psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:C13	R:R:C258	7.28	No	No	0	7	5
2	R:R:E166	R:R:T14	5.64	No	No	0	3	3
3	R:R:I15	R:R:Y176	7.25	Yes	Yes	1	2	6
4	R:R:I15	R:R:K262	4.36	Yes	No	0	2	3
5	R:R:F265	R:R:I15	8.79	Yes	Yes	1	3	2
6	R:R:D16	R:R:T18	7.23	No	No	0	3	3
7	R:R:H17	R:R:Q21	3.71	No	No	1	4	4
8	R:R:D85	R:R:H17	22.69	Yes	No	1	4	4
9	R:R:I19	R:R:T22	4.56	No	No	0	3	3
10	R:R:I19	R:R:N266	15.58	No	No	0	3	1
11	R:R:H20	R:R:V81	6.92	Yes	No	0	4	5
12	R:R:D85	R:R:H20	15.13	Yes	Yes	1	4	4
13	R:R:F265	R:R:H20	6.79	Yes	Yes	1	3	4
14	R:R:H20	R:R:H269	22.69	Yes	No	1	4	4
15	R:R:D85	R:R:Q21	9.14	Yes	No	1	4	4
16	R:R:F270	R:R:L23	3.65	No	No	0	6	5
17	R:R:L23	R:R:L273	4.15	No	No	0	5	5
18	R:R:A24	R:R:Y28	4	No	Yes	0	5	8
19	R:R:L273	R:R:V27	11.92	No	No	0	5	5
20	R:R:F277	R:R:V27	7.87	No	No	0	4	5
21	R:R:L78	R:R:Y28	5.86	No	Yes	0	7	8
22	R:R:V81	R:R:Y28	3.79	No	Yes	0	5	8
23	R:R:L273	R:R:Y28	5.86	No	Yes	0	5	8
24	R:R:F277	R:R:V31	3.93	No	No	0	4	7
25	R:R:V280	R:R:V31	4.81	No	No	0	7	7
26	R:R:L32	R:R:L74	4.15	No	No	6	6	7
27	R:R:G35	R:R:V34	3.68	No	No	5	8	6
28	R:R:V280	R:R:V34	6.41	No	No	5	7	6
29	R:R:G35	R:R:V280	3.68	No	No	5	8	7
30	R:R:F36	R:R:P37	4.33	No	No	0	6	5
31	R:R:C40	R:R:F36	5.59	No	No	0	3	6
32	R:R:A38	R:R:P283	3.74	No	No	0	7	9
33	R:R:N39	R:R:T64	4.39	Yes	No	0	9	8
34	R:R:D67	R:R:N39	4.04	Yes	Yes	0	9	9
35	R:R:L68	R:R:N39	8.24	No	Yes	0	7	9
36	R:R:N39	R:R:P283	4.89	Yes	No	0	9	9
37	R:R:F288	R:R:L41	3.65	Yes	No	0	7	6
38	R:R:L43	R:R:T64	5.9	No	No	0	6	8
39	R:R:F45	R:R:Y44	13.41	No	No	0	6	4
40	R:R:L48	R:R:Y44	10.55	No	No	0	4	4
41	R:R:C287	R:R:F45	6.98	No	No	0	6	6
42	R:R:F45	R:R:T293	12.97	No	No	0	6	8
43	R:R:K51	R:R:L48	5.64	No	No	0	6	4
44	R:R:N54	R:R:Q49	3.96	No	No	0	7	4
45	R:R:L135	R:R:R53	7.29	No	No	0	3	5
46	R:R:L56	R:R:N54	5.49	No	No	0	7	7
47	R:R:E55	R:R:L135	3.98	No	No	0	6	3
48	R:R:L56	R:R:L60	5.54	No	No	0	7	7
49	R:R:A138	R:R:V58	5.09	No	No	0	7	6
50	R:R:C114	R:R:Y59	9.41	No	Yes	0	6	7
51	R:R:D118	R:R:Y59	6.9	No	Yes	0	8	7
52	R:R:A138	R:R:Y59	4	No	Yes	0	7	7
53	R:R:V141	R:R:Y59	3.79	No	Yes	0	4	7
54	R:R:I115	R:R:L60	5.71	No	No	0	8	7
55	R:R:F111	R:R:N62	9.67	Yes	No	3	7	9
56	R:R:N62	R:R:S142	8.94	No	No	3	9	6
57	R:R:N62	R:R:W146	5.65	No	Yes	3	9	9
58	R:R:D67	R:R:L63	4.07	Yes	No	0	9	9
59	R:R:F111	R:R:L63	3.65	Yes	No	0	7	9
60	R:R:L112	R:R:L63	5.54	No	No	0	8	9
61	R:R:A66	R:R:N104	4.69	No	No	0	8	8
62	R:R:D67	R:R:S108	5.89	Yes	No	0	9	9
63	R:R:C279	R:R:D67	6.22	No	Yes	0	8	9
64	R:R:D282	R:R:D67	7.98	No	Yes	0	9	9
65	R:R:L101	R:R:Y70	4.69	No	No	0	6	6
66	R:R:S276	R:R:Y70	3.82	No	No	0	7	6
67	R:R:C279	R:R:Y70	5.38	No	No	0	8	6
68	R:R:C279	R:R:I71	4.91	No	No	0	8	5
69	R:R:L100	R:R:S73	6.01	No	No	0	5	6
70	R:R:C97	R:R:F76	5.59	No	No	0	5	6
71	R:R:W77	R:R:Y80	4.82	Yes	No	1	6	5
72	R:R:W77	R:R:W87	7.5	Yes	Yes	1	6	9
73	R:R:L101	R:R:W77	9.11	No	Yes	1	6	6
74	R:R:W77	R:R:Y102	6.75	Yes	Yes	1	6	5
75	R:R:Q79	R:R:Q83	8.96	No	No	7	4	4
76	R:R:Q79	R:R:S88	4.33	No	No	7	4	3
77	R:R:D85	R:R:Y80	11.49	Yes	No	1	4	5
78	R:R:W87	R:R:Y80	10.61	Yes	No	1	9	5
79	R:R:N86	R:R:Q83	5.28	No	No	0	4	4
80	R:R:Q83	R:R:S88	8.66	No	No	7	4	3
81	R:R:H169	R:R:N86	14.03	No	No	0	2	4
82	R:R:C94	R:R:W87	7.84	No	Yes	1	9	9
83	R:R:C97	R:R:W87	3.92	No	Yes	0	5	9
84	R:R:C172	R:R:W87	16.98	No	Yes	1	9	9
85	R:R:H89	R:R:S93	4.18	No	No	0	7	5
86	R:R:D91	R:R:Q95	14.36	No	No	0	3	7
87	R:R:D91	R:R:I163	11.2	No	No	0	3	1
88	R:R:C94	R:R:I163	6.55	No	No	0	9	1
89	R:R:C172	R:R:C94	7.28	No	No	1	9	9
90	R:R:L157	R:R:Q95	3.99	No	No	0	4	7
91	R:R:F173	R:R:G98	6.02	Yes	No	0	3	5
92	R:R:I99	R:R:S153	7.74	No	No	0	5	6
93	R:R:L101	R:R:Y102	11.72	No	Yes	1	6	5
94	R:R:F173	R:R:Y102	20.63	Yes	Yes	0	3	5
95	R:R:L272	R:R:Y102	4.69	No	Yes	1	6	5
96	R:R:E103	R:R:T152	7.06	No	No	0	5	4
97	R:R:E103	R:R:F156	7	No	Yes	2	5	4
98	R:R:E103	R:R:R189	5.82	No	Yes	2	5	5
99	R:R:I107	R:R:N104	4.25	No	No	0	7	8
100	R:R:I105	R:R:T275	4.56	No	No	0	7	7
101	R:R:R189	R:R:Y106	9.26	Yes	No	0	5	7
102	R:R:G193	R:R:Y106	4.35	No	No	0	5	7
103	R:R:H245	R:R:Y106	13.07	Yes	No	0	8	7
104	R:R:F111	R:R:I107	7.54	Yes	No	0	7	7
105	R:R:E149	R:R:I107	5.47	Yes	No	0	7	7
106	R:R:F237	R:R:V109	3.93	No	No	0	9	7
107	R:R:F241	R:R:V109	3.93	Yes	No	0	9	7
108	R:R:C113	R:R:G110	3.92	No	No	0	7	5
109	R:R:F111	R:R:I145	10.05	Yes	No	0	7	6
110	R:R:F111	R:R:W146	7.02	Yes	Yes	3	7	9
111	R:R:L112	R:R:Y286	5.86	No	Yes	0	8	9
112	R:R:C113	R:R:L201	4.76	No	No	0	7	8
113	R:R:I115	R:R:R119	3.76	No	No	0	8	9
114	R:R:L201	R:R:S116	4.5	No	No	0	8	9
115	R:R:S116	R:R:S204	6.52	No	No	0	9	6
116	R:R:S116	R:R:Y205	3.82	No	Yes	0	9	8
117	R:R:R119	R:R:Y205	6.17	No	Yes	4	9	8
118	R:R:R119	R:R:Y286	6.17	No	Yes	4	9	9
119	R:R:A124	R:R:Y120	5.34	No	Yes	8	7	8
120	R:R:H125	R:R:Y120	7.62	Yes	Yes	8	6	8
121	R:R:F129	R:R:L121	14.61	No	No	0	6	5
122	R:R:A122	R:R:R133	5.53	No	No	0	8	7
123	R:R:A124	R:R:H125	5.85	No	Yes	8	7	6
124	R:R:H125	R:R:R128	10.16	Yes	No	0	6	4
125	R:R:F129	R:R:H125	7.92	No	Yes	0	6	6
126	R:R:F127	R:R:R128	4.28	No	No	0	5	4
127	R:R:F129	R:R:F132	4.29	No	No	0	6	3
128	R:R:F132	R:R:Q131	12.88	No	No	0	3	4
129	R:R:S142	R:R:W146	3.71	No	Yes	3	6	9
130	R:R:E149	R:R:W146	4.36	Yes	Yes	0	7	9
131	R:R:K148	R:R:T152	10.51	No	No	0	4	4
132	R:R:E149	R:R:L150	3.98	Yes	No	0	7	4
133	R:R:I185	R:R:Y155	7.25	No	No	0	5	8
134	R:R:F156	R:R:F173	7.5	Yes	Yes	0	4	3
135	R:R:F156	R:R:Q182	5.86	Yes	Yes	2	4	4
136	R:R:F156	R:R:I185	6.28	Yes	No	2	4	5
137	R:R:F156	R:R:R189	5.34	Yes	Yes	2	4	5
138	R:R:H159	R:R:W181	30.68	No	No	0	4	3
139	R:R:F173	R:R:V162	3.93	Yes	No	0	3	5
140	R:R:I163	R:R:R170	8.77	No	No	0	1	4
141	R:R:D165	R:R:R170	13.1	No	No	0	2	4
142	R:R:E166	R:R:N167	3.94	No	No	0	3	4
143	R:R:V171	R:R:Y176	3.79	No	Yes	0	3	6
144	R:R:E174	R:R:Y176	15.71	No	Yes	0	5	6
145	R:R:E174	R:R:Y268	12.35	No	Yes	0	5	5
146	R:R:H175	R:R:Q179	13.6	No	No	0	4	1
147	R:R:A261	R:R:Y176	4	No	Yes	1	3	6
148	R:R:F265	R:R:Y176	8.25	Yes	Yes	1	3	6
149	R:R:E255	R:R:P177	4.72	Yes	No	0	3	4
150	R:R:I178	R:R:Q182	5.49	No	Yes	0	4	4
151	R:R:I178	R:R:R183	7.52	No	No	0	4	2
152	R:R:I178	R:R:R251	10.02	No	No	0	4	5
153	R:R:Q179	R:R:W181	8.76	No	No	0	1	3
154	R:R:Q182	R:R:W181	7.67	Yes	No	0	4	3
155	R:R:I185	R:R:Q182	4.12	No	Yes	2	5	4
156	R:R:N186	R:R:Q182	10.56	Yes	Yes	0	4	4
157	R:R:R183	R:R:Y187	6.17	No	No	0	2	4
158	R:R:N186	R:R:R189	9.64	Yes	Yes	0	4	5
159	R:R:N186	R:R:S252	5.96	Yes	No	0	4	6
160	R:R:S252	R:R:Y187	3.82	No	No	0	6	4
161	R:R:V253	R:R:Y187	3.79	No	No	0	4	4
162	R:R:F190	R:R:F194	7.5	Yes	No	1	6	8
163	R:R:F190	R:R:L195	6.09	Yes	No	0	6	4
164	R:R:F190	R:R:H245	5.66	Yes	Yes	1	6	8
165	R:R:F190	R:R:L249	4.87	Yes	No	0	6	5
166	R:R:G193	R:R:P197	4.06	No	No	0	5	9
167	R:R:F194	R:R:H245	16.97	No	Yes	1	8	8
168	R:R:F196	R:R:P197	4.33	No	No	0	5	9
169	R:R:F196	R:R:L200	9.74	No	No	0	5	6
170	R:R:I198	R:R:L202	5.71	No	No	0	6	3
171	R:R:F237	R:R:I198	5.02	No	No	0	9	6
172	R:R:I198	R:R:L238	5.71	No	No	0	6	5
173	R:R:F237	R:R:L201	7.31	No	No	0	9	8
174	R:R:V230	R:R:Y205	5.05	No	Yes	0	7	8
175	R:R:T233	R:R:Y205	3.75	No	Yes	4	7	8
176	R:R:Y205	R:R:Y286	4.96	Yes	Yes	4	8	9
177	R:R:G207	R:R:Q206	4.93	No	No	0	3	4
178	R:R:G207	R:R:R210	4.5	No	No	0	3	3
179	R:R:L209	R:R:R213	6.07	No	No	0	5	4
180	R:R:L209	R:R:V230	11.92	No	No	0	5	7
181	R:R:R210	R:R:R214	5.33	No	No	0	3	4
182	R:R:I226	R:R:V212	9.22	No	No	0	7	8
183	R:R:S215	R:R:T218	4.8	No	No	0	5	3
184	R:R:Q219	R:R:T218	4.25	No	No	0	4	3
185	R:R:K223	R:R:T218	6.01	No	No	0	7	3
186	R:R:Q219	R:R:R222	9.35	No	No	0	4	5
187	R:R:D224	R:R:K220	8.3	No	No	0	5	4
188	R:R:Q225	R:R:R222	9.35	No	No	0	7	5
189	R:R:E291	R:R:Q225	7.65	No	No	0	6	7
190	R:R:Q227	R:R:R228	4.67	No	No	0	6	6
191	R:R:L229	R:R:V289	5.96	No	No	0	7	6
192	R:R:L285	R:R:T233	8.84	Yes	No	0	8	7
193	R:R:T233	R:R:Y286	4.99	No	Yes	4	7	9
194	R:R:I236	R:R:L285	5.71	No	Yes	0	6	8
195	R:R:C240	R:R:F241	5.59	No	Yes	0	8	9
196	R:R:F241	R:R:H245	7.92	Yes	Yes	0	9	8
197	R:R:F241	R:R:N278	10.87	Yes	No	0	9	9
198	R:R:H245	R:R:Y244	6.53	Yes	Yes	1	8	7
199	R:R:Y244	R:R:Y268	3.97	Yes	Yes	1	7	5
200	R:R:S271	R:R:Y244	6.36	No	Yes	0	7	7
201	R:R:L272	R:R:Y244	7.03	No	Yes	1	6	7
202	R:R:T275	R:R:Y244	6.24	No	Yes	0	7	7
203	R:R:L247	R:R:V264	4.47	Yes	No	0	4	5
204	R:R:L247	R:R:Y268	5.86	Yes	Yes	0	4	5
205	R:R:E255	R:R:R251	15.12	Yes	No	1	3	5
206	R:R:A261	R:R:R251	4.15	No	No	1	3	5
207	R:R:F260	R:R:W254	4.01	No	No	0	1	2
208	R:R:E255	R:R:F260	7	Yes	No	0	3	1
209	R:R:A261	R:R:E255	4.53	No	Yes	1	3	3
210	R:R:D259	R:R:S257	7.36	No	No	0	1	5
211	R:R:F265	R:R:H269	18.1	Yes	No	1	3	4
212	R:R:L272	R:R:Y268	5.86	No	Yes	1	6	5
213	R:R:D282	R:R:N278	10.77	No	No	0	9	9
214	R:R:F288	R:R:V284	9.18	Yes	No	0	7	6
215	R:R:C287	R:R:F288	5.59	No	Yes	0	6	7
216	R:R:H294	R:R:T293	5.48	No	No	0	8	8
217	R:R:I115	R:R:Y59	3.63	No	Yes	0	8	7
218	R:R:I208	R:R:Y205	3.63	No	Yes	0	8	8
219	R:R:F69	R:R:N104	3.62	No	No	0	7	8
220	R:R:K51	R:R:Y47	3.58	No	No	0	6	2
221	R:R:P283	R:R:S42	3.56	No	No	0	9	8
222	R:R:L74	R:R:Y28	3.52	No	Yes	0	7	8
223	R:R:C97	R:R:S73	3.44	No	No	0	5	6
224	R:R:H130	R:R:R133	3.39	No	No	0	5	7
225	R:R:G57	R:R:Q49	3.29	No	No	0	7	4
226	R:R:L82	R:R:P25	3.28	No	No	0	4	6
227	R:R:L242	R:R:P243	3.28	No	No	0	4	9
228	R:R:C13	R:R:I15	3.27	No	Yes	0	7	2
229	R:R:C61	R:R:I50	3.27	No	No	0	6	5
230	R:R:S290	R:R:T292	3.2	No	No	0	8	6
231	R:R:I50	R:R:V58	3.07	No	No	0	5	6
232	R:R:K223	R:R:V212	3.04	No	No	0	7	8
233	R:R:L285	R:R:S232	3	Yes	No	0	8	6
234	R:R:L100	R:R:V96	2.98	No	No	0	5	4
235	R:R:L121	R:R:V117	2.98	No	No	0	5	5
236	R:R:L191	R:R:V192	2.98	No	No	0	4	4
237	R:R:L242	R:R:V246	2.98	No	No	0	4	5
238	R:R:L247	R:R:V250	2.98	Yes	No	0	4	5
239	R:R:G207	R:R:Y120	2.9	No	Yes	0	3	8
240	R:R:E149	R:R:S153	2.87	Yes	No	0	7	6
241	R:R:K220	R:R:K223	2.87	No	No	0	4	7
242	R:R:A38	R:R:F288	2.77	No	Yes	0	7	7
243	R:R:L78	R:R:L82	2.77	No	No	0	7	4
244	R:R:A180	R:R:R183	2.77	No	No	0	1	2
245	R:R:L248	R:R:N186	2.75	No	Yes	0	5	4
246	R:R:L92	R:R:Q95	2.66	No	No	0	2	7
247	R:R:L231	R:R:Q227	2.66	No	No	0	4	6
248	R:R:F69	R:R:V65	2.62	No	No	0	7	5
249	R:R:D118	R:R:E55	2.6	No	No	0	8	6
250	R:R:F277	R:R:T30	2.59	No	No	0	4	4
251	R:R:H169	R:R:N167	2.55	No	No	0	2	4
252	R:R:S204	R:R:Y120	2.54	No	Yes	0	6	8
253	R:R:F265	R:R:I19	2.51	Yes	No	0	3	3
254	R:R:H84	R:R:Q21	2.47	No	No	0	3	4
255	R:R:H89	R:R:Q79	2.47	No	No	0	7	4
256	R:R:E291	R:R:H294	2.46	No	No	0	6	8
257	R:R:F36	R:R:L68	2.44	No	No	0	6	7
258	R:R:F194	R:R:L242	2.44	No	No	0	8	4
259	R:R:N86	R:R:R170	2.41	No	No	0	4	4
260	R:R:D118	R:R:R133	2.38	No	No	0	8	7
261	R:R:C61	R:R:G46	1.96	No	No	0	6	6
262	R:R:A211	R:R:V123	1.7	No	No	0	5	8
263	R:R:A137	R:R:T134	1.68	No	No	0	1	6
264	R:R:L32	R:R:P75	1.64	No	No	6	6	9
265	R:R:L74	R:R:P75	1.64	No	No	6	7	9
266	R:R:L274	R:R:P243	1.64	No	No	0	7	9
267	R:R:A281	R:R:I236	1.62	No	No	0	6	6
268	R:R:V29	R:R:V33	1.6	No	No	0	6	5
269	R:R:V33	R:R:V34	1.6	No	No	0	5	6
270	R:R:V139	R:R:V143	1.6	No	No	0	3	4
271	R:R:V230	R:R:V234	1.6	No	No	0	7	7
272	R:R:T30	R:R:V26	1.59	No	No	0	4	5
273	R:R:G90	R:R:H89	1.59	No	No	0	8	7
274	R:R:A267	R:R:L247	1.58	No	Yes	0	5	4
275	R:R:T18	R:R:T22	1.57	No	No	0	3	3
276	R:R:H125	R:R:P126	1.53	Yes	No	0	6	8
277	R:R:K136	R:R:T134	1.5	No	No	0	4	6
278	R:R:Q49	R:R:T292	1.42	No	No	0	4	6
279	R:R:E55	R:R:T134	1.41	No	No	0	6	6
280	R:R:C199	R:R:F196	1.4	No	No	0	3	5
281	R:R:L191	R:R:L195	1.38	No	No	0	4	4
282	R:R:L229	R:R:L285	1.38	No	Yes	0	7	8
283	R:R:L209	R:R:Q227	1.33	No	No	0	5	6
284	R:R:F260	R:R:S257	1.32	No	No	0	1	5
285	R:R:E160	R:R:E161	1.27	No	No	0	5	4
286	R:R:E161	R:R:Q179	1.27	No	No	0	4	1

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:I15	5.9175	4	1	2
2	R:R:H20	12.8825	4	1	4
3	R:R:Y28	4.606	5	0	8
4	R:R:N39	5.39	4	0	9
5	R:R:Y59	5.546	5	0	7
6	R:R:D67	5.64	5	0	9
7	R:R:W77	7.045	4	1	6
8	R:R:D85	14.6125	4	1	4
9	R:R:W87	9.37	5	1	9
10	R:R:Y102	10.9475	4	1	5
11	R:R:F111	7.586	5	3	7
12	R:R:Y120	4.6	4	8	8
13	R:R:H125	6.616	5	8	6
14	R:R:W146	5.185	4	3	9
15	R:R:E149	4.17	4	0	7
16	R:R:F156	6.396	5	2	4
17	R:R:F173	9.52	4	0	3
18	R:R:Y176	7.8	5	1	6
19	R:R:Q182	6.74	5	2	4
20	R:R:N186	7.2275	4	0	4
21	R:R:R189	7.515	4	2	5
22	R:R:F190	6.03	4	1	6
23	R:R:Y205	4.56333	6	4	8
24	R:R:F241	7.0775	4	0	9
25	R:R:Y244	6.026	5	1	7
26	R:R:H245	10.03	5	1	8
27	R:R:L247	3.7225	4	0	4
28	R:R:E255	7.8425	4	1	3
29	R:R:F265	8.888	5	1	3
30	R:R:Y268	7.01	4	1	5
31	R:R:L285	4.7325	4	0	8
32	R:R:Y286	5.495	4	4	9
33	R:R:F288	5.2975	4	0	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:F265	R:R:H20	33.5289	6.79	Yes	Yes	1	3	4
2	R:R:D85	R:R:H20	46.3831	15.13	Yes	Yes	1	4	4
3	R:R:D85	R:R:Y80	53.021	11.49	Yes	No	1	4	5
4	R:R:W87	R:R:Y80	11.6439	10.61	Yes	No	1	9	5
5	R:R:C94	R:R:W87	47.8958	7.84	No	Yes	1	9	9
6	R:R:C94	R:R:I163	45.7046	6.55	No	No	0	9	1
7	R:R:I163	R:R:R170	33.6023	8.77	No	No	0	1	4
8	R:R:N86	R:R:R170	28.633	2.41	No	No	0	4	4
9	R:R:H169	R:R:N86	10.6629	14.03	No	No	0	2	4
10	R:R:F265	R:R:I19	13.6976	2.51	Yes	No	0	3	3
11	R:R:H20	R:R:V81	49.3353	6.92	Yes	No	0	4	5
12	R:R:V81	R:R:Y28	47.2816	3.79	No	Yes	0	5	8
13	R:R:L273	R:R:Y28	30.265	5.86	No	Yes	0	5	8
14	R:R:L273	R:R:V27	23.5537	11.92	No	No	0	5	5
15	R:R:F277	R:R:V27	21.2799	7.87	No	No	0	4	5
16	R:R:F277	R:R:V31	14.3486	3.93	No	No	0	4	7
17	R:R:V280	R:R:V31	12.0015	4.81	No	No	0	7	7
18	R:R:E174	R:R:Y176	45.8421	15.71	No	Yes	0	5	6
19	R:R:E174	R:R:Y268	47.5199	12.35	No	Yes	0	5	5
20	R:R:Y244	R:R:Y268	43.2383	3.97	Yes	Yes	1	7	5
21	R:R:H245	R:R:Y244	63.9773	6.53	Yes	Yes	1	8	7
22	R:R:F241	R:R:H245	97.3412	7.92	Yes	Yes	0	9	8
23	R:R:F241	R:R:N278	32.9238	10.87	Yes	No	0	9	9
24	R:R:D282	R:R:N278	32.5021	10.77	No	No	0	9	9
25	R:R:D282	R:R:D67	33.1255	7.98	No	Yes	0	9	9
26	R:R:D67	R:R:N39	77.5374	4.04	Yes	Yes	0	9	9
27	R:R:L68	R:R:N39	10.7729	8.24	No	Yes	0	7	9
28	R:R:L272	R:R:Y268	14.1744	5.86	No	Yes	1	6	5
29	R:R:L272	R:R:Y102	32.5021	4.69	No	Yes	1	6	5
30	R:R:L101	R:R:Y102	33.5381	11.72	No	Yes	1	6	5
31	R:R:L101	R:R:Y70	99.2849	4.69	No	No	0	6	6
32	R:R:C279	R:R:Y70	98.8998	5.38	No	No	0	8	6
33	R:R:C279	R:R:D67	99.1748	6.22	No	Yes	0	8	9
34	R:R:W77	R:R:Y80	43.1649	4.82	Yes	No	1	6	5
35	R:R:L101	R:R:W77	66.0768	9.11	No	Yes	1	6	6
36	R:R:A38	R:R:P283	57.486	3.74	No	No	0	7	9
37	R:R:N39	R:R:P283	62.0702	4.89	Yes	No	0	9	9
38	R:R:A38	R:R:F288	55.1389	2.77	No	Yes	0	7	7
39	R:R:C287	R:R:F288	48.2076	5.59	No	Yes	0	6	7
40	R:R:C287	R:R:F45	45.8146	6.98	No	No	0	6	6
41	R:R:F45	R:R:Y44	10.7729	13.41	No	No	0	6	4
42	R:R:F45	R:R:T293	33.5564	12.97	No	No	0	6	8
43	R:R:F241	R:R:V109	72.5497	3.93	Yes	No	0	9	7
44	R:R:F237	R:R:V109	71.2478	3.93	No	No	0	9	7
45	R:R:F237	R:R:L201	66.5628	7.31	No	No	0	9	8
46	R:R:L201	R:R:S116	64.6466	4.5	No	No	0	8	9
47	R:R:S116	R:R:Y205	61.2176	3.82	No	Yes	0	9	8
48	R:R:R119	R:R:Y205	30.9984	6.17	No	Yes	4	9	8
49	R:R:I115	R:R:R119	65.6276	3.76	No	No	0	8	9
50	R:R:I115	R:R:L60	18.7494	5.71	No	No	0	8	7
51	R:R:L56	R:R:L60	16.1914	5.54	No	No	0	7	7
52	R:R:L56	R:R:N54	13.4959	5.49	No	No	0	7	7
53	R:R:N54	R:R:Q49	10.7821	3.96	No	No	0	7	4
54	R:R:I115	R:R:Y59	46.869	3.63	No	Yes	0	8	7
55	R:R:D118	R:R:Y59	26.7626	6.9	No	Yes	0	8	7
56	R:R:D118	R:R:E55	16.4206	2.6	No	No	0	8	6
57	R:R:A138	R:R:Y59	13.7435	4	No	Yes	0	7	7
58	R:R:A138	R:R:V58	11.0296	5.09	No	No	0	7	6
59	R:R:D67	R:R:L63	100	4.07	Yes	No	0	9	9
60	R:R:F111	R:R:L63	48.5743	3.65	Yes	No	0	7	9
61	R:R:F111	R:R:W146	15.403	7.02	Yes	Yes	3	7	9
62	R:R:L112	R:R:L63	74.1909	5.54	No	No	0	8	9
63	R:R:I107	R:R:N104	10.7362	4.25	No	No	0	7	8
64	R:R:F111	R:R:I107	23.4437	7.54	Yes	No	0	7	7
65	R:R:C97	R:R:W87	13.0375	3.92	No	Yes	0	5	9
66	R:R:N86	R:R:Q83	15.8889	5.28	No	No	0	4	4
67	R:R:Q79	R:R:Q83	10.6262	8.96	No	No	7	4	4
68	R:R:D91	R:R:I163	10.6629	11.2	No	No	0	3	1
69	R:R:F173	R:R:Y102	36.9854	20.63	Yes	Yes	0	3	5
70	R:R:E149	R:R:I107	10.6079	5.47	Yes	No	0	7	7
71	R:R:E149	R:R:S153	10.5162	2.87	Yes	No	0	7	6
72	R:R:E149	R:R:W146	10.5345	4.36	Yes	Yes	0	7	9
73	R:R:A261	R:R:Y176	26.8543	4	No	Yes	1	3	6
74	R:R:I178	R:R:R251	16.2006	10.02	No	No	0	4	5
75	R:R:I178	R:R:Q182	23.3061	5.49	No	Yes	0	4	4
76	R:R:F156	R:R:Q182	30.8701	5.86	Yes	Yes	2	4	4
77	R:R:H245	R:R:Y106	47.1899	13.07	Yes	No	0	8	7
78	R:R:R189	R:R:Y106	39.5709	9.26	Yes	No	0	5	7
79	R:R:F156	R:R:R189	17.9609	5.34	Yes	Yes	2	4	5
80	R:R:N186	R:R:Q182	13.4868	10.56	Yes	Yes	0	4	4
81	R:R:N186	R:R:R189	20.8582	9.64	Yes	Yes	0	4	5
82	R:R:G193	R:R:Y106	14.4769	4.35	No	No	0	5	7
83	R:R:Y205	R:R:Y286	27.5328	4.96	Yes	Yes	4	8	9
84	R:R:L112	R:R:Y286	72.7056	5.86	No	Yes	0	8	9
85	R:R:S116	R:R:S204	43.5592	6.52	No	No	0	9	6
86	R:R:S204	R:R:Y120	40.9737	2.54	No	Yes	0	6	8
87	R:R:H125	R:R:Y120	24.9931	7.62	Yes	Yes	8	6	8
88	R:R:F129	R:R:H125	14.1102	7.92	No	Yes	0	6	6
89	R:R:Q182	R:R:W181	21.1882	7.67	Yes	No	0	4	3
90	R:R:Q179	R:R:W181	14.1927	8.76	No	No	0	1	3
91	R:R:A261	R:R:E255	15.5588	4.53	No	Yes	1	3	3
92	R:R:F190	R:R:H245	12.414	5.66	Yes	Yes	1	6	8
93	R:R:F194	R:R:H245	12.414	16.97	No	Yes	1	8	8
94	R:R:G193	R:R:P197	11.6164	4.06	No	No	0	5	9
95	R:R:V230	R:R:Y205	17.2183	5.05	No	Yes	0	7	8
96	R:R:G207	R:R:Y120	11.323	2.9	No	Yes	0	3	8
97	R:R:L209	R:R:V230	12.5332	11.92	No	No	0	5	7
98	R:R:H294	R:R:T293	31.0535	5.48	No	No	0	8	8
99	R:R:E291	R:R:H294	28.5321	2.46	No	No	0	6	8
100	R:R:E291	R:R:Q225	25.9833	7.65	No	No	0	6	7
101	R:R:Q225	R:R:R222	23.627	9.35	No	No	0	7	5
102	R:R:Q219	R:R:R222	21.0507	9.35	No	No	0	4	5
103	R:R:Q219	R:R:T218	18.456	4.25	No	No	0	4	3
104	R:R:K223	R:R:T218	13.2117	6.01	No	No	0	7	3
105	R:R:L285	R:R:T233	17.4475	8.84	Yes	No	0	8	7
106	R:R:L247	R:R:Y268	11.9098	5.86	Yes	Yes	0	4	5
107	R:R:E255	R:R:F260	14.2202	7	Yes	No	0	3	1
108	R:R:F194	R:R:L242	10.1494	2.44	No	No	0	8	4
109	R:R:F265	R:R:Y176	29.5223	8.25	Yes	Yes	1	3	6
110	R:R:W77	R:R:W87	52.0125	7.5	Yes	Yes	1	6	9
111	R:R:R119	R:R:Y286	36.7929	6.17	No	Yes	4	9	9
112	R:R:W77	R:R:Y102	30.3842	6.75	Yes	Yes	1	6	5
113	R:R:F156	R:R:F173	33.153	7.5	Yes	Yes	0	4	3
114	R:R:L272	R:R:Y244	18.0893	7.03	No	Yes	1	6	7
115	R:R:T233	R:R:Y286	10.7729	4.99	No	Yes	4	7	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 9BHM_nogp

PDB Summary
PDB	9BHM_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.65
Number of Linked Nodes	262
Number of Links	286
Number of Hubs	33
Number of Links mediated by Hubs	123
Number of Communities	8
Number of Nodes involved in Communities	49
Number of Links involved in Communities	60

Path Summary
Number Of Nodes in MetaPath	116
Number Of Links MetaPath	115
Number of Shortest Paths	39692
Length Of Smallest Path	3
Average Path Length	13.385
Length of Longest Path	34
Minimum Path Strength	1.27
Average Path Strength	6.52603
Maximum Path Strength	20.17
Minimum Path Correlation	0.7
Average Path Correlation	0.923605
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	4.16667
Average % Of Corr. Nodes	49.4074
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	37.5899
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier
SCOP2	Family Identifier
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q15743
Sequence	>9BHM_nogp_Chain_R C T I D H T I H Q T L A P V V Y V T V L V V G F P A N C L S L Y F G Y L Q I K A R N E L G V Y L C N L T V A D L F Y I C S L P F W L Q Y V L Q H D N W S H G D L S C Q V C G I L L Y E N I Y I S V G F L C C I S V D R Y L A V A H P F R F H Q F R T L K A A V G V S V V I W A K E L L T S I Y F L M H E E V I E D E N Q H R V C F E H Y P I Q A W Q R A I N Y Y R F L V G F L F P I C L L L A S Y Q G I L R A V R R S H G T Q K S R K D Q I Q R L V L S T V V I F L A C F L P Y H V L L L V R S V W E A S C D F A K G V F N A Y H F S L L L T S F N C V A D P V L Y C F V S E T T H Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	9BHM	A	Orphan	Orphan	GPR68	Homo sapiens	-	-	Gs/β1	2.9	2025-01-22	doi.org/10.1016/j.cell.2024.11.036
	9BHM (No Gprot)	A	Orphan	Orphan	GPR68	Homo sapiens	-	-		2.9	2025-01-22	doi.org/10.1016/j.cell.2024.11.036
	9BI6	A	Orphan	Orphan	GPR68	Homo sapiens	-	-	chim(Gs-CtGq)/β1/γ2	2.9	2025-01-22	doi.org/10.1016/j.cell.2024.11.036
	9BI6 (No Gprot)	A	Orphan	Orphan	GPR68	Homo sapiens	-	-		2.9	2025-01-22	doi.org/10.1016/j.cell.2024.11.036
	8Z3O	A	Orphan	Orphan	GPR68	Homo sapiens	-	-	-	3.3	2025-04-23	To be published
	8Z5H	A	Orphan	Orphan	GPR68	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	3.3	2025-04-23	To be published
	8Z5H (No Gprot)	A	Orphan	Orphan	GPR68	Homo sapiens	-	-		3.3	2025-04-23	To be published
	8Z68	A	Orphan	Orphan	GPR68	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	2.64	2025-04-23	To be published
	8Z68 (No Gprot)	A	Orphan	Orphan	GPR68	Homo sapiens	-	-		2.64	2025-04-23	To be published

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 9BHM_nogp.zip

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