psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?3	L:L:S2	4.66	Yes	No	1	0	0
2	L:L:S2	R:R:N305	5.96	No	Yes	1	0	4
3	L:L:S2	R:R:S308	6.52	No	No	0	0	7
4	L:L:?3	L:L:F4	7.56	Yes	No	0	0	0
5	L:L:?3	R:R:E124	4.11	Yes	Yes	1	0	4
6	L:L:?3	R:R:V214	4.62	Yes	No	0	0	5
7	L:L:?3	R:R:R283	8.48	Yes	Yes	1	0	6
8	L:L:?3	R:R:F286	13.23	Yes	Yes	1	0	4
9	L:L:?3	R:R:N305	9.59	Yes	Yes	1	0	4
10	L:L:F4	R:R:F38	6.43	No	Yes	0	0	4
11	L:L:F4	R:R:L103	4.87	No	No	0	0	4
12	L:L:H9	L:L:L5	21.86	Yes	Yes	1	0	0
13	L:L:L5	R:R:F286	4.87	Yes	Yes	1	0	4
14	L:L:L5	R:R:S289	7.51	Yes	No	1	0	2
15	L:L:L5	R:R:F290	3.65	Yes	Yes	1	0	1
16	L:L:L5	R:R:Q302	5.32	Yes	No	0	0	3
17	L:L:P7	L:L:S6	3.56	No	No	1	0	0
18	L:L:S6	R:R:Y106	5.09	No	Yes	1	0	3
19	L:L:S6	R:R:E197	10.06	No	Yes	1	0	4
20	L:L:P7	R:R:Y106	5.56	No	Yes	1	0	3
21	L:L:E8	L:L:R11	17.45	No	No	0	0	0
22	L:L:E8	R:R:Q36	3.82	No	No	0	0	5
23	L:L:E8	R:R:R107	4.65	No	No	0	0	4
24	L:L:H9	L:L:Q13	6.18	Yes	No	0	0	0
25	L:L:H9	R:R:S289	4.18	Yes	No	1	0	2
26	L:L:H9	R:R:F290	4.53	Yes	Yes	1	0	1
27	L:L:Q10	R:R:L295	9.32	No	No	0	0	7
28	L:L:R11	L:L:V12	7.85	No	No	0	0	0
29	L:L:K16	L:L:Q13	5.42	No	No	0	0	0
30	L:L:R15	R:R:E187	4.65	No	No	0	0	3
31	L:L:K16	R:R:E202	4.05	No	No	0	0	6
32	R:R:L35	R:R:L43	6.92	No	Yes	0	4	5
33	R:R:F38	R:R:L37	8.53	Yes	No	0	4	5
34	R:R:L37	R:R:Q302	3.99	No	No	0	5	3
35	R:R:F38	R:R:L43	6.09	Yes	Yes	0	4	5
36	R:R:F38	R:R:Y303	7.22	Yes	No	0	4	1
37	R:R:F38	R:R:L306	14.61	Yes	No	0	4	4
38	R:R:L42	R:R:P39	3.28	No	No	0	3	4
39	R:R:L103	R:R:L43	4.15	No	Yes	0	4	5
40	R:R:L43	R:R:W104	13.67	Yes	No	0	5	4
41	R:R:T47	R:R:W104	12.13	No	No	0	6	4
42	R:R:L314	R:R:L53	4.15	No	No	0	5	7
43	R:R:F54	R:R:I58	3.77	No	No	0	7	6
44	R:R:F54	R:R:F93	5.36	No	Yes	0	7	6
45	R:R:F93	R:R:G57	4.52	Yes	No	0	6	8
46	R:R:G60	R:R:P320	4.06	No	No	0	8	9
47	R:R:A86	R:R:N61	4.69	No	No	0	9	9
48	R:R:D89	R:R:N61	6.73	Yes	No	0	9	9
49	R:R:N61	R:R:P320	11.4	No	No	0	9	9
50	R:R:L63	R:R:Y330	3.52	No	Yes	3	6	8
51	R:R:L63	R:R:V334	4.47	No	No	3	6	6
52	R:R:F87	R:R:M65	3.73	No	No	0	6	7
53	R:R:V67	R:R:Y330	3.79	No	Yes	0	8	8
54	R:R:N79	R:R:V68	5.91	No	No	0	8	7
55	R:R:F71	R:R:R70	5.34	No	No	0	5	5
56	R:R:L337	R:R:R70	4.86	No	No	0	5	5
57	R:R:E73	R:R:F71	4.66	No	No	0	6	5
58	R:R:F71	R:R:R336	10.69	No	No	0	5	3
59	R:R:R72	R:R:R75	5.33	No	No	0	6	7
60	R:R:E73	R:R:L74	3.98	No	No	0	6	8
61	R:R:N79	R:R:T76	7.31	No	No	0	8	7
62	R:R:E140	R:R:T77	5.64	No	No	0	9	7
63	R:R:K157	R:R:T77	6.01	No	No	0	3	7
64	R:R:E140	R:R:T78	8.47	No	No	0	9	8
65	R:R:A136	R:R:Y81	4	No	Yes	0	7	8
66	R:R:L137	R:R:Y81	4.69	No	Yes	0	8	8
67	R:R:E140	R:R:Y81	8.98	No	Yes	0	9	8
68	R:R:V160	R:R:Y81	6.31	No	Yes	0	7	8
69	R:R:V163	R:R:Y81	5.05	No	Yes	0	6	8
70	R:R:L137	R:R:L82	4.15	No	No	4	8	8
71	R:R:L82	R:R:Y323	5.86	No	Yes	4	8	9
72	R:R:L82	R:R:N324	5.49	No	No	0	8	7
73	R:R:I164	R:R:S84	4.64	No	No	0	7	9
74	R:R:M85	R:R:T133	9.03	No	No	0	9	8
75	R:R:I134	R:R:M85	4.37	Yes	No	0	8	9
76	R:R:F87	R:R:L91	7.31	No	No	0	6	7
77	R:R:C126	R:R:S88	5.16	No	No	0	8	8
78	R:R:S88	R:R:T130	4.8	No	No	0	8	9
79	R:R:S88	R:R:W168	6.18	No	No	0	8	9
80	R:R:D89	R:R:T130	4.34	Yes	No	0	9	9
81	R:R:A316	R:R:D89	4.63	No	Yes	0	9	9
82	R:R:D89	R:R:N319	4.04	Yes	No	0	9	9
83	R:R:C126	R:R:L91	4.76	No	No	0	8	7
84	R:R:F312	R:R:I92	6.28	Yes	No	0	7	7
85	R:R:F93	R:R:M96	4.98	Yes	Yes	1	6	7
86	R:R:F93	R:R:Y313	5.16	Yes	Yes	1	6	7
87	R:R:A316	R:R:F93	4.16	No	Yes	0	9	6
88	R:R:C95	R:R:V122	3.42	No	No	0	6	5
89	R:R:C95	R:R:S123	3.44	No	No	0	6	6
90	R:R:M96	R:R:Y313	10.78	Yes	Yes	1	7	7
91	R:R:F119	R:R:L98	7.31	Yes	No	0	4	5
92	R:R:D99	R:R:F119	4.78	No	Yes	1	6	4
93	R:R:D99	R:R:F309	4.78	No	Yes	1	6	5
94	R:R:D99	R:R:Y313	9.2	No	Yes	1	6	7
95	R:R:F111	R:R:V101	3.93	No	No	0	6	4
96	R:R:R102	R:R:Y106	8.23	Yes	Yes	1	5	3
97	R:R:R102	R:R:W109	6	Yes	Yes	1	5	7
98	R:R:F119	R:R:R102	9.62	Yes	Yes	1	4	5
99	R:R:Q120	R:R:R102	4.67	Yes	Yes	1	4	5
100	R:R:F309	R:R:L103	3.65	Yes	No	0	5	4
101	R:R:E197	R:R:Y106	6.73	Yes	Yes	1	4	3
102	R:R:P108	R:R:R107	8.65	No	No	0	4	4
103	R:R:E197	R:R:R107	4.65	Yes	No	0	4	4
104	R:R:C116	R:R:W109	6.53	No	Yes	1	9	7
105	R:R:F119	R:R:W109	4.01	Yes	Yes	1	4	7
106	R:R:C198	R:R:W109	7.84	No	Yes	1	9	7
107	R:R:D113	R:R:V184	8.76	No	No	0	4	5
108	R:R:C116	R:R:C198	7.28	No	No	1	9	9
109	R:R:F179	R:R:K117	6.2	No	No	0	5	7
110	R:R:F119	R:R:Q120	11.71	Yes	Yes	1	4	4
111	R:R:Q120	R:R:V182	12.89	Yes	No	0	4	4
112	R:R:C198	R:R:Q120	6.1	No	Yes	1	9	4
113	R:R:F121	R:R:F172	7.5	No	No	0	6	4
114	R:R:F121	R:R:F179	13.93	No	No	0	6	5
115	R:R:E124	R:R:Y128	5.61	Yes	Yes	0	4	6
116	R:R:E124	R:R:I178	8.2	Yes	No	0	4	4
117	R:R:E124	R:R:R283	6.98	Yes	Yes	1	4	6
118	R:R:F172	R:R:S125	6.61	No	No	0	4	5
119	R:R:T127	R:R:Y128	3.75	No	Yes	0	7	6
120	R:R:T127	R:R:W276	3.64	No	Yes	1	7	8
121	R:R:F312	R:R:T127	3.89	Yes	No	1	7	7
122	R:R:S217	R:R:Y128	3.82	No	Yes	0	6	6
123	R:R:F220	R:R:Y128	27.85	Yes	Yes	0	6	6
124	R:R:A129	R:R:W168	7.78	No	No	0	6	9
125	R:R:P224	R:R:V131	5.3	No	No	0	9	8
126	R:R:V131	R:R:W276	3.68	No	Yes	0	8	8
127	R:R:F220	R:R:L132	4.87	Yes	No	0	6	6
128	R:R:I134	R:R:L228	4.28	Yes	No	0	8	8
129	R:R:I134	R:R:N319	4.25	Yes	No	0	8	9
130	R:R:I134	R:R:Y323	3.63	Yes	Yes	0	8	9
131	R:R:P224	R:R:T135	3.5	No	No	0	9	7
132	R:R:C227	R:R:T135	3.38	No	No	0	6	7
133	R:R:L137	R:R:Y323	4.69	No	Yes	4	8	9
134	R:R:L231	R:R:S138	4.5	No	No	0	7	9
135	R:R:S138	R:R:Y232	7.63	No	Yes	0	9	9
136	R:R:R141	R:R:Y232	10.29	No	Yes	0	9	9
137	R:R:R141	R:R:Y323	6.17	No	Yes	0	9	9
138	R:R:C146	R:R:Y142	8.06	No	Yes	2	7	8
139	R:R:F147	R:R:Y142	4.13	Yes	Yes	2	6	8
140	R:R:L231	R:R:Y142	12.89	No	Yes	0	7	8
141	R:R:L234	R:R:Y142	5.86	No	Yes	0	5	8
142	R:R:I235	R:R:Y142	3.63	No	Yes	2	8	8
143	R:R:F143	R:R:F147	4.29	Yes	Yes	0	5	6
144	R:R:C146	R:R:F147	6.98	No	Yes	2	7	6
145	R:R:L149	R:R:P148	3.28	No	No	0	7	8
146	R:R:K161	R:R:L162	5.64	No	No	0	3	3
147	R:R:F172	R:R:W168	6.01	No	No	0	4	9
148	R:R:C173	R:R:S174	3.44	No	No	0	5	5
149	R:R:F220	R:R:S174	5.28	Yes	No	0	6	5
150	R:R:G176	R:R:P177	4.06	No	No	0	4	7
151	R:R:M213	R:R:P177	3.35	No	No	0	5	7
152	R:R:L181	R:R:L210	4.15	No	No	0	4	3
153	R:R:N196	R:R:V184	4.43	No	No	0	4	5
154	R:R:E185	R:R:R199	8.14	No	No	0	1	3
155	R:R:E185	R:R:T201	7.06	No	No	0	1	3
156	R:R:H186	R:R:P192	4.58	No	No	0	2	1
157	R:R:E187	R:R:T190	7.06	No	No	0	3	3
158	R:R:T190	R:R:T195	4.71	No	No	0	3	3
159	R:R:D191	R:R:P192	4.83	No	No	0	6	1
160	R:R:E197	R:R:R199	9.3	Yes	No	0	4	3
161	R:R:L210	R:R:P200	3.28	No	No	0	3	4
162	R:R:F286	R:R:P200	5.78	Yes	No	0	4	4
163	R:R:F203	R:R:R206	5.34	No	No	0	6	1
164	R:R:F290	R:R:V205	6.55	Yes	No	0	1	4
165	R:R:S287	R:R:T211	4.8	No	No	0	4	4
166	R:R:H280	R:R:S217	4.18	No	No	0	7	6
167	R:R:R283	R:R:S217	5.27	Yes	No	0	6	6
168	R:R:F222	R:R:S218	5.28	No	No	0	4	4
169	R:R:I219	R:R:L223	5.71	No	No	0	5	5
170	R:R:F221	R:R:F222	9.65	Yes	No	0	8	4
171	R:R:F221	R:R:L277	8.53	Yes	No	0	8	6
172	R:R:F221	R:R:H280	6.79	Yes	No	0	8	7
173	R:R:F272	R:R:P224	5.78	No	No	0	9	9
174	R:R:L228	R:R:Y232	4.69	No	Yes	0	8	9
175	R:R:F272	R:R:L228	4.87	No	No	0	9	8
176	R:R:L265	R:R:Y232	5.86	No	Yes	0	8	9
177	R:R:V269	R:R:Y232	5.05	No	Yes	0	8	9
178	R:R:L234	R:R:R237	4.86	No	No	0	5	4
179	R:R:R237	R:R:R241	8.53	No	No	0	4	5
180	R:R:K238	R:R:R242	3.71	No	No	0	5	5
181	R:R:H258	R:R:L239	7.71	No	Yes	2	6	8
182	R:R:R244	R:R:W240	7	No	No	0	4	4
183	R:R:R242	R:R:R254	8.53	No	No	2	5	5
184	R:R:H258	R:R:R242	9.03	No	No	2	6	5
185	R:R:R243	R:R:R254	8.53	No	No	0	3	5
186	R:R:D255	R:R:R243	5.96	No	No	0	1	3
187	R:R:L253	R:R:N257	4.12	No	No	0	2	5
188	R:R:H258	R:R:R254	9.03	No	No	2	6	5
189	R:R:Q256	R:R:Q260	3.84	No	No	0	4	7
190	R:R:L322	R:R:V267	4.47	Yes	No	0	8	6
191	R:R:L322	R:R:V268	4.47	Yes	No	0	8	8
192	R:R:F272	R:R:W276	9.02	No	Yes	0	9	8
193	R:R:C275	R:R:W276	3.92	No	Yes	0	9	8
194	R:R:C275	R:R:S315	6.89	No	No	0	9	9
195	R:R:F279	R:R:W276	10.02	Yes	Yes	1	6	8
196	R:R:F312	R:R:W276	4.01	Yes	Yes	1	7	8
197	R:R:L311	R:R:P278	3.28	No	No	0	7	9
198	R:R:F279	R:R:H280	7.92	Yes	No	0	6	7
199	R:R:F279	R:R:R283	8.55	Yes	Yes	1	6	6
200	R:R:F279	R:R:S308	5.28	Yes	No	0	6	7
201	R:R:F279	R:R:F312	5.36	Yes	Yes	1	6	7
202	R:R:G282	R:R:N305	5.09	No	Yes	0	4	4
203	R:R:K288	R:R:Y284	7.17	No	No	0	4	5
204	R:R:F286	R:R:F290	4.29	Yes	Yes	1	4	1
205	R:R:E291	R:R:K288	4.05	No	No	0	1	4
206	R:R:I297	R:R:K288	4.36	No	No	0	1	4
207	R:R:A298	R:R:S289	3.42	No	No	0	3	2
208	R:R:E291	R:R:P292	4.72	No	No	0	1	2
209	R:R:I297	R:R:S294	4.64	No	No	0	1	6
210	R:R:Q299	R:R:Q302	7.68	No	No	0	1	3
211	R:R:N305	R:R:S301	4.47	Yes	No	0	4	4
212	R:R:F309	R:R:Y313	10.32	Yes	Yes	1	5	7
213	R:R:F312	R:R:Y313	13.41	Yes	Yes	1	7	7
214	R:R:N324	R:R:Y330	19.77	No	Yes	0	7	8
215	R:R:V334	R:R:Y330	6.31	No	Yes	3	6	8
216	R:R:E341	R:R:F335	9.33	No	No	0	3	3
217	R:R:N196	R:R:P192	3.26	No	No	0	4	1
218	R:R:C50	R:R:M96	3.24	No	Yes	0	6	7
219	R:R:S174	R:R:V170	3.23	No	No	0	5	4
220	R:R:S287	R:R:V214	3.23	No	No	0	4	5
221	R:R:F143	R:R:R150	3.21	Yes	No	0	5	5
222	R:R:V154	R:R:V155	3.21	No	No	0	4	7
223	R:R:S84	R:R:T133	3.2	No	No	0	9	8
224	R:R:T229	R:R:V225	3.17	No	No	0	5	6
225	R:R:C304	R:R:L285	3.17	No	Yes	0	5	4
226	R:R:P108	R:R:Q105	3.16	No	No	0	4	4
227	R:R:A40	R:R:L35	3.15	No	No	0	2	4
228	R:R:A333	R:R:L74	3.15	No	No	0	6	8
229	R:R:L285	R:R:S301	3	Yes	No	0	4	4
230	R:R:L338	R:R:V334	2.98	No	No	0	7	6
231	R:R:L239	R:R:T261	2.95	Yes	No	0	8	8
232	R:R:I145	R:R:I235	2.94	No	No	2	9	8
233	R:R:I321	R:R:I325	2.94	No	No	0	6	6
234	R:R:N324	R:R:T64	2.92	No	No	0	7	9
235	R:R:I325	R:R:M326	2.92	No	No	0	6	7
236	R:R:M264	R:R:M326	2.89	No	No	0	8	7
237	L:L:V12	R:R:E187	2.85	No	No	0	0	3
238	R:R:I58	R:R:L90	2.85	No	No	0	6	7
239	R:R:I167	R:R:L132	2.85	No	No	0	7	6
240	R:R:I145	R:R:L239	2.85	No	Yes	2	9	8
241	R:R:I235	R:R:L239	2.85	No	Yes	2	8	8
242	R:R:I300	R:R:L285	2.85	No	Yes	0	2	4
243	R:R:L181	R:R:M213	2.83	No	No	0	4	5
244	R:R:K117	R:R:L114	2.82	No	No	0	7	4
245	R:R:P39	R:R:Y303	2.78	No	No	0	4	1
246	R:R:L62	R:R:L90	2.77	No	No	0	3	7
247	R:R:A317	R:R:F93	2.77	No	Yes	0	7	6
248	R:R:A175	R:R:F121	2.77	No	No	0	7	6
249	R:R:E296	R:R:I300	2.73	No	No	0	2	2
250	R:R:K263	R:R:Q260	2.71	No	No	0	7	7
251	R:R:R206	R:R:S207	2.64	No	No	0	1	3
252	R:R:F309	R:R:V46	2.62	Yes	No	0	5	4
253	R:R:F143	R:R:V139	2.62	Yes	No	0	5	7
254	R:R:A44	R:R:W104	2.59	No	No	0	4	4
255	L:L:Q10	L:L:Q14	2.56	No	No	0	0	0
256	R:R:S327	R:R:Y330	2.54	No	Yes	0	8	8
257	R:R:V268	R:R:Y232	2.52	No	Yes	0	8	9
258	R:R:F220	R:R:I219	2.51	Yes	No	0	6	5
259	R:R:F221	R:R:I273	2.51	Yes	No	0	8	6
260	L:L:H9	L:L:Q10	2.47	Yes	No	0	0	0
261	R:R:S218	R:R:W215	2.47	No	No	0	4	4
262	R:R:V101	R:R:W109	2.45	No	Yes	0	4	7
263	R:R:V184	R:R:W109	2.45	No	Yes	0	5	7
264	R:R:F93	R:R:L53	2.44	Yes	No	0	6	7
265	R:R:F309	R:R:L100	2.44	Yes	No	0	5	7
266	R:R:F179	R:R:L118	2.44	No	No	0	5	5
267	R:R:L74	R:R:Y330	2.34	No	Yes	0	8	8
268	R:R:L285	R:R:Y284	2.34	Yes	No	0	4	5
269	R:R:A48	R:R:G45	1.95	No	No	0	5	6
270	R:R:A59	R:R:G60	1.95	No	No	0	3	8
271	R:R:A40	R:R:P41	1.87	No	No	0	2	2
272	L:L:G1	R:R:S123	1.86	No	No	0	0	6
273	R:R:G183	R:R:V182	1.84	No	No	0	4	4
274	R:R:G236	R:R:V262	1.84	No	No	0	5	7
275	R:R:A129	R:R:A171	1.79	No	No	0	6	8
276	R:R:P278	R:R:S308	1.78	No	No	0	9	7
277	R:R:G112	R:R:L115	1.71	No	No	0	8	5
278	R:R:G236	R:R:L265	1.71	No	No	0	5	8
279	R:R:A151	R:R:V153	1.7	No	No	0	6	4
280	R:R:M96	R:R:P97	1.68	Yes	No	0	7	7
281	R:R:E341	R:R:G339	1.64	No	No	0	3	5
282	R:R:A144	R:R:I145	1.62	No	No	0	8	9
283	R:R:V310	R:R:V46	1.6	No	No	0	5	4
284	R:R:V55	R:R:V56	1.6	No	No	0	5	6
285	R:R:V153	R:R:V154	1.6	No	No	0	4	4
286	R:R:V155	R:R:V160	1.6	No	No	0	7	7
287	R:R:V155	R:R:V163	1.6	No	No	0	7	6
288	R:R:V212	R:R:V216	1.6	No	No	0	6	5
289	R:R:T49	R:R:V310	1.59	No	No	0	5	5
290	R:R:T229	R:R:V230	1.59	No	No	0	5	4
291	R:R:T229	R:R:V269	1.59	No	No	0	5	8
292	R:R:A204	R:R:L181	1.58	No	No	0	4	4
293	R:R:A271	R:R:L322	1.58	No	Yes	0	6	8
294	R:R:T76	R:R:T78	1.57	No	No	0	7	8
295	R:R:K329	R:R:S327	1.53	No	No	0	6	8
296	L:L:G1	R:R:F312	1.51	No	Yes	0	0	7
297	R:R:F111	R:R:G112	1.51	No	No	0	6	8
298	R:R:L80	R:R:S83	1.5	No	No	0	5	6
299	R:R:G245	R:R:R244	1.5	No	No	0	1	4
300	R:R:L80	R:R:V68	1.49	No	No	0	5	7
301	R:R:L209	R:R:V180	1.49	No	No	0	4	4
302	R:R:L277	R:R:V281	1.49	No	No	0	6	7
303	R:R:F147	R:R:P148	1.44	Yes	No	0	6	8
304	R:R:K263	R:R:M264	1.44	No	No	0	7	8
305	R:R:I318	R:R:L314	1.43	No	No	0	7	5
306	R:R:I318	R:R:L322	1.43	No	Yes	0	7	8
307	R:R:I321	R:R:L322	1.43	No	Yes	0	6	8
308	R:R:A266	R:R:F270	1.39	No	No	0	5	5
309	R:R:L337	R:R:L66	1.38	No	No	0	5	3
310	R:R:L91	R:R:L94	1.38	No	No	0	7	5
311	R:R:D255	R:R:K259	1.38	No	No	0	1	5
312	R:R:L274	R:R:L311	1.38	No	No	0	5	7
313	R:R:N257	R:R:Q256	1.32	No	No	0	5	4
314	R:R:R75	R:R:V68	1.31	No	No	0	7	7
315	R:R:E185	R:R:N188	1.31	No	No	0	1	3
316	R:R:E202	R:R:N188	1.31	No	No	0	6	3
317	R:R:F226	R:R:V225	1.31	No	No	0	3	6
318	R:R:F270	R:R:V269	1.31	No	No	0	5	8
319	R:R:R159	R:R:T156	1.29	No	No	0	5	7
320	R:R:F143	R:R:K152	1.24	Yes	No	0	5	4
321	R:R:K328	R:R:R331	1.24	No	No	0	5	8
322	R:R:D191	R:R:W193	1.12	No	No	0	6	4
323	R:R:R241	R:R:R244	1.07	No	No	0	5	4
324	R:R:F335	R:R:R331	1.07	No	No	0	3	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:?3	7.46429	7	1	0
2	L:L:L5	8.642	5	1	0
3	L:L:H9	7.844	5	1	0
4	R:R:F38	8.576	5	0	4
5	R:R:L43	7.7075	4	0	5
6	R:R:Y81	5.806	5	0	8
7	R:R:D89	4.935	4	0	9
8	R:R:F93	4.19857	7	1	6
9	R:R:M96	5.17	4	1	7
10	R:R:R102	7.13	4	1	5
11	R:R:Y106	6.4025	4	1	3
12	R:R:W109	4.88	6	1	7
13	R:R:F119	7.486	5	1	4
14	R:R:Q120	8.8425	4	1	4
15	R:R:E124	6.225	4	1	4
16	R:R:Y128	10.2575	4	0	6
17	R:R:I134	4.1325	4	0	8
18	R:R:Y142	6.914	5	2	8
19	R:R:F143	2.84	4	0	5
20	R:R:F147	4.21	4	2	6
21	R:R:E197	7.685	4	1	4
22	R:R:F220	10.1275	4	0	6
23	R:R:F221	6.87	4	0	8
24	R:R:Y232	6.00667	6	0	9
25	R:R:L239	4.09	4	2	8
26	R:R:W276	5.715	6	1	8
27	R:R:F279	7.426	5	1	6
28	R:R:R283	7.32	4	1	6
29	R:R:L285	2.84	4	0	4
30	R:R:F286	7.0425	4	1	4
31	R:R:F290	4.755	4	1	1
32	R:R:N305	6.2775	4	1	4
33	R:R:F309	4.762	5	1	5
34	R:R:F312	5.74333	6	1	7
35	R:R:Y313	9.774	5	1	7
36	R:R:L322	2.676	5	0	8
37	R:R:Y323	5.0875	4	4	9
38	R:R:Y330	6.37833	6	3	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:S2	R:R:S308	15.8636	6.52	No	No	0	0	7
2	L:L:?3	L:L:F4	30.925	7.56	Yes	No	0	0	0
3	L:L:F4	R:R:F38	12.9321	6.43	No	Yes	0	0	4
4	L:L:?3	R:R:F286	48.1447	13.23	Yes	Yes	1	0	4
5	L:L:L5	R:R:F286	19.88	4.87	Yes	Yes	1	0	4
6	L:L:H9	L:L:L5	13.9304	21.86	Yes	Yes	1	0	0
7	R:R:F286	R:R:F290	16.2906	4.29	Yes	Yes	1	4	1
8	L:L:H9	R:R:F290	13.0417	4.53	Yes	Yes	1	0	1
9	L:L:F4	R:R:L103	26.6432	4.87	No	No	0	0	4
10	R:R:F309	R:R:L103	40.1004	3.65	Yes	No	0	5	4
11	R:R:D99	R:R:F309	14.2189	4.78	No	Yes	1	6	5
12	R:R:D99	R:R:F119	69.2192	4.78	No	Yes	1	6	4
13	R:R:F119	R:R:R102	33.8623	9.62	Yes	Yes	1	4	5
14	R:R:R102	R:R:Y106	34.4682	8.23	Yes	Yes	1	5	3
15	R:R:E197	R:R:Y106	29.1996	6.73	Yes	Yes	1	4	3
16	R:R:E197	R:R:R107	22.5922	4.65	Yes	No	0	4	4
17	L:L:E8	R:R:R107	16.5676	4.65	No	No	0	0	4
18	L:L:E8	L:L:R11	12.4935	17.45	No	No	0	0	0
19	L:L:H9	L:L:Q13	14.1151	6.18	Yes	No	0	0	0
20	L:L:H9	L:L:Q10	10.7796	2.47	Yes	No	0	0	0
21	L:L:R11	L:L:V12	10.4391	7.85	No	No	0	0	0
22	L:L:K16	L:L:Q13	11.1085	5.42	No	No	0	0	0
23	R:R:L103	R:R:L43	17.7275	4.15	No	Yes	0	4	5
24	R:R:F309	R:R:Y313	31.6348	10.32	Yes	Yes	1	5	7
25	R:R:F93	R:R:Y313	66.0165	5.16	Yes	Yes	1	6	7
26	R:R:F93	R:R:L53	14.4959	2.44	Yes	No	0	6	7
27	R:R:L314	R:R:L53	13.0648	4.15	No	No	0	5	7
28	L:L:?3	R:R:R283	54.2443	8.48	Yes	Yes	1	0	6
29	R:R:F279	R:R:R283	55.4042	8.55	Yes	Yes	1	6	6
30	R:R:F279	R:R:F312	25.1197	5.36	Yes	Yes	1	6	7
31	R:R:F312	R:R:Y313	67.9151	13.41	Yes	Yes	1	7	7
32	R:R:F54	R:R:F93	10.1044	5.36	No	Yes	0	7	6
33	R:R:A316	R:R:F93	54.5329	4.16	No	Yes	0	9	6
34	R:R:A316	R:R:D89	53.8115	4.63	No	Yes	0	9	9
35	R:R:D89	R:R:N61	10.67	6.73	Yes	No	0	9	9
36	R:R:F279	R:R:W276	56.6622	10.02	Yes	Yes	1	6	8
37	R:R:F272	R:R:W276	100	9.02	No	Yes	0	9	8
38	R:R:F272	R:R:L228	99.6768	4.87	No	No	0	9	8
39	R:R:I134	R:R:L228	59.6111	4.28	Yes	No	0	8	8
40	R:R:I134	R:R:Y323	65.5433	3.63	Yes	Yes	0	8	9
41	R:R:L82	R:R:Y323	33.1064	5.86	No	Yes	4	8	9
42	R:R:L82	R:R:N324	33.5103	5.49	No	No	0	8	7
43	R:R:N324	R:R:Y330	29.6555	19.77	No	Yes	0	7	8
44	R:R:D89	R:R:T130	37.0766	4.34	Yes	No	0	9	9
45	R:R:S88	R:R:T130	35.1145	4.8	No	No	0	8	9
46	R:R:C126	R:R:S88	10.67	5.16	No	No	0	8	8
47	R:R:L137	R:R:Y323	44.1918	4.69	No	Yes	4	8	9
48	R:R:L137	R:R:Y81	44.7054	4.69	No	Yes	0	8	8
49	R:R:E140	R:R:Y81	22.3498	8.98	No	Yes	0	9	8
50	R:R:E140	R:R:T78	16.5561	8.47	No	No	0	9	8
51	R:R:T76	R:R:T78	14.5363	1.57	No	No	0	7	8
52	R:R:N79	R:R:T76	12.4935	7.31	No	No	0	8	7
53	R:R:N79	R:R:V68	10.4391	5.91	No	No	0	8	7
54	R:R:L74	R:R:Y330	16.1521	2.34	No	Yes	0	8	8
55	R:R:E73	R:R:L74	12.078	3.98	No	No	0	6	8
56	R:R:E73	R:R:F71	10.0237	4.66	No	No	0	6	5
57	R:R:S88	R:R:W168	23.1	6.18	No	No	0	8	9
58	R:R:I134	R:R:N319	37.0362	4.25	Yes	No	0	8	9
59	R:R:F119	R:R:W109	25.4544	4.01	Yes	Yes	1	4	7
60	R:R:V184	R:R:W109	14.294	2.45	No	Yes	0	5	7
61	R:R:F172	R:R:W168	16.9369	6.01	No	No	0	4	9
62	R:R:F121	R:R:F172	12.7705	7.5	No	No	0	6	4
63	R:R:T127	R:R:Y128	14.9691	3.75	No	Yes	0	7	6
64	R:R:F220	R:R:Y128	14.9518	27.85	Yes	Yes	0	6	6
65	R:R:L228	R:R:Y232	62.0001	4.69	No	Yes	0	8	9
66	R:R:S138	R:R:Y232	49.3508	7.63	No	Yes	0	9	9
67	R:R:L231	R:R:S138	47.7985	4.5	No	No	0	7	9
68	R:R:R141	R:R:Y232	14.5075	10.29	No	Yes	0	9	9
69	R:R:L231	R:R:Y142	46.2346	12.89	No	Yes	0	7	8
70	R:R:F147	R:R:Y142	12.6551	4.13	Yes	Yes	2	6	8
71	R:R:L234	R:R:Y142	11.0682	5.86	No	Yes	0	5	8
72	R:R:I235	R:R:Y142	21.5592	3.63	No	Yes	2	8	8
73	R:R:F286	R:R:P200	14.796	5.78	Yes	No	0	4	4
74	R:R:L210	R:R:P200	12.8397	3.28	No	No	0	3	4
75	R:R:L181	R:R:L210	10.7277	4.15	No	No	0	4	3
76	R:R:N196	R:R:V184	10.266	4.43	No	No	0	4	5
77	R:R:F279	R:R:H280	15.627	7.92	Yes	No	0	6	7
78	R:R:F221	R:R:H280	15.9097	6.79	Yes	No	0	8	7
79	R:R:V269	R:R:Y232	12.7994	5.05	No	Yes	0	8	9
80	R:R:I235	R:R:L239	16.1752	2.85	No	Yes	2	8	8
81	R:R:H258	R:R:L239	12.8801	7.71	No	Yes	2	6	8
82	R:R:V268	R:R:Y232	19.6607	2.52	No	Yes	0	8	9
83	R:R:L322	R:R:V268	18.5181	4.47	Yes	No	0	8	8
84	R:R:I321	R:R:L322	17.6006	1.43	No	Yes	0	6	8
85	R:R:I321	R:R:I325	15.6731	2.94	No	No	0	6	6
86	R:R:I325	R:R:M326	13.7342	2.92	No	No	0	6	7
87	R:R:M264	R:R:M326	11.7837	2.89	No	No	0	8	7
88	L:L:?3	R:R:N305	25.2005	9.59	Yes	Yes	1	0	4
89	R:R:N305	R:R:S301	32.4947	4.47	Yes	No	0	4	4
90	R:R:L285	R:R:S301	29.5978	3	Yes	No	0	4	4
91	R:R:L285	R:R:Y284	17.8949	2.34	Yes	No	0	4	5
92	R:R:K288	R:R:Y284	14.9403	7.17	No	No	0	4	5
93	R:R:V154	R:R:V155	12.4069	3.21	No	No	0	4	7
94	R:R:I318	R:R:L314	12.1819	1.43	No	No	0	7	5
95	R:R:D99	R:R:Y313	56.4776	9.2	No	Yes	1	6	7
96	R:R:F279	R:R:S308	20.0185	5.28	Yes	No	0	6	7
97	L:L:S2	R:R:N305	13.0475	5.96	No	Yes	1	0	4
98	R:R:D89	R:R:N319	36.4995	4.04	Yes	No	0	9	9
99	R:R:I318	R:R:L322	11.3913	1.43	No	Yes	0	7	8
100	R:R:F312	R:R:W276	39.6907	4.01	Yes	Yes	1	7	8
101	R:R:R141	R:R:Y323	13.7457	6.17	No	Yes	0	9	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:S2	R:R:N305	5.96	1	No	Yes	0	4	0	1
L:L:S2	R:R:S308	6.52	1	No	No	0	7	0	1
L:L:?3	R:R:E124	4.11	1	Yes	Yes	0	4	0	1
L:L:?3	R:R:V214	4.62	1	Yes	No	0	5	0	1
L:L:?3	R:R:R283	8.48	1	Yes	Yes	0	6	0	1
L:L:?3	R:R:F286	13.23	1	Yes	Yes	0	4	0	1
L:L:?3	R:R:N305	9.59	1	Yes	Yes	0	4	0	1
L:L:F4	R:R:F38	6.43	0	No	Yes	0	4	0	1
L:L:F4	R:R:L103	4.87	0	No	No	0	4	0	1
L:L:L5	R:R:F286	4.87	1	Yes	Yes	0	4	0	1
L:L:L5	R:R:S289	7.51	1	Yes	No	0	2	0	1
L:L:L5	R:R:F290	3.65	1	Yes	Yes	0	1	0	1
L:L:L5	R:R:Q302	5.32	1	Yes	No	0	3	0	1
L:L:S6	R:R:Y106	5.09	1	No	Yes	0	3	0	1
L:L:S6	R:R:E197	10.06	1	No	Yes	0	4	0	1
L:L:P7	R:R:Y106	5.56	1	No	Yes	0	3	0	1
L:L:E8	R:R:Q36	3.82	0	No	No	0	5	0	1
L:L:E8	R:R:R107	4.65	0	No	No	0	4	0	1
L:L:H9	R:R:S289	4.18	1	Yes	No	0	2	0	1
L:L:H9	R:R:F290	4.53	1	Yes	Yes	0	1	0	1
L:L:Q10	R:R:L295	9.32	0	No	No	0	7	0	1
L:L:R15	R:R:E187	4.65	0	No	No	0	3	0	1
L:L:K16	R:R:E202	4.05	0	No	No	0	6	0	1
R:R:F38	R:R:L37	8.53	0	Yes	No	4	5	1	2
R:R:L37	R:R:Q302	3.99	0	No	No	5	3	2	1
R:R:F38	R:R:L43	6.09	0	Yes	Yes	4	5	1	2
R:R:F38	R:R:Y303	7.22	0	Yes	No	4	1	1	2
R:R:F38	R:R:L306	14.61	0	Yes	No	4	4	1	2
R:R:L103	R:R:L43	4.15	0	No	Yes	4	5	1	2
R:R:F312	R:R:I92	6.28	1	Yes	No	7	7	1	2
R:R:C95	R:R:S123	3.44	0	No	No	6	6	2	1
R:R:R102	R:R:Y106	8.23	1	Yes	Yes	5	3	2	1
R:R:F309	R:R:L103	3.65	1	Yes	No	5	4	2	1
R:R:E197	R:R:Y106	6.73	1	Yes	Yes	4	3	1	1
R:R:P108	R:R:R107	8.65	0	No	No	4	4	2	1
R:R:E197	R:R:R107	4.65	1	Yes	No	4	4	1	1
R:R:E124	R:R:Y128	5.61	1	Yes	Yes	4	6	1	2
R:R:E124	R:R:I178	8.2	1	Yes	No	4	4	1	2
R:R:E124	R:R:R283	6.98	1	Yes	Yes	4	6	1	1
R:R:T127	R:R:Y128	3.75	1	No	Yes	7	6	2	2
R:R:T127	R:R:W276	3.64	1	No	Yes	7	8	2	2
R:R:F312	R:R:T127	3.89	1	Yes	No	7	7	1	2
R:R:S217	R:R:Y128	3.82	0	No	Yes	6	6	2	2
R:R:E187	R:R:T190	7.06	0	No	No	3	3	1	2
R:R:E197	R:R:R199	9.3	1	Yes	No	4	3	1	2
R:R:F286	R:R:P200	5.78	1	Yes	No	4	4	1	2
R:R:F290	R:R:V205	6.55	1	Yes	No	1	4	1	2
R:R:R283	R:R:S217	5.27	1	Yes	No	6	6	1	2
R:R:F279	R:R:W276	10.02	1	Yes	Yes	6	8	2	2
R:R:F312	R:R:W276	4.01	1	Yes	Yes	7	8	1	2
R:R:F279	R:R:R283	8.55	1	Yes	Yes	6	6	2	1
R:R:F279	R:R:S308	5.28	1	Yes	No	6	7	2	1
R:R:F279	R:R:F312	5.36	1	Yes	Yes	6	7	2	1
R:R:G282	R:R:N305	5.09	0	No	Yes	4	4	2	1
R:R:F286	R:R:F290	4.29	1	Yes	Yes	4	1	1	1
R:R:A298	R:R:S289	3.42	0	No	No	3	2	2	1
R:R:Q299	R:R:Q302	7.68	0	No	No	1	3	2	1
R:R:N305	R:R:S301	4.47	1	Yes	No	4	4	1	2
R:R:F309	R:R:Y313	10.32	1	Yes	Yes	5	7	2	2
R:R:F312	R:R:Y313	13.41	1	Yes	Yes	7	7	1	2
R:R:S287	R:R:V214	3.23	0	No	No	4	5	2	1
L:L:V12	R:R:E187	2.85	0	No	No	0	3	0	1
L:L:G1	R:R:S123	1.86	0	No	No	0	6	0	1
R:R:P278	R:R:S308	1.78	0	No	No	9	7	2	1
L:L:G1	R:R:F312	1.51	0	No	Yes	0	7	0	1
R:R:E202	R:R:N188	1.31	0	No	No	6	3	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	7W2Z_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.28
Number of Linked Nodes	300
Number of Links	324
Number of Hubs	38
Number of Links mediated by Hubs	146
Number of Communities	4
Number of Nodes involved in Communities	44
Number of Links involved in Communities	60

Path Summary
Number Of Nodes in MetaPath	102
Number Of Links MetaPath	101
Number of Shortest Paths	53244
Length Of Smallest Path	3
Average Path Length	12.5262
Length of Longest Path	28
Minimum Path Strength	1.155
Average Path Strength	6.07313
Maximum Path Strength	16.73
Minimum Path Correlation	0.7
Average Path Correlation	0.93544
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	4.16667
Average % Of Corr. Nodes	56.2931
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	43.871
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• protein tyrosine kinase activator activity • enzyme regulator activity • kinase activator activity • enzyme activator activity • molecular function activator activity • molecular function regulator activity • protein kinase activator activity • protein kinase regulator activity • kinase regulator activity • ghrelin receptor binding • protein binding • binding • signaling receptor binding • G protein-coupled receptor binding • hormone activity • growth hormone-releasing hormone activity • signaling receptor regulator activity • receptor ligand activity • signaling receptor activator activity • developmental process • multicellular organism development • multicellular organismal process • skeletal system development • connective tissue development • anatomical structure development • animal organ development • tissue development • cartilage development • system development • system process • regulation of biological process • digestive system process • regulation of system process
Gene Ontology	Biological Process	• developmental process • multicellular organism development • multicellular organismal process • skeletal system development • connective tissue development • anatomical structure development • animal organ development • tissue development • cartilage development • system development • system process • regulation of biological process • digestive system process • regulation of system process • regulation of gastric motility • biological regulation • regulation of digestive system process • digestion • gastric motility • regulation of multicellular organismal process • regulation of tumor necrosis factor production • regulation of cellular process • negative regulation of biological process • negative regulation of tumor necrosis factor production • cytokine production • regulation of cytokine production • negative regulation of cellular process • negative regulation of macromolecule metabolic process • regulation of biosynthetic process • negative regulation of metabolic process • tumor necrosis factor superfamily cytokine production • negative regulation of cytokine production • regulation of macromolecule metabolic process • gene expression • macromolecule biosynthetic process • tumor necrosis factor production • regulation of gene expression • negative regulation of gene expression • regulation of tumor necrosis factor superfamily cytokine production • biosynthetic process • negative regulation of biosynthetic process • negative regulation of macromolecule biosynthetic process • negative regulation of tumor necrosis factor superfamily cytokine production • metabolic process • cellular process • regulation of macromolecule biosynthetic process • macromolecule metabolic process • negative regulation of multicellular organismal process • regulation of metabolic process • interleukin-6 production • regulation of interleukin-6 production • negative regulation of interleukin-6 production • intestinal motility • positive regulation of small intestinal transit • positive regulation of biological process • positive regulation of digestive system process • positive regulation of multicellular organismal process • small intestinal transit • regulation of small intestinal transit • positive regulation of blood circulation • gastric mucosal blood circulation • regulation of gastric mucosal blood circulation • circulatory system process • regulation of blood circulation • positive regulation of gastric mucosal blood circulation • blood circulation • regulation of circadian sleep/wake cycle • negative regulation of circadian sleep/wake cycle, REM sleep • regulation of circadian rhythm • regulation of behavior • sleep • circadian sleep/wake cycle, sleep • rhythmic process • negative regulation of behavior • circadian sleep/wake cycle • rhythmic behavior • circadian rhythm • regulation of circadian sleep/wake cycle, REM sleep • negative regulation of circadian sleep/wake cycle, sleep • negative regulation of circadian rhythm • behavior • circadian behavior • circadian sleep/wake cycle, REM sleep • regulation of circadian sleep/wake cycle, sleep • circadian sleep/wake cycle process • regulation of multicellular organismal development • regulation of developmental process • regulation of bone development • positive regulation of developmental process • positive regulation of bone development • bone development • positive regulation of growth • regulation of growth • growth • positive regulation of growth rate • regulation of growth rate • monosaccharide metabolic process • carbohydrate metabolic process • hexose metabolic process • small molecule metabolic process • primary metabolic process • glucose metabolic process • response to electrical stimulus • response to stimulus • response to abiotic stimulus • trans-synaptic signaling • regulation of signaling • modulation of chemical synaptic transmission • signaling • cell-cell signaling • chemical synaptic transmission • cell communication • synaptic signaling • regulation of trans-synaptic signaling • anterograde trans-synaptic signaling • postsynaptic modulation of chemical synaptic transmission • regulation of cell communication • cell population proliferation • positive regulation of cell population proliferation • endothelial cell proliferation • positive regulation of epithelial cell proliferation • regulation of vascular endothelial cell proliferation • regulation of endothelial cell proliferation • regulation of cell population proliferation • positive regulation of endothelial cell proliferation • regulation of epithelial cell proliferation • vascular endothelial cell proliferation • epithelial cell proliferation • positive regulation of vascular endothelial cell proliferation • positive regulation of cellular process • positive regulation of cell communication • regulation of localization • nitrogen compound transport • localization • regulation of biological quality • regulation of peptide hormone secretion • positive regulation of corticotropin secretion • regulation of hormone levels • positive regulation of peptide hormone secretion • establishment of localization • regulation of secretion • endocrine hormone secretion • regulation of endocrine process • regulation of hormone secretion • regulation of peptide secretion • transport • positive regulation of secretion by cell • hormone secretion • regulation of corticotropin secretion • peptide secretion • secretion by cell • regulation of secretion by cell • positive regulation of hormone secretion • positive regulation of secretion • signal release • positive regulation of peptide secretion • secretion • regulation of transport • corticotropin secretion • regulation of peptide transport • export from cell • peptide transport • endocrine process • positive regulation of transport • peptide hormone secretion • hormone transport • positive regulation of signaling • nervous system development • cellular component organization • cellular component biogenesis • cell junction organization • cellular component assembly • cell junction assembly • synapse organization • cellular component organization or biogenesis • synapse assembly • regulation of cellular component organization • postsynapse organization • regulation of postsynapse organization • regulation of synapse organization • regulation of synapse structure or activity • steroid hormone secretion • organic hydroxy compound transport • cortisol secretion • lipid localization • lipid transport • lipid export from cell • macromolecule localization • glucocorticoid secretion • corticosteroid hormone secretion • cellular response to stimulus • cellular response to nitrogen compound • positive regulation of signal transduction • response to peptide hormone • regulation of signal transduction • cellular response to growth hormone stimulus • cell surface receptor protein tyrosine kinase signaling pathway • positive regulation of response to stimulus • cellular response to endogenous stimulus • regulation of growth hormone receptor signaling pathway • response to hormone • signal transduction • enzyme-linked receptor protein signaling pathway • cellular response to hormone stimulus • growth hormone receptor signaling pathway • cell surface receptor signaling pathway • response to endogenous stimulus • cellular response to peptide hormone stimulus • response to oxygen-containing compound • response to nitrogen compound • cellular response to oxygen-containing compound • response to growth hormone • cellular response to chemical stimulus • regulation of response to stimulus • response to chemical • positive regulation of growth hormone receptor signaling pathway • adult feeding behavior • adult behavior • feeding behavior • actin polymerization or depolymerization • organelle organization • actin cytoskeleton organization • actin filament organization • actin filament-based process • supramolecular fiber organization • cytoskeleton organization • positive regulation of smooth muscle contraction • intestine smooth muscle contraction • regulation of gastro-intestinal system smooth muscle contraction • positive regulation of small intestine smooth muscle contraction • smooth muscle contraction • regulation of smooth muscle contraction • regulation of small intestine smooth muscle contraction • small intestine smooth muscle contraction • gastro-intestinal system smooth muscle contraction • phasic smooth muscle contraction • muscle contraction • muscle system process • regulation of muscle system process • positive regulation of gastro-intestinal system smooth muscle contraction • regulation of muscle contraction • positive regulation of muscle contraction • response to nutrient levels • regulation of response to nutrient levels • regulation of response to food • response to food • positive regulation of steroid hormone secretion • regulation of glucocorticoid secretion • positive regulation of cortisol secretion • positive regulation of glucocorticoid secretion • regulation of steroid hormone secretion • positive regulation of corticosteroid hormone secretion • regulation of corticosteroid hormone secretion • positive regulation of lipid transport • regulation of cortisol secretion • regulation of lipid transport • positive regulation of lipid localization • regulation of lipid localization • acid secretion • gastric acid secretion • positive regulation of cytosolic calcium ion concentration • positive regulation of nervous system development • positive regulation of cellular component organization • regulation of nervous system development • regulation of synapse assembly • positive regulation of cellular component biogenesis • regulation of cellular component biogenesis • regulation of cell junction assembly • positive regulation of cell junction assembly • positive regulation of synapse assembly • response to estrogen • adipose tissue development • positive regulation of adipose tissue development • regulation of adipose tissue development • negative regulation of programmed cell death • regulation of apoptotic process • regulation of programmed cell death • cell death • negative regulation of apoptotic process • apoptotic process • programmed cell death • hormone-mediated signaling pathway • regulation of defense response • regulation of response to external stimulus • negative regulation of inflammatory response • defense response • negative regulation of response to stimulus • response to external stimulus • regulation of inflammatory response • response to stress • negative regulation of response to external stimulus • regulation of response to stress • negative regulation of defense response • inflammatory response • regulation of circadian sleep/wake cycle, non-REM sleep • circadian sleep/wake cycle, non-REM sleep • positive regulation of circadian sleep/wake cycle, non-REM sleep • positive regulation of behavior • positive regulation of circadian rhythm • positive regulation of circadian sleep/wake cycle, sleep • interleukin-1 production • regulation of interleukin-1 beta production • negative regulation of interleukin-1 beta production • negative regulation of interleukin-1 production • regulation of interleukin-1 production • interleukin-1 beta production • positive regulation of appetite • positive regulation of response to food • regulation of appetite • positive regulation of response to nutrient levels • negative regulation of protein transport • establishment of protein localization • negative regulation of transport • negative regulation of secretion • negative regulation of hormone secretion • negative regulation of secretion by cell • intracellular protein localization • negative regulation of peptide hormone secretion • establishment of protein localization to extracellular region • negative regulation of establishment of protein localization • protein secretion • regulation of protein secretion • negative regulation of protein secretion • regulation of protein localization • negative regulation of signaling • negative regulation of cell communication • protein localization to extracellular region • negative regulation of peptide secretion • negative regulation of protein localization • regulation of establishment of protein localization • regulation of protein transport • negative regulation of insulin secretion • protein transport • regulation of insulin secretion • insulin secretion • regulation of postsynaptic membrane potential • chemical synaptic transmission, postsynaptic • nervous system process • excitatory postsynaptic potential • regulation of membrane potential • homeostatic process • adaptive thermogenesis • multicellular organismal-level homeostasis • regulation of cold-induced thermogenesis • cold-induced thermogenesis • temperature homeostasis • positive regulation of cold-induced thermogenesis • positive regulation of establishment of protein localization • carbohydrate homeostasis • establishment of localization in cell • positive regulation of insulin secretion involved in cellular response to glucose stimulus • positive regulation of insulin secretion • intracellular glucose homeostasis • cellular response to carbohydrate stimulus • chemical homeostasis • response to glucose • glucose homeostasis • positive regulation of protein localization • insulin secretion involved in cellular response to glucose stimulus • cellular localization • positive regulation of protein transport • response to monosaccharide • response to carbohydrate • cellular response to hexose stimulus • intracellular chemical homeostasis • cellular response to monosaccharide stimulus • cellular response to glucose stimulus • positive regulation of protein secretion • response to hexose • cellular homeostasis • regulation of cellular localization • regulation of insulin secretion involved in cellular response to glucose stimulus • intracellular signal transduction • regulation of intracellular signal transduction • intracellular signaling cassette • positive regulation of MAPK cascade • positive regulation of intracellular signal transduction • regulation of MAPK cascade • MAPK cascade • plasma membrane bounded cell projection organization • cellular developmental process • cell projection organization • cell development • neuron projection development • generation of neurons • neurogenesis • neuron differentiation • dendrite development • cell differentiation • neuron development • multi-multicellular organism process • placenta development • reproductive process • maternal process involved in female pregnancy • multicellular organismal reproductive process • developmental process involved in reproduction • maternal placenta development • female pregnancy • multi-organism reproductive process • decidualization • regulation of multicellular organism growth • regulation of developmental growth • developmental growth • positive regulation of multicellular organism growth • multicellular organism growth • positive regulation of developmental growth • regulation of sprouting angiogenesis • angiogenesis • regulation of vasculature development • tube morphogenesis • positive regulation of sprouting angiogenesis • regulation of anatomical structure morphogenesis • blood vessel development • blood vessel morphogenesis • tube development • positive regulation of angiogenesis • sprouting angiogenesis • vasculature development • circulatory system development • anatomical structure morphogenesis • positive regulation of vasculature development • regulation of angiogenesis • anatomical structure formation involved in morphogenesis • negative regulation of locomotion • regulation of locomotion • locomotion • regulation of eating behavior • positive regulation of feeding behavior • eating behavior • positive regulation of eating behavior • regulation of feeding behavior • G protein-coupled receptor signaling pathway • negative regulation of blood vessel morphogenesis • negative regulation of developmental process • negative regulation of angiogenesis • negative regulation of vasculature development • growth hormone secretion • regulation of growth hormone secretion • positive regulation of growth hormone secretion • negative regulation of cell population proliferation • negative regulation of endothelial cell proliferation • negative regulation of epithelial cell proliferation • transmission of nerve impulse • regulation of nervous system process • regulation of transmission of nerve impulse • cellular anatomical structure • synapse • cell junction • glutamatergic synapse • membrane-bounded organelle • intracellular anatomical structure • membrane-enclosed lumen • intracellular membrane-bounded organelle • endomembrane system • intracellular organelle lumen • endoplasmic reticulum lumen • intracellular organelle • organelle lumen • organelle
Gene Ontology	Cellular Component	• cellular anatomical structure • synapse • cell junction • glutamatergic synapse • membrane-bounded organelle • intracellular anatomical structure • membrane-enclosed lumen • intracellular membrane-bounded organelle • endomembrane system • intracellular organelle lumen • endoplasmic reticulum lumen • intracellular organelle • organelle lumen • organelle • endoplasmic reticulum • cytoplasm • axon • cell projection • neuron projection • plasma membrane bounded cell projection • extracellular region • extracellular space • postsynapse • intracellular vesicle • cytoplasmic vesicle lumen • cytoplasmic vesicle • neuronal dense core vesicle lumen • vesicle • neuronal dense core vesicle • vesicle lumen • dense core granule • secretory granule lumen • secretory granule • dense core granule lumen • secretory vesicle • Schaffer collateral - CA1 synapse • protein binding • binding • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular process • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • signal transduction • cell communication • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • response to oxygen-containing compound • cellular response to oxygen-containing compound • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to chemical stimulus • cellular response to alcohol • response to hormone • response to chemical • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular membrane-bounded organelle • non-motile cilium • 9+0 non-motile cilium • cilium • photoreceptor disc membrane • photoreceptor outer segment • photoreceptor cell cilium • organelle membrane • cytosol • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome • G-protein beta-subunit binding • fibroblast proliferation • molecular transducer activity • growth hormone secretagogue receptor activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • peptide hormone binding • hormone binding • identical protein binding • growth hormone-releasing hormone receptor activity • digestive system process • regulation of system process • regulation of gastric motility • regulation of digestive system process • digestion • gastric motility • regulation of multicellular organismal process • response to peptide hormone • cellular response to peptide hormone stimulus • cellular response to insulin-like growth factor stimulus • spermatogenesis • sexual reproduction • reproductive process • multicellular organismal reproductive process • developmental process involved in reproduction • male gamete generation • gamete generation • regulation of tumor necrosis factor production • negative regulation of biological process • negative regulation of tumor necrosis factor production • cytokine production • regulation of cytokine production • negative regulation of cellular process • negative regulation of macromolecule metabolic process • regulation of biosynthetic process • negative regulation of metabolic process • tumor necrosis factor superfamily cytokine production • negative regulation of cytokine production • regulation of macromolecule metabolic process • gene expression • macromolecule biosynthetic process • tumor necrosis factor production • regulation of gene expression • negative regulation of gene expression • regulation of tumor necrosis factor superfamily cytokine production • biosynthetic process • negative regulation of biosynthetic process • negative regulation of macromolecule biosynthetic process • negative regulation of tumor necrosis factor superfamily cytokine production • metabolic process • regulation of macromolecule biosynthetic process • macromolecule metabolic process • negative regulation of multicellular organismal process • regulation of metabolic process • interleukin-6 production • regulation of interleukin-6 production • negative regulation of interleukin-6 production • negative regulation of behavior • negative regulation of locomotion • locomotion involved in locomotory behavior • behavior • regulation of behavior • negative regulation of locomotion involved in locomotory behavior • locomotory behavior • regulation of locomotion • regulation of locomotion involved in locomotory behavior • locomotion • regulation of localization • regulation of hormone secretion • nitrogen compound transport • regulation of peptide secretion • transport • hormone secretion • localization • peptide secretion • regulation of secretion by cell • secretion by cell • signal release • regulation of biological quality • regulation of peptide hormone secretion • regulation of signaling • growth hormone secretion • regulation of transport • secretion • regulation of hormone levels • regulation of growth hormone secretion • regulation of peptide transport • export from cell • establishment of localization • regulation of secretion • peptide transport • peptide hormone secretion • regulation of cell communication • hormone transport • intestinal motility • positive regulation of small intestinal transit • positive regulation of biological process • positive regulation of digestive system process • positive regulation of multicellular organismal process • small intestinal transit • regulation of small intestinal transit • cell surface receptor signaling pathway • insulin-like growth factor receptor signaling pathway • cell surface receptor protein tyrosine kinase signaling pathway • enzyme-linked receptor protein signaling pathway • positive regulation of cell communication • positive regulation of signal transduction • regulation of signal transduction • positive regulation of response to stimulus • positive regulation of insulin-like growth factor receptor signaling pathway • regulation of insulin-like growth factor receptor signaling pathway • positive regulation of cellular process • regulation of response to stimulus • positive regulation of signaling • trans-synaptic signaling • modulation of chemical synaptic transmission • chemical synaptic transmission • regulation of trans-synaptic signaling • anterograde trans-synaptic signaling • postsynaptic modulation of chemical synaptic transmission • response to glucocorticoid • response to corticosteroid • response to steroid hormone • response to dexamethasone • positive regulation of cell population proliferation • endothelial cell proliferation • positive regulation of epithelial cell proliferation • regulation of vascular endothelial cell proliferation • regulation of endothelial cell proliferation • regulation of cell population proliferation • positive regulation of endothelial cell proliferation • regulation of epithelial cell proliferation • vascular endothelial cell proliferation • epithelial cell proliferation • positive regulation of vascular endothelial cell proliferation • response to growth hormone • response to thyroid hormone • cellular response to thyroid hormone stimulus • response to acid chemical • response to L-glutamate • response to amino acid • regulation of cellular component organization • cellular component organization • cellular component biogenesis • cellular component assembly • cell junction assembly • regulation of synapse structure or activity • regulation of synapse assembly • synapse organization • cellular component organization or biogenesis • nervous system development • regulation of cellular component biogenesis • regulation of cell junction assembly • regulation of synapse organization • cell junction organization • synapse assembly • response to gonadotropin • response to follicle-stimulating hormone • postsynapse organization • regulation of postsynapse organization • regulation of hindgut contraction • muscle contraction • muscle system process • regulation of muscle system process • hindgut contraction • smooth muscle contraction • regulation of smooth muscle contraction • regulation of muscle contraction • adult feeding behavior • adult behavior • feeding behavior • actin polymerization or depolymerization • organelle organization • actin cytoskeleton organization • actin filament organization • actin filament-based process • supramolecular fiber organization • cytoskeleton organization • positive regulation of smooth muscle contraction • intestine smooth muscle contraction • regulation of gastro-intestinal system smooth muscle contraction • positive regulation of small intestine smooth muscle contraction • regulation of small intestine smooth muscle contraction • small intestine smooth muscle contraction • gastro-intestinal system smooth muscle contraction • phasic smooth muscle contraction • positive regulation of gastro-intestinal system smooth muscle contraction • positive regulation of muscle contraction • leukocyte apoptotic process • regulation of programmed cell death • macrophage apoptotic process • negative regulation of leukocyte apoptotic process • myeloid cell apoptotic process • regulation of leukocyte apoptotic process • negative regulation of programmed cell death • regulation of apoptotic process • negative regulation of macrophage apoptotic process • cell death • negative regulation of apoptotic process • regulation of macrophage apoptotic process • inflammatory cell apoptotic process • negative regulation of myeloid cell apoptotic process • apoptotic process • regulation of myeloid cell apoptotic process • programmed cell death • response to nutrient levels • regulation of response to nutrient levels • negative regulation of response to food • negative regulation of response to nutrient levels • negative regulation of response to stimulus • negative regulation of appetite • regulation of response to food • response to food • regulation of appetite • oxoacid metabolic process • ketone metabolic process • regulation of lipid metabolic process • organic acid metabolic process • regulation of primary metabolic process • positive regulation of metabolic process • regulation of small molecule metabolic process • positive regulation of lipid metabolic process • small molecule metabolic process • positive regulation of fatty acid metabolic process • fatty acid metabolic process • carboxylic acid metabolic process • primary metabolic process • regulation of ketone metabolic process • regulation of fatty acid metabolic process • monocarboxylic acid metabolic process • positive regulation of small molecule metabolic process • lipid metabolic process • hormone-mediated signaling pathway • regulation of defense response • regulation of response to external stimulus • negative regulation of inflammatory response • defense response • response to external stimulus • regulation of inflammatory response • response to stress • negative regulation of response to external stimulus • regulation of response to stress • negative regulation of defense response • inflammatory response • interleukin-1 production • regulation of interleukin-1 beta production • negative regulation of interleukin-1 beta production • negative regulation of interleukin-1 production • regulation of interleukin-1 production • interleukin-1 beta production • biological process involved in interspecies interaction between organisms • response to other organism • cellular response to lipopolysaccharide • cellular response to molecule of bacterial origin • response to lipopolysaccharide • response to biotic stimulus • cellular response to biotic stimulus • response to bacterium • response to external biotic stimulus • response to molecule of bacterial origin • positive regulation of appetite • positive regulation of response to food • positive regulation of response to nutrient levels • negative regulation of protein transport • establishment of protein localization • negative regulation of transport • negative regulation of secretion • negative regulation of hormone secretion • negative regulation of secretion by cell • intracellular protein localization • negative regulation of peptide hormone secretion • establishment of protein localization to extracellular region • negative regulation of establishment of protein localization • protein secretion • regulation of protein secretion • negative regulation of protein secretion • regulation of protein localization • negative regulation of signaling • negative regulation of cell communication • protein localization to extracellular region • negative regulation of peptide secretion • negative regulation of protein localization • regulation of establishment of protein localization • regulation of protein transport • negative regulation of insulin secretion • protein transport • regulation of insulin secretion • macromolecule localization • insulin secretion • ghrelin secretion • cellular localization • protein localization to synapse • regulation of neurotransmitter receptor localization to postsynaptic specialization membrane • regulation of protein localization to synapse • neurotransmitter receptor localization to postsynaptic specialization membrane • regulation of protein localization to membrane • regulation of receptor localization to synapse • protein localization to postsynaptic specialization membrane • protein localization to cell periphery • protein localization to postsynaptic membrane • regulation of protein localization to cell periphery • localization within membrane • protein localization to membrane • protein-containing complex localization • regulation of postsynaptic membrane neurotransmitter receptor levels • regulation of cellular localization • protein localization to organelle • protein localization to postsynapse • protein localization to cell junction • receptor localization to synapse • multi-multicellular organism process • placenta development • maternal process involved in female pregnancy • tissue development • maternal placenta development • female pregnancy • multi-organism reproductive process • decidualization • learning or memory • cognition • regulation of multicellular organism growth • regulation of growth • regulation of developmental growth • regulation of developmental process • developmental growth • growth • positive regulation of multicellular organism growth • positive regulation of developmental process • multicellular organism growth • positive regulation of growth • positive regulation of developmental growth • regulation of sprouting angiogenesis • angiogenesis • regulation of vasculature development • tube morphogenesis • positive regulation of sprouting angiogenesis • regulation of anatomical structure morphogenesis • blood vessel development • regulation of multicellular organismal development • blood vessel morphogenesis • tube development • positive regulation of angiogenesis • sprouting angiogenesis • vasculature development • circulatory system development • anatomical structure morphogenesis • positive regulation of vasculature development • regulation of angiogenesis • anatomical structure formation involved in morphogenesis • regulation of eating behavior • positive regulation of feeding behavior • eating behavior • positive regulation of eating behavior • positive regulation of behavior • regulation of feeding behavior • response to insulin • cellular response to insulin stimulus • monoamine transport • negative regulation of amine transport • regulation of catecholamine secretion • organic hydroxy compound transport • catecholamine transport • negative regulation of norepinephrine secretion • norepinephrine transport • negative regulation of catecholamine secretion • organic cation transport • catecholamine secretion • amine transport • norepinephrine secretion • regulation of amine transport • regulation of norepinephrine secretion • transmission of nerve impulse • regulation of nervous system process • regulation of transmission of nerve impulse • response to estradiol • plasma membrane region • synaptic membrane • cell surface • membrane microdomain • membrane raft • mu-type opioid receptor binding • signaling receptor binding • G protein-coupled receptor binding • opioid receptor binding • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • peptide hormone receptor binding • corticotropin-releasing hormone receptor binding • corticotropin-releasing hormone receptor 1 binding • hormone receptor binding • neuropeptide receptor binding • G protein-coupled serotonin receptor binding • G-protein beta/gamma-subunit complex binding • G protein activity • molecular function regulator activity • cation binding • metal ion binding • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • heart process • regulation of heart contraction • circulatory system process • regulation of blood circulation • heart contraction • blood circulation • membrane docking • vesicle-mediated transport • organelle localization by membrane tethering • exocytosis • organelle localization • vesicle docking • exocytic process • vesicle docking involved in exocytosis • postsynaptic membrane • parallel fiber to Purkinje cell synapse • excitatory synapse • presynapse • presynaptic membrane • somatodendritic compartment • dendrite • dendritic tree • GABA-ergic synapse • cell body
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain • G protein-coupled receptor-like
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain • G protein-coupled receptor-like
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	K4Q
PDB Residues	L:L:?3
Environment Details	Open EMBL-EBI Page
Code	K4Q
Name	[(2~{S})-2-azanyl-3-oxidanylidene-propyl] octanoate
Synonyms
Identifier
Formula	C11 H21 N O3
Molecular Weight	215.289
SMILES
PubChem	155312307
Formal Charge	0
Total Atoms	36
Total Chiral Atoms	1
Total Bonds	35
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	L
Protein	Ghrelin
UniProt	Q9UBU3
Sequence	>7W2Z_nogp_Chain_L Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	R
Protein	Receptor
UniProt	Q92847
Sequence	>7W2Z_nogp_Chain_R L Q L F P A P L L A G V T A T C V A L F V V G I A G N L L T M L V V S R F R E L R T T T N L Y L S S M A F S D L L I F L C M P L D L V R L W Q Y R P W N F G D L L C K L F Q F V S E S C T Y A T V L T I T A L S V E R Y F A I C F P L R A K V V V T K G R V K L V I F V I W A V A F C S A G P I F V L V G V E H E N G T D P W D T N E C R P T E F A V R S G L L T V M V W V S S I F F F L P V F C L T V L Y S L I G R K L W R R R R G S L R D Q N H K Q T V K M L A V V V F A F I L C W L P F H V G R Y L F S K S F E P G S L E I A Q I S Q Y C N L V S F V L F Y L S A A I N P I L Y N I M S K K Y R V A V F R L L G F E Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	6KO5	A	Peptide	Ghrelin	Ghrelin	Homo sapiens	PubChem 57400002	-	-	3.3	2020-08-12	doi.org/10.1038/s41467-020-17554-1
	7F9Y	A	Peptide	Ghrelin	Ghrelin	Homo sapiens	Ghrelin	-	chim(NtGi1-Gs-CtGq)/β1/γ2	2.9	2021-08-18	doi.org/10.1038/s41467-021-25364-2
	7F9Y (No Gprot)	A	Peptide	Ghrelin	Ghrelin	Homo sapiens	Ghrelin	-		2.9	2021-08-18	doi.org/10.1038/s41467-021-25364-2
	7F9Z	A	Peptide	Ghrelin	Ghrelin	Homo sapiens	GHRP-6	-	chim(NtGi1-Gs-CtGq)/β1/γ2	3.2	2021-08-18	doi.org/10.1038/s41467-021-25364-2
	7F9Z (No Gprot)	A	Peptide	Ghrelin	Ghrelin	Homo sapiens	GHRP-6	-		3.2	2021-08-18	doi.org/10.1038/s41467-021-25364-2
	7NA7	A	Peptide	Ghrelin	Ghrelin	Homo sapiens	Ghrelin	-	Gi1/β1/γ2	2.7	2021-12-15	doi.org/10.1038/s41467-021-26735-5
	7NA7 (No Gprot)	A	Peptide	Ghrelin	Ghrelin	Homo sapiens	Ghrelin	-		2.7	2021-12-15	doi.org/10.1038/s41467-021-26735-5
	7NA8	A	Peptide	Ghrelin	Ghrelin	Homo sapiens	Ibutamoren	-	Gi1/β1/γ2	2.7	2021-12-15	doi.org/10.1038/s41467-021-26735-5
	7NA8 (No Gprot)	A	Peptide	Ghrelin	Ghrelin	Homo sapiens	Ibutamoren	-		2.7	2021-12-15	doi.org/10.1038/s41467-021-26735-5
	7F83	A	Peptide	Ghrelin	Ghrelin	Homo sapiens	PF-05190457	-	-	2.94	2022-01-19	doi.org/10.1038/s41467-022-27975-9
	7W2Z	A	Peptide	Ghrelin	Ghrelin	Homo sapiens	Ghrelin	-	Go/β1/γ2	2.8	2022-01-19	doi.org/10.1038/s41467-022-27975-9
	7W2Z (No Gprot)	A	Peptide	Ghrelin	Ghrelin	Homo sapiens	Ghrelin	-		2.8	2022-01-19	doi.org/10.1038/s41467-022-27975-9
	8JSR	A	Peptide	Ghrelin	Ghrelin	Homo sapiens	Anamorelin	-	chim(NtGi1-Gs-CtGq)/β1/γ2	2.9	2025-01-22	doi.org/10.1038/s41594-024-01481-6
	8JSR (No Gprot)	A	Peptide	Ghrelin	Ghrelin	Homo sapiens	Anamorelin	-		2.9	2025-01-22	doi.org/10.1038/s41594-024-01481-6
	9UY3	A	Peptide	Ghrelin	Ghrelin	Homo sapiens	Anamorelin	-	chim(NtGi1-Gs-CtGq)/β1/γ2	2.52	2025-07-02	doi.org/10.1038/s41401-025-01606-7
	9UY3 (No Gprot)	A	Peptide	Ghrelin	Ghrelin	Homo sapiens	Anamorelin	-		2.52	2025-07-02	doi.org/10.1038/s41401-025-01606-7
	9V2N	A	Peptide	Ghrelin	Ghrelin	Homo sapiens	Macimorelin	-	chim(NtGi1-Gs-CtGq)/β1/γ2	2.63	2025-07-02	doi.org/10.1038/s41401-025-01606-7
	9V2N (No Gprot)	A	Peptide	Ghrelin	Ghrelin	Homo sapiens	Macimorelin	-		2.63	2025-07-02	doi.org/10.1038/s41401-025-01606-7

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