psnGPCR

Press and hold down the left mouse button and move the mouse to rotate.
Press and hold down the central mouse button and move the mouse to translate.
Use the mouse wheel to zoom in or out.
Click on any atom on your molecule and the corresponding residue label will be placed beneath the viewer.

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:D37	R:R:L33	4.07	No	No	0	4	4
2	R:R:H99	R:R:L33	2.57	No	No	0	2	4
3	R:R:K280	R:R:R34	18.56	No	No	0	2	2
4	R:R:P36	R:R:V35	3.53	Yes	No	0	3	3
5	R:R:D37	R:R:S283	2.94	No	No	0	4	4
6	R:R:A40	R:R:S283	3.42	No	No	0	6	4
7	R:R:A40	R:R:S287	3.42	No	No	0	6	4
8	R:R:F93	R:R:L41	4.87	No	No	0	7	5
9	R:R:I43	R:R:S287	7.74	No	No	0	5	4
10	R:R:F44	R:R:L89	15.83	No	No	0	7	7
11	R:R:F44	R:R:V286	2.62	No	Yes	0	7	5
12	R:R:F44	R:R:Y290	6.19	No	Yes	0	7	7
13	R:R:V47	R:R:Y290	2.52	No	Yes	0	6	7
14	R:R:C294	R:R:V47	3.42	Yes	No	0	7	6
15	R:R:F48	R:R:L49	3.65	Yes	No	0	6	4
16	R:R:F48	R:R:V52	3.93	Yes	No	0	6	5
17	R:R:F48	R:R:L89	6.09	Yes	No	0	6	7
18	R:R:F48	R:R:P90	7.22	Yes	No	0	6	9
19	R:R:C294	R:R:V50	3.42	Yes	No	0	7	6
20	R:R:F83	R:R:V52	3.93	No	No	0	8	5
21	R:R:D82	R:R:N55	13.46	No	No	0	9	9
22	R:R:F83	R:R:N55	6.04	No	No	0	8	9
23	R:R:N55	R:R:P297	4.89	No	No	0	9	9
24	R:R:L57	R:R:V61	2.98	No	No	0	5	6
25	R:R:F307	R:R:L57	3.65	Yes	No	2	9	5
26	R:R:L311	R:R:L57	5.54	No	No	2	6	5
27	R:R:S314	R:R:W60	6.18	No	No	0	4	4
28	R:R:R310	R:R:V61	3.92	Yes	No	0	4	6
29	R:R:L76	R:R:T62	5.9	No	No	0	6	6
30	R:R:E65	R:R:F64	8.16	No	No	0	5	4
31	R:R:F64	R:R:S314	11.89	No	No	0	4	4
32	R:R:E65	R:R:R310	8.14	No	Yes	0	5	4
33	R:R:E65	R:R:K313	4.05	No	No	0	5	4
34	R:R:A72	R:R:T69	3.36	No	No	0	7	7
35	R:R:I70	R:R:R148	11.27	No	No	0	6	7
36	R:R:A153	R:R:I73	3.25	No	Yes	0	7	6
37	R:R:I73	R:R:W154	10.57	Yes	No	0	6	3
38	R:R:T129	R:R:W74	3.64	No	Yes	0	6	7
39	R:R:I130	R:R:W74	5.87	No	Yes	0	8	7
40	R:R:D133	R:R:W74	10.05	No	Yes	0	8	7
41	R:R:A153	R:R:W74	5.19	No	Yes	0	7	7
42	R:R:A156	R:R:W74	2.59	No	Yes	0	5	7
43	R:R:C157	R:R:W74	3.92	No	Yes	0	6	7
44	R:R:F75	R:R:I130	5.02	No	No	0	8	8
45	R:R:F75	R:R:Y300	12.38	No	No	0	8	9
46	R:R:N77	R:R:W154	3.39	No	No	0	9	3
47	R:R:C157	R:R:N77	4.72	No	No	0	6	9
48	R:R:N77	R:R:W161	4.52	No	No	0	9	9
49	R:R:L126	R:R:L78	4.15	No	No	0	7	9
50	R:R:L127	R:R:L78	4.15	No	No	0	8	9
51	R:R:A81	R:R:W161	2.59	No	No	0	8	9
52	R:R:C293	R:R:D82	6.22	No	No	0	8	9
53	R:R:F83	R:R:L87	4.87	No	No	0	8	4
54	R:R:L84	R:R:N119	5.49	No	No	0	6	9
55	R:R:N119	R:R:S85	5.96	No	No	0	9	6
56	R:R:S85	R:R:Y290	5.09	No	Yes	0	6	7
57	R:R:F104	R:R:I91	3.77	Yes	No	0	7	6
58	R:R:I91	R:R:L112	5.71	No	No	0	6	5
59	R:R:T94	R:R:V97	3.17	No	No	0	3	3
60	R:R:Q98	R:R:T94	4.25	No	No	0	4	3
61	R:R:F104	R:R:T94	2.59	Yes	No	0	7	3
62	R:R:S95	R:R:W102	6.18	No	Yes	0	4	8
63	L:L:?4	R:R:I96	2.68	Yes	No	0	0	5
64	R:R:H101	R:R:Q98	7.42	No	No	3	4	4
65	R:R:P103	R:R:Q98	4.74	No	No	3	3	4
66	L:L:?4	R:R:H100	14.5	Yes	No	0	0	4
67	R:R:H101	R:R:P103	10.68	No	No	3	4	3
68	R:R:F104	R:R:W102	21.05	Yes	Yes	0	7	8
69	R:R:C109	R:R:W102	9.14	Yes	Yes	4	9	8
70	R:R:C188	R:R:W102	6.53	No	Yes	4	9	8
71	R:R:F104	R:R:P103	4.33	Yes	No	0	7	3
72	R:R:G106	R:R:V177	3.68	No	No	0	3	4
73	R:R:C109	R:R:P113	3.77	Yes	No	0	9	6
74	R:R:C109	R:R:R175	2.79	Yes	Yes	0	9	5
75	R:R:C109	R:R:C188	7.28	Yes	No	4	9	9
76	R:R:L112	R:R:P113	3.28	No	No	0	5	6
77	R:R:S114	R:R:S171	6.52	No	No	0	5	5
78	R:R:F172	R:R:S114	5.28	No	No	0	4	5
79	R:R:R175	R:R:S114	3.95	Yes	No	0	5	5
80	R:R:L117	R:R:Y121	4.69	No	No	5	4	7
81	R:R:L117	R:R:S171	3	No	No	0	4	5
82	R:R:L117	R:R:R206	3.64	No	No	5	4	6
83	R:R:L118	R:R:N119	4.12	Yes	No	0	5	9
84	R:R:A164	R:R:L118	3.15	No	Yes	0	7	5
85	R:R:L118	R:R:L165	4.15	Yes	No	0	5	4
86	R:R:L118	R:R:T168	10.32	Yes	No	0	5	6
87	R:R:M120	R:R:W255	5.82	No	Yes	0	7	9
88	R:R:L167	R:R:Y121	4.69	No	No	0	4	7
89	R:R:R206	R:R:Y121	12.35	No	No	5	6	7
90	R:R:A122	R:R:W161	5.19	No	No	0	6	9
91	R:R:I124	R:R:P214	3.39	Yes	Yes	0	8	9
92	R:R:F251	R:R:I124	3.77	Yes	Yes	6	9	8
93	R:R:I124	R:R:W255	4.7	Yes	Yes	6	8	9
94	R:R:L125	R:R:L163	5.54	No	No	0	6	4
95	R:R:I130	R:R:R134	5.01	No	No	0	8	9
96	R:R:L218	R:R:S131	3	No	No	0	8	9
97	R:R:C221	R:R:S131	3.44	No	No	0	6	9
98	R:R:S131	R:R:Y222	8.9	No	Yes	0	9	8
99	R:R:D133	R:R:L137	2.71	No	No	0	8	8
100	R:R:R134	R:R:Y222	4.12	No	Yes	0	9	8
101	R:R:F135	R:R:F139	10.72	No	No	0	8	7
102	R:R:C221	R:R:F135	6.98	No	No	0	6	8
103	R:R:F135	R:R:F224	4.29	No	No	0	8	3
104	R:R:C144	R:R:L137	3.17	No	No	0	5	8
105	R:R:L137	R:R:R148	9.72	No	No	0	8	7
106	R:R:F139	R:R:V138	3.93	No	No	7	7	8
107	R:R:I225	R:R:V138	7.68	No	No	0	8	8
108	R:R:R228	R:R:V138	2.62	No	No	7	5	8
109	R:R:F139	R:R:R228	21.38	No	No	7	7	5
110	R:R:C144	R:R:W143	2.61	No	No	0	5	5
111	R:R:F147	R:R:W143	7.02	No	No	0	4	5
112	R:R:N146	R:R:Q145	2.64	No	No	0	5	5
113	R:R:F147	R:R:N146	3.62	No	No	0	4	5
114	R:R:F172	R:R:T168	5.19	No	No	0	4	6
115	R:R:I169	R:R:P170	3.39	No	No	0	3	8
116	R:R:F172	R:R:I169	2.51	No	No	0	4	3
117	R:R:I169	R:R:L173	2.85	No	No	0	3	4
118	R:R:P170	R:R:V202	3.53	No	No	0	8	5
119	R:R:L173	R:R:Y174	4.69	No	No	0	4	4
120	R:R:Y174	R:R:Y192	7.94	No	No	0	4	5
121	R:R:D195	R:R:Y174	3.45	No	No	0	3	4
122	R:R:G189	R:R:R175	4.5	No	Yes	0	4	5
123	R:R:R175	R:R:V190	2.62	Yes	No	0	5	5
124	R:R:D191	R:R:V176	4.38	No	No	0	4	4
125	R:R:C188	R:R:V177	5.12	No	No	0	9	4
126	L:L:?1	R:R:R178	5.26	Yes	No	0	0	2
127	R:R:E179	R:R:V186	5.7	No	No	0	2	6
128	L:L:?1	R:R:L187	5.99	Yes	No	0	0	4
129	L:L:?1	R:R:G189	2.96	Yes	No	0	0	4
130	R:R:V190	R:R:Y192	3.79	No	No	0	5	5
131	R:R:D191	R:R:S193	2.94	No	No	0	4	4
132	L:L:?1	R:R:D191	3.52	Yes	No	0	0	4
133	R:R:E199	R:R:Y192	16.83	No	No	0	4	5
134	R:R:D195	R:R:R198	7.15	No	No	0	3	3
135	L:L:K2	R:R:E199	5.4	Yes	No	0	0	4
136	R:R:F267	R:R:R200	5.34	No	No	0	4	3
137	R:R:A203	R:R:S266	3.42	No	No	0	5	5
138	R:R:F267	R:R:I204	3.77	No	No	0	4	3
139	R:R:L207	R:R:Q259	6.65	No	No	0	5	8
140	R:R:I263	R:R:L207	5.71	No	No	0	5	5
141	R:R:G210	R:R:L209	3.42	No	No	0	6	4
142	R:R:F211	R:R:L212	2.44	Yes	No	0	8	4
143	R:R:F211	R:R:L215	2.44	Yes	No	0	8	5
144	R:R:F211	R:R:L256	2.44	Yes	No	0	8	5
145	R:R:F211	R:R:Q259	7.03	Yes	No	0	8	8
146	R:R:P214	R:R:W213	6.76	Yes	No	0	9	5
147	R:R:T217	R:R:W213	4.85	No	No	0	5	5
148	R:R:F251	R:R:L215	3.65	Yes	No	0	9	5
149	R:R:F252	R:R:L215	3.65	No	No	0	5	5
150	R:R:L216	R:R:T219	2.95	No	No	0	2	4
151	R:R:F251	R:R:L218	2.44	Yes	No	0	9	8
152	R:R:F224	R:R:I220	3.77	No	No	0	3	3
153	R:R:V244	R:R:Y222	15.14	No	Yes	0	7	8
154	R:R:V248	R:R:Y222	2.52	No	Yes	0	7	8
155	R:R:L226	R:R:W230	4.56	No	No	0	5	4
156	R:R:L226	R:R:L241	4.15	No	No	0	5	6
157	R:R:R236	R:R:W230	3	No	No	0	5	4
158	R:R:R233	R:R:R236	4.26	No	No	0	4	5
159	R:R:K239	R:R:V243	3.04	No	No	0	7	7
160	R:R:A303	R:R:K239	3.21	No	No	0	6	7
161	R:R:L241	R:R:V245	2.98	No	No	0	6	4
162	R:R:F251	R:R:W255	6.01	Yes	Yes	6	9	9
163	R:R:F252	R:R:L256	4.87	No	No	0	5	5
164	R:R:F254	R:R:F288	5.36	Yes	No	0	8	8
165	R:R:F254	R:R:I291	15.07	Yes	No	0	8	5
166	R:R:W255	R:R:Y258	7.72	Yes	No	0	9	7
167	R:R:A289	R:R:W255	5.19	No	Yes	0	8	9
168	R:R:N292	R:R:W255	7.91	No	Yes	0	9	9
169	R:R:L256	R:R:P257	3.28	No	No	0	5	9
170	R:R:Q259	R:R:Y258	5.64	No	No	0	8	7
171	L:L:?6	R:R:Y258	14.03	Yes	No	0	0	7
172	R:R:G262	R:R:T261	3.64	No	Yes	1	5	4
173	R:R:C285	R:R:T261	8.45	No	Yes	0	6	4
174	L:L:?6	R:R:T261	3.53	Yes	Yes	1	0	4
175	L:L:?6	R:R:G262	4.09	Yes	No	1	0	5
176	R:R:F267	R:R:I263	8.79	No	No	0	4	5
177	R:R:L278	R:R:M265	5.65	No	No	0	4	4
178	R:R:D282	R:R:M265	6.93	Yes	No	0	4	4
179	R:R:L268	R:R:S272	3	No	No	0	2	4
180	R:R:L268	R:R:T274	5.9	No	No	0	2	1
181	R:R:E269	R:R:P270	9.43	No	No	0	3	3
182	R:R:E269	R:R:S271	5.75	No	No	0	3	4
183	R:R:F275	R:R:P270	4.33	Yes	No	0	3	3
184	R:R:F275	R:R:K279	7.44	Yes	No	8	3	4
185	L:L:K2	R:R:F275	2.48	Yes	Yes	8	0	3
186	L:L:K2	R:R:K279	2.87	Yes	No	8	0	4
187	L:L:P3	R:R:K279	3.35	No	No	0	0	4
188	R:R:D282	R:R:V286	4.38	Yes	Yes	1	4	5
189	L:L:W5	R:R:D282	5.58	Yes	Yes	1	0	4
190	L:L:?6	R:R:D282	8.66	Yes	Yes	1	0	4
191	L:L:W5	R:R:V286	22.07	Yes	Yes	1	0	5
192	L:L:?6	R:R:V286	5.94	Yes	Yes	1	0	5
193	R:R:C294	R:R:I291	3.27	Yes	No	0	7	5
194	R:R:N292	R:R:N296	8.17	No	No	0	9	9
195	R:R:I295	R:R:I299	2.94	No	No	0	7	7
196	R:R:R310	R:R:Y300	6.17	Yes	No	0	4	9
197	R:R:F307	R:R:V301	7.87	Yes	No	0	9	6
198	R:R:F307	R:R:R310	3.21	Yes	Yes	0	9	4
199	R:R:F307	R:R:L311	3.65	Yes	No	2	9	6
200	R:R:Q308	R:R:R312	3.5	No	No	0	8	5
201	L:L:?1	L:L:K2	9.76	Yes	Yes	0	0	0
202	L:L:?1	L:L:P3	4.26	Yes	No	0	0	0
203	L:L:?4	L:L:W5	4.28	Yes	Yes	0	0	0
204	L:L:?6	L:L:W5	9.09	Yes	Yes	1	0	0
205	R:R:L311	R:R:R312	2.43	No	No	0	6	5
206	R:R:F75	R:R:N71	2.42	No	No	0	8	7
207	R:R:L136	R:R:W143	2.28	No	No	0	5	5
208	R:R:G105	R:R:G106	2.11	No	No	0	7	3
209	R:R:G210	R:R:P214	2.03	No	Yes	0	6	9
210	R:R:C86	R:R:G51	1.96	No	No	0	5	8
211	R:R:A128	R:R:P214	1.87	No	Yes	0	7	9
212	R:R:P273	R:R:S272	1.78	No	No	0	2	4
213	R:R:P297	R:R:V58	1.77	No	No	0	9	8
214	R:R:C86	R:R:V52	1.71	No	No	0	5	5
215	R:R:G54	R:R:L53	1.71	No	No	0	7	4
216	R:R:G162	R:R:L165	1.71	No	No	0	4	4
217	R:R:A79	R:R:V58	1.7	No	No	0	8	8
218	R:R:A79	R:R:V59	1.7	No	No	0	8	7
219	R:R:A72	R:R:T62	1.68	No	No	0	7	6
220	R:R:A160	R:R:T129	1.68	No	No	0	6	6
221	R:R:K140	R:R:P141	1.67	No	No	0	6	8
222	R:R:L284	R:R:P36	1.64	No	Yes	0	4	3
223	R:R:C294	R:R:I298	1.64	Yes	No	0	7	7
224	R:R:A66	R:R:I73	1.62	No	Yes	0	5	6
225	R:R:A150	R:R:I73	1.62	No	Yes	0	3	6
226	R:R:A203	R:R:I263	1.62	No	No	0	5	5
227	R:R:A249	R:R:I253	1.62	No	No	0	4	5
228	R:R:A303	R:R:I299	1.62	No	No	0	6	7
229	R:R:D37	R:R:P36	1.61	No	Yes	0	4	3
230	R:R:V59	R:R:V80	1.6	No	No	0	7	5
231	R:R:V177	R:R:V186	1.6	No	No	0	4	6
232	R:R:V243	R:R:V247	1.6	No	No	0	7	7
233	R:R:T219	R:R:V248	1.59	No	No	0	4	7
234	R:R:T240	R:R:V244	1.59	No	No	0	7	7
235	R:R:T261	R:R:V260	1.59	Yes	No	0	4	6
236	R:R:C285	R:R:L281	1.59	No	No	0	6	5
237	R:R:A63	R:R:L76	1.58	No	No	0	3	6
238	R:R:A66	R:R:L76	1.58	No	No	0	5	6
239	R:R:A160	R:R:L125	1.58	No	No	0	6	6
240	R:R:A160	R:R:L126	1.58	No	No	0	6	7
241	R:R:T229	R:R:T235	1.57	No	No	0	8	4
242	R:R:I124	R:R:S123	1.55	Yes	No	0	8	9
243	R:R:I38	R:R:V42	1.54	No	No	0	5	5
244	R:R:I298	R:R:V302	1.54	No	No	0	7	6
245	R:R:K239	R:R:S237	1.53	No	No	0	7	7
246	R:R:I225	R:R:T229	1.52	No	No	0	8	8
247	R:R:M264	R:R:V260	1.52	No	No	0	4	6
248	R:R:G149	R:R:R148	1.5	No	No	0	5	7
249	R:R:G304	R:R:R310	1.5	No	Yes	0	8	4
250	R:R:L212	R:R:V208	1.49	No	No	0	4	4
251	R:R:I291	R:R:I295	1.47	No	No	0	5	7
252	R:R:I295	R:R:I298	1.47	No	No	0	7	7
253	R:R:P36	R:R:R34	1.44	Yes	No	0	3	2
254	R:R:I38	R:R:L33	1.43	No	No	0	5	4
255	R:R:I38	R:R:L39	1.43	No	No	0	5	5
256	R:R:G151	R:R:W154	1.41	No	No	0	4	3
257	R:R:A108	R:R:F104	1.39	No	Yes	0	5	7
258	R:R:H194	R:R:S193	1.39	No	No	0	1	4
259	R:R:L277	R:R:L281	1.38	No	No	0	1	5
260	R:R:E269	R:R:K196	1.35	No	No	0	3	2
261	R:R:A116	R:R:Y290	1.33	No	Yes	0	6	7
262	R:R:F254	R:R:S250	1.32	Yes	No	0	8	6
263	R:R:F275	R:R:S272	1.32	Yes	No	0	3	4
264	L:L:?4	R:R:L92	1.3	Yes	No	0	0	6
265	R:R:R68	R:R:T69	1.29	No	No	0	7	7
266	R:R:R232	R:R:T235	1.29	No	No	0	5	4
267	R:R:F252	R:R:I253	1.26	No	No	0	5	5
268	R:R:F254	R:R:I253	1.26	Yes	No	0	8	5
269	R:R:T229	R:R:W230	1.21	No	No	0	8	4
270	R:R:R197	R:R:R198	1.07	No	No	0	1	3

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:P36	2.055	4	0	3
2	R:R:F48	5.2225	4	0	6
3	R:R:I73	4.265	4	0	6
4	R:R:W74	5.21	6	0	7
5	R:R:W102	10.725	4	4	8
6	R:R:F104	6.626	5	0	7
7	R:R:C109	5.745	4	4	9
8	R:R:L118	5.435	4	0	5
9	R:R:I124	3.3525	4	6	8
10	R:R:R175	3.465	4	0	5
11	R:R:F211	3.5875	4	0	8
12	R:R:P214	3.5125	4	0	9
13	R:R:Y222	7.67	4	0	8
14	R:R:F251	3.9675	4	6	9
15	R:R:F254	5.7525	4	0	8
16	R:R:W255	6.225	6	6	9
17	R:R:T261	4.3025	4	1	4
18	R:R:F275	3.8925	4	8	3
19	R:R:D282	6.3875	4	1	4
20	R:R:V286	8.7525	4	1	5
21	R:R:Y290	3.7825	4	0	7
22	R:R:C294	2.9375	4	0	7
23	R:R:F307	4.595	4	2	9
24	R:R:R310	4.588	5	0	4
25	L:L:?1	5.29167	6	0	0
26	L:L:K2	5.1275	4	8	0
27	L:L:?4	5.69	4	0	0
28	L:L:W5	10.255	4	1	0
29	L:L:?6	7.55667	6	1	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:F44	R:R:Y290	84.0375	6.19	No	Yes	0	7	7
2	R:R:V47	R:R:Y290	22.3604	2.52	No	Yes	0	6	7
3	R:R:C294	R:R:V47	21.6527	3.42	Yes	No	0	7	6
4	R:R:F44	R:R:L89	28.4295	15.83	No	No	0	7	7
5	R:R:F48	R:R:L89	26.8711	6.09	Yes	No	0	6	7
6	R:R:F48	R:R:V52	22.1102	3.93	Yes	No	0	6	5
7	R:R:F83	R:R:V52	17.2207	3.93	No	No	0	8	5
8	R:R:F83	R:R:N55	13.8895	6.04	No	No	0	8	9
9	R:R:F44	R:R:V286	88.541	2.62	No	Yes	0	7	5
10	L:L:?6	R:R:V286	82.5077	5.94	Yes	Yes	1	0	5
11	L:L:?6	R:R:Y258	90.0994	14.03	Yes	No	0	0	7
12	R:R:W255	R:R:Y258	83.3298	7.72	Yes	No	0	9	7
13	R:R:F251	R:R:W255	76.0812	6.01	Yes	Yes	6	9	9
14	R:R:F251	R:R:L218	100	2.44	Yes	No	0	9	8
15	R:R:L218	R:R:S131	99.471	3	No	No	0	8	9
16	R:R:S131	R:R:Y222	85.989	8.9	No	Yes	0	9	8
17	R:R:R134	R:R:Y222	80.3846	4.12	No	Yes	0	9	8
18	R:R:I130	R:R:R134	79.4839	5.01	No	No	0	8	9
19	R:R:F75	R:R:I130	29.2301	5.02	No	No	0	8	8
20	R:R:F75	R:R:Y300	26.2278	12.38	No	No	0	8	9
21	R:R:R310	R:R:Y300	24.7909	6.17	Yes	No	0	4	9
22	R:R:F307	R:R:R310	10.3367	3.21	Yes	Yes	0	9	4
23	R:R:I130	R:R:W74	59.1107	5.87	No	Yes	0	8	7
24	R:R:A153	R:R:W74	20.1658	5.19	No	Yes	0	7	7
25	R:R:A153	R:R:I73	18.5574	3.25	No	Yes	0	7	6
26	R:R:A66	R:R:I73	12.2525	1.62	No	Yes	0	5	6
27	R:R:A66	R:R:L76	10.544	1.58	No	No	0	5	6
28	R:R:D133	R:R:W74	18.7933	10.05	No	Yes	0	8	7
29	R:R:D133	R:R:L137	17.1563	2.71	No	No	0	8	8
30	R:R:C157	R:R:W74	11.8021	3.92	No	Yes	0	6	7
31	R:R:C157	R:R:N77	10.1651	4.72	No	No	0	6	9
32	R:R:T129	R:R:W74	12.2739	3.64	No	Yes	0	6	7
33	R:R:A160	R:R:T129	10.5869	1.68	No	No	0	6	6
34	R:R:S85	R:R:Y290	90.1494	5.09	No	Yes	0	6	7
35	R:R:N119	R:R:S85	89.3631	5.96	No	No	0	9	6
36	R:R:F104	R:R:W102	15.3764	21.05	Yes	Yes	0	7	8
37	R:R:C109	R:R:W102	18.1643	9.14	Yes	Yes	4	9	8
38	R:R:C109	R:R:R175	34.1554	2.79	Yes	Yes	0	9	5
39	R:R:R175	R:R:S114	64.2362	3.95	Yes	No	0	5	5
40	R:R:F172	R:R:S114	70.5769	5.28	No	No	0	4	5
41	R:R:F172	R:R:T168	83.4584	5.19	No	No	0	4	6
42	R:R:L118	R:R:T168	84.3448	10.32	Yes	No	0	5	6
43	R:R:L118	R:R:N119	87.7475	4.12	Yes	No	0	5	9
44	R:R:I124	R:R:P214	10.2009	3.39	Yes	Yes	0	8	9
45	R:R:C221	R:R:S131	28.3008	3.44	No	No	0	6	9
46	R:R:C221	R:R:F135	26.7281	6.98	No	No	0	6	8
47	R:R:F135	R:R:F139	21.9172	10.72	No	No	0	8	7
48	R:R:C144	R:R:L137	10.5869	3.17	No	No	0	5	8
49	R:R:F139	R:R:V138	18.7576	3.93	No	No	7	7	8
50	R:R:I225	R:R:V138	17.1635	7.68	No	No	0	8	8
51	R:R:F172	R:R:I169	14.4471	2.51	No	No	0	4	3
52	R:R:I169	R:R:L173	10.0579	2.85	No	No	0	3	4
53	R:R:G189	R:R:R175	32.1467	4.5	No	Yes	0	4	5
54	L:L:?1	R:R:G189	30.667	2.96	Yes	No	0	0	4
55	L:L:?1	L:L:K2	17.5495	9.76	Yes	Yes	0	0	0
56	R:R:I263	R:R:L207	14.7902	5.71	No	No	0	5	5
57	R:R:L207	R:R:Q259	17.2064	6.65	No	No	0	5	8
58	R:R:Q259	R:R:Y258	18.5217	5.64	No	No	0	8	7
59	R:R:F211	R:R:Q259	13.7966	7.03	Yes	No	0	8	8
60	R:R:F251	R:R:L215	26.4422	3.65	Yes	No	0	9	5
61	R:R:F211	R:R:L215	11.4947	2.44	Yes	No	0	8	5
62	R:R:F252	R:R:L215	19.7369	3.65	No	No	0	5	5
63	R:R:F252	R:R:I253	21.1666	1.26	No	No	0	5	5
64	R:R:F254	R:R:I253	20.1944	1.26	Yes	No	0	8	5
65	R:R:F254	R:R:I291	19.5511	15.07	Yes	No	0	8	5
66	R:R:C294	R:R:I291	16.5559	3.27	Yes	No	0	7	5
67	R:R:I225	R:R:T229	15.4979	1.52	No	No	0	8	8
68	R:R:T229	R:R:W230	10.3939	1.21	No	No	0	8	4
69	R:R:I291	R:R:I295	13.9181	1.47	No	No	0	5	7
70	R:R:I295	R:R:I299	15.1333	2.94	No	No	0	7	7
71	R:R:A303	R:R:I299	12.5956	1.62	No	No	0	6	7
72	R:R:A303	R:R:K239	10.0436	3.21	No	No	0	6	7
73	L:L:?6	R:R:T261	10.9729	3.53	Yes	Yes	1	0	4
74	L:L:K2	R:R:F275	14.8545	2.48	Yes	Yes	8	0	3

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:F44	R:R:V286	2.62	0	No	Yes	7	5	2	1
L:L:?4	R:R:I96	2.68	0	Yes	No	0	5	0	1
L:L:?4	R:R:H100	14.5	0	Yes	No	0	4	0	1
R:R:G189	R:R:R175	4.5	0	No	Yes	4	5	1	2
R:R:D191	R:R:V176	4.38	0	No	No	4	4	1	2
L:L:?1	R:R:R178	5.26	0	Yes	No	0	2	0	1
L:L:?1	R:R:L187	5.99	0	Yes	No	0	4	0	1
L:L:?1	R:R:G189	2.96	0	Yes	No	0	4	0	1
R:R:D191	R:R:S193	2.94	0	No	No	4	4	1	2
L:L:?1	R:R:D191	3.52	0	Yes	No	0	4	0	1
R:R:E199	R:R:Y192	16.83	0	No	No	4	5	1	2
L:L:K2	R:R:E199	5.4	8	Yes	No	0	4	0	1
R:R:W255	R:R:Y258	7.72	6	Yes	No	9	7	2	1
R:R:Q259	R:R:Y258	5.64	0	No	No	8	7	2	1
L:L:?6	R:R:Y258	14.03	1	Yes	No	0	7	0	1
R:R:G262	R:R:T261	3.64	1	No	Yes	5	4	1	1
R:R:C285	R:R:T261	8.45	0	No	Yes	6	4	2	1
L:L:?6	R:R:T261	3.53	1	Yes	Yes	0	4	0	1
L:L:?6	R:R:G262	4.09	1	Yes	No	0	5	0	1
R:R:D282	R:R:M265	6.93	1	Yes	No	4	4	1	2
R:R:F275	R:R:P270	4.33	8	Yes	No	3	3	1	2
R:R:F275	R:R:K279	7.44	8	Yes	No	3	4	1	1
L:L:K2	R:R:F275	2.48	8	Yes	Yes	0	3	0	1
L:L:K2	R:R:K279	2.87	8	Yes	No	0	4	0	1
L:L:P3	R:R:K279	3.35	0	No	No	0	4	0	1
R:R:D282	R:R:V286	4.38	1	Yes	Yes	4	5	1	1
L:L:W5	R:R:D282	5.58	1	Yes	Yes	0	4	0	1
L:L:?6	R:R:D282	8.66	1	Yes	Yes	0	4	0	1
L:L:W5	R:R:V286	22.07	1	Yes	Yes	0	5	0	1
L:L:?6	R:R:V286	5.94	1	Yes	Yes	0	5	0	1
R:R:T261	R:R:V260	1.59	1	Yes	No	4	6	1	2
R:R:F275	R:R:S272	1.32	8	Yes	No	3	4	1	2
L:L:?4	R:R:L92	1.3	0	Yes	No	0	6	0	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	7Y67_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	2.44
Number of Linked Nodes	253
Number of Links	270
Number of Hubs	29
Number of Links mediated by Hubs	108
Number of Communities	8
Number of Nodes involved in Communities	27
Number of Links involved in Communities	30

Path Summary
Number Of Nodes in MetaPath	75
Number Of Links MetaPath	74
Number of Shortest Paths	30832
Length Of Smallest Path	3
Average Path Length	15.2991
Length of Longest Path	35
Minimum Path Strength	1.26
Average Path Strength	5.40385
Maximum Path Strength	16.05
Minimum Path Correlation	0.7
Average Path Correlation	0.92088
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	3.22581
Average % Of Corr. Nodes	44.7351
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	32.8414
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• G protein-coupled receptor-like • Transducin (heterotrimeric G protein), gamma chain • Ras-like P-loop GTPases
SCOP2	Family Identifier	• G protein-coupled receptor-like • Transducin (heterotrimeric G protein), gamma chain • Ras-like P-loop GTPases
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	MEA
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	MEA
Name	N-METHYLPHENYLALANINE
Synonyms
Identifier
Formula	C10 H13 N O2
Molecular Weight	179.216
SMILES
PubChem	6951135
Formal Charge	0
Total Atoms	26
Total Chiral Atoms	1
Total Bonds	26
Total Aromatic Bonds	6


Code	ZAL
PDB Residues	L:L:?4
Environment Details	Open EMBL-EBI Page
Code	ZAL
Name	3-cyclohexyl-D-alanine
Synonyms
Identifier
Formula	C9 H17 N O2
Molecular Weight	171.237
SMILES
PubChem	736026
Formal Charge	0
Total Atoms	29
Total Chiral Atoms	1
Total Bonds	29
Total Aromatic Bonds	0


Code	DAR
PDB Residues	L:L:?6
Environment Details	Open EMBL-EBI Page
Code	DAR
Name	D-arginine
Synonyms	(2R)-2-amino-5-guanidinopentanoic acid
Identifier
Formula	C6 H15 N4 O2
Molecular Weight	175.209
SMILES
PubChem	17753939
Formal Charge	1
Total Atoms	27
Total Chiral Atoms	1
Total Bonds	26
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P21730
Sequence	>7Y67_nogp_Chain_R T L R V P D I L A L V I F A V V F L V G V L G N A L V V W V T A F E A K R T I N A I W F L N L A V A D F L S C L A L P I L F T S I V Q H H H W P F G G A A C S I L P S L A L L N M Y A S I L L L A T I S A D R F L L V F K P I W C Q N F R G A G L A W I A C A V A W G L A L L L T I P S F L Y R V V R E E V L C G V D Y S H D K R R E R A V A I V R L V L G F L W P L L T L T I C Y T F I L L R T W S R R A T R S T K T L K V V V A V V A S F F I F W L P Y Q V T G I M M S F L E P S S P T F L L L K K L D S L C V S F A Y I N C C I N P I I Y V V A G Q G F Q G R L R K S Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	5O9H	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	-	NDT9513727	-	2.7	2018-01-10	doi.org/10.1038/nature25025
	6C1Q	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	PMX53	NDT9513727	-	2.9	2018-05-30	doi.org/10.1038/s41594-018-0067-z
	6C1R	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	PMX53	Avacopan; Na	-	2.2	2018-05-30	doi.org/10.1038/s41594-018-0067-z
	7Y64	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	C5a	-	Gi1/β1/γ2	2.9	2023-03-01	doi.org/10.1038/s41422-023-00779-2
	7Y64 (No Gprot)	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	C5a	-		2.9	2023-03-01	doi.org/10.1038/s41422-023-00779-2
	7Y65	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	C5a (C-terminal peptide)	-	Gi1/β1/γ2	3.2	2023-03-01	doi.org/10.1038/s41422-023-00779-2
	7Y65 (No Gprot)	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	C5a (C-terminal peptide)	-		3.2	2023-03-01	doi.org/10.1038/s41422-023-00779-2
	7Y66	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	BM213	-	Gi1/β1/γ2	2.9	2023-03-01	doi.org/10.1038/s41422-023-00779-2
	7Y66 (No Gprot)	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	BM213	-		2.9	2023-03-01	doi.org/10.1038/s41422-023-00779-2
	7Y67	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	C089 peptide	-	Gi1/β1/γ2	2.8	2023-03-01	doi.org/10.1038/s41422-023-00779-2
	7Y67 (No Gprot)	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	C089 peptide	-		2.8	2023-03-01	doi.org/10.1038/s41422-023-00779-2
	8HK5	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	C5a	-	Gi1/β1/γ2	3	2023-05-10	doi.org/10.1038/s41589-023-01339-w
	8HK5 (No Gprot)	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	C5a	-		3	2023-05-10	doi.org/10.1038/s41589-023-01339-w
	8HPT	A	Peptide	Complement Peptide	C5a₁	Mus musculus	C5a (C-terminal peptide)	-	Go/β1/γ2	3.39	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	8HPT (No Gprot)	A	Peptide	Complement Peptide	C5a₁	Mus musculus	C5a (C-terminal peptide)	-		3.39	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	8HQC	A	Peptide	Complement Peptide	C5a₁	Mus musculus	C5a	-	Go/β1/γ2	3.89	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	8HQC (No Gprot)	A	Peptide	Complement Peptide	C5a₁	Mus musculus	C5a	-		3.89	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	8IA2	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	C5a	-	Go/β1/γ2	3.21	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	8IA2 (No Gprot)	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	C5a	-		3.21	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	8JZZ	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	C5a-des-Arg	-	Go/β1/γ2	3.31	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	8JZZ (No Gprot)	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	C5a-des-Arg	-		3.31	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	9KWG	A	Peptide	Complement Peptide	C5a₁	Mus musculus	C5a	-	Go/β1/γ2	3.15	2025-11-26	10.1101/2025.05.26.656101
	9KWG (No Gprot)	A	Peptide	Complement Peptide	C5a₁	Mus musculus	C5a	-		3.15	2025-11-26	10.1101/2025.05.26.656101
	9KWX	A	Peptide	Complement Peptide	C5a₁	Mus musculus	C5a-des-Arg	-	Go/β1/γ2	3.13	2025-11-26	10.1101/2025.05.26.656101
	9KWX (No Gprot)	A	Peptide	Complement Peptide	C5a₁	Mus musculus	C5a-des-Arg	-		3.13	2025-11-26	10.1101/2025.05.26.656101
	9KX6	A	Peptide	Complement Peptide	C5a₁	Mus musculus	C5a-des-Arg	-	Go/β1/γ2	3.11	2025-11-26	10.1101/2025.05.26.656101
	9KX6 (No Gprot)	A	Peptide	Complement Peptide	C5a₁	Mus musculus	C5a-des-Arg	-		3.11	2025-11-26	10.1101/2025.05.26.656101
	9KXS	A	Peptide	Complement Peptide	C5a₁	Mus musculus	EP67	-	Go/β1/γ2	3.31	2025-11-26	10.1101/2025.05.26.656101
	9KXS (No Gprot)	A	Peptide	Complement Peptide	C5a₁	Mus musculus	EP67	-		3.31	2025-11-26	10.1101/2025.05.26.656101
	9UMR	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	C5a-pep	-	Go/β1/γ2	3.15	2025-11-26	10.1101/2025.05.26.656101
	9UMR (No Gprot)	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	C5a-pep	-		3.15	2025-11-26	10.1101/2025.05.26.656101
	9UMX	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	EP54	-	Go/β1/γ2	3.2	2025-11-26	10.1101/2025.05.26.656101
	9UMX (No Gprot)	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	EP54	-		3.2	2025-11-26	10.1101/2025.05.26.656101
	8JZP	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	C5a	-	Go/β1/γ2	3.54	2025-01-15	To be published
	8JZP (No Gprot)	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	C5a	-		3.54	2025-01-15	To be published
	9KUG	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	EP67	-	Go/β1/γ2	3.07	2025-11-26	10.1101/2025.05.26.656101
	9KUG (No Gprot)	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	EP67	-		3.07	2025-11-26	10.1101/2025.05.26.656101

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 7Y67_nogp.zip

You can click to copy the link of this page to easily come back here later

or use this QR code to link and share this page.

You can also read or download a guide explaining the meaning of all files and numerical data.