psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:C94	8.02	Yes	No	0	0	9
2	L:L:?1	R:R:V99	5.27	Yes	No	0	0	6
3	L:L:?1	R:R:Y102	24.28	Yes	Yes	1	0	5
4	L:L:?1	R:R:N156	13.18	Yes	No	0	0	5
5	L:L:?1	R:R:K176	5.7	Yes	No	1	0	4
6	L:L:?1	R:R:H184	14.94	Yes	No	1	0	3
7	L:L:?1	R:R:N188	6.24	Yes	No	1	0	4
8	L:L:?1	R:R:F191	4.92	Yes	Yes	0	0	5
9	L:L:?1	R:R:R253	9.21	Yes	Yes	1	0	6
10	L:L:?1	R:R:Y256	4.74	Yes	Yes	1	0	5
11	L:L:?1	R:R:Q260	8.74	Yes	No	1	0	3
12	L:L:?1	R:R:K277	7.12	Yes	Yes	1	0	5
13	L:L:?1	R:R:E278	8.03	Yes	No	1	0	5
14	R:R:Q16	R:R:Y275	10.15	No	Yes	0	3	2
15	R:R:E271	R:R:N17	10.52	No	No	1	2	5
16	R:R:N17	R:R:Y275	6.98	No	Yes	1	5	2
17	R:R:L18	R:R:Q22	6.65	No	No	0	3	4
18	R:R:L19	R:R:Q23	5.32	No	No	0	3	3
19	R:R:I20	R:R:I24	4.42	No	No	0	4	6
20	R:R:R274	R:R:T21	11.64	Yes	No	0	3	4
21	R:R:F279	R:R:I25	5.02	No	No	0	5	6
22	R:R:L28	R:R:L282	11.07	No	No	0	5	5
23	R:R:K77	R:R:Y29	21.5	No	Yes	0	7	8
24	R:R:L282	R:R:Y29	11.72	No	Yes	0	5	8
25	R:R:A285	R:R:Y29	5.34	No	Yes	0	7	8
26	R:R:F33	R:R:I37	11.3	No	Yes	0	7	7
27	R:R:F33	R:R:F74	5.36	No	Yes	0	7	8
28	R:R:F33	R:R:P75	7.22	No	No	0	7	9
29	R:R:I37	R:R:L38	5.71	Yes	No	0	7	4
30	R:R:F68	R:R:I37	5.02	No	Yes	0	7	7
31	R:R:I37	R:R:S71	6.19	Yes	No	0	7	6
32	R:R:L39	R:R:P292	11.49	No	No	0	8	9
33	R:R:D67	R:R:N40	8.08	Yes	No	3	9	9
34	R:R:N40	R:R:V288	4.43	No	Yes	3	9	8
35	R:R:N40	R:R:P292	4.89	No	No	0	9	9
36	R:R:F296	R:R:S43	5.28	Yes	No	0	7	8
37	R:R:I46	R:R:W45	4.7	Yes	No	0	7	4
38	R:R:K309	R:R:W45	8.12	No	No	0	4	4
39	R:R:F302	R:R:I46	10.05	No	Yes	0	9	7
40	R:R:I305	R:R:I46	4.42	No	Yes	0	5	7
41	R:R:I46	R:R:L306	7.14	Yes	No	0	7	7
42	R:R:F47	R:R:V50	9.18	Yes	No	0	7	5
43	R:R:F47	R:R:L60	7.31	Yes	Yes	2	7	8
44	R:R:F47	R:R:K61	4.96	Yes	No	0	7	6
45	R:R:F296	R:R:F47	11.79	Yes	Yes	2	7	7
46	R:R:F302	R:R:F47	15	No	Yes	2	9	7
47	R:R:I57	R:R:V50	4.61	No	No	0	7	5
48	R:R:K54	R:R:S53	7.65	No	No	0	8	5
49	R:R:I57	R:R:K54	4.36	No	No	0	7	8
50	R:R:S55	R:R:Y59	10.17	No	Yes	0	7	7
51	R:R:S55	R:R:V135	4.85	No	No	0	7	3
52	R:R:S138	R:R:S55	6.52	No	No	0	8	7
53	R:R:F56	R:R:L60	12.18	No	Yes	2	8	8
54	R:R:F56	R:R:I115	7.54	No	No	2	8	9
55	R:R:F56	R:R:R119	7.48	No	Yes	2	8	9
56	R:R:I58	R:R:Y59	4.84	Yes	Yes	0	6	7
57	R:R:I58	R:R:S138	6.19	Yes	No	0	6	8
58	R:R:F111	R:R:Y59	5.16	No	Yes	2	8	7
59	R:R:L114	R:R:Y59	12.89	No	Yes	2	7	7
60	R:R:I115	R:R:Y59	4.84	No	Yes	2	9	7
61	R:R:Q133	R:R:Y59	18.04	Yes	Yes	2	7	7
62	R:R:F296	R:R:L60	8.53	Yes	Yes	2	7	8
63	R:R:F111	R:R:N62	13.29	No	No	2	8	9
64	R:R:N62	R:R:S142	8.94	No	No	0	9	7
65	R:R:N62	R:R:W146	7.91	No	Yes	2	9	9
66	R:R:D67	R:R:I63	4.2	Yes	No	0	9	9
67	R:R:F112	R:R:I63	8.79	Yes	No	0	9	9
68	R:R:F296	R:R:I63	5.02	Yes	No	0	7	9
69	R:R:F296	R:R:V64	7.87	Yes	No	0	7	9
70	R:R:D67	R:R:V288	5.84	Yes	Yes	3	9	8
71	R:R:D291	R:R:D67	7.98	No	Yes	0	9	9
72	R:R:F68	R:R:L72	6.09	No	No	0	7	4
73	R:R:L100	R:R:V69	4.47	No	No	0	5	7
74	R:R:N104	R:R:V69	10.35	No	No	0	8	7
75	R:R:F101	R:R:M70	9.95	Yes	Yes	0	7	7
76	R:R:M70	R:R:N104	5.61	Yes	No	0	7	8
77	R:R:M105	R:R:M70	4.33	No	Yes	0	8	7
78	R:R:M70	R:R:V288	6.09	Yes	Yes	0	7	8
79	R:R:L100	R:R:T73	4.42	No	No	0	5	7
80	R:R:F101	R:R:F74	6.43	Yes	Yes	0	7	8
81	R:R:A285	R:R:F74	4.16	No	Yes	0	7	8
82	R:R:F74	R:R:V288	5.24	Yes	Yes	0	8	8
83	R:R:F76	R:R:F92	6.43	No	No	0	6	3
84	R:R:D81	R:R:K77	12.44	No	No	0	5	7
85	R:R:L79	R:R:L89	4.15	No	No	0	4	7
86	R:R:L84	R:R:S82	4.5	No	No	0	3	4
87	R:R:L89	R:R:P86	8.21	No	No	0	7	4
88	R:R:Q88	R:R:V167	5.73	No	No	0	2	2
89	R:R:I170	R:R:V91	4.61	No	No	0	3	3
90	R:R:F92	R:R:V96	9.18	No	No	0	3	4
91	R:R:S97	R:R:V93	4.85	No	No	0	5	6
92	R:R:C172	R:R:C94	7.28	No	No	0	9	9
93	R:R:R95	R:R:T160	10.35	No	No	0	8	5
94	R:R:N161	R:R:R95	4.82	No	No	0	4	8
95	R:R:I157	R:R:V99	7.68	No	No	0	5	6
96	R:R:F101	R:R:Y102	5.16	Yes	Yes	1	7	5
97	R:R:F101	R:R:L281	7.31	Yes	No	1	7	6
98	R:R:Y102	R:R:Y249	6.95	Yes	Yes	1	5	7
99	R:R:L281	R:R:Y102	8.21	No	Yes	1	6	5
100	R:R:M105	R:R:Y106	7.18	No	No	0	8	8
101	R:R:F191	R:R:Y106	23.73	Yes	No	0	5	8
102	R:R:H250	R:R:Y106	9.8	Yes	No	0	8	8
103	R:R:V107	R:R:W146	12.26	No	Yes	0	7	9
104	R:R:F195	R:R:I109	11.3	Yes	No	1	9	8
105	R:R:F246	R:R:I109	15.07	Yes	No	1	9	8
106	R:R:F111	R:R:W146	5.01	No	Yes	2	8	9
107	R:R:F112	R:R:F242	5.36	Yes	Yes	0	9	9
108	R:R:D291	R:R:F112	10.75	No	Yes	0	9	9
109	R:R:F112	R:R:Y295	13.41	Yes	No	0	9	9
110	R:R:L114	R:R:Q133	10.65	No	Yes	2	7	7
111	R:R:L114	R:R:L141	5.54	No	No	0	7	6
112	R:R:I115	R:R:R119	7.52	No	Yes	2	9	9
113	R:R:L202	R:R:S116	9.01	No	No	2	8	9
114	R:R:S116	R:R:Y206	5.09	No	Yes	2	9	9
115	R:R:F117	R:R:W128	7.02	Yes	No	0	6	4
116	R:R:F117	R:R:I132	17.58	Yes	No	0	6	3
117	R:R:F117	R:R:Q133	16.4	Yes	Yes	0	6	7
118	R:R:F117	R:R:F205	10.72	Yes	Yes	0	6	8
119	R:R:D118	R:R:K122	4.15	No	No	0	8	8
120	R:R:D118	R:R:Q133	7.83	No	Yes	0	8	7
121	R:R:R119	R:R:Y206	8.23	Yes	Yes	2	9	9
122	R:R:I238	R:R:R119	5.01	No	Yes	2	8	9
123	R:R:R119	R:R:Y295	8.23	Yes	No	0	9	9
124	R:R:V124	R:R:Y120	11.36	No	Yes	0	8	8
125	R:R:F205	R:R:Y120	16.5	Yes	Yes	0	8	8
126	R:R:P126	R:R:Y121	9.74	No	No	4	7	6
127	R:R:W128	R:R:Y121	13.5	No	No	4	4	6
128	R:R:F131	R:R:Y121	34.04	No	No	0	4	6
129	R:R:P126	R:R:W128	18.92	No	No	4	7	4
130	R:R:S130	R:R:T129	4.8	No	No	0	5	6
131	R:R:F131	R:R:S134	7.93	No	No	0	4	7
132	R:R:S134	R:R:Y137	6.36	No	No	0	7	3
133	R:R:S136	R:R:Y137	5.09	No	No	0	4	3
134	R:R:I190	R:R:L152	7.14	No	No	0	5	5
135	R:R:F191	R:R:L152	9.74	Yes	No	0	5	5
136	R:R:I158	R:R:V154	6.14	No	No	0	4	5
137	R:R:P155	R:R:W183	12.16	No	No	0	7	2
138	R:R:N156	R:R:S187	5.96	No	No	0	5	4
139	R:R:L159	R:R:L179	5.54	No	No	0	5	2
140	R:R:G180	R:R:L159	5.13	No	No	0	3	5
141	R:R:K176	R:R:T160	6.01	No	No	0	4	5
142	R:R:Q162	R:R:S177	4.33	No	No	0	5	3
143	R:R:I170	R:R:V164	6.14	No	No	0	3	2
144	R:R:Q169	R:R:T168	12.76	No	No	0	1	3
145	R:R:E174	R:R:K171	20.25	No	No	0	5	3
146	R:R:I173	R:R:R181	6.26	No	No	0	4	2
147	R:R:I173	R:R:Q260	5.49	No	No	0	4	3
148	R:R:H184	R:R:K176	5.24	No	No	1	3	4
149	R:R:S187	R:R:W183	6.18	No	No	0	4	2
150	R:R:K185	R:R:T261	10.51	No	No	0	3	1
151	R:R:N188	R:R:R253	19.28	No	Yes	1	4	6
152	R:R:N188	R:R:T257	13.16	No	No	1	4	5
153	R:R:I254	R:R:Y189	8.46	No	Yes	0	5	4
154	R:R:I254	R:R:V192	9.22	No	No	0	5	5
155	R:R:I194	R:R:I197	4.42	No	No	0	6	6
156	R:R:F195	R:R:W196	11.02	Yes	Yes	0	9	4
157	R:R:F195	R:R:F242	5.36	Yes	Yes	1	9	9
158	R:R:F195	R:R:F246	6.43	Yes	Yes	1	9	9
159	R:R:F195	R:R:H250	35.07	Yes	Yes	1	9	8
160	R:R:F199	R:R:W196	6.01	No	Yes	0	7	4
161	R:R:F199	R:R:I203	7.54	No	No	0	7	4
162	R:R:F199	R:R:F242	7.5	No	Yes	0	7	9
163	R:R:F205	R:R:L201	7.31	Yes	No	0	8	7
164	R:R:L202	R:R:Y206	7.03	No	Yes	2	8	9
165	R:R:I235	R:R:Y206	6.04	No	Yes	0	8	9
166	R:R:I238	R:R:Y206	6.04	No	Yes	2	8	9
167	R:R:V239	R:R:Y206	5.05	No	Yes	0	8	9
168	R:R:I235	R:R:T210	6.08	No	No	0	8	5
169	R:R:K211	R:R:K215	15.8	No	No	0	4	5
170	R:R:I213	R:R:S231	4.64	No	No	0	8	8
171	R:R:F214	R:R:S232	7.93	No	No	0	4	6
172	R:R:H217	R:R:S216	4.18	Yes	No	0	4	5
173	R:R:H217	R:R:S224	5.58	Yes	Yes	0	4	4
174	R:R:N223	R:R:V227	4.43	No	No	0	1	5
175	R:R:L298	R:R:N234	9.61	No	No	0	7	8
176	R:R:F240	R:R:V244	9.18	No	No	0	5	6
177	R:R:L290	R:R:V241	4.47	No	No	5	7	7
178	R:R:I294	R:R:V241	4.61	Yes	No	5	8	7
179	R:R:F242	R:R:F246	9.65	Yes	Yes	1	9	9
180	R:R:F243	R:R:V247	19.66	No	No	0	7	5
181	R:R:C245	R:R:N287	11.02	No	Yes	0	9	9
182	R:R:F246	R:R:H250	4.53	Yes	Yes	1	9	8
183	R:R:F246	R:R:S284	5.28	Yes	No	0	9	8
184	R:R:F246	R:R:N287	8.46	Yes	Yes	0	9	9
185	R:R:H250	R:R:Y249	13.07	Yes	Yes	1	8	7
186	R:R:R253	R:R:Y249	13.38	Yes	Yes	1	6	7
187	R:R:T280	R:R:Y249	8.74	No	Yes	0	7	7
188	R:R:L281	R:R:Y249	10.55	No	Yes	1	6	7
189	R:R:R253	R:R:T257	7.76	Yes	No	1	6	5
190	R:R:K277	R:R:R253	4.95	Yes	Yes	1	5	6
191	R:R:L273	R:R:P255	4.93	No	No	0	4	5
192	R:R:Q260	R:R:Y256	16.91	No	Yes	1	3	5
193	R:R:R274	R:R:Y256	7.2	Yes	Yes	1	3	5
194	R:R:K277	R:R:Y256	14.33	Yes	Yes	1	5	5
195	R:R:E262	R:R:K258	9.45	No	No	6	1	3
196	R:R:K258	R:R:Y265	7.17	No	Yes	6	3	1
197	R:R:S259	R:R:Y265	11.45	No	Yes	0	3	1
198	R:R:K270	R:R:S259	4.59	No	No	0	3	3
199	R:R:E262	R:R:H264	4.92	No	No	0	1	1
200	R:R:E262	R:R:Y265	6.73	No	Yes	6	1	1
201	R:R:S269	R:R:Y265	5.09	No	Yes	0	1	1
202	R:R:E271	R:R:R274	9.3	No	Yes	1	2	3
203	R:R:E271	R:R:Y275	13.47	No	Yes	1	2	2
204	R:R:R274	R:R:Y275	7.2	Yes	Yes	1	3	2
205	R:R:E278	R:R:K277	10.8	No	Yes	1	5	5
206	R:R:D291	R:R:N287	10.77	No	Yes	0	9	9
207	R:R:I294	R:R:L290	4.28	Yes	No	5	8	7
208	R:R:F296	R:R:P292	5.78	Yes	No	0	7	9
209	R:R:F296	R:R:F302	6.43	Yes	No	2	7	9
210	R:R:F297	R:R:R303	6.41	No	No	0	8	8
211	R:R:C299	R:R:P301	5.65	No	No	0	8	6
212	R:R:P301	R:R:Q300	4.74	No	No	0	6	5
213	R:R:I305	R:R:K308	8.72	No	No	0	5	6
214	R:R:F48	R:R:Y49	4.13	No	No	0	4	5
215	R:R:G85	R:R:P86	4.06	No	No	0	4	4
216	R:R:F76	R:R:S97	3.96	No	No	0	6	5
217	R:R:F236	R:R:S232	3.96	No	No	0	5	6
218	R:R:F74	R:R:V32	3.93	Yes	No	0	8	7
219	R:R:F205	R:R:V204	3.93	Yes	No	0	8	4
220	R:R:F236	R:R:T210	3.89	No	No	0	5	5
221	R:R:W45	R:R:Y49	3.86	No	No	0	4	5
222	R:R:F279	R:R:I20	3.77	No	No	0	5	4
223	R:R:T257	R:R:Y189	3.75	No	Yes	0	5	4
224	R:R:G113	R:R:S116	3.71	No	No	0	7	9
225	R:R:K229	R:R:R233	3.71	No	No	0	5	5
226	R:R:G44	R:R:V64	3.68	No	No	0	7	9
227	R:R:V247	R:R:W196	3.68	No	Yes	0	5	4
228	R:R:I209	R:R:Y120	3.63	No	Yes	0	8	8
229	R:R:A35	R:R:C289	3.61	No	No	0	5	8
230	R:R:K185	R:R:Y189	3.58	No	Yes	0	3	4
231	R:R:K258	R:R:Y189	3.58	No	Yes	0	3	4
232	R:R:P26	R:R:S82	3.56	No	No	0	5	4
233	R:R:P51	R:R:V50	3.53	No	No	0	6	5
234	R:R:P155	R:R:V154	3.53	No	No	0	7	5
235	R:R:P248	R:R:V247	3.53	No	No	0	9	5
236	R:R:I25	R:R:P26	3.39	No	No	0	6	5
237	R:R:G80	R:R:N90	3.39	No	No	0	5	7
238	R:R:I254	R:R:P255	3.39	No	No	0	5	5
239	R:R:L159	R:R:P155	3.28	No	No	0	5	7
240	R:R:C30	R:R:I78	3.27	No	No	0	4	7
241	R:R:S142	R:R:V143	3.23	No	No	0	7	3
242	R:R:A252	R:R:M276	3.22	No	No	0	5	5
243	R:R:S97	R:R:T73	3.2	No	No	0	5	7
244	L:L:?1	R:R:A98	3.18	Yes	No	0	0	6
245	R:R:C299	R:R:L60	3.17	No	Yes	0	8	8
246	R:R:A66	R:R:N104	3.13	No	No	0	8	8
247	R:R:I58	R:R:S52	3.1	Yes	No	0	6	6
248	R:R:I109	R:R:V198	3.07	No	No	1	8	9
249	R:R:K230	R:R:S226	3.06	No	No	0	7	4
250	R:R:M149	R:R:V107	3.04	No	No	0	8	7
251	R:R:F68	R:R:G41	3.01	No	No	0	7	4
252	R:R:L150	R:R:V103	2.98	No	No	0	3	6
253	R:R:N287	R:R:V241	2.96	Yes	No	0	9	7
254	R:R:D67	R:R:S108	2.94	Yes	No	0	9	9
255	R:R:I293	R:R:I294	2.94	No	Yes	0	7	8
256	R:R:I58	R:R:K139	2.91	Yes	No	0	6	5
257	R:R:I173	R:R:K171	2.91	No	No	0	4	3
258	R:R:I24	R:R:L19	2.85	No	No	0	6	3
259	R:R:I144	R:R:L140	2.85	No	No	0	2	3
260	R:R:I144	R:R:L141	2.85	No	No	0	2	6
261	R:R:I170	R:R:N90	2.83	No	No	0	3	7
262	R:R:L148	R:R:M149	2.83	No	No	0	4	8
263	R:R:A153	R:R:F191	2.77	No	Yes	0	7	5
264	R:R:H217	R:R:V227	2.77	Yes	No	0	4	5
265	R:R:A208	R:R:Y120	2.67	No	Yes	0	4	8
266	R:R:R222	R:R:S221	2.64	No	No	0	2	3
267	R:R:H217	R:R:K228	2.62	Yes	No	0	4	6
268	R:R:I20	R:R:Y275	2.42	No	Yes	0	4	2
269	R:R:I25	R:R:Y29	2.42	No	Yes	0	6	8
270	R:R:N234	R:R:R233	2.41	No	No	0	8	5
271	R:R:I65	R:R:W146	2.35	No	Yes	0	5	9
272	R:R:I251	R:R:W196	2.35	No	Yes	0	5	4
273	R:R:Q88	R:R:W87	2.19	No	No	0	2	9
274	R:R:C289	R:R:G36	1.96	No	No	0	8	8
275	R:R:G36	R:R:S71	1.86	No	No	0	8	6
276	R:R:G83	R:R:S82	1.86	No	No	0	5	4
277	R:R:G180	R:R:S177	1.86	No	No	0	3	3
278	R:R:C245	R:R:V244	1.71	No	No	0	9	6
279	R:R:A286	R:R:V32	1.7	No	No	0	4	7
280	R:R:A153	R:R:V103	1.7	No	No	0	7	6
281	R:R:D81	R:R:G80	1.68	No	No	0	5	5
282	R:R:K125	R:R:P126	1.67	No	No	0	6	7
283	R:R:G83	R:R:Q22	1.64	No	No	0	5	4
284	R:R:S220	R:R:S224	1.63	No	Yes	0	4	4
285	R:R:S221	R:R:S224	1.63	No	Yes	0	3	4
286	R:R:S231	R:R:S232	1.63	No	No	0	8	6
287	R:R:V110	R:R:V145	1.6	No	No	0	6	7
288	R:R:V110	R:R:V198	1.6	No	No	1	6	9
289	R:R:S224	R:R:T225	1.6	Yes	No	0	4	3
290	R:R:S226	R:R:T225	1.6	No	No	0	4	3
291	R:R:C172	R:R:L175	1.59	No	No	0	9	5
292	R:R:I213	R:R:S216	1.55	No	No	0	8	5
293	R:R:I238	R:R:S237	1.55	No	No	0	8	6
294	R:R:I294	R:R:S237	1.55	Yes	No	0	8	6
295	R:R:I46	R:R:V42	1.54	Yes	No	0	7	7
296	R:R:I194	R:R:V110	1.54	No	No	1	6	6
297	R:R:I194	R:R:V198	1.54	No	No	1	6	9
298	R:R:K212	R:R:S216	1.53	No	No	0	5	5
299	R:R:I203	R:R:T207	1.52	No	No	0	4	4
300	R:R:L89	R:R:V93	1.49	No	No	0	7	6
301	R:R:L200	R:R:V204	1.49	No	No	0	3	4
302	R:R:I123	R:R:I209	1.47	No	No	0	8	8
303	R:R:I123	R:R:I213	1.47	No	No	0	8	8
304	R:R:I34	R:R:L38	1.43	No	No	0	5	4
305	R:R:E166	R:R:V164	1.43	No	No	0	2	2
306	R:R:L150	R:R:M147	1.41	No	No	0	3	4
307	R:R:L151	R:R:M147	1.41	No	No	0	4	4
308	R:R:C307	R:R:R303	1.39	No	No	0	4	8
309	R:R:I272	R:R:Q16	1.37	No	No	0	1	3
310	R:R:E304	R:R:Q300	1.27	No	No	0	5	5
311	R:R:I78	R:R:Y29	1.21	No	Yes	0	7	8
312	R:R:Q300	R:R:R303	1.17	No	No	0	5	8
313	R:R:E178	R:R:R181	1.16	No	No	0	2	2

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:?1	8.82643	14	1	0
2	R:R:Y29	8.438	5	0	8
3	R:R:I37	7.055	4	0	7
4	R:R:I46	5.57	5	0	7
5	R:R:F47	9.648	5	2	7
6	R:R:I58	4.26	4	0	6
7	R:R:Y59	9.32333	6	2	7
8	R:R:L60	7.7975	4	2	8
9	R:R:D67	5.808	5	3	9
10	R:R:M70	6.495	4	0	7
11	R:R:F74	5.024	5	0	8
12	R:R:F101	7.2125	4	1	7
13	R:R:Y102	11.15	4	1	5
14	R:R:F112	9.5775	4	0	9
15	R:R:F117	12.93	4	0	6
16	R:R:R119	7.294	5	2	9
17	R:R:Y120	8.54	4	0	8
18	R:R:Q133	13.23	4	2	7
19	R:R:W146	6.8825	4	2	9
20	R:R:Y189	4.8425	4	0	4
21	R:R:F191	10.29	4	0	5
22	R:R:F195	13.836	5	1	9
23	R:R:W196	5.765	4	0	4
24	R:R:F205	9.615	4	0	8
25	R:R:Y206	6.24667	6	2	9
26	R:R:H217	3.7875	4	0	4
27	R:R:S224	2.61	4	0	4
28	R:R:F242	6.9675	4	1	9
29	R:R:F246	8.23667	6	1	9
30	R:R:Y249	10.538	5	1	7
31	R:R:H250	15.6175	4	1	8
32	R:R:R253	10.916	5	1	6
33	R:R:Y256	10.795	4	1	5
34	R:R:Y265	7.61	4	6	1
35	R:R:R274	8.835	4	1	3
36	R:R:Y275	8.044	5	1	2
37	R:R:K277	9.3	4	1	5
38	R:R:N287	8.3025	4	0	9
39	R:R:V288	5.4	4	3	8
40	R:R:I294	3.345	4	5	8
41	R:R:F296	7.24286	7	2	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:Y256	24.3045	4.74	Yes	Yes	1	0	5
2	R:R:R274	R:R:Y256	28.4038	7.2	Yes	Yes	1	3	5
3	R:R:R274	R:R:Y275	17.1293	7.2	Yes	Yes	1	3	2
4	L:L:?1	R:R:Y102	50.1946	24.28	Yes	Yes	1	0	5
5	R:R:F101	R:R:Y102	34.2097	5.16	Yes	Yes	1	7	5
6	R:R:F101	R:R:F74	28.5134	6.43	Yes	Yes	0	7	8
7	R:R:A285	R:R:F74	38.309	4.16	No	Yes	0	7	8
8	R:R:A285	R:R:Y29	36.8647	5.34	No	Yes	0	7	8
9	R:R:I25	R:R:Y29	17.6771	2.42	No	Yes	0	6	8
10	R:R:I25	R:R:P26	11.0496	3.39	No	No	0	6	5
11	R:R:K77	R:R:Y29	12.8427	21.5	No	Yes	0	7	8
12	R:R:F33	R:R:F74	19.2655	5.36	No	Yes	0	7	8
13	R:R:F33	R:R:I37	16.1117	11.3	No	Yes	0	7	7
14	R:R:F101	R:R:M70	17.2764	9.95	Yes	Yes	0	7	7
15	R:R:M70	R:R:V288	28.7526	6.09	Yes	Yes	0	7	8
16	R:R:N40	R:R:V288	23.679	4.43	No	Yes	3	9	8
17	R:R:N40	R:R:P292	23.2437	4.89	No	No	0	9	9
18	R:R:F74	R:R:V288	51.7599	5.24	Yes	Yes	0	8	8
19	R:R:D67	R:R:V288	53.0312	5.84	Yes	Yes	3	9	8
20	R:R:F296	R:R:P292	22.2117	5.78	Yes	No	0	7	9
21	R:R:D67	R:R:I63	36.7984	4.2	Yes	No	0	9	9
22	R:R:F296	R:R:I63	30.8369	5.02	Yes	No	0	7	9
23	R:R:F296	R:R:F302	14.777	6.43	Yes	No	2	7	9
24	R:R:F302	R:R:I46	15.6073	10.05	No	Yes	0	9	7
25	R:R:F296	R:R:L60	30.2113	8.53	Yes	Yes	2	7	8
26	R:R:Y102	R:R:Y249	28.1674	6.95	Yes	Yes	1	5	7
27	R:R:H250	R:R:Y249	69.7397	13.07	Yes	Yes	1	8	7
28	R:R:F195	R:R:H250	49.3384	35.07	Yes	Yes	1	9	8
29	R:R:F195	R:R:F242	42.2295	5.36	Yes	Yes	1	9	9
30	R:R:F112	R:R:F242	82.6516	5.36	Yes	Yes	0	9	9
31	R:R:F112	R:R:Y295	100	13.41	Yes	No	0	9	9
32	R:R:R119	R:R:Y295	99.04	8.23	Yes	No	0	9	9
33	R:R:I115	R:R:R119	62.0831	7.52	No	Yes	2	9	9
34	R:R:I115	R:R:Y59	81.2996	4.84	No	Yes	2	9	7
35	L:L:?1	R:R:R253	27.6658	9.21	Yes	Yes	1	0	6
36	R:R:R253	R:R:Y249	47.2426	13.38	Yes	Yes	1	6	7
37	L:L:?1	R:R:F191	24.7802	4.92	Yes	Yes	0	0	5
38	R:R:F191	R:R:Y106	29.6549	23.73	Yes	No	0	5	8
39	R:R:H250	R:R:Y106	30.1306	9.8	Yes	No	0	8	8
40	R:R:F246	R:R:H250	50.1831	4.53	Yes	Yes	1	9	8
41	R:R:F242	R:R:F246	40.9409	9.65	Yes	Yes	1	9	9
42	R:R:F56	R:R:L60	25.5211	12.18	No	Yes	2	8	8
43	R:R:F111	R:R:Y59	18.5477	5.16	No	Yes	2	8	7
44	R:R:F111	R:R:W146	10.3174	5.01	No	Yes	2	8	9
45	R:R:D291	R:R:D67	18.0172	7.98	No	Yes	0	9	9
46	R:R:M70	R:R:N104	22.6383	5.61	Yes	No	0	7	8
47	R:R:N104	R:R:V69	19.473	10.35	No	No	0	8	7
48	R:R:L100	R:R:V69	17.8818	4.47	No	No	0	5	7
49	R:R:L100	R:R:T73	16.2847	4.42	No	No	0	5	7
50	R:R:S97	R:R:T73	14.6819	3.2	No	No	0	5	7
51	R:R:D81	R:R:K77	11.2572	12.44	No	No	0	5	7
52	R:R:R119	R:R:Y206	39.71	8.23	Yes	Yes	2	9	9
53	R:R:Q133	R:R:Y59	43.054	18.04	Yes	Yes	2	7	7
54	R:R:F117	R:R:Q133	38.1072	16.4	Yes	Yes	0	6	7
55	R:R:F117	R:R:F205	19.5682	10.72	Yes	Yes	0	6	8
56	R:R:F205	R:R:Y120	11.8193	16.5	Yes	Yes	0	8	8
57	R:R:F117	R:R:W128	15.9762	7.02	Yes	No	0	6	4
58	R:R:W128	R:R:Y121	10.326	13.5	No	No	4	4	6
59	L:L:?1	R:R:N156	26.8961	13.18	Yes	No	0	0	5
60	R:R:N156	R:R:S187	24.7024	5.96	No	No	0	5	4
61	R:R:S187	R:R:W183	22.2578	6.18	No	No	0	4	2
62	R:R:P155	R:R:W183	19.8074	12.16	No	No	0	7	2
63	R:R:L159	R:R:P155	12.4218	3.28	No	No	0	5	7
64	L:L:?1	R:R:Q260	14.1832	8.74	Yes	No	1	0	3
65	R:R:I173	R:R:Q260	12.3353	5.49	No	No	0	4	3
66	R:R:T257	R:R:Y189	26.7924	3.75	No	Yes	0	5	4
67	R:R:R253	R:R:T257	23.2062	7.76	Yes	No	1	6	5
68	R:R:I109	R:R:V198	11.9606	3.07	No	No	1	8	9
69	R:R:I235	R:R:Y206	32.7078	6.04	No	Yes	0	8	9
70	R:R:I235	R:R:T210	31.0905	6.08	No	No	0	8	5
71	R:R:F236	R:R:T210	29.4791	3.89	No	No	0	5	5
72	R:R:F236	R:R:S232	27.8993	3.96	No	No	0	5	6
73	R:R:S231	R:R:S232	25.0944	1.63	No	No	0	8	6
74	R:R:I213	R:R:S231	23.8923	4.64	No	No	0	8	8
75	R:R:I213	R:R:S216	22.2232	1.55	No	No	0	8	5
76	R:R:H217	R:R:S216	18.8619	4.18	Yes	No	0	4	5
77	R:R:H217	R:R:S224	12.1047	5.58	Yes	Yes	0	4	4
78	R:R:K258	R:R:Y189	13.474	3.58	No	Yes	0	3	4
79	R:R:C299	R:R:L60	10.8103	3.17	No	Yes	0	8	8
80	R:R:F112	R:R:I63	22.9727	8.79	Yes	No	0	9	9
81	R:R:F56	R:R:I115	21.0067	7.54	No	No	2	8	9
82	R:R:D291	R:R:F112	15.8782	10.75	No	Yes	0	9	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?1	R:R:C94	8.02	1	Yes	No	0	9	0	1
L:L:?1	R:R:V99	5.27	1	Yes	No	0	6	0	1
L:L:?1	R:R:Y102	24.28	1	Yes	Yes	0	5	0	1
L:L:?1	R:R:N156	13.18	1	Yes	No	0	5	0	1
L:L:?1	R:R:K176	5.7	1	Yes	No	0	4	0	1
L:L:?1	R:R:H184	14.94	1	Yes	No	0	3	0	1
L:L:?1	R:R:N188	6.24	1	Yes	No	0	4	0	1
L:L:?1	R:R:F191	4.92	1	Yes	Yes	0	5	0	1
L:L:?1	R:R:R253	9.21	1	Yes	Yes	0	6	0	1
L:L:?1	R:R:Y256	4.74	1	Yes	Yes	0	5	0	1
L:L:?1	R:R:Q260	8.74	1	Yes	No	0	3	0	1
L:L:?1	R:R:K277	7.12	1	Yes	Yes	0	5	0	1
L:L:?1	R:R:E278	8.03	1	Yes	No	0	5	0	1
R:R:C172	R:R:C94	7.28	0	No	No	9	9	2	1
R:R:I157	R:R:V99	7.68	0	No	No	5	6	2	1
R:R:F101	R:R:Y102	5.16	1	Yes	Yes	7	5	2	1
R:R:F101	R:R:L281	7.31	1	Yes	No	7	6	2	2
R:R:Y102	R:R:Y249	6.95	1	Yes	Yes	5	7	1	2
R:R:L281	R:R:Y102	8.21	1	No	Yes	6	5	2	1
R:R:F191	R:R:Y106	23.73	0	Yes	No	5	8	1	2
R:R:F191	R:R:L152	9.74	0	Yes	No	5	5	1	2
R:R:N156	R:R:S187	5.96	0	No	No	5	4	1	2
R:R:K176	R:R:T160	6.01	1	No	No	4	5	1	2
R:R:I173	R:R:Q260	5.49	0	No	No	4	3	2	1
R:R:H184	R:R:K176	5.24	1	No	No	3	4	1	1
R:R:N188	R:R:R253	19.28	1	No	Yes	4	6	1	1
R:R:N188	R:R:T257	13.16	1	No	No	4	5	1	2
R:R:R253	R:R:Y249	13.38	1	Yes	Yes	6	7	1	2
R:R:L281	R:R:Y249	10.55	1	No	Yes	6	7	2	2
R:R:R253	R:R:T257	7.76	1	Yes	No	6	5	1	2
R:R:K277	R:R:R253	4.95	1	Yes	Yes	5	6	1	1
R:R:Q260	R:R:Y256	16.91	1	No	Yes	3	5	1	1
R:R:R274	R:R:Y256	7.2	1	Yes	Yes	3	5	2	1
R:R:K277	R:R:Y256	14.33	1	Yes	Yes	5	5	1	1
R:R:E278	R:R:K277	10.8	1	No	Yes	5	5	1	1
L:L:?1	R:R:A98	3.18	1	Yes	No	0	6	0	1
R:R:A153	R:R:F191	2.77	0	No	Yes	7	5	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	9J0B_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	4.14
Number of Linked Nodes	280
Number of Links	313
Number of Hubs	41
Number of Links mediated by Hubs	157
Number of Communities	6
Number of Nodes involved in Communities	55
Number of Links involved in Communities	76

Path Summary
Number Of Nodes in MetaPath	83
Number Of Links MetaPath	82
Number of Shortest Paths	86709
Length Of Smallest Path	3
Average Path Length	13.7185
Length of Longest Path	30
Minimum Path Strength	1.22
Average Path Strength	8.12004
Maximum Path Strength	24.07
Minimum Path Correlation	0.7
Average Path Correlation	0.921728
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	4.54545
Average % Of Corr. Nodes	46.511
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	51.1827
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain • Ras-like P-loop GTPases
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain • Ras-like P-loop GTPases
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	UPG
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	UPG
Name	Uridine diphosphate glucose
Synonyms	Uridine diphosphate glucose
Identifier
Formula	C15 H24 N2 O17 P2
Molecular Weight	566.302
SMILES
PubChem	8629
Formal Charge	0
Total Atoms	60
Total Chiral Atoms	9
Total Bonds	62
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q15391
Sequence	>9J0B_nogp_Chain_R Q N L L I T Q Q I I P V L Y C M V F I A G I L L N G V S G W I F F Y V P S S K S F I I Y L K N I V I A D F V M S L T F P F K I L G D S G L G P W Q L N V F V C R V S A V L F Y V N M Y V S I V F F G L I S F D R Y Y K I V K P L W T S F I Q S V S Y S K L L S V I V W M L M L L L A V P N I I L T N Q S V R E V T Q I K C I E L K S E L G R K W H K A S N Y I F V A I F W I V F L L L I V F Y T A I T K K I F K S H L K S S R N S T S V K K K S S R N I F S I V F V F F V C F V P Y H I A R I P Y T K S Q T E A H Y S C Q S K E I L R Y M K E F T L L L S A A N V C L D P I I Y F F L C Q P F R E I L C K K L Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	9J0F	A	Nucleotide	P2Y	P2Y₁₄	Homo sapiens	NADH	-	Gi1/β1/γ2	2.76	2025-06-04	doi.org/10.1038/s41421-025-00799-9
	9J0F (No Gprot)	A	Nucleotide	P2Y	P2Y₁₄	Homo sapiens	NADH	-		2.76	2025-06-04	doi.org/10.1038/s41421-025-00799-9
	9J0I	A	Nucleotide	P2Y	P2Y₁₄	Homo sapiens	UDP-Glucuronic acid	-	Gi1/β1/γ2	2.76	2025-06-04	doi.org/10.1038/s41421-025-00799-9
	9J0I (No Gprot)	A	Nucleotide	P2Y	P2Y₁₄	Homo sapiens	UDP-Glucuronic acid	-		2.76	2025-06-04	doi.org/10.1038/s41421-025-00799-9
	9J0B	A	Nucleotide	P2Y	P2Y₁₄	Homo sapiens	UDP-Glucose	-	Gi1/β1/γ2	2.88	2025-06-04	10.1038/s41421-025-00799-9
	9J0B (No Gprot)	A	Nucleotide	P2Y	P2Y₁₄	Homo sapiens	UDP-Glucose	-		2.88	2025-06-04	10.1038/s41421-025-00799-9
	9J05	A	Nucleotide	P2Y	P2Y₁₄	Homo sapiens	-	-	-	3.2	2025-08-06	To be published
	9YDU	A	Nucleotide	P2Y	P2Y₁₄	Homo sapiens	UDP-Glucose	-	Gi1/β1/γ2	3.19	2025-11-19	10.1038/s42003-025-09174-6
	9YDU (No Gprot)	A	Nucleotide	P2Y	P2Y₁₄	Homo sapiens	UDP-Glucose	-		3.19	2025-11-19	10.1038/s42003-025-09174-6
	9YDV	A	Nucleotide	P2Y	P2Y₁₄	Homo sapiens	MRS2905	-	Gi1/β1/γ2	3.05	2025-11-19	10.1038/s42003-025-09174-6
	9YDV (No Gprot)	A	Nucleotide	P2Y	P2Y₁₄	Homo sapiens	MRS2905	-		3.05	2025-11-19	10.1038/s42003-025-09174-6

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