psnGPCR

Press and hold down the left mouse button and move the mouse to rotate.
Press and hold down the central mouse button and move the mouse to translate.
Use the mouse wheel to zoom in or out.
Click on any atom on your molecule and the corresponding residue label will be placed beneath the viewer.

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:T132	4.43	Yes	No	1	0	5
2	L:L:?1	R:R:Y135	29.06	Yes	Yes	1	0	5
3	L:L:?1	R:R:L181	4.16	Yes	No	0	0	4
4	L:L:?1	R:R:M189	4.25	Yes	No	0	0	4
5	L:L:?1	R:R:F205	3.66	Yes	Yes	0	0	4
6	L:L:?1	R:R:R208	9.13	Yes	No	0	0	5
7	L:L:?1	R:R:N220	11.35	Yes	No	1	0	4
8	L:L:?1	R:R:L223	8.32	Yes	No	0	0	5
9	L:L:?1	R:R:R286	13.69	Yes	Yes	1	0	6
10	L:L:?1	R:R:Y289	11.45	Yes	Yes	1	0	4
11	R:R:E50	R:R:L53	5.3	No	No	0	4	5
12	R:R:E303	R:R:E50	3.81	Yes	No	2	1	4
13	R:R:E50	R:R:K307	21.6	No	No	2	4	3
14	R:R:K51	R:R:S54	6.12	No	No	0	4	5
15	R:R:K51	R:R:T55	3	No	No	0	4	5
16	R:R:L53	R:R:L57	5.54	No	No	0	5	5
17	R:R:I311	R:R:L53	4.28	No	No	0	5	5
18	R:R:H114	R:R:L57	7.71	Yes	No	0	5	5
19	R:R:E310	R:R:L57	3.98	No	No	0	5	5
20	R:R:T58	R:R:T59	3.14	No	No	0	5	5
21	R:R:H114	R:R:T58	4.11	Yes	No	0	5	5
22	R:R:S60	R:R:V314	4.85	No	No	0	5	5
23	R:R:L107	R:R:Y61	11.72	No	No	0	7	8
24	R:R:F134	R:R:Y61	6.19	No	No	0	7	8
25	R:R:S317	R:R:Y61	6.36	No	No	0	7	8
26	R:R:I66	R:R:V63	3.07	No	No	0	5	5
27	R:R:F65	R:R:I66	3.77	Yes	No	0	7	5
28	R:R:F65	R:R:L69	3.65	Yes	No	0	7	6
29	R:R:F65	R:R:I104	3.77	Yes	No	0	7	5
30	R:R:F65	R:R:L107	3.65	Yes	No	0	7	7
31	R:R:F65	R:R:P108	7.22	Yes	No	0	7	9
32	R:R:C321	R:R:V67	3.42	No	No	0	7	6
33	R:R:I73	R:R:L69	4.28	No	No	0	3	6
34	R:R:G71	R:R:V70	3.68	No	No	0	8	4
35	R:R:I74	R:R:V70	3.07	No	No	0	5	4
36	R:R:D100	R:R:N72	14.81	No	No	0	9	9
37	R:R:L101	R:R:N72	4.12	No	No	0	7	9
38	R:R:N72	R:R:P324	6.52	No	No	0	9	9
39	R:R:I73	R:R:L101	2.85	No	No	0	3	7
40	R:R:G81	R:R:Y77	2.9	No	No	0	4	4
41	R:R:I82	R:R:V78	3.07	No	No	0	5	7
42	R:R:F79	R:R:L93	4.87	No	No	0	6	8
43	R:R:L80	R:R:R86	6.07	No	No	0	3	7
44	R:R:L80	R:R:L94	4.15	No	No	0	3	6
45	R:R:H83	R:R:Q90	7.42	No	No	0	5	7
46	R:R:Q90	R:R:R86	3.5	No	No	0	7	7
47	R:R:N87	R:R:Q90	17.17	No	No	0	8	7
48	R:R:D151	R:R:S88	5.89	No	No	0	8	6
49	R:R:S171	R:R:S88	4.89	No	No	0	7	6
50	R:R:I89	R:R:L93	2.85	Yes	No	0	7	8
51	R:R:I89	R:R:R152	3.76	Yes	No	0	7	9
52	R:R:I89	R:R:K155	2.91	Yes	No	0	7	8
53	R:R:I172	R:R:I91	2.94	No	No	0	4	6
54	R:R:I148	R:R:Y92	4.84	No	Yes	0	9	7
55	R:R:S171	R:R:Y92	7.63	No	Yes	0	7	7
56	R:R:V174	R:R:Y92	3.79	No	Yes	0	5	7
57	R:R:I148	R:R:L93	2.85	No	No	0	9	8
58	R:R:C175	R:R:N95	7.87	No	No	0	6	9
59	R:R:D100	R:R:V96	2.92	No	No	0	9	9
60	R:R:L144	R:R:V96	4.47	No	No	0	7	9
61	R:R:A99	R:R:I140	3.25	No	Yes	0	8	7
62	R:R:D100	R:R:S320	8.83	No	No	0	9	8
63	R:R:F105	R:R:L101	8.53	No	No	0	5	7
64	R:R:L102	R:R:N137	9.61	No	No	0	7	8
65	R:R:F134	R:R:L103	4.87	No	No	0	7	7
66	R:R:L103	R:R:N137	8.24	No	No	0	7	8
67	R:R:C106	R:R:L133	4.76	No	No	0	6	5
68	R:R:F109	R:R:M112	3.73	No	No	0	6	4
69	R:R:F109	R:R:V130	5.24	No	No	0	6	5
70	R:R:H114	R:R:R110	11.28	Yes	No	0	5	7
71	R:R:F205	R:R:R110	12.83	Yes	No	0	4	7
72	R:R:I111	R:R:I115	2.94	No	No	0	7	4
73	R:R:K119	R:R:M112	11.52	No	No	3	4	4
74	R:R:M112	R:R:T121	3.01	No	No	3	4	3
75	R:R:H114	R:R:Y113	6.53	Yes	No	0	5	5
76	R:R:N118	R:R:Y113	12.79	No	No	0	4	5
77	R:R:K119	R:R:N116	25.18	No	No	0	4	3
78	R:R:N118	R:R:Q117	3.96	No	No	0	4	3
79	R:R:K119	R:R:T121	16.52	No	No	3	4	3
80	R:R:V124	R:R:W120	6.13	No	No	0	4	9
81	R:R:N200	R:R:W120	15.82	No	No	0	5	9
82	R:R:T202	R:R:W120	7.28	No	No	0	4	9
83	R:R:L122	R:R:L126	8.3	No	No	0	7	5
84	R:R:I125	R:R:V124	3.07	No	No	0	1	4
85	R:R:I125	R:R:L194	5.71	No	No	0	1	4
86	R:R:C127	R:R:C204	7.28	No	No	0	9	9
87	R:R:K128	R:R:T193	6.01	No	No	0	8	5
88	R:R:T132	R:R:V129	6.35	No	No	1	5	5
89	R:R:F186	R:R:V129	5.24	Yes	No	1	7	5
90	R:R:I190	R:R:V129	12.29	No	No	1	5	5
91	R:R:F205	R:R:V130	3.93	Yes	No	0	4	5
92	R:R:F186	R:R:T132	6.49	Yes	No	1	7	5
93	R:R:L133	R:R:N137	8.24	No	No	0	5	8
94	R:R:F186	R:R:L133	3.65	Yes	No	0	7	5
95	R:R:Y135	R:R:Y139	2.98	Yes	No	0	5	7
96	R:R:Y135	R:R:Y282	5.96	Yes	Yes	1	5	6
97	R:R:R286	R:R:Y135	4.12	Yes	Yes	1	6	5
98	R:R:A182	R:R:M136	3.22	No	No	0	7	5
99	R:R:F186	R:R:M136	3.73	Yes	No	0	7	5
100	R:R:L223	R:R:Y139	5.86	No	No	0	5	7
101	R:R:H283	R:R:Y139	9.8	Yes	No	0	8	7
102	R:R:I140	R:R:L144	2.85	Yes	No	0	7	7
103	R:R:I140	R:R:V178	4.61	Yes	No	0	7	7
104	R:R:I140	R:R:W179	7.05	Yes	No	0	7	9
105	R:R:I142	R:R:I230	2.94	No	No	0	8	9
106	R:R:F279	R:R:I142	10.05	Yes	No	0	8	8
107	R:R:F147	R:R:I143	5.02	No	No	0	5	5
108	R:R:G146	R:R:I234	3.53	No	Yes	0	7	8
109	R:R:I148	R:R:R152	5.01	No	No	0	9	9
110	R:R:I234	R:R:S149	6.19	Yes	No	0	8	9
111	R:R:S149	R:R:Y238	5.09	No	Yes	0	9	8
112	R:R:I154	R:R:L150	2.85	No	No	0	6	5
113	R:R:D151	R:R:K155	6.91	No	No	0	8	8
114	R:R:R152	R:R:Y238	10.29	No	Yes	0	9	8
115	R:R:N157	R:R:Y153	15.12	No	Yes	0	7	7
116	R:R:R163	R:R:Y153	3.09	No	Yes	0	5	7
117	R:R:S237	R:R:Y153	6.36	No	Yes	0	6	7
118	R:R:K240	R:R:Y153	10.75	No	Yes	0	4	7
119	R:R:I241	R:R:Y153	4.84	No	Yes	0	8	7
120	R:R:I154	R:R:K164	2.91	No	No	0	6	3
121	R:R:Q162	R:R:R158	8.18	No	No	0	5	5
122	R:R:K164	R:R:R163	4.95	No	No	0	3	5
123	R:R:K169	R:R:Y173	4.78	No	No	0	4	2
124	R:R:F186	R:R:L183	4.87	Yes	No	0	7	4
125	R:R:L183	R:R:L187	5.54	No	No	0	4	4
126	R:R:G185	R:R:T188	3.64	No	No	0	4	8
127	R:R:F219	R:R:G185	3.01	Yes	No	0	5	4
128	R:R:F186	R:R:I190	3.77	Yes	No	1	7	5
129	R:R:E216	R:R:M189	4.06	Yes	No	0	3	4
130	R:R:F219	R:R:M189	4.98	Yes	No	0	5	4
131	R:R:I190	R:R:L194	2.85	No	No	0	5	4
132	R:R:E216	R:R:L192	10.6	Yes	No	0	3	4
133	R:R:E216	R:R:T193	7.06	Yes	No	0	3	5
134	R:R:M203	R:R:S201	7.67	No	No	0	4	4
135	R:R:H206	R:R:M203	9.19	No	No	0	5	4
136	R:R:C204	R:R:F205	5.59	No	Yes	0	9	4
137	R:R:H206	R:R:R208	10.16	No	No	0	5	5
138	R:R:D209	R:R:Y207	9.2	No	No	0	5	3
139	R:R:Q293	R:R:Y207	6.76	No	No	0	4	3
140	R:R:K302	R:R:Y207	16.72	No	No	0	4	3
141	R:R:E216	R:R:K210	5.4	Yes	No	0	3	3
142	R:R:K210	R:R:L294	5.64	No	No	0	3	1
143	R:R:A213	R:R:E216	4.53	No	Yes	0	1	3
144	R:R:F219	R:R:L223	4.87	Yes	No	0	5	5
145	R:R:N220	R:R:R286	14.46	No	Yes	1	4	6
146	R:R:I290	R:R:N220	11.33	No	No	0	5	4
147	R:R:F221	R:R:F287	6.43	No	No	0	4	6
148	R:R:F287	R:R:V224	5.24	No	No	0	6	4
149	R:R:F227	R:R:W228	16.04	No	Yes	0	8	5
150	R:R:F227	R:R:F275	4.29	No	Yes	0	8	9
151	R:R:F227	R:R:H283	21.5	No	Yes	0	8	8
152	R:R:F231	R:R:W228	6.01	Yes	Yes	0	7	5
153	R:R:F287	R:R:W228	4.01	No	Yes	0	6	5
154	R:R:I230	R:R:I234	2.94	No	Yes	0	9	8
155	R:R:F231	R:R:F275	5.36	Yes	Yes	0	7	9
156	R:R:F231	R:R:T276	5.19	Yes	No	4	7	5
157	R:R:F231	R:R:V280	3.93	Yes	No	4	7	5
158	R:R:F275	R:R:I234	3.77	Yes	Yes	0	9	8
159	R:R:I235	R:R:L272	7.14	Yes	No	0	4	7
160	R:R:V271	R:R:Y238	8.83	No	Yes	0	7	8
161	R:R:K240	R:R:K243	2.87	No	No	0	4	4
162	R:R:I241	R:R:S268	3.1	No	No	0	8	7
163	R:R:F269	R:R:G242	3.01	No	Yes	0	4	4
164	R:R:K243	R:R:N244	6.99	No	No	5	4	5
165	R:R:K243	R:R:R247	7.43	No	No	5	4	5
166	R:R:N244	R:R:R247	10.85	No	No	5	5	5
167	R:R:L245	R:R:T264	2.95	No	No	0	8	7
168	R:R:I248	R:R:Y261	6.04	No	No	0	6	6
169	R:R:F255	R:R:R252	5.34	No	No	0	3	4
170	R:R:K254	R:R:S253	6.12	No	No	0	4	3
171	R:R:F255	R:R:P256	8.67	No	No	0	3	3
172	R:R:N257	R:R:Y261	4.65	No	No	0	4	6
173	R:R:K260	R:R:T264	3	No	No	0	5	7
174	R:R:T263	R:R:T264	3.14	No	No	0	7	7
175	R:R:R266	R:R:T263	5.17	No	No	0	6	7
176	R:R:N267	R:R:R266	9.64	No	No	0	7	6
177	R:R:I274	R:R:L322	4.28	Yes	No	0	6	6
178	R:R:I274	R:R:M326	2.92	Yes	No	0	6	7
179	R:R:F275	R:R:F279	3.22	Yes	Yes	0	9	8
180	R:R:T276	R:R:V280	4.76	No	No	4	5	5
181	R:R:C278	R:R:N319	3.15	No	Yes	0	7	9
182	R:R:F279	R:R:S316	3.96	Yes	No	0	8	7
183	R:R:F279	R:R:N319	7.25	Yes	Yes	0	8	9
184	R:R:P281	R:R:V280	3.53	No	No	0	9	5
185	R:R:M312	R:R:P281	5.03	No	No	0	6	9
186	R:R:L315	R:R:P281	3.28	No	No	0	7	9
187	R:R:H283	R:R:Y282	7.62	Yes	Yes	0	8	6
188	R:R:R286	R:R:Y282	11.32	Yes	Yes	1	6	6
189	R:R:N309	R:R:Y282	10.47	Yes	Yes	1	5	6
190	R:R:S316	R:R:Y282	5.09	No	Yes	0	7	6
191	R:R:F285	R:R:I288	8.79	Yes	No	0	5	5
192	R:R:F285	R:R:V305	3.93	Yes	No	0	5	4
193	R:R:F285	R:R:T308	9.08	Yes	No	0	5	5
194	R:R:F285	R:R:N309	8.46	Yes	Yes	0	5	5
195	R:R:F285	R:R:M312	8.71	Yes	No	0	5	6
196	R:R:R286	R:R:Y289	12.35	Yes	Yes	1	6	4
197	R:R:N309	R:R:R286	4.82	Yes	Yes	1	5	6
198	R:R:Q293	R:R:Y289	13.53	No	Yes	0	4	4
199	R:R:V305	R:R:Y289	5.05	No	Yes	0	4	4
200	R:R:N309	R:R:Y289	11.63	Yes	Yes	1	5	4
201	R:R:N295	R:R:V296	2.96	No	No	0	1	1
202	R:R:S297	R:R:W301	3.71	No	Yes	0	2	1
203	R:R:C299	R:R:K302	6.47	No	No	0	7	4
204	R:R:V305	R:R:W301	7.36	No	Yes	0	4	1
205	R:R:E303	R:R:H306	3.69	Yes	No	0	1	4
206	R:R:E303	R:R:K307	8.1	Yes	No	2	1	3
207	R:R:I304	R:R:K307	4.36	No	No	0	3	3
208	R:R:E310	R:R:H306	12.31	No	No	0	5	4
209	R:R:S317	R:R:V314	3.23	No	No	0	7	5
210	R:R:C321	R:R:F318	4.19	No	No	0	7	5
211	R:R:F318	R:R:L322	3.65	No	No	0	5	6
212	R:R:D323	R:R:N319	14.81	No	Yes	0	9	9
213	R:R:V325	R:R:Y327	5.05	No	No	0	6	9
214	R:R:I89	R:R:N87	2.83	Yes	No	0	7	8
215	R:R:I91	R:R:N95	2.83	No	No	0	6	9
216	R:R:L313	R:R:M138	2.83	No	No	0	5	7
217	R:R:I274	R:R:N319	2.83	Yes	Yes	0	6	9
218	R:R:K51	R:R:L52	2.82	No	No	0	4	4
219	R:R:K214	R:R:L294	2.82	No	No	0	2	1
220	R:R:K260	R:R:N257	2.8	No	No	0	5	4
221	R:R:A75	R:R:F79	2.77	No	No	0	8	6
222	R:R:L76	R:R:L94	2.77	No	No	0	7	6
223	R:R:I166	R:R:Q170	2.74	No	No	0	7	3
224	R:R:D323	R:R:L145	2.71	No	No	0	9	8
225	R:R:C175	R:R:Y92	2.69	No	Yes	0	6	7
226	R:R:H283	R:R:M138	2.63	Yes	No	0	8	7
227	R:R:F147	R:R:V174	2.62	No	No	0	5	5
228	R:R:F221	R:R:V225	2.62	No	No	0	4	5
229	R:R:S268	R:R:Y238	2.54	No	Yes	0	7	8
230	R:R:F318	R:R:I64	2.51	No	No	0	5	7
231	R:R:I154	R:R:R158	2.51	No	No	0	6	5
232	R:R:F219	R:R:I222	2.51	Yes	No	0	5	5
233	R:R:K250	R:R:R247	2.48	No	No	0	3	5
234	R:R:K250	R:R:R251	2.48	No	No	0	3	4
235	R:R:S292	R:R:W301	2.47	No	Yes	0	3	1
236	R:R:F109	R:R:L122	2.44	No	No	0	6	7
237	R:R:I98	R:R:W179	2.35	No	No	0	5	9
238	R:R:R84	R:R:R86	2.13	No	No	0	5	7
239	R:R:G184	R:R:G185	2.11	No	No	0	3	4
240	R:R:G197	R:R:G198	2.11	No	No	0	1	1
241	R:R:G71	R:R:P324	2.03	No	No	0	8	9
242	R:R:C321	R:R:G68	1.96	No	No	0	7	8
243	R:R:A265	R:R:G242	1.95	No	Yes	0	5	4
244	R:R:G242	R:R:S268	1.86	Yes	No	0	4	7
245	R:R:G123	R:R:V124	1.84	No	No	0	7	4
246	R:R:G131	R:R:V130	1.84	No	No	0	6	5
247	R:R:G81	R:R:L80	1.71	No	No	0	4	3
248	R:R:G146	R:R:L233	1.71	No	No	0	7	7
249	R:R:G242	R:R:L245	1.71	Yes	No	0	4	8
250	R:R:C176	R:R:I172	1.64	No	No	0	4	4
251	R:R:S291	R:R:S292	1.63	No	No	0	4	3
252	R:R:S141	R:R:V96	1.62	No	No	0	9	9
253	R:R:C176	R:R:M180	1.62	No	No	0	4	4
254	R:R:A217	R:R:I290	1.62	No	No	0	4	5
255	R:R:T55	R:R:V56	1.59	No	No	0	5	5
256	R:R:A97	R:R:L76	1.58	No	No	0	9	7
257	R:R:A265	R:R:L246	1.58	No	No	0	5	3
258	R:R:A213	R:R:N212	1.56	No	No	0	1	2
259	R:R:I311	R:R:V56	1.54	No	No	0	5	5
260	R:R:I74	R:R:V78	1.54	No	No	0	5	7
261	R:R:I115	R:R:T58	1.52	No	No	0	4	5
262	R:R:I91	R:R:T168	1.52	No	No	0	6	4
263	R:R:A165	R:R:Q162	1.52	No	No	0	3	5
264	R:R:I277	R:R:T276	1.52	No	No	0	5	5
265	R:R:L246	R:R:S249	1.5	No	No	0	3	3
266	R:R:L322	R:R:V325	1.49	No	No	0	6	6
267	R:R:I156	R:R:I241	1.47	No	No	0	8	8
268	R:R:I218	R:R:I222	1.47	No	No	0	5	5
269	R:R:I235	R:R:I239	1.47	Yes	No	0	4	3
270	R:R:I270	R:R:I274	1.47	No	Yes	0	5	6
271	R:R:I273	R:R:I277	1.47	No	No	0	4	5
272	R:R:I143	R:R:M226	1.46	No	No	0	5	5
273	R:R:I230	R:R:M226	1.46	No	No	0	9	5
274	R:R:I166	R:R:K164	1.45	No	No	0	7	3
275	R:R:I235	R:R:L232	1.43	Yes	No	0	4	2
276	R:R:I234	R:R:L272	1.43	Yes	No	0	8	7
277	R:R:I235	R:R:L236	1.43	Yes	No	0	4	4
278	R:R:K196	R:R:L192	1.41	No	No	0	3	4
279	R:R:H199	R:R:S201	1.39	No	No	0	3	4
280	R:R:F255	R:R:S258	1.32	No	No	0	3	4
281	R:R:D49	R:R:E303	1.3	No	Yes	0	4	1
282	R:R:A284	R:R:W228	1.3	No	Yes	0	6	5
283	R:R:S298	R:R:Y300	1.27	No	No	0	5	2
284	R:R:S298	R:R:W301	1.24	No	Yes	0	5	1
285	R:R:Q161	R:R:R158	1.17	No	No	0	4	5
286	R:R:R252	R:R:Y261	1.03	No	No	0	4	6

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:?1	9.95	10	1	0
2	R:R:F65	4.412	5	0	7
3	R:R:I89	3.0875	4	0	7
4	R:R:Y92	4.7375	4	0	7
5	R:R:H114	7.4075	4	0	5
6	R:R:Y135	10.53	4	1	5
7	R:R:I140	4.44	4	0	7
8	R:R:Y153	8.032	5	0	7
9	R:R:F186	4.625	6	1	7
10	R:R:F205	6.5025	4	0	4
11	R:R:E216	6.33	5	0	3
12	R:R:F219	3.8425	4	0	5
13	R:R:W228	6.84	4	0	5
14	R:R:F231	5.1225	4	4	7
15	R:R:I234	3.572	5	0	8
16	R:R:I235	2.8675	4	0	4
17	R:R:Y238	6.6875	4	0	8
18	R:R:G242	2.1325	4	0	4
19	R:R:I274	2.875	4	0	6
20	R:R:F275	4.16	4	0	9
21	R:R:F279	6.12	4	0	8
22	R:R:Y282	8.092	5	1	6
23	R:R:H283	10.3875	4	0	8
24	R:R:F285	7.794	5	0	5
25	R:R:R286	10.1267	6	1	6
26	R:R:Y289	10.802	5	1	4
27	R:R:W301	3.695	4	0	1
28	R:R:E303	4.225	4	2	1
29	R:R:N309	8.845	4	1	5
30	R:R:N319	7.01	4	0	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:F205	42.0047	3.66	Yes	Yes	0	0	4
2	R:R:F205	R:R:R110	29.1321	12.83	Yes	No	0	4	7
3	R:R:H114	R:R:R110	28.1383	11.28	Yes	No	0	5	7
4	R:R:H114	R:R:L57	19.1633	7.71	Yes	No	0	5	5
5	R:R:L53	R:R:L57	13.6426	5.54	No	No	0	5	5
6	L:L:?1	R:R:T132	65.6809	4.43	Yes	No	1	0	5
7	R:R:F186	R:R:T132	54.7859	6.49	Yes	No	1	7	5
8	R:R:F186	R:R:L133	41.2404	3.65	Yes	No	0	7	5
9	R:R:L133	R:R:N137	39.1036	8.24	No	No	0	5	8
10	R:R:L103	R:R:N137	36.9556	8.24	No	No	0	7	8
11	R:R:F134	R:R:L103	35.8774	4.87	No	No	0	7	7
12	R:R:F134	R:R:Y61	34.7949	6.19	No	No	0	7	8
13	R:R:L107	R:R:Y61	30.5552	11.72	No	No	0	7	8
14	R:R:F65	R:R:L107	29.46	3.65	Yes	No	0	7	7
15	R:R:F65	R:R:L69	23.9422	3.65	Yes	No	0	7	6
16	L:L:?1	R:R:Y135	53.8893	29.06	Yes	Yes	1	0	5
17	R:R:Y135	R:R:Y282	37.4426	5.96	Yes	Yes	1	5	6
18	R:R:S316	R:R:Y282	47.8435	5.09	No	Yes	0	7	6
19	R:R:F279	R:R:S316	47.5719	3.96	Yes	No	0	8	7
20	L:L:?1	R:R:R286	38.9277	13.69	Yes	Yes	1	0	6
21	R:R:R286	R:R:Y282	42.0596	11.32	Yes	Yes	1	6	6
22	R:R:I73	R:R:L69	22.8302	4.28	No	No	0	3	6
23	R:R:I73	R:R:L101	21.7153	2.85	No	No	0	3	7
24	R:R:L101	R:R:N72	19.4772	4.12	No	No	0	7	9
25	R:R:D100	R:R:N72	11.5551	14.81	No	No	0	9	9
26	R:R:Y135	R:R:Y139	17.2152	2.98	Yes	No	0	5	7
27	R:R:H283	R:R:Y139	36.5981	9.8	Yes	No	0	8	7
28	R:R:F227	R:R:H283	73.8465	21.5	No	Yes	0	8	8
29	R:R:F227	R:R:F275	66.8478	4.29	No	Yes	0	8	9
30	R:R:F275	R:R:I234	100	3.77	Yes	Yes	0	9	8
31	R:R:I234	R:R:S149	91.3319	6.19	Yes	No	0	8	9
32	R:R:S149	R:R:Y238	90.2185	5.09	No	Yes	0	9	8
33	R:R:R152	R:R:Y238	41.5374	10.29	No	Yes	0	9	8
34	R:R:I89	R:R:R152	22.6669	3.76	Yes	No	0	7	9
35	R:R:I89	R:R:N87	14.2366	2.83	Yes	No	0	7	8
36	R:R:N87	R:R:Q90	12.9233	17.17	No	No	0	8	7
37	R:R:Q90	R:R:R86	10.4093	3.5	No	No	0	7	7
38	L:L:?1	R:R:L223	18.551	8.32	Yes	No	0	0	5
39	R:R:L223	R:R:Y139	20.0008	5.86	No	No	0	5	7
40	R:R:H283	R:R:Y282	39.4471	7.62	Yes	Yes	0	8	6
41	R:R:F275	R:R:F279	36.7205	3.22	Yes	Yes	0	9	8
42	R:R:I148	R:R:R152	18.1118	5.01	No	No	0	9	9
43	R:R:I148	R:R:Y92	13.3921	4.84	No	Yes	0	9	7
44	R:R:C175	R:R:Y92	12.2069	2.69	No	Yes	0	6	7
45	R:R:C175	R:R:N95	10.4713	7.87	No	No	0	6	9
46	R:R:F205	R:R:V130	10.3924	3.93	Yes	No	0	4	5
47	R:R:I190	R:R:L194	15.8033	2.85	No	No	0	5	4
48	R:R:I125	R:R:L194	13.554	5.71	No	No	0	1	4
49	R:R:I125	R:R:V124	11.3018	3.07	No	No	0	1	4
50	L:L:?1	R:R:M189	13.8946	4.25	Yes	No	0	0	4
51	R:R:E216	R:R:M189	12.9346	4.06	Yes	No	0	3	4
52	R:R:S268	R:R:Y238	50.3139	2.54	No	Yes	0	7	8
53	R:R:I241	R:R:S268	26.8039	3.1	No	No	0	8	7
54	R:R:I241	R:R:Y153	24.3743	4.84	No	Yes	0	8	7
55	R:R:R163	R:R:Y153	12.7755	3.09	No	Yes	0	5	7
56	R:R:K164	R:R:R163	11.596	4.95	No	No	0	3	5
57	R:R:G242	R:R:S268	23.3327	1.86	Yes	No	0	4	7
58	R:R:G242	R:R:L245	16.9069	1.71	Yes	No	0	4	8
59	R:R:L245	R:R:T264	15.6105	2.95	No	No	0	8	7
60	R:R:K260	R:R:T264	10.4107	3	No	No	0	5	7

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?1	R:R:T132	4.43	1	Yes	No	0	5	0	1
L:L:?1	R:R:Y135	29.06	1	Yes	Yes	0	5	0	1
L:L:?1	R:R:L181	4.16	1	Yes	No	0	4	0	1
L:L:?1	R:R:M189	4.25	1	Yes	No	0	4	0	1
L:L:?1	R:R:F205	3.66	1	Yes	Yes	0	4	0	1
L:L:?1	R:R:R208	9.13	1	Yes	No	0	5	0	1
L:L:?1	R:R:N220	11.35	1	Yes	No	0	4	0	1
L:L:?1	R:R:L223	8.32	1	Yes	No	0	5	0	1
L:L:?1	R:R:R286	13.69	1	Yes	Yes	0	6	0	1
L:L:?1	R:R:Y289	11.45	1	Yes	Yes	0	4	0	1
R:R:F205	R:R:R110	12.83	0	Yes	No	4	7	1	2
R:R:T132	R:R:V129	6.35	1	No	No	5	5	1	2
R:R:F186	R:R:V129	5.24	1	Yes	No	7	5	2	2
R:R:F205	R:R:V130	3.93	0	Yes	No	4	5	1	2
R:R:F186	R:R:T132	6.49	1	Yes	No	7	5	2	1
R:R:Y135	R:R:Y139	2.98	1	Yes	No	5	7	1	2
R:R:Y135	R:R:Y282	5.96	1	Yes	Yes	5	6	1	2
R:R:R286	R:R:Y135	4.12	1	Yes	Yes	6	5	1	1
R:R:L223	R:R:Y139	5.86	0	No	No	5	7	1	2
R:R:E216	R:R:M189	4.06	0	Yes	No	3	4	2	1
R:R:F219	R:R:M189	4.98	0	Yes	No	5	4	2	1
R:R:C204	R:R:F205	5.59	0	No	Yes	9	4	2	1
R:R:H206	R:R:R208	10.16	0	No	No	5	5	2	1
R:R:F219	R:R:L223	4.87	0	Yes	No	5	5	2	1
R:R:N220	R:R:R286	14.46	1	No	Yes	4	6	1	1
R:R:I290	R:R:N220	11.33	0	No	No	5	4	2	1
R:R:R286	R:R:Y282	11.32	1	Yes	Yes	6	6	1	2
R:R:N309	R:R:Y282	10.47	1	Yes	Yes	5	6	2	2
R:R:R286	R:R:Y289	12.35	1	Yes	Yes	6	4	1	1
R:R:N309	R:R:R286	4.82	1	Yes	Yes	5	6	2	1
R:R:Q293	R:R:Y289	13.53	0	No	Yes	4	4	2	1
R:R:V305	R:R:Y289	5.05	0	No	Yes	4	4	2	1
R:R:N309	R:R:Y289	11.63	1	Yes	Yes	5	4	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	8K4N_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	2.85
Number of Linked Nodes	267
Number of Links	286
Number of Hubs	30
Number of Links mediated by Hubs	118
Number of Communities	5
Number of Nodes involved in Communities	23
Number of Links involved in Communities	30

Path Summary
Number Of Nodes in MetaPath	61
Number Of Links MetaPath	60
Number of Shortest Paths	111896
Length Of Smallest Path	3
Average Path Length	17.2107
Length of Longest Path	38
Minimum Path Strength	1.255
Average Path Strength	6.72142
Maximum Path Strength	20.85
Minimum Path Correlation	0.7
Average Path Correlation	0.928357
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	3.0303
Average % Of Corr. Nodes	39.8437
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	42.0581
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain • Ras-like P-loop GTPases
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain • Ras-like P-loop GTPases
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	VF0
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	VF0
Name	(2R)-2-azanyl-3-[oxidanyl-[(2R)-2-oxidanyl-3-tetradec-9-enoyloxy-propoxy]phosphoryl]oxy-propanoic acid
Synonyms
Identifier
Formula	C20 H38 N O9 P
Molecular Weight	467.491
SMILES
PubChem	168719765
Formal Charge	0
Total Atoms	69
Total Chiral Atoms	2
Total Bonds	68
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q9UPC5
Sequence	>8K4N_nogp_Chain_R D E K L L S T V L T T S Y S V I F I V G L V G N I I A L Y V F L G I H R K R N S I Q I Y L L N V A I A D L L L I F C L P F R I M Y H I N Q N K W T L G V I L C K V V G T L F Y M N M Y I S I I L L G F I S L D R Y I K I N R S I Q Q R K A I T T K Q S I Y V C C I V W M L A L G G F L T M I I L T L K K G G H N S T M C F H Y R D K H N A K G E A I F N F I L V V M F W L I F L L I I L S Y I K I G K N L L R I S K R R S K F P N S G K Y A T T A R N S F I V L I I F T I C F V P Y H A F R F I Y I S S Q L N V S S C Y W K E I V H K T N E I M L V L S S F N S C L D P V M Y Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8XBE	A	Orphan	Orphan	GPR34	Homo sapiens	S3E-LysoPS	-	Gi1/β1/γ1	3.4	2024-05-15	doi.org/10.1038/s41467-024-45046-z
	8XBE (No Gprot)	A	Orphan	Orphan	GPR34	Homo sapiens	S3E-LysoPS	-		3.4	2024-05-15	doi.org/10.1038/s41467-024-45046-z
	8XBG	A	Orphan	Orphan	GPR34	Homo sapiens	S3E-LysoPS	-	-	3.43	2024-05-15	doi.org/10.1038/s41467-024-45046-z
	8SAI	A	Orphan	Orphan	GPR34	Homo sapiens	1-Oleoyl-2-Hydroxy-Sn-Glycero-3-Phospho-L-Serine	-	Gi1/β1/γ2	3.27	2023-10-04	doi.org/10.1073/pnas.2308435120
	8SAI (No Gprot)	A	Orphan	Orphan	GPR34	Homo sapiens	1-Oleoyl-2-Hydroxy-Sn-Glycero-3-Phospho-L-Serine	-		3.27	2023-10-04	doi.org/10.1073/pnas.2308435120
	8IYX	A	Orphan	Orphan	GPR34	Homo sapiens	YL-365	-	-	3.34	2024-03-20	doi.org/10.1073/pnas.2308435120
	8WRB	A	Orphan	Orphan	GPR34	Homo sapiens	Lysophosphatidylserine	-	Gi1/β1/γ2	2.91	2023-11-08	doi.org/10.1371/journal.pbio.3002387
	8WRB (No Gprot)	A	Orphan	Orphan	GPR34	Homo sapiens	Lysophosphatidylserine	-		2.91	2023-11-08	doi.org/10.1371/journal.pbio.3002387
	8XBH	A	Orphan	Orphan	GPR34	Homo sapiens	S3E-LysoPS	-	Gi1/β1/γ2	2.83	2023-12-27	doi.org/10.1038/s41467-024-45046-z
	8XBH (No Gprot)	A	Orphan	Orphan	GPR34	Homo sapiens	S3E-LysoPS	-		2.83	2023-12-27	doi.org/10.1038/s41467-024-45046-z
	8XBI	A	Orphan	Orphan	GPR34	Homo sapiens	S3E-LysoPS	-	-	3.06	2023-12-27	doi.org/10.1038/s41467-024-45046-z
	8K4N	A	Orphan	Orphan	GPR34	Homo sapiens	VF0	-	Gi1/β1/γ2	2.83	2023-10-25	To be published
	8K4N (No Gprot)	A	Orphan	Orphan	GPR34	Homo sapiens	VF0	-		2.83	2023-10-25	To be published
	8IZ4	A	Orphan	Orphan	GPR34	Homo sapiens	Lysophosphatidylserine	-	Gi1/β1/γ2	2.94	2024-04-10	To be published
	8IZ4 (No Gprot)	A	Orphan	Orphan	GPR34	Homo sapiens	Lysophosphatidylserine	-		2.94	2024-04-10	To be published

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 8K4N_nogp.zip

You can click to copy the link of this page to easily come back here later

or use this QR code to link and share this page.

You can also read or download a guide explaining the meaning of all files and numerical data.