psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:Y30	9.29	Yes	Yes	1	0	8
2	L:L:?1	R:R:L79	5.49	Yes	No	0	0	6
3	L:L:?1	R:R:Y83	10.45	Yes	No	0	0	5
4	L:L:?1	R:R:R99	8.43	Yes	No	0	0	6
5	L:L:?1	R:R:L102	5.49	Yes	Yes	1	0	7
6	L:L:?1	R:R:H103	7.64	Yes	No	1	0	5
7	L:L:?1	R:R:R281	21.67	Yes	No	1	0	6
8	R:R:N13	R:R:T10	7.31	Yes	No	3	6	9
9	R:R:T10	R:R:W14	10.92	No	Yes	3	9	5
10	R:R:C11	R:R:C268	7.28	No	No	0	7	1
11	R:R:N13	R:R:W14	5.65	Yes	Yes	3	6	5
12	R:R:V272	R:R:W14	11.03	No	Yes	0	3	5
13	R:R:E18	R:R:V271	7.13	No	No	0	5	2
14	R:R:E22	R:R:Y83	7.86	No	No	0	5	5
15	R:R:K23	R:R:Y24	8.36	No	No	0	4	3
16	R:R:F29	R:R:Y25	7.22	No	Yes	1	5	4
17	R:R:V279	R:R:Y25	7.57	No	Yes	0	5	4
18	R:R:P282	R:R:Y25	9.74	No	Yes	1	5	4
19	R:R:L26	R:R:Y30	17.58	No	Yes	0	6	8
20	R:R:L26	R:R:Y83	8.21	No	No	0	6	5
21	R:R:F29	R:R:I32	7.54	No	No	0	5	6
22	R:R:F29	R:R:P282	10.11	No	No	1	5	5
23	R:R:L76	R:R:Y30	4.69	No	Yes	0	8	8
24	R:R:I80	R:R:Y30	4.84	No	Yes	0	6	8
25	R:R:R281	R:R:Y30	5.14	No	Yes	1	6	8
26	R:R:P282	R:R:Y30	6.95	No	Yes	1	5	8
27	R:R:F285	R:R:Y30	8.25	No	Yes	0	7	8
28	R:R:E33	R:R:L286	5.3	No	No	0	7	5
29	R:R:E33	R:R:V289	5.7	No	No	0	7	8
30	R:R:F34	R:R:V38	7.87	No	No	0	7	6
31	R:R:F34	R:R:P77	7.22	No	No	0	7	8
32	R:R:L73	R:R:V38	5.96	No	No	0	6	6
33	R:R:N41	R:R:S66	5.96	No	No	0	9	9
34	R:R:D69	R:R:N41	6.73	Yes	No	0	9	9
35	R:R:N41	R:R:P292	13.03	No	No	0	9	9
36	R:R:V44	R:R:Y48	6.31	No	No	4	9	7
37	R:R:P292	R:R:V44	5.3	No	No	0	9	9
38	R:R:F296	R:R:V44	10.49	Yes	No	4	6	9
39	R:R:S66	R:R:V45	4.85	No	No	0	9	8
40	R:R:Q309	R:R:Y46	5.64	No	No	0	5	4
41	R:R:F296	R:R:Y48	17.54	Yes	No	4	6	7
42	R:R:F63	R:R:W55	10.02	No	No	0	6	6
43	R:R:N56	R:R:N59	8.17	No	No	0	7	7
44	R:R:N56	R:R:R129	14.46	No	Yes	0	7	5
45	R:R:D119	R:R:S58	8.83	No	No	0	8	8
46	R:R:R129	R:R:S58	5.27	Yes	No	0	5	8
47	R:R:A139	R:R:I60	6.5	No	No	0	7	7
48	R:R:I140	R:R:I60	5.89	No	No	0	4	7
49	R:R:F115	R:R:Y61	8.25	No	Yes	5	6	7
50	R:R:D119	R:R:Y61	4.6	No	Yes	0	8	7
51	R:R:I142	R:R:Y61	6.04	No	Yes	5	5	7
52	R:R:I116	R:R:L62	5.71	No	No	0	9	8
53	R:R:F63	R:R:V67	7.87	No	No	0	6	7
54	R:R:F112	R:R:N64	12.08	Yes	No	2	8	9
55	R:R:N64	R:R:S143	5.96	No	No	2	9	7
56	R:R:L113	R:R:L65	5.54	No	No	0	8	9
57	R:R:N105	R:R:S68	5.96	No	Yes	2	8	8
58	R:R:S68	R:R:T108	4.8	Yes	No	2	8	7
59	R:R:S109	R:R:S68	4.89	No	Yes	0	9	8
60	R:R:S68	R:R:W147	4.94	Yes	Yes	2	8	9
61	R:R:D69	R:R:S109	5.89	Yes	No	0	9	9
62	R:R:D69	R:R:S288	11.78	Yes	No	0	9	9
63	R:R:D69	R:R:N291	8.08	Yes	No	0	9	9
64	R:R:A71	R:R:N105	4.69	No	No	0	6	8
65	R:R:F72	R:R:L102	6.09	No	Yes	0	7	7
66	R:R:F72	R:R:L106	4.87	No	No	0	7	8
67	R:R:F285	R:R:F72	13.93	No	No	0	7	7
68	R:R:L102	R:R:T75	5.9	Yes	No	0	7	6
69	R:R:M78	R:R:W88	5.82	No	Yes	0	7	8
70	R:R:M78	R:R:Y90	10.78	No	Yes	0	7	7
71	R:R:M78	R:R:N98	15.43	No	No	0	7	4
72	R:R:L79	R:R:W88	4.56	No	Yes	0	6	8
73	R:R:N85	R:R:R81	14.46	No	No	0	3	5
74	R:R:R81	R:R:Y90	5.14	No	Yes	0	5	7
75	R:R:S82	R:R:W88	9.88	No	Yes	0	5	8
76	R:R:C95	R:R:W88	7.84	No	Yes	0	9	8
77	R:R:C172	R:R:W88	6.53	No	Yes	0	9	8
78	R:R:I89	R:R:Y90	12.09	No	Yes	0	3	7
79	R:R:L94	R:R:Y90	5.86	No	Yes	0	6	7
80	R:R:D92	R:R:P163	11.27	No	No	0	2	5
81	R:R:I161	R:R:I96	8.83	No	No	0	4	7
82	R:R:T151	R:R:Y100	4.99	No	Yes	0	4	6
83	R:R:L154	R:R:Y100	8.21	No	Yes	0	7	6
84	R:R:L155	R:R:Y100	4.69	No	Yes	0	4	6
85	R:R:H103	R:R:L102	6.43	No	Yes	1	5	7
86	R:R:F175	R:R:H103	11.31	Yes	No	0	4	5
87	R:R:N105	R:R:W147	4.52	No	Yes	2	8	9
88	R:R:L106	R:R:Y107	8.21	No	Yes	0	8	7
89	R:R:L191	R:R:Y107	14.07	No	Yes	0	5	7
90	R:R:H249	R:R:Y107	7.62	Yes	Yes	1	8	7
91	R:R:R252	R:R:Y107	6.17	Yes	Yes	1	6	7
92	R:R:T108	R:R:W147	10.92	No	Yes	2	7	9
93	R:R:T108	R:R:V150	6.35	No	No	0	7	8
94	R:R:F241	R:R:I110	6.28	Yes	No	1	9	8
95	R:R:F245	R:R:I110	10.05	Yes	No	1	8	8
96	R:R:I146	R:R:L111	8.56	No	No	0	7	6
97	R:R:F112	R:R:S143	5.28	Yes	No	2	8	7
98	R:R:F112	R:R:I146	17.58	Yes	No	0	8	7
99	R:R:F112	R:R:W147	6.01	Yes	Yes	2	8	9
100	R:R:L113	R:R:Y295	4.69	No	Yes	0	8	9
101	R:R:P199	R:R:T114	5.25	No	No	0	8	7
102	R:R:M203	R:R:T114	4.52	Yes	No	0	8	7
103	R:R:F115	R:R:I142	7.54	No	No	5	6	5
104	R:R:F115	R:R:I146	6.28	No	No	0	6	7
105	R:R:I116	R:R:R120	6.26	No	No	0	9	9
106	R:R:M203	R:R:S117	4.6	Yes	No	1	8	9
107	R:R:S117	R:R:Y207	8.9	No	Yes	1	9	9
108	R:R:F206	R:R:I118	7.54	No	No	0	8	6
109	R:R:R120	R:R:Y207	8.23	No	Yes	0	9	9
110	R:R:R120	R:R:Y295	6.17	No	Yes	0	9	9
111	R:R:F206	R:R:Y121	9.28	No	No	0	8	8
112	R:R:K209	R:R:Y121	14.33	No	No	0	4	8
113	R:R:L122	R:R:Q134	5.32	No	Yes	0	5	7
114	R:R:I123	R:R:R129	11.27	No	Yes	0	8	5
115	R:R:F213	R:R:I124	15.07	No	No	0	5	8
116	R:R:K125	R:R:Y126	14.33	No	Yes	0	7	6
117	R:R:H131	R:R:Y126	16.33	Yes	Yes	7	4	6
118	R:R:Q134	R:R:Y126	5.64	Yes	Yes	7	7	6
119	R:R:E130	R:R:F128	11.66	No	No	0	5	5
120	R:R:Q134	R:R:R129	7.01	Yes	Yes	0	7	5
121	R:R:H131	R:R:L133	6.43	Yes	No	0	4	3
122	R:R:H131	R:R:Q134	4.95	Yes	Yes	7	4	7
123	R:R:F138	R:R:L132	13.4	No	No	0	4	4
124	R:R:I157	R:R:L154	7.14	Yes	No	6	4	7
125	R:R:L154	R:R:Y187	4.69	No	Yes	6	7	5
126	R:R:P156	R:R:Y187	13.91	No	Yes	0	8	5
127	R:R:I157	R:R:I161	7.36	Yes	No	0	4	4
128	R:R:F175	R:R:I157	8.79	Yes	Yes	0	4	4
129	R:R:I157	R:R:Y187	4.84	Yes	Yes	6	4	5
130	R:R:L160	R:R:P159	4.93	No	No	0	5	4
131	R:R:L160	R:R:Y183	7.03	No	No	0	5	2
132	R:R:L160	R:R:N184	5.49	No	No	0	5	3
133	R:R:N173	R:R:S177	7.45	No	No	0	4	4
134	R:R:N173	R:R:S178	5.96	No	No	0	4	3
135	R:R:D174	R:R:S177	5.89	No	No	0	5	4
136	R:R:F175	R:R:R252	5.34	Yes	Yes	0	4	6
137	R:R:A176	R:R:Y277	5.34	No	Yes	0	6	5
138	R:R:R255	R:R:S177	5.27	Yes	No	0	5	4
139	R:R:D180	R:R:P181	8.05	No	No	0	3	1
140	R:R:D180	R:R:N182	12.12	No	No	0	3	1
141	R:R:P181	R:R:R259	12.97	No	No	0	1	3
142	R:R:I256	R:R:N184	12.74	No	No	0	5	3
143	R:R:I256	R:R:L185	5.71	No	No	0	5	4
144	R:R:L191	R:R:Y187	7.03	No	Yes	0	5	5
145	R:R:R252	R:R:S188	9.22	Yes	No	0	6	5
146	R:R:M189	R:R:N253	9.82	No	No	0	5	6
147	R:R:H249	R:R:T192	8.21	Yes	No	1	8	6
148	R:R:R252	R:R:T192	5.17	Yes	No	1	6	6
149	R:R:N253	R:R:T192	7.31	No	No	0	6	6
150	R:R:L193	R:R:L197	5.54	No	No	0	5	4
151	R:R:F196	R:R:L197	4.87	No	No	0	8	4
152	R:R:F196	R:R:T246	9.08	No	No	0	8	5
153	R:R:F196	R:R:H249	22.63	No	Yes	0	8	8
154	R:R:F241	R:R:L200	4.87	Yes	No	0	9	6
155	R:R:M203	R:R:Y207	4.79	Yes	Yes	1	8	9
156	R:R:F241	R:R:M203	11.2	Yes	Yes	1	9	8
157	R:R:F205	R:R:F206	9.65	No	No	0	4	8
158	R:R:F205	R:R:K209	6.2	No	No	0	4	4
159	R:R:V234	R:R:Y207	7.57	No	Yes	0	8	9
160	R:R:L212	R:R:Y208	14.07	No	No	0	3	3
161	R:R:I210	R:R:V234	4.61	No	No	0	8	8
162	R:R:F213	R:R:R217	8.55	No	No	0	5	5
163	R:R:K215	R:R:L231	7.05	No	Yes	0	4	6
164	R:R:Q220	R:R:R217	5.84	No	No	0	2	5
165	R:R:N218	R:R:P226	4.89	No	Yes	0	4	5
166	R:R:P226	R:R:R219	12.97	Yes	No	0	5	4
167	R:R:E228	R:R:P226	9.43	No	Yes	0	5	5
168	R:R:L227	R:R:P230	4.93	No	No	0	6	7
169	R:R:F294	R:R:M236	4.98	Yes	No	0	7	5
170	R:R:I240	R:R:I290	5.89	No	No	0	7	6
171	R:R:F294	R:R:I240	5.02	Yes	No	0	7	7
172	R:R:F241	R:R:F245	7.5	Yes	Yes	1	9	8
173	R:R:L244	R:R:L286	5.54	No	No	0	9	5
174	R:R:L244	R:R:N287	12.36	No	No	0	9	9
175	R:R:F245	R:R:H249	4.53	Yes	Yes	1	8	8
176	R:R:F245	R:R:N287	13.29	Yes	No	0	8	9
177	R:R:H249	R:R:Y248	11.98	Yes	Yes	1	8	7
178	R:R:R252	R:R:Y248	9.26	Yes	Yes	1	6	7
179	R:R:Y248	R:R:Y277	6.95	Yes	Yes	1	7	5
180	R:R:A284	R:R:Y248	5.34	No	Yes	0	8	7
181	R:R:H249	R:R:R252	6.77	Yes	Yes	1	8	6
182	R:R:F276	R:R:M251	4.98	No	No	0	5	4
183	R:R:M251	R:R:T280	4.52	No	No	0	4	7
184	R:R:R252	R:R:Y277	9.26	Yes	Yes	1	6	5
185	R:R:N274	R:R:R255	19.28	No	Yes	0	3	5
186	R:R:R255	R:R:Y277	7.2	Yes	Yes	0	5	5
187	R:R:Q270	R:R:S258	5.78	No	No	0	3	2
188	R:R:I273	R:R:S258	4.64	No	No	0	5	2
189	R:R:R281	R:R:Y277	14.4	No	Yes	1	6	5
190	R:R:N287	R:R:N291	5.45	No	No	0	9	9
191	R:R:N291	R:R:Y295	5.81	No	Yes	0	9	9
192	R:R:F294	R:R:Y295	9.28	Yes	Yes	0	7	9
193	R:R:F296	R:R:F302	12.86	Yes	No	0	6	8
194	R:R:F296	R:R:L306	4.87	Yes	No	0	6	7
195	R:R:D300	R:R:R303	7.15	No	No	0	5	8
196	R:R:H301	R:R:M305	6.57	No	No	0	6	4
197	R:R:L73	R:R:S288	4.5	No	No	0	6	9
198	R:R:L70	R:R:V38	4.47	No	No	0	8	6
199	R:R:I124	R:R:I210	4.42	No	No	0	8	8
200	R:R:I60	R:R:K136	4.36	No	No	0	7	1
201	R:R:I278	R:R:N274	4.25	No	No	0	4	3
202	R:R:K229	R:R:L233	4.23	No	No	0	7	8
203	R:R:L233	R:R:L298	4.15	No	No	0	8	6
204	R:R:L260	R:R:N182	4.12	No	No	0	1	1
205	R:R:A139	R:R:Y61	4	No	Yes	0	7	7
206	R:R:A237	R:R:Y207	4	No	Yes	0	8	9
207	R:R:E153	R:R:L191	3.98	No	No	0	5	5
208	R:R:E153	R:R:L194	3.98	No	No	0	5	5
209	R:R:E18	R:R:N274	3.94	No	No	0	5	3
210	R:R:V238	R:R:Y207	3.79	No	Yes	0	8	9
211	R:R:C95	R:R:P163	3.77	No	No	0	9	5
212	R:R:F138	R:R:K135	3.72	No	No	0	4	6
213	R:R:G179	R:R:S178	3.71	No	No	0	1	3
214	R:R:G37	R:R:V36	3.68	No	No	0	8	6
215	R:R:G37	R:R:V289	3.68	No	No	0	8	8
216	R:R:F201	R:R:L200	3.65	No	No	0	3	6
217	R:R:F294	R:R:L233	3.65	Yes	No	0	7	8
218	R:R:I210	R:R:Y121	3.63	No	No	0	8	8
219	R:R:F175	R:R:N184	3.62	Yes	No	0	4	3
220	R:R:G40	R:R:I43	3.53	No	No	0	8	6
221	R:R:L21	R:R:Y25	3.52	No	Yes	0	4	4
222	R:R:P247	R:R:T280	3.5	No	No	0	9	7
223	R:R:Q270	R:R:R255	3.5	No	Yes	0	3	5
224	R:R:Q270	R:R:R259	3.5	No	No	0	3	3
225	R:R:G261	R:R:L260	3.42	No	No	0	2	1
226	R:R:I198	R:R:P199	3.39	No	No	0	6	8
227	R:R:E130	R:R:Y126	3.37	No	Yes	0	5	6
228	R:R:K229	R:R:P230	3.35	No	No	0	7	7
229	R:R:L214	R:R:P230	3.28	No	No	0	7	7
230	R:R:L225	R:R:P226	3.28	No	Yes	0	3	5
231	R:R:N162	R:R:P163	3.26	No	No	0	4	5
232	R:R:S242	R:R:T246	3.2	No	No	0	6	5
233	R:R:T75	R:R:V101	3.17	No	No	0	6	5
234	R:R:T114	R:R:V202	3.17	No	No	0	7	7
235	R:R:T171	R:R:V164	3.17	No	No	0	3	1
236	R:R:C204	R:R:L200	3.17	No	No	0	5	6
237	R:R:F63	R:R:Y48	3.09	No	No	0	6	7
238	R:R:M251	R:R:V254	3.04	No	No	0	4	5
239	R:R:F296	R:R:G47	3.01	Yes	No	0	6	7
240	R:R:L152	R:R:V148	2.98	No	No	0	4	5
241	R:R:L297	R:R:V293	2.98	No	No	0	7	6
242	R:R:L70	R:R:T42	2.95	No	No	0	8	4
243	R:R:D119	R:R:S57	2.94	No	No	0	8	6
244	R:R:G47	R:R:Y46	2.9	No	No	0	7	4
245	R:R:G195	R:R:Y107	2.9	No	Yes	0	6	7
246	R:R:F128	R:R:P127	2.89	No	No	0	5	8
247	R:R:I140	R:R:L144	2.85	No	No	0	4	4
248	R:R:I142	R:R:L141	2.85	No	No	0	5	2
249	R:R:I235	R:R:L231	2.85	No	Yes	0	4	6
250	R:R:A84	R:R:R81	2.77	No	No	0	5	5
251	R:R:L155	R:R:L158	2.77	No	No	0	4	4
252	R:R:L227	R:R:N218	2.75	No	No	0	6	4
253	R:R:A104	R:R:Y100	2.67	No	Yes	0	5	6
254	R:R:L212	R:R:Q216	2.66	No	No	0	3	5
255	R:R:C268	R:R:W14	2.61	No	Yes	0	1	5
256	R:R:T280	R:R:Y248	2.5	No	Yes	0	7	7
257	R:R:V271	R:R:W14	2.45	No	Yes	0	2	5
258	R:R:F296	R:R:L297	2.44	Yes	No	0	6	7
259	R:R:I186	R:R:Y183	2.42	No	No	0	4	2
260	R:R:F302	R:R:H301	2.26	No	No	0	8	6
261	R:R:G40	R:R:P292	2.03	No	No	0	8	9
262	R:R:G31	R:R:I80	1.76	No	No	0	5	6
263	R:R:G86	R:R:K23	1.74	No	No	0	4	4
264	R:R:A84	R:R:S27	1.71	No	No	0	5	5
265	R:R:G40	R:R:L39	1.71	No	No	0	8	4
266	R:R:A224	R:R:V221	1.7	No	No	0	2	3
267	R:R:D92	R:R:G91	1.68	No	No	0	2	8
268	R:R:S97	R:R:V93	1.62	No	No	0	5	2
269	R:R:S275	R:R:V272	1.62	No	No	0	1	3
270	R:R:V239	R:R:V243	1.6	No	No	0	5	6
271	R:R:T246	R:R:V250	1.59	No	No	0	5	7
272	R:R:T269	R:R:V272	1.59	No	No	0	1	3
273	R:R:A145	R:R:L149	1.58	No	No	0	3	4
274	R:R:A257	R:R:L185	1.58	No	No	0	4	4
275	R:R:A211	R:R:L231	1.58	No	Yes	0	5	6
276	R:R:A17	R:R:N13	1.56	No	Yes	0	2	6
277	R:R:I235	R:R:V239	1.54	No	No	0	4	5
278	R:R:L39	R:R:V35	1.49	No	No	0	4	4
279	R:R:L94	R:R:V93	1.49	No	No	0	6	2
280	R:R:I89	R:R:N87	1.42	No	No	0	3	4
281	R:R:K12	R:R:N13	1.4	No	Yes	0	4	6
282	R:R:L214	R:R:L231	1.38	No	Yes	0	7	6
283	R:R:D300	R:R:K229	1.38	No	No	0	5	7
284	R:R:L244	R:R:L283	1.38	No	No	0	9	7
285	R:R:E137	R:R:K135	1.35	No	No	0	3	6
286	R:R:H131	R:R:L132	1.29	Yes	No	0	4	4
287	R:R:I28	R:R:Y24	1.21	No	No	0	6	3
288	R:R:I49	R:R:W55	1.17	No	No	0	4	6

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:?1	9.78	7	1	0
2	R:R:N13	3.98	4	3	6
3	R:R:W14	6.532	5	3	5
4	R:R:Y25	7.0125	4	1	4
5	R:R:Y30	8.10571	7	1	8
6	R:R:Y61	5.7225	4	5	7
7	R:R:S68	5.1475	4	2	8
8	R:R:D69	8.12	4	0	9
9	R:R:W88	6.926	5	0	8
10	R:R:Y90	8.4675	4	0	7
11	R:R:Y100	5.14	4	0	6
12	R:R:L102	5.9775	4	1	7
13	R:R:Y107	7.794	5	1	7
14	R:R:F112	10.2375	4	2	8
15	R:R:Y126	9.9175	4	7	6
16	R:R:R129	9.5025	4	0	5
17	R:R:H131	7.25	4	7	4
18	R:R:Q134	5.73	4	7	7
19	R:R:W147	6.5975	4	2	9
20	R:R:I157	7.0325	4	6	4
21	R:R:F175	7.265	4	0	4
22	R:R:Y187	7.6175	4	6	5
23	R:R:M203	6.2775	4	1	8
24	R:R:Y207	6.21333	6	1	9
25	R:R:P226	7.6425	4	0	5
26	R:R:L231	3.215	4	0	6
27	R:R:F241	7.4625	4	1	9
28	R:R:F245	8.8425	4	1	8
29	R:R:Y248	7.206	5	1	7
30	R:R:H249	10.29	6	1	8
31	R:R:R252	7.31286	7	1	6
32	R:R:R255	8.8125	4	0	5
33	R:R:Y277	8.63	5	1	5
34	R:R:F294	5.7325	4	0	7
35	R:R:Y295	6.4875	4	0	9
36	R:R:F296	8.535	6	4	6

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:R281	28.2305	21.67	Yes	No	1	0	6
2	R:R:R281	R:R:Y277	41.6403	14.4	No	Yes	1	6	5
3	R:R:R255	R:R:Y277	35.6861	7.2	Yes	Yes	0	5	5
4	R:R:N274	R:R:R255	17.9367	19.28	No	Yes	0	3	5
5	R:R:E18	R:R:N274	15.4343	3.94	No	No	0	5	3
6	R:R:E18	R:R:V271	14.2686	7.13	No	No	0	5	2
7	R:R:V271	R:R:W14	12.9997	2.45	No	Yes	0	2	5
8	L:L:?1	R:R:H103	15.5796	7.64	Yes	No	1	0	5
9	R:R:F175	R:R:H103	17.9367	11.31	Yes	No	0	4	5
10	R:R:F175	R:R:R252	26.4159	5.34	Yes	Yes	0	4	6
11	R:R:H249	R:R:R252	55.5538	6.77	Yes	Yes	1	8	6
12	R:R:F245	R:R:H249	100	4.53	Yes	Yes	1	8	8
13	R:R:F245	R:R:N287	82.5541	13.29	Yes	No	0	8	9
14	R:R:R252	R:R:Y277	37.0165	9.26	Yes	Yes	1	6	5
15	R:R:Y248	R:R:Y277	33.8618	6.95	Yes	Yes	1	7	5
16	R:R:H249	R:R:Y248	35.8508	11.98	Yes	Yes	1	8	7
17	R:R:N287	R:R:N291	79.196	5.45	No	No	0	9	9
18	R:R:D69	R:R:N291	68.35	8.08	Yes	No	0	9	9
19	R:R:D69	R:R:N41	26.1769	6.73	Yes	No	0	9	9
20	R:R:N41	R:R:P292	23.0869	13.03	No	No	0	9	9
21	R:R:P292	R:R:V44	17.8076	5.3	No	No	0	9	9
22	R:R:F296	R:R:V44	11.0978	10.49	Yes	No	4	6	9
23	R:R:D69	R:R:S109	42.6736	5.89	Yes	No	0	9	9
24	R:R:S109	R:R:S68	41.7598	4.89	No	Yes	0	9	8
25	R:R:S68	R:R:W147	36.6419	4.94	Yes	Yes	2	8	9
26	R:R:F112	R:R:W147	36.1414	6.01	Yes	Yes	2	8	9
27	R:R:F112	R:R:I146	33.2451	17.58	Yes	No	0	8	7
28	R:R:F115	R:R:I146	31.2787	6.28	No	No	0	6	7
29	R:R:F115	R:R:Y61	28.1208	8.25	No	Yes	5	6	7
30	R:R:D119	R:R:Y61	22.1214	4.6	No	Yes	0	8	7
31	R:R:D119	R:R:S58	20.0194	8.83	No	No	0	8	8
32	R:R:R129	R:R:S58	18.9506	5.27	Yes	No	0	5	8
33	R:R:F241	R:R:F245	23.0772	7.5	Yes	Yes	1	9	8
34	R:R:F241	R:R:M203	19.5383	11.2	Yes	Yes	1	9	8
35	R:R:M203	R:R:Y207	15.6958	4.79	Yes	Yes	1	8	9
36	R:R:N291	R:R:Y295	33.9264	5.81	No	Yes	0	9	9
37	R:R:R120	R:R:Y295	10.5747	6.17	No	Yes	0	9	9
38	L:L:?1	R:R:L79	37.4265	5.49	Yes	No	0	0	6
39	R:R:L79	R:R:W88	35.8379	4.56	No	Yes	0	6	8
40	R:R:M78	R:R:W88	21.8114	5.82	No	Yes	0	7	8
41	R:R:M78	R:R:Y90	18.2402	10.78	No	Yes	0	7	7
42	R:R:V234	R:R:Y207	13.6907	7.57	No	Yes	0	8	9
43	R:R:I210	R:R:V234	12.5767	4.61	No	No	0	8	8
44	R:R:Q134	R:R:R129	14.6367	7.01	Yes	Yes	0	7	5
45	R:R:Q270	R:R:R255	11.6371	3.5	No	Yes	0	3	5
46	R:R:F294	R:R:Y295	24.9112	9.28	Yes	Yes	0	7	9
47	R:R:F294	R:R:L233	20.8298	3.65	Yes	No	0	7	8
48	R:R:K229	R:R:L233	18.7956	4.23	No	No	0	7	8
49	R:R:K229	R:R:P230	15.6539	3.35	No	No	0	7	7
50	R:R:R281	R:R:Y30	12.4152	5.14	No	Yes	1	6	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?1	R:R:Y30	9.29	1	Yes	Yes	0	8	0	1
L:L:?1	R:R:L79	5.49	1	Yes	No	0	6	0	1
L:L:?1	R:R:Y83	10.45	1	Yes	No	0	5	0	1
L:L:?1	R:R:R99	8.43	1	Yes	No	0	6	0	1
L:L:?1	R:R:L102	5.49	1	Yes	Yes	0	7	0	1
L:L:?1	R:R:H103	7.64	1	Yes	No	0	5	0	1
L:L:?1	R:R:R281	21.67	1	Yes	No	0	6	0	1
R:R:E22	R:R:Y83	7.86	0	No	No	5	5	2	1
R:R:L26	R:R:Y30	17.58	0	No	Yes	6	8	2	1
R:R:L26	R:R:Y83	8.21	0	No	No	6	5	2	1
R:R:L76	R:R:Y30	4.69	0	No	Yes	8	8	2	1
R:R:I80	R:R:Y30	4.84	0	No	Yes	6	8	2	1
R:R:R281	R:R:Y30	5.14	1	No	Yes	6	8	1	1
R:R:P282	R:R:Y30	6.95	1	No	Yes	5	8	2	1
R:R:F285	R:R:Y30	8.25	0	No	Yes	7	8	2	1
R:R:F72	R:R:L102	6.09	0	No	Yes	7	7	2	1
R:R:F285	R:R:F72	13.93	0	No	No	7	7	2	2
R:R:L102	R:R:T75	5.9	1	Yes	No	7	6	1	2
R:R:L79	R:R:W88	4.56	0	No	Yes	6	8	1	2
R:R:H103	R:R:L102	6.43	1	No	Yes	5	7	1	1
R:R:F175	R:R:H103	11.31	0	Yes	No	4	5	2	1
R:R:R281	R:R:Y277	14.4	1	No	Yes	6	5	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	8YKW_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	4.51
Number of Linked Nodes	271
Number of Links	288
Number of Hubs	36
Number of Links mediated by Hubs	139
Number of Communities	7
Number of Nodes involved in Communities	42
Number of Links involved in Communities	52

Path Summary
Number Of Nodes in MetaPath	51
Number Of Links MetaPath	50
Number of Shortest Paths	49333
Length Of Smallest Path	3
Average Path Length	13.9386
Length of Longest Path	32
Minimum Path Strength	1.48
Average Path Strength	7.4799
Maximum Path Strength	18.035
Minimum Path Correlation	0.7
Average Path Correlation	0.930903
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	4
Average % Of Corr. Nodes	50.4647
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	46.4095
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• D2 dopamine receptor binding • protein binding • binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • phosphorus-oxygen lyase activity • enzyme regulator activity • cyclase regulator activity • molecular function regulator activity • cyclase activity • adenylate cyclase regulator activity • lyase activity • catalytic activity • adenylate cyclase activity • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • cation binding • magnesium ion binding • metal ion binding • GDP binding • G protein-coupled serotonin receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • cell communication • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction
Gene Ontology	Biological Process	• cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • cell communication • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • response to hormone • response to chemical • response to endogenous stimulus • response to peptide hormone • response to oxygen-containing compound • response to nitrogen compound • cell division • leukocyte migration • immune system process • mononuclear cell migration • lymphocyte migration • cell migration • T cell migration • cell motility • regulation of steroid biosynthetic process • regulation of cholesterol biosynthetic process • regulation of cholesterol metabolic process • steroid metabolic process • regulation of lipid metabolic process • sterol metabolic process • positive regulation of biological process • cholesterol metabolic process • lipid biosynthetic process • alcohol metabolic process • regulation of primary metabolic process • positive regulation of metabolic process • regulation of small molecule metabolic process • positive regulation of biosynthetic process • positive regulation of lipid metabolic process • small molecule metabolic process • steroid biosynthetic process • positive regulation of cellular process • regulation of biosynthetic process • secondary alcohol biosynthetic process • regulation of alcohol biosynthetic process • small molecule biosynthetic process • regulation of steroid metabolic process • cholesterol biosynthetic process • positive regulation of cholesterol biosynthetic process • primary metabolic process • secondary alcohol metabolic process • positive regulation of steroid biosynthetic process • biosynthetic process • sterol biosynthetic process • positive regulation of lipid biosynthetic process • regulation of sterol biosynthetic process • alcohol biosynthetic process • positive regulation of cholesterol metabolic process • positive regulation of steroid metabolic process • metabolic process • regulation of lipid biosynthetic process • positive regulation of small molecule metabolic process • regulation of metabolic process • positive regulation of alcohol biosynthetic process • positive regulation of sterol biosynthetic process • lipid metabolic process • regulation of cytoskeleton organization • regulation of cellular component organization • microtubule cytoskeleton organization • regulation of mitotic spindle organization • mitotic cell cycle • cellular component organization • cell cycle • cellular component organization or biogenesis • regulation of cell cycle • microtubule cytoskeleton organization involved in mitosis • spindle organization • cell cycle process • regulation of cell cycle process • regulation of microtubule-based process • regulation of spindle organization • regulation of organelle organization • mitotic spindle organization • organelle organization • mitotic cell cycle process • microtubule-based process • cytoskeleton organization • regulation of microtubule cytoskeleton organization • protein localization • positive regulation of protein localization to cell periphery • regulation of localization • protein localization to cell periphery • cellular localization • regulation of protein localization • positive regulation of protein localization to cell cortex • regulation of protein localization to cell periphery • localization • regulation of cellular localization • regulation of protein localization to cell cortex • cellular macromolecule localization • macromolecule localization • positive regulation of protein localization • protein localization to cell cortex • response to ketone • response to prostaglandin • response to lipid • response to alcohol • response to prostaglandin E • cellular response to forskolin • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to alcohol • response to forskolin • cellular response to lipid • cellular response to ketone • midbody • cellular anatomical structure • membrane-bounded organelle • intracellular anatomical structure • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • intracellular membrane-bounded organelle • nucleolus • intracellular organelle lumen • intracellular organelle • organelle lumen • organelle • membraneless organelle
Gene Ontology	Cellular Component	• midbody • cellular anatomical structure • membrane-bounded organelle • intracellular anatomical structure • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • intracellular membrane-bounded organelle • nucleolus • intracellular organelle lumen • intracellular organelle • organelle lumen • organelle • membraneless organelle • nuclear lumen • cell periphery • cell cortex • cytoplasm • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular region • extracellular space • vesicle • extracellular membrane-bounded organelle • centrosome • microtubule organizing center • cytoskeleton • microtubule cytoskeleton • centriolar satellite • cytosol • nucleoplasm • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • organelle membrane • lysosome • Golgi apparatus • endomembrane system • cilium • plasma membrane bounded cell projection • ciliary basal body • cell projection • cytoskeletal protein binding • spectrin binding • protein-containing complex binding • protein binding • binding • enzyme binding • GTPase binding • phosphoric ester hydrolase activity • alkylglycerophosphoethanolamine phosphodiesterase activity • hydrolase activity, acting on ester bonds • phosphoric diester hydrolase activity • hydrolase activity • catalytic activity • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity, acting on acid anhydrides • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • positive regulation of cytosolic calcium ion concentration • biological regulation • regulation of biological quality • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • response to decreased oxygen levels • cellular response to stimulus • response to stimulus • cellular response to oxygen levels • cellular response to hypoxia • cellular response to decreased oxygen levels • cellular response to chemical stimulus • cellular response to stress • response to hypoxia • response to stress • response to chemical • response to oxygen levels • response to abiotic stimulus • cellular process • cell population proliferation • regulation of biological process • regulation of cellular process • signaling • phospholipase C-activating G protein-coupled receptor signaling pathway • cell communication • G protein-coupled receptor signaling pathway • signal transduction • muscle cell apoptotic process • striated muscle cell apoptotic process • apoptotic process • cell death • programmed cell death • cardiac muscle cell apoptotic process • photoreceptor inner segment • somatodendritic compartment • dendrite • dendritic tree • neuron projection • non-motile cilium • 9+0 non-motile cilium • photoreceptor outer segment • photoreceptor cell cilium • ciliary membrane • photoreceptor outer segment membrane • plasma membrane region • cell projection membrane • synapse • cell junction • cell body • G-protein beta-subunit binding • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to oxygen-containing compound • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to oxygen-containing compound • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • response to hormone • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • molecular transducer activity • signaling receptor activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • macrophage activation involved in immune response • immune response • cell activation • cell activation involved in immune response • myeloid cell activation involved in immune response • myeloid leukocyte activation • leukocyte activation • immune effector process • macrophage activation • immune system process • leukocyte activation involved in immune response • regulation of defense response • regulation of response to external stimulus • defense response • positive regulation of biological process • response to external stimulus • regulation of inflammatory response • positive regulation of response to stimulus • positive regulation of response to external stimulus • positive regulation of inflammatory response • regulation of response to stimulus • regulation of response to stress • positive regulation of defense response • inflammatory response • response to metal ion • response to calcium ion • chemotaxis • positive regulation of locomotion • regulation of chemotaxis • positive regulation of chemotaxis • taxis • regulation of locomotion • locomotion • regulation of systemic arterial blood pressure by renin-angiotensin • protein localization • renin secretion into blood stream • regulation of systemic arterial blood pressure by hormone • regulation of systemic arterial blood pressure mediated by a chemical signal • establishment of protein localization • cellular localization • nitrogen compound transport • transport • protein localization to extracellular region • localization • secretion by cell • circulatory system process • renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure • signal release • cellular macromolecule localization • renal system process involved in regulation of systemic arterial blood pressure • blood circulation • renal system process • secretion • regulation of blood pressure • establishment of protein localization to extracellular region • cell-cell signaling • export from cell • regulation of systemic arterial blood pressure by circulatory renin-angiotensin • protein secretion • establishment of localization • regulation of systemic arterial blood pressure • endocrine process • protein transport • macromolecule localization • regulation of protein metabolic process • primary metabolic process • regulation of macromolecule metabolic process • regulation of primary metabolic process • regulation of angiotensin metabolic process • metabolic process • protein metabolic process • macromolecule metabolic process • regulation of metabolic process • multicellular organismal-level homeostasis • homeostatic process • energy homeostasis • chemical homeostasis • glucose homeostasis • carbohydrate homeostasis
SCOP2	Domain Identifier	• Ras-like P-loop GTPases • Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Ras-like P-loop GTPases • Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	SIN
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	SIN
Name	Succinic acid
Synonyms	Acidum succinicum
Identifier
Formula	C4 H6 O4
Molecular Weight	118.088
SMILES
PubChem	21952380
Formal Charge	0
Total Atoms	14
Total Chiral Atoms	0
Total Bonds	13
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q9BXA5
Sequence	>8YKW_nogp_Chain_R T C K N W L A A E A A L E K Y Y L S I F Y G I E F V V G V L G N T I V V Y G Y I W N S S N I Y L F N L S V S D L A F L C T L P M L I R S Y A N G N W I Y G D V L C I S N R Y V L H A N L Y T S I L F L T F I S I D R Y L I I K Y P F R E H L L Q K K E F A I L I S L A I W V L V T L E L L P I L P L I N P V T C N D F A S S G D P N Y N L I Y S M C L T L L G F L I P L F V M C F F Y Y K I A L F L K Q R N R Q V A T A L P L E K P L N L V I M A V V I F S V L F T P Y H V M R N V R I A S R L G S C T Q V V I N S F Y I V T R P L A F L N S V I N P V F Y F L L G D H F R D M L M N Q Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8WP1	A	Alicarboxylic acid	Succinate	Succinate	Homo sapiens	Cis-Epoxysuccinic acid	-	Gi1/β1/γ2	3.15	2024-09-11	doi.org/10.1016/j.celrep.2024.114381
	8WP1 (No Gprot)	A	Alicarboxylic acid	Succinate	Succinate	Homo sapiens	Cis-Epoxysuccinic acid	-		3.15	2024-09-11	doi.org/10.1016/j.celrep.2024.114381
	8WOG	A	Alicarboxylic acid	Succinate	Succinate	Homo sapiens	Succinic acid	-	Gi1/β1/γ2	2.97	2024-09-11	doi.org/10.1016/j.celrep.2024.114381
	8WOG (No Gprot)	A	Alicarboxylic acid	Succinate	Succinate	Homo sapiens	Succinic acid	-		2.97	2024-09-11	doi.org/10.1016/j.celrep.2024.114381
	8YKX	A	Alicarboxylic acid	Succinate	Succinate	Homo sapiens	Maleic acid	-	Gi1/β1/γ1	2.69	2024-05-29	10.1038/s41422-024-00984-7
	8YKX (No Gprot)	A	Alicarboxylic acid	Succinate	Succinate	Homo sapiens	Maleic acid	-		2.69	2024-05-29	10.1038/s41422-024-00984-7
	8YKW	A	Alicarboxylic acid	Succinate	Succinate	Homo sapiens	Succinic acid	-	Gi1/β1/γ1	2.75	2024-05-29	10.1038/s41422-024-00984-7
	8YKW (No Gprot)	A	Alicarboxylic acid	Succinate	Succinate	Homo sapiens	Succinic acid	-		2.75	2024-05-29	10.1038/s41422-024-00984-7
	8YKV	A	Alicarboxylic acid	Succinate	Succinate	Homo sapiens	PubChem 137553168	-	Gi1/β1/γ2	2.48	2024-05-29	doi.org/10.1038/s41422-024-00984-7
	8YKV (No Gprot)	A	Alicarboxylic acid	Succinate	Succinate	Homo sapiens	PubChem 137553168	-		2.48	2024-05-29	doi.org/10.1038/s41422-024-00984-7
	8JPP	A	Alicarboxylic acid	Succinate	Succinate	Homo sapiens	Succinic acid	-	chim(Gs-CtGq)/β1/γ1	3.2	2024-05-22	10.1038/s41422-024-00968-7
	8JPP (No Gprot)	A	Alicarboxylic acid	Succinate	Succinate	Homo sapiens	Succinic acid	-		3.2	2024-05-22	10.1038/s41422-024-00968-7
	8JPN	A	Alicarboxylic acid	Succinate	Succinate	Homo sapiens	Cis-Epoxysuccinic acid	-	Gi1/β1/γ1	2.9	2024-05-22	10.1038/s41422-024-00968-7
	8JPN (No Gprot)	A	Alicarboxylic acid	Succinate	Succinate	Homo sapiens	Cis-Epoxysuccinic acid	-		2.9	2024-05-22	10.1038/s41422-024-00968-7
	6Z10	A	Alicarboxylic acid	Succinate	Succinate	Rattus norvegicus	PubChem 154585554	-	-	2.27	2020-09-16	10.1021/acs.jmedchem.0c01020
	6RNK	A	Alicarboxylic acid	Succinate	Succinate	Rattus norvegicus	NF-56-EJ40	-	-	1.94	2019-08-14	10.1038/s41586-019-1663-8
	6IBB	A	Alicarboxylic acid	Succinate	Succinate	Rattus norvegicus	-	-	-	2.12	2019-08-14	10.1038/s41586-019-1663-8

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