105	3.73	No	Yes	0	6	4
60	R:R:A108	R:R:F75	4.16	No	No	0	7	6
61	R:R:F75	R:R:Y109	5.16	No	Yes	0	6	8
62	R:R:L76	R:R:S269	10.51	No	No	0	7	9
63	R:R:F77	R:R:S81	7.93	No	No	0	4	5
64	R:R:M105	R:R:M79	5.78	Yes	No	0	4	5
65	R:R:M79	R:R:R262	4.96	No	Yes	0	5	4
66	R:R:M101	R:R:S81	4.6	No	No	0	4	5
67	R:R:E86	R:R:T82	5.64	Yes	No	0	3	3
68	R:R:E86	R:R:L83	6.63	Yes	No	5	3	6
69	R:R:L83	R:R:R262	17.01	No	Yes	5	6	4
70	R:R:L85	R:R:T94	4.42	No	No	0	3	1
71	R:R:H98	R:R:L85	6.43	No	No	0	5	3
72	R:R:E86	R:R:H98	4.92	Yes	No	0	3	5
73	R:R:E86	R:R:R262	5.82	Yes	Yes	5	3	4
74	R:R:Q88	R:R:T94	9.92	No	No	0	4	1
75	R:R:D95	R:R:L90	8.14	No	No	0	1	1
76	R:R:T94	R:R:V91	9.52	No	No	0	1	4
77	R:R:D95	R:R:F167	3.58	No	No	0	1	1
78	R:R:E99	R:R:R103	8.14	No	Yes	6	5	4
79	R:R:E99	R:R:S165	10.06	No	No	6	5	3
80	R:R:E99	R:R:F167	3.5	No	No	0	5	1
81	R:R:K102	R:R:R103	8.66	No	Yes	0	3	4
82	R:R:K102	R:R:Y106	8.36	No	Yes	0	3	3
83	R:R:R103	R:R:S161	5.27	Yes	No	0	4	3
84	R:R:R103	R:R:S165	6.59	Yes	No	6	4	3
85	R:R:M105	R:R:Y106	8.38	Yes	Yes	0	4	3
86	R:R:W241	R:R:Y106	7.72	Yes	Yes	1	4	3
87	R:R:F107	R:R:V111	5.24	Yes	Yes	1	5	7
88	R:R:F107	R:R:W150	6.01	Yes	No	1	5	9
89	R:R:F107	R:R:N157	9.67	Yes	No	1	5	7
90	R:R:L113	R:R:Y109	7.03	No	Yes	0	8	8
91	R:R:L237	R:R:Y109	11.72	No	Yes	0	5	8
92	R:R:S238	R:R:Y109	5.09	No	Yes	1	7	8
93	R:R:C153	R:R:T110	5.07	No	No	0	8	6
94	R:R:N157	R:R:T110	10.24	No	No	1	7	6
95	R:R:Q182	R:R:T110	5.67	Yes	No	1	6	6
96	R:R:V111	R:R:W150	17.16	Yes	No	1	7	9
97	R:R:C153	R:R:V111	5.12	No	Yes	0	8	7
98	R:R:F230	R:R:L113	4.87	Yes	No	0	9	8
99	R:R:L149	R:R:S114	6.01	No	No	0	7	7
100	R:R:C153	R:R:S114	3.44	No	No	0	8	7
101	R:R:L190	R:R:S114	4.5	Yes	No	0	8	7
102	R:R:F230	R:R:L116	4.87	Yes	No	0	9	9
103	R:R:L116	R:R:Y276	5.86	No	Yes	0	9	9
104	R:R:L190	R:R:T117	7.37	Yes	No	0	8	8
105	R:R:T117	R:R:V193	3.17	No	No	0	8	6
106	R:R:I119	R:R:R123	3.76	Yes	No	3	9	9
107	R:R:I119	R:R:Y276	6.04	Yes	Yes	0	9	9
108	R:R:M194	R:R:S120	6.13	No	No	0	8	9
109	R:R:S120	R:R:S197	4.89	No	No	0	9	8
110	R:R:S120	R:R:S198	4.89	No	No	0	9	8
111	R:R:S197	R:R:T121	3.2	No	No	0	8	6
112	R:R:F133	R:R:Q122	4.68	No	Yes	3	7	9
113	R:R:Q122	R:R:R137	3.5	Yes	Yes	3	9	9
114	R:R:C124	R:R:L128	4.76	No	Yes	7	8	6
115	R:R:C124	R:R:S197	5.16	No	No	0	8	8
116	R:R:C124	R:R:T200	3.38	No	No	7	8	5
117	R:R:L125	R:R:W132	3.42	No	No	0	6	6
118	R:R:F133	R:R:S126	7.93	No	No	0	7	8
119	R:R:L201	R:R:V127	4.47	No	No	0	8	8
120	R:R:V127	R:R:V205	4.81	No	No	0	8	6
121	R:R:F129	R:R:L128	3.65	No	Yes	0	5	6
122	R:R:L128	R:R:T200	4.42	Yes	No	7	6	5
123	R:R:L128	R:R:W204	12.53	Yes	No	0	6	6
124	R:R:R137	R:R:W132	10	Yes	No	0	9	6
125	R:R:F133	R:R:R137	9.62	No	Yes	3	7	9
126	R:R:C135	R:R:K134	3.23	No	No	0	7	7
127	R:R:C135	R:R:H136	7.37	No	No	0	7	6
128	R:R:L141	R:R:R137	6.07	No	Yes	0	5	9
129	R:R:L141	R:R:P138	3.28	No	No	0	5	8
130	R:R:H140	R:R:R139	9.03	No	No	0	5	5
131	R:R:H140	R:R:W144	4.23	No	No	0	5	5
132	R:R:M156	R:R:Q182	12.23	No	Yes	0	4	6
133	R:R:N157	R:R:Q182	7.92	No	Yes	1	7	6
134	R:R:G158	R:R:S161	3.71	No	No	0	4	3
135	R:R:F163	R:R:L159	7.31	No	No	0	4	6
136	R:R:T160	R:R:V178	11.11	No	No	0	4	4
137	R:R:Q182	R:R:T160	5.67	Yes	No	1	6	4
138	R:R:K169	R:R:S162	4.59	No	No	0	1	3
139	R:R:F163	R:R:R174	9.62	No	No	0	4	1
140	R:R:C164	R:R:C175	7.28	No	No	0	6	8
141	R:R:N171	R:R:R174	7.23	No	No	0	5	1
142	R:R:D173	R:R:E172	3.9	No	No	0	3	3
143	R:R:D173	R:R:R174	4.76	No	No	0	3	1
144	R:R:D173	R:R:R177	19.06	No	No	0	3	3
145	R:R:F176	R:R:M180	11.2	No	No	0	2	3
146	R:R:D179	R:R:Y245	11.49	No	Yes	1	3	4
147	R:R:G188	R:R:P192	4.06	No	No	0	5	5
148	R:R:P192	R:R:T191	3.5	No	No	0	5	5
149	R:R:F230	R:R:T191	6.49	Yes	No	0	9	5
150	R:R:L235	R:R:T191	7.37	No	No	0	6	5
151	R:R:F230	R:R:M194	12.44	Yes	No	0	9	8
152	R:R:L231	R:R:T195	4.42	No	No	0	8	4
153	R:R:S198	R:R:V223	3.23	No	No	0	8	8
154	R:R:S198	R:R:V227	3.23	No	No	0	8	8
155	R:R:L201	R:R:L219	4.15	No	No	0	8	7
156	R:R:F202	R:R:R206	11.76	No	No	2	5	5
157	R:R:F202	R:R:F220	15	No	Yes	2	5	5
158	R:R:F202	R:R:L224	3.65	No	No	0	5	5
159	R:R:L219	R:R:V205	7.45	No	No	0	7	6
160	R:R:F220	R:R:R206	5.34	Yes	No	2	5	5
161	R:R:S209	R:R:W212	4.94	No	Yes	2	7	3
162	R:R:Q215	R:R:S209	8.66	No	No	2	5	7
163	R:R:P216	R:R:S209	5.34	Yes	No	2	7	7
164	R:R:Q211	R:R:W212	4.38	No	Yes	0	5	3
165	R:R:P216	R:R:W212	10.81	Yes	Yes	2	7	3
166	R:R:P216	R:R:Q215	4.74	Yes	No	2	7	5
167	R:R:F220	R:R:P216	4.33	Yes	Yes	2	5	7
168	R:R:S226	R:R:Y276	8.9	No	Yes	0	7	9
169	R:R:S268	R:R:V229	3.23	Yes	No	0	9	7
170	R:R:C233	R:R:S264	3.44	No	No	0	7	7
171	R:R:C233	R:R:V267	3.42	No	No	0	7	5
172	R:R:C233	R:R:S268	3.44	No	Yes	0	7	9
173	R:R:S234	R:R:S268	6.52	No	Yes	0	7	9
174	R:R:P236	R:R:S261	3.56	No	No	0	9	5
175	R:R:W241	R:R:Y240	9.65	Yes	Yes	1	4	3
176	R:R:L244	R:R:Y240	9.38	No	Yes	1	3	3
177	R:R:Q254	R:R:Y240	7.89	No	Yes	1	2	3
178	R:R:F258	R:R:Y240	8.25	No	Yes	0	3	3
179	R:R:L244	R:R:W241	4.56	No	Yes	1	3	4
180	R:R:L247	R:R:V243	4.47	No	No	0	3	5
181	R:R:L244	R:R:Q254	6.65	No	No	1	3	2
182	R:R:W246	R:R:Y245	3.86	No	Yes	0	4	4
183	R:R:L249	R:R:P250	4.93	No	No	0	3	1
184	R:R:L249	R:R:M253	4.24	No	No	0	3	1
185	R:R:E252	R:R:P251	6.29	No	No	0	2	2
186	R:R:F258	R:R:R262	4.28	No	Yes	0	3	4
187	R:R:R262	R:R:S259	3.95	Yes	No	0	4	3
188	R:R:N272	R:R:S268	4.47	No	Yes	0	9	9
189	R:R:A271	R:R:I275	3.25	No	No	0	7	8
190	R:R:I275	R:R:Y276	4.84	No	Yes	0	8	9
191	R:R:P89	R:R:Q88	3.16	No	No	0	3	4
192	R:R:I186	R:R:S238	3.1	No	No	0	7	7
193	R:R:R262	R:R:Y27	3.09	Yes	No	0	4	3
194	R:R:M101	R:R:V97	3.04	No	No	0	4	5
195	R:R:M101	R:R:T82	3.01	No	No	0	4	3
196	R:R:L168	R:R:S165	3	No	No	0	1	3
197	R:R:L237	R:R:S265	3	No	No	0	5	8
198	R:R:L33	R:R:V29	2.98	No	No	0	5	4
199	R:R:L128	R:R:V127	2.98	Yes	No	0	6	8
200	R:R:L159	R:R:V178	2.98	No	No	0	6	4
201	R:R:L190	R:R:V189	2.98	Yes	No	0	8	5
202	R:R:L224	R:R:V223	2.98	No	No	0	5	8
203	R:R:L231	R:R:V227	2.98	No	No	0	8	8
204	R:R:I186	R:R:M187	2.92	No	No	0	7	7
205	R:R:I49	R:R:L73	2.85	No	No	0	7	7
206	R:R:I232	R:R:L228	2.85	No	No	0	5	6
207	R:R:L39	R:R:M35	2.83	No	Yes	0	6	4
208	R:R:L260	R:R:L30	2.77	No	No	0	4	5
209	R:R:A34	R:R:R262	2.77	No	Yes	0	6	4
210	R:R:L100	R:R:L104	2.77	No	No	0	4	5
211	R:R:L115	R:R:L149	2.77	No	No	0	7	7
212	R:R:L185	R:R:L190	2.77	No	Yes	0	5	8
213	R:R:F220	R:R:T217	2.59	Yes	No	0	5	5
214	R:R:F107	R:R:L154	2.44	Yes	No	0	5	4
215	R:R:M180	R:R:Y245	2.39	No	Yes	0	3	4
216	R:R:Q210	R:R:R207	2.34	No	No	0	5	5
217	R:R:H136	R:R:W132	2.12	No	No	0	6	6
218	R:R:R214	R:R:W212	2	No	Yes	0	4	3
219	R:R:C40	R:R:G41	1.96	No	No	0	6	9
220	R:R:C146	R:R:G147	1.96	No	No	0	7	5
221	R:R:A43	R:R:G44	1.95	No	No	0	5	9
222	R:R:P250	R:R:P251	1.95	No	No	0	1	2
223	R:R:G41	R:R:S270	1.86	No	No	0	9	8
224	R:R:G112	R:R:V111	1.84	No	Yes	0	9	7
225	R:R:P236	R:R:S264	1.78	No	No	0	9	7
226	R:R:G44	R:R:M47	1.75	No	No	0	9	6
227	R:R:C38	R:R:S266	1.72	Yes	No	0	6	6
228	R:R:A271	R:R:V274	1.7	No	No	0	7	6
229	R:R:C135	R:R:I131	1.64	No	No	0	7	7
230	R:R:A70	R:R:I49	1.62	No	No	0	5	7
231	R:R:S226	R:R:V222	1.62	No	No	0	7	7
232	R:R:A80	R:R:M35	1.61	No	Yes	0	6	4
233	R:R:V23	R:R:V255	1.6	No	No	0	1	1
234	R:R:V222	R:R:V279	1.6	No	No	8	7	7
235	R:R:T25	R:R:V29	1.59	No	No	0	2	4
236	R:R:C62	R:R:L52	1.59	No	No	0	8	8
237	R:R:C257	R:R:L249	1.59	No	No	0	4	3
238	R:R:A26	R:R:L256	1.58	No	No	0	3	2
239	R:R:P60	R:R:Q122	1.58	No	Yes	0	7	9
240	R:R:I239	R:R:V243	1.54	No	No	0	6	5
241	R:R:M35	R:R:S84	1.53	Yes	No	0	4	5
242	R:R:M105	R:R:S78	1.53	Yes	No	0	4	5
243	R:R:M156	R:R:V181	1.52	No	No	0	4	3
244	R:R:L83	R:R:S31	1.5	No	No	0	6	3
245	R:R:L33	R:R:S32	1.5	No	No	0	5	5
246	R:R:L263	R:R:S266	1.5	No	No	0	5	6
247	R:R:A143	R:R:H140	1.46	No	No	0	5	5
248	R:R:I239	R:R:M187	1.46	No	No	0	6	7
249	R:R:F129	R:R:P130	1.44	No	No	0	5	9
250	R:R:E252	R:R:V23	1.43	No	No	0	2	1
251	R:R:Q88	R:R:T87	1.42	No	No	0	4	4
252	R:R:K169	R:R:L168	1.41	No	No	0	1	1
253	R:R:P138	R:R:W144	1.35	No	No	0	8	5
254	R:R:R218	R:R:V222	1.31	No	No	8	7	7
255	R:R:R218	R:R:V279	1.31	No	No	8	7	7
256	R:R:Q210	R:R:Q211	1.28	No	No	0	5	5
257	R:R:V203	R:R:W204	1.23	No	No	0	5	6
258	R:R:F277	R:R:L278	1.22	No	No	0	7	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:?1	10.0158	12	1	0
2	R:R:M35	2.425	4	0	4
3	R:R:C38	2.935	4	0	6
4	R:R:F61	7.55	4	3	8
5	R:R:Y64	6.835	6	0	8
6	R:R:D72	7.2125	4	4	9
7	R:R:E86	5.7525	4	5	3
8	R:R:R103	7.165	4	6	4
9	R:R:M105	4.855	4	0	4
10	R:R:Y106	10.7925	4	1	3
11	R:R:F107	5.84	4	1	5
12	R:R:Y109	6.548	5	1	8
13	R:R:V111	6.55	5	1	7
14	R:R:I119	5.8575	4	3	9
15	R:R:Q122	4.458	5	3	9
16	R:R:L128	5.668	5	7	6
17	R:R:R137	7.2975	4	3	9
18	R:R:Q182	8.21	5	1	6
19	R:R:L190	4.405	4	0	8
20	R:R:W212	5.5325	4	2	3
21	R:R:P216	6.305	4	2	7
22	R:R:F220	6.815	4	2	5
23	R:R:F230	7.1675	4	0	9
24	R:R:Y240	8.7925	4	1	3
25	R:R:W241	13.8875	4	1	4
26	R:R:Y245	7.24	4	1	4
27	R:R:R262	5.98286	7	5	4
28	R:R:S268	4.415	4	0	9
29	R:R:Y276	5.854	5	0	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:Y106	43.0108	18.71	Yes	Yes	1	0	3
2	R:R:M105	R:R:Y106	34.9176	8.38	Yes	Yes	0	4	3
3	R:R:M105	R:R:M79	98.9884	5.78	Yes	No	0	4	5
4	R:R:M79	R:R:R262	50.5694	4.96	No	Yes	0	5	4
5	R:R:R262	R:R:Y27	22.4916	3.09	Yes	No	0	4	3
6	R:R:V255	R:R:Y27	20.7419	11.36	No	No	0	1	3
7	R:R:V23	R:R:V255	18.9285	1.6	No	No	0	1	1
8	L:L:?1	R:R:W241	17.9296	33.62	Yes	Yes	1	0	4
9	R:R:W241	R:R:Y240	15.0092	9.65	Yes	Yes	1	4	3
10	R:R:F258	R:R:Y240	13.8831	8.25	No	Yes	0	3	3
11	R:R:F258	R:R:R262	13.2532	4.28	No	Yes	0	3	4
12	R:R:C38	R:R:M79	66.5903	3.24	Yes	No	0	6	5
13	R:R:C38	R:R:S266	17.0516	1.72	Yes	No	0	6	6
14	R:R:C38	R:R:L76	45.7785	3.17	Yes	No	0	6	7
15	R:R:L76	R:R:S269	44.3151	10.51	No	No	0	7	9
16	R:R:D72	R:R:S269	42.839	5.89	Yes	No	0	9	9
17	R:R:D72	R:R:N45	25.7619	6.73	Yes	No	0	9	9
18	R:R:L73	R:R:N45	22.4916	9.61	No	No	0	7	9
19	R:R:I49	R:R:L73	17.4906	2.85	No	No	0	7	7
20	R:R:A69	R:R:I49	14.093	3.25	No	No	0	9	7
21	R:R:A69	R:R:V48	12.3751	3.39	No	No	0	9	9
22	R:R:F277	R:R:V48	10.6445	5.24	No	No	0	7	9
23	L:L:?1	R:R:Y109	33.0279	3.74	Yes	Yes	1	0	8
24	R:R:L113	R:R:Y109	100	7.03	No	Yes	0	8	8
25	R:R:F230	R:R:L113	99.771	4.87	Yes	No	0	9	8
26	R:R:F230	R:R:L116	81.9431	4.87	Yes	No	0	9	9
27	R:R:L116	R:R:Y276	81.2941	5.86	No	Yes	0	9	9
28	R:R:I65	R:R:Y276	23.9995	3.63	No	Yes	0	8	9
29	R:R:F61	R:R:I65	23.1024	12.56	Yes	No	0	8	8
30	R:R:F61	R:R:Q122	43.7615	3.51	Yes	Yes	3	8	9
31	R:R:P60	R:R:Q122	15.4355	1.58	No	Yes	0	7	9
32	R:R:C62	R:R:P60	11.618	3.77	No	No	0	8	7
33	R:R:I119	R:R:Y276	53.019	6.04	Yes	Yes	0	9	9
34	R:R:F61	R:R:I119	23.1278	8.79	Yes	Yes	3	8	9
35	R:R:I119	R:R:Y64	28.9623	4.84	Yes	Yes	0	9	8
36	R:R:Q122	R:R:Y64	30.362	9.02	Yes	Yes	0	9	8
37	L:L:?1	R:R:Q182	37.9971	9.56	Yes	Yes	1	0	6
38	R:R:N157	R:R:Q182	20.5955	7.92	No	Yes	1	7	6
39	R:R:F107	R:R:N157	19.8957	9.67	Yes	No	1	5	7
40	R:R:F107	R:R:W150	13.7622	6.01	Yes	No	1	5	9
41	R:R:N67	R:R:W150	16.4408	5.65	No	No	0	9	9
42	R:R:C146	R:R:N67	13.444	11.02	No	No	0	7	9
43	R:R:C146	R:R:Y64	12.1588	4.03	No	Yes	0	7	8
44	R:R:D72	R:R:N272	15.7409	6.73	Yes	No	4	9	9
45	R:R:Q182	R:R:T110	17.2934	5.67	Yes	No	1	6	6
46	R:R:C153	R:R:T110	16.3517	5.07	No	No	0	8	6
47	R:R:F75	R:R:Y109	69.4089	5.16	No	Yes	0	6	8
48	R:R:E86	R:R:R262	25.4311	5.82	Yes	Yes	5	3	4
49	R:R:E86	R:R:T82	10.2882	5.64	Yes	No	0	3	3
50	R:R:E86	R:R:H98	14.4111	4.92	Yes	No	0	3	5
51	R:R:H98	R:R:L85	12.6169	6.43	No	No	0	5	3
52	R:R:L85	R:R:T94	10.5427	4.42	No	No	0	3	1
53	R:R:K102	R:R:Y106	21.5245	8.36	No	Yes	0	3	3
54	R:R:K102	R:R:R103	19.9847	8.66	No	Yes	0	3	4
55	R:R:C153	R:R:S114	13.3295	3.44	No	No	0	8	7
56	R:R:F230	R:R:M194	51.7465	12.44	Yes	No	0	9	8
57	R:R:M194	R:R:S120	50.3977	6.13	No	No	0	8	9
58	R:R:S120	R:R:S197	22.8733	4.89	No	No	0	9	8
59	R:R:S120	R:R:S198	29.2868	4.89	No	No	0	9	8
60	R:R:C124	R:R:S197	19.6539	5.16	No	No	0	8	8
61	R:R:C124	R:R:L128	16.3199	4.76	No	Yes	7	8	6
62	R:R:Q122	R:R:R137	48.3807	3.5	Yes	Yes	3	9	9
63	R:R:R137	R:R:W132	23.1278	10	Yes	No	0	9	6
64	R:R:H136	R:R:W132	15.4673	2.12	No	No	0	6	6
65	R:R:C135	R:R:H136	11.618	7.37	No	No	0	7	6
66	R:R:L141	R:R:R137	22.657	6.07	No	Yes	0	5	9
67	R:R:L141	R:R:P138	19.3039	3.28	No	No	0	5	8
68	R:R:P138	R:R:W144	15.4673	1.35	No	No	0	8	5
69	R:R:H140	R:R:W144	11.618	4.23	No	No	0	5	5
70	L:L:?1	R:R:T160	11.8534	3.53	Yes	No	1	0	4
71	R:R:T160	R:R:V178	13.3804	11.11	No	No	0	4	4
72	R:R:L159	R:R:V178	11.7516	2.98	No	No	0	6	4
73	R:R:F163	R:R:L159	10.1101	7.31	No	No	0	4	6
74	R:R:S198	R:R:V223	22.9878	3.23	No	No	0	8	8
75	R:R:L224	R:R:V223	21.6326	2.98	No	No	0	5	8
76	R:R:F202	R:R:L224	19.9975	3.65	No	No	0	5	5
77	R:R:F202	R:R:F220	16.6571	15	No	Yes	2	5	5
78	R:R:F220	R:R:P216	13.3931	4.33	Yes	Yes	2	5	7
79	R:R:N272	R:R:S268	14.093	4.47	No	Yes	0	9	9
80	R:R:I186	R:R:S238	12.3051	3.1	No	No	0	7	7
81	R:R:E252	R:R:V23	12.7314	1.43	No	No	0	2	1
82	R:R:E252	R:R:P251	10.6509	6.29	No	No	0	2	2
83	R:R:F75	R:R:M105	66.8003	3.73	No	Yes	0	6	4

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?1	R:R:Y106	18.71	1	Yes	Yes	0	3	0	1
L:L:?1	R:R:Y109	3.74	1	Yes	Yes	0	8	0	1
L:L:?1	R:R:T160	3.53	1	Yes	No	0	4	0	1
L:L:?1	R:R:C164	3.8	1	Yes	No	0	6	0	1
L:L:?1	R:R:F170	3.89	1	Yes	No	0	1	0	1
L:L:?1	R:R:D179	18.41	1	Yes	No	0	3	0	1
L:L:?1	R:R:Q182	9.56	1	Yes	Yes	0	6	0	1
L:L:?1	R:R:A183	5.03	1	Yes	No	0	5	0	1
L:L:?1	R:R:S238	4.79	1	Yes	No	0	7	0	1
L:L:?1	R:R:W241	33.62	1	Yes	Yes	0	4	0	1
L:L:?1	R:R:F242	3.89	1	Yes	No	0	5	0	1
L:L:?1	R:R:Y245	11.22	1	Yes	Yes	0	4	0	1
R:R:F75	R:R:M105	3.73	0	No	Yes	6	4	2	2
R:R:F75	R:R:Y109	5.16	0	No	Yes	6	8	2	1
R:R:K102	R:R:Y106	8.36	0	No	Yes	3	3	2	1
R:R:M105	R:R:Y106	8.38	0	Yes	Yes	4	3	2	1
R:R:W241	R:R:Y106	7.72	1	Yes	Yes	4	3	1	1
R:R:L113	R:R:Y109	7.03	0	No	Yes	8	8	2	1
R:R:L237	R:R:Y109	11.72	0	No	Yes	5	8	2	1
R:R:S238	R:R:Y109	5.09	1	No	Yes	7	8	1	1
R:R:N157	R:R:T110	10.24	1	No	No	7	6	2	2
R:R:Q182	R:R:T110	5.67	1	Yes	No	6	6	1	2
R:R:M156	R:R:Q182	12.23	0	No	Yes	4	6	2	1
R:R:N157	R:R:Q182	7.92	1	No	Yes	7	6	2	1
R:R:T160	R:R:V178	11.11	1	No	No	4	4	1	2
R:R:Q182	R:R:T160	5.67	1	Yes	No	6	4	1	1
R:R:C164	R:R:C175	7.28	0	No	No	6	8	1	2
R:R:D179	R:R:Y245	11.49	1	No	Yes	3	4	1	1
R:R:W241	R:R:Y240	9.65	1	Yes	Yes	4	3	1	2
R:R:L244	R:R:Y240	9.38	1	No	Yes	3	3	2	2
R:R:L244	R:R:W241	4.56	1	No	Yes	3	4	2	1
R:R:W246	R:R:Y245	3.86	0	No	Yes	4	4	2	1
R:R:I186	R:R:S238	3.1	0	No	No	7	7	2	1
R:R:M180	R:R:Y245	2.39	0	No	Yes	3	4	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	9DQJ_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.17
Number of Linked Nodes	233
Number of Links	258
Number of Hubs	29
Number of Links mediated by Hubs	117
Number of Communities	8
Number of Nodes involved in Communities	45
Number of Links involved in Communities	55

Path Summary
Number Of Nodes in MetaPath	84
Number Of Links MetaPath	83
Number of Shortest Paths	37112
Length Of Smallest Path	3
Average Path Length	13.3169
Length of Longest Path	32
Minimum Path Strength	1.465
Average Path Strength	6.13445
Maximum Path Strength	26.015
Minimum Path Correlation	0.7
Average Path Correlation	0.923278
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	5.26316
Average % Of Corr. Nodes	47.1329
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	39.8164
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	A1B
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	A1B
Name	1-deoxy-alpha-L-xylulofuranose-1,2-borate
Synonyms
Identifier
Formula	C5 H10 B O6
Molecular Weight	176.94
SMILES
PubChem	118797262
Formal Charge	-1
Total Atoms	22
Total Chiral Atoms	3
Total Bonds	23
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q8TDS7
Sequence	>9DQJ_nogp_Chain_R S T V H T A Y L V L S S L A M F T C L C G M A G N S M V I W L L P F C I Y I L N L A A A D L L F L F S M A S T L S L E T Q P L V N T T D K V H E L M K R L M Y F A Y T V G L S L L T A I S T Q R C L S V L F P I W F K C H R P R H L S A W V C G L L W T L C L L M N G L T S S F C S K F L K F N E D R C F R V D M V Q A A L I M G V L T P V M T L S S L T L F V W V R R S S Q Q W R R Q P T R L F V V V L A S V L V F L I C S L P L S I Y W F V L Y W L S L P P E M Q V L C F S L S R L S S S V S S S A N P V I Y F L V Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	9DQH	A	Orphan	Orphan	MRGPRD	Homo sapiens	EP-2825	-	chim(NtGi1-Gs-CtGq)/β1/γ2	2.92	2024-12-11	doi.org/10.1016/j.celrep.2024.114942
	9DQH (No Gprot)	A	Orphan	Orphan	MRGPRD	Homo sapiens	EP-2825	-		2.92	2024-12-11	doi.org/10.1016/j.celrep.2024.114942
	9DQJ	A	Orphan	Orphan	MRGPRD	Homo sapiens	EP-3945	-	chim(NtGi1-Gs-CtGq)/β1/γ2	2.9	2024-12-11	doi.org/10.1016/j.celrep.2024.114942
	9DQJ (No Gprot)	A	Orphan	Orphan	MRGPRD	Homo sapiens	EP-3945	-		2.9	2024-12-11	doi.org/10.1016/j.celrep.2024.114942
	7Y12	A	Orphan	Orphan	MRGPRD	Homo sapiens	β-Alanine	-	Gi1/β1/γ2	3.1	2022-07-20	doi.org/10.1038/s42003-022-03668-3
	7Y12 (No Gprot)	A	Orphan	Orphan	MRGPRD	Homo sapiens	β-Alanine	-		3.1	2022-07-20	doi.org/10.1038/s42003-022-03668-3
	7Y13	A	Orphan	Orphan	MRGPRD	Homo sapiens	-	-	-	3.1	2022-07-20	doi.org/10.1038/s42003-022-03668-3
	7Y14	A	Orphan	Orphan	MRGPRD	Homo sapiens	β-Alanine	-	-	3.2	2022-07-20	doi.org/10.1038/s42003-022-03668-3
	7Y15	A	Orphan	Orphan	MRGPRD	Homo sapiens	-	-	Gi1/β1/γ2	2.9	2022-07-20	doi.org/10.1038/s42003-022-03668-3
	7Y15 (No Gprot)	A	Orphan	Orphan	MRGPRD	Homo sapiens	-	-		2.9	2022-07-20	doi.org/10.1038/s42003-022-03668-3

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 9DQJ_nogp.zip

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