psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:L61	L:L:T1	4.42	Yes	No	0	0	0
2	L:L:I6	L:L:L2	4.28	Yes	No	0	0	0
3	L:L:L2	L:L:L61	16.61	No	Yes	0	0	0
4	L:L:K4	L:L:Q3	4.07	No	No	0	0	0
5	L:L:E7	L:L:Q3	3.82	No	No	0	0	0
6	L:L:Q3	R:R:Y181	10.15	No	No	0	0	1
7	L:L:I9	L:L:K5	5.82	No	No	0	0	0
8	L:L:A26	L:L:I6	3.25	No	Yes	2	0	0
9	L:L:I6	R:R:F182	10.05	Yes	Yes	2	0	3
10	L:L:E8	L:L:I9	5.47	No	No	0	0	0
11	L:L:I9	L:L:V57	4.61	No	No	0	0	0
12	L:L:A10	L:L:K19	3.21	No	No	0	0	0
13	L:L:A10	L:L:C22	3.61	No	No	0	0	0
14	L:L:K12	L:L:Y13	4.78	No	Yes	0	0	0
15	L:L:V18	L:L:Y13	12.62	No	Yes	0	0	0
16	L:L:A50	L:L:Y13	6.67	No	Yes	0	0	0
17	L:L:H15	L:L:V17	5.54	No	No	0	0	0
18	L:L:R46	L:L:V18	3.92	No	No	0	0	0
19	L:L:K20	R:R:L22	4.23	No	No	0	0	3
20	L:L:K20	R:R:T24	4.5	No	No	0	0	4
21	L:L:C21	L:L:C47	7.28	No	No	0	0	0
22	L:L:C22	L:L:C54	7.28	No	No	0	0	0
23	L:L:Y23	R:R:F182	12.38	No	Yes	0	0	3
24	L:L:D24	R:R:D27	14.64	No	No	0	0	9
25	L:L:G25	R:R:D27	3.35	No	No	0	0	9
26	L:L:A26	R:R:F182	4.16	No	Yes	2	0	3
27	L:L:C27	L:L:N29	6.3	No	No	0	0	0
28	L:L:N29	R:R:K28	9.79	No	Yes	4	0	3
29	L:L:N29	R:R:T29	4.39	No	Yes	4	0	5
30	L:L:N30	R:R:L276	9.61	No	No	0	0	3
31	L:L:D31	L:L:R37	5.96	No	Yes	4	0	0
32	L:L:D31	R:R:K28	16.59	No	Yes	4	0	3
33	L:L:D31	R:R:T29	8.67	No	Yes	4	0	5
34	L:L:C34	L:L:C55	7.28	No	No	0	0	0
35	L:L:C34	R:R:K28	4.85	No	Yes	0	0	3
36	L:L:R37	L:L:R40	18.13	Yes	No	0	0	0
37	L:L:R37	R:R:K28	8.66	Yes	Yes	4	0	3
38	L:L:R37	R:R:T29	5.17	Yes	Yes	4	0	5
39	L:L:A38	L:L:I41	3.25	No	No	0	0	0
40	L:L:I41	L:L:L43	7.14	No	No	0	0	0
41	L:L:F51	L:L:I41	8.79	No	No	0	0	0
42	L:L:C47	L:L:L43	11.11	No	No	0	0	0
43	L:L:G44	L:L:P45	4.06	No	No	0	0	0
44	L:L:L61	L:L:N64	5.49	Yes	No	0	0	0
45	L:L:H67	R:R:V176	4.15	Yes	No	5	0	4
46	L:L:H67	R:R:R178	14.67	Yes	No	0	0	2
47	L:L:H67	R:R:G189	3.18	Yes	No	0	0	4
48	L:L:H67	R:R:D191	11.35	Yes	No	5	0	4
49	L:L:K68	R:R:Y192	3.58	No	Yes	0	0	5
50	L:L:D69	R:R:H100	16.39	No	No	0	0	4
51	L:L:D69	R:R:L187	4.07	No	No	0	0	4
52	L:L:M70	R:R:R175	3.72	No	Yes	0	0	5
53	L:L:Q71	R:R:S95	4.33	No	No	0	0	4
54	L:L:Q71	R:R:I96	8.23	No	No	0	0	5
55	L:L:Q71	R:R:H100	4.95	No	No	0	0	4
56	L:L:L72	R:R:L92	6.92	Yes	No	0	0	6
57	L:L:L72	R:R:S95	4.5	Yes	No	0	0	4
58	L:L:L72	R:R:W102	3.42	Yes	Yes	0	0	8
59	L:L:L72	R:R:P113	3.28	Yes	No	0	0	6
60	L:L:R74	R:R:Y258	12.35	Yes	Yes	1	0	7
61	L:L:R74	R:R:T261	3.88	Yes	Yes	1	0	4
62	L:L:R74	R:R:D282	17.87	Yes	No	1	0	4
63	L:L:R74	R:R:V286	5.23	Yes	No	1	0	5
64	R:R:P25	R:R:S30	7.13	No	No	0	8	4
65	R:R:K28	R:R:T29	9.01	Yes	Yes	4	3	5
66	R:R:R34	R:R:T32	6.47	No	No	0	2	4
67	R:R:P36	R:R:V35	3.53	No	Yes	0	3	3
68	R:R:D37	R:R:V35	5.84	No	Yes	0	4	3
69	R:R:L284	R:R:P36	4.93	No	No	0	4	3
70	R:R:D37	R:R:S283	7.36	No	No	0	4	4
71	R:R:L284	R:R:L39	4.15	No	No	0	4	5
72	R:R:A40	R:R:S283	3.42	No	No	0	6	4
73	R:R:A40	R:R:L284	4.73	No	No	0	6	4
74	R:R:A40	R:R:S287	3.42	No	No	0	6	4
75	R:R:F93	R:R:L41	15.83	No	No	0	7	5
76	R:R:I43	R:R:S287	9.29	No	No	0	5	4
77	R:R:F44	R:R:L89	3.65	Yes	Yes	1	7	7
78	R:R:F44	R:R:L92	3.65	Yes	No	1	7	6
79	R:R:F44	R:R:V286	3.93	Yes	No	1	7	5
80	R:R:F44	R:R:S287	7.93	Yes	No	0	7	4
81	R:R:F44	R:R:Y290	8.25	Yes	Yes	1	7	7
82	R:R:V47	R:R:Y290	6.31	No	Yes	0	6	7
83	R:R:C294	R:R:V47	5.12	No	No	0	7	6
84	R:R:F48	R:R:V52	7.87	Yes	No	0	6	5
85	R:R:F48	R:R:L89	8.53	Yes	Yes	0	6	7
86	R:R:C294	R:R:V50	6.83	No	No	0	7	6
87	R:R:G51	R:R:N55	3.39	No	No	0	8	9
88	R:R:C86	R:R:G51	3.92	No	No	0	5	8
89	R:R:D82	R:R:N55	6.73	Yes	No	0	9	9
90	R:R:N55	R:R:P297	16.29	No	No	0	9	9
91	R:R:A56	R:R:W60	5.19	No	Yes	0	3	4
92	R:R:L57	R:R:W60	5.69	No	Yes	0	5	4
93	R:R:T62	R:R:V58	3.17	Yes	Yes	0	6	8
94	R:R:A79	R:R:V58	3.39	No	Yes	0	8	8
95	R:R:V59	R:R:W60	3.68	No	Yes	0	7	4
96	R:R:F64	R:R:W60	6.01	No	Yes	0	4	4
97	R:R:T62	R:R:V61	4.76	Yes	No	0	6	6
98	R:R:A72	R:R:T62	3.36	No	Yes	0	7	6
99	R:R:L76	R:R:T62	4.42	No	Yes	0	6	6
100	R:R:E65	R:R:R310	4.65	No	No	0	5	4
101	R:R:K67	R:R:L76	4.23	No	No	0	6	6
102	R:R:R68	R:R:T69	5.17	No	No	0	7	7
103	R:R:I70	R:R:R148	7.52	No	No	0	6	7
104	R:R:G149	R:R:I70	3.53	No	No	0	5	6
105	R:R:L137	R:R:N71	4.12	Yes	No	6	8	7
106	R:R:N71	R:R:R148	6.03	No	No	6	7	7
107	R:R:A153	R:R:I73	6.5	No	No	0	7	6
108	R:R:I73	R:R:W154	14.09	No	No	0	6	3
109	R:R:T129	R:R:W74	7.28	No	Yes	0	6	7
110	R:R:I130	R:R:W74	3.52	No	Yes	0	8	7
111	R:R:D133	R:R:W74	22.33	No	Yes	0	8	7
112	R:R:A153	R:R:W74	3.89	No	Yes	0	7	7
113	R:R:F75	R:R:R134	3.21	No	Yes	3	8	9
114	R:R:F75	R:R:Y300	12.38	No	Yes	3	8	9
115	R:R:N77	R:R:W154	5.65	No	No	0	9	3
116	R:R:C157	R:R:N77	11.02	No	No	0	6	9
117	R:R:N77	R:R:W161	4.52	No	Yes	0	9	9
118	R:R:L126	R:R:L78	15.22	No	Yes	0	7	9
119	R:R:L127	R:R:L78	4.15	No	Yes	3	8	9
120	R:R:I130	R:R:L78	8.56	No	Yes	0	8	9
121	R:R:L78	R:R:N296	4.12	Yes	Yes	3	9	9
122	R:R:D82	R:R:S123	8.83	Yes	No	0	9	9
123	R:R:C293	R:R:D82	6.22	No	Yes	0	8	9
124	R:R:D82	R:R:N296	9.42	Yes	Yes	0	9	9
125	R:R:F83	R:R:L84	3.65	No	No	0	8	6
126	R:R:F83	R:R:L87	12.18	No	No	0	8	4
127	R:R:L84	R:R:N119	9.61	No	No	0	6	9
128	R:R:N119	R:R:S85	4.47	No	No	0	9	6
129	R:R:M120	R:R:S85	4.6	Yes	No	0	7	6
130	R:R:C86	R:R:L89	4.76	No	Yes	0	5	7
131	R:R:A88	R:R:I116	4.87	No	No	0	6	6
132	R:R:L89	R:R:Y290	14.07	Yes	Yes	1	7	7
133	R:R:I91	R:R:L112	8.56	No	Yes	0	6	5
134	R:R:L92	R:R:Y290	3.52	No	Yes	1	6	7
135	R:R:F93	R:R:V97	5.24	No	No	0	7	3
136	R:R:Q98	R:R:V97	4.3	No	No	0	4	3
137	R:R:H101	R:R:P103	7.63	No	No	0	4	3
138	R:R:H101	R:R:V186	5.54	No	No	0	4	6
139	R:R:F104	R:R:W102	16.04	No	Yes	0	7	8
140	R:R:L112	R:R:W102	5.69	Yes	Yes	0	5	8
141	R:R:C188	R:R:W102	7.84	No	Yes	0	9	8
142	R:R:F104	R:R:P103	5.78	No	No	0	7	3
143	R:R:A108	R:R:F104	4.16	No	No	0	5	7
144	R:R:C109	R:R:V177	3.42	No	No	0	9	4
145	R:R:C109	R:R:C188	7.28	No	No	0	9	9
146	R:R:L112	R:R:P113	4.93	Yes	No	0	5	6
147	R:R:I116	R:R:L112	5.71	No	Yes	0	6	5
148	R:R:P113	R:R:R175	4.32	No	Yes	0	6	5
149	R:R:L115	R:R:S114	4.5	No	No	0	5	5
150	R:R:S114	R:R:T168	3.2	No	No	0	5	6
151	R:R:F172	R:R:S114	5.28	No	No	0	4	5
152	R:R:L115	R:R:L118	4.15	No	Yes	0	5	5
153	R:R:L117	R:R:Y121	4.69	No	No	0	4	7
154	R:R:L118	R:R:W161	3.42	Yes	Yes	0	5	9
155	R:R:A164	R:R:L118	3.15	No	Yes	0	7	5
156	R:R:L118	R:R:L165	8.3	Yes	No	0	5	4
157	R:R:M120	R:R:W255	3.49	Yes	Yes	1	7	9
158	R:R:M120	R:R:Y258	3.59	Yes	Yes	1	7	7
159	R:R:M120	R:R:Y290	5.99	Yes	Yes	1	7	7
160	R:R:L167	R:R:Y121	4.69	No	No	0	4	7
161	R:R:R206	R:R:Y121	10.29	No	No	0	6	7
162	R:R:A122	R:R:W161	7.78	No	Yes	0	6	9
163	R:R:I124	R:R:P214	3.39	No	No	0	8	9
164	R:R:I124	R:R:W255	12.92	No	Yes	0	8	9
165	R:R:L125	R:R:L163	4.15	No	No	0	6	4
166	R:R:L125	R:R:W213	3.42	No	No	0	6	5
167	R:R:C157	R:R:L126	3.17	No	No	0	6	7
168	R:R:A160	R:R:L126	3.15	No	No	0	6	7
169	R:R:L127	R:R:N292	4.12	No	No	0	8	9
170	R:R:L127	R:R:N296	12.36	No	Yes	3	8	9
171	R:R:A128	R:R:T217	3.36	No	No	0	7	5
172	R:R:I130	R:R:R134	6.26	No	Yes	0	8	9
173	R:R:S131	R:R:T217	3.2	No	No	0	9	5
174	R:R:C221	R:R:S131	3.44	No	No	0	6	9
175	R:R:S131	R:R:Y222	12.72	No	Yes	0	9	8
176	R:R:D133	R:R:L137	6.79	No	Yes	0	8	8
177	R:R:R134	R:R:Y222	9.26	Yes	Yes	0	9	8
178	R:R:R134	R:R:Y300	10.29	Yes	Yes	3	9	9
179	R:R:F135	R:R:F139	17.15	No	No	7	8	7
180	R:R:C221	R:R:F135	8.38	No	No	0	6	8
181	R:R:F135	R:R:F224	5.36	No	No	7	8	3
182	R:R:C144	R:R:L137	4.76	No	Yes	0	5	8
183	R:R:L137	R:R:R148	8.5	Yes	No	6	8	7
184	R:R:F139	R:R:F224	5.36	No	No	7	7	3
185	R:R:F139	R:R:R228	17.1	No	No	0	7	5
186	R:R:K140	R:R:W143	38.29	No	No	0	6	5
187	R:R:I142	R:R:W143	8.22	No	No	0	5	5
188	R:R:F147	R:R:W143	6.01	No	No	0	4	5
189	R:R:F147	R:R:N146	4.83	No	No	0	4	5
190	R:R:L167	R:R:L209	5.54	No	No	0	4	4
191	R:R:I169	R:R:P170	3.39	No	No	0	3	8
192	R:R:P170	R:R:V202	7.07	No	No	0	8	5
193	R:R:P170	R:R:R206	4.32	No	No	0	8	6
194	R:R:R175	R:R:S171	9.22	Yes	No	0	5	5
195	R:R:L173	R:R:Y174	4.69	No	No	0	4	4
196	R:R:R198	R:R:Y174	8.23	No	No	0	3	4
197	R:R:C188	R:R:R175	5.57	No	Yes	0	9	5
198	R:R:R175	R:R:V190	6.54	Yes	No	0	5	5
199	R:R:D191	R:R:V176	13.15	No	No	5	4	4
200	R:R:L187	R:R:R178	10.93	No	No	0	4	2
201	R:R:E179	R:R:Y181	6.73	No	No	0	2	1
202	R:R:E179	R:R:V186	7.13	No	No	0	2	6
203	R:R:E180	R:R:F182	7	No	Yes	2	1	3
204	R:R:E180	R:R:P183	9.43	No	Yes	2	1	4
205	R:R:E180	R:R:K185	6.75	No	No	2	1	3
206	R:R:F182	R:R:P183	4.33	Yes	Yes	2	3	4
207	R:R:K185	R:R:P183	5.02	No	Yes	2	3	4
208	R:R:V190	R:R:Y192	17.66	No	Yes	0	5	5
209	R:R:D191	R:R:H194	8.82	No	No	0	4	1
210	R:R:E199	R:R:Y192	10.1	No	Yes	0	4	5
211	R:R:K196	R:R:S193	12.24	No	No	0	2	4
212	R:R:R197	R:R:R200	7.46	No	No	0	1	3
213	R:R:E199	R:R:R200	3.49	No	No	0	4	3
214	R:R:F267	R:R:R200	11.76	No	No	0	4	3
215	R:R:A203	R:R:S266	3.42	No	No	0	5	5
216	R:R:F267	R:R:I204	5.02	No	No	0	4	3
217	R:R:L207	R:R:L212	4.15	No	No	0	5	4
218	R:R:L207	R:R:Q259	6.65	No	No	0	5	8
219	R:R:I263	R:R:L207	4.28	No	No	0	5	5
220	R:R:F211	R:R:L212	4.87	Yes	No	0	8	4
221	R:R:F211	R:R:L215	3.65	Yes	No	1	8	5
222	R:R:F211	R:R:F251	4.29	Yes	Yes	1	8	9
223	R:R:F211	R:R:W255	4.01	Yes	Yes	1	8	9
224	R:R:F211	R:R:L256	3.65	Yes	No	0	8	5
225	R:R:F211	R:R:Q259	15.23	Yes	No	0	8	8
226	R:R:P214	R:R:W213	6.76	No	No	0	9	5
227	R:R:T217	R:R:W213	7.28	No	No	0	5	5
228	R:R:F251	R:R:L215	3.65	Yes	No	1	9	5
229	R:R:F252	R:R:L215	6.09	No	No	0	5	5
230	R:R:F251	R:R:L218	8.53	Yes	No	0	9	8
231	R:R:T219	R:R:V248	3.17	No	No	0	4	7
232	R:R:V244	R:R:Y222	12.62	No	Yes	0	7	8
233	R:R:V247	R:R:Y222	8.83	No	Yes	0	7	8
234	R:R:I225	R:R:T229	4.56	No	Yes	0	8	8
235	R:R:L226	R:R:L241	5.54	No	No	0	5	6
236	R:R:L226	R:R:V244	7.45	No	No	0	5	7
237	R:R:T229	R:R:W230	3.64	Yes	No	0	8	4
238	R:R:T229	R:R:T240	7.85	Yes	No	0	8	7
239	R:R:R236	R:R:W230	6	No	No	0	5	4
240	R:R:L241	R:R:W230	9.11	No	No	0	6	4
241	R:R:K239	R:R:Q305	10.85	Yes	No	0	7	6
242	R:R:A246	R:R:I299	3.25	No	No	0	5	7
243	R:R:F251	R:R:W255	7.02	Yes	Yes	1	9	9
244	R:R:F252	R:R:L256	6.09	No	No	0	5	5
245	R:R:F254	R:R:I253	3.77	Yes	No	0	8	5
246	R:R:F254	R:R:F288	7.5	Yes	No	0	8	8
247	R:R:F254	R:R:I291	27.63	Yes	No	8	8	5
248	R:R:F254	R:R:I295	3.77	Yes	No	8	8	7
249	R:R:W255	R:R:Y258	5.79	Yes	Yes	1	9	7
250	R:R:A289	R:R:W255	5.19	No	Yes	1	8	9
251	R:R:N292	R:R:W255	13.56	No	Yes	0	9	9
252	R:R:L256	R:R:P257	3.28	No	No	0	5	9
253	R:R:F288	R:R:P257	4.33	No	No	0	8	9
254	R:R:Q259	R:R:Y258	6.76	No	Yes	0	8	7
255	R:R:V286	R:R:Y258	6.31	No	Yes	1	5	7
256	R:R:A289	R:R:Y258	4	No	Yes	1	8	7
257	R:R:D282	R:R:T261	4.34	No	Yes	1	4	4
258	R:R:C285	R:R:T261	6.76	No	Yes	0	6	4
259	R:R:L278	R:R:M264	8.48	No	No	0	4	4
260	R:R:F275	R:R:M265	4.98	No	No	0	3	4
261	R:R:L278	R:R:M265	5.65	No	No	0	4	4
262	R:R:D282	R:R:M265	9.7	No	No	0	4	4
263	R:R:E269	R:R:L268	7.95	No	No	0	3	2
264	R:R:L268	R:R:T274	11.79	No	No	0	2	1
265	R:R:F275	R:R:L268	13.4	No	No	0	3	2
266	R:R:E269	R:R:S272	7.19	No	No	0	3	4
267	R:R:P273	R:R:S272	3.56	No	No	0	2	4
268	R:R:S272	R:R:T274	4.8	No	No	0	4	1
269	R:R:F275	R:R:K279	11.17	No	No	0	3	4
270	R:R:K280	R:R:L276	8.46	No	No	0	2	3
271	R:R:K280	R:R:L277	5.64	No	No	0	2	1
272	R:R:I291	R:R:I295	4.42	No	No	8	5	7
273	R:R:N296	R:R:Y300	4.65	Yes	Yes	3	9	9
274	R:R:I299	R:R:Y300	12.09	No	Yes	0	7	9
275	R:R:Q305	R:R:Q308	12.8	No	No	0	6	8
276	R:R:F307	R:R:R310	11.76	No	No	0	9	4
277	R:R:T229	R:R:T235	3.14	Yes	No	0	8	4
278	R:R:E269	R:R:P270	3.14	No	No	0	3	3
279	R:R:I298	R:R:V50	3.07	No	No	0	7	6
280	R:R:I225	R:R:V138	3.07	No	No	0	8	8
281	R:R:I299	R:R:V243	3.07	No	No	0	7	7
282	L:L:F51	L:L:G25	3.01	No	No	0	0	0
283	L:L:G73	L:L:R74	3	No	Yes	0	0	0
284	L:L:R74	R:R:G262	3	Yes	No	0	0	5
285	R:R:L76	R:R:V59	2.98	No	No	0	6	7
286	R:R:L163	R:R:V159	2.98	No	No	0	4	1
287	R:R:Y174	R:R:Y192	2.98	No	Yes	0	4	5
288	R:R:L209	R:R:V208	2.98	No	No	0	4	4
289	R:R:L241	R:R:V245	2.98	No	No	0	6	4
290	R:R:L227	R:R:T223	2.95	No	No	0	4	2
291	L:L:S66	R:R:D195	2.94	No	No	0	0	3
292	R:R:F48	R:R:P90	2.89	Yes	No	0	6	9
293	R:R:K239	R:R:K242	2.87	Yes	No	0	7	6
294	L:L:I65	L:L:L61	2.85	No	Yes	0	0	0
295	R:R:I169	R:R:L173	2.85	No	No	0	3	4
296	L:L:Q36	L:L:T33	2.83	No	No	0	0	0
297	L:L:E53	L:L:T52	2.82	No	No	0	0	0
298	R:R:K140	R:R:L136	2.82	No	No	0	6	5
299	L:L:C34	L:L:F51	2.79	No	No	0	0	0
300	R:R:L311	R:R:L57	2.77	No	No	0	6	5
301	R:R:A63	R:R:F64	2.77	No	No	0	3	4
302	L:L:H67	L:L:I65	2.65	Yes	No	0	0	0
303	R:R:R175	R:R:S110	2.64	Yes	No	0	5	6
304	R:R:F254	R:R:S250	2.64	Yes	No	0	8	6
305	L:L:R62	L:L:V28	2.62	No	No	0	0	0
306	R:R:F307	R:R:V61	2.62	No	No	0	9	6
307	R:R:A156	R:R:W74	2.59	No	Yes	0	5	7
308	R:R:A81	R:R:W161	2.59	No	Yes	0	8	9
309	R:R:A150	R:R:W154	2.59	No	No	0	3	3
310	R:R:H99	R:R:L33	2.57	No	No	0	2	4
311	R:R:V248	R:R:Y222	2.52	No	Yes	0	7	8
312	R:R:F224	R:R:I220	2.51	No	No	0	3	3
313	L:L:K19	L:L:Y23	2.39	No	No	0	0	0
314	R:R:G105	R:R:G106	2.11	No	No	0	7	3
315	R:R:G54	R:R:P297	2.03	No	No	0	7	9
316	R:R:G210	R:R:P214	2.03	No	No	0	6	9
317	R:R:C109	R:R:G106	1.96	No	No	0	9	3
318	R:R:A150	R:R:G151	1.95	No	No	0	3	4
319	R:R:P183	R:R:P184	1.95	Yes	No	0	4	5
320	R:R:A303	R:R:G304	1.95	No	No	0	6	8
321	L:L:A50	L:L:C21	1.81	No	No	0	0	0
322	L:L:A26	L:L:A58	1.79	No	No	0	0	0
323	R:R:A66	R:R:A72	1.79	No	No	0	5	7
324	R:R:P270	R:R:S271	1.78	No	No	0	3	4
325	R:R:P297	R:R:V58	1.77	No	Yes	0	9	8
326	R:R:P25	R:R:T24	1.75	No	No	0	8	4
327	L:L:G44	L:L:L43	1.71	No	No	0	0	0
328	R:R:G54	R:R:L53	1.71	No	No	0	7	4
329	L:L:A58	L:L:V28	1.7	No	No	0	0	0
330	R:R:A303	R:R:V243	1.7	No	No	0	6	7
331	R:R:A249	R:R:V245	1.7	No	No	0	4	4
332	L:L:A38	L:L:T52	1.68	No	No	0	0	0
333	L:L:K49	L:L:P45	1.67	No	No	0	0	0
334	R:R:K140	R:R:P141	1.67	No	No	0	6	8
335	R:R:G309	R:R:Q308	1.64	No	No	0	5	8
336	L:L:A38	L:L:I48	1.62	No	No	0	0	0
337	L:L:S59	L:L:V56	1.62	No	No	0	0	0
338	R:R:A203	R:R:I263	1.62	No	No	0	5	5
339	R:R:A303	R:R:K239	1.61	No	Yes	0	6	7
340	L:L:V56	L:L:V57	1.6	No	No	0	0	0
341	R:R:V301	R:R:V58	1.6	No	Yes	0	6	8
342	R:R:V59	R:R:V80	1.6	No	No	0	7	5
343	R:R:C144	R:R:L136	1.59	No	No	0	5	5
344	R:R:T261	R:R:V260	1.59	Yes	No	0	4	6
345	L:L:E32	R:R:P273	1.57	No	No	0	0	2
346	R:R:T219	R:R:T223	1.57	No	No	0	4	2
347	L:L:I6	L:L:V57	1.54	Yes	No	0	0	0
348	R:R:I96	R:R:V97	1.54	No	No	0	5	3
349	R:R:I155	R:R:V159	1.54	No	No	0	2	1
350	R:R:I298	R:R:V302	1.54	No	No	0	7	6
351	R:R:K239	R:R:S237	1.53	Yes	No	0	7	7
352	R:R:F307	R:R:G306	1.51	No	No	0	9	7
353	R:R:L315	R:R:S314	1.5	No	No	0	6	4
354	R:R:L39	R:R:V42	1.49	No	No	0	5	5
355	R:R:L167	R:R:V205	1.49	No	No	0	4	3
356	R:R:N31	R:R:V35	1.48	No	Yes	0	1	3
357	R:R:D27	R:R:V26	1.46	No	No	0	9	5
358	R:R:N71	R:R:T69	1.46	No	No	0	7	7
359	R:R:I38	R:R:L41	1.43	No	No	0	5	5
360	R:R:I111	R:R:L115	1.43	No	No	0	4	5
361	R:R:I220	R:R:L216	1.43	No	No	0	3	2
362	R:R:Q98	R:R:T94	1.42	No	No	0	4	3
363	L:L:E35	L:L:T33	1.41	No	No	0	0	0
364	R:R:K280	R:R:L281	1.41	No	No	0	2	5
365	L:L:H15	L:L:V18	1.38	No	No	0	0	0
366	L:L:A63	L:L:R62	1.38	No	No	0	0	0
367	R:R:A201	R:R:R198	1.38	No	No	0	4	3
368	L:L:C22	L:L:Y13	1.34	No	Yes	0	0	0
369	R:R:R198	R:R:S193	1.32	No	No	0	3	4
370	R:R:R34	R:R:V35	1.31	No	Yes	0	2	3
371	R:R:R232	R:R:T235	1.29	No	No	0	5	4
372	R:R:F48	R:R:L49	1.22	Yes	No	0	6	4
373	R:R:Q308	R:R:R312	1.17	No	No	0	8	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:I6	4.78	4	2	0
2	L:L:Y13	6.3525	4	0	0
3	L:L:R37	9.48	4	4	0
4	L:L:L61	7.3425	4	0	0
5	L:L:H67	7.2	5	5	0
6	L:L:L72	4.53	4	0	0
7	L:L:R74	7.555	6	1	0
8	R:R:K28	9.78	5	4	3
9	R:R:T29	6.81	4	4	5
10	R:R:V35	3.04	4	0	3
11	R:R:F44	5.482	5	1	7
12	R:R:F48	5.1275	4	0	6
13	R:R:V58	2.4825	4	0	8
14	R:R:W60	5.1425	4	0	4
15	R:R:T62	3.9275	4	0	6
16	R:R:W74	7.922	5	0	7
17	R:R:L78	8.0125	4	3	9
18	R:R:D82	7.8	4	0	9
19	R:R:L89	7.7525	4	1	7
20	R:R:W102	8.2475	4	0	8
21	R:R:L112	6.2225	4	0	5
22	R:R:L118	4.755	4	0	5
23	R:R:M120	4.4175	4	1	7
24	R:R:R134	7.255	4	3	9
25	R:R:L137	6.0425	4	6	8
26	R:R:W161	4.5775	4	0	9
27	R:R:R175	5.335	6	0	5
28	R:R:F182	7.584	5	2	3
29	R:R:P183	5.1825	4	2	4
30	R:R:Y192	8.58	4	0	5
31	R:R:F211	5.95	6	1	8
32	R:R:Y222	9.19	5	0	8
33	R:R:T229	4.7975	4	0	8
34	R:R:K239	4.215	4	0	7
35	R:R:F251	5.8725	4	1	9
36	R:R:F254	9.062	5	8	8
37	R:R:W255	7.42571	7	1	9
38	R:R:Y258	6.46667	6	1	7
39	R:R:T261	4.1425	4	1	4
40	R:R:Y290	7.628	5	1	7
41	R:R:N296	7.6375	4	3	9
42	R:R:Y300	9.8525	4	3	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:I6	L:L:L2	52.5982	4.28	Yes	No	0	0	0
2	L:L:L2	L:L:L61	53.4104	16.61	No	Yes	0	0	0
3	R:R:F104	R:R:W102	10.6541	16.04	No	Yes	0	7	8
4	L:L:L72	R:R:W102	19.2701	3.42	Yes	Yes	0	0	8
5	L:L:L72	R:R:S95	69.9697	4.5	Yes	No	0	0	4
6	L:L:Q71	R:R:S95	69.2714	4.33	No	No	0	0	4
7	L:L:Q71	R:R:H100	63.4981	4.95	No	No	0	0	4
8	L:L:D69	R:R:H100	62.7532	16.39	No	No	0	0	4
9	L:L:D69	R:R:L187	62.0031	4.07	No	No	0	0	4
10	R:R:L187	R:R:R178	61.2478	10.93	No	No	0	4	2
11	L:L:H67	R:R:R178	60.4873	14.67	Yes	No	0	0	2
12	L:L:H67	L:L:I65	56.6074	2.65	Yes	No	0	0	0
13	L:L:I65	L:L:L61	55.8159	2.85	No	Yes	0	0	0
14	L:L:I6	R:R:F182	41.8923	10.05	Yes	Yes	2	0	3
15	L:L:A10	L:L:K19	35.3043	3.21	No	No	0	0	0
16	L:L:K19	L:L:Y23	36.22	2.39	No	No	0	0	0
17	L:L:Y23	R:R:F182	37.1304	12.38	No	Yes	0	0	3
18	L:L:A10	L:L:C22	34.3835	3.61	No	No	0	0	0
19	L:L:C22	L:L:Y13	32.5263	1.34	No	Yes	0	0	0
20	L:L:A50	L:L:Y13	26.8307	6.67	No	Yes	0	0	0
21	L:L:A50	L:L:C21	25.8633	1.81	No	No	0	0	0
22	L:L:C21	L:L:C47	24.8907	7.28	No	No	0	0	0
23	L:L:F51	L:L:I41	14.8806	8.79	No	No	0	0	0
24	L:L:I41	L:L:L43	19.9503	7.14	No	No	0	0	0
25	L:L:C47	L:L:L43	23.913	11.11	No	No	0	0	0
26	R:R:V190	R:R:Y192	23.675	17.66	No	Yes	0	5	5
27	R:R:R175	R:R:V190	24.6424	6.54	Yes	No	0	5	5
28	R:R:P113	R:R:R175	27.3143	4.32	No	Yes	0	6	5
29	L:L:L72	R:R:P113	31.7788	3.28	Yes	No	0	0	6
30	L:L:L72	R:R:L92	100	6.92	Yes	No	0	0	6
31	R:R:F44	R:R:L92	28.8844	3.65	Yes	No	1	7	6
32	R:R:F44	R:R:V286	22.6947	3.93	Yes	No	1	7	5
33	L:L:R74	R:R:V286	11.2853	5.23	Yes	No	1	0	5
34	R:R:V286	R:R:Y258	11.4431	6.31	No	Yes	1	5	7
35	R:R:L92	R:R:Y290	71.5269	3.52	No	Yes	1	6	7
36	R:R:M120	R:R:Y290	69.9154	5.99	Yes	Yes	1	7	7
37	L:L:R74	R:R:D282	16.7378	17.87	Yes	No	1	0	4
38	R:R:F44	R:R:S287	24.7691	7.93	Yes	No	0	7	4
39	R:R:A40	R:R:S287	21.9136	3.42	No	No	0	6	4
40	R:R:A40	R:R:L284	11.7302	4.73	No	No	0	6	4
41	R:R:F44	R:R:L89	17.7647	3.65	Yes	Yes	1	7	7
42	R:R:L89	R:R:Y290	14.7746	14.07	Yes	Yes	1	7	7
43	R:R:C86	R:R:L89	28.5585	4.76	No	Yes	0	5	7
44	R:R:C86	R:R:G51	27.8989	3.92	No	No	0	5	8
45	R:R:G51	R:R:N55	27.2497	3.39	No	No	0	8	9
46	R:R:D82	R:R:N55	14.2521	6.73	Yes	No	0	9	9
47	R:R:N55	R:R:P297	29.6707	16.29	No	No	0	9	9
48	R:R:P297	R:R:V58	26.1245	1.77	No	Yes	0	9	8
49	R:R:T62	R:R:V58	22.5318	3.17	Yes	Yes	0	6	8
50	R:R:L76	R:R:T62	12.7234	4.42	No	Yes	0	6	6
51	R:R:L76	R:R:V59	10.2196	2.98	No	No	0	6	7
52	R:R:M120	R:R:W255	66.0304	3.49	Yes	Yes	1	7	9
53	R:R:N292	R:R:W255	65.0061	13.56	No	Yes	0	9	9
54	R:R:L127	R:R:N292	64.6905	4.12	No	No	0	8	9
55	R:R:L127	R:R:L78	39.1118	4.15	No	Yes	3	8	9
56	R:R:I130	R:R:L78	30.4441	8.56	No	Yes	0	8	9
57	R:R:I130	R:R:W74	18.8976	3.52	No	Yes	0	8	7
58	R:R:D133	R:R:W74	14.9324	22.33	No	Yes	0	8	7
59	R:R:D133	R:R:L137	14.04	6.79	No	Yes	0	8	8
60	R:R:L126	R:R:L78	15.7394	15.22	No	Yes	0	7	9
61	R:R:C157	R:R:L126	13.9546	3.17	No	No	0	6	7
62	R:R:C157	R:R:N77	13.0597	11.02	No	No	0	6	9
63	R:R:L127	R:R:N296	25.3123	12.36	No	Yes	3	8	9
64	R:R:N296	R:R:Y300	27.7877	4.65	Yes	Yes	3	9	9
65	R:R:I130	R:R:R134	17.2603	6.26	No	Yes	0	8	9
66	R:R:R134	R:R:Y300	18.4786	10.29	Yes	Yes	3	9	9
67	R:R:N77	R:R:W161	10.5248	4.52	No	Yes	0	9	9
68	R:R:Y174	R:R:Y192	16.7585	2.98	No	Yes	0	4	5
69	R:R:L173	R:R:Y174	11.6629	4.69	No	No	0	4	4
70	R:R:I169	R:R:L173	10.6283	2.85	No	No	0	3	4
71	R:R:I124	R:R:W255	24.4381	12.92	No	Yes	0	8	9
72	R:R:I124	R:R:P214	23.6698	3.39	No	No	0	8	9
73	R:R:P214	R:R:W213	22.3197	6.76	No	No	0	9	5
74	R:R:T217	R:R:W213	19.9659	7.28	No	No	0	5	5
75	R:R:S131	R:R:T217	19.2416	3.2	No	No	0	9	5
76	R:R:S131	R:R:Y222	16.2412	12.72	No	Yes	0	9	8
77	R:R:R134	R:R:Y222	32.6324	9.26	Yes	Yes	0	9	8
78	R:R:F211	R:R:W255	16.5257	4.01	Yes	Yes	1	8	9
79	R:R:F211	R:R:L256	10.1161	3.65	Yes	No	0	8	5
80	R:R:V244	R:R:Y222	28.7473	12.62	No	Yes	0	7	8
81	R:R:L226	R:R:V244	26.5668	7.45	No	No	0	5	7
82	R:R:L226	R:R:L241	24.3812	5.54	No	No	0	5	6
83	R:R:L241	R:R:W230	17.7931	9.11	No	No	0	6	4
84	R:R:T229	R:R:W230	13.3752	3.64	Yes	No	0	8	4
85	R:R:I299	R:R:Y300	11.756	12.09	No	Yes	0	7	9
86	R:R:D282	R:R:M265	15.9153	9.7	No	No	0	4	4
87	R:R:F275	R:R:M265	13.0209	4.98	No	No	0	3	4
88	R:R:F275	R:R:L268	11.0654	13.4	No	No	0	3	2
89	L:L:R74	R:R:Y258	11.1999	12.35	Yes	Yes	1	0	7
90	R:R:W255	R:R:Y258	19.3011	5.79	Yes	Yes	1	9	7
91	R:R:D82	R:R:N296	13.026	9.42	Yes	Yes	0	9	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:Q3	R:R:Y181	10.15	0	No	No	0	1	0	1
L:L:I6	R:R:F182	10.05	2	Yes	Yes	0	3	0	1
L:L:K20	R:R:L22	4.23	0	No	No	0	3	0	1
L:L:K20	R:R:T24	4.5	0	No	No	0	4	0	1
L:L:Y23	R:R:F182	12.38	0	No	Yes	0	3	0	1
L:L:D24	R:R:D27	14.64	0	No	No	0	9	0	1
L:L:G25	R:R:D27	3.35	0	No	No	0	9	0	1
L:L:A26	R:R:F182	4.16	2	No	Yes	0	3	0	1
L:L:N29	R:R:K28	9.79	4	No	Yes	0	3	0	1
L:L:N29	R:R:T29	4.39	4	No	Yes	0	5	0	1
L:L:N30	R:R:L276	9.61	0	No	No	0	3	0	1
L:L:D31	R:R:K28	16.59	4	No	Yes	0	3	0	1
L:L:D31	R:R:T29	8.67	4	No	Yes	0	5	0	1
L:L:C34	R:R:K28	4.85	0	No	Yes	0	3	0	1
L:L:R37	R:R:K28	8.66	4	Yes	Yes	0	3	0	1
L:L:R37	R:R:T29	5.17	4	Yes	Yes	0	5	0	1
L:L:H67	R:R:V176	4.15	5	Yes	No	0	4	0	1
L:L:H67	R:R:R178	14.67	5	Yes	No	0	2	0	1
L:L:H67	R:R:G189	3.18	5	Yes	No	0	4	0	1
L:L:H67	R:R:D191	11.35	5	Yes	No	0	4	0	1
L:L:K68	R:R:Y192	3.58	0	No	Yes	0	5	0	1
L:L:D69	R:R:H100	16.39	0	No	No	0	4	0	1
L:L:D69	R:R:L187	4.07	0	No	No	0	4	0	1
L:L:M70	R:R:R175	3.72	0	No	Yes	0	5	0	1
L:L:Q71	R:R:S95	4.33	0	No	No	0	4	0	1
L:L:Q71	R:R:I96	8.23	0	No	No	0	5	0	1
L:L:Q71	R:R:H100	4.95	0	No	No	0	4	0	1
L:L:L72	R:R:L92	6.92	0	Yes	No	0	6	0	1
L:L:L72	R:R:S95	4.5	0	Yes	No	0	4	0	1
L:L:L72	R:R:W102	3.42	0	Yes	Yes	0	8	0	1
L:L:L72	R:R:P113	3.28	0	Yes	No	0	6	0	1
L:L:R74	R:R:Y258	12.35	1	Yes	Yes	0	7	0	1
L:L:R74	R:R:T261	3.88	1	Yes	Yes	0	4	0	1
L:L:R74	R:R:D282	17.87	1	Yes	No	0	4	0	1
L:L:R74	R:R:V286	5.23	1	Yes	No	0	5	0	1
R:R:K28	R:R:T29	9.01	4	Yes	Yes	3	5	1	1
R:R:F44	R:R:L92	3.65	1	Yes	No	7	6	2	1
R:R:F44	R:R:V286	3.93	1	Yes	No	7	5	2	1
R:R:F44	R:R:Y290	8.25	1	Yes	Yes	7	7	2	2
R:R:L92	R:R:Y290	3.52	1	No	Yes	6	7	1	2
R:R:F104	R:R:W102	16.04	0	No	Yes	7	8	2	1
R:R:L112	R:R:W102	5.69	0	Yes	Yes	5	8	2	1
R:R:C188	R:R:W102	7.84	0	No	Yes	9	8	2	1
R:R:L112	R:R:P113	4.93	0	Yes	No	5	6	2	1
R:R:P113	R:R:R175	4.32	0	No	Yes	6	5	1	1
R:R:M120	R:R:W255	3.49	1	Yes	Yes	7	9	2	2
R:R:M120	R:R:Y258	3.59	1	Yes	Yes	7	7	2	1
R:R:M120	R:R:Y290	5.99	1	Yes	Yes	7	7	2	2
R:R:R175	R:R:S171	9.22	0	Yes	No	5	5	1	2
R:R:C188	R:R:R175	5.57	0	No	Yes	9	5	2	1
R:R:R175	R:R:V190	6.54	0	Yes	No	5	5	1	2
R:R:D191	R:R:V176	13.15	5	No	No	4	4	1	1
R:R:L187	R:R:R178	10.93	0	No	No	4	2	1	1
R:R:E179	R:R:Y181	6.73	0	No	No	2	1	2	1
R:R:E180	R:R:F182	7	2	No	Yes	1	3	2	1
R:R:E180	R:R:P183	9.43	2	No	Yes	1	4	2	2
R:R:F182	R:R:P183	4.33	2	Yes	Yes	3	4	1	2
R:R:V190	R:R:Y192	17.66	0	No	Yes	5	5	2	1
R:R:D191	R:R:H194	8.82	5	No	No	4	1	1	2
R:R:E199	R:R:Y192	10.1	0	No	Yes	4	5	2	1
R:R:W255	R:R:Y258	5.79	1	Yes	Yes	9	7	2	1
R:R:A289	R:R:W255	5.19	1	No	Yes	8	9	2	2
R:R:Q259	R:R:Y258	6.76	0	No	Yes	8	7	2	1
R:R:V286	R:R:Y258	6.31	1	No	Yes	5	7	1	1
R:R:A289	R:R:Y258	4	1	No	Yes	8	7	2	1
R:R:D282	R:R:T261	4.34	1	No	Yes	4	4	1	1
R:R:C285	R:R:T261	6.76	0	No	Yes	6	4	2	1
R:R:D282	R:R:M265	9.7	1	No	No	4	4	1	2
R:R:P273	R:R:S272	3.56	0	No	No	2	4	1	2
R:R:K280	R:R:L276	8.46	0	No	No	2	3	2	1
L:L:R74	R:R:G262	3	1	Yes	No	0	5	0	1
R:R:Y174	R:R:Y192	2.98	0	No	Yes	4	5	2	1
L:L:S66	R:R:D195	2.94	0	No	No	0	3	0	1
R:R:R175	R:R:S110	2.64	0	Yes	No	5	6	1	2
R:R:P25	R:R:T24	1.75	0	No	No	8	4	2	1
R:R:T261	R:R:V260	1.59	1	Yes	No	4	6	1	2
L:L:E32	R:R:P273	1.57	0	No	No	0	2	0	1
R:R:I96	R:R:V97	1.54	0	No	No	5	3	1	2
R:R:D27	R:R:V26	1.46	0	No	No	9	5	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	8IA2_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.15
Number of Linked Nodes	347
Number of Links	373
Number of Hubs	42
Number of Links mediated by Hubs	160
Number of Communities	8
Number of Nodes involved in Communities	44
Number of Links involved in Communities	58

Path Summary
Number Of Nodes in MetaPath	92
Number Of Links MetaPath	91
Number of Shortest Paths	78525
Length Of Smallest Path	3
Average Path Length	17.7772
Length of Longest Path	45
Minimum Path Strength	1.35
Average Path Strength	6.6626
Maximum Path Strength	23.255
Minimum Path Correlation	0.7
Average Path Correlation	0.953207
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	2.77778
Average % Of Corr. Nodes	60.0849
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	35.2593
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain • Anaphylotoxins (complement system) • G protein-coupled receptor-like
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain • Anaphylotoxins (complement system) • G protein-coupled receptor-like
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P21730
Sequence	>8IA2_nogp_Chain_R L N T P V D K T S N T L R V P D I L A L V I F A V V F L V G V L G N A L V V W V T A F E A K R T I N A I W F L N L A V A D F L S C L A L P I L F T S I V Q H H H W P F G G A A C S I L P S L I L L N M Y A S I L L L A T I S A D R F L L V F K P I W C Q N F R G A G L A W I A C A V A W G L A L L L T I P S F L Y R V V R E E Y F P P K V L C G V D Y S H D K R R E R A V A I V R L V L G F L W P L L T L T I C Y T F I L L R T W S R R A T R S T K T L K V V V A V V A S F F I F W L P Y Q V T G I M M S F L E P S S P T F L L L K K L D S L C V S F A Y I N C C I N P I I Y V V A G Q G F Q G R L R K S L Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	5O9H	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	-	NDT9513727	-	2.7	2018-01-10	doi.org/10.1038/nature25025
	6C1Q	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	PMX53	NDT9513727	-	2.9	2018-05-30	doi.org/10.1038/s41594-018-0067-z
	6C1R	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	PMX53	Avacopan; Na	-	2.2	2018-05-30	doi.org/10.1038/s41594-018-0067-z
	8HPT	A	Peptide	Complement Peptide	C5a₁	Mus musculus	C5a anaphylatoxin C-terminal peptide	-	Go/β1/γ2	3.39	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	8HPT (No Gprot)	A	Peptide	Complement Peptide	C5a₁	Mus musculus	C5a anaphylatoxin C-terminal peptide	-		3.39	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	8HQC	A	Peptide	Complement Peptide	C5a₁	Mus musculus	C5a anaphylatoxin	-	Go/β1/γ2	3.89	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	8HQC (No Gprot)	A	Peptide	Complement Peptide	C5a₁	Mus musculus	C5a anaphylatoxin	-		3.89	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	8IA2	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	C5a anaphylatoxin	-	Go/β1/γ2	3.21	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	8IA2 (No Gprot)	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	C5a anaphylatoxin	-		3.21	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	8JZZ	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	C5a-desArg	-	Go/β1/γ2	3.31	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	8JZZ (No Gprot)	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	C5a-desArg	-		3.31	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	7Y64	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	C5a anaphylatoxin	-	Gi1/β1/γ2	2.9	2023-03-01	doi.org/10.1038/s41422-023-00779-2
	7Y64 (No Gprot)	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	C5a anaphylatoxin	-		2.9	2023-03-01	doi.org/10.1038/s41422-023-00779-2
	7Y65	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	C5a peptide	-	Gi1/β1/γ2	3.2	2023-03-01	doi.org/10.1038/s41422-023-00779-2
	7Y65 (No Gprot)	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	C5a peptide	-		3.2	2023-03-01	doi.org/10.1038/s41422-023-00779-2
	7Y66	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	BM213	-	Gi1/β1/γ2	2.9	2023-03-01	doi.org/10.1038/s41422-023-00779-2
	7Y66 (No Gprot)	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	BM213	-		2.9	2023-03-01	doi.org/10.1038/s41422-023-00779-2
	7Y67	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	C089 peptide	-	Gi1/β1/γ2	2.8	2023-03-01	doi.org/10.1038/s41422-023-00779-2
	7Y67 (No Gprot)	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	C089 peptide	-		2.8	2023-03-01	doi.org/10.1038/s41422-023-00779-2
	8HK5	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	Complement C5	-	Gi1/β1/γ2	3	2023-05-10	doi.org/10.1038/s41589-023-01339-w
	8HK5 (No Gprot)	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	Complement C5	-		3	2023-05-10	doi.org/10.1038/s41589-023-01339-w
	8JZP	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	C5A anaphylatoxin	-	Go/β1/γ2	3.54	2025-01-15	To be published
	8JZP (No Gprot)	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	C5A anaphylatoxin	-		3.54	2025-01-15	To be published

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Download 8IA2_nogp.zip

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