psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:E46	M:M:L1	6.63	No	No	0	0	0
2	L:L:S63	M:M:L1	10.51	No	No	0	0	0
3	M:M:C23	M:M:L4	4.76	No	Yes	3	0	0
4	M:M:I28	M:M:L4	5.71	Yes	Yes	3	0	0
5	M:M:C88	M:M:L4	3.17	Yes	Yes	3	0	0
6	M:M:L4	M:M:S90	6.01	Yes	No	3	0	0
7	M:M:S24	M:M:T5	4.8	No	No	0	0	0
8	M:M:P7	M:M:Q6	4.74	Yes	Yes	3	0	0
9	M:M:C88	M:M:Q6	3.05	Yes	Yes	3	0	0
10	M:M:G101	M:M:Q6	3.29	No	Yes	0	0	0
11	M:M:G103	M:M:Q6	6.58	No	Yes	0	0	0
12	M:M:Q6	M:M:T104	11.34	Yes	Yes	3	0	0
13	M:M:P7	M:M:V11	3.53	Yes	Yes	3	0	0
14	M:M:I21	M:M:P7	3.39	No	Yes	3	0	0
15	M:M:P7	M:M:S22	3.56	Yes	No	0	0	0
16	M:M:P7	M:M:T104	5.25	Yes	Yes	3	0	0
17	M:M:V11	M:M:V19	3.21	Yes	Yes	3	0	0
18	M:M:I21	M:M:V11	4.61	No	Yes	3	0	0
19	M:M:T104	M:M:V11	4.76	Yes	Yes	3	0	0
20	M:M:L106	M:M:V11	4.47	No	Yes	3	0	0
21	M:M:S12	M:M:T107	3.2	No	No	0	0	0
22	M:M:L109	M:M:S12	4.5	No	No	0	0	0
23	M:M:A14	M:M:Q17	4.55	No	No	0	0	0
24	M:M:P15	M:M:R16	4.32	No	No	0	0	0
25	M:M:A74	M:M:R18	4.15	No	No	0	0	0
26	M:M:R18	M:M:R76	4.26	No	No	0	0	0
27	M:M:I75	M:M:V19	3.07	Yes	Yes	3	0	0
28	M:M:L78	M:M:V19	5.96	No	Yes	0	0	0
29	M:M:L106	M:M:V19	2.98	No	Yes	3	0	0
30	M:M:S72	M:M:T20	4.8	No	No	0	0	0
31	M:M:I21	M:M:T104	9.12	No	Yes	3	0	0
32	M:M:C23	M:M:W35	3.92	No	Yes	3	0	0
33	M:M:C23	M:M:C88	7.28	No	Yes	3	0	0
34	M:M:G25	M:M:I28	5.29	No	Yes	0	0	0
35	M:M:N26	M:M:S27	2.98	No	No	0	0	0
36	M:M:I28	M:M:V33	6.14	Yes	No	3	0	0
37	M:M:A71	M:M:I28	3.25	No	Yes	3	0	0
38	M:M:I28	M:M:S90	3.1	Yes	No	3	0	0
39	M:M:N30	M:M:N31	4.09	No	Yes	1	0	0
40	M:M:D93	M:M:N30	6.73	No	No	1	0	0
41	M:M:N30	R:R:N110	4.09	No	No	0	0	6
42	M:M:N31	M:M:W91	4.52	Yes	Yes	1	0	0
43	M:M:D93	M:M:N31	12.12	No	Yes	1	0	0
44	L:L:S104	M:M:N31	4.47	No	Yes	1	0	0
45	M:M:N31	R:R:R109	9.64	Yes	Yes	1	0	5
46	M:M:A32	M:M:Y50	4	No	Yes	0	0	0
47	M:M:A32	M:M:D51	4.63	No	No	0	0	0
48	M:M:V33	M:M:W35	4.9	No	Yes	3	0	0
49	M:M:A71	M:M:V33	5.09	No	No	3	0	0
50	L:L:T106	M:M:N34	4.39	No	No	0	0	0
51	L:L:W107	M:M:N34	3.39	Yes	No	0	0	0
52	M:M:I48	M:M:W35	7.05	No	Yes	0	0	0
53	M:M:L73	M:M:W35	13.67	No	Yes	0	0	0
54	M:M:C88	M:M:W35	7.84	Yes	Yes	3	0	0
55	M:M:L46	M:M:Y36	8.21	Yes	Yes	1	0	0
56	M:M:T89	M:M:Y36	3.75	Yes	Yes	1	0	0
57	L:L:S108	M:M:Y36	5.09	Yes	Yes	1	0	0
58	L:L:W111	M:M:Y36	7.72	Yes	Yes	1	0	0
59	M:M:L39	M:M:Q37	6.65	No	Yes	3	0	0
60	M:M:K45	M:M:Q37	6.78	No	Yes	0	0	0
61	M:M:L47	M:M:Q37	7.99	No	Yes	0	0	0
62	M:M:A84	M:M:Q37	3.03	Yes	Yes	3	0	0
63	M:M:Q37	M:M:Y86	15.78	Yes	Yes	3	0	0
64	M:M:P44	M:M:Q38	9.47	No	Yes	1	0	0
65	M:M:Q38	M:M:Y87	6.76	Yes	Yes	1	0	0
66	L:L:Q39	M:M:Q38	11.52	Yes	Yes	1	0	0
67	L:L:Y95	M:M:Q38	4.51	Yes	Yes	1	0	0
68	M:M:K42	M:M:L39	4.23	No	No	0	0	0
69	M:M:A84	M:M:L39	4.73	Yes	No	3	0	0
70	L:L:Y95	M:M:A43	5.34	Yes	No	0	0	0
71	L:L:Y95	M:M:P44	12.52	Yes	No	1	0	0
72	L:L:W111	M:M:P44	16.21	Yes	No	1	0	0
73	M:M:L46	M:M:Y49	5.86	Yes	Yes	1	0	0
74	M:M:L46	M:M:P55	8.21	Yes	No	1	0	0
75	L:L:W107	M:M:L46	5.69	Yes	Yes	1	0	0
76	M:M:L47	M:M:V58	2.98	No	No	0	0	0
77	M:M:F62	M:M:L47	6.09	Yes	No	0	0	0
78	M:M:Y49	M:M:Y50	3.97	Yes	Yes	1	0	0
79	M:M:Q53	M:M:Y49	11.27	Yes	Yes	1	0	0
80	M:M:P55	M:M:Y49	8.34	No	Yes	1	0	0
81	L:L:W107	M:M:Y49	31.83	Yes	Yes	1	0	0
82	M:M:Y49	R:R:Y185	8.94	Yes	Yes	1	0	7
83	L:L:W107	M:M:Y50	6.75	Yes	Yes	1	0	0
84	M:M:Y50	R:R:F134	3.09	Yes	Yes	1	0	5
85	M:M:Y50	R:R:E157	5.61	Yes	Yes	1	0	8
86	M:M:D51	M:M:R66	19.06	No	No	0	0	0
87	M:M:D51	R:R:K209	4.15	No	Yes	0	0	7
88	M:M:D52	M:M:S63	4.42	No	No	0	0	0
89	M:M:D52	M:M:G64	5.03	No	No	0	0	0
90	M:M:Q53	R:R:N208	5.28	Yes	Yes	1	0	5
91	M:M:Q53	R:R:K209	10.85	Yes	Yes	1	0	7
92	M:M:Q53	R:R:Q235	5.12	Yes	No	1	0	4
93	M:M:L54	R:R:R255	12.15	No	Yes	0	0	4
94	M:M:P55	M:M:V58	7.07	No	No	0	0	0
95	M:M:S56	R:R:E251	4.31	No	Yes	1	0	5
96	M:M:S56	R:R:I253	3.1	No	Yes	1	0	4
97	M:M:S56	R:R:R274	3.95	No	Yes	1	0	3
98	M:M:R61	M:M:S59	10.54	Yes	No	0	0	0
99	M:M:F62	M:M:R61	3.21	Yes	Yes	3	0	0
100	M:M:G77	M:M:R61	3	No	Yes	0	0	0
101	M:M:Q79	M:M:R61	8.18	No	Yes	3	0	0
102	M:M:E81	M:M:R61	9.3	No	Yes	3	0	0
103	M:M:D82	M:M:R61	10.72	Yes	Yes	3	0	0
104	M:M:F62	M:M:I75	8.79	Yes	Yes	3	0	0
105	M:M:D82	M:M:F62	8.36	Yes	Yes	3	0	0
106	M:M:F62	M:M:Y86	4.13	Yes	Yes	3	0	0
107	M:M:I75	M:M:L73	7.14	Yes	No	0	0	0
108	M:M:D82	M:M:I75	4.2	Yes	Yes	3	0	0
109	M:M:L78	M:M:V108	5.96	No	No	0	0	0
110	M:M:E81	M:M:Q79	11.47	No	No	3	0	0
111	M:M:D82	M:M:E81	6.5	Yes	No	3	0	0
112	M:M:D82	M:M:Y86	3.45	Yes	Yes	3	0	0
113	M:M:E83	M:M:T107	5.64	No	No	0	0	0
114	M:M:A84	M:M:Y86	4	Yes	Yes	3	0	0
115	M:M:D85	M:M:Y87	5.75	No	Yes	0	0	0
116	M:M:D85	M:M:R105	14.29	No	No	0	0	0
117	M:M:G103	M:M:Y87	4.35	No	Yes	0	0	0
118	L:L:Q39	M:M:Y87	4.51	Yes	Yes	1	0	0
119	L:L:G44	M:M:Y87	5.79	No	Yes	0	0	0
120	L:L:L45	M:M:Y87	10.55	Yes	Yes	1	0	0
121	M:M:Q98	M:M:T89	8.5	Yes	Yes	1	0	0
122	M:M:F100	M:M:T89	18.16	Yes	Yes	1	0	0
123	L:L:T106	M:M:T89	4.71	No	Yes	1	0	0
124	M:M:D96	M:M:W91	4.47	No	Yes	1	0	0
125	L:L:W47	M:M:W91	3.75	Yes	Yes	1	0	0
126	L:L:R50	M:M:W91	14.99	Yes	Yes	1	0	0
127	L:L:Y103	M:M:W91	6.75	Yes	Yes	1	0	0
128	L:L:S104	M:M:W91	4.94	No	Yes	1	0	0
129	M:M:D92	M:M:S94	7.36	No	No	3	0	0
130	M:M:D92	M:M:L95	5.43	No	Yes	3	0	0
131	M:M:D92	M:M:L99	5.43	No	Yes	3	0	0
132	M:M:D93	R:R:I85	7	No	No	0	0	6
133	M:M:L95	M:M:S94	4.5	Yes	No	3	0	0
134	M:M:L95	M:M:L99	4.15	Yes	Yes	3	0	0
135	L:L:Y103	M:M:D96	11.49	Yes	No	1	0	0
136	L:L:W47	M:M:S97	7.41	Yes	No	0	0	0
137	L:L:P62	M:M:S97	5.34	No	No	0	0	0
138	M:M:F100	M:M:Q98	10.54	Yes	Yes	1	0	0
139	L:L:N35	M:M:Q98	6.6	Yes	Yes	1	0	0
140	L:L:W47	M:M:Q98	17.52	Yes	Yes	1	0	0
141	L:L:T106	M:M:Q98	11.34	No	Yes	1	0	0
142	L:L:V37	M:M:F100	5.24	Yes	Yes	1	0	0
143	L:L:L45	M:M:F100	12.18	Yes	Yes	1	0	0
144	M:M:Q111	M:M:Y143	9.02	No	Yes	0	0	0
145	M:M:N173	M:M:Q111	5.28	No	No	0	0	0
146	M:M:K113	M:M:Y143	4.78	No	Yes	0	0	0
147	M:M:I139	M:M:P116	3.39	No	Yes	5	0	0
148	M:M:F142	M:M:P116	7.22	Yes	Yes	5	0	0
149	M:M:P116	M:M:V198	3.53	Yes	Yes	5	0	0
150	M:M:H200	M:M:P116	7.63	Yes	Yes	5	0	0
151	M:M:V118	M:M:V198	3.21	No	Yes	0	0	0
152	M:M:K207	M:M:V118	4.55	No	No	0	0	0
153	M:M:F121	M:M:T119	3.89	Yes	No	0	0	0
154	M:M:C137	M:M:L120	3.17	No	No	5	0	0
155	M:M:C196	M:M:L120	6.35	No	No	5	0	0
156	M:M:L120	M:M:V209	10.43	No	No	0	0	0
157	M:M:F121	M:M:V136	3.93	Yes	Yes	6	0	0
158	M:M:F121	M:M:L138	3.65	Yes	Yes	6	0	0
159	L:L:L132	M:M:F121	10.96	Yes	Yes	6	0	0
160	M:M:P122	M:M:V209	10.6	No	No	0	0	0
161	M:M:L128	M:M:P123	6.57	No	Yes	5	0	0
162	M:M:A133	M:M:P123	3.74	No	Yes	0	0	0
163	M:M:L135	M:M:P123	6.57	Yes	Yes	5	0	0
164	M:M:P123	M:M:W188	22.97	Yes	Yes	5	0	0
165	M:M:E127	M:M:S124	4.31	Yes	No	6	0	0
166	L:L:F130	M:M:S124	5.28	Yes	No	6	0	0
167	L:L:P131	M:M:S124	3.56	Yes	No	0	0	0
168	M:M:E126	M:M:Q129	3.82	No	No	0	0	0
169	L:L:P131	M:M:E126	12.58	Yes	No	0	0	0
170	M:M:E127	M:M:K132	12.15	Yes	No	0	0	0
171	M:M:E127	M:M:T134	9.88	Yes	Yes	0	0	0
172	L:L:F130	M:M:E127	11.66	Yes	Yes	6	0	0
173	L:L:L149	M:M:E127	3.98	Yes	Yes	6	0	0
174	M:M:L128	M:M:W188	6.83	No	Yes	5	0	0
175	L:L:D152	M:M:K132	5.53	Yes	No	0	0	0
176	M:M:T134	M:M:Y180	3.75	Yes	Yes	0	0	0
177	M:M:S182	M:M:T134	3.2	No	Yes	0	0	0
178	L:L:K151	M:M:T134	12.01	Yes	Yes	0	0	0
179	M:M:L135	M:M:W151	10.25	Yes	Yes	5	0	0
180	M:M:L135	M:M:L181	5.54	Yes	Yes	5	0	0
181	M:M:L135	M:M:L183	4.15	Yes	Yes	5	0	0
182	M:M:L135	M:M:W188	3.42	Yes	Yes	5	0	0
183	M:M:L135	M:M:Y194	8.21	Yes	Yes	5	0	0
184	M:M:L138	M:M:V136	4.47	Yes	Yes	6	0	0
185	M:M:V136	M:M:Y180	7.57	Yes	Yes	6	0	0
186	L:L:L132	M:M:V136	10.43	Yes	Yes	6	0	0
187	L:L:L149	M:M:V136	5.96	Yes	Yes	6	0	0
188	L:L:S187	M:M:V136	3.23	Yes	Yes	6	0	0
189	M:M:C137	M:M:C196	7.28	No	No	5	0	0
190	L:L:F174	M:M:L138	15.83	Yes	Yes	0	0	0
191	L:L:S187	M:M:L138	3	Yes	Yes	6	0	0
192	L:L:V189	M:M:L138	2.98	No	Yes	0	0	0
193	M:M:A177	M:M:I139	3.25	No	No	0	0	0
194	M:M:I139	M:M:V198	7.68	No	Yes	5	0	0
195	M:M:D141	M:M:S140	7.36	No	No	16	0	0
196	M:M:Q170	M:M:S140	4.33	Yes	No	16	0	0
197	M:M:D141	M:M:Q170	6.53	No	Yes	16	0	0
198	M:M:D141	M:M:N172	5.39	No	No	16	0	0
199	M:M:F142	M:M:G145	3.01	Yes	No	5	0	0
200	M:M:F142	M:M:V147	14.42	Yes	No	5	0	0
201	M:M:F142	M:M:Y175	11.35	Yes	Yes	5	0	0
202	M:M:F142	M:M:H200	5.66	Yes	Yes	5	0	0
203	M:M:P144	M:M:Y143	9.74	No	Yes	0	0	0
204	M:M:Y143	M:M:Y175	3.97	Yes	Yes	0	0	0
205	M:M:H200	M:M:P144	3.05	Yes	No	5	0	0
206	M:M:E201	M:M:P144	11	No	No	5	0	0
207	M:M:G145	M:M:P167	4.06	No	No	0	0	0
208	M:M:G145	M:M:Y175	4.35	No	Yes	5	0	0
209	M:M:A146	M:M:E201	3.02	No	No	0	0	0
210	M:M:H200	M:M:V147	4.15	Yes	No	5	0	0
211	M:M:T148	M:M:T199	4.71	No	No	0	0	0
212	M:M:T164	M:M:V149	11.11	No	No	5	0	0
213	M:M:S179	M:M:V149	9.7	No	No	5	0	0
214	M:M:V149	M:M:V198	3.21	No	Yes	5	0	0
215	M:M:V162	M:M:W151	7.36	No	Yes	0	0	0
216	M:M:S179	M:M:W151	3.71	No	Yes	5	0	0
217	M:M:L181	M:M:W151	18.22	Yes	Yes	5	0	0
218	M:M:C196	M:M:W151	11.75	No	Yes	5	0	0
219	M:M:K152	M:M:P157	6.69	No	No	0	0	0
220	M:M:K152	M:M:Q197	12.2	No	No	0	0	0
221	M:M:A153	M:M:H191	7.32	No	Yes	5	0	0
222	M:M:A153	M:M:Y194	6.67	No	Yes	5	0	0
223	M:M:D154	M:M:H191	5.04	No	Yes	0	0	0
224	M:M:H191	M:M:S156	5.58	Yes	No	0	0	0
225	M:M:L181	M:M:V158	2.98	Yes	No	0	0	0
226	L:L:Q179	M:M:E163	10.19	Yes	No	0	0	0
227	M:M:S179	M:M:T164	9.59	No	No	5	0	0
228	M:M:S178	M:M:T165	6.4	No	No	0	0	0
229	L:L:V177	M:M:T165	3.17	No	No	0	0	0
230	M:M:P167	M:M:T166	5.25	No	No	0	0	0
231	L:L:P175	M:M:S168	7.13	No	No	0	0	0
232	M:M:K169	M:M:Y175	10.75	No	Yes	0	0	0
233	M:M:N172	M:M:Q170	9.24	No	Yes	16	0	0
234	M:M:K174	M:M:Q170	4.07	No	Yes	16	0	0
235	M:M:A176	M:M:Q170	4.55	No	Yes	0	0	0
236	M:M:K174	M:M:N172	15.39	No	No	16	0	0
237	M:M:S178	M:M:Y180	6.36	No	Yes	0	0	0
238	L:L:F174	M:M:S178	5.28	Yes	No	0	0	0
239	L:L:L149	M:M:Y180	3.52	Yes	Yes	6	0	0
240	L:L:V177	M:M:Y180	5.05	No	Yes	0	0	0
241	L:L:S187	M:M:Y180	8.9	Yes	Yes	6	0	0
242	M:M:L181	M:M:L183	11.07	Yes	Yes	5	0	0
243	M:M:L183	M:M:Q187	9.32	Yes	No	0	0	0
244	M:M:L183	M:M:Y194	8.21	Yes	Yes	5	0	0
245	M:M:P185	M:M:T184	3.5	No	No	18	0	0
246	M:M:E186	M:M:T184	4.23	No	No	18	0	0
247	M:M:Q187	M:M:T184	15.59	No	No	0	0	0
248	M:M:E186	M:M:P185	6.29	No	No	18	0	0
249	M:M:K189	M:M:W188	3.48	No	Yes	5	0	0
250	M:M:W188	M:M:Y194	6.75	Yes	Yes	5	0	0
251	M:M:P211	M:M:W188	13.51	No	Yes	5	0	0
252	M:M:K189	M:M:P211	6.69	No	No	5	0	0
253	M:M:H191	M:M:Y194	11.98	Yes	Yes	5	0	0
254	M:M:K192	M:M:S193	9.18	No	No	0	0	0
255	M:M:S193	M:M:T208	3.2	No	No	0	0	0
256	M:M:S195	M:M:T208	6.4	No	No	0	0	0
257	M:M:E206	M:M:Q197	12.74	No	No	0	0	0
258	M:M:T199	M:M:T204	7.85	No	No	0	0	0
259	M:M:E201	M:M:H200	9.85	No	Yes	5	0	0
260	M:M:H200	M:M:S203	4.18	Yes	No	0	0	0
261	L:L:V2	L:L:Y27	8.83	No	Yes	1	0	0
262	L:L:R98	L:L:V2	6.54	Yes	No	1	0	0
263	L:L:N110	L:L:V2	11.82	No	No	1	0	0
264	L:L:Q3	L:L:V5	4.3	No	No	0	0	0
265	L:L:C22	L:L:L4	4.76	No	No	8	0	0
266	L:L:G24	L:L:L4	3.42	No	No	0	0	0
267	L:L:C96	L:L:L4	4.76	Yes	No	8	0	0
268	L:L:C22	L:L:Q6	3.05	No	Yes	8	0	0
269	L:L:C96	L:L:Q6	9.16	Yes	Yes	8	0	0
270	L:L:G112	L:L:Q6	4.93	No	Yes	0	0	0
271	L:L:Q113	L:L:Q6	5.12	No	Yes	0	0	0
272	L:L:G114	L:L:Q6	4.93	No	Yes	0	0	0
273	L:L:Q6	L:L:T115	8.5	Yes	No	0	0	0
274	L:L:I20	L:L:S7	3.1	Yes	No	0	0	0
275	L:L:S21	L:L:S7	3.26	No	No	0	0	0
276	L:L:A9	L:L:L116	4.73	No	No	0	0	0
277	L:L:E10	L:L:L18	10.6	No	Yes	0	0	0
278	L:L:T118	L:L:V11	4.76	No	No	0	0	0
279	L:L:P155	L:L:V11	8.84	Yes	No	0	0	0
280	L:L:E16	L:L:K12	6.75	No	No	0	0	0
281	L:L:K12	L:L:L18	7.05	No	Yes	0	0	0
282	L:L:E16	L:L:K13	6.75	No	No	0	0	0
283	L:L:P14	L:L:V119	5.3	No	No	0	0	0
284	L:L:L18	L:L:W83	5.69	Yes	Yes	8	0	0
285	L:L:L18	L:L:L86	5.54	Yes	No	8	0	0
286	L:L:L18	L:L:V117	2.98	Yes	No	0	0	0
287	L:L:K19	L:L:S71	3.06	No	No	10	0	0
288	L:L:K19	L:L:Y80	15.53	No	Yes	10	0	0
289	L:L:K19	L:L:Q82	16.27	No	No	0	0	0
290	L:L:I20	L:L:W36	5.87	Yes	Yes	8	0	0
291	L:L:I20	L:L:L81	5.71	Yes	Yes	8	0	0
292	L:L:I20	L:L:T115	6.08	Yes	No	0	0	0
293	L:L:S21	L:L:Y80	3.82	No	Yes	0	0	0
294	L:L:C22	L:L:C96	7.28	No	Yes	8	0	0
295	L:L:I76	L:L:R23	3.76	Yes	No	10	0	0
296	L:L:R23	L:L:T78	6.47	No	No	10	0	0
297	L:L:F29	L:L:G24	3.01	Yes	No	0	0	0
298	L:L:G26	L:L:S25	3.71	No	No	0	0	0
299	L:L:F29	L:L:Y27	4.13	Yes	Yes	0	0	0
300	L:L:Y27	L:L:Y32	6.95	Yes	Yes	1	0	0
301	L:L:R98	L:L:Y27	17.49	Yes	Yes	1	0	0
302	L:L:R28	L:L:T30	9.06	Yes	No	0	0	0
303	L:L:R28	L:L:S31	9.22	Yes	No	1	0	0
304	L:L:R28	R:R:K129	9.9	Yes	Yes	1	0	5
305	L:L:R28	R:R:D151	5.96	Yes	No	1	0	4
306	L:L:R28	R:R:F153	7.48	Yes	Yes	0	0	5
307	L:L:F29	L:L:I34	5.02	Yes	No	0	0	0
308	L:L:F29	L:L:P53	10.11	Yes	No	0	0	0
309	L:L:F29	L:L:N77	20.54	Yes	No	0	0	0
310	L:L:T30	L:L:T54	6.28	No	Yes	0	0	0
311	L:L:K74	L:L:T30	4.5	No	No	0	0	0
312	L:L:S31	R:R:K129	4.59	No	Yes	1	0	5
313	L:L:R98	L:L:Y32	17.49	Yes	Yes	1	0	0
314	L:L:E100	L:L:Y32	5.61	Yes	Yes	1	0	0
315	L:L:Y32	R:R:I155	3.63	Yes	Yes	1	0	5
316	L:L:R50	L:L:W33	24.99	Yes	No	0	0	0
317	L:L:W33	L:L:Y57	3.86	No	Yes	0	0	0
318	L:L:L99	L:L:W33	4.56	Yes	No	0	0	0
319	L:L:A79	L:L:I34	4.87	No	No	0	0	0
320	L:L:N35	L:L:V37	4.43	Yes	Yes	1	0	0
321	L:L:N35	L:L:W47	9.04	Yes	Yes	1	0	0
322	L:L:L99	L:L:N35	10.98	Yes	Yes	0	0	0
323	L:L:M48	L:L:W36	3.49	Yes	Yes	8	0	0
324	L:L:V70	L:L:W36	3.68	No	Yes	0	0	0
325	L:L:L81	L:L:W36	18.22	Yes	Yes	8	0	0
326	L:L:C96	L:L:W36	7.84	Yes	Yes	8	0	0
327	L:L:L45	L:L:V37	5.96	Yes	Yes	1	0	0
328	L:L:V37	L:L:W111	3.68	Yes	Yes	1	0	0
329	L:L:L40	L:L:R38	15.79	No	Yes	0	0	0
330	L:L:E46	L:L:R38	6.98	No	Yes	0	0	0
331	L:L:F64	L:L:R38	11.76	No	Yes	0	0	0
332	L:L:R38	L:L:Y94	10.29	Yes	Yes	0	0	0
333	L:L:L45	L:L:Q39	7.99	Yes	Yes	1	0	0
334	L:L:Q39	L:L:Y95	6.76	Yes	Yes	1	0	0
335	L:L:L40	L:L:P41	3.28	No	No	0	0	0
336	L:L:K43	L:L:L40	12.69	No	No	0	0	0
337	L:L:G92	L:L:P41	4.06	No	No	0	0	0
338	L:L:G49	L:L:W47	8.44	No	Yes	0	0	0
339	L:L:R50	L:L:W47	4	Yes	Yes	1	0	0
340	L:L:S61	L:L:W47	4.94	No	Yes	0	0	0
341	L:L:F64	L:L:M48	6.22	No	Yes	0	0	0
342	L:L:M48	L:L:V68	4.56	Yes	No	8	0	0
343	L:L:L81	L:L:M48	7.07	Yes	Yes	8	0	0
344	L:L:M48	L:L:Y94	5.99	Yes	Yes	0	0	0
345	L:L:N59	L:L:R50	13.26	No	Yes	1	0	0
346	L:L:R50	L:L:Y103	7.2	Yes	Yes	1	0	0
347	L:L:I51	L:L:T58	4.56	Yes	No	0	0	0
348	L:L:I51	L:L:V70	4.61	Yes	No	0	0	0
349	L:L:A72	L:L:I51	4.87	No	Yes	0	0	0
350	L:L:D52	L:L:P53	4.83	Yes	No	0	0	0
351	L:L:D52	L:L:T54	8.67	Yes	Yes	1	0	0
352	L:L:D52	L:L:D55	3.99	Yes	Yes	1	0	0
353	L:L:D52	R:R:R80	9.53	Yes	Yes	1	0	4
354	L:L:D52	R:R:H105	6.3	Yes	Yes	1	0	7
355	L:L:D55	L:L:T54	5.78	Yes	Yes	1	0	0
356	L:L:T54	R:R:K129	9.01	Yes	Yes	1	0	5
357	L:L:D55	L:L:Y57	3.45	Yes	Yes	1	0	0
358	L:L:D55	R:R:R80	13.1	Yes	Yes	1	0	4
359	L:L:N59	L:L:Y57	11.63	No	Yes	1	0	0
360	L:L:Y103	L:L:Y57	4.96	Yes	Yes	1	0	0
361	L:L:Y57	R:R:D36	5.75	Yes	No	1	0	3
362	L:L:Y57	R:R:R38	21.61	Yes	No	1	0	4
363	L:L:Y57	R:R:T56	7.49	Yes	No	1	0	5
364	L:L:Y57	R:R:K58	3.58	Yes	Yes	1	0	5
365	L:L:Y57	R:R:R80	13.38	Yes	Yes	1	0	4
366	L:L:T58	L:L:Y60	8.74	No	Yes	19	0	0
367	L:L:T58	R:R:E35	8.47	No	No	19	0	1
368	L:L:N59	L:L:Y103	8.14	No	Yes	1	0	0
369	L:L:K65	L:L:Y60	5.97	No	Yes	0	0	0
370	L:L:V70	L:L:Y60	8.83	No	Yes	0	0	0
371	L:L:Y60	R:R:E35	3.37	Yes	No	19	0	1
372	L:L:P62	L:L:S61	5.34	No	No	0	0	0
373	L:L:F64	L:L:S61	3.96	No	No	0	0	0
374	L:L:K65	R:R:E34	12.15	No	No	0	0	4
375	L:L:L81	L:L:V68	7.45	Yes	No	8	0	0
376	L:L:V68	L:L:W83	9.81	No	Yes	8	0	0
377	L:L:S71	L:L:Y80	3.82	No	Yes	10	0	0
378	L:L:D73	L:L:S75	7.36	No	No	10	0	0
379	L:L:D73	L:L:I76	5.6	No	Yes	10	0	0
380	L:L:I76	L:L:S75	6.19	Yes	No	10	0	0
381	L:L:I76	L:L:T78	9.12	Yes	No	10	0	0
382	L:L:T78	L:L:Y80	11.24	No	Yes	10	0	0
383	L:L:L81	L:L:W83	5.69	Yes	Yes	8	0	0
384	L:L:L86	L:L:W83	10.25	No	Yes	8	0	0
385	L:L:D90	L:L:W83	6.7	No	Yes	0	0	0
386	L:L:W83	L:L:Y94	16.4	Yes	Yes	0	0	0
387	L:L:L86	L:L:V119	7.45	No	No	0	0	0
388	L:L:K87	L:L:S89	3.06	No	No	0	0	0
389	L:L:D90	L:L:K87	5.53	No	No	0	0	0
390	L:L:T91	L:L:V119	6.35	No	No	0	0	0
391	L:L:M93	L:L:Y95	7.18	No	Yes	0	0	0
392	L:L:L116	L:L:M93	4.24	No	No	0	0	0
393	L:L:V117	L:L:Y94	6.31	No	Yes	0	0	0
394	L:L:W111	L:L:Y95	6.75	Yes	Yes	1	0	0
395	L:L:A97	L:L:S108	3.42	No	Yes	1	0	0
396	L:L:A97	L:L:W111	10.37	No	Yes	1	0	0
397	L:L:E100	L:L:R98	4.65	Yes	Yes	1	0	0
398	L:L:N110	L:L:R98	6.03	No	Yes	1	0	0
399	L:L:L99	L:L:S105	3	Yes	No	0	0	0
400	L:L:L99	L:L:S108	6.01	Yes	Yes	0	0	0
401	L:L:E100	L:L:P101	3.14	Yes	No	1	0	0
402	L:L:E100	L:L:W107	15.27	Yes	Yes	1	0	0
403	L:L:E100	L:L:V109	4.28	Yes	No	1	0	0
404	L:L:E100	R:R:K183	4.05	Yes	Yes	1	0	6
405	L:L:P101	R:R:F130	8.67	No	Yes	1	0	6
406	L:L:P101	R:R:I155	5.08	No	Yes	1	0	5
407	L:L:G102	R:R:E107	4.91	No	Yes	1	0	6
408	L:L:G102	R:R:F130	3.01	No	Yes	1	0	6
409	L:L:Y103	R:R:K58	9.55	Yes	Yes	1	0	5
410	L:L:Y103	R:R:Y82	14.89	Yes	Yes	1	0	4
411	L:L:Y103	R:R:E107	3.37	Yes	Yes	1	0	6
412	L:L:S104	R:R:R109	13.18	No	Yes	1	0	5
413	L:L:V109	L:L:W107	3.68	No	Yes	1	0	0
414	L:L:W107	R:R:Y185	5.79	Yes	Yes	1	0	7
415	L:L:S108	L:L:W111	6.18	Yes	Yes	1	0	0
416	L:L:S120	L:L:S121	3.26	No	No	0	0	0
417	L:L:A122	L:L:F154	8.32	No	No	0	0	0
418	L:L:P155	L:L:T124	5.25	Yes	No	0	0	0
419	L:L:D152	L:L:K125	4.15	Yes	No	6	0	0
420	L:L:K125	L:L:L183	7.05	No	No	6	0	0
421	L:L:G126	L:L:P127	4.06	No	Yes	9	0	0
422	L:L:G126	L:L:S211	3.71	No	No	9	0	0
423	L:L:G126	L:L:T213	5.46	No	No	9	0	0
424	L:L:P127	L:L:Y153	5.56	Yes	Yes	9	0	0
425	L:L:H208	L:L:P127	7.63	Yes	Yes	9	0	0
426	L:L:P127	L:L:T213	5.25	Yes	No	9	0	0
427	L:L:C148	L:L:V129	3.42	No	Yes	0	0	0
428	L:L:V129	L:L:V206	6.41	Yes	No	0	0	0
429	L:L:V129	L:L:V215	3.21	Yes	No	0	0	0
430	L:L:K217	L:L:V129	4.55	No	Yes	0	0	0
431	L:L:F130	L:L:K151	3.72	Yes	Yes	6	0	0
432	L:L:K217	L:L:P131	8.36	No	Yes	0	0	0
433	L:L:P131	L:L:V219	5.3	Yes	No	0	0	0
434	L:L:G147	L:L:L132	3.42	No	Yes	0	0	0
435	L:L:L132	L:L:L149	4.15	Yes	Yes	6	0	0
436	L:L:L132	L:L:S187	3	Yes	Yes	6	0	0
437	L:L:L146	L:L:P134	6.57	Yes	Yes	0	0	0
438	L:L:L197	L:L:P134	3.28	Yes	Yes	0	0	0
439	L:L:T143	L:L:T191	3.14	No	No	0	0	0
440	L:L:L146	L:L:W162	4.56	Yes	Yes	11	0	0
441	L:L:L146	L:L:V190	2.98	Yes	Yes	11	0	0
442	L:L:L146	L:L:Y202	7.03	Yes	Yes	11	0	0
443	L:L:L146	L:L:V219	7.45	Yes	No	0	0	0
444	L:L:G147	L:L:V189	3.68	No	No	0	0	0
445	L:L:C148	L:L:C204	7.28	No	No	0	0	0
446	L:L:K151	L:L:L149	8.46	Yes	Yes	6	0	0
447	L:L:L149	L:L:S187	6.01	Yes	Yes	6	0	0
448	L:L:V150	L:L:Y153	6.31	No	Yes	9	0	0
449	L:L:L186	L:L:V150	4.47	No	No	9	0	0
450	L:L:V150	L:L:V206	4.81	No	No	0	0	0
451	L:L:D152	L:L:K151	6.91	Yes	Yes	6	0	0
452	L:L:K151	L:L:Q179	6.78	Yes	Yes	6	0	0
453	L:L:K151	L:L:S185	9.18	Yes	No	6	0	0
454	L:L:D152	L:L:L183	6.79	Yes	No	6	0	0
455	L:L:E156	L:L:Y153	12.35	Yes	Yes	9	0	0
456	L:L:V158	L:L:Y153	12.62	No	Yes	0	0	0
457	L:L:Y153	L:L:Y184	6.95	Yes	Yes	9	0	0
458	L:L:L186	L:L:Y153	8.21	No	Yes	9	0	0
459	L:L:F154	L:L:P155	15.89	No	Yes	0	0	0
460	L:L:F154	L:L:Y184	6.19	No	Yes	0	0	0
461	L:L:H208	L:L:P155	3.05	Yes	Yes	9	0	0
462	L:L:P155	L:L:P210	7.79	Yes	No	9	0	0
463	L:L:E156	L:L:P157	4.72	Yes	No	0	0	0
464	L:L:A176	L:L:E156	3.02	No	Yes	0	0	0
465	L:L:E156	L:L:Y184	15.71	Yes	Yes	9	0	0
466	L:L:H208	L:L:V158	5.54	Yes	No	0	0	0
467	L:L:S188	L:L:V160	8.08	No	No	0	0	0
468	L:L:V160	L:L:V206	3.21	No	No	0	0	0
469	L:L:L167	L:L:W162	3.42	No	Yes	11	0	0
470	L:L:V171	L:L:W162	7.36	No	Yes	11	0	0
471	L:L:V190	L:L:W162	12.26	Yes	Yes	11	0	0
472	L:L:C204	L:L:W162	7.84	No	Yes	0	0	0
473	L:L:L167	L:L:N163	5.49	No	No	0	0	0
474	L:L:N205	L:L:S164	5.96	No	No	0	0	0
475	L:L:L167	L:L:V190	5.96	No	Yes	11	0	0
476	L:L:V171	L:L:V190	3.21	No	Yes	11	0	0
477	L:L:S188	L:L:T173	9.59	No	No	0	0	0
478	L:L:A176	L:L:L186	4.73	No	No	0	0	0
479	L:L:L178	L:L:Y184	17.58	No	Yes	0	0	0
480	L:L:Q179	L:L:S181	4.33	Yes	No	0	0	0
481	L:L:Q179	L:L:S185	11.55	Yes	No	6	0	0
482	L:L:L183	L:L:S181	4.5	No	No	0	0	0
483	L:L:L197	L:L:V192	2.98	Yes	No	0	0	0
484	L:L:V192	L:L:Y202	13.88	No	Yes	0	0	0
485	L:L:P193	L:L:S196	3.56	No	Yes	0	0	0
486	L:L:S196	L:L:T199	3.2	Yes	No	0	0	0
487	L:L:Q200	L:L:S196	4.33	No	Yes	11	0	0
488	L:L:S196	L:L:Y202	3.82	Yes	Yes	11	0	0
489	L:L:L197	L:L:P221	3.28	Yes	No	0	0	0
490	L:L:Q200	L:L:Y202	5.64	No	Yes	11	0	0
491	L:L:I203	L:L:T201	3.04	No	No	0	0	0
492	L:L:K218	L:L:T201	4.5	No	No	0	0	0
493	L:L:D216	L:L:N205	9.42	No	No	0	0	0
494	L:L:K214	L:L:N207	4.2	No	No	0	0	0
495	L:L:H208	L:L:P210	18.3	Yes	No	9	0	0
496	L:L:H208	L:L:S211	8.37	Yes	No	9	0	0
497	L:L:S211	L:L:T213	6.4	No	No	9	0	0
498	L:L:E220	L:L:K218	9.45	No	No	0	0	0
499	L:L:E220	L:L:P221	3.14	No	No	0	0	0
500	R:R:D43	R:R:P28	3.22	No	No	0	4	2
501	R:R:C29	R:R:C41	5.46	No	No	0	9	9
502	R:R:C29	R:R:P48	5.65	No	Yes	0	9	9
503	R:R:E30	R:R:H32	3.69	No	No	0	3	5
504	R:R:F37	R:R:Q33	19.91	No	No	0	1	5
505	R:R:D36	R:R:R38	15.48	No	No	1	3	4
506	R:R:D36	R:R:Q55	3.92	No	No	0	3	4
507	R:R:F37	R:R:Q55	5.86	No	No	0	1	4
508	R:R:L50	R:R:V39	2.98	Yes	Yes	2	5	6
509	R:R:P51	R:R:V39	3.53	Yes	Yes	2	5	6
510	R:R:T54	R:R:V39	7.93	No	Yes	2	7	6
511	R:R:L57	R:R:V39	2.98	Yes	Yes	2	7	6
512	R:R:K42	R:R:T40	3	No	Yes	0	2	8
513	R:R:K58	R:R:T40	7.51	Yes	Yes	0	5	8
514	R:R:I60	R:R:T40	3.04	No	Yes	0	4	8
515	R:R:C41	R:R:I44	6.55	No	No	0	9	5
516	R:R:C41	R:R:L59	3.17	No	No	0	9	6
517	R:R:I44	R:R:P48	6.77	No	Yes	0	5	9
518	R:R:I44	R:R:T62	4.56	No	No	0	5	7
519	R:R:Q45	R:R:R46	8.18	No	No	0	4	1
520	R:R:I47	R:R:P48	3.39	No	Yes	0	4	9
521	R:R:I47	R:R:L64	7.14	No	No	0	4	6
522	R:R:L50	R:R:P51	4.93	Yes	Yes	2	5	5
523	R:R:L50	R:R:L57	6.92	Yes	Yes	2	5	7
524	R:R:L50	R:R:L75	4.15	Yes	No	0	5	6
525	R:R:P51	R:R:T54	5.25	Yes	No	2	5	7
526	R:R:N77	R:R:S53	2.98	No	No	0	8	5
527	R:R:R80	R:R:T56	9.06	Yes	No	1	4	5
528	R:R:L57	R:R:L59	4.15	Yes	No	0	7	6
529	R:R:F72	R:R:L57	3.65	Yes	Yes	2	9	7
530	R:R:I78	R:R:L57	4.28	No	Yes	0	7	7
531	R:R:K58	R:R:Y82	5.97	Yes	Yes	1	5	4
532	R:R:L59	R:R:V83	4.47	No	No	0	6	6
533	R:R:I60	R:R:S84	6.19	No	No	0	4	7
534	R:R:L64	R:R:T62	7.37	No	No	2	6	7
535	R:R:D86	R:R:T62	10.12	Yes	No	2	8	7
536	R:R:H63	R:R:T88	4.11	No	No	0	4	4
537	R:R:D86	R:R:L64	4.07	Yes	No	2	8	6
538	R:R:R65	R:R:T66	5.17	No	No	0	4	5
539	R:R:Q91	R:R:T66	7.09	No	No	0	3	5
540	R:R:E93	R:R:T66	9.88	No	No	0	6	5
541	R:R:I67	R:R:P68	3.39	Yes	No	0	5	5
542	R:R:I67	R:R:L89	5.71	Yes	No	2	5	8
543	R:R:I67	R:R:L92	4.28	Yes	Yes	2	5	8
544	R:R:F97	R:R:I67	3.77	Yes	Yes	2	9	5
545	R:R:A71	R:R:P68	3.74	No	No	0	8	5
546	R:R:E93	R:R:P68	4.72	No	No	0	6	5
547	R:R:H70	R:R:S69	5.58	No	No	0	4	4
548	R:R:E93	R:R:S69	5.75	No	No	0	6	4
549	R:R:H70	R:R:H95	5.97	No	No	0	4	5
550	R:R:A71	R:R:F72	5.55	No	Yes	0	8	9
551	R:R:F72	R:R:I81	6.28	Yes	Yes	2	9	8
552	R:R:F72	R:R:F97	8.57	Yes	Yes	2	9	9
553	R:R:F72	R:R:L100	3.65	Yes	No	0	9	8
554	R:R:N74	R:R:S73	5.96	No	No	0	4	4
555	R:R:I78	R:R:L75	7.14	No	No	0	7	6
556	R:R:I78	R:R:I81	5.89	No	Yes	0	7	8
557	R:R:S79	R:R:T104	4.8	No	No	0	7	5
558	R:R:R80	R:R:Y82	15.43	Yes	Yes	1	4	4
559	R:R:H105	R:R:R80	15.8	Yes	Yes	1	7	4
560	R:R:F97	R:R:I81	3.77	Yes	Yes	2	9	8
561	R:R:I81	R:R:V103	3.07	Yes	No	0	8	5
562	R:R:H105	R:R:Y82	5.44	Yes	Yes	1	7	4
563	R:R:E107	R:R:Y82	7.86	Yes	Yes	1	6	4
564	R:R:I108	R:R:V83	4.61	No	No	0	8	6
565	R:R:I85	R:R:S84	7.74	No	No	0	6	7
566	R:R:D86	R:R:L89	6.79	Yes	No	2	8	8
567	R:R:L89	R:R:L92	4.15	No	Yes	2	8	8
568	R:R:N113	R:R:Q90	10.56	No	No	0	4	4
569	R:R:Q91	R:R:Y116	4.51	No	Yes	0	3	3
570	R:R:L92	R:R:S96	3	Yes	No	0	8	7
571	R:R:L114	R:R:L92	5.54	No	Yes	2	8	8
572	R:R:I117	R:R:L92	4.28	No	Yes	2	8	8
573	R:R:H95	R:R:S94	4.18	No	No	0	5	4
574	R:R:D120	R:R:S94	4.42	No	No	0	5	4
575	R:R:H95	R:R:Y98	16.33	No	No	0	5	2
576	R:R:F97	R:R:S96	7.93	Yes	No	0	9	7
577	R:R:F97	R:R:I106	6.28	Yes	No	0	9	7
578	R:R:N99	R:R:Y98	12.79	No	No	0	5	2
579	R:R:K123	R:R:Y98	7.17	No	No	0	4	2
580	R:R:L100	R:R:V103	5.96	No	No	0	8	5
581	R:R:K102	R:R:S101	3.06	No	No	0	4	4
582	R:R:I106	R:R:V103	3.07	No	No	0	7	5
583	R:R:H105	R:R:T104	8.21	Yes	No	0	7	5
584	R:R:H105	R:R:K129	5.24	Yes	Yes	1	7	5
585	R:R:F130	R:R:H105	5.66	Yes	Yes	1	6	7
586	R:R:I106	R:R:L128	4.28	No	Yes	0	7	9
587	R:R:E107	R:R:R109	8.14	Yes	Yes	1	6	5
588	R:R:E107	R:R:F130	5.83	Yes	Yes	1	6	6
589	R:R:E107	R:R:F134	8.16	Yes	Yes	1	6	5
590	R:R:I108	R:R:T111	4.56	No	No	0	8	5
591	R:R:N110	R:R:R109	10.85	No	Yes	0	6	5
592	R:R:F134	R:R:R109	11.76	Yes	Yes	1	5	5
593	R:R:N110	R:R:N135	8.17	No	No	0	6	8
594	R:R:L114	R:R:T111	7.37	No	No	2	8	5
595	R:R:T111	R:R:T136	4.71	No	Yes	2	5	9
596	R:R:N135	R:R:R112	18.08	No	No	0	8	6
597	R:R:L114	R:R:T136	4.42	No	Yes	2	8	9
598	R:R:D118	R:R:Y116	10.34	No	Yes	20	5	3
599	R:R:P119	R:R:Y116	4.17	No	Yes	20	4	3
600	R:R:I117	R:R:L138	7.14	No	Yes	2	8	8
601	R:R:I117	R:R:P142	3.39	No	Yes	2	8	9
602	R:R:D118	R:R:P119	6.44	No	No	20	5	4
603	R:R:D118	R:R:D120	5.32	No	No	0	5	5
604	R:R:D143	R:R:P119	4.83	No	No	0	5	4
605	R:R:D120	R:R:K146	5.53	No	Yes	0	5	4
606	R:R:K123	R:R:K146	7.18	No	Yes	0	4	4
607	R:R:L125	R:R:L128	8.3	Yes	Yes	2	8	9
608	R:R:L125	R:R:V147	2.98	Yes	No	2	8	7
609	R:R:L128	R:R:V147	2.98	Yes	No	2	9	7
610	R:R:L128	R:R:S149	3	Yes	No	2	9	8
611	R:R:F154	R:R:L128	6.09	Yes	Yes	2	6	9
612	R:R:D151	R:R:K129	13.83	No	Yes	1	4	5
613	R:R:F130	R:R:G132	3.01	Yes	No	0	6	5
614	R:R:F130	R:R:I155	3.77	Yes	Yes	1	6	5
615	R:R:E157	R:R:F130	4.66	Yes	Yes	1	8	6
616	R:R:L131	R:R:L156	4.15	No	Yes	0	8	7
617	R:R:F134	R:R:G132	4.52	Yes	No	0	5	5
618	R:R:I133	R:R:T136	6.08	No	Yes	0	8	9
619	R:R:I133	R:R:P142	3.39	No	Yes	0	8	9
620	R:R:E157	R:R:F134	16.32	Yes	Yes	1	8	5
621	R:R:F134	R:R:T159	6.49	Yes	Yes	1	5	5
622	R:R:G137	R:R:T136	3.64	No	Yes	0	8	9
623	R:R:L138	R:R:T136	7.37	Yes	Yes	2	8	9
624	R:R:N161	R:R:T136	5.85	Yes	Yes	2	8	9
625	R:R:L138	R:R:P142	4.93	Yes	Yes	2	8	9
626	R:R:L138	R:R:M164	4.24	Yes	Yes	2	8	7
627	R:R:F141	R:R:P142	10.11	Yes	Yes	2	7	9
628	R:R:F141	R:R:L144	3.65	Yes	Yes	2	7	7
629	R:R:F141	R:R:I158	3.77	Yes	Yes	2	7	7
630	R:R:F141	R:R:M164	4.98	Yes	Yes	2	7	7
631	R:R:F141	R:R:P168	5.78	Yes	Yes	0	7	6
632	R:R:F141	R:R:F172	9.65	Yes	Yes	0	7	8
633	R:R:F141	R:R:F189	4.29	Yes	Yes	2	7	8
634	R:R:L144	R:R:P142	4.93	Yes	Yes	2	7	9
635	R:R:I158	R:R:P142	3.39	Yes	Yes	2	7	9
636	R:R:M164	R:R:P142	3.35	Yes	Yes	2	7	9
637	R:R:D143	R:R:T145	8.67	No	No	0	5	4
638	R:R:L144	R:R:L156	4.15	Yes	Yes	2	7	7
639	R:R:L144	R:R:L175	8.3	Yes	Yes	2	7	7
640	R:R:K146	R:R:T145	4.5	Yes	No	0	4	4
641	R:R:L175	R:R:V147	4.47	Yes	No	2	7	7
642	R:R:F154	R:R:S149	5.28	Yes	No	2	6	8
643	R:R:F153	R:R:I155	5.02	Yes	Yes	0	5	5
644	R:R:F153	R:R:T179	3.89	Yes	No	0	5	5
645	R:R:F153	R:R:T181	7.78	Yes	No	0	5	7
646	R:R:F154	R:R:L156	3.65	Yes	Yes	2	6	7
647	R:R:F154	R:R:L175	8.53	Yes	Yes	2	6	7
648	R:R:C176	R:R:F154	4.19	No	Yes	0	6	6
649	R:R:F154	R:R:L180	4.87	Yes	No	0	6	7
650	R:R:I158	R:R:L156	7.14	Yes	Yes	2	7	7
651	R:R:L156	R:R:L175	4.15	Yes	Yes	2	7	7
652	R:R:E157	R:R:T159	8.47	Yes	Yes	1	8	5
653	R:R:E157	R:R:K183	13.5	Yes	Yes	1	8	6
654	R:R:I158	R:R:N161	4.25	Yes	Yes	2	7	8
655	R:R:I158	R:R:L184	4.28	Yes	Yes	2	7	8
656	R:R:I158	R:R:N187	7.08	Yes	Yes	2	7	9
657	R:R:D160	R:R:T159	7.23	No	Yes	0	8	5
658	R:R:T159	R:R:Y185	6.24	Yes	Yes	1	5	7
659	R:R:D160	R:R:N186	8.08	No	No	0	8	7
660	R:R:M164	R:R:N161	7.01	Yes	Yes	2	7	8
661	R:R:N161	R:R:N187	6.81	Yes	Yes	2	8	9
662	R:R:P162	R:R:Y163	13.91	No	No	0	7	4
663	R:R:F189	R:R:M164	8.71	Yes	Yes	2	8	7
664	R:R:S166	R:R:T165	4.8	No	No	0	5	4
665	R:R:I167	R:R:P168	3.39	Yes	Yes	0	7	6
666	R:R:F189	R:R:I167	10.05	Yes	Yes	0	8	7
667	R:R:I167	R:R:V192	3.07	Yes	No	0	7	7
668	R:R:A196	R:R:I167	3.25	No	Yes	0	9	7
669	R:R:A171	R:R:P168	3.74	No	Yes	0	7	6
670	R:R:N170	R:R:V169	7.39	No	No	0	8	5
671	R:R:N170	R:R:N198	9.54	No	Yes	0	8	7
672	R:R:A171	R:R:F172	4.16	No	Yes	0	7	8
673	R:R:F172	R:R:L182	8.53	Yes	No	0	8	6
674	R:R:F172	R:R:F197	4.29	Yes	Yes	0	8	9
675	R:R:N198	R:R:Q173	9.24	Yes	No	21	7	2
676	R:R:G199	R:R:Q173	3.29	No	No	21	7	2
677	R:R:L180	R:R:L182	6.92	No	No	0	7	6
678	R:R:L182	R:R:V205	4.47	No	Yes	0	6	7
679	R:R:K183	R:R:Y185	4.78	Yes	Yes	1	6	7
680	R:R:K183	R:R:Y206	3.58	Yes	Yes	1	6	6
681	R:R:L184	R:R:N187	4.12	Yes	Yes	2	8	9
682	R:R:F189	R:R:L184	6.09	Yes	Yes	2	8	8
683	R:R:L184	R:R:L207	5.54	Yes	No	0	8	7
684	R:R:Y185	R:R:Y206	13.9	Yes	Yes	1	7	6
685	R:R:N208	R:R:Y185	9.3	Yes	Yes	1	5	7
686	R:R:K209	R:R:N186	19.58	Yes	No	0	7	7
687	R:R:F189	R:R:N187	16.92	Yes	Yes	2	8	9
688	R:R:N187	R:R:N210	5.45	Yes	Yes	2	9	9
689	R:R:F189	R:R:N210	6.04	Yes	Yes	2	8	9
690	R:R:S191	R:R:T190	3.2	No	No	0	4	5
691	R:R:L213	R:R:V192	2.98	Yes	No	0	9	7
692	R:R:D217	R:R:G194	5.03	No	No	0	5	3
693	R:R:N198	R:R:Y195	3.49	Yes	No	0	7	4
694	R:R:D219	R:R:Y195	6.9	No	No	0	3	4
695	R:R:G222	R:R:Y195	4.35	No	No	0	3	4
696	R:R:F197	R:R:L202	4.87	Yes	Yes	0	9	8
697	R:R:F197	R:R:F221	12.86	Yes	Yes	12	9	9
698	R:R:G199	R:R:N198	3.39	No	Yes	21	7	7
699	R:R:G223	R:R:N198	3.39	No	Yes	0	7	7
700	R:R:G199	R:R:Y225	8.69	No	No	0	7	4
701	R:R:L202	R:R:T200	7.37	Yes	No	0	8	8
702	R:R:K201	R:R:Y225	4.78	No	No	0	4	4
703	R:R:L202	R:R:V205	5.96	Yes	Yes	0	8	7
704	R:R:L202	R:R:P228	6.57	Yes	Yes	0	8	8
705	R:R:A204	R:R:Y206	5.34	No	Yes	1	5	6
706	R:R:A204	R:R:L230	4.73	No	No	1	5	4
707	R:R:L207	R:R:V205	2.98	No	Yes	0	7	7
708	R:R:L231	R:R:V205	2.98	Yes	Yes	0	7	7
709	R:R:L230	R:R:Y206	8.21	No	Yes	1	4	6
710	R:R:D232	R:R:Y206	6.9	Yes	Yes	1	9	6
711	R:R:L207	R:R:N210	4.12	No	Yes	0	7	9
712	R:R:D232	R:R:N208	16.16	Yes	Yes	1	9	5
713	R:R:N208	R:R:S234	5.96	Yes	Yes	1	5	9
714	R:R:K209	R:R:Q235	4.07	Yes	No	1	7	4
715	R:R:L213	R:R:N210	4.12	Yes	Yes	2	9	9
716	R:R:K211	R:R:Y212	8.36	No	No	0	3	3
717	R:R:I216	R:R:L213	5.71	No	Yes	2	6	9
718	R:R:L213	R:R:V238	4.47	Yes	No	2	9	7
719	R:R:T214	R:R:V215	4.76	No	No	0	4	2
720	R:R:I216	R:R:V238	4.61	No	No	2	6	7
721	R:R:I216	R:R:P242	5.08	No	No	0	6	9
722	R:R:D219	R:R:K218	6.91	No	No	0	3	4
723	R:R:D219	R:R:K244	5.53	No	No	0	3	3
724	R:R:F221	R:R:P228	5.78	Yes	Yes	12	9	8
725	R:R:F221	R:R:P242	4.33	Yes	No	0	9	9
726	R:R:F221	R:R:L246	4.87	Yes	No	12	9	7
727	R:R:G222	R:R:K244	3.49	No	No	0	3	3
728	R:R:G227	R:R:S226	3.71	No	No	0	7	4
729	R:R:G227	R:R:P228	4.06	No	Yes	0	7	8
730	R:R:L246	R:R:P228	3.28	No	Yes	12	7	8
731	R:R:K250	R:R:S229	3.06	No	No	0	7	5
732	R:R:E251	R:R:L230	13.25	Yes	No	1	5	4
733	R:R:L231	R:R:V233	2.98	Yes	No	0	7	7
734	R:R:D232	R:R:S234	7.36	Yes	Yes	1	9	9
735	R:R:D232	R:R:I253	15.39	Yes	Yes	1	9	4
736	R:R:T236	R:R:V233	4.76	No	No	0	9	7
737	R:R:L241	R:R:V233	2.98	No	No	0	9	7
738	R:R:I253	R:R:S234	3.1	Yes	Yes	1	4	9
739	R:R:R255	R:R:S234	3.95	Yes	Yes	0	4	9
740	R:R:T236	R:R:V238	6.35	No	No	0	9	7
741	R:R:T236	R:R:T257	3.14	No	No	0	9	8
742	R:R:L241	R:R:L260	4.15	No	No	0	9	9
743	R:R:S243	R:R:S268	3.26	No	No	0	5	5
744	R:R:E247	R:R:G245	4.91	No	No	0	4	9
745	R:R:H248	R:R:H271	10.75	No	No	0	4	5
746	R:R:L249	R:R:L252	4.15	No	Yes	12	8	9
747	R:R:E251	R:R:I253	8.2	Yes	Yes	1	5	4
748	R:R:E251	R:R:R274	3.49	Yes	Yes	1	5	3
749	R:R:A254	R:R:T257	3.36	No	No	0	8	8
750	R:R:D276	R:R:R255	21.44	No	Yes	0	4	4
751	R:R:N256	R:R:W258	3.39	No	No	0	5	4
752	R:R:S278	R:R:W258	6.18	No	No	22	9	4
753	R:R:W258	R:R:Y279	13.5	No	Yes	22	4	9
754	R:R:L260	R:R:L263	4.15	No	No	0	9	8
755	R:R:K261	R:R:Y279	4.78	No	Yes	0	8	9
756	R:R:K262	R:R:N483	8.39	No	No	0	5	8
757	R:R:D487	R:R:K262	8.3	No	No	0	6	5
758	R:R:L263	R:R:P264	4.93	No	No	0	8	9
759	R:R:H282	R:R:L263	9	No	No	0	9	8
760	R:R:L265	R:R:L267	4.15	No	No	0	7	5
761	R:R:F269	R:R:L272	4.87	No	No	0	7	8
762	R:R:H271	R:R:L270	6.43	No	No	0	5	3
763	R:R:F286	R:R:L272	4.87	No	No	0	8	8
764	R:R:L272	R:R:M396	4.24	No	No	0	8	6
765	R:R:R274	R:R:T399	5.17	Yes	No	0	3	4
766	R:R:A275	R:R:L277	3.15	No	Yes	0	9	9
767	R:R:D276	R:R:T399	15.9	No	No	0	4	4
768	R:R:H282	R:R:L277	5.14	No	Yes	0	9	9
769	R:R:C398	R:R:L277	3.17	No	Yes	0	9	9
770	R:R:S278	R:R:Y279	3.82	No	Yes	22	9	9
771	R:R:H282	R:R:Y279	7.62	No	Yes	0	9	9
772	R:R:I486	R:R:Y279	12.09	No	Yes	0	8	9
773	R:R:A485	R:R:S281	3.42	No	No	0	9	9
774	R:R:I486	R:R:S281	3.1	No	No	0	8	9
775	R:R:C283	R:R:C398	7.28	No	No	24	9	9
776	R:R:C283	R:R:P400	3.77	No	Yes	24	9	9
777	R:R:C284	R:R:C408	7.28	No	No	0	9	9
778	R:R:A285	R:R:Y482	8.01	No	Yes	0	8	8
779	R:R:C398	R:R:P400	3.77	No	Yes	24	9	9
780	R:R:P400	R:R:T399	3.5	Yes	No	0	9	4
781	R:R:K401	R:R:S402	4.59	No	No	0	4	9
782	R:R:D403	R:R:F405	9.55	No	Yes	0	8	8
783	R:R:D403	R:R:N406	6.73	No	No	0	8	9
784	R:R:F405	R:R:K565	4.96	Yes	No	4	8	7
785	R:R:F405	R:R:V566	3.93	Yes	Yes	4	8	9
786	R:R:F405	R:R:M572	3.73	Yes	No	4	8	9
787	R:R:F405	W:W:?1	6.11	Yes	Yes	4	8	0
788	R:R:N406	R:R:Q489	7.92	No	No	0	9	9
789	R:R:E409	R:R:P407	3.14	No	No	4	9	9
790	R:R:P407	R:R:V656	7.07	No	Yes	4	9	7
791	R:R:P407	R:R:S657	3.56	No	No	4	9	8
792	R:R:E409	R:R:G413	4.91	No	No	0	9	9
793	R:R:E409	R:R:S657	10.06	No	No	4	9	8
794	R:R:D410	R:R:G413	3.35	No	No	0	9	9
795	R:R:D410	R:R:R418	11.91	No	Yes	7	9	9
796	R:R:D410	R:R:D474	3.99	No	Yes	7	9	9
797	R:R:I411	R:R:V473	3.07	Yes	No	7	8	8
798	R:R:D474	R:R:I411	5.6	Yes	Yes	7	9	8
799	R:R:I411	R:R:Y481	7.25	Yes	Yes	7	8	8
800	R:R:I411	R:R:S567	4.64	Yes	No	7	8	9
801	R:R:L417	R:R:M412	9.9	No	Yes	7	9	8
802	R:R:M412	R:R:V421	6.09	Yes	No	7	8	9
803	R:R:D474	R:R:M412	9.7	Yes	Yes	7	9	8
804	R:R:M412	R:R:V664	3.04	Yes	Yes	7	8	9
805	R:R:F416	R:R:Y414	8.25	No	No	0	6	4
806	R:R:I661	R:R:Y414	3.63	No	No	0	9	4
807	R:R:L417	R:R:V664	11.92	No	Yes	7	9	9
808	R:R:D474	R:R:R418	13.1	Yes	Yes	7	9	9
809	R:R:F423	R:R:I419	6.28	No	No	0	5	6
810	R:R:V420	R:R:V664	3.21	No	Yes	0	6	9
811	R:R:A471	R:R:V421	3.39	No	No	0	9	9
812	R:R:V421	R:R:V664	4.81	No	Yes	7	9	9
813	R:R:A471	R:R:W422	11.67	No	No	0	9	9
814	R:R:L475	R:R:W422	4.56	No	No	0	4	9
815	R:R:P668	R:R:V424	3.53	No	No	0	9	9
816	R:R:L426	R:R:S425	3	No	No	0	6	8
817	R:R:C672	R:R:L427	4.76	No	No	0	9	7
818	R:R:A428	R:R:S671	3.42	No	No	0	9	9
819	R:R:F461	R:R:L429	4.87	No	No	0	5	7
820	R:R:L429	R:R:L468	4.15	No	No	0	7	7
821	R:R:G431	R:R:L430	5.13	No	No	0	9	5
822	R:R:D460	R:R:N432	9.42	Yes	No	0	9	9
823	R:R:N432	R:R:P675	8.15	No	No	0	9	9
824	R:R:F434	R:R:I438	12.56	No	Yes	17	7	8
825	R:R:F434	R:R:F685	5.36	No	Yes	17	7	9
826	R:R:L439	R:R:V435	4.47	No	No	0	8	9
827	R:R:A457	R:R:V435	3.39	No	No	0	9	9
828	R:R:A679	R:R:V435	5.09	No	No	0	9	9
829	R:R:A457	R:R:L436	4.73	No	No	0	9	5
830	R:R:F685	R:R:I438	11.3	Yes	Yes	17	9	8
831	R:R:I438	R:R:V689	3.07	Yes	No	17	8	5
832	R:R:C454	R:R:L439	3.17	No	No	0	8	8
833	R:R:C454	R:R:L440	3.17	No	No	0	8	6
834	R:R:L692	R:R:T441	4.42	No	No	0	8	7
835	R:R:S442	R:R:Y444	3.82	No	Yes	14	8	7
836	R:R:R450	R:R:S442	6.59	No	No	14	9	8
837	R:R:D688	R:R:S442	5.89	Yes	No	14	9	8
838	R:R:H443	R:R:K695	5.24	No	No	0	5	8
839	R:R:R687	R:R:Y444	25.72	Yes	Yes	14	7	7
840	R:R:D688	R:R:Y444	6.9	Yes	Yes	14	9	7
841	R:R:I691	R:R:Y444	3.63	Yes	Yes	14	6	7
842	R:R:C454	R:R:L446	3.17	No	No	0	8	6
843	R:R:N447	R:R:P449	14.66	No	No	0	8	8
844	R:R:N447	R:R:R450	10.85	No	No	0	8	9
845	R:R:P449	R:R:V448	3.53	No	Yes	0	8	9
846	R:R:L452	R:R:V448	2.98	Yes	Yes	0	9	9
847	R:R:I533	R:R:V448	3.07	No	Yes	0	5	9
848	R:R:L535	R:R:V448	2.98	No	Yes	0	7	9
849	R:R:A538	R:R:V448	5.09	No	Yes	0	9	9
850	R:R:E518	R:R:P449	6.29	No	No	0	9	8
851	R:R:D688	R:R:R450	5.96	Yes	No	14	9	9
852	R:R:F451	R:R:L452	3.65	Yes	Yes	0	9	9
853	R:R:F451	R:R:N455	8.46	Yes	No	15	9	8
854	R:R:F451	R:R:L535	3.65	Yes	No	0	9	7
855	R:R:F451	R:R:M542	6.22	Yes	Yes	15	9	9
856	R:R:L452	R:R:V514	4.47	Yes	No	0	9	6
857	R:R:I515	R:R:L452	5.71	No	Yes	0	9	9
858	R:R:M453	R:R:Y678	4.79	No	Yes	0	7	9
859	R:R:M542	R:R:N455	18.23	Yes	No	15	9	8
860	R:R:N455	R:R:W546	5.65	No	Yes	0	8	9
861	R:R:D460	R:R:L456	8.14	Yes	Yes	13	9	9
862	R:R:L456	R:R:S508	3	Yes	No	13	9	9
863	R:R:L456	R:R:T511	5.9	Yes	No	0	9	9
864	R:R:L456	R:R:L512	4.15	Yes	No	0	9	9
865	R:R:L456	R:R:N674	8.24	Yes	Yes	13	9	9
866	R:R:C462	R:R:F458	5.59	No	No	0	7	7
867	R:R:F458	R:R:W546	10.02	No	Yes	0	7	9
868	R:R:A459	R:R:L507	4.73	No	No	0	9	9
869	R:R:D460	R:R:S508	5.89	Yes	No	13	9	9
870	R:R:D460	R:R:S671	4.42	Yes	No	0	9	9
871	R:R:D460	R:R:N674	8.08	Yes	Yes	13	9	9
872	R:R:F461	R:R:M465	3.73	No	No	0	5	4
873	R:R:M463	R:R:Y667	7.18	No	Yes	0	9	9
874	R:R:M463	R:R:S671	6.13	No	No	0	9	9
875	R:R:L467	R:R:Y466	3.52	No	Yes	0	9	9
876	R:R:I470	R:R:Y466	12.09	No	Yes	0	8	9
877	R:R:T501	R:R:Y466	14.98	No	Yes	0	9	9
878	R:R:L663	R:R:Y466	4.69	No	Yes	0	9	9
879	R:R:L467	R:R:P668	6.57	No	No	0	9	9
880	R:R:L469	R:R:V473	2.98	No	No	7	7	8
881	R:R:L469	R:R:W488	3.42	No	Yes	7	7	9
882	R:R:V473	R:R:W488	13.48	No	Yes	7	8	9
883	R:R:D474	R:R:L475	5.43	Yes	No	0	9	4
884	R:R:T477	R:R:Y476	4.99	No	No	0	9	5
885	R:R:T477	R:R:Y481	4.99	No	Yes	0	9	8
886	R:R:H484	R:R:T477	9.58	No	No	0	6	9
887	R:R:E480	R:R:Y482	6.73	No	Yes	23	6	8
888	R:R:E480	R:R:N483	11.83	No	No	23	6	8
889	R:R:E480	R:R:H484	7.39	No	No	0	6	6
890	R:R:A485	R:R:Y481	5.34	No	Yes	0	9	8
891	R:R:W488	R:R:Y481	6.75	Yes	Yes	7	9	8
892	R:R:Q489	R:R:Y481	9.02	No	Yes	0	9	8
893	R:R:S567	R:R:Y481	6.36	No	Yes	7	9	8
894	R:R:N483	R:R:Y482	12.79	No	Yes	23	8	8
895	R:R:I486	R:R:T490	3.04	No	No	0	8	8
896	R:R:G493	R:R:W488	4.22	No	Yes	0	9	9
897	R:R:C494	R:R:W488	3.92	No	Yes	7	9	9
898	R:R:C569	R:R:W488	5.22	No	Yes	7	9	9
899	R:R:G491	R:R:P492	4.06	No	No	0	8	3
900	R:R:G493	R:R:T496	3.64	No	No	0	9	5
901	R:R:C494	R:R:C569	7.28	No	No	7	9	9
902	R:R:L557	R:R:N495	4.12	No	No	4	7	5
903	R:R:N495	R:R:Y563	3.49	No	Yes	4	5	9
904	R:R:F500	R:R:T496	3.89	No	No	0	7	5
905	R:R:A497	R:R:C569	3.61	No	No	0	9	9
906	R:R:G498	R:R:Y563	10.14	No	Yes	0	9	9
907	R:R:F499	R:R:F550	9.65	No	No	0	8	4
908	R:R:A553	R:R:F499	8.32	No	No	0	9	8
909	R:R:L570	R:R:T501	4.42	Yes	No	4	9	9
910	R:R:T501	R:R:Y667	4.99	No	Yes	4	9	9
911	R:R:A553	R:R:V502	3.39	No	Yes	0	9	9
912	R:R:V502	R:R:Y563	6.31	Yes	Yes	4	9	9
913	R:R:P571	R:R:V502	3.53	Yes	Yes	4	9	9
914	R:R:V502	R:R:Y582	3.79	Yes	Yes	4	9	9
915	R:R:F503	R:R:W546	4.01	No	Yes	0	9	9
916	R:R:E506	R:R:S505	5.75	Yes	No	0	8	9
917	R:R:S505	R:R:Y667	6.36	No	Yes	4	9	9
918	R:R:S505	W:W:?1	3.23	No	Yes	4	9	0
919	R:R:C549	R:R:E506	3.04	No	Yes	0	8	8
920	R:R:E506	R:R:V586	5.7	Yes	No	0	8	7
921	R:R:E506	R:R:N590	11.83	Yes	No	0	8	9
922	R:R:L507	R:R:W546	11.39	No	Yes	0	9	9
923	R:R:C549	R:R:L507	3.17	No	No	0	8	9
924	R:R:N590	R:R:V509	5.91	No	No	0	9	8
925	R:R:V514	R:R:Y510	5.05	No	Yes	15	6	7
926	R:R:I541	R:R:Y510	4.84	No	Yes	15	7	7
927	R:R:M542	R:R:Y510	3.59	Yes	Yes	15	9	7
928	R:R:G545	R:R:Y510	10.14	No	Yes	0	9	7
929	R:R:M542	R:R:T511	6.02	Yes	No	0	9	9
930	R:R:D633	R:R:L512	5.43	Yes	No	0	8	9
931	R:R:L512	R:R:Y678	7.03	No	Yes	0	9	9
932	R:R:A593	R:R:T513	3.36	No	No	0	9	9
933	R:R:I596	R:R:T513	3.04	No	No	0	6	9
934	R:R:I541	R:R:V514	3.07	No	No	15	7	6
935	R:R:T516	R:R:V597	14.28	No	No	0	9	9
936	R:R:C600	R:R:T516	5.07	No	No	0	9	9
937	R:R:T516	R:R:Y601	13.73	No	Yes	0	9	9
938	R:R:I596	R:R:L517	4.28	No	No	0	6	5
939	R:R:C600	R:R:L517	3.17	No	No	0	9	5
940	R:R:R519	R:R:Y601	8.23	No	Yes	0	9	9
941	R:R:R519	R:R:Y678	5.14	No	Yes	0	9	9
942	R:R:T524	R:R:W520	9.7	No	Yes	0	8	7
943	R:R:C600	R:R:W520	5.22	No	Yes	0	9	7
944	R:R:K603	R:R:W520	4.64	No	Yes	0	7	7
945	R:R:I604	R:R:W520	4.7	No	Yes	0	9	7
946	R:R:F525	R:R:Y521	15.47	No	No	0	6	6
947	R:R:R531	R:R:Y521	4.12	No	No	0	7	6
948	R:R:I533	R:R:Y521	12.09	No	No	0	5	6
949	R:R:I523	R:R:I604	8.83	No	No	25	9	9
950	R:R:F525	R:R:T524	9.08	No	No	0	6	8
951	R:R:F525	R:R:R528	6.41	No	No	0	6	7
952	R:R:R528	R:R:R531	11.73	No	No	0	7	7
953	R:R:R534	R:R:R536	8.53	No	No	0	7	5
954	R:R:H537	R:R:R534	6.77	No	No	0	7	7
955	R:R:F550	R:R:L554	3.65	No	No	0	4	5
956	R:R:L552	R:R:Y582	4.69	No	Yes	0	7	9
957	R:R:L554	R:R:L557	4.15	No	No	0	5	7
958	R:R:I560	R:R:L555	12.85	No	No	4	7	7
959	R:R:L555	R:R:Y582	3.52	No	Yes	4	7	9
960	R:R:P556	R:R:Y563	16.69	No	Yes	0	9	9
961	R:R:P556	R:R:Y582	11.13	No	Yes	0	9	9
962	R:R:L557	R:R:Y563	3.52	No	Yes	4	7	9
963	R:R:I560	R:R:Y582	3.63	No	Yes	4	7	9
964	R:R:A579	R:R:S561	3.42	No	No	0	8	9
965	R:R:I583	R:R:S561	3.1	No	No	0	7	9
966	R:R:D573	R:R:S562	4.42	Yes	No	0	8	8
967	R:R:P571	R:R:Y563	8.34	Yes	Yes	4	9	9
968	R:R:D573	R:R:K565	8.3	Yes	No	4	8	7
969	R:R:E575	R:R:K565	5.4	No	No	4	4	7
970	R:R:I568	R:R:V566	3.07	No	Yes	0	9	9
971	R:R:M572	R:R:V566	6.09	No	Yes	4	9	9
972	R:R:V566	R:R:V656	3.21	Yes	Yes	4	9	7
973	R:R:K660	R:R:S567	3.06	No	No	0	9	9
974	R:R:I568	R:R:L570	5.71	No	Yes	0	9	9
975	R:R:I568	R:R:L663	5.71	No	No	0	9	9
976	R:R:L570	R:R:P571	4.93	Yes	Yes	4	9	9
977	R:R:L570	R:R:Y667	3.52	Yes	Yes	4	9	9
978	R:R:L570	W:W:?1	9.93	Yes	Yes	4	9	0
979	R:R:P571	W:W:?1	4.71	Yes	Yes	4	9	0
980	R:R:M572	W:W:?1	15.21	No	Yes	4	9	0
981	R:R:D573	R:R:E575	9.09	Yes	No	4	8	4
982	R:R:T574	W:W:?1	12.68	No	Yes	0	6	0
983	R:R:P577	R:R:T576	3.5	No	No	0	3	6
984	R:R:L580	R:R:V584	2.98	No	No	0	4	5
985	R:R:I648	R:R:L580	4.28	No	No	0	6	4
986	R:R:V586	R:R:Y582	6.31	No	Yes	0	7	9
987	R:R:A644	R:R:L587	3.15	No	No	4	9	8
988	R:R:L587	R:R:L645	5.54	No	No	0	8	7
989	R:R:L587	W:W:?1	2.98	No	Yes	4	8	0
990	R:R:I591	R:R:S641	6.19	No	No	0	6	9
991	R:R:C598	R:R:F594	6.98	No	Yes	0	7	8
992	R:R:D633	R:R:F594	10.75	Yes	Yes	0	8	8
993	R:R:F594	R:R:F634	8.57	Yes	No	0	8	9
994	R:R:F594	R:R:M637	4.98	Yes	No	0	8	7
995	R:R:D633	R:R:V597	4.38	Yes	No	0	8	9
996	R:R:C598	R:R:I630	3.27	No	No	0	7	9
997	R:R:M626	R:R:Y601	9.58	No	Yes	0	9	9
998	R:R:L629	R:R:Y601	3.52	No	Yes	0	9	9
999	R:R:I630	R:R:Y601	4.84	No	Yes	0	9	9
1000	R:R:R609	R:R:Y605	8.23	No	Yes	26	7	9
1001	R:R:D619	R:R:Y605	3.45	No	Yes	26	9	9
1002	R:R:I622	R:R:Y605	4.84	No	Yes	0	8	9
1003	R:R:A623	R:R:Y605	4	No	Yes	0	9	9
1004	R:R:M626	R:R:Y605	4.79	No	Yes	0	9	9
1005	R:R:D619	R:R:R609	8.34	No	No	26	9	7
1006	R:R:D619	R:R:N610	6.73	No	No	0	9	6
1007	R:R:K624	R:R:T620	3	No	No	0	9	7
1008	R:R:K621	R:R:R625	3.71	No	No	0	6	9
1009	R:R:L629	R:R:L677	5.54	No	Yes	13	9	9
1010	R:R:L629	R:R:Y678	9.38	No	Yes	13	9	9
1011	R:R:F631	R:R:I635	13.82	No	No	0	8	6
1012	R:R:L677	R:R:T632	4.42	Yes	No	0	9	9
1013	R:R:D633	R:R:N670	4.04	Yes	No	0	8	9
1014	R:R:A638	R:R:F634	8.32	No	No	0	8	9
1015	R:R:C636	R:R:L669	6.35	No	No	0	9	8
1016	R:R:C636	R:R:N670	12.6	No	No	0	9	9
1017	R:R:M637	R:R:S641	4.6	No	No	0	7	9
1018	R:R:I640	R:R:P639	3.39	No	No	0	9	9
1019	R:R:I640	R:R:Y667	4.84	No	Yes	4	9	9
1020	R:R:I640	W:W:?1	14.33	No	Yes	4	9	0
1021	R:R:F642	R:R:Y643	3.09	No	No	0	9	8
1022	R:R:I654	R:R:Y643	12.09	No	No	0	9	8
1023	R:R:L662	R:R:Y643	5.86	No	No	0	8	8
1024	R:R:A644	W:W:?1	6.78	No	Yes	4	9	0
1025	R:R:A647	R:R:P652	3.74	No	No	4	9	9
1026	R:R:A647	W:W:?1	6.78	No	Yes	4	9	0
1027	R:R:P652	W:W:?1	5.89	No	Yes	4	9	0
1028	R:R:I654	R:R:N658	4.25	No	No	0	9	8
1029	R:R:I654	W:W:?1	10.23	No	Yes	0	9	0
1030	R:R:N658	R:R:T655	5.85	No	No	0	8	8
1031	R:R:S659	R:R:V656	3.23	No	Yes	4	9	7
1032	R:R:V656	W:W:?1	5.34	Yes	Yes	4	7	0
1033	R:R:S659	W:W:?1	11.84	No	Yes	4	9	0
1034	R:R:F666	R:R:L662	3.65	No	No	0	8	8
1035	R:R:L662	W:W:?1	6.95	No	Yes	0	8	0
1036	R:R:L665	R:R:V664	2.98	No	Yes	0	8	9
1037	R:R:F666	R:R:L665	3.65	No	No	0	8	8
1038	R:R:P668	R:R:Y667	4.17	No	Yes	0	9	9
1039	R:R:Y667	W:W:?1	9.25	Yes	Yes	4	9	0
1040	R:R:N670	R:R:N674	12.26	No	Yes	0	9	9
1041	R:R:N674	R:R:Y678	3.49	Yes	Yes	13	9	9
1042	R:R:F676	R:R:I680	7.54	No	No	0	8	9
1043	R:R:L677	R:R:Y678	4.69	Yes	Yes	13	9	9
1044	R:R:A679	R:R:F685	4.16	No	Yes	0	9	9
1045	R:R:F685	R:R:I680	6.28	Yes	No	0	9	9
1046	R:R:F685	R:R:T682	3.89	Yes	No	0	9	9
1047	R:R:K683	R:R:Q686	4.07	No	No	0	8	7
1048	R:R:A684	R:R:R687	4.15	No	Yes	0	8	7
1049	R:R:F685	R:R:V689	3.93	Yes	No	17	9	5
1050	R:R:F690	R:R:Q686	5.86	No	No	0	5	7
1051	R:R:D688	R:R:R687	13.1	Yes	Yes	14	9	7
1052	R:R:I691	R:R:R687	3.76	Yes	Yes	14	6	7
1053	R:R:I698	R:R:L693	4.28	No	No	0	3	7
1054	M:M:L95	M:M:T2	2.95	Yes	No	3	0	0
1055	M:M:L99	M:M:T2	2.95	Yes	No	3	0	0
1056	R:R:L437	R:R:T441	2.95	No	No	0	3	7
1057	R:R:L580	R:R:T574	2.95	No	No	0	4	6
1058	R:R:D203	R:R:S229	2.94	No	No	0	6	5
1059	R:R:D573	R:R:S561	2.94	Yes	No	0	8	9
1060	L:L:N207	L:L:T159	2.92	No	No	0	0	0
1061	L:L:Q82	L:L:S17	2.89	No	No	0	0	0
1062	L:L:F174	L:L:P175	2.89	Yes	No	0	0	0
1063	R:R:D86	R:R:T88	2.89	Yes	No	0	8	4
1064	R:R:D203	R:R:T179	2.89	No	No	0	6	5
1065	R:R:D203	R:R:T181	2.89	No	No	0	6	7
1066	R:R:P48	R:R:R46	2.88	Yes	No	0	9	1
1067	M:M:E126	M:M:S125	2.87	No	No	0	0	0
1068	L:L:S180	M:M:E163	2.87	No	No	0	0	0
1069	R:R:I635	R:R:L669	2.85	No	No	0	6	8
1070	R:R:I661	R:R:L665	2.85	No	No	0	9	8
1071	R:R:L439	R:R:M453	2.83	No	No	0	8	7
1072	R:R:H70	R:R:S73	2.79	No	No	0	4	4
1073	R:R:H478	R:R:S479	2.79	No	No	0	5	7
1074	M:M:L4	M:M:L99	2.77	Yes	Yes	3	0	0
1075	M:M:D154	M:M:K192	2.77	No	No	0	0	0
1076	L:L:F174	M:M:A176	2.77	Yes	No	0	0	0
1077	R:R:D43	R:R:K42	2.77	No	No	0	4	2
1078	R:R:L122	R:R:L125	2.77	No	Yes	0	7	8
1079	R:R:A220	R:R:F197	2.77	No	Yes	12	8	9
1080	R:R:D217	R:R:K218	2.77	No	No	0	5	4
1081	R:R:A220	R:R:F221	2.77	No	Yes	12	8	9
1082	R:R:L231	R:R:L249	2.77	Yes	No	12	7	8
1083	R:R:L231	R:R:L252	2.77	Yes	Yes	12	7	9
1084	R:R:L241	R:R:L252	2.77	No	Yes	0	9	9
1085	R:R:L246	R:R:L249	2.77	No	No	12	7	8
1086	R:R:L252	R:R:L277	2.77	Yes	Yes	0	9	9
1087	R:R:A275	R:R:F286	2.77	No	No	0	9	8
1088	R:R:E61	R:R:I85	2.73	No	No	0	5	6
1089	R:R:E124	R:R:K123	2.7	No	No	0	4	4
1090	L:L:F130	L:L:S128	2.64	Yes	No	0	0	0
1091	R:R:F286	R:R:S266	2.64	No	No	0	8	5
1092	R:R:F269	R:R:S268	2.64	No	No	0	7	5
1093	R:R:E178	R:R:N177	2.63	No	No	0	5	5
1094	L:L:H67	L:L:K87	2.62	No	No	0	0	0
1095	R:R:R274	R:R:T273	2.59	Yes	No	0	3	4
1096	R:R:F681	R:R:I680	2.51	No	No	0	8	9
1097	L:L:T69	L:L:Y60	2.5	No	Yes	0	0	0
1098	R:R:F500	R:R:M465	2.49	No	No	0	7	4
1099	R:R:K415	R:R:R418	2.48	No	Yes	0	3	9
1100	R:R:F676	R:R:L427	2.44	No	No	0	8	7
1101	R:R:F585	R:R:L552	2.44	No	No	0	4	7
1102	M:M:D60	M:M:R76	2.38	No	No	0	0	0
1103	M:M:L109	M:M:Y143	2.34	No	Yes	0	0	0
1104	R:R:L426	R:R:W422	2.28	No	No	0	6	9
1105	L:L:F174	L:L:H172	2.26	Yes	No	0	0	0
1106	R:R:H478	R:R:R418	2.26	No	Yes	0	5	9
1107	M:M:R61	M:M:R76	2.13	Yes	No	0	0	0
1108	M:M:G101	M:M:G102	2.11	No	No	0	0	0
1109	M:M:G102	M:M:G103	2.11	No	No	0	0	0
1110	R:R:G544	R:R:G545	2.11	No	No	0	3	9
1111	M:M:P7	M:M:P8	1.95	Yes	No	0	0	0
1112	R:R:P51	R:R:P52	1.95	Yes	No	0	5	3
1113	R:R:P280	R:R:P400	1.95	No	Yes	0	8	9
1114	R:R:A428	R:R:G464	1.95	No	No	0	9	9
1115	M:M:A14	M:M:P15	1.87	No	No	0	0	0
1116	M:M:A84	M:M:P40	1.87	Yes	No	0	0	0
1117	M:M:A115	M:M:P116	1.87	No	Yes	0	0	0
1118	M:M:A210	M:M:P211	1.87	No	No	0	0	0
1119	L:L:A133	L:L:P134	1.87	No	Yes	0	0	0
1120	L:L:A144	L:L:P134	1.87	No	Yes	0	0	0
1121	M:M:G13	M:M:S12	1.86	No	No	0	0	0
1122	M:M:G64	M:M:S65	1.86	No	No	0	0	0
1123	L:L:G8	L:L:S7	1.86	No	No	0	0	0
1124	L:L:G15	L:L:S85	1.86	No	No	0	0	0
1125	L:L:G142	L:L:S194	1.86	No	No	0	0	0
1126	L:L:G165	L:L:S161	1.86	No	No	0	0	0
1127	L:L:G170	L:L:S169	1.86	No	No	0	0	0
1128	R:R:G544	R:R:V543	1.84	No	No	0	3	3
1129	R:R:G544	R:R:V547	1.84	No	No	0	3	3
1130	R:R:G559	R:R:V558	1.84	No	No	0	9	4
1131	M:M:G29	M:M:T69	1.82	No	No	0	0	0
1132	M:M:G202	M:M:T199	1.82	No	No	0	0	0
1133	R:R:G491	R:R:T490	1.82	No	No	0	8	8
1134	R:R:A504	R:R:C462	1.81	No	No	0	8	7
1135	M:M:P157	M:M:S156	1.78	No	No	0	0	0
1136	L:L:P14	L:L:S120	1.78	No	No	0	0	0
1137	L:L:P193	L:L:S195	1.78	No	No	0	0	0
1138	R:R:P126	R:R:S101	1.78	No	No	0	5	4
1139	M:M:P116	M:M:V205	1.77	Yes	No	0	0	0
1140	R:R:P126	R:R:T150	1.75	No	No	0	5	3
1141	M:M:G110	M:M:K113	1.74	No	No	0	0	0
1142	R:R:C408	R:R:S402	1.72	No	No	0	9	9
1143	M:M:G13	M:M:L78	1.71	No	No	0	0	0
1144	M:M:A74	M:M:S63	1.71	No	No	0	0	0
1145	M:M:G64	M:M:L73	1.71	No	No	0	0	0
1146	M:M:G161	M:M:L181	1.71	No	Yes	0	0	0
1147	L:L:G182	L:L:L178	1.71	No	No	0	0	0
1148	L:L:G198	L:L:L197	1.71	No	Yes	0	0	0
1149	R:R:A121	R:R:S96	1.71	No	No	0	9	7
1150	R:R:C539	R:R:V543	1.71	No	No	0	4	3
1151	R:R:A564	R:R:S562	1.71	No	No	0	7	8
1152	R:R:C599	R:R:V595	1.71	No	No	0	4	3
1153	R:R:G188	R:R:N187	1.7	No	Yes	0	6	9
1154	L:L:A145	M:M:T119	1.68	No	No	0	0	0
1155	M:M:A177	M:M:T165	1.68	No	No	0	0	0
1156	L:L:A145	L:L:T191	1.68	No	No	0	0	0
1157	R:R:A240	R:R:T239	1.68	No	No	0	5	4
1158	R:R:A579	R:R:T576	1.68	No	No	0	8	6
1159	R:R:A673	R:R:T632	1.68	No	No	0	9	9
1160	L:L:K209	L:L:P210	1.67	No	No	0	0	0
1161	R:R:L75	R:R:P76	1.64	No	No	0	6	5
1162	R:R:L125	R:R:P126	1.64	Yes	No	0	8	5
1163	R:R:G194	R:R:Q193	1.64	No	No	0	3	5
1164	R:R:L578	R:R:P577	1.64	No	No	0	3	3
1165	M:M:S24	M:M:S70	1.63	No	No	0	0	0
1166	M:M:S67	M:M:S70	1.63	No	No	0	0	0
1167	M:M:S117	M:M:S140	1.63	No	No	0	0	0
1168	L:L:S84	L:L:S85	1.63	No	No	0	0	0
1169	R:R:N77	R:R:P76	1.63	No	No	0	8	5
1170	R:R:N161	R:R:P162	1.63	Yes	No	0	8	7
1171	R:R:S166	R:R:S191	1.63	No	No	0	5	4
1172	L:L:S135	M:M:V209	1.62	No	No	0	0	0
1173	R:R:S191	R:R:V215	1.62	No	No	0	4	2
1174	R:R:C408	R:R:K287	1.62	No	No	0	9	5
1175	R:R:A526	R:R:M527	1.61	No	No	0	9	8
1176	M:M:S70	M:M:T69	1.6	No	No	0	0	0
1177	L:L:S123	L:L:T124	1.6	No	No	0	0	0
1178	R:R:S237	R:R:T259	1.6	No	No	0	4	5
1179	L:L:G170	L:L:H172	1.59	No	No	0	0	0
1180	R:R:T88	R:R:V87	1.59	No	No	0	4	4
1181	R:R:T200	R:R:V224	1.59	No	No	0	8	7
1182	R:R:T588	R:R:V584	1.59	No	No	0	3	5
1183	R:R:T588	R:R:V592	1.59	No	No	0	3	3
1184	M:M:P112	M:M:Q111	1.58	No	No	0	0	0
1185	R:R:P168	R:R:Q193	1.58	Yes	No	0	6	5
1186	R:R:A581	R:R:L578	1.58	No	No	0	4	3
1187	R:R:T239	R:R:T259	1.57	No	No	0	4	5
1188	R:R:T524	R:R:T607	1.57	No	No	0	8	7
1189	L:L:A166	L:L:N163	1.56	No	No	0	0	0
1190	L:L:I51	L:L:S56	1.55	Yes	No	0	0	0
1191	R:R:I523	R:R:V608	1.54	No	No	25	9	9
1192	R:R:I560	R:R:V558	1.54	No	No	0	7	4
1193	R:R:I591	R:R:V595	1.54	No	No	0	6	3
1194	R:R:I606	R:R:V602	1.54	No	No	0	3	4
1195	R:R:I604	R:R:V608	1.54	No	No	25	9	9
1196	R:R:K651	R:R:S646	1.53	No	No	0	4	9
1197	R:R:C176	R:R:E178	1.52	No	No	0	6	5
1198	R:R:F221	R:R:G245	1.51	Yes	No	0	9	9
1199	R:R:F434	R:R:G431	1.51	No	No	0	7	9
1200	R:R:A522	R:R:E518	1.51	No	No	0	8	9
1201	M:M:G57	R:R:R255	1.5	No	Yes	0	0	4
1202	L:L:L197	L:L:S194	1.5	Yes	No	0	0	0
1203	R:R:L265	R:R:S268	1.5	No	No	0	7	5
1204	R:R:L653	R:R:S646	1.5	No	No	0	9	9
1205	L:L:N205	L:L:S161	1.49	No	No	0	0	0
1206	R:R:L589	R:R:V509	1.49	No	No	0	3	8
1207	R:R:L551	R:R:V547	1.49	No	No	0	2	3
1208	R:R:L677	R:R:V628	1.49	Yes	No	0	9	6
1209	R:R:L693	R:R:V689	1.49	No	No	0	7	5
1210	M:M:D154	M:M:S155	1.47	No	No	0	0	0
1211	R:R:L127	R:R:T104	1.47	No	No	0	4	5
1212	R:R:I691	R:R:K695	1.45	Yes	No	0	6	8
1213	L:L:Q3	L:L:S25	1.44	No	No	0	0	0
1214	L:L:Q113	L:L:V5	1.43	No	No	0	0	0
1215	R:R:I438	R:R:L437	1.43	Yes	No	0	8	3
1216	R:R:I691	R:R:L692	1.43	Yes	No	0	6	8
1217	R:R:E30	R:R:T40	1.41	No	Yes	0	3	8
1218	R:R:K532	R:R:L529	1.41	No	No	0	8	8
1219	R:R:K651	R:R:L649	1.41	No	No	0	4	5
1220	L:L:D216	L:L:I203	1.4	No	No	0	0	0
1221	R:R:D151	R:R:I152	1.4	No	No	0	4	3
1222	M:M:H191	M:M:S190	1.39	Yes	No	0	0	0
1223	R:R:C284	R:R:Y482	1.34	No	Yes	0	9	8
1224	R:R:H537	R:R:I533	1.33	No	No	0	7	5
1225	M:M:R105	M:M:S9	1.32	No	No	0	0	0
1226	R:R:H271	R:R:K250	1.31	No	No	0	5	7
1227	R:R:F696	R:R:I698	1.26	No	No	0	4	3
1228	R:R:T115	R:R:Y116	1.25	No	Yes	0	4	3
1229	R:R:T190	R:R:Y212	1.25	No	No	0	5	3
1230	R:R:F141	R:R:M140	1.24	Yes	No	0	7	1
1231	R:R:F690	R:R:L693	1.22	No	No	0	5	7
1232	R:R:K139	R:R:Y163	1.19	No	No	0	4	4
1233	R:R:K146	R:R:Y148	1.19	Yes	No	0	4	4
1234	R:R:Q90	R:R:R65	1.17	No	No	0	4	4
1235	R:R:E404	W:W:?1	0.95	No	Yes	0	7	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	M:M:L4	4.484	5	3	0
2	M:M:Q6	5.8	5	3	0
3	M:M:P7	3.73667	6	3	0
4	M:M:V11	4.116	5	3	0
5	M:M:V19	3.805	4	3	0
6	M:M:I28	4.698	5	3	0
7	M:M:N31	6.968	5	1	0
8	M:M:W35	7.476	5	3	0
9	M:M:Y36	6.1925	4	1	0
10	M:M:Q37	8.046	5	3	0
11	M:M:Q38	8.065	4	1	0
12	M:M:L46	6.9925	4	1	0
13	M:M:Y49	11.7017	6	1	0
14	M:M:Y50	4.684	5	1	0
15	M:M:Q53	8.13	4	1	0
16	M:M:R61	6.72571	7	3	0
17	M:M:F62	6.116	5	3	0
18	M:M:I75	5.8	4	3	0
19	M:M:D82	6.646	5	3	0
20	M:M:A84	3.4075	4	3	0
21	M:M:Y86	6.84	4	3	0
22	M:M:Y87	6.285	6	1	0
23	M:M:C88	5.335	4	3	0
24	M:M:T89	8.78	4	1	0
25	M:M:W91	6.57	6	1	0
26	M:M:L95	4.2575	4	3	0
27	M:M:Q98	10.9	5	1	0
28	M:M:L99	3.825	4	3	0
29	M:M:F100	11.53	4	1	0
30	M:M:T104	7.6175	4	3	0
31	M:M:P116	4.235	6	5	0
32	M:M:F121	5.6075	4	6	0
33	M:M:P123	9.9625	4	5	0
34	M:M:E127	8.396	5	6	0
35	M:M:T134	7.21	4	0	0
36	M:M:L135	6.35667	6	5	0
37	M:M:V136	5.93167	6	6	0
38	M:M:L138	5.986	5	6	0
39	M:M:F142	8.332	5	5	0
40	M:M:Y143	5.97	5	0	0
41	M:M:W151	10.258	5	5	0
42	M:M:Q170	5.744	5	16	0
43	M:M:Y175	7.605	4	5	0
44	M:M:Y180	5.85833	6	6	0
45	M:M:L181	7.904	5	5	0
46	M:M:L183	8.1875	4	5	0
47	M:M:W188	9.49333	6	5	0
48	M:M:H191	6.262	5	5	0
49	M:M:Y194	8.364	5	5	0
50	M:M:V198	4.4075	4	5	0
51	M:M:H200	5.75333	6	5	0
52	L:L:Q6	5.94833	6	8	0
53	L:L:L18	6.372	5	8	0
54	L:L:I20	5.19	4	8	0
55	L:L:Y27	9.35	4	1	0
56	L:L:R28	8.324	5	1	0
57	L:L:F29	8.562	5	0	0
58	L:L:Y32	8.42	4	1	0
59	L:L:N35	7.7625	4	1	0
60	L:L:W36	7.82	5	8	0
61	L:L:V37	4.8275	4	1	0
62	L:L:R38	11.205	4	0	0
63	L:L:Q39	7.695	4	1	0
64	L:L:L45	9.17	4	1	0
65	L:L:W47	7.87143	7	1	0
66	L:L:M48	5.466	5	8	0
67	L:L:R50	12.888	5	1	0
68	L:L:I51	3.8975	4	0	0
69	L:L:D52	6.664	5	1	0
70	L:L:T54	7.435	4	1	0
71	L:L:D55	6.58	4	1	0
72	L:L:Y57	8.41222	9	1	0
73	L:L:Y60	5.882	5	19	0
74	L:L:I76	6.1675	4	10	0
75	L:L:Y80	8.6025	4	10	0
76	L:L:L81	8.828	5	8	0
77	L:L:W83	9.09	6	8	0
78	L:L:Y94	9.7475	4	0	0
79	L:L:Y95	7.17667	6	1	0
80	L:L:C96	7.26	4	8	0
81	L:L:R98	10.44	5	1	0
82	L:L:L99	6.1375	4	0	0
83	L:L:E100	6.16667	6	1	0
84	L:L:Y103	8.29375	8	1	0
85	L:L:W107	10.3429	7	1	0
86	L:L:S108	5.175	4	1	0
87	L:L:W111	8.485	6	1	0
88	L:L:P127	5.625	4	9	0
89	L:L:V129	4.3975	4	0	0
90	L:L:F130	5.825	4	6	0
91	L:L:P131	7.45	4	0	0
92	L:L:L132	6.392	5	6	0
93	L:L:P134	3.3975	4	0	0
94	L:L:L146	5.718	5	11	0
95	L:L:L149	5.34667	6	6	0
96	L:L:K151	7.84333	6	6	0
97	L:L:D152	5.845	4	6	0
98	L:L:Y153	8.66667	6	9	0
99	L:L:P155	8.164	5	9	0
100	L:L:E156	8.95	4	9	0
101	L:L:W162	7.088	5	11	0
102	L:L:F174	5.806	5	0	0
103	L:L:Q179	8.2125	4	6	0
104	L:L:Y184	11.6075	4	9	0
105	L:L:S187	4.828	5	6	0
106	L:L:V190	6.1025	4	11	0
107	L:L:S196	3.7275	4	11	0
108	L:L:L197	2.55	5	0	0
109	L:L:Y202	7.5925	4	11	0
110	L:L:H208	8.578	5	9	0
111	R:R:V39	4.355	4	2	6
112	R:R:T40	3.74	4	0	8
113	R:R:P48	4.6725	4	0	9
114	R:R:L50	4.745	4	2	5
115	R:R:P51	3.915	4	2	5
116	R:R:L57	4.396	5	2	7
117	R:R:K58	6.6525	4	1	5
118	R:R:I67	4.2875	4	2	5
119	R:R:F72	5.54	5	2	9
120	R:R:R80	12.7167	6	1	4
121	R:R:I81	4.7525	4	2	8
122	R:R:Y82	9.918	5	1	4
123	R:R:D86	5.9675	4	2	8
124	R:R:L92	4.25	5	2	8
125	R:R:F97	6.064	5	2	9
126	R:R:H105	7.775	6	1	7
127	R:R:E107	6.37833	6	1	6
128	R:R:R109	10.714	5	1	5
129	R:R:Y116	5.0675	4	20	3
130	R:R:L125	3.9225	4	2	8
131	R:R:L128	4.93	5	2	9
132	R:R:K129	8.514	5	1	5
133	R:R:F130	4.94429	7	1	6
134	R:R:F134	8.39	6	1	5
135	R:R:T136	5.345	6	2	9
136	R:R:L138	5.92	4	2	8
137	R:R:F141	5.43375	8	2	7
138	R:R:P142	4.78429	7	2	9
139	R:R:L144	5.2575	4	2	7
140	R:R:K146	4.6	4	0	4
141	R:R:F153	6.0425	4	0	5
142	R:R:F154	5.435	6	2	6
143	R:R:I155	4.375	4	1	5
144	R:R:L156	4.648	5	2	7
145	R:R:E157	9.712	5	1	8
146	R:R:I158	4.985	6	2	7
147	R:R:T159	7.1075	4	1	5
148	R:R:N161	5.11	5	2	8
149	R:R:M164	5.658	5	2	7
150	R:R:I167	4.94	4	0	7
151	R:R:P168	3.6225	4	0	6
152	R:R:F172	6.6575	4	0	8
153	R:R:L175	6.3625	4	2	7
154	R:R:K183	6.4775	4	1	6
155	R:R:L184	5.0075	4	2	8
156	R:R:Y185	8.15833	6	1	7
157	R:R:N187	7.01333	6	2	9
158	R:R:F189	8.68333	6	2	8
159	R:R:F197	6.1975	4	12	9
160	R:R:N198	5.81	5	21	7
161	R:R:L202	6.1925	4	0	8
162	R:R:V205	4.0975	4	0	7
163	R:R:Y206	7.586	5	1	6
164	R:R:N208	9.175	4	1	5
165	R:R:K209	9.6625	4	1	7
166	R:R:N210	4.9325	4	2	9
167	R:R:L213	4.32	4	2	9
168	R:R:F221	5.35333	6	12	9
169	R:R:P228	4.9225	4	12	8
170	R:R:L231	2.875	4	12	7
171	R:R:D232	11.4525	4	1	9
172	R:R:S234	5.0925	4	1	9
173	R:R:E251	7.3125	4	1	5
174	R:R:L252	3.115	4	12	9
175	R:R:I253	7.4475	4	1	4
176	R:R:R255	9.76	4	0	4
177	R:R:R274	3.8	4	1	3
178	R:R:L277	3.5575	4	0	9
179	R:R:Y279	8.362	5	22	9
180	R:R:P400	3.2475	4	24	9
181	R:R:F405	5.656	5	4	8
182	R:R:I411	5.14	4	7	8
183	R:R:M412	7.1825	4	7	8
184	R:R:R418	7.4375	4	7	9
185	R:R:I438	7.09	4	17	8
186	R:R:Y444	10.0175	4	14	7
187	R:R:V448	3.53	5	0	9
188	R:R:F451	5.495	4	15	9
189	R:R:L452	4.2025	4	0	9
190	R:R:L456	5.886	5	13	9
191	R:R:D460	7.19	5	13	9
192	R:R:Y466	8.82	4	0	9
193	R:R:D474	7.564	5	7	9
194	R:R:Y481	6.61833	6	7	8
195	R:R:Y482	7.2175	4	23	8
196	R:R:W488	6.16833	6	7	9
197	R:R:V502	4.255	4	4	9
198	R:R:E506	6.58	4	0	8
199	R:R:Y510	5.905	4	15	7
200	R:R:W520	6.065	4	0	7
201	R:R:M542	8.515	4	15	9
202	R:R:W546	7.7675	4	0	9
203	R:R:Y563	8.08167	6	4	9
204	R:R:V566	4.075	4	4	9
205	R:R:L570	5.702	5	4	9
206	R:R:P571	5.3775	4	4	9
207	R:R:D573	6.1875	4	4	8
208	R:R:Y582	5.51167	6	4	9
209	R:R:F594	7.82	4	0	8
210	R:R:Y601	7.98	5	0	9
211	R:R:Y605	5.062	5	26	9
212	R:R:D633	6.15	4	0	8
213	R:R:V656	4.7125	4	4	7
214	R:R:V664	5.192	5	7	9
215	R:R:Y667	5.75857	7	4	9
216	R:R:N674	8.0175	4	13	9
217	R:R:L677	4.035	4	13	9
218	R:R:Y678	5.75333	6	13	9
219	R:R:F685	5.82	6	17	9
220	R:R:R687	11.6825	4	14	7
221	R:R:D688	7.9625	4	14	9
222	R:R:I691	2.5675	4	14	6
223	W:W:?1	7.83471	17	4	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:F64	L:L:S61	21.3573	3.96	No	No	0	0	0
2	L:L:S61	L:L:W47	21.6825	4.94	No	Yes	0	0	0
3	L:L:W47	M:M:Q98	13.2235	17.52	Yes	Yes	1	0	0
4	L:L:L45	M:M:F100	11.5699	12.18	Yes	Yes	1	0	0
5	L:L:L45	M:M:Y87	22.5441	10.55	Yes	Yes	1	0	0
6	M:M:G103	M:M:Y87	24.0674	4.35	No	Yes	0	0	0
7	M:M:G103	M:M:Q6	22.3454	6.58	No	Yes	0	0	0
8	L:L:L45	L:L:V37	11.2421	5.96	Yes	Yes	1	0	0
9	M:M:P7	M:M:Q6	10.7484	4.74	Yes	Yes	3	0	0
10	M:M:Q6	M:M:T104	10.6956	11.34	Yes	Yes	3	0	0
11	M:M:P7	M:M:V11	10.9403	3.53	Yes	Yes	3	0	0
12	M:M:T104	M:M:V11	10.7501	4.76	Yes	Yes	3	0	0
13	M:M:V11	M:M:V19	21.8347	3.21	Yes	Yes	3	0	0
14	M:M:L78	M:M:V19	100	5.96	No	Yes	0	0	0
15	M:M:G13	M:M:L78	99.8772	1.71	No	No	0	0	0
16	M:M:G13	M:M:S12	99.8157	1.86	No	No	0	0	0
17	M:M:L109	M:M:S12	99.6309	4.5	No	No	0	0	0
18	M:M:P55	M:M:V58	80.5671	7.07	No	No	0	0	0
19	M:M:L47	M:M:V58	80.5238	2.98	No	No	0	0	0
20	M:M:F62	M:M:L47	80.0875	6.09	Yes	No	0	0	0
21	M:M:F62	M:M:I75	79.6201	8.79	Yes	Yes	3	0	0
22	M:M:Q53	M:M:Y49	25.2941	11.27	Yes	Yes	1	0	0
23	R:R:N208	R:R:Y185	30.209	9.3	Yes	Yes	1	5	7
24	R:R:N208	R:R:S234	55.1174	5.96	Yes	Yes	1	5	9
25	R:R:R255	R:R:S234	54.9471	3.95	Yes	Yes	0	4	9
26	R:R:Y185	R:R:Y206	30.0993	13.9	Yes	Yes	1	7	6
27	R:R:L230	R:R:Y206	36.528	8.21	No	Yes	1	4	6
28	R:R:E251	R:R:L230	36.5188	13.25	Yes	No	1	5	4
29	R:R:E251	R:R:R274	36.4819	3.49	Yes	Yes	1	5	3
30	M:M:L109	M:M:Y143	99.5692	2.34	No	Yes	0	0	0
31	M:M:P144	M:M:Y143	49.5536	9.74	No	Yes	0	0	0
32	M:M:H200	M:M:P144	49.2946	3.05	Yes	No	5	0	0
33	M:M:H200	M:M:P116	49.0929	7.63	Yes	Yes	5	0	0
34	M:M:I139	M:M:P116	88.3824	3.39	No	Yes	5	0	0
35	M:M:Y143	M:M:Y175	49.6447	3.97	Yes	Yes	0	0	0
36	M:M:F142	M:M:Y175	49.218	11.35	Yes	Yes	5	0	0
37	M:M:F142	M:M:P116	49.1072	7.22	Yes	Yes	5	0	0
38	M:M:A177	M:M:I139	88.8695	3.25	No	No	0	0	0
39	M:M:A177	M:M:T165	88.6983	1.68	No	No	0	0	0
40	M:M:S178	M:M:T165	46.1964	6.4	No	No	0	0	0
41	M:M:S178	M:M:Y180	42.2284	6.36	No	Yes	0	0	0
42	L:L:V177	M:M:T165	42.3314	3.17	No	No	0	0	0
43	L:L:V177	M:M:Y180	42.1536	5.05	No	Yes	0	0	0
44	L:L:L149	M:M:Y180	40.1684	3.52	Yes	Yes	6	0	0
45	M:M:T134	M:M:Y180	39.8014	3.75	Yes	Yes	0	0	0
46	M:M:E127	M:M:T134	35.015	9.88	Yes	Yes	0	0	0
47	L:L:L149	M:M:E127	35.1265	3.98	Yes	Yes	6	0	0
48	M:M:E127	M:M:S124	67.1998	4.31	Yes	No	6	0	0
49	L:L:P131	M:M:S124	66.4901	3.56	Yes	No	0	0	0
50	L:L:F64	L:L:M48	16.0342	6.22	No	Yes	0	0	0
51	L:L:K217	L:L:P131	36.2383	8.36	No	Yes	0	0	0
52	L:L:K217	L:L:V129	35.4998	4.55	No	Yes	0	0	0
53	L:L:V129	L:L:V206	32.5837	6.41	Yes	No	0	0	0
54	L:L:V150	L:L:V206	29.6258	4.81	No	No	0	0	0
55	L:L:V150	L:L:Y153	27.4049	6.31	No	Yes	9	0	0
56	L:L:P127	L:L:Y153	10.3719	5.56	Yes	Yes	9	0	0
57	L:L:P131	L:L:V219	27.3716	5.3	Yes	No	0	0	0
58	L:L:L146	L:L:V219	26.6325	7.45	Yes	No	0	0	0
59	L:L:L146	L:L:P134	12.61	6.57	Yes	Yes	0	0	0
60	L:L:L197	L:L:P134	10.3855	3.28	Yes	Yes	0	0	0
61	R:R:R274	R:R:T399	36.4832	5.17	Yes	No	0	3	4
62	R:R:P400	R:R:T399	91.0458	3.5	Yes	No	0	9	4
63	R:R:C398	R:R:P400	90.7188	3.77	No	Yes	24	9	9
64	R:R:C398	R:R:L277	90.636	3.17	No	Yes	0	9	9
65	R:R:L252	R:R:L277	44.0849	2.77	Yes	Yes	0	9	9
66	R:R:L231	R:R:L252	41.0715	2.77	Yes	Yes	12	7	9
67	R:R:L231	R:R:V205	39.9335	2.98	Yes	Yes	0	7	7
68	R:R:L182	R:R:V205	23.9239	4.47	No	Yes	0	6	7
69	R:R:L180	R:R:L182	10.846	6.92	No	No	0	7	6
70	R:R:F154	R:R:L180	10.7138	4.87	Yes	No	0	6	7
71	R:R:D276	R:R:R255	54.7359	21.44	No	Yes	0	4	4
72	R:R:D276	R:R:T399	54.6655	15.9	No	No	0	4	4
73	R:R:L207	R:R:V205	15.3703	2.98	No	Yes	0	7	7
74	R:R:L184	R:R:L207	12.1672	5.54	Yes	No	0	8	7
75	R:R:F172	R:R:L182	12.9713	8.53	Yes	No	0	8	6
76	R:R:F141	R:R:F172	10.3706	9.65	Yes	Yes	0	7	8
77	R:R:I117	R:R:P142	13.8002	3.39	No	Yes	2	8	9
78	R:R:I117	R:R:L92	13.5576	4.28	No	Yes	2	8	8
79	R:R:I67	R:R:P68	12.5657	3.39	Yes	No	0	5	5
80	R:R:E93	R:R:P68	12.1836	4.72	No	No	0	6	5
81	R:R:H282	R:R:L277	52.4218	5.14	No	Yes	0	9	9
82	R:R:H282	R:R:Y279	52.0432	7.62	No	Yes	0	9	9
83	R:R:I486	R:R:Y279	51.4364	12.09	No	Yes	0	8	9
84	R:R:I486	R:R:S281	50.95	3.1	No	No	0	8	9
85	R:R:A485	R:R:S281	50.8283	3.42	No	No	0	9	9
86	R:R:A485	R:R:Y481	50.7065	5.34	No	Yes	0	9	8
87	R:R:Q489	R:R:Y481	43.3299	9.02	No	Yes	0	9	8
88	R:R:N406	R:R:Q489	43.2052	7.92	No	No	0	9	9
89	R:R:D403	R:R:N406	43.0807	6.73	No	No	0	8	9
90	R:R:D403	R:R:F405	42.9565	9.55	No	Yes	0	8	8
91	R:R:F405	W:W:?1	40.4147	6.11	Yes	Yes	4	8	0
92	R:R:Y667	W:W:?1	22.0423	9.25	Yes	Yes	4	9	0
93	R:R:M463	R:R:Y667	21.3052	7.18	No	Yes	0	9	9
94	R:R:M463	R:R:S671	21.1749	6.13	No	No	0	9	9
95	R:R:D460	R:R:S671	20.7839	4.42	Yes	No	0	9	9
96	R:R:D460	R:R:N674	15.1753	8.08	Yes	Yes	13	9	9
97	R:R:N674	R:R:Y678	11.1301	3.49	Yes	Yes	13	9	9
98	R:R:S505	W:W:?1	12.4242	3.23	No	Yes	4	9	0
99	R:R:E506	R:R:S505	12.3661	5.75	Yes	No	0	8	9
100	R:R:C549	R:R:E506	11.7165	3.04	No	Yes	0	8	8
101	R:R:C549	R:R:L507	11.5853	3.17	No	No	0	8	9
102	R:R:L507	R:R:W546	11.3261	11.39	No	Yes	0	9	9
103	R:R:N455	R:R:W546	10.6782	5.65	No	Yes	0	8	9
104	M:M:I75	M:M:V19	79.1101	3.07	Yes	Yes	3	0	0
105	M:M:P55	M:M:Y49	76.8602	8.34	No	Yes	1	0	0
106	M:M:Y49	R:R:Y185	50.2018	8.94	Yes	Yes	1	0	7
107	M:M:Q53	R:R:N208	25.1949	5.28	Yes	Yes	1	0	5

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
M:M:N30	R:R:N110	4.09	1	No	No	0	6	0	1
M:M:N31	R:R:R109	9.64	1	Yes	Yes	0	5	0	1
M:M:Y49	R:R:Y185	8.94	1	Yes	Yes	0	7	0	1
M:M:Y50	R:R:F134	3.09	1	Yes	Yes	0	5	0	1
M:M:Y50	R:R:E157	5.61	1	Yes	Yes	0	8	0	1
M:M:D51	R:R:K209	4.15	0	No	Yes	0	7	0	1
M:M:Q53	R:R:N208	5.28	1	Yes	Yes	0	5	0	1
M:M:Q53	R:R:K209	10.85	1	Yes	Yes	0	7	0	1
M:M:Q53	R:R:Q235	5.12	1	Yes	No	0	4	0	1
M:M:L54	R:R:R255	12.15	0	No	Yes	0	4	0	1
M:M:S56	R:R:E251	4.31	1	No	Yes	0	5	0	1
M:M:S56	R:R:I253	3.1	1	No	Yes	0	4	0	1
M:M:S56	R:R:R274	3.95	1	No	Yes	0	3	0	1
M:M:D93	R:R:I85	7	1	No	No	0	6	0	1
L:L:R28	R:R:K129	9.9	1	Yes	Yes	0	5	0	1
L:L:R28	R:R:D151	5.96	1	Yes	No	0	4	0	1
L:L:R28	R:R:F153	7.48	1	Yes	Yes	0	5	0	1
L:L:S31	R:R:K129	4.59	1	No	Yes	0	5	0	1
L:L:Y32	R:R:I155	3.63	1	Yes	Yes	0	5	0	1
L:L:D52	R:R:R80	9.53	1	Yes	Yes	0	4	0	1
L:L:D52	R:R:H105	6.3	1	Yes	Yes	0	7	0	1
L:L:T54	R:R:K129	9.01	1	Yes	Yes	0	5	0	1
L:L:D55	R:R:R80	13.1	1	Yes	Yes	0	4	0	1
L:L:Y57	R:R:D36	5.75	1	Yes	No	0	3	0	1
L:L:Y57	R:R:R38	21.61	1	Yes	No	0	4	0	1
L:L:Y57	R:R:T56	7.49	1	Yes	No	0	5	0	1
L:L:Y57	R:R:K58	3.58	1	Yes	Yes	0	5	0	1
L:L:Y57	R:R:R80	13.38	1	Yes	Yes	0	4	0	1
L:L:T58	R:R:E35	8.47	19	No	No	0	1	0	1
L:L:Y60	R:R:E35	3.37	19	Yes	No	0	1	0	1
L:L:K65	R:R:E34	12.15	0	No	No	0	4	0	1
L:L:E100	R:R:K183	4.05	1	Yes	Yes	0	6	0	1
L:L:P101	R:R:F130	8.67	1	No	Yes	0	6	0	1
L:L:P101	R:R:I155	5.08	1	No	Yes	0	5	0	1
L:L:G102	R:R:E107	4.91	1	No	Yes	0	6	0	1
L:L:G102	R:R:F130	3.01	1	No	Yes	0	6	0	1
L:L:Y103	R:R:K58	9.55	1	Yes	Yes	0	5	0	1
L:L:Y103	R:R:Y82	14.89	1	Yes	Yes	0	4	0	1
L:L:Y103	R:R:E107	3.37	1	Yes	Yes	0	6	0	1
L:L:S104	R:R:R109	13.18	1	No	Yes	0	5	0	1
L:L:W107	R:R:Y185	5.79	1	Yes	Yes	0	7	0	1
R:R:D36	R:R:R38	15.48	1	No	No	3	4	1	1
R:R:D36	R:R:Q55	3.92	1	No	No	3	4	1	2
R:R:K58	R:R:T40	7.51	1	Yes	Yes	5	8	1	2
R:R:R80	R:R:T56	9.06	1	Yes	No	4	5	1	1
R:R:K58	R:R:Y82	5.97	1	Yes	Yes	5	4	1	1
R:R:R80	R:R:Y82	15.43	1	Yes	Yes	4	4	1	1
R:R:H105	R:R:R80	15.8	1	Yes	Yes	7	4	1	1
R:R:H105	R:R:Y82	5.44	1	Yes	Yes	7	4	1	1
R:R:E107	R:R:Y82	7.86	1	Yes	Yes	6	4	1	1
R:R:I85	R:R:S84	7.74	0	No	No	6	7	1	2
R:R:H105	R:R:T104	8.21	1	Yes	No	7	5	1	2
R:R:H105	R:R:K129	5.24	1	Yes	Yes	7	5	1	1
R:R:F130	R:R:H105	5.66	1	Yes	Yes	6	7	1	1
R:R:E107	R:R:R109	8.14	1	Yes	Yes	6	5	1	1
R:R:E107	R:R:F130	5.83	1	Yes	Yes	6	6	1	1
R:R:E107	R:R:F134	8.16	1	Yes	Yes	6	5	1	1
R:R:N110	R:R:R109	10.85	0	No	Yes	6	5	1	1
R:R:F134	R:R:R109	11.76	1	Yes	Yes	5	5	1	1
R:R:N110	R:R:N135	8.17	0	No	No	6	8	1	2
R:R:D151	R:R:K129	13.83	1	No	Yes	4	5	1	1
R:R:F130	R:R:G132	3.01	1	Yes	No	6	5	1	2
R:R:F130	R:R:I155	3.77	1	Yes	Yes	6	5	1	1
R:R:E157	R:R:F130	4.66	1	Yes	Yes	8	6	1	1
R:R:F134	R:R:G132	4.52	1	Yes	No	5	5	1	2
R:R:E157	R:R:F134	16.32	1	Yes	Yes	8	5	1	1
R:R:F134	R:R:T159	6.49	1	Yes	Yes	5	5	1	2
R:R:F153	R:R:I155	5.02	0	Yes	Yes	5	5	1	1
R:R:F153	R:R:T179	3.89	0	Yes	No	5	5	1	2
R:R:F153	R:R:T181	7.78	0	Yes	No	5	7	1	2
R:R:E157	R:R:T159	8.47	1	Yes	Yes	8	5	1	2
R:R:E157	R:R:K183	13.5	1	Yes	Yes	8	6	1	1
R:R:T159	R:R:Y185	6.24	1	Yes	Yes	5	7	2	1
R:R:K183	R:R:Y185	4.78	1	Yes	Yes	6	7	1	1
R:R:K183	R:R:Y206	3.58	1	Yes	Yes	6	6	1	2
R:R:Y185	R:R:Y206	13.9	1	Yes	Yes	7	6	1	2
R:R:N208	R:R:Y185	9.3	1	Yes	Yes	5	7	1	1
R:R:K209	R:R:N186	19.58	1	Yes	No	7	7	1	2
R:R:L230	R:R:Y206	8.21	1	No	Yes	4	6	2	2
R:R:D232	R:R:Y206	6.9	1	Yes	Yes	9	6	2	2
R:R:D232	R:R:N208	16.16	1	Yes	Yes	9	5	2	1
R:R:N208	R:R:S234	5.96	1	Yes	Yes	5	9	1	2
R:R:K209	R:R:Q235	4.07	1	Yes	No	7	4	1	1
R:R:E251	R:R:L230	13.25	1	Yes	No	5	4	1	2
R:R:D232	R:R:S234	7.36	1	Yes	Yes	9	9	2	2
R:R:D232	R:R:I253	15.39	1	Yes	Yes	9	4	2	1
R:R:I253	R:R:S234	3.1	1	Yes	Yes	4	9	1	2
R:R:R255	R:R:S234	3.95	0	Yes	Yes	4	9	1	2
R:R:E251	R:R:I253	8.2	1	Yes	Yes	5	4	1	1
R:R:E251	R:R:R274	3.49	1	Yes	Yes	5	3	1	1
R:R:D276	R:R:R255	21.44	0	No	Yes	4	4	2	1
R:R:R274	R:R:T399	5.17	1	Yes	No	3	4	1	2
R:R:D276	R:R:T399	15.9	0	No	No	4	4	2	2
R:R:E61	R:R:I85	2.73	0	No	No	5	6	2	1
R:R:R274	R:R:T273	2.59	1	Yes	No	3	4	1	2
M:M:G57	R:R:R255	1.5	0	No	Yes	0	4	0	1
R:R:D151	R:R:I152	1.4	1	No	No	4	3	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:D403	R:R:F405	9.55	0	No	Yes	8	8	2	1
R:R:F405	R:R:K565	4.96	4	Yes	No	8	7	1	2
R:R:F405	R:R:V566	3.93	4	Yes	Yes	8	9	1	2
R:R:F405	R:R:M572	3.73	4	Yes	No	8	9	1	1
R:R:F405	W:W:?1	6.11	4	Yes	Yes	8	0	1	0
R:R:P407	R:R:V656	7.07	4	No	Yes	9	7	2	1
R:R:M463	R:R:Y667	7.18	0	No	Yes	9	9	2	1
R:R:L570	R:R:T501	4.42	4	Yes	No	9	9	1	2
R:R:T501	R:R:Y667	4.99	4	No	Yes	9	9	2	1
R:R:V502	R:R:Y563	6.31	4	Yes	Yes	9	9	2	2
R:R:P571	R:R:V502	3.53	4	Yes	Yes	9	9	1	2
R:R:E506	R:R:S505	5.75	0	Yes	No	8	9	2	1
R:R:S505	R:R:Y667	6.36	4	No	Yes	9	9	1	1
R:R:S505	W:W:?1	3.23	4	No	Yes	9	0	1	0
R:R:P571	R:R:Y563	8.34	4	Yes	Yes	9	9	1	2
R:R:I568	R:R:V566	3.07	0	No	Yes	9	9	2	2
R:R:M572	R:R:V566	6.09	4	No	Yes	9	9	1	2
R:R:V566	R:R:V656	3.21	4	Yes	Yes	9	7	2	1
R:R:I568	R:R:L570	5.71	0	No	Yes	9	9	2	1
R:R:L570	R:R:P571	4.93	4	Yes	Yes	9	9	1	1
R:R:L570	R:R:Y667	3.52	4	Yes	Yes	9	9	1	1
R:R:L570	W:W:?1	9.93	4	Yes	Yes	9	0	1	0
R:R:P571	W:W:?1	4.71	4	Yes	Yes	9	0	1	0
R:R:M572	W:W:?1	15.21	4	No	Yes	9	0	1	0
R:R:T574	W:W:?1	12.68	0	No	Yes	6	0	1	0
R:R:A644	R:R:L587	3.15	4	No	No	9	8	1	1
R:R:L587	R:R:L645	5.54	4	No	No	8	7	1	2
R:R:L587	W:W:?1	2.98	4	No	Yes	8	0	1	0
R:R:I640	R:R:P639	3.39	4	No	No	9	9	1	2
R:R:I640	R:R:Y667	4.84	4	No	Yes	9	9	1	1
R:R:I640	W:W:?1	14.33	4	No	Yes	9	0	1	0
R:R:I654	R:R:Y643	12.09	0	No	No	9	8	1	2
R:R:L662	R:R:Y643	5.86	0	No	No	8	8	1	2
R:R:A644	W:W:?1	6.78	4	No	Yes	9	0	1	0
R:R:A647	R:R:P652	3.74	4	No	No	9	9	1	1
R:R:A647	W:W:?1	6.78	4	No	Yes	9	0	1	0
R:R:P652	W:W:?1	5.89	4	No	Yes	9	0	1	0
R:R:I654	R:R:N658	4.25	0	No	No	9	8	1	2
R:R:I654	W:W:?1	10.23	0	No	Yes	9	0	1	0
R:R:S659	R:R:V656	3.23	4	No	Yes	9	7	1	1
R:R:V656	W:W:?1	5.34	4	Yes	Yes	7	0	1	0
R:R:S659	W:W:?1	11.84	4	No	Yes	9	0	1	0
R:R:F666	R:R:L662	3.65	0	No	No	8	8	2	1
R:R:L662	W:W:?1	6.95	0	No	Yes	8	0	1	0
R:R:P668	R:R:Y667	4.17	0	No	Yes	9	9	2	1
R:R:Y667	W:W:?1	9.25	4	Yes	Yes	9	0	1	0
R:R:L580	R:R:T574	2.95	0	No	No	4	6	2	1
R:R:E404	W:W:?1	0.95	0	No	Yes	7	0	1	0

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	7T9N_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	2.98
Number of Linked Nodes	950
Number of Links	1235
Number of Hubs	223
Number of Links mediated by Hubs	784
Number of Communities	26
Number of Nodes involved in Communities	337
Number of Links involved in Communities	524

Path Summary
Number Of Nodes in MetaPath	108
Number Of Links MetaPath	107
Number of Shortest Paths	5142754
Length Of Smallest Path	3
Average Path Length	40.5195
Length of Longest Path	74
Minimum Path Strength	1.355
Average Path Strength	5.98664
Maximum Path Strength	23.55
Minimum Path Correlation	0.71
Average Path Correlation	0.995382
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	2.94118
Average % Of Corr. Nodes	36.0509
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	52.1452
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain • L domain-like
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain • L domain-like
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	Z41
PDB Residues	W:W:?1
Environment Details	Open EMBL-EBI Page
Code	Z41
Name	(2S)-3-hydroxypropane-1,2-diyl dihexadecanoate
Synonyms
Identifier
Formula	C35 H68 O5
Molecular Weight	568.911
SMILES
PubChem	644078
Formal Charge	0
Total Atoms	108
Total Chiral Atoms	1
Total Bonds	107
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P16473
Sequence	>7T9N_nogp_Chain_R P C E C H Q E E D F R V T C K D I Q R I P S L P P S T Q T L K L I E T H L R T I P S H A F S N L P N I S R I Y V S I D V T L Q Q L E S H S F Y N L S K V T H I E I R N T R N L T Y I D P D A L K E L P L L K F L G I F N T G L K M F P D L T K V Y S T D I F F I L E I T D N P Y M T S I P V N A F Q G L C N E T L T L K L Y N N G F T S V Q G Y A F N G T K L D A V Y L N K N K Y L T V I D K D A F G G V Y S G P S L L D V S Q T S V T A L P S K G L E H L K E L I A R N T W T L K K L P L S L S F L H L T R A D L S Y P S H C C A F K M V C T P K S D E F N P C E D I M G Y K F L R I V V W F V S L L A L L G N V F V L L I L L T S H Y K L N V P R F L M C N L A F A D F C M G M Y L L L I A S V D L Y T H S E Y Y N H A I D W Q T G P G C N T A G F F T V F A S E L S V Y T L T V I T L E R W Y A I T F A M R L D R K I R L R H A C A I M V G G W V C C F L L A L L P L V G I S S Y A K V S I C L P M D T E T P L A L A Y I V F V L T L N I V A F V I V C C C Y V K I Y I T V R N D T K I A K R M A V L I F T D F I C M A P I S F Y A L S A I L N K P L I T V S N S K I L L V L F Y P L N S C A N P F L Y A I F T K A F Q R D V F I L L S K F G I Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	7XW5	A	Protein	Glycoprotein Hormone	TSH	Homo sapiens	TSH	ML109	Gs/β1/γ2	2.96	2022-08-24	10.1038/s41586-022-05173-3
	7XW5 (No Gprot)	A	Protein	Glycoprotein Hormone	TSH	Homo sapiens	TSH	ML109		2.96	2022-08-24	10.1038/s41586-022-05173-3
	7XW7	A	Protein	Glycoprotein Hormone	TSH	Homo sapiens	K1-70	-	-	5.5	2022-08-17	10.1038/s41586-022-05173-3
	7XW6	A	Protein	Glycoprotein Hormone	TSH	Homo sapiens	M22 Fab	ML109	Gs/β1/γ2	2.78	2022-08-17	10.1038/s41586-022-05173-3
	7XW6 (No Gprot)	A	Protein	Glycoprotein Hormone	TSH	Homo sapiens	M22 Fab	ML109		2.78	2022-08-17	10.1038/s41586-022-05173-3
	7T9M	A	Protein	Glycoprotein Hormone	TSH	Homo sapiens	-	CS-17 Antibody	-	3.1	2022-08-10	10.1038/s41586-022-05159-1
	7UTZ	A	Protein	Glycoprotein Hormone	TSH	Homo sapiens	TR1402	PubChem 644078	Gs/β1/γ2	2.4	2022-08-03	10.1038/s41586-022-05159-1
	7UTZ (No Gprot)	A	Protein	Glycoprotein Hormone	TSH	Homo sapiens	TR1402	PubChem 644078		2.4	2022-08-03	10.1038/s41586-022-05159-1
	7T9N	A	Protein	Glycoprotein Hormone	TSH	Homo sapiens	M22 Fab	PubChem 644078	Gs/β1/γ2	2.9	2022-08-03	10.1038/s41586-022-05159-1
	7T9N (No Gprot)	A	Protein	Glycoprotein Hormone	TSH	Homo sapiens	M22 Fab	PubChem 644078		2.9	2022-08-03	10.1038/s41586-022-05159-1
	7T9I	A	Protein	Glycoprotein Hormone	TSH	Homo sapiens	TSH	-	Gs/β1/γ2	2.9	2022-08-03	10.1038/s41586-022-05159-1
	7T9I (No Gprot)	A	Protein	Glycoprotein Hormone	TSH	Homo sapiens	TSH	-		2.9	2022-08-03	10.1038/s41586-022-05159-1

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