psnGPCR

Press and hold down the left mouse button and move the mouse to rotate.
Press and hold down the central mouse button and move the mouse to translate.
Use the mouse wheel to zoom in or out.
Click on any atom on your molecule and the corresponding residue label will be placed beneath the viewer.

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	E:E:C82	E:E:M33	8.1	No	Yes	0	9	8
2	E:E:L88	E:E:M33	4.24	No	Yes	0	6	8
3	E:E:L34	E:E:L88	12.46	No	No	0	5	6
4	E:E:L39	E:E:R36	15.79	No	No	0	1	3
5	E:E:E76	E:E:L37	6.63	Yes	No	0	6	8
6	E:E:F92	E:E:P38	2.89	Yes	No	0	8	5
7	E:E:E76	E:E:L39	3.98	Yes	No	0	6	1
8	E:E:C40	E:E:C72	5.46	Yes	No	1	9	9
9	E:E:C40	E:E:T73	3.38	Yes	No	1	9	9
10	E:E:C40	E:E:E76	4.56	Yes	Yes	1	9	6
11	E:E:F92	E:E:G41	3.01	Yes	No	0	8	7
12	E:E:F44	E:E:M48	16.17	Yes	Yes	1	9	9
13	E:E:F44	E:E:Y66	4.13	Yes	No	0	9	9
14	E:E:F44	E:E:F69	16.08	Yes	Yes	1	9	8
15	E:E:F44	E:E:I96	3.77	Yes	No	1	9	6
16	E:E:F100	E:E:F44	10.72	Yes	Yes	1	8	9
17	E:E:F101	E:E:F44	3.22	Yes	Yes	1	9	9
18	E:E:K50	E:E:M47	17.28	No	No	0	3	4
19	E:E:M47	E:E:Y65	28.74	No	No	0	4	5
20	E:E:M48	E:E:W56	3.49	Yes	Yes	1	9	7
21	E:E:F100	E:E:M48	16.17	Yes	Yes	1	8	9
22	E:E:K55	E:E:V51	4.55	Yes	No	1	4	6
23	E:E:E61	E:E:V51	5.7	Yes	No	1	6	6
24	E:E:D52	E:E:W54	4.47	No	No	0	6	3
25	E:E:D52	E:E:K55	17.97	No	Yes	0	6	4
26	E:E:K55	E:E:N58	9.79	Yes	No	1	4	8
27	E:E:E61	E:E:K55	13.5	Yes	Yes	1	6	4
28	E:E:F100	E:E:W56	11.02	Yes	Yes	1	8	7
29	E:E:C104	E:E:C57	7.28	No	No	0	9	9
30	E:E:C57	E:E:V106	3.42	No	No	0	9	4
31	E:E:N58	E:E:S60	10.43	No	No	1	8	7
32	E:E:E61	E:E:N58	7.89	Yes	No	1	6	8
33	E:E:F62	E:E:L59	8.53	No	Yes	1	8	7
34	E:E:L59	E:E:V106	11.92	Yes	No	1	7	4
35	E:E:L59	E:E:R108	4.86	Yes	No	1	7	4
36	E:E:L59	R:R:Y53	4.69	Yes	Yes	1	7	1
37	E:E:E61	E:E:S60	4.31	Yes	No	1	6	7
38	E:E:F101	E:E:F62	4.29	Yes	No	1	9	8
39	E:E:F62	R:R:Y53	8.25	No	Yes	1	8	1
40	E:E:V64	E:E:Y65	5.05	No	No	0	4	5
41	E:E:H97	E:E:Y66	4.36	Yes	No	0	9	9
42	E:E:Y66	R:R:Q52	3.38	No	Yes	0	9	6
43	E:E:E67	R:R:R45	16.28	No	No	0	4	7
44	E:E:E67	H:H:?1	11.89	No	No	0	4	0
45	E:E:F69	E:E:T73	3.89	Yes	No	1	8	9
46	E:E:F69	E:E:F92	6.43	Yes	Yes	1	8	8
47	E:E:F69	E:E:I93	5.02	Yes	No	1	8	9
48	E:E:F69	E:E:I96	7.54	Yes	No	1	8	6
49	E:E:T70	E:E:W84	4.85	No	Yes	1	9	9
50	E:E:T70	R:R:Q52	8.5	No	Yes	1	9	6
51	E:E:N71	H:H:?1	29.57	No	No	0	4	0
52	E:E:C72	E:E:E76	4.56	No	Yes	1	9	6
53	E:E:I93	E:E:T73	4.56	No	No	1	9	9
54	E:E:E74	E:E:W84	29.44	No	Yes	1	5	9
55	E:E:E74	L:L:Y37	5.61	No	Yes	1	5	0
56	E:E:C82	E:E:N86	6.3	No	No	0	9	9
57	E:E:Y83	R:R:N124	6.98	No	No	3	6	5
58	E:E:Y83	R:R:R126	23.66	No	No	3	6	4
59	E:E:P85	E:E:W84	12.16	No	Yes	0	9	9
60	E:E:W84	L:L:Y37	6.75	Yes	Yes	1	9	0
61	E:E:W84	R:R:Q52	3.29	Yes	Yes	1	9	6
62	E:E:W84	R:R:W76	4.69	Yes	Yes	1	9	8
63	E:E:P85	R:R:R126	2.88	No	No	0	9	4
64	E:E:A89	E:E:N86	4.69	No	No	0	8	9
65	E:E:P87	H:H:?3	4.42	No	No	0	5	0
66	E:E:Q90	R:R:Y56	10.15	No	Yes	0	9	3
67	E:E:Q90	R:R:T75	8.5	No	No	0	9	5
68	E:E:G91	E:E:T94	3.64	No	No	0	4	7
69	E:E:F92	E:E:I96	3.77	Yes	No	1	8	6
70	E:E:I93	R:R:Y56	14.51	No	Yes	1	9	3
71	E:E:F101	E:E:H97	14.71	Yes	Yes	1	9	9
72	E:E:H97	R:R:Y53	8.71	Yes	Yes	1	9	1
73	E:E:H97	R:R:Y56	5.44	Yes	Yes	1	9	3
74	E:E:R98	E:E:S102	5.27	No	No	0	6	7
75	E:E:R98	R:R:Q60	22.2	No	No	0	6	3
76	E:E:F100	E:E:F101	5.36	Yes	Yes	1	8	9
77	E:E:F101	R:R:Y53	14.44	Yes	Yes	1	9	1
78	E:E:C104	E:E:N103	3.15	No	No	0	9	8
79	E:E:V106	R:R:Y53	5.05	No	Yes	1	4	1
80	E:E:D107	E:E:V109	4.38	No	No	0	5	5
81	E:E:D107	R:R:K54	5.53	No	No	0	5	4
82	E:E:R108	R:R:K46	3.71	No	No	1	4	4
83	E:E:R108	R:R:D50	5.96	No	No	1	4	2
84	E:E:E112	E:E:V109	14.26	No	No	0	4	5
85	E:E:L111	R:R:F285	14.61	No	Yes	0	4	6
86	E:E:D113	E:E:P114	4.83	No	Yes	0	9	9
87	E:E:D113	R:R:T295	8.67	No	Yes	0	9	4
88	E:E:D113	R:R:H296	3.78	No	No	0	9	2
89	E:E:P114	E:E:V118	3.53	Yes	No	0	9	7
90	E:E:P114	R:R:Y284	22.25	Yes	No	0	9	2
91	E:E:P114	R:R:L297	4.93	Yes	Yes	0	9	4
92	E:E:E117	E:E:P115	7.86	No	No	0	4	8
93	E:E:P115	E:E:V118	3.53	No	No	0	8	7
94	E:E:D116	E:E:I120	5.6	No	No	0	6	5
95	E:E:I123	E:E:L119	4.28	No	No	0	9	9
96	E:E:L119	R:R:H296	6.43	No	No	0	9	2
97	E:E:I120	E:E:P121	3.39	No	No	0	5	5
98	E:E:L122	R:R:T280	2.95	No	No	2	9	4
99	E:E:L122	R:R:I300	4.28	No	Yes	2	9	8
100	E:E:I123	R:R:Y299	3.63	No	Yes	0	9	7
101	E:E:I125	E:E:P126	3.39	No	No	0	5	9
102	E:E:I125	E:E:L129	2.85	No	No	0	5	7
103	E:E:V127	R:R:P304	5.3	No	No	0	7	9
104	E:E:T130	R:R:F235	7.78	No	Yes	6	9	5
105	E:E:T130	R:R:F269	5.19	No	Yes	6	9	3
106	E:E:T130	R:R:P304	5.25	No	No	0	9	9
107	E:E:M133	R:R:L265	4.24	No	Yes	0	9	7
108	E:E:M133	R:R:F269	6.22	No	Yes	0	9	3
109	E:E:G135	E:E:V138	3.68	No	No	0	7	9
110	E:E:L136	R:R:W261	6.83	No	Yes	0	6	2
111	E:E:V137	R:R:I242	6.14	Yes	Yes	4	9	7
112	E:E:V137	R:R:Y262	8.83	Yes	Yes	4	9	7
113	E:E:V137	R:R:L265	2.98	Yes	Yes	0	9	7
114	E:E:V138	R:R:I242	3.07	No	Yes	0	9	7
115	E:E:R140	E:E:W139	10	No	No	0	8	9
116	E:E:R140	R:R:W261	10	No	Yes	0	8	2
117	E:E:K142	E:E:S141	6.12	No	No	0	8	9
118	E:E:S141	R:R:Q257	7.22	No	Yes	4	9	5
119	E:E:S141	R:R:Y262	3.82	No	Yes	4	9	7
120	E:E:K142	R:R:A251	3.21	No	No	0	8	6
121	E:E:K142	R:R:T254	3	No	No	0	8	6
122	E:E:R143	R:R:R258	5.33	No	No	0	8	5
123	L:L:K1	L:L:R11	3.71	No	No	2	0	0
124	L:L:K1	R:R:V293	4.55	No	Yes	2	0	6
125	L:L:K1	R:R:E294	8.1	No	No	0	0	3
126	L:L:C2	L:L:T4	3.38	Yes	Yes	2	0	0
127	L:L:C2	L:L:C7	7.28	Yes	Yes	2	0	0
128	L:L:C2	R:R:L298	3.17	Yes	Yes	2	0	6
129	L:L:C2	R:R:Y299	8.06	Yes	Yes	2	0	7
130	L:L:C2	R:R:H302	4.42	Yes	Yes	2	0	6
131	L:L:N3	R:R:W361	21.47	No	No	0	0	4
132	L:L:N3	R:R:R362	6.03	No	Yes	0	0	4
133	L:L:T4	L:L:T6	4.71	Yes	Yes	2	0	0
134	L:L:C7	L:L:T4	3.38	Yes	Yes	2	0	0
135	L:L:T4	R:R:Y299	3.75	Yes	Yes	2	0	7
136	L:L:T6	R:R:Y234	8.74	Yes	Yes	2	0	7
137	L:L:T6	R:R:H302	8.21	Yes	Yes	2	0	6
138	L:L:T6	R:R:V305	3.17	Yes	No	2	0	7
139	L:L:T6	R:R:M306	4.52	Yes	No	0	0	4
140	L:L:T6	R:R:F356	5.19	Yes	Yes	2	0	7
141	L:L:C7	L:L:R11	4.18	Yes	No	2	0	0
142	L:L:C7	R:R:H302	10.32	Yes	Yes	2	0	6
143	L:L:A8	R:R:H377	4.39	No	Yes	0	0	7
144	L:L:Q10	L:L:T9	4.25	Yes	No	0	0	0
145	L:L:T9	R:R:H381	6.85	No	Yes	0	0	9
146	L:L:Q10	R:R:H226	6.18	Yes	No	0	0	6
147	L:L:Q10	R:R:M230	4.08	Yes	No	2	0	6
148	L:L:Q10	R:R:H302	3.71	Yes	Yes	2	0	6
149	L:L:R11	R:R:V293	3.92	No	Yes	2	0	6
150	L:L:L12	L:L:L16	4.15	No	Yes	0	0	0
151	L:L:L12	R:R:L148	4.15	No	Yes	5	0	5
152	L:L:L12	R:R:H377	5.14	No	Yes	5	0	7
153	L:L:A13	R:R:H201	2.93	No	No	0	0	6
154	L:L:N14	L:L:R18	6.03	No	No	0	0	0
155	L:L:N14	R:R:V293	8.87	No	Yes	0	0	6
156	L:L:F15	L:L:S19	11.89	Yes	No	0	0	0
157	L:L:F15	R:R:K141	18.61	Yes	No	0	0	3
158	L:L:F15	R:R:L142	4.87	Yes	No	0	0	2
159	L:L:L16	L:L:S20	4.5	Yes	Yes	0	0	0
160	L:L:L16	R:R:Y149	4.69	Yes	Yes	0	0	5
161	L:L:L16	R:R:V206	4.47	Yes	No	0	0	3
162	L:L:V17	R:R:V206	4.81	No	No	0	0	3
163	L:L:V17	R:R:L291	4.47	No	Yes	0	0	6
164	L:L:R18	L:L:S19	6.59	No	No	0	0	0
165	L:L:R18	R:R:P104	8.65	No	No	0	0	3
166	L:L:L23	L:L:S20	3	No	Yes	7	0	0
167	L:L:S20	R:R:L142	3	Yes	No	7	0	2
168	L:L:S20	R:R:Y146	6.36	Yes	No	7	0	2
169	L:L:G24	L:L:N21	5.09	No	No	9	0	0
170	L:L:N21	L:L:P25	4.89	No	No	9	0	0
171	L:L:L27	L:L:N21	8.24	No	No	0	0	0
172	L:L:N22	R:R:G209	5.09	No	No	0	0	3
173	L:L:L23	R:R:Y146	7.03	No	No	7	0	2
174	L:L:L23	R:R:Y149	8.21	No	Yes	0	0	5
175	L:L:G24	L:L:P25	4.06	No	No	9	0	0
176	L:L:L27	L:L:P28	3.28	No	No	0	0	0
177	L:L:T30	R:R:F99	18.16	No	Yes	1	0	5
178	L:L:T30	R:R:D101	8.67	No	Yes	1	0	4
179	L:L:T30	R:R:F102	6.49	No	Yes	1	0	4
180	L:L:N31	L:L:N35	8.17	No	No	10	0	0
181	L:L:N31	L:L:T36	5.85	No	Yes	10	0	0
182	L:L:V32	R:R:N135	7.39	No	Yes	0	0	3
183	L:L:S34	R:R:H121	8.37	No	Yes	3	0	4
184	L:L:S34	R:R:E123	4.31	No	No	3	0	4
185	L:L:S34	R:R:N124	8.94	No	No	3	0	5
186	L:L:N35	L:L:T36	2.92	No	Yes	10	0	0
187	L:L:?38	L:L:T36	7.3	Yes	Yes	0	0	0
188	L:L:?38	L:L:Y37	2.9	Yes	Yes	0	0	0
189	L:L:Y37	R:R:G78	4.35	Yes	No	0	0	5
190	L:L:Y37	R:R:W79	12.54	Yes	Yes	1	0	6
191	L:L:?38	R:R:W128	11.28	Yes	Yes	0	0	5
192	L:L:?38	R:R:Y131	5.8	Yes	Yes	0	0	5
193	R:R:M48	R:R:R45	3.72	No	No	0	6	7
194	R:R:M49	R:R:R45	3.72	No	No	0	4	7
195	R:R:D50	R:R:K46	5.53	No	No	1	2	4
196	R:R:D97	R:R:K47	13.83	No	No	0	2	4
197	R:R:M48	R:R:W79	5.82	No	Yes	1	6	6
198	R:R:M48	R:R:Y98	13.17	No	Yes	1	6	4
199	R:R:M49	R:R:Q52	5.44	No	Yes	0	4	6
200	R:R:D50	R:R:K54	5.53	No	No	0	2	4
201	R:R:Q52	R:R:Y56	6.76	Yes	Yes	1	6	3
202	R:R:Q52	R:R:W76	20.81	Yes	Yes	1	6	8
203	R:R:C55	R:R:M59	3.24	No	No	1	9	5
204	R:R:C55	R:R:W76	10.45	No	Yes	1	9	8
205	R:R:C55	R:R:C81	7.28	No	No	1	9	9
206	R:R:W76	R:R:Y56	8.68	Yes	Yes	1	8	3
207	R:R:D57	R:R:Q60	7.83	No	No	0	4	3
208	R:R:L62	R:R:R58	7.29	Yes	No	1	3	3
209	R:R:R58	R:R:R74	5.33	No	Yes	1	3	4
210	R:R:M59	R:R:R74	17.37	No	Yes	1	5	4
211	R:R:C81	R:R:M59	3.24	No	No	1	9	5
212	R:R:L62	R:R:Q61	13.31	Yes	No	0	3	3
213	R:R:L62	R:R:P63	3.28	Yes	No	0	3	1
214	R:R:L62	R:R:R74	4.86	Yes	Yes	1	3	4
215	R:R:G67	R:R:Y65	7.24	No	No	0	2	3
216	R:R:Y65	R:R:Y71	19.86	No	No	0	3	3
217	R:R:P86	R:R:Y65	8.34	No	No	0	2	3
218	R:R:G69	R:R:P70	4.06	No	No	0	1	1
219	H:H:?3	R:R:Y71	7.36	No	No	0	0	3
220	R:R:C112	R:R:C72	7.28	Yes	No	1	9	9
221	R:R:C72	R:R:W118	14.37	No	Yes	1	9	9
222	H:H:?3	R:R:N73	29.57	No	No	0	0	4
223	R:R:D84	R:R:R74	14.29	No	Yes	0	4	4
224	R:R:G78	R:R:W76	8.44	No	Yes	0	5	8
225	R:R:D77	R:R:W82	12.28	No	Yes	1	9	9
226	R:R:D77	R:R:S129	5.89	No	Yes	1	9	7
227	R:R:D77	R:R:Y131	8.05	No	Yes	1	9	5
228	R:R:W79	R:R:Y98	5.79	Yes	Yes	1	6	4
229	R:R:F99	R:R:W79	11.02	Yes	Yes	1	5	6
230	R:R:W79	R:R:Y131	12.54	Yes	Yes	1	6	5
231	R:R:L80	R:R:W82	4.56	Yes	Yes	1	5	9
232	R:R:L80	R:R:Q93	11.98	Yes	No	1	5	6
233	R:R:L80	R:R:P96	8.21	Yes	Yes	1	5	9
234	R:R:L80	R:R:V108	4.47	Yes	Yes	1	5	7
235	R:R:L80	R:R:Y131	8.21	Yes	Yes	1	5	5
236	R:R:S91	R:R:W82	6.18	No	Yes	0	5	9
237	R:R:Q93	R:R:W82	18.62	No	Yes	1	6	9
238	R:R:V108	R:R:W82	4.9	Yes	Yes	1	7	9
239	R:R:K110	R:R:W82	23.21	No	Yes	1	8	9
240	R:R:S129	R:R:W82	7.41	Yes	Yes	1	7	9
241	R:R:P86	R:R:T85	3.5	No	Yes	1	2	7
242	R:R:T85	R:R:V89	4.76	Yes	No	1	7	5
243	R:R:C112	R:R:T85	5.07	Yes	Yes	1	9	7
244	R:R:T85	R:R:W118	8.49	Yes	Yes	1	7	9
245	R:R:P86	R:R:V89	7.07	No	No	1	2	5
246	R:R:L90	R:R:Y92	5.86	No	No	3	4	4
247	R:R:L90	R:R:T109	7.37	No	No	3	4	5
248	R:R:L90	R:R:Y111	8.21	No	No	0	4	4
249	R:R:K107	R:R:Y92	3.58	No	No	0	3	4
250	R:R:T109	R:R:Y92	4.99	No	No	3	5	4
251	R:R:F94	R:R:K107	16.13	No	No	0	3	3
252	R:R:C95	R:R:V108	3.42	No	Yes	0	9	7
253	R:R:C134	R:R:C95	7.28	No	No	0	9	9
254	R:R:P96	R:R:Y98	15.3	Yes	Yes	1	9	4
255	R:R:F102	R:R:P96	4.33	Yes	Yes	1	4	9
256	R:R:P96	R:R:Y131	4.17	Yes	Yes	1	9	5
257	R:R:F99	R:R:Y98	6.19	Yes	Yes	1	5	4
258	R:R:D101	R:R:F99	3.58	Yes	Yes	1	4	5
259	R:R:F102	R:R:F99	13.93	Yes	Yes	1	4	5
260	R:R:D101	R:R:F102	4.78	Yes	Yes	1	4	4
261	R:R:D101	R:R:N135	9.42	Yes	Yes	1	4	3
262	R:R:C134	R:R:F102	12.57	No	Yes	0	9	4
263	R:R:F102	R:R:N135	3.62	Yes	Yes	1	4	3
264	R:R:D103	R:R:P104	6.44	Yes	No	0	3	3
265	R:R:D103	R:R:S105	2.94	Yes	No	0	3	1
266	R:R:D103	R:R:E106	7.8	Yes	No	0	3	4
267	R:R:D103	R:R:K141	5.53	Yes	No	0	3	3
268	R:R:E294	R:R:P104	4.72	No	No	0	3	3
269	R:R:E106	R:R:F137	9.33	No	Yes	3	4	1
270	R:R:E106	R:R:K366	5.4	No	No	3	4	3
271	R:R:V108	R:R:Y131	13.88	Yes	Yes	1	7	5
272	R:R:N130	R:R:T109	8.77	Yes	No	3	8	5
273	R:R:K110	R:R:W118	15.08	No	Yes	1	8	9
274	R:R:K110	R:R:S129	7.65	No	Yes	1	8	7
275	R:R:D113	R:R:Y111	6.9	No	No	0	5	4
276	R:R:C112	R:R:W118	3.92	Yes	Yes	1	9	9
277	R:R:T127	R:R:W118	3.64	No	Yes	0	4	9
278	R:R:F119	R:R:W128	4.01	No	Yes	0	4	5
279	R:R:K120	R:R:N125	5.6	No	No	0	1	7
280	R:R:H121	R:R:P122	6.1	Yes	No	0	4	5
281	R:R:E123	R:R:H121	8.62	No	Yes	3	4	4
282	R:R:H121	R:R:W128	17.98	Yes	Yes	3	4	5
283	R:R:N124	R:R:R126	10.85	No	No	3	5	4
284	H:H:?4	R:R:N125	30.8	No	No	0	0	7
285	R:R:N130	R:R:W128	12.43	Yes	Yes	3	8	5
286	H:H:?2	R:R:W128	7.15	Yes	Yes	3	0	5
287	R:R:S129	R:R:Y131	10.17	Yes	Yes	1	7	5
288	R:R:N130	R:R:T132	8.77	Yes	No	3	8	6
289	H:H:?2	R:R:N130	22.18	Yes	Yes	3	0	8
290	R:R:C134	R:R:Y131	4.03	No	Yes	0	9	5
291	R:R:M133	R:R:T132	3.01	No	No	3	5	6
292	H:H:?2	R:R:T132	3.97	Yes	No	3	0	6
293	H:H:?2	R:R:M133	7.61	Yes	No	3	0	5
294	R:R:A136	R:R:F137	4.16	No	Yes	0	2	1
295	R:R:F137	R:R:K366	6.2	Yes	No	3	1	3
296	R:R:P139	R:R:T138	5.25	No	No	0	3	2
297	R:R:E140	R:R:P139	4.72	No	No	0	2	3
298	R:R:L142	R:R:Y146	11.72	No	No	7	2	2
299	R:R:K370	R:R:N144	8.39	No	No	5	4	4
300	R:R:N144	R:R:Y374	9.3	No	Yes	5	4	6
301	R:R:V147	R:R:Y374	7.57	No	Yes	0	4	6
302	R:R:D373	R:R:L148	5.43	No	Yes	0	5	5
303	R:R:L148	R:R:Y374	3.52	Yes	Yes	5	5	6
304	R:R:H377	R:R:L148	14.14	Yes	Yes	5	7	5
305	R:R:Y149	R:R:Y150	10.92	Yes	No	0	5	4
306	R:R:I153	R:R:Y149	6.04	No	Yes	0	7	5
307	R:R:L202	R:R:Y149	7.03	No	Yes	0	7	5
308	R:R:L151	R:R:S378	3	No	No	0	5	5
309	R:R:F382	R:R:L151	3.65	No	No	0	7	5
310	R:R:A152	R:R:H381	7.32	No	Yes	0	7	9
311	R:R:F382	R:R:G155	9.03	No	No	0	7	8
312	R:R:H156	R:R:S195	12.55	Yes	No	0	7	7
313	R:R:H156	R:R:I198	9.28	Yes	Yes	0	7	7
314	R:R:H156	R:R:H381	10.75	Yes	Yes	0	7	9
315	R:R:I199	R:R:S157	4.64	No	No	0	7	7
316	R:R:F385	R:R:L158	15.83	Yes	No	0	5	4
317	R:R:G384	R:R:S159	3.71	No	No	0	9	9
318	R:R:I160	R:R:S195	4.64	No	No	0	5	7
319	R:R:I160	R:R:M196	4.37	No	No	0	5	4
320	R:R:F161	R:R:I165	5.02	No	No	0	4	5
321	R:R:F385	R:R:T162	7.78	Yes	No	0	5	6
322	R:R:A388	R:R:T162	3.36	No	No	0	8	6
323	R:R:F393	R:R:T162	3.89	Yes	No	0	8	6
324	R:R:F188	R:R:L163	6.09	No	Yes	0	8	8
325	R:R:L163	R:R:Y191	3.52	Yes	Yes	0	8	8
326	R:R:I192	R:R:L163	2.85	No	Yes	0	7	8
327	R:R:A388	R:R:L163	3.15	No	Yes	0	8	8
328	R:R:I192	R:R:V164	4.61	No	No	0	7	4
329	R:R:I165	R:R:I169	2.94	No	No	0	5	8
330	R:R:F393	R:R:I165	3.77	Yes	No	0	8	5
331	R:R:A388	R:R:S166	3.42	No	No	0	8	9
332	R:R:C392	R:R:S166	6.89	Yes	No	11	9	9
333	R:R:F393	R:R:S166	6.61	Yes	No	11	8	9
334	R:R:K185	R:R:L167	4.23	No	No	0	6	6
335	R:R:F173	R:R:I169	3.77	Yes	No	0	7	8
336	R:R:C392	R:R:I169	4.91	Yes	No	0	9	8
337	R:R:F170	R:R:L176	4.87	Yes	Yes	0	8	9
338	R:R:F170	R:R:V181	10.49	Yes	Yes	0	8	9
339	R:R:F170	R:R:F188	4.29	Yes	No	0	8	8
340	R:R:C392	R:R:F170	6.98	Yes	Yes	0	9	8
341	R:R:F173	R:R:L176	3.65	Yes	Yes	0	7	9
342	R:R:F173	R:R:V402	6.55	Yes	No	0	7	5
343	R:R:F173	R:R:Q405	7.03	Yes	No	0	7	4
344	R:R:S175	R:R:T401	3.2	No	Yes	0	8	7
345	R:R:L176	R:R:V398	5.96	Yes	No	0	9	9
346	R:R:L176	R:R:T401	10.32	Yes	Yes	0	9	7
347	R:R:G177	R:R:V181	3.68	No	Yes	0	7	9
348	R:R:C178	R:R:R180	5.57	No	No	0	8	9
349	R:R:C178	R:R:V181	3.42	No	Yes	0	8	9
350	R:R:Q179	R:R:Y243	6.76	Yes	Yes	4	7	8
351	R:R:K256	R:R:Q179	4.07	No	Yes	0	5	7
352	R:R:Q179	R:R:Q257	3.84	Yes	Yes	4	7	5
353	R:R:L259	R:R:Q179	9.32	Yes	Yes	0	5	7
354	R:R:H184	R:R:R180	4.51	No	No	0	9	9
355	R:R:K185	R:R:V181	3.04	No	Yes	0	6	9
356	R:R:L259	R:R:T182	2.95	Yes	No	0	5	5
357	R:R:L183	R:R:W236	3.42	No	Yes	0	8	9
358	R:R:L183	R:R:Y243	7.03	No	Yes	0	8	8
359	R:R:L183	R:R:L259	6.92	No	Yes	0	8	5
360	R:R:E240	R:R:H184	11.08	No	No	0	9	9
361	R:R:H184	R:R:Y391	5.44	No	Yes	0	9	8
362	R:R:N186	R:R:W236	15.82	No	Yes	2	9	9
363	R:R:N186	R:R:Y263	9.3	No	No	2	9	5
364	R:R:N186	R:R:W267	7.91	No	Yes	2	9	9
365	R:R:M187	R:R:Y191	8.38	No	Yes	2	8	8
366	R:R:M187	R:R:M237	2.89	No	Yes	2	8	9
367	R:R:E240	R:R:M187	10.83	No	No	0	9	8
368	R:R:F188	R:R:V387	3.93	No	No	0	8	9
369	R:R:L189	R:R:L193	5.54	No	No	0	3	6
370	R:R:L189	R:R:W267	6.83	No	Yes	0	3	9
371	R:R:N233	R:R:T190	8.77	Yes	No	2	9	9
372	R:R:T190	R:R:W236	6.06	No	Yes	2	9	9
373	R:R:T190	R:R:W267	6.06	No	Yes	2	9	9
374	R:R:N233	R:R:Y191	16.28	Yes	Yes	2	9	8
375	R:R:M237	R:R:Y191	5.99	Yes	Yes	2	9	8
376	R:R:Q383	R:R:Y191	14.65	Yes	Yes	2	9	8
377	R:R:G384	R:R:Y191	8.69	No	Yes	0	9	8
378	R:R:V387	R:R:Y191	6.31	No	Yes	0	9	8
379	R:R:L193	R:R:M229	9.9	No	No	0	6	4
380	R:R:I198	R:R:N194	7.08	Yes	No	0	7	8
381	R:R:N194	R:R:N233	6.81	No	Yes	0	8	9
382	R:R:H226	R:R:I197	3.98	No	No	0	6	5
383	R:R:I197	R:R:M229	2.92	No	No	0	5	4
384	R:R:I198	R:R:L202	2.85	Yes	No	0	7	7
385	R:R:H226	R:R:I198	5.3	No	Yes	0	6	7
386	R:R:H201	R:R:V205	9.69	No	No	0	6	7
387	R:R:E204	R:R:V203	5.7	No	No	0	4	3
388	R:R:L291	R:R:V205	2.98	Yes	No	0	6	7
389	R:R:P207	R:R:V206	3.53	No	No	0	3	3
390	R:R:L211	R:R:N208	5.49	No	No	0	1	3
391	R:R:E210	R:R:R214	12.79	No	No	0	3	4
392	R:R:L211	R:R:R214	3.64	No	No	14	1	4
393	R:R:L211	R:R:P216	6.57	No	Yes	14	1	4
394	R:R:L291	R:R:V212	4.47	Yes	No	0	6	3
395	R:R:P216	R:R:R214	2.88	Yes	No	14	4	4
396	R:R:D215	R:R:K220	11.06	No	No	0	6	7
397	R:R:D215	R:R:N288	16.16	No	No	0	6	4
398	R:R:P216	R:R:S218	3.56	Yes	No	0	4	3
399	R:R:C219	R:R:P216	5.65	No	Yes	0	9	4
400	R:R:I221	R:R:V217	3.07	No	No	0	4	3
401	R:R:C219	R:R:C289	7.28	No	No	0	9	9
402	R:R:K220	R:R:N286	5.6	No	No	2	7	7
403	R:R:K220	R:R:W290	18.57	No	Yes	2	7	9
404	R:R:H223	R:R:Q227	13.6	No	No	0	5	7
405	R:R:H223	R:R:W290	11.64	No	Yes	0	5	9
406	R:R:F224	R:R:T274	5.19	No	No	0	5	6
407	R:R:F224	R:R:T275	3.89	No	No	0	5	3
408	R:R:H277	R:R:Q227	13.6	Yes	No	2	7	7
409	R:R:I301	R:R:Q227	6.86	No	No	2	7	7
410	R:R:C232	R:R:Y228	9.41	No	No	0	8	8
411	R:R:L271	R:R:Y228	5.86	No	No	0	4	8
412	R:R:T274	R:R:Y228	3.75	No	No	0	6	8
413	R:R:M230	R:R:Y234	3.59	No	Yes	2	6	7
414	R:R:H302	R:R:M230	5.25	Yes	No	2	6	6
415	R:R:A231	R:R:P270	3.74	No	Yes	0	5	9
416	R:R:C232	R:R:W267	5.22	No	Yes	0	8	9
417	R:R:C232	R:R:P270	5.65	No	Yes	0	8	9
418	R:R:M237	R:R:N233	4.21	Yes	Yes	2	9	9
419	R:R:M237	R:R:Y234	4.79	Yes	Yes	2	9	7
420	R:R:V305	R:R:Y234	12.62	No	Yes	2	7	7
421	R:R:L309	R:R:Y234	3.52	No	Yes	2	7	7
422	R:R:F356	R:R:Y234	14.44	Yes	Yes	2	7	7
423	R:R:F235	R:R:L265	3.65	Yes	Yes	0	5	7
424	R:R:F235	R:R:F269	7.5	Yes	Yes	6	5	3
425	R:R:F235	R:R:P270	4.33	Yes	Yes	6	5	9
426	R:R:C239	R:R:W236	7.84	No	Yes	0	7	9
427	R:R:W236	R:R:Y263	3.86	Yes	No	2	9	5
428	R:R:G266	R:R:W236	8.44	No	Yes	0	9	9
429	R:R:W236	R:R:W267	15.93	Yes	Yes	2	9	9
430	R:R:M237	R:R:Q383	8.16	Yes	Yes	2	9	9
431	R:R:I242	R:R:L238	7.14	Yes	Yes	0	7	8
432	R:R:A308	R:R:L238	4.73	No	Yes	0	7	8
433	R:R:L238	R:R:V311	2.98	Yes	No	0	8	6
434	R:R:L238	R:R:N312	4.12	Yes	No	0	8	9
435	R:R:C239	R:R:Y262	4.03	No	Yes	0	7	7
436	R:R:C239	R:R:L265	4.76	No	Yes	0	7	7
437	R:R:E240	R:R:L351	14.58	No	No	0	9	9
438	R:R:G241	R:R:N312	3.39	No	No	0	8	9
439	R:R:I242	R:R:Y262	4.84	Yes	Yes	4	7	7
440	R:R:F315	R:R:I242	3.77	No	Yes	0	8	7
441	R:R:L247	R:R:Y243	10.55	No	Yes	0	8	8
442	R:R:Q257	R:R:Y243	7.89	Yes	Yes	4	5	8
443	R:R:Y243	R:R:Y262	6.95	Yes	Yes	4	8	7
444	R:R:I248	R:R:L244	4.28	No	No	0	7	9
445	R:R:I319	R:R:L244	4.28	No	No	0	9	9
446	R:R:L244	R:R:L348	4.15	No	No	0	9	9
447	R:R:H245	R:R:V249	16.61	No	No	15	8	6
448	R:R:F315	R:R:H245	22.63	No	No	0	8	8
449	R:R:H245	R:R:N318	7.65	No	No	15	8	8
450	R:R:T246	R:R:V250	3.17	No	No	0	7	5
451	R:R:Q257	R:R:T246	8.5	Yes	No	0	5	7
452	R:R:E255	R:R:L247	6.63	No	No	0	6	8
453	R:R:I248	R:R:V322	3.07	No	No	0	7	8
454	R:R:V249	R:R:V250	3.21	No	No	0	6	5
455	R:R:N318	R:R:V249	8.87	No	No	15	8	6
456	R:R:Q257	R:R:Y262	6.76	Yes	Yes	4	5	7
457	R:R:R258	R:R:R260	25.59	No	No	4	5	3
458	R:R:R258	R:R:W261	3	No	Yes	4	5	2
459	R:R:L259	R:R:Y263	8.21	Yes	No	0	5	5
460	R:R:R260	R:R:W261	5	No	Yes	4	3	2
461	R:R:F269	R:R:P270	2.89	Yes	Yes	6	3	9
462	R:R:F269	R:R:V272	5.24	Yes	No	0	3	4
463	R:R:P273	R:R:V272	3.53	No	No	0	6	4
464	R:R:I301	R:R:T274	4.56	No	No	0	7	6
465	R:R:I276	R:R:I300	4.42	No	Yes	0	5	8
466	R:R:H277	R:R:R281	14.67	Yes	Yes	2	7	7
467	R:R:H277	R:R:L298	5.14	Yes	Yes	2	7	6
468	R:R:H277	R:R:I301	6.63	Yes	No	2	7	7
469	R:R:L297	R:R:T280	8.84	Yes	No	2	4	4
470	R:R:I300	R:R:T280	4.56	Yes	No	2	8	4
471	R:R:F285	R:R:R281	5.34	Yes	Yes	2	6	7
472	R:R:D287	R:R:R281	5.96	No	Yes	2	3	7
473	R:R:R281	R:R:W290	18.99	Yes	Yes	2	7	9
474	R:R:R281	R:R:T295	5.17	Yes	Yes	2	7	4
475	R:R:V283	R:R:Y284	10.09	No	No	0	3	2
476	R:R:D287	R:R:F285	7.17	No	Yes	2	3	6
477	R:R:F285	R:R:S292	7.93	Yes	No	2	6	4
478	R:R:F285	R:R:T295	16.86	Yes	Yes	2	6	4
479	R:R:N286	R:R:W290	5.65	No	Yes	2	7	9
480	R:R:D287	R:R:S292	5.89	No	No	2	3	4
481	R:R:C289	R:R:L291	3.17	No	Yes	0	9	6
482	R:R:E294	R:R:S292	2.87	No	No	0	3	4
483	R:R:L298	R:R:V293	2.98	Yes	Yes	2	6	6
484	R:R:L297	R:R:T295	4.42	Yes	Yes	2	4	4
485	R:R:H296	R:R:Y299	3.27	No	Yes	0	2	7
486	R:R:I300	R:R:L297	2.85	Yes	Yes	2	8	4
487	R:R:H302	R:R:L298	3.86	Yes	Yes	2	6	6
488	R:R:G303	R:R:P304	4.06	No	No	0	4	9
489	R:R:F356	R:R:L309	3.65	Yes	No	2	7	7
490	R:R:F315	R:R:V311	5.24	No	No	0	8	6
491	R:R:L352	R:R:N312	9.61	No	No	0	9	9
492	R:R:F313	R:R:L317	9.74	Yes	No	0	6	5
493	R:R:F313	R:R:V357	6.55	Yes	No	0	6	7
494	R:R:L316	R:R:V320	2.98	No	No	0	9	7
495	R:R:L316	R:R:L348	4.15	No	No	0	9	9
496	R:R:I354	R:R:L316	7.14	Yes	No	0	6	9
497	R:R:N318	R:R:R321	10.85	No	No	0	8	8
498	R:R:T345	R:R:V320	4.76	No	No	0	9	7
499	R:R:R321	R:R:V322	3.92	No	No	0	8	8
500	R:R:K326	R:R:V322	3.04	No	No	0	9	8
501	R:R:R328	R:R:V324	6.54	No	No	0	6	5
502	R:R:E329	R:R:T325	4.23	No	No	0	6	7
503	R:R:E329	R:R:K326	4.05	No	No	0	6	9
504	R:R:E332	R:R:M327	6.77	No	Yes	0	5	7
505	R:R:M327	R:R:M337	8.66	Yes	No	0	7	7
506	R:R:K340	R:R:M327	7.2	No	Yes	0	8	7
507	R:R:M337	R:R:R328	4.96	No	No	0	7	6
508	R:R:E332	R:R:H336	7.39	No	No	0	5	6
509	R:R:E334	R:R:M337	4.06	No	No	0	6	7
510	R:R:E334	R:R:Y338	7.86	No	No	0	6	7
511	R:R:H336	R:R:K340	5.24	No	No	0	6	8
512	R:R:I347	R:R:I390	4.42	No	No	13	8	8
513	R:R:I347	R:R:Y391	3.63	No	Yes	13	8	8
514	R:R:L348	R:R:Y391	3.52	No	Yes	0	9	8
515	R:R:P350	R:R:V349	5.3	No	No	0	9	8
516	R:R:I354	R:R:V349	7.68	Yes	No	0	6	8
517	R:R:F386	R:R:P350	2.89	No	No	0	5	9
518	R:R:I390	R:R:P350	5.08	No	No	0	8	9
519	R:R:L351	R:R:L352	5.54	No	No	0	9	9
520	R:R:L351	R:R:Y391	17.58	No	Yes	0	9	8
521	R:R:I354	R:R:L352	2.85	Yes	No	0	6	9
522	R:R:G353	R:R:Q355	3.29	No	Yes	2	9	8
523	R:R:F356	R:R:G353	3.01	Yes	No	2	7	9
524	R:R:F356	R:R:Q355	12.88	Yes	Yes	2	7	8
525	R:R:L379	R:R:Q355	7.99	No	Yes	0	5	8
526	R:R:Q355	R:R:Q383	11.52	Yes	Yes	2	8	9
527	R:R:F356	R:R:I380	5.02	Yes	No	0	7	6
528	R:R:F356	R:R:Q383	4.68	Yes	Yes	2	7	9
529	R:R:F359	R:R:V358	7.87	No	No	0	6	5
530	R:R:F359	R:R:M376	4.98	No	Yes	0	6	7
531	R:R:P363	R:R:R362	2.88	No	Yes	8	7	4
532	R:R:G369	R:R:R362	6	No	Yes	0	4	4
533	R:R:R362	R:R:Y372	8.23	Yes	No	8	4	7
534	R:R:D373	R:R:R362	13.1	No	Yes	0	5	4
535	R:R:L368	R:R:P363	3.28	No	No	0	3	7
536	R:R:P363	R:R:Y372	9.74	No	No	8	7	7
537	R:R:L368	R:R:N365	12.36	No	No	0	3	4
538	R:R:K370	R:R:Y374	4.78	No	Yes	5	4	6
539	R:R:M376	R:R:Y372	10.78	Yes	No	0	7	7
540	R:R:L379	R:R:V375	2.98	No	No	0	5	4
541	R:R:I380	R:R:M376	4.37	No	Yes	0	6	7
542	R:R:H377	R:R:H381	9.55	Yes	Yes	0	7	9
543	R:R:H381	R:R:I380	5.3	Yes	No	0	9	6
544	R:R:F382	R:R:F386	3.22	No	No	0	7	5
545	R:R:F385	R:R:F386	6.43	Yes	No	0	5	5
546	R:R:F385	R:R:T389	6.49	Yes	No	0	5	5
547	R:R:I390	R:R:Y391	8.46	No	Yes	13	8	8
548	R:R:C392	R:R:F393	5.59	Yes	Yes	11	9	8
549	R:R:N395	R:R:V398	8.87	No	No	0	9	9
550	R:R:E397	R:R:N396	3.94	No	No	0	9	6
551	R:R:N396	R:R:T400	4.39	No	No	0	6	4
552	R:R:R404	R:R:T401	3.88	No	Yes	12	7	7
553	R:R:Q405	R:R:T401	4.25	No	Yes	12	4	7
554	R:R:Q405	R:R:R404	5.84	No	No	12	4	7
555	E:E:L37	E:E:M33	2.83	No	Yes	0	8	8
556	R:R:L323	R:R:M327	2.83	No	Yes	0	9	7
557	E:E:K42	E:E:L39	2.82	No	No	0	3	1
558	L:L:F15	R:R:A145	2.77	Yes	No	0	0	4
559	R:R:A278	R:R:F224	2.77	No	No	0	6	5
560	R:R:E204	R:R:I200	2.73	No	No	0	4	6
561	E:E:E30	E:E:M33	2.71	No	Yes	0	7	8
562	R:R:H156	R:R:I199	2.65	Yes	No	0	7	7
563	R:R:E397	R:R:N395	2.63	No	No	0	9	9
564	R:R:F314	R:R:V310	2.62	No	No	0	5	4
565	R:R:A51	R:R:W76	2.59	No	Yes	0	8	8
566	E:E:H97	R:R:D57	2.52	Yes	No	0	9	4
567	R:R:F225	R:R:I221	2.51	No	No	0	5	4
568	R:R:F313	R:R:I354	2.51	Yes	Yes	0	6	6
569	E:E:T94	R:R:Y56	2.5	No	Yes	0	7	3
570	R:R:F137	R:R:M133	2.49	Yes	No	3	1	5
571	E:E:V51	E:E:W56	2.45	No	Yes	1	6	7
572	E:E:V53	E:E:W56	2.45	No	Yes	0	4	7
573	E:E:V137	R:R:W261	2.45	Yes	Yes	4	9	2
574	E:E:L129	R:R:F269	2.44	No	Yes	0	7	3
575	R:R:K47	R:R:Y98	2.39	No	Yes	0	4	4
576	R:R:L264	R:R:W261	2.28	No	Yes	0	3	2
577	R:R:F313	R:R:F314	2.14	Yes	No	0	6	5
578	R:R:G268	R:R:P270	2.03	No	Yes	0	6	9
579	R:R:C72	R:R:G116	1.96	No	No	1	9	9
580	R:R:C112	R:R:G116	1.96	Yes	No	1	9	9
581	E:E:A134	E:E:G135	1.95	No	No	0	8	7
582	L:L:P28	L:L:P29	1.95	No	No	0	0	0
583	R:R:A87	R:R:P70	1.87	No	No	0	4	1
584	R:R:G88	R:R:V89	1.84	No	No	0	8	5
585	R:R:G155	R:R:V154	1.84	No	No	0	8	6
586	E:E:G32	E:E:T31	1.82	No	No	0	3	7
587	L:L:G33	L:L:T36	1.82	No	Yes	0	0	0
588	E:E:A43	E:E:C40	1.81	No	Yes	0	2	9
589	E:E:A77	E:E:C82	1.81	No	No	0	7	9
590	E:E:G49	E:E:M48	1.75	No	Yes	0	3	9
591	R:R:A333	R:R:S335	1.71	No	No	0	5	6
592	E:E:V127	R:R:A307	1.7	No	No	0	7	3
593	R:R:G209	R:R:N208	1.7	No	No	0	3	3
594	R:R:A341	R:R:V324	1.7	No	No	0	9	5
595	R:R:C394	R:R:T389	1.69	No	No	0	5	5
596	R:R:M306	R:R:P360	1.68	No	No	0	4	5
597	R:R:E68	R:R:G69	1.64	No	No	0	1	1
598	L:L:P29	R:R:N135	1.63	No	Yes	0	0	3
599	E:E:A45	E:E:M48	1.61	No	Yes	0	5	9
600	L:L:A5	R:R:M376	1.61	No	Yes	0	0	7
601	E:E:V124	E:E:V128	1.6	No	No	0	4	4
602	R:R:V320	R:R:V324	1.6	No	No	0	7	5
603	R:R:A344	R:R:L323	1.58	No	No	0	9	9
604	E:E:I63	E:E:S60	1.55	No	No	0	6	7
605	E:E:I120	E:E:V124	1.54	No	No	0	5	4
606	R:R:I153	R:R:V203	1.54	No	No	0	7	3
607	R:R:I199	R:R:V203	1.54	No	No	0	7	3
608	R:R:K120	R:R:V117	1.52	No	No	0	1	5
609	R:R:K185	R:R:V171	1.52	No	No	0	6	4
610	R:R:M346	R:R:T345	1.51	No	No	0	8	9
611	R:R:K120	R:R:T127	1.5	No	No	0	1	4
612	R:R:G209	R:R:R213	1.5	No	No	0	3	2
613	R:R:L222	R:R:V205	1.49	No	No	0	6	7
614	R:R:N135	R:R:T138	1.46	Yes	No	0	3	2
615	R:R:A333	R:R:H336	1.46	No	No	0	5	6
616	R:R:G44	R:R:Y98	1.45	No	Yes	0	4	4
617	R:R:D83	R:R:T85	1.45	No	Yes	0	5	7
618	R:R:I347	R:R:K343	1.45	No	No	0	8	8
619	E:E:M47	E:E:M48	1.44	No	Yes	0	4	9
620	R:R:F99	R:R:P100	1.44	Yes	No	0	5	4
621	R:R:E332	R:R:T330	1.41	No	No	0	5	5
622	E:E:M75	E:E:N71	1.4	No	No	0	1	4
623	R:R:M367	R:R:N365	1.4	No	No	0	4	4
624	R:R:K403	R:R:Q399	1.36	No	No	0	6	7
625	R:R:N396	R:R:Q399	1.32	No	No	0	6	7
626	E:E:E74	E:E:N78	1.31	No	No	0	5	1
627	R:R:F172	R:R:V171	1.31	No	No	0	2	4
628	E:E:D116	E:E:E117	1.3	No	No	0	6	4
629	R:R:D113	R:R:E114	1.3	No	No	0	5	2
630	R:R:A282	R:R:W290	1.3	No	Yes	0	3	9
631	R:R:F225	R:R:I197	1.26	No	No	0	5	5
632	E:E:F100	E:E:Q99	1.17	Yes	No	0	8	4

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	E:E:M33	4.47	4	0	8
2	E:E:C40	3.8025	4	1	9
3	E:E:F44	9.015	6	1	9
4	E:E:M48	6.77167	6	1	9
5	E:E:K55	11.4525	4	1	4
6	E:E:W56	4.8525	4	1	7
7	E:E:L59	7.5	4	1	7
8	E:E:E61	7.85	4	1	6
9	E:E:F69	7.792	5	1	8
10	E:E:E76	4.9325	4	1	6
11	E:E:W84	10.1967	6	1	9
12	E:E:F92	4.025	4	1	8
13	E:E:H97	7.148	5	1	9
14	E:E:F100	8.888	5	1	8
15	E:E:F101	8.404	5	1	9
16	E:E:P114	8.885	4	0	9
17	E:E:V137	5.1	4	4	9
18	L:L:C2	5.262	5	2	0
19	L:L:T4	3.805	4	2	0
20	L:L:T6	5.75667	6	2	0
21	L:L:C7	6.29	4	2	0
22	L:L:Q10	4.555	4	2	0
23	L:L:F15	9.535	4	0	0
24	L:L:L16	4.4525	4	0	0
25	L:L:S20	4.215	4	7	0
26	L:L:T36	4.4725	4	10	0
27	L:L:Y37	6.43	5	1	0
28	L:L:?38	6.82	4	0	0
29	R:R:Q52	8.03	6	1	6
30	R:R:Y53	8.228	5	1	1
31	R:R:Y56	8.00667	6	1	3
32	R:R:L62	7.185	4	1	3
33	R:R:R74	10.4625	4	1	4
34	R:R:W76	9.27667	6	1	8
35	R:R:W79	9.542	5	1	6
36	R:R:L80	7.486	5	1	5
37	R:R:W82	11.0229	7	1	9
38	R:R:T85	4.654	5	1	7
39	R:R:P96	8.0025	4	1	9
40	R:R:Y98	7.38167	6	1	4
41	R:R:F99	9.05333	6	1	5
42	R:R:D101	6.6125	4	1	4
43	R:R:F102	7.62	6	1	4
44	R:R:D103	5.6775	4	0	3
45	R:R:V108	6.6675	4	1	7
46	R:R:C112	4.5575	4	1	9
47	R:R:W118	9.1	5	1	9
48	R:R:H121	10.2675	4	3	4
49	R:R:W128	10.57	5	3	5
50	R:R:S129	7.78	4	1	7
51	R:R:N130	13.0375	4	3	8
52	R:R:Y131	8.35625	8	1	5
53	R:R:N135	4.704	5	1	3
54	R:R:F137	5.545	4	3	1
55	R:R:L148	6.81	4	5	5
56	R:R:Y149	7.378	5	0	5
57	R:R:H156	8.8075	4	0	7
58	R:R:L163	3.9025	4	0	8
59	R:R:F170	6.6575	4	0	8
60	R:R:F173	5.25	4	0	7
61	R:R:L176	6.2	4	0	9
62	R:R:Q179	5.9975	4	4	7
63	R:R:V181	5.1575	4	0	9
64	R:R:Y191	9.11714	7	2	8
65	R:R:I198	6.1275	4	0	7
66	R:R:P216	4.665	4	14	4
67	R:R:N233	9.0175	4	2	9
68	R:R:Y234	7.95	6	2	7
69	R:R:F235	5.815	4	6	5
70	R:R:W236	8.76714	7	2	9
71	R:R:M237	5.208	5	2	9
72	R:R:L238	4.7425	4	0	8
73	R:R:I242	4.992	5	4	7
74	R:R:Y243	7.836	5	4	8
75	R:R:Q257	6.842	5	4	5
76	R:R:L259	6.85	4	0	5
77	R:R:W261	4.92667	6	4	2
78	R:R:Y262	5.87167	6	4	7
79	R:R:L265	3.9075	4	0	7
80	R:R:W267	8.39	5	2	9
81	R:R:F269	4.91333	6	6	3
82	R:R:P270	3.728	5	6	9
83	R:R:H277	10.01	4	2	7
84	R:R:R281	10.026	5	2	7
85	R:R:F285	10.382	5	2	6
86	R:R:W290	11.23	5	2	9
87	R:R:L291	3.7725	4	0	6
88	R:R:V293	5.08	4	2	6
89	R:R:T295	8.78	4	2	4
90	R:R:L297	5.26	4	2	4
91	R:R:L298	3.7875	4	2	6
92	R:R:Y299	4.6775	4	2	7
93	R:R:I300	4.0275	4	2	8
94	R:R:H302	5.96167	6	2	6
95	R:R:F313	5.235	4	0	6
96	R:R:M327	6.365	4	0	7
97	R:R:I354	5.045	4	0	6
98	R:R:Q355	8.92	4	2	8
99	R:R:F356	6.98143	7	2	7
100	R:R:R362	7.248	5	8	4
101	R:R:Y374	6.2925	4	5	6
102	R:R:M376	5.435	4	0	7
103	R:R:H377	8.305	4	5	7
104	R:R:H381	7.954	5	0	9
105	R:R:Q383	9.7525	4	2	9
106	R:R:F385	9.1325	4	0	5
107	R:R:Y391	7.726	5	13	8
108	R:R:C392	6.0925	4	11	9
109	R:R:F393	4.965	4	11	8
110	R:R:T401	5.4125	4	12	7
111	H:H:?2	10.2275	4	3	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	E:E:C40	E:E:E76	10.9566	4.56	Yes	Yes	1	9	6
2	E:E:C40	E:E:T73	13.482	3.38	Yes	No	1	9	9
3	E:E:F44	E:E:Y66	11.7708	4.13	Yes	No	0	9	9
4	E:E:H97	R:R:Y53	15.6225	8.71	Yes	Yes	1	9	1
5	E:E:H97	R:R:Y56	17.5973	5.44	Yes	Yes	1	9	3
6	E:E:I93	R:R:Y56	18.4048	14.51	No	Yes	1	9	3
7	E:E:I93	E:E:T73	14.2236	4.56	No	No	1	9	9
8	R:R:Q52	R:R:Y56	13.3916	6.76	Yes	Yes	1	6	3
9	E:E:W84	R:R:Q52	31.6297	3.29	Yes	Yes	1	9	6
10	R:R:W76	R:R:Y56	26.6765	8.68	Yes	Yes	1	8	3
11	E:E:W84	R:R:W76	16.3773	4.69	Yes	Yes	1	9	8
12	E:E:W84	L:L:Y37	48.7067	6.75	Yes	Yes	1	9	0
13	R:R:G78	R:R:W76	16.3382	8.44	No	Yes	0	5	8
14	L:L:Y37	R:R:G78	16.6048	4.35	Yes	No	0	0	5
15	L:L:?38	L:L:Y37	68.4183	2.9	Yes	Yes	0	0	0
16	L:L:?38	R:R:Y131	24.0609	5.8	Yes	Yes	0	0	5
17	L:L:?38	R:R:W128	91.8026	11.28	Yes	Yes	0	0	5
18	H:H:?2	R:R:W128	93.6587	7.15	Yes	Yes	3	0	5
19	H:H:?2	R:R:M133	96.2276	7.61	Yes	No	3	0	5
20	R:R:F137	R:R:M133	99.0921	2.49	Yes	No	3	1	5
21	R:R:E106	R:R:F137	99.5106	9.33	No	Yes	3	4	1
22	R:R:D103	R:R:E106	100	7.8	Yes	No	0	3	4
23	R:R:D103	R:R:P104	92.3044	6.44	Yes	No	0	3	3
24	R:R:E294	R:R:P104	67.585	4.72	No	No	0	3	3
25	L:L:R18	R:R:P104	25.0607	8.65	No	No	0	0	3
26	L:L:N14	L:L:R18	25.1501	6.03	No	No	0	0	0
27	L:L:N14	R:R:V293	25.1825	8.87	No	Yes	0	0	6
28	R:R:L298	R:R:V293	50.2424	2.98	Yes	Yes	2	6	6
29	L:L:K1	R:R:E294	58.7575	8.1	No	No	0	0	3
30	L:L:K1	R:R:V293	25.0682	4.55	No	Yes	2	0	6
31	L:L:K1	L:L:R11	33.8085	3.71	No	No	2	0	0
32	L:L:C7	L:L:R11	33.8779	4.18	Yes	No	2	0	0
33	L:L:C7	L:L:T4	12.3654	3.38	Yes	Yes	2	0	0
34	R:R:H277	R:R:I301	14.4613	6.63	Yes	No	2	7	7
35	R:R:I301	R:R:T274	14.3567	4.56	No	No	0	7	6
36	R:R:T274	R:R:Y228	13.8843	3.75	No	No	0	6	8
37	R:R:C232	R:R:Y228	13.6771	9.41	No	No	0	8	8
38	R:R:C239	R:R:W236	10.5293	7.84	No	Yes	0	7	9
39	R:R:H302	R:R:L298	44.1594	3.86	Yes	Yes	2	6	6
40	L:L:T6	R:R:H302	37.4487	8.21	Yes	Yes	2	0	6
41	L:L:T6	R:R:Y234	36.2108	8.74	Yes	Yes	2	0	7
42	R:R:M237	R:R:Y234	63.0462	4.79	Yes	Yes	2	9	7
43	R:R:M237	R:R:N233	11.9787	4.21	Yes	Yes	2	9	9
44	R:R:N233	R:R:T190	17.1652	8.77	Yes	No	2	9	9
45	R:R:T190	R:R:W236	15.9312	6.06	No	Yes	2	9	9
46	L:L:C7	R:R:H302	21.4751	10.32	Yes	Yes	2	0	6
47	L:L:T4	L:L:T6	13.3227	4.71	Yes	Yes	2	0	0
48	R:R:H302	R:R:M230	26.8137	5.25	Yes	No	2	6	6
49	R:R:M230	R:R:Y234	26.8517	3.59	No	Yes	2	6	7
50	L:L:T6	R:R:F356	14.0601	5.19	Yes	Yes	2	0	7
51	R:R:M237	R:R:Y191	20.9561	5.99	Yes	Yes	2	9	8
52	R:R:L163	R:R:Y191	21.7019	3.52	Yes	Yes	0	8	8
53	R:R:F356	R:R:Q383	13.3206	4.68	Yes	Yes	2	7	9
54	R:R:Q383	R:R:Y191	12.8521	14.65	Yes	Yes	2	9	8
55	R:R:F188	R:R:L163	11.1028	6.09	No	Yes	0	8	8
56	R:R:V387	R:R:Y191	11.5358	6.31	No	Yes	0	9	8
57	R:R:F188	R:R:V387	11.089	3.93	No	No	0	8	9
58	R:R:F170	R:R:F188	21.2887	4.29	Yes	No	0	8	8
59	R:R:F170	R:R:L176	13.4354	4.87	Yes	Yes	0	8	9
60	R:R:M187	R:R:M237	31.9535	2.89	No	Yes	2	8	9
61	R:R:E240	R:R:M187	32.928	10.83	No	No	0	9	8
62	R:R:E240	R:R:H184	11.5422	11.08	No	No	0	9	9
63	R:R:H184	R:R:Y391	10.7473	5.44	No	Yes	0	9	8
64	R:R:E240	R:R:L351	21.1993	14.58	No	No	0	9	9
65	R:R:L351	R:R:Y391	10.6766	17.58	No	Yes	0	9	8
66	R:R:L351	R:R:L352	10.4246	5.54	No	No	0	9	9
67	R:R:L348	R:R:Y391	18.3521	3.52	No	Yes	0	9	8
68	R:R:L316	R:R:L348	13.083	4.15	No	No	0	9	9
69	R:R:L316	R:R:V320	18.8727	2.98	No	No	0	9	7
70	R:R:V320	R:R:V324	16.1818	1.6	No	No	0	7	5
71	R:R:R328	R:R:V324	14.3869	6.54	No	No	0	6	5
72	R:R:M337	R:R:R328	13.4891	4.96	No	No	0	7	6
73	R:R:M327	R:R:M337	10.7947	8.66	Yes	No	0	7	7
74	E:E:Y66	R:R:Q52	17.8883	3.38	No	Yes	0	9	6

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
E:E:T70	E:E:W84	4.85	1	No	Yes	9	9	2	1
E:E:T70	R:R:Q52	8.5	1	No	Yes	9	6	2	2
E:E:E74	E:E:W84	29.44	1	No	Yes	5	9	1	1
E:E:E74	L:L:Y37	5.61	1	No	Yes	5	0	1	0
E:E:Y83	R:R:N124	6.98	3	No	No	6	5	2	1
E:E:Y83	R:R:R126	23.66	3	No	No	6	4	2	2
E:E:P85	E:E:W84	12.16	0	No	Yes	9	9	2	1
E:E:W84	L:L:Y37	6.75	1	Yes	Yes	9	0	1	0
E:E:W84	R:R:Q52	3.29	1	Yes	Yes	9	6	1	2
E:E:W84	R:R:W76	4.69	1	Yes	Yes	9	8	1	2
E:E:P85	R:R:R126	2.88	0	No	No	9	4	2	2
E:E:I123	R:R:Y299	3.63	0	No	Yes	9	7	2	1
L:L:K1	R:R:V293	4.55	2	No	Yes	0	6	0	1
L:L:K1	R:R:E294	8.1	2	No	No	0	3	0	1
L:L:C2	R:R:L298	3.17	2	Yes	Yes	0	6	0	1
L:L:C2	R:R:Y299	8.06	2	Yes	Yes	0	7	0	1
L:L:C2	R:R:H302	4.42	2	Yes	Yes	0	6	0	1
L:L:N3	R:R:W361	21.47	0	No	No	0	4	0	1
L:L:N3	R:R:R362	6.03	0	No	Yes	0	4	0	1
L:L:T4	R:R:Y299	3.75	2	Yes	Yes	0	7	0	1
L:L:T6	R:R:Y234	8.74	2	Yes	Yes	0	7	0	1
L:L:T6	R:R:H302	8.21	2	Yes	Yes	0	6	0	1
L:L:T6	R:R:V305	3.17	2	Yes	No	0	7	0	1
L:L:T6	R:R:M306	4.52	2	Yes	No	0	4	0	1
L:L:T6	R:R:F356	5.19	2	Yes	Yes	0	7	0	1
L:L:C7	R:R:H302	10.32	2	Yes	Yes	0	6	0	1
L:L:A8	R:R:H377	4.39	0	No	Yes	0	7	0	1
L:L:T9	R:R:H381	6.85	0	No	Yes	0	9	0	1
L:L:Q10	R:R:H226	6.18	2	Yes	No	0	6	0	1
L:L:Q10	R:R:M230	4.08	2	Yes	No	0	6	0	1
L:L:Q10	R:R:H302	3.71	2	Yes	Yes	0	6	0	1
L:L:R11	R:R:V293	3.92	2	No	Yes	0	6	0	1
L:L:L12	R:R:L148	4.15	5	No	Yes	0	5	0	1
L:L:L12	R:R:H377	5.14	5	No	Yes	0	7	0	1
L:L:A13	R:R:H201	2.93	0	No	No	0	6	0	1
L:L:N14	R:R:V293	8.87	0	No	Yes	0	6	0	1
L:L:F15	R:R:K141	18.61	0	Yes	No	0	3	0	1
L:L:F15	R:R:L142	4.87	0	Yes	No	0	2	0	1
L:L:L16	R:R:Y149	4.69	0	Yes	Yes	0	5	0	1
L:L:L16	R:R:V206	4.47	0	Yes	No	0	3	0	1
L:L:V17	R:R:V206	4.81	0	No	No	0	3	0	1
L:L:V17	R:R:L291	4.47	0	No	Yes	0	6	0	1
L:L:R18	R:R:P104	8.65	0	No	No	0	3	0	1
L:L:S20	R:R:L142	3	7	Yes	No	0	2	0	1
L:L:S20	R:R:Y146	6.36	7	Yes	No	0	2	0	1
L:L:N22	R:R:G209	5.09	0	No	No	0	3	0	1
L:L:L23	R:R:Y146	7.03	7	No	No	0	2	0	1
L:L:L23	R:R:Y149	8.21	7	No	Yes	0	5	0	1
L:L:T30	R:R:F99	18.16	1	No	Yes	0	5	0	1
L:L:T30	R:R:D101	8.67	1	No	Yes	0	4	0	1
L:L:T30	R:R:F102	6.49	1	No	Yes	0	4	0	1
L:L:V32	R:R:N135	7.39	0	No	Yes	0	3	0	1
L:L:S34	R:R:H121	8.37	3	No	Yes	0	4	0	1
L:L:S34	R:R:E123	4.31	3	No	No	0	4	0	1
L:L:S34	R:R:N124	8.94	3	No	No	0	5	0	1
L:L:Y37	R:R:G78	4.35	1	Yes	No	0	5	0	1
L:L:Y37	R:R:W79	12.54	1	Yes	Yes	0	6	0	1
L:L:?38	R:R:W128	11.28	0	Yes	Yes	0	5	0	1
L:L:?38	R:R:Y131	5.8	0	Yes	Yes	0	5	0	1
R:R:M48	R:R:W79	5.82	1	No	Yes	6	6	2	1
R:R:M48	R:R:Y98	13.17	1	No	Yes	6	4	2	2
R:R:Q52	R:R:W76	20.81	1	Yes	Yes	6	8	2	2
R:R:G78	R:R:W76	8.44	0	No	Yes	5	8	1	2
R:R:D77	R:R:S129	5.89	1	No	Yes	9	7	2	2
R:R:D77	R:R:Y131	8.05	1	No	Yes	9	5	2	1
R:R:W79	R:R:Y98	5.79	1	Yes	Yes	6	4	1	2
R:R:F99	R:R:W79	11.02	1	Yes	Yes	5	6	1	1
R:R:W79	R:R:Y131	12.54	1	Yes	Yes	6	5	1	1
R:R:L80	R:R:P96	8.21	1	Yes	Yes	5	9	2	2
R:R:L80	R:R:V108	4.47	1	Yes	Yes	5	7	2	2
R:R:L80	R:R:Y131	8.21	1	Yes	Yes	5	5	2	1
R:R:P96	R:R:Y98	15.3	1	Yes	Yes	9	4	2	2
R:R:F102	R:R:P96	4.33	1	Yes	Yes	4	9	1	2
R:R:P96	R:R:Y131	4.17	1	Yes	Yes	9	5	2	1
R:R:F99	R:R:Y98	6.19	1	Yes	Yes	5	4	1	2
R:R:D101	R:R:F99	3.58	1	Yes	Yes	4	5	1	1
R:R:F102	R:R:F99	13.93	1	Yes	Yes	4	5	1	1
R:R:D101	R:R:F102	4.78	1	Yes	Yes	4	4	1	1
R:R:D101	R:R:N135	9.42	1	Yes	Yes	4	3	1	1
R:R:C134	R:R:F102	12.57	0	No	Yes	9	4	2	1
R:R:F102	R:R:N135	3.62	1	Yes	Yes	4	3	1	1
R:R:D103	R:R:P104	6.44	0	Yes	No	3	3	2	1
R:R:D103	R:R:K141	5.53	0	Yes	No	3	3	2	1
R:R:E294	R:R:P104	4.72	0	No	No	3	3	1	1
R:R:V108	R:R:Y131	13.88	1	Yes	Yes	7	5	2	1
R:R:F119	R:R:W128	4.01	0	No	Yes	4	5	2	1
R:R:H121	R:R:P122	6.1	3	Yes	No	4	5	1	2
R:R:E123	R:R:H121	8.62	3	No	Yes	4	4	1	1
R:R:H121	R:R:W128	17.98	3	Yes	Yes	4	5	1	1
R:R:N124	R:R:R126	10.85	3	No	No	5	4	1	2
R:R:N130	R:R:W128	12.43	3	Yes	Yes	8	5	2	1
H:H:?2	R:R:W128	7.15	3	Yes	Yes	0	5	2	1
R:R:S129	R:R:Y131	10.17	1	Yes	Yes	7	5	2	1
H:H:?2	R:R:N130	22.18	3	Yes	Yes	0	8	2	2
R:R:C134	R:R:Y131	4.03	0	No	Yes	9	5	2	1
R:R:L142	R:R:Y146	11.72	7	No	No	2	2	1	1
R:R:D373	R:R:L148	5.43	0	No	Yes	5	5	2	1
R:R:L148	R:R:Y374	3.52	5	Yes	Yes	5	6	1	2
R:R:H377	R:R:L148	14.14	5	Yes	Yes	7	5	1	1
R:R:Y149	R:R:Y150	10.92	0	Yes	No	5	4	1	2
R:R:I153	R:R:Y149	6.04	0	No	Yes	7	5	2	1
R:R:L202	R:R:Y149	7.03	0	No	Yes	7	5	2	1
R:R:A152	R:R:H381	7.32	0	No	Yes	7	9	2	1
R:R:H156	R:R:I198	9.28	0	Yes	Yes	7	7	2	2
R:R:H156	R:R:H381	10.75	0	Yes	Yes	7	9	2	1
R:R:H226	R:R:I197	3.98	0	No	No	6	5	1	2
R:R:I198	R:R:L202	2.85	0	Yes	No	7	7	2	2
R:R:H226	R:R:I198	5.3	0	No	Yes	6	7	1	2
R:R:H201	R:R:V205	9.69	0	No	No	6	7	1	2
R:R:L291	R:R:V205	2.98	0	Yes	No	6	7	1	2
R:R:P207	R:R:V206	3.53	0	No	No	3	3	2	1
R:R:L291	R:R:V212	4.47	0	Yes	No	6	3	1	2
R:R:M230	R:R:Y234	3.59	2	No	Yes	6	7	1	1
R:R:H302	R:R:M230	5.25	2	Yes	No	6	6	1	1
R:R:M237	R:R:Y234	4.79	2	Yes	Yes	9	7	2	1
R:R:V305	R:R:Y234	12.62	2	No	Yes	7	7	1	1
R:R:L309	R:R:Y234	3.52	2	No	Yes	7	7	2	1
R:R:F356	R:R:Y234	14.44	2	Yes	Yes	7	7	1	1
R:R:M237	R:R:Q383	8.16	2	Yes	Yes	9	9	2	2
R:R:H277	R:R:L298	5.14	2	Yes	Yes	7	6	2	1
R:R:C289	R:R:L291	3.17	0	No	Yes	9	6	2	1
R:R:E294	R:R:S292	2.87	0	No	No	3	4	1	2
R:R:L298	R:R:V293	2.98	2	Yes	Yes	6	6	1	1
R:R:H296	R:R:Y299	3.27	0	No	Yes	2	7	2	1
R:R:H302	R:R:L298	3.86	2	Yes	Yes	6	6	1	1
R:R:F356	R:R:L309	3.65	2	Yes	No	7	7	1	2
R:R:G353	R:R:Q355	3.29	2	No	Yes	9	8	2	2
R:R:F356	R:R:G353	3.01	2	Yes	No	7	9	1	2
R:R:F356	R:R:Q355	12.88	2	Yes	Yes	7	8	1	2
R:R:Q355	R:R:Q383	11.52	2	Yes	Yes	8	9	2	2
R:R:F356	R:R:I380	5.02	2	Yes	No	7	6	1	2
R:R:F356	R:R:Q383	4.68	2	Yes	Yes	7	9	1	2
R:R:F359	R:R:M376	4.98	0	No	Yes	6	7	2	1
R:R:P363	R:R:R362	2.88	8	No	Yes	7	4	2	1
R:R:G369	R:R:R362	6	0	No	Yes	4	4	2	1
R:R:R362	R:R:Y372	8.23	8	Yes	No	4	7	1	2
R:R:D373	R:R:R362	13.1	0	No	Yes	5	4	2	1
R:R:P363	R:R:Y372	9.74	8	No	No	7	7	2	2
R:R:M376	R:R:Y372	10.78	0	Yes	No	7	7	1	2
R:R:I380	R:R:M376	4.37	0	No	Yes	6	7	2	1
R:R:H377	R:R:H381	9.55	5	Yes	Yes	7	9	1	1
R:R:H381	R:R:I380	5.3	0	Yes	No	9	6	1	2
L:L:F15	R:R:A145	2.77	0	Yes	No	0	4	0	1
R:R:G209	R:R:N208	1.7	0	No	No	3	3	1	2
R:R:M306	R:R:P360	1.68	0	No	No	4	5	1	2
L:L:P29	R:R:N135	1.63	0	No	Yes	0	3	0	1
L:L:A5	R:R:M376	1.61	0	No	Yes	0	7	0	1
R:R:G209	R:R:R213	1.5	0	No	No	3	2	1	2
R:R:N135	R:R:T138	1.46	1	Yes	No	3	2	1	2
R:R:F99	R:R:P100	1.44	1	Yes	No	5	4	1	2
E:E:E74	E:E:N78	1.31	1	No	No	5	1	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	7TZF_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	2.85
Number of Linked Nodes	492
Number of Links	632
Number of Hubs	111
Number of Links mediated by Hubs	395
Number of Communities	15
Number of Nodes involved in Communities	171
Number of Links involved in Communities	252

Path Summary
Number Of Nodes in MetaPath	75
Number Of Links MetaPath	74
Number of Shortest Paths	1229389
Length Of Smallest Path	3
Average Path Length	26.2859
Length of Longest Path	44
Minimum Path Strength	1.34
Average Path Strength	6.47884
Maximum Path Strength	23.01
Minimum Path Correlation	0.7
Average Path Correlation	0.962973
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	3.44828
Average % Of Corr. Nodes	38.686
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	55.1953
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain • G protein-coupled receptor-like
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain • G protein-coupled receptor-like
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	NH2
PDB Residues	L:L:?38
Environment Details	Open EMBL-EBI Page
Code	NH2
Name	AMINO GROUP
Synonyms
Identifier
Formula	H2 N
Molecular Weight	16.023
SMILES
PubChem	123329
Formal Charge	0
Total Atoms	3
Total Chiral Atoms	0
Total Bonds	2
Total Aromatic Bonds	0


Code	NAG
PDB Residues	H:H:?1 H:H:?2 H:H:?3 H:H:?4
Environment Details	Open EMBL-EBI Page
Code	NAG
Name	N-Acetylglucosamine
Synonyms	N-Acetylglucosamine
Identifier
Formula	C8 H15 N O6
Molecular Weight	221.208
SMILES
PubChem	24139
Formal Charge	0
Total Atoms	30
Total Chiral Atoms	5
Total Bonds	30
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	E
Protein	RAMP3
UniProt	O60896
Sequence	>7TZF_nogp_Chain_E E T G M L E R L P L C G K A F A D M M G K V D V W K W C N L S E F I V Y Y E S F T N C T E M E A N V V G C Y W P N P L A Q G F I T G I H R Q F F S N C T V D R V H L E D P P D E V L I P L I V I P V V L T V A M A G L V V W R S K R Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	R
Protein	Receptor
UniProt	P30988
Sequence	>7TZF_nogp_Chain_R Y V V G R K K M M D A Q Y K C Y D R M Q Q L P A Y Q G E G P Y C N R T W D G W L C W D D T P A G V L S Y Q F C P D Y F P D F D P S E K V T K Y C D E K G V W F K H P E N N R T W S N Y T M C N A F T P E K L K N A Y V L Y Y L A I V G H S L S I F T L V I S L G I F V F F R S L G C Q R V T L H K N M F L T Y I L N S M I I I I H L V E V V P N G E L V R R D P V S C K I L H F F H Q Y M M A C N Y F W M L C E G I Y L H T L I V V A V F T E K Q R L R W Y Y L L G W G F P L V P T T I H A I T R A V Y F N D N C W L S V E T H L L Y I I H G P V M A A L V V N F F F L L N I V R V L V T K M R E T H E A E S H M Y L K A V K A T M I L V P L L G I Q F V V F P W R P S N K M L G K I Y D Y V M H S L I H F Q G F F V A T I Y C F C N N E V Q T T V K R Q W A Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8F0K	B1	Peptide	Calcitonin	CT (AMY3)	Homo sapiens	Pramlintide Analogue San385	-	Gs/β1/γ2; RAMP3	1.9	2023-08-02	doi.org/10.1038/s41589-023-01393-4
	8F0K (No Gprot)	B1	Peptide	Calcitonin	CT (AMY3)	Homo sapiens	Pramlintide Analogue San385	-		1.9	2023-08-02	doi.org/10.1038/s41589-023-01393-4
	8F2A	B1	Peptide	Calcitonin	CT (AMY3)	Homo sapiens	Pramlintide Analogue San385	-	Gs/β1/γ2; RAMP3	2.2	2023-08-02	doi.org/10.1038/s41589-023-01393-4
	8F2A (No Gprot)	B1	Peptide	Calcitonin	CT (AMY3)	Homo sapiens	Pramlintide Analogue San385	-		2.2	2023-08-02	doi.org/10.1038/s41589-023-01393-4
	8F2B	B1	Peptide	Calcitonin	CT (AMY3)	Homo sapiens	Pramlintide Analogue San45	-	Gs/β1/γ2; RAMP3	2	2023-08-02	doi.org/10.1038/s41589-023-01393-4
	8F2B (No Gprot)	B1	Peptide	Calcitonin	CT (AMY3)	Homo sapiens	Pramlintide Analogue San45	-		2	2023-08-02	doi.org/10.1038/s41589-023-01393-4
	7TZF	B1	Peptide	Calcitonin	CT (AMY3)	Homo sapiens	Amylin	-	Gs/β1/γ2; RAMP3	2.4	2022-03-23	doi.org/10.1126/science.abm9609
	7TZF (No Gprot)	B1	Peptide	Calcitonin	CT (AMY3)	Homo sapiens	Amylin	-		2.4	2022-03-23	doi.org/10.1126/science.abm9609
	9BTW	B1	Peptide	Calcitonin	CT (AMY3)	Homo sapiens	Cagrilintide	-	Gs/β1/γ2; RAMP3	3	2025-04-16	To be published
	9BTW (No Gprot)	B1	Peptide	Calcitonin	CT (AMY3)	Homo sapiens	Cagrilintide	-		3	2025-04-16	To be published

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 7TZF_nogp.zip

You can click to copy the link of this page to easily come back here later

or use this QR code to link and share this page.

You can also read or download a guide explaining the meaning of all files and numerical data.