psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:E26	R:R:F29	3.5	No	Yes	0	2	4
2	L:L:V303	R:R:C28	5.12	No	No	0	8	9
3	R:R:C274	R:R:F29	6.98	No	Yes	0	5	4
4	R:R:E277	R:R:F29	8.16	No	Yes	0	2	4
5	L:L:S316	R:R:F29	5.28	No	Yes	0	5	4
6	L:L:F314	R:R:E31	3.5	No	No	0	4	5
7	R:R:K38	R:R:N33	4.2	No	No	0	4	6
8	R:R:A34	R:R:N37	6.25	No	Yes	0	1	3
9	C:C:F276	R:R:N35	3.62	No	No	0	1	3
10	C:C:T279	R:R:N35	4.39	No	No	0	2	3
11	R:R:F36	R:R:F40	10.72	No	No	0	4	5
12	C:C:W283	R:R:F36	3.01	Yes	No	0	6	4
13	R:R:K282	R:R:N37	4.2	No	Yes	0	2	3
14	R:R:I286	R:R:N37	8.5	No	Yes	0	6	3
15	C:C:Q272	R:R:K38	12.2	No	No	0	2	4
16	C:C:F276	R:R:K38	3.72	No	No	0	1	4
17	C:C:I261	R:R:I39	2.94	Yes	No	0	5	5
18	C:C:W283	R:R:I39	15.27	Yes	No	0	6	5
19	R:R:F40	R:R:I44	7.54	No	Yes	0	5	5
20	R:R:L41	R:R:S285	3	No	No	0	6	5
21	R:R:A289	R:R:L41	4.73	No	No	0	4	6
22	R:R:A98	R:R:P42	3.74	No	No	0	5	5
23	C:C:I261	R:R:P42	3.39	Yes	No	0	5	5
24	C:C:P254	R:R:T43	5.25	No	No	0	9	4
25	C:C:I257	R:R:T43	6.08	No	No	0	6	4
26	C:C:W283	R:R:T43	8.49	Yes	No	0	6	4
27	R:R:I44	R:R:I48	2.94	Yes	Yes	15	5	7
28	R:R:I44	R:R:L290	2.85	Yes	No	0	5	7
29	R:R:F293	R:R:I44	3.77	Yes	Yes	15	5	5
30	R:R:W94	R:R:Y45	2.89	Yes	Yes	0	7	7
31	R:R:A289	R:R:Y45	5.34	No	Yes	0	4	7
32	R:R:F292	R:R:Y45	6.19	Yes	Yes	0	7	7
33	C:C:I257	R:R:S46	6.19	No	No	0	6	5
34	C:C:L253	R:R:I47	2.85	No	No	0	5	4
35	R:R:I48	R:R:L91	2.85	Yes	No	0	7	8
36	R:R:F293	R:R:I48	16.33	Yes	Yes	15	5	7
37	R:R:C295	R:R:I48	3.27	No	Yes	0	9	7
38	R:R:F49	R:R:L91	3.65	No	No	0	6	8
39	R:R:F49	R:R:P92	13	No	No	0	6	9
40	R:R:C296	R:R:T51	6.76	No	No	0	7	5
41	R:R:G52	R:R:V88	5.52	No	No	0	8	6
42	R:R:I53	R:R:V88	3.07	No	No	0	5	6
43	C:C:L216	R:R:V54	4.47	No	No	0	4	4
44	R:R:G55	R:R:P299	4.06	No	No	0	8	9
45	R:R:N56	R:R:S81	5.96	No	No	0	9	9
46	R:R:D84	R:R:N56	12.12	No	No	0	9	9
47	C:C:C220	R:R:L58	3.17	No	No	0	3	5
48	C:C:I223	R:R:L58	9.99	No	No	0	4	5
49	R:R:S81	R:R:V59	6.46	No	No	0	9	8
50	R:R:V59	R:R:Y302	6.31	No	Yes	0	8	9
51	R:R:I60	R:R:V82	3.07	No	No	0	7	5
52	R:R:M63	R:R:V62	3.04	Yes	No	0	6	7
53	R:R:K68	R:R:V62	3.04	No	No	0	6	7
54	R:R:D74	R:R:M63	4.16	Yes	Yes	11	8	6
55	R:R:M63	R:R:Y302	4.79	Yes	Yes	11	6	9
56	R:R:G64	R:R:L78	5.13	No	No	0	2	5
57	C:C:S224	R:R:Q66	4.33	No	Yes	0	4	4
58	C:C:S227	R:R:Q66	10.11	No	Yes	0	4	4
59	C:C:H228	R:R:Q66	4.95	No	Yes	0	5	4
60	R:R:K67	R:R:L69	4.23	No	No	0	6	6
61	C:C:S227	R:R:K68	3.06	No	No	0	4	6
62	R:R:D74	R:R:L69	5.43	Yes	No	0	8	6
63	R:R:K75	R:R:L69	7.05	No	No	0	6	6
64	R:R:D74	R:R:S71	4.42	Yes	No	0	8	7
65	R:R:D133	R:R:M72	8.32	No	No	7	8	6
66	R:R:M72	R:R:R148	6.2	No	Yes	7	6	6
67	R:R:A152	R:R:M72	3.22	No	No	0	3	6
68	R:R:D74	R:R:Y302	8.05	Yes	Yes	11	8	9
69	R:R:F129	R:R:Y76	6.19	No	Yes	0	5	7
70	R:R:I130	R:R:Y76	4.84	No	Yes	0	8	7
71	R:R:D133	R:R:Y76	10.34	No	Yes	0	8	7
72	R:R:V156	R:R:Y76	3.79	No	Yes	0	5	7
73	R:R:R77	R:R:T240	3.88	Yes	No	0	8	7
74	R:R:N298	R:R:R77	13.26	Yes	Yes	11	9	8
75	R:R:R77	R:R:Y302	29.84	Yes	Yes	11	8	9
76	R:R:H79	R:R:V156	4.15	No	No	0	9	5
77	R:R:H79	R:R:Y157	5.44	No	No	0	9	7
78	R:R:H79	R:R:W161	3.17	No	Yes	0	9	9
79	R:R:L80	R:R:N298	6.87	No	Yes	0	9	9
80	R:R:N298	R:R:S81	5.96	Yes	No	0	9	9
81	R:R:A83	R:R:N119	3.13	No	No	0	8	8
82	R:R:A83	R:R:S122	3.42	No	No	0	8	7
83	R:R:C295	R:R:D84	7.78	No	No	0	9	9
84	R:R:F87	R:R:L91	3.65	Yes	No	0	7	8
85	R:R:F87	R:R:Y116	8.25	Yes	Yes	3	7	6
86	R:R:F87	R:R:N119	12.08	Yes	No	0	7	8
87	R:R:F292	R:R:F87	16.08	Yes	Yes	3	7	7
88	R:R:C295	R:R:V88	3.42	No	No	0	9	6
89	R:R:F93	R:R:T90	6.49	Yes	Yes	3	6	6
90	R:R:T90	R:R:V112	4.76	Yes	Yes	3	6	5
91	R:R:I115	R:R:T90	6.08	No	Yes	0	5	6
92	R:R:F104	R:R:F93	10.72	Yes	Yes	0	7	6
93	R:R:F93	R:R:L108	4.87	Yes	No	0	6	5
94	R:R:F93	R:R:V112	3.93	Yes	Yes	3	6	5
95	R:R:D97	R:R:W94	3.35	No	Yes	0	5	7
96	R:R:V112	R:R:W94	6.13	Yes	Yes	0	5	7
97	R:R:H113	R:R:W94	7.41	Yes	Yes	0	6	7
98	R:R:F104	R:R:V96	6.55	Yes	No	0	7	5
99	R:R:D97	R:R:W102	8.93	No	Yes	0	5	9
100	C:C:I261	R:R:V99	4.61	Yes	No	0	5	4
101	R:R:N101	R:R:Y103	12.79	No	No	0	4	3
102	R:R:N101	R:R:R183	7.23	No	No	0	4	3
103	R:R:F104	R:R:W102	14.03	Yes	Yes	0	7	9
104	R:R:C109	R:R:W102	5.22	No	Yes	3	9	9
105	R:R:V112	R:R:W102	6.13	Yes	Yes	3	5	9
106	R:R:C186	R:R:W102	18.28	No	Yes	3	9	9
107	R:R:K110	R:R:N106	5.6	No	No	17	7	3
108	R:R:N106	R:R:N176	8.17	No	No	17	3	4
109	R:R:N106	R:R:V177	5.91	No	No	0	3	4
110	R:R:C109	R:R:H113	2.95	No	Yes	3	9	6
111	R:R:C109	R:R:C186	7.28	No	No	3	9	9
112	R:R:K110	R:R:N176	6.99	No	No	17	7	4
113	R:R:D171	R:R:H113	6.3	Yes	Yes	3	4	6
114	R:R:A175	R:R:H113	4.39	No	Yes	0	4	6
115	R:R:C186	R:R:H113	2.95	No	Yes	3	9	6
116	R:R:H113	R:R:R188	9.03	Yes	Yes	3	6	5
117	R:R:T168	R:R:V114	6.35	No	No	0	6	5
118	R:R:F172	R:R:V114	6.55	No	No	0	4	5
119	R:R:L120	R:R:Y116	4.69	No	Yes	0	7	6
120	R:R:R188	R:R:Y116	3.09	Yes	Yes	3	5	6
121	R:R:E288	R:R:Y116	5.61	Yes	Yes	3	5	6
122	R:R:F292	R:R:Y116	7.22	Yes	Yes	3	7	6
123	R:R:T117	R:R:T168	7.85	No	No	3	5	6
124	R:R:D171	R:R:T117	13.01	Yes	No	3	4	5
125	R:R:H203	R:R:L120	3.86	Yes	No	0	4	7
126	R:R:L120	R:R:W252	6.83	No	Yes	0	7	9
127	R:R:L167	R:R:Y121	7.03	No	Yes	13	5	7
128	R:R:Q202	R:R:Y121	5.64	No	Yes	13	3	7
129	R:R:H203	R:R:Y121	4.36	Yes	Yes	0	4	7
130	R:R:V206	R:R:Y121	12.62	No	Yes	13	4	7
131	R:R:S122	R:R:V160	3.23	No	Yes	16	7	7
132	R:R:S122	R:R:W161	11.12	No	Yes	16	7	9
133	R:R:F248	R:R:S123	6.61	Yes	No	3	9	9
134	R:R:H294	R:R:S123	4.18	No	No	3	9	9
135	R:R:G207	R:R:V124	3.68	No	No	0	5	7
136	R:R:P211	R:R:V124	3.53	No	No	0	9	7
137	R:R:L125	R:R:V160	4.47	No	Yes	0	5	7
138	R:R:I126	R:R:I130	2.94	No	No	0	7	8
139	R:R:I126	R:R:V160	7.68	No	Yes	0	7	7
140	R:R:I245	R:R:L127	2.85	No	No	0	7	8
141	R:R:F248	R:R:L127	8.53	Yes	No	0	9	8
142	R:R:F129	R:R:V160	5.24	No	Yes	0	5	7
143	R:R:I130	R:R:T241	3.04	No	No	0	8	7
144	R:R:I215	R:R:S131	6.19	No	No	0	7	9
145	R:R:C218	R:R:S131	3.44	Yes	No	0	6	9
146	R:R:D133	R:R:R148	10.72	No	Yes	7	8	6
147	R:R:A137	R:R:R134	4.15	No	Yes	7	8	9
148	R:R:R134	R:R:R148	3.2	Yes	Yes	7	9	6
149	R:R:L238	R:R:R134	3.64	Yes	Yes	7	5	9
150	R:R:V139	R:R:Y135	10.09	No	Yes	18	7	8
151	R:R:H140	R:R:Y135	3.27	Yes	Yes	18	6	8
152	R:R:C218	R:R:Y135	4.03	Yes	Yes	0	6	8
153	R:R:I221	R:R:Y135	4.84	No	Yes	0	4	8
154	R:R:A137	R:R:R148	6.91	No	Yes	7	8	6
155	R:R:I138	R:R:I222	7.36	No	Yes	0	8	8
156	R:R:H140	R:R:V139	6.92	Yes	No	18	6	7
157	R:R:K225	R:R:V139	3.04	No	No	0	4	7
158	R:R:N143	R:R:T142	5.85	No	No	0	5	5
159	R:R:E153	R:R:K149	6.75	No	No	0	7	6
160	R:R:K154	R:R:L150	7.05	No	No	0	3	4
161	R:R:L150	R:R:V155	2.98	No	No	0	4	2
162	R:R:L151	R:R:V155	2.98	No	No	0	4	2
163	R:R:V155	R:R:V158	3.21	No	No	0	2	4
164	R:R:G159	R:R:P163	4.06	No	No	0	3	4
165	R:R:V160	R:R:W161	7.36	Yes	Yes	16	7	9
166	R:R:I162	R:R:P163	3.39	No	No	0	4	4
167	R:R:L167	R:R:Q202	3.99	No	No	13	5	3
168	R:R:L167	R:R:V206	2.98	No	No	13	5	4
169	R:R:D171	R:R:T168	5.78	Yes	No	3	4	6
170	R:R:I169	R:R:P170	3.39	No	No	0	3	8
171	R:R:F172	R:R:I169	5.02	No	No	0	4	3
172	R:R:F199	R:R:P170	5.78	Yes	No	0	5	8
173	R:R:D171	R:R:R188	10.72	Yes	Yes	3	4	5
174	R:R:F174	R:R:I173	3.77	No	No	0	4	3
175	R:R:F174	R:R:Y190	6.19	No	Yes	3	4	4
176	R:R:F174	R:R:F199	4.29	No	Yes	3	4	5
177	R:R:I185	R:R:S178	4.64	Yes	No	0	3	1
178	L:L:M309	R:R:S178	6.13	No	No	0	7	1
179	R:R:E179	R:R:Y184	11.22	No	No	0	2	5
180	R:R:F189	R:R:I185	3.77	No	Yes	0	3	3
181	L:L:F314	R:R:I185	12.56	No	Yes	0	4	3
182	L:L:F312	R:R:D187	3.58	Yes	No	0	5	3
183	L:L:K313	R:R:D187	6.91	No	No	0	5	3
184	R:R:R188	R:R:Y190	9.26	Yes	Yes	3	5	4
185	L:L:F312	R:R:R188	17.1	Yes	Yes	3	5	5
186	R:R:W195	R:R:Y190	3.86	Yes	Yes	3	5	4
187	R:R:V196	R:R:Y190	5.05	No	Yes	0	4	4
188	R:R:F199	R:R:Y190	17.54	Yes	Yes	3	5	4
189	L:L:G311	R:R:Y190	2.9	No	Yes	0	9	4
190	L:L:F312	R:R:Y190	7.22	Yes	Yes	3	5	4
191	R:R:P191	R:R:W195	9.46	No	Yes	0	5	5
192	R:R:N192	R:R:W195	10.17	No	Yes	0	1	5
193	L:L:S310	R:R:D193	2.94	No	No	0	8	1
194	L:L:K317	R:R:D193	8.3	No	No	0	8	1
195	R:R:F199	R:R:W195	3.01	Yes	Yes	3	5	5
196	R:R:Q200	R:R:V196	2.87	Yes	No	0	5	4
197	R:R:L266	R:R:V196	2.98	No	No	0	3	4
198	R:R:S263	R:R:V197	4.85	No	No	0	5	3
199	R:R:L266	R:R:V197	2.98	No	No	0	3	3
200	R:R:L267	R:R:V197	4.47	No	No	0	1	3
201	R:R:D262	R:R:Q200	7.83	Yes	Yes	0	5	5
202	R:R:Q200	R:R:S263	5.78	Yes	No	0	5	5
203	L:L:F312	R:R:Q200	9.37	Yes	Yes	0	5	5
204	R:R:F201	R:R:S263	11.89	No	No	0	4	5
205	R:R:F201	R:R:F264	5.36	No	No	0	4	4
206	R:R:Q202	R:R:V206	2.87	No	No	13	3	4
207	R:R:H203	R:R:Y256	3.27	Yes	Yes	0	4	8
208	L:L:F312	R:R:H203	3.39	Yes	Yes	0	5	4
209	R:R:I204	R:R:I259	5.89	No	Yes	0	5	5
210	R:R:I209	R:R:M205	5.83	No	No	0	4	4
211	R:R:G207	R:R:Y256	2.9	No	Yes	0	5	8
212	R:R:I209	R:R:L208	2.85	No	No	0	4	8
213	R:R:L208	R:R:L253	4.15	No	No	0	8	5
214	R:R:L208	R:R:Y256	12.89	No	Yes	0	8	8
215	R:R:I215	R:R:I245	5.89	No	No	0	7	7
216	R:R:F249	R:R:I215	3.77	No	No	0	4	7
217	R:R:L216	S:S:V54	5.96	No	No	0	4	4
218	R:R:I222	R:R:Y219	6.04	Yes	Yes	7	8	8
219	R:R:L238	R:R:Y219	4.69	Yes	Yes	7	5	8
220	R:R:T241	R:R:Y219	4.99	No	Yes	0	7	8
221	R:R:V242	R:R:Y219	6.31	No	Yes	7	4	8
222	R:R:I245	R:R:Y219	3.63	No	Yes	0	7	8
223	R:R:I221	R:R:S224	3.1	No	No	0	4	4
224	R:R:I222	R:R:L238	5.71	Yes	Yes	7	8	5
225	R:R:I223	S:S:L58	4.28	No	No	0	4	5
226	R:R:K225	R:R:S224	3.06	No	No	0	4	4
227	R:R:S224	S:S:L61	4.5	No	No	0	4	4
228	R:R:S227	S:S:Q66	7.22	No	No	0	4	4
229	R:R:H228	S:S:Q66	7.42	No	No	0	5	4
230	R:R:H232	R:R:S229	9.76	No	No	0	4	5
231	R:R:K230	S:S:K68	5.75	No	No	0	5	6
232	R:R:H232	R:R:R235	7.9	No	No	0	4	5
233	R:R:K234	R:R:R235	7.43	No	No	0	7	5
234	R:R:K236	R:R:K239	2.87	No	No	0	8	6
235	R:R:L238	R:R:V242	2.98	Yes	No	7	5	4
236	R:R:I243	R:R:K239	2.91	No	No	0	5	6
237	R:R:I243	R:R:L301	4.28	No	No	0	5	7
238	R:R:A247	R:R:L297	4.73	No	No	0	6	6
239	R:R:F248	R:R:F249	5.36	Yes	No	0	9	4
240	R:R:F248	R:R:W252	10.02	Yes	Yes	3	9	9
241	R:R:F248	R:R:H294	10.18	Yes	No	3	9	9
242	R:R:W252	R:R:Y255	7.72	Yes	No	0	9	7
243	R:R:W252	R:R:Y256	3.86	Yes	Yes	0	9	8
244	R:R:A291	R:R:W252	5.19	No	Yes	0	8	9
245	R:R:F292	R:R:W252	3.01	Yes	Yes	3	7	9
246	R:R:H294	R:R:W252	12.7	No	Yes	3	9	9
247	R:R:L253	S:S:I47	2.85	No	No	0	5	4
248	R:R:L253	S:S:L50	4.15	No	No	0	5	5
249	R:R:P254	R:R:T287	3.5	No	No	0	9	6
250	R:R:P254	S:S:T43	5.25	No	No	0	9	4
251	R:R:I259	R:R:Y255	10.88	Yes	No	0	5	7
252	R:R:E288	R:R:Y255	14.59	Yes	No	0	5	7
253	R:R:I259	R:R:Y256	3.63	Yes	Yes	0	5	8
254	R:R:I257	S:S:T43	4.56	No	No	0	6	4
255	R:R:I257	S:S:S46	6.19	No	No	0	6	5
256	R:R:I259	R:R:I284	5.89	Yes	No	0	5	4
257	R:R:I261	S:S:I39	2.94	No	Yes	0	5	5
258	R:R:I261	S:S:P42	3.39	No	No	19	5	5
259	R:R:I261	S:S:V99	4.61	No	No	19	5	4
260	R:R:D262	R:R:V280	4.38	Yes	Yes	8	5	5
261	R:R:D262	R:R:H281	6.3	Yes	No	8	5	4
262	L:L:H315	R:R:D262	10.08	No	Yes	8	5	5
263	R:R:I265	R:R:I270	7.36	Yes	Yes	0	3	5
264	R:R:F276	R:R:I265	6.28	Yes	Yes	8	1	3
265	R:R:E277	R:R:I265	5.47	No	Yes	0	2	3
266	R:R:I265	R:R:V280	3.07	Yes	Yes	8	3	5
267	L:L:H315	R:R:L266	9	No	No	0	5	3
268	R:R:I269	R:R:L267	4.28	No	No	0	1	1
269	L:L:K317	R:R:E268	6.75	No	No	0	8	2
270	R:R:I269	R:R:I270	2.94	No	Yes	0	1	5
271	R:R:I270	R:R:Q272	4.12	Yes	No	0	5	2
272	R:R:I270	S:S:V99	3.07	Yes	No	0	5	4
273	R:R:Q272	S:S:K38	6.78	No	Yes	0	2	4
274	R:R:F276	R:R:V280	5.24	Yes	Yes	8	1	5
275	R:R:F276	S:S:N35	7.25	Yes	Yes	8	1	3
276	R:R:F276	S:S:K38	3.72	Yes	Yes	8	1	4
277	R:R:E277	R:R:H281	7.39	No	No	0	2	4
278	R:R:T279	S:S:I39	3.04	No	Yes	0	2	5
279	R:R:I284	R:R:V280	3.07	No	Yes	0	4	5
280	L:L:H315	R:R:H281	13.14	No	No	8	5	4
281	R:R:T287	R:R:W283	10.92	No	Yes	0	6	6
282	R:R:W283	S:S:I39	12.92	Yes	Yes	0	6	5
283	R:R:W283	S:S:T43	9.7	Yes	No	0	6	4
284	R:R:E288	R:R:F292	5.83	Yes	Yes	3	5	7
285	L:L:K313	R:R:E288	8.1	No	Yes	0	5	5
286	R:R:C296	R:R:I300	4.91	No	No	0	7	6
287	R:R:N298	R:R:P299	3.26	Yes	No	0	9	9
288	R:R:N298	R:R:Y302	9.3	Yes	Yes	11	9	9
289	S:S:E26	S:S:K25	9.45	No	No	0	2	4
290	S:S:E277	S:S:P27	4.72	No	No	0	2	5
291	S:S:H281	S:S:R30	13.54	No	No	0	4	5
292	S:S:E32	S:S:N35	7.89	No	Yes	0	4	3
293	S:S:N33	S:S:N37	10.9	No	No	0	6	3
294	S:S:K38	S:S:N33	5.6	Yes	No	0	4	6
295	S:S:A34	S:S:K282	3.21	No	No	0	1	2
296	S:S:K38	S:S:N35	6.99	Yes	Yes	8	4	3
297	S:S:K282	S:S:N37	4.2	No	No	0	2	3
298	S:S:I286	S:S:N37	9.91	No	No	0	6	3
299	S:S:F40	S:S:I44	8.79	No	No	0	5	5
300	S:S:L41	S:S:Y45	7.03	No	Yes	0	6	7
301	S:S:A98	S:S:L41	3.15	No	No	0	5	6
302	S:S:L41	S:S:S285	4.5	No	No	0	6	5
303	S:S:A98	S:S:P42	5.61	No	No	0	5	5
304	S:S:P42	S:S:V99	3.53	No	No	19	5	4
305	S:S:A289	S:S:I44	3.25	No	No	0	4	5
306	S:S:W94	S:S:Y45	2.89	Yes	Yes	0	7	7
307	S:S:A289	S:S:Y45	4	No	Yes	0	4	7
308	S:S:F292	S:S:Y45	6.19	Yes	Yes	0	7	7
309	S:S:I48	S:S:L91	2.85	No	Yes	0	7	8
310	S:S:F293	S:S:I48	16.33	No	No	0	5	7
311	S:S:F49	S:S:L91	3.65	No	Yes	0	6	8
312	S:S:F49	S:S:P92	7.22	No	No	0	6	9
313	S:S:C296	S:S:T51	5.07	No	No	0	7	5
314	S:S:G52	S:S:V88	3.68	No	No	0	8	6
315	S:S:I53	S:S:L85	2.85	No	No	0	5	7
316	S:S:G55	S:S:V54	3.68	No	No	0	8	4
317	S:S:G55	S:S:P299	4.06	No	Yes	0	8	9
318	S:S:N56	S:S:S81	5.96	Yes	Yes	0	9	9
319	S:S:D84	S:S:N56	4.04	Yes	Yes	0	9	9
320	S:S:L85	S:S:N56	5.49	No	Yes	0	7	9
321	S:S:N56	S:S:P299	3.26	Yes	Yes	0	9	9
322	S:S:S81	S:S:V59	8.08	Yes	No	0	9	8
323	S:S:P299	S:S:V59	3.53	Yes	No	0	9	8
324	S:S:I60	S:S:L78	2.85	No	No	0	7	5
325	S:S:M63	S:S:V62	4.56	No	No	0	6	7
326	S:S:K68	S:S:V62	3.04	No	No	0	6	7
327	S:S:M63	S:S:Y302	11.97	No	No	0	6	9
328	S:S:K75	S:S:L69	4.23	No	No	0	6	6
329	S:S:D74	S:S:S71	8.83	No	No	0	8	7
330	S:S:K75	S:S:M72	2.88	No	Yes	0	6	6
331	S:S:D133	S:S:M72	6.93	No	Yes	9	8	6
332	S:S:M72	S:S:R148	6.2	Yes	Yes	9	6	6
333	S:S:A152	S:S:M72	3.22	No	Yes	0	3	6
334	S:S:D74	S:S:Y302	5.75	No	No	0	8	9
335	S:S:E153	S:S:K75	5.4	No	No	0	7	6
336	S:S:F129	S:S:Y76	3.09	Yes	Yes	9	5	7
337	S:S:I130	S:S:Y76	4.84	No	Yes	0	8	7
338	S:S:D133	S:S:Y76	11.49	No	Yes	9	8	7
339	S:S:L151	S:S:Y76	3.52	No	Yes	9	4	7
340	S:S:V156	S:S:Y76	3.79	No	Yes	9	5	7
341	S:S:N298	S:S:R77	6.03	Yes	Yes	0	9	8
342	S:S:R77	S:S:Y302	27.78	Yes	No	0	8	9
343	S:S:H79	S:S:Y157	6.53	No	No	0	9	7
344	S:S:H79	S:S:W161	3.17	No	Yes	0	9	9
345	S:S:D84	S:S:L80	4.07	Yes	No	0	9	9
346	S:S:I126	S:S:L80	4.28	No	No	0	7	9
347	S:S:L80	S:S:N298	4.12	No	Yes	0	9	9
348	S:S:N298	S:S:S81	4.47	Yes	Yes	0	9	9
349	S:S:A83	S:S:S122	3.42	No	Yes	0	8	7
350	S:S:D84	S:S:N119	6.73	Yes	No	1	9	8
351	S:S:D84	S:S:H294	5.04	Yes	Yes	1	9	9
352	S:S:C295	S:S:D84	12.45	No	Yes	1	9	9
353	S:S:I115	S:S:L86	5.71	No	No	0	5	7
354	S:S:F87	S:S:L91	3.65	Yes	Yes	1	7	8
355	S:S:F87	S:S:W94	3.01	Yes	Yes	1	7	7
356	S:S:F87	S:S:Y116	8.25	Yes	Yes	1	7	6
357	S:S:F87	S:S:N119	13.29	Yes	No	1	7	8
358	S:S:F292	S:S:F87	15	Yes	Yes	1	7	7
359	S:S:C295	S:S:V88	3.42	No	No	0	9	6
360	S:S:F93	S:S:T90	5.19	Yes	Yes	1	6	6
361	S:S:T90	S:S:V112	4.76	Yes	Yes	1	6	5
362	S:S:I115	S:S:T90	6.08	No	Yes	0	5	6
363	S:S:L91	S:S:W94	3.42	Yes	Yes	1	8	7
364	S:S:F93	S:S:W102	3.01	Yes	Yes	1	6	9
365	S:S:F104	S:S:F93	13.93	No	Yes	1	7	6
366	S:S:F93	S:S:L108	3.65	Yes	No	0	6	5
367	S:S:F93	S:S:V112	5.24	Yes	Yes	1	6	5
368	S:S:V112	S:S:W94	4.9	Yes	Yes	1	5	7
369	S:S:H113	S:S:W94	6.35	No	Yes	0	6	7
370	S:S:W94	S:S:Y116	2.89	Yes	Yes	1	7	6
371	S:S:F104	S:S:V96	6.55	No	No	0	7	5
372	S:S:D97	S:S:W102	7.82	No	Yes	0	5	9
373	S:S:I185	S:S:N101	4.25	No	No	0	3	4
374	S:S:F104	S:S:W102	13.03	No	Yes	1	7	9
375	S:S:C109	S:S:W102	3.92	No	Yes	1	9	9
376	S:S:V112	S:S:W102	4.9	Yes	Yes	1	5	9
377	S:S:C186	S:S:W102	16.98	No	Yes	1	9	9
378	S:S:N106	S:S:N176	10.9	No	No	0	3	4
379	S:S:N106	S:S:V177	4.43	No	No	0	3	4
380	S:S:C109	S:S:V177	3.42	No	No	0	9	4
381	S:S:C109	S:S:C186	7.28	No	No	1	9	9
382	S:S:K110	S:S:N176	4.2	No	No	0	7	4
383	S:S:D171	S:S:H113	7.56	Yes	No	0	4	6
384	S:S:C186	S:S:H113	2.95	No	No	0	9	6
385	S:S:T168	S:S:V114	3.17	Yes	No	21	6	5
386	S:S:D171	S:S:V114	5.84	Yes	No	0	4	5
387	S:S:F172	S:S:V114	11.8	No	No	21	4	5
388	S:S:L120	S:S:Y116	4.69	No	Yes	0	7	6
389	S:S:E288	S:S:Y116	4.49	No	Yes	1	5	6
390	S:S:F292	S:S:Y116	5.16	Yes	Yes	1	7	6
391	S:S:T117	S:S:T168	3.14	No	Yes	0	5	6
392	S:S:D171	S:S:T117	7.23	Yes	No	0	4	5
393	S:S:T168	S:S:V118	3.17	Yes	No	0	6	5
394	S:S:H294	S:S:N119	5.1	Yes	No	1	9	8
395	S:S:H203	S:S:L120	9	Yes	No	0	4	7
396	S:S:L120	S:S:W252	4.56	No	Yes	0	7	9
397	S:S:L167	S:S:Y121	9.38	No	Yes	0	5	7
398	S:S:Q202	S:S:Y121	7.89	No	Yes	1	3	7
399	S:S:H203	S:S:Y121	5.44	Yes	Yes	1	4	7
400	S:S:V206	S:S:Y121	5.05	No	Yes	1	4	7
401	S:S:S122	S:S:V160	3.23	Yes	Yes	20	7	7
402	S:S:S122	S:S:W161	11.12	Yes	Yes	20	7	9
403	S:S:F248	S:S:S123	6.61	Yes	No	1	9	9
404	S:S:H294	S:S:S123	4.18	Yes	No	1	9	9
405	S:S:P211	S:S:V124	3.53	No	No	0	9	7
406	S:S:F248	S:S:V124	5.24	Yes	No	0	9	7
407	S:S:L125	S:S:V160	2.98	No	Yes	0	5	7
408	S:S:L125	S:S:P163	3.28	No	No	0	5	4
409	S:S:I126	S:S:I130	2.94	No	No	0	7	8
410	S:S:I126	S:S:V160	9.22	No	Yes	0	7	7
411	S:S:I245	S:S:L127	5.71	No	No	0	7	8
412	S:S:F248	S:S:L127	6.09	Yes	No	0	9	8
413	S:S:A128	S:S:I215	3.25	No	No	0	7	7
414	S:S:F129	S:S:L151	4.87	Yes	No	9	5	4
415	S:S:F129	S:S:V156	3.93	Yes	No	9	5	5
416	S:S:F129	S:S:G159	3.01	Yes	No	0	5	3
417	S:S:I215	S:S:S131	9.29	No	Yes	6	7	9
418	S:S:C218	S:S:S131	5.16	No	Yes	0	6	9
419	S:S:S131	S:S:Y219	6.36	Yes	Yes	6	9	8
420	S:S:I245	S:S:S131	3.1	No	Yes	6	7	9
421	S:S:D133	S:S:R148	13.1	No	Yes	9	8	6
422	S:S:R134	S:S:T241	3.88	No	No	0	9	7
423	S:S:V139	S:S:Y135	10.09	No	Yes	6	7	8
424	S:S:H140	S:S:Y135	6.53	Yes	Yes	6	6	8
425	S:S:C218	S:S:Y135	4.03	No	Yes	0	6	8
426	S:S:I221	S:S:Y135	8.46	No	Yes	0	4	8
427	S:S:I222	S:S:Y135	3.63	Yes	Yes	6	8	8
428	S:S:A137	S:S:R148	6.91	No	Yes	0	8	6
429	S:S:I138	S:S:K234	2.91	No	No	0	8	7
430	S:S:H140	S:S:V139	8.3	Yes	No	6	6	7
431	S:S:K225	S:S:V139	3.04	No	No	0	4	7
432	S:S:P147	S:S:R146	2.88	No	No	0	4	5
433	S:S:I162	S:S:V158	6.14	No	No	0	4	4
434	S:S:V160	S:S:W161	6.13	Yes	Yes	20	7	9
435	S:S:I162	S:S:P163	3.39	No	No	0	4	4
436	S:S:I162	S:S:L166	2.85	No	No	0	4	4
437	S:S:F172	S:S:T168	3.89	No	Yes	21	4	6
438	S:S:I169	S:S:P170	3.39	No	No	0	3	8
439	S:S:P170	S:S:R188	2.88	No	Yes	0	8	5
440	S:S:F199	S:S:P170	7.22	No	No	0	5	8
441	S:S:D171	S:S:R188	13.1	Yes	Yes	0	4	5
442	S:S:F174	S:S:I173	10.05	No	No	0	4	3
443	S:S:F174	S:S:Y190	8.25	No	Yes	0	4	4
444	S:S:F174	S:S:W195	4.01	No	No	0	4	5
445	S:S:F189	S:S:S178	3.96	No	No	0	3	1
446	S:S:E179	S:S:Y184	10.1	No	No	0	2	5
447	S:S:A180	S:S:R183	8.3	No	No	0	1	3
448	S:S:D181	S:S:R183	14.29	No	No	0	2	3
449	S:S:R188	S:S:Y190	17.49	Yes	Yes	0	5	4
450	S:S:V196	S:S:Y190	5.05	No	Yes	0	4	4
451	S:S:F199	S:S:Y190	6.19	No	Yes	0	5	4
452	S:S:N192	S:S:P191	4.89	Yes	No	0	1	5
453	S:S:N192	S:S:W195	7.91	Yes	No	0	1	5
454	S:S:F199	S:S:W195	5.01	No	No	0	5	5
455	S:S:S263	S:S:V197	4.85	No	No	0	5	3
456	S:S:L266	S:S:V197	2.98	No	No	0	3	3
457	S:S:L267	S:S:V197	2.98	No	No	0	1	3
458	S:S:Q200	S:S:S263	4.33	No	No	0	5	5
459	S:S:F201	S:S:S263	11.89	No	No	0	4	5
460	S:S:F201	S:S:F264	3.22	No	No	0	4	4
461	S:S:Q202	S:S:V206	4.3	No	No	1	3	4
462	S:S:H203	S:S:Y255	5.44	Yes	Yes	1	4	7
463	S:S:H203	S:S:Y256	10.89	Yes	Yes	1	4	8
464	S:S:H203	S:S:I259	3.98	Yes	Yes	1	4	5
465	S:S:I204	S:S:Y256	3.63	No	Yes	1	5	8
466	S:S:I204	S:S:I259	5.89	No	Yes	1	5	5
467	S:S:I209	S:S:M205	4.37	No	No	0	4	4
468	S:S:G207	S:S:Y256	2.9	No	Yes	0	5	8
469	S:S:L208	S:S:Y256	11.72	No	Yes	0	8	8
470	S:S:I215	S:S:I245	2.94	No	No	6	7	7
471	P:P:V54	S:S:L216	5.96	No	No	0	4	4
472	S:S:I222	S:S:Y219	7.25	Yes	Yes	6	8	8
473	S:S:L238	S:S:Y219	8.21	No	Yes	6	5	8
474	S:S:T241	S:S:Y219	3.75	No	Yes	0	7	8
475	S:S:V242	S:S:Y219	7.57	No	Yes	6	4	8
476	S:S:I222	S:S:L238	2.85	Yes	No	6	8	5
477	P:P:L58	S:S:I223	11.42	No	No	0	5	4
478	P:P:Q66	S:S:S224	2.89	No	No	0	4	4
479	P:P:Q66	S:S:S227	8.66	No	No	0	4	4
480	P:P:Q66	S:S:H228	8.65	No	No	0	4	5
481	S:S:H232	S:S:K234	10.48	No	No	0	4	7
482	S:S:K236	S:S:Q233	9.49	No	No	0	8	5
483	S:S:L238	S:S:V242	2.98	No	No	6	5	4
484	S:S:I243	S:S:L301	5.71	No	No	0	5	7
485	S:S:A247	S:S:L297	4.73	No	No	0	6	6
486	S:S:F248	S:S:F249	5.36	Yes	No	0	9	4
487	S:S:F248	S:S:W252	10.02	Yes	Yes	1	9	9
488	S:S:F248	S:S:H294	9.05	Yes	Yes	1	9	9
489	S:S:W252	S:S:Y255	7.72	Yes	Yes	1	9	7
490	S:S:W252	S:S:Y256	2.89	Yes	Yes	1	9	8
491	S:S:A291	S:S:W252	5.19	No	Yes	0	8	9
492	S:S:F292	S:S:W252	4.01	Yes	Yes	1	7	9
493	S:S:H294	S:S:W252	11.64	Yes	Yes	1	9	9
494	P:P:I47	S:S:L253	2.85	No	No	0	4	5
495	S:S:P254	S:S:T287	3.5	No	No	0	9	6
496	P:P:T43	S:S:P254	3.5	No	No	0	4	9
497	S:S:Y255	S:S:Y256	3.97	Yes	Yes	1	7	8
498	S:S:I259	S:S:Y255	10.88	Yes	Yes	1	5	7
499	S:S:E288	S:S:Y255	11.22	No	Yes	1	5	7
500	S:S:I259	S:S:Y256	3.63	Yes	Yes	1	5	8
501	P:P:T43	S:S:I257	4.56	No	No	0	4	6
502	P:P:S46	S:S:I257	6.19	No	No	0	5	6
503	S:S:G258	S:S:I284	3.53	No	Yes	0	4	4
504	S:S:I259	S:S:I284	4.42	Yes	Yes	1	5	4
505	S:S:I261	S:S:V280	3.07	Yes	Yes	1	5	5
506	P:P:I39	S:S:I261	2.94	Yes	Yes	1	5	5
507	P:P:P42	S:S:I261	3.39	No	Yes	1	5	5
508	P:P:V99	S:S:I261	3.07	No	Yes	1	4	5
509	S:S:D262	S:S:V280	4.38	No	Yes	1	5	5
510	S:S:D262	S:S:H281	8.82	No	No	0	5	4
511	S:S:D262	S:S:I284	5.6	No	Yes	1	5	4
512	S:S:F264	S:S:I269	6.28	No	No	0	4	1
513	S:S:I265	S:S:I270	2.94	No	No	0	3	5
514	S:S:I269	S:S:L267	2.85	No	No	0	1	1
515	S:S:I270	S:S:Q272	8.23	No	No	0	5	2
516	P:P:V99	S:S:I270	3.07	No	No	0	4	5
517	P:P:K38	S:S:Q272	5.42	No	No	0	4	2
518	P:P:N35	S:S:E275	7.89	No	No	0	3	3
519	S:S:F276	S:S:V280	5.24	No	Yes	0	1	5
520	P:P:K38	S:S:F276	3.72	No	No	0	4	1
521	P:P:N35	S:S:T279	11.7	No	No	0	3	2
522	S:S:I284	S:S:V280	3.07	Yes	Yes	1	4	5
523	P:P:I39	S:S:V280	3.07	Yes	Yes	1	5	5
524	S:S:T287	S:S:W283	7.28	No	Yes	0	6	6
525	P:P:F36	S:S:W283	4.01	No	Yes	1	4	6
526	P:P:I39	S:S:W283	11.74	Yes	Yes	1	5	6
527	P:P:T43	S:S:W283	8.49	No	Yes	0	4	6
528	S:S:E288	S:S:F292	5.83	No	Yes	1	5	7
529	S:S:C296	S:S:F293	4.19	No	No	0	7	5
530	S:S:C295	S:S:H294	7.37	No	Yes	1	9	9
531	S:S:N298	S:S:P299	4.89	Yes	Yes	0	9	9
532	S:S:F304	S:S:I300	3.77	No	No	0	6	6
533	C:C:E26	C:C:P27	3.14	No	No	0	2	5
534	C:C:C28	C:C:E26	4.56	No	No	0	9	2
535	C:C:C274	C:C:F29	8.38	No	No	0	5	4
536	C:C:E31	C:C:E32	5.07	No	No	0	5	4
537	C:C:E31	C:C:N278	9.2	No	No	0	5	3
538	C:C:N35	P:P:E275	6.57	No	No	0	3	3
539	C:C:N35	P:P:F276	7.25	No	Yes	0	3	1
540	C:C:N35	P:P:T279	7.31	No	No	0	3	2
541	C:C:F36	C:C:I39	3.77	No	No	10	4	5
542	C:C:F36	P:P:W283	3.01	No	Yes	10	4	6
543	C:C:K282	C:C:N37	8.39	No	Yes	0	2	3
544	C:C:I286	C:C:N37	8.5	No	Yes	0	6	3
545	C:C:I39	P:P:I261	4.42	No	Yes	10	5	5
546	C:C:I39	P:P:W283	11.74	No	Yes	10	5	6
547	C:C:F40	C:C:I44	7.54	No	No	0	5	5
548	C:C:L41	C:C:Y45	5.86	No	Yes	0	6	7
549	C:C:A98	C:C:L41	3.15	No	No	0	5	6
550	C:C:A98	C:C:P42	3.74	No	No	0	5	5
551	C:C:P42	C:C:V99	3.53	No	No	10	5	4
552	C:C:P42	P:P:I261	3.39	No	Yes	10	5	5
553	C:C:T43	P:P:P254	3.5	No	No	0	4	9
554	C:C:T43	P:P:I257	4.56	No	No	0	4	6
555	C:C:T43	P:P:W283	7.28	No	Yes	0	4	6
556	C:C:A289	C:C:I44	3.25	No	No	0	4	5
557	C:C:I44	C:C:L290	2.85	No	No	0	5	7
558	C:C:A289	C:C:Y45	4	No	Yes	0	4	7
559	C:C:F292	C:C:Y45	7.22	Yes	Yes	0	7	7
560	C:C:S46	P:P:L253	3	No	No	0	5	5
561	C:C:S46	P:P:I257	6.19	No	No	0	5	6
562	C:C:I47	P:P:L253	2.85	No	No	0	4	5
563	C:C:I48	C:C:L91	2.85	No	Yes	0	7	8
564	C:C:F293	C:C:I48	11.3	No	No	0	5	7
565	C:C:F49	C:C:L50	3.65	Yes	No	0	6	5
566	C:C:F49	C:C:I53	3.77	Yes	No	0	6	5
567	C:C:F49	C:C:L91	3.65	Yes	Yes	0	6	8
568	C:C:F49	C:C:P92	7.22	Yes	No	0	6	9
569	C:C:C296	C:C:T51	6.76	No	No	0	7	5
570	C:C:G52	C:C:V88	3.68	No	No	0	8	6
571	C:C:I53	C:C:V88	4.61	No	No	0	5	6
572	C:C:G55	C:C:V54	3.68	No	No	0	8	4
573	C:C:V54	P:P:L216	5.96	No	No	0	4	4
574	C:C:G55	C:C:P299	4.06	No	No	0	8	9
575	C:C:N56	C:C:S81	5.96	Yes	No	0	9	9
576	C:C:D84	C:C:N56	4.04	Yes	Yes	0	9	9
577	C:C:L85	C:C:N56	5.49	No	Yes	0	7	9
578	C:C:N56	C:C:P299	4.89	Yes	No	0	9	9
579	C:C:L58	P:P:I223	11.42	No	No	0	5	4
580	C:C:S81	C:C:V59	8.08	No	No	0	9	8
581	C:C:V59	C:C:Y302	3.79	No	Yes	0	8	9
582	C:C:I60	C:C:V82	3.07	No	No	0	7	5
583	C:C:I60	C:C:L85	2.85	No	No	0	7	7
584	C:C:L61	P:P:S224	4.5	No	No	0	4	4
585	C:C:M63	C:C:V62	4.56	No	Yes	22	6	7
586	C:C:K68	C:C:V62	4.55	No	Yes	22	6	7
587	C:C:K68	C:C:M63	4.32	No	No	22	6	6
588	C:C:M63	C:C:Y302	7.18	No	Yes	0	6	9
589	C:C:G64	C:C:L78	3.42	No	No	0	2	5
590	C:C:Q66	P:P:S224	4.33	No	No	0	4	4
591	C:C:Q66	P:P:S227	8.66	No	No	0	4	4
592	C:C:Q66	P:P:H228	4.95	No	No	0	4	5
593	C:C:K67	C:C:L69	4.23	No	No	0	6	6
594	C:C:K68	C:C:R70	4.95	No	No	0	6	6
595	C:C:K75	C:C:L69	5.64	No	No	0	6	6
596	C:C:D74	C:C:S71	2.94	No	No	0	8	7
597	C:C:K75	C:C:M72	5.76	No	Yes	0	6	6
598	C:C:M72	C:C:R148	4.96	Yes	No	0	6	6
599	C:C:A152	C:C:M72	3.22	No	Yes	0	3	6
600	C:C:R77	C:C:T73	3.88	Yes	No	0	8	7
601	C:C:D74	C:C:Y302	8.05	No	Yes	0	8	9
602	C:C:F129	C:C:Y76	6.19	No	Yes	23	5	7
603	C:C:I130	C:C:Y76	4.84	No	Yes	0	8	7
604	C:C:D133	C:C:Y76	6.9	No	Yes	0	8	7
605	C:C:L151	C:C:Y76	3.52	No	Yes	23	4	7
606	C:C:A152	C:C:Y76	5.34	No	Yes	0	3	7
607	C:C:R77	C:C:T240	5.17	Yes	No	0	8	7
608	C:C:L244	C:C:R77	3.64	No	Yes	0	7	8
609	C:C:N298	C:C:R77	9.64	Yes	Yes	0	9	8
610	C:C:L301	C:C:R77	3.64	No	Yes	0	7	8
611	C:C:R77	C:C:Y302	16.46	Yes	Yes	0	8	9
612	C:C:H79	C:C:Y157	4.36	No	No	0	9	7
613	C:C:H79	C:C:W161	3.17	No	Yes	0	9	9
614	C:C:D84	C:C:L80	4.07	Yes	Yes	0	9	9
615	C:C:I126	C:C:L80	4.28	Yes	Yes	0	7	9
616	C:C:L127	C:C:L80	4.15	No	Yes	0	8	9
617	C:C:L80	C:C:N298	4.12	Yes	Yes	0	9	9
618	C:C:N298	C:C:S81	4.47	Yes	No	0	9	9
619	C:C:A83	C:C:S122	3.42	No	Yes	12	8	7
620	C:C:A83	C:C:W161	3.89	No	Yes	12	8	9
621	C:C:D84	C:C:N119	4.04	Yes	No	2	9	8
622	C:C:D84	C:C:H294	6.3	Yes	Yes	2	9	9
623	C:C:C295	C:C:D84	10.89	No	Yes	2	9	9
624	C:C:F87	C:C:L91	3.65	Yes	Yes	2	7	8
625	C:C:F87	C:C:W94	3.01	Yes	Yes	2	7	7
626	C:C:F87	C:C:Y116	7.22	Yes	Yes	2	7	6
627	C:C:F87	C:C:N119	13.29	Yes	No	2	7	8
628	C:C:F292	C:C:F87	13.93	Yes	Yes	2	7	7
629	C:C:C295	C:C:V88	3.42	No	No	0	9	6
630	C:C:T90	C:C:V112	3.17	No	Yes	0	6	5
631	C:C:I115	C:C:T90	9.12	No	No	0	5	6
632	C:C:L91	C:C:W94	3.42	Yes	Yes	2	8	7
633	C:C:F93	C:C:W102	4.01	Yes	Yes	2	6	9
634	C:C:F104	C:C:F93	9.65	Yes	Yes	2	7	6
635	C:C:F93	C:C:L108	7.31	Yes	No	2	6	5
636	C:C:F93	C:C:V112	3.93	Yes	Yes	2	6	5
637	C:C:D97	C:C:W94	5.58	No	Yes	0	5	7
638	C:C:V112	C:C:W94	7.36	Yes	Yes	2	5	7
639	C:C:H113	C:C:W94	7.41	Yes	Yes	2	6	7
640	C:C:F104	C:C:V96	6.55	Yes	No	0	7	5
641	C:C:D97	C:C:W102	7.82	No	Yes	0	5	9
642	C:C:V99	P:P:I261	4.61	No	Yes	10	4	5
643	C:C:N101	C:C:R183	6.03	No	No	0	4	3
644	C:C:F104	C:C:W102	17.04	Yes	Yes	2	7	9
645	C:C:C109	C:C:W102	5.22	No	Yes	2	9	9
646	C:C:V112	C:C:W102	4.9	Yes	Yes	2	5	9
647	C:C:C186	C:C:W102	13.06	Yes	Yes	2	9	9
648	C:C:F104	C:C:L108	6.09	Yes	No	2	7	5
649	C:C:N106	C:C:V177	4.43	No	No	0	3	4
650	C:C:C109	C:C:C186	7.28	No	Yes	2	9	9
651	C:C:D171	C:C:H113	6.3	Yes	Yes	2	4	6
652	C:C:A175	C:C:H113	4.39	No	Yes	0	4	6
653	C:C:C186	C:C:H113	2.95	Yes	Yes	2	9	6
654	C:C:H113	C:C:R188	4.51	Yes	Yes	2	6	5
655	C:C:T168	C:C:V114	4.76	No	No	0	6	5
656	C:C:D171	C:C:V114	2.92	Yes	No	0	4	5
657	C:C:F172	C:C:V114	9.18	No	No	0	4	5
658	C:C:L120	C:C:Y116	4.69	No	Yes	0	7	6
659	C:C:E288	C:C:Y116	3.37	No	Yes	2	5	6
660	C:C:F292	C:C:Y116	7.22	Yes	Yes	2	7	6
661	C:C:T117	C:C:Y121	3.75	No	Yes	0	5	7
662	C:C:T117	C:C:T168	3.14	No	No	0	5	6
663	C:C:D171	C:C:T117	7.23	Yes	No	0	4	5
664	C:C:H294	C:C:N119	10.2	Yes	No	2	9	8
665	C:C:H203	C:C:L120	7.71	No	No	0	4	7
666	C:C:L120	C:C:W252	4.56	No	Yes	0	7	9
667	C:C:L167	C:C:Y121	8.21	No	Yes	0	5	7
668	C:C:Q202	C:C:Y121	5.64	No	Yes	0	3	7
669	C:C:H203	C:C:Y121	5.44	No	Yes	0	4	7
670	C:C:V206	C:C:Y121	5.05	No	Yes	0	4	7
671	C:C:I126	C:C:S122	3.1	Yes	Yes	12	7	7
672	C:C:S122	C:C:V160	3.23	Yes	Yes	12	7	7
673	C:C:S122	C:C:W161	8.65	Yes	Yes	12	7	9
674	C:C:F248	C:C:S123	5.28	Yes	No	2	9	9
675	C:C:H294	C:C:S123	5.58	Yes	No	2	9	9
676	C:C:P211	C:C:V124	3.53	No	No	0	9	7
677	C:C:F248	C:C:V124	3.93	Yes	No	0	9	7
678	C:C:L125	C:C:V160	2.98	No	Yes	0	5	7
679	C:C:I126	C:C:I130	2.94	Yes	No	0	7	8
680	C:C:I126	C:C:V160	7.68	Yes	Yes	12	7	7
681	C:C:I245	C:C:L127	2.85	No	No	0	7	8
682	C:C:F248	C:C:L127	8.53	Yes	No	0	9	8
683	C:C:A128	C:C:I215	3.25	No	No	0	7	7
684	C:C:F129	C:C:L151	4.87	No	No	23	5	4
685	C:C:F129	C:C:G159	3.01	No	No	0	5	3
686	C:C:I215	C:C:S131	9.29	No	No	0	7	9
687	C:C:C218	C:C:S131	3.44	No	No	0	6	9
688	C:C:S131	C:C:Y219	5.09	No	No	0	9	8
689	C:C:D133	C:C:R148	7.15	No	No	0	8	6
690	C:C:V139	C:C:Y135	7.57	No	Yes	24	7	8
691	C:C:H140	C:C:Y135	5.44	No	Yes	24	6	8
692	C:C:C218	C:C:Y135	6.72	No	Yes	0	6	8
693	C:C:I221	C:C:Y135	4.84	No	Yes	0	4	8
694	C:C:L136	C:C:S144	6.01	No	No	0	5	5
695	C:C:A137	C:C:R148	4.15	No	No	0	8	6
696	C:C:I138	C:C:I222	10.3	No	No	0	8	8
697	C:C:I138	C:C:K234	2.91	No	No	0	8	7
698	C:C:H140	C:C:V139	8.3	No	No	24	6	7
699	C:C:K225	C:C:V139	3.04	No	No	0	4	7
700	C:C:P147	C:C:R146	8.65	No	No	0	4	5
701	C:C:L150	C:C:V155	2.98	No	No	0	4	2
702	C:C:V156	C:C:Y157	5.05	No	No	0	5	7
703	C:C:I162	C:C:V158	3.07	No	No	0	4	4
704	C:C:V160	C:C:W161	3.68	Yes	Yes	12	7	9
705	C:C:I162	C:C:P163	3.39	No	No	0	4	4
706	C:C:F174	C:C:P170	2.89	Yes	No	0	4	8
707	C:C:F199	C:C:P170	5.78	Yes	No	0	5	8
708	C:C:D171	C:C:R188	8.34	Yes	Yes	2	4	5
709	C:C:F174	C:C:I173	3.77	Yes	No	0	4	3
710	C:C:F174	C:C:Y190	8.25	Yes	Yes	2	4	4
711	C:C:F174	C:C:P191	4.33	Yes	No	0	4	5
712	C:C:F174	C:C:W195	5.01	Yes	No	2	4	5
713	C:C:F189	C:C:N176	4.83	No	No	0	3	4
714	C:C:I185	C:C:S178	3.1	No	No	0	3	1
715	C:C:F189	C:C:S178	5.28	No	No	0	3	1
716	C:C:E179	C:C:Y184	10.1	No	No	0	2	5
717	C:C:A180	C:C:R183	8.3	No	No	0	1	3
718	C:C:D181	C:C:R183	10.72	No	No	0	2	3
719	C:C:R188	C:C:Y190	13.38	Yes	Yes	2	5	4
720	C:C:F199	C:C:R188	3.21	Yes	Yes	2	5	5
721	C:C:W195	C:C:Y190	3.86	No	Yes	2	5	4
722	C:C:V196	C:C:Y190	6.31	No	Yes	0	4	4
723	C:C:F199	C:C:Y190	7.22	Yes	Yes	2	5	4
724	C:C:N192	C:C:P191	4.89	No	No	0	1	5
725	C:C:N192	C:C:W195	7.91	No	No	0	1	5
726	C:C:D193	C:C:L266	6.79	No	No	0	1	3
727	C:C:S263	C:C:V197	4.85	No	No	0	5	3
728	C:C:L266	C:C:V197	4.47	No	No	0	3	3
729	C:C:L267	C:C:V197	8.94	No	No	0	1	3
730	C:C:I259	C:C:Q200	4.12	Yes	No	0	5	5
731	C:C:Q200	C:C:S263	5.78	No	No	0	5	5
732	C:C:F201	C:C:S263	10.57	No	No	0	4	5
733	C:C:F201	C:C:F264	5.36	No	No	0	4	4
734	C:C:H203	C:C:Y256	10.89	No	Yes	0	4	8
735	C:C:I204	C:C:Y256	4.84	No	Yes	2	5	8
736	C:C:I204	C:C:I259	5.89	No	Yes	2	5	5
737	C:C:I209	C:C:M205	8.75	No	No	0	4	4
738	C:C:L210	C:C:M205	4.24	No	No	0	6	4
739	C:C:G207	C:C:Y256	4.35	No	Yes	0	5	8
740	C:C:L208	C:C:Y256	10.55	No	Yes	0	8	8
741	C:C:F249	C:C:G212	3.01	No	No	0	4	6
742	C:C:F249	C:C:I215	3.77	No	No	0	4	7
743	C:C:V242	C:C:Y219	7.57	No	No	0	4	8
744	C:C:I245	C:C:Y219	4.84	No	No	0	7	8
745	C:C:I222	C:C:L238	2.85	No	No	0	8	5
746	C:C:H232	C:C:K234	9.17	No	No	0	4	7
747	C:C:L238	C:C:V242	4.47	No	No	0	5	4
748	C:C:K239	C:C:V242	3.04	No	No	0	6	4
749	C:C:I243	C:C:K239	2.91	No	No	0	5	6
750	C:C:T240	C:C:T241	3.14	No	No	0	7	7
751	C:C:I243	C:C:L301	5.71	No	No	0	5	7
752	C:C:A247	C:C:L297	4.73	No	No	0	6	6
753	C:C:F248	C:C:F249	5.36	Yes	No	0	9	4
754	C:C:F248	C:C:W252	11.02	Yes	Yes	2	9	9
755	C:C:F248	C:C:H294	6.79	Yes	Yes	2	9	9
756	C:C:W252	C:C:Y255	6.75	Yes	Yes	2	9	7
757	C:C:W252	C:C:Y256	4.82	Yes	Yes	2	9	8
758	C:C:A291	C:C:W252	3.89	No	Yes	0	8	9
759	C:C:H294	C:C:W252	11.64	Yes	Yes	2	9	9
760	C:C:P254	C:C:T287	3.5	No	No	0	9	6
761	C:C:Y255	C:C:Y256	2.98	Yes	Yes	2	7	8
762	C:C:I259	C:C:Y255	9.67	Yes	Yes	2	5	7
763	C:C:E288	C:C:Y255	8.98	No	Yes	2	5	7
764	C:C:I259	C:C:Y256	3.63	Yes	Yes	2	5	8
765	C:C:I259	C:C:I284	4.42	Yes	No	0	5	4
766	C:C:I261	C:C:V280	3.07	Yes	No	0	5	5
767	C:C:D262	C:C:E277	3.9	Yes	No	25	5	2
768	C:C:D262	C:C:V280	4.38	Yes	No	0	5	5
769	C:C:D262	C:C:H281	8.82	Yes	No	25	5	4
770	C:C:D262	C:C:I284	4.2	Yes	No	0	5	4
771	C:C:F264	C:C:I269	5.02	No	No	0	4	1
772	C:C:I265	C:C:I270	5.89	No	No	0	3	5
773	C:C:E268	C:C:K271	5.4	No	No	0	2	3
774	C:C:F276	C:C:V280	5.24	No	No	0	1	5
775	C:C:E277	C:C:H281	19.69	No	No	25	2	4
776	C:C:K282	C:C:N278	4.2	No	No	0	2	3
777	C:C:T287	C:C:W283	9.7	No	Yes	0	6	6
778	C:C:E288	C:C:F292	8.16	No	Yes	2	5	7
779	C:C:C295	C:C:H294	7.37	No	Yes	2	9	9
780	C:C:C296	C:C:I300	3.27	No	No	0	7	6
781	C:C:N298	C:C:P299	3.26	Yes	No	0	9	9
782	P:P:K25	P:P:K271	2.87	No	No	0	4	3
783	P:P:E26	P:P:P27	11	No	No	0	2	5
784	P:P:C28	P:P:E26	3.04	No	No	0	9	2
785	P:P:E26	P:P:F29	12.83	No	No	0	2	4
786	P:P:C28	P:P:R30	6.96	No	No	0	9	5
787	P:P:C274	P:P:F29	9.78	No	No	0	5	4
788	P:P:E31	P:P:N33	7.89	No	No	0	5	6
789	P:P:A34	P:P:E31	4.53	No	No	0	1	5
790	P:P:E31	P:P:N278	3.94	No	No	0	5	3
791	P:P:E32	P:P:N33	3.94	No	No	0	4	6
792	P:P:F36	P:P:I39	3.77	No	Yes	1	4	5
793	P:P:F36	P:P:F40	9.65	No	No	0	4	5
794	P:P:K282	P:P:N37	5.6	No	No	0	2	3
795	P:P:N37	P:P:S285	4.47	No	No	0	3	5
796	P:P:I286	P:P:N37	7.08	No	No	0	6	3
797	P:P:F40	P:P:I44	7.54	No	No	0	5	5
798	P:P:L41	P:P:Y45	5.86	No	Yes	5	6	7
799	P:P:L41	P:P:S285	4.5	No	No	0	6	5
800	P:P:A289	P:P:L41	3.15	No	No	5	4	6
801	P:P:A98	P:P:P42	5.61	No	No	0	5	5
802	P:P:P42	P:P:V99	3.53	No	No	1	5	4
803	P:P:I44	P:P:I48	2.94	No	No	0	5	7
804	P:P:W94	P:P:Y45	2.89	Yes	Yes	0	7	7
805	P:P:A289	P:P:Y45	4	No	Yes	5	4	7
806	P:P:F292	P:P:Y45	7.22	Yes	Yes	5	7	7
807	P:P:I48	P:P:L91	2.85	No	No	0	7	8
808	P:P:F293	P:P:I48	8.79	No	No	0	5	7
809	P:P:F49	P:P:P92	7.22	No	No	0	6	9
810	P:P:C296	P:P:T51	3.38	No	No	0	7	5
811	P:P:G52	P:P:V88	3.68	No	No	0	8	6
812	P:P:I53	P:P:V88	4.61	No	No	0	5	6
813	P:P:G55	P:P:V54	3.68	No	No	0	8	4
814	P:P:G55	P:P:P299	4.06	No	Yes	0	8	9
815	P:P:N56	P:P:S81	5.96	Yes	No	0	9	9
816	P:P:D84	P:P:N56	6.73	Yes	Yes	0	9	9
817	P:P:N56	P:P:P299	3.26	Yes	Yes	0	9	9
818	P:P:S81	P:P:V59	8.08	No	No	0	9	8
819	P:P:P299	P:P:V59	3.53	Yes	No	0	9	8
820	P:P:I60	P:P:V82	3.07	No	No	0	7	5
821	P:P:I60	P:P:L85	2.85	No	No	0	7	7
822	P:P:M63	P:P:V62	3.04	Yes	No	26	6	7
823	P:P:K68	P:P:V62	3.04	No	No	26	6	7
824	P:P:K68	P:P:M63	4.32	No	Yes	26	6	6
825	P:P:L69	P:P:M63	5.65	No	Yes	0	6	6
826	P:P:M63	P:P:Y302	8.38	Yes	No	0	6	9
827	P:P:K75	P:P:L69	7.05	No	No	0	6	6
828	P:P:S71	P:P:T73	3.2	No	No	0	7	7
829	P:P:D74	P:P:S71	7.36	No	No	0	8	7
830	P:P:D133	P:P:M72	4.16	No	Yes	27	8	6
831	P:P:M72	P:P:R148	6.2	Yes	No	27	6	6
832	P:P:A152	P:P:M72	3.22	No	Yes	0	3	6
833	P:P:D74	P:P:Y302	6.9	No	No	0	8	9
834	P:P:I130	P:P:Y76	4.84	No	Yes	0	8	7
835	P:P:D133	P:P:Y76	6.9	No	Yes	0	8	7
836	P:P:L151	P:P:Y76	3.52	No	Yes	0	4	7
837	P:P:V156	P:P:Y76	5.05	No	Yes	0	5	7
838	P:P:R77	P:P:T240	5.17	Yes	No	0	8	7
839	P:P:L244	P:P:R77	3.64	No	Yes	0	7	8
840	P:P:N298	P:P:R77	3.62	No	Yes	0	9	8
841	P:P:R77	P:P:Y302	14.4	Yes	No	0	8	9
842	P:P:H79	P:P:Y157	3.27	No	No	0	9	7
843	P:P:H79	P:P:W161	3.17	No	No	0	9	9
844	P:P:D84	P:P:L80	4.07	Yes	No	0	9	9
845	P:P:I126	P:P:L80	4.28	Yes	No	0	7	9
846	P:P:N298	P:P:S81	5.96	No	No	0	9	9
847	P:P:A83	P:P:S122	3.42	No	Yes	0	8	7
848	P:P:D84	P:P:N119	4.04	Yes	No	0	9	8
849	P:P:C295	P:P:D84	10.89	No	Yes	0	9	9
850	P:P:F87	P:P:L91	3.65	Yes	No	0	7	8
851	P:P:F87	P:P:W94	4.01	Yes	Yes	0	7	7
852	P:P:F87	P:P:Y116	7.22	Yes	Yes	5	7	6
853	P:P:F87	P:P:N119	13.29	Yes	No	0	7	8
854	P:P:F292	P:P:F87	15	Yes	Yes	5	7	7
855	P:P:F93	P:P:T90	5.19	Yes	No	4	6	6
856	P:P:T90	P:P:V112	3.17	No	Yes	4	6	5
857	P:P:I115	P:P:T90	4.56	No	No	0	5	6
858	P:P:F93	P:P:W102	3.01	Yes	Yes	4	6	9
859	P:P:F104	P:P:F93	7.5	No	Yes	4	7	6
860	P:P:F93	P:P:L108	3.65	Yes	No	0	6	5
861	P:P:F93	P:P:V112	3.93	Yes	Yes	4	6	5
862	P:P:D97	P:P:W94	3.35	No	Yes	0	5	7
863	P:P:V112	P:P:W94	7.36	Yes	Yes	0	5	7
864	P:P:H113	P:P:W94	5.29	Yes	Yes	0	6	7
865	P:P:F104	P:P:V96	5.24	No	No	0	7	5
866	P:P:D97	P:P:W102	7.82	No	Yes	0	5	9
867	P:P:N101	P:P:R183	12.05	No	No	0	4	3
868	P:P:F104	P:P:W102	15.03	No	Yes	4	7	9
869	P:P:C109	P:P:W102	5.22	No	Yes	4	9	9
870	P:P:V112	P:P:W102	7.36	Yes	Yes	4	5	9
871	P:P:C186	P:P:W102	16.98	No	Yes	4	9	9
872	P:P:N106	P:P:N176	4.09	No	No	0	3	4
873	P:P:N106	P:P:V177	4.43	No	No	0	3	4
874	P:P:C109	P:P:V177	3.42	No	No	0	9	4
875	P:P:C109	P:P:C186	7.28	No	No	4	9	9
876	P:P:K110	P:P:N176	4.2	No	No	0	7	4
877	P:P:D171	P:P:H113	6.3	Yes	Yes	4	4	6
878	P:P:A175	P:P:H113	2.93	No	Yes	0	4	6
879	P:P:C186	P:P:H113	2.95	No	Yes	4	9	6
880	P:P:H113	P:P:R188	3.39	Yes	Yes	4	6	5
881	P:P:T168	P:P:V114	6.35	No	No	0	6	5
882	P:P:L120	P:P:Y116	5.86	No	Yes	0	7	6
883	P:P:Y116	P:P:Y255	2.98	Yes	Yes	5	6	7
884	P:P:F292	P:P:Y116	6.19	Yes	Yes	5	7	6
885	P:P:T117	P:P:T168	6.28	No	No	4	5	6
886	P:P:D171	P:P:T117	8.67	Yes	No	4	4	5
887	P:P:H294	P:P:N119	5.1	Yes	No	0	9	8
888	P:P:H203	P:P:L120	9	Yes	No	0	4	7
889	P:P:L120	P:P:W252	3.42	No	Yes	0	7	9
890	P:P:L167	P:P:Y121	11.72	No	Yes	0	5	7
891	P:P:Q202	P:P:Y121	4.51	No	Yes	0	3	7
892	P:P:H203	P:P:Y121	5.44	Yes	Yes	0	4	7
893	P:P:V206	P:P:Y121	3.79	No	Yes	0	4	7
894	P:P:I126	P:P:S122	3.1	Yes	Yes	14	7	7
895	P:P:S122	P:P:V160	3.23	Yes	Yes	14	7	7
896	P:P:S122	P:P:W161	11.12	Yes	No	14	7	9
897	P:P:F248	P:P:S123	6.61	Yes	No	5	9	9
898	P:P:H294	P:P:S123	5.58	Yes	No	5	9	9
899	P:P:P211	P:P:V124	3.53	No	No	0	9	7
900	P:P:F248	P:P:V124	3.93	Yes	No	0	9	7
901	P:P:L125	P:P:V160	2.98	No	Yes	0	5	7
902	P:P:I126	P:P:I130	2.94	Yes	No	0	7	8
903	P:P:I126	P:P:V160	7.68	Yes	Yes	14	7	7
904	P:P:I245	P:P:L127	5.71	No	No	0	7	8
905	P:P:F248	P:P:L127	6.09	Yes	No	0	9	8
906	P:P:A128	P:P:I215	3.25	No	No	0	7	7
907	P:P:F129	P:P:L151	4.87	No	No	0	5	4
908	P:P:F129	P:P:V156	7.87	No	No	0	5	5
909	P:P:F129	P:P:G159	3.01	No	No	0	5	3
910	P:P:I215	P:P:S131	9.29	No	No	0	7	9
911	P:P:C218	P:P:S131	3.44	No	No	0	6	9
912	P:P:S131	P:P:Y219	5.09	No	No	0	9	8
913	P:P:D133	P:P:R148	13.1	No	No	27	8	6
914	P:P:R134	P:P:T241	3.88	No	No	0	9	7
915	P:P:L136	P:P:Y135	3.52	No	Yes	0	5	8
916	P:P:V139	P:P:Y135	7.57	Yes	Yes	0	7	8
917	P:P:C218	P:P:Y135	6.72	No	Yes	0	6	8
918	P:P:I221	P:P:Y135	6.04	No	Yes	0	4	8
919	P:P:A137	P:P:R148	6.91	No	No	0	8	6
920	P:P:I138	P:P:V139	3.07	No	Yes	0	8	7
921	P:P:I138	P:P:I222	8.83	No	No	0	8	8
922	P:P:H140	P:P:V139	5.54	No	Yes	0	6	7
923	P:P:K225	P:P:V139	4.55	No	Yes	0	4	7
924	P:P:H140	P:P:N143	3.83	No	No	0	6	5
925	P:P:N143	P:P:T142	4.39	No	No	0	5	5
926	P:P:L150	P:P:V155	4.47	No	No	0	4	2
927	P:P:E153	P:P:K154	5.4	No	No	0	7	3
928	P:P:I162	P:P:V158	4.61	No	No	0	4	4
929	P:P:V160	P:P:W161	3.68	Yes	No	14	7	9
930	P:P:I162	P:P:P163	3.39	No	No	0	4	4
931	P:P:D171	P:P:T168	7.23	Yes	No	4	4	6
932	P:P:I169	P:P:P170	3.39	No	No	0	3	8
933	P:P:F199	P:P:P170	8.67	Yes	No	0	5	8
934	P:P:D171	P:P:R188	9.53	Yes	Yes	4	4	5
935	P:P:F174	P:P:I173	3.77	Yes	No	0	4	3
936	P:P:F174	P:P:Y190	6.19	Yes	Yes	4	4	4
937	P:P:F174	P:P:P191	5.78	Yes	No	0	4	5
938	P:P:F174	P:P:W195	7.02	Yes	Yes	4	4	5
939	P:P:F189	P:P:S178	6.61	No	No	0	3	1
940	P:P:E179	P:P:Y184	13.47	No	No	0	2	5
941	P:P:D181	P:P:R183	4.76	No	No	0	2	3
942	P:P:D187	P:P:R188	3.57	No	Yes	0	3	5
943	P:P:R188	P:P:Y190	15.43	Yes	Yes	4	5	4
944	P:P:W195	P:P:Y190	3.86	Yes	Yes	4	5	4
945	P:P:V196	P:P:Y190	5.05	No	Yes	0	4	4
946	P:P:F199	P:P:Y190	9.28	Yes	Yes	4	5	4
947	P:P:N192	P:P:P191	3.26	No	No	0	1	5
948	P:P:L194	P:P:N192	5.49	No	No	0	2	1
949	P:P:N192	P:P:W195	7.91	No	Yes	0	1	5
950	P:P:D193	P:P:L266	5.43	No	No	0	1	3
951	P:P:F199	P:P:W195	5.01	Yes	Yes	4	5	5
952	P:P:L266	P:P:V197	4.47	No	No	0	3	3
953	P:P:L267	P:P:V197	5.96	No	No	0	1	3
954	P:P:F199	P:P:Q202	5.86	Yes	No	0	5	3
955	P:P:I259	P:P:Q200	6.86	Yes	No	0	5	5
956	P:P:Q200	P:P:S263	4.33	No	No	0	5	5
957	P:P:F201	P:P:S263	5.28	No	No	0	4	5
958	P:P:H203	P:P:Y255	6.53	Yes	Yes	5	4	7
959	P:P:H203	P:P:Y256	8.71	Yes	Yes	5	4	8
960	P:P:I204	P:P:Y256	3.63	No	Yes	0	5	8
961	P:P:I204	P:P:I259	5.89	No	Yes	0	5	5
962	P:P:I209	P:P:M205	5.83	No	No	0	4	4
963	P:P:G207	P:P:Y256	2.9	No	Yes	0	5	8
964	P:P:L208	P:P:Y256	10.55	No	Yes	0	8	8
965	P:P:F249	P:P:G212	3.01	No	No	0	4	6
966	P:P:I215	P:P:I245	4.42	No	No	0	7	7
967	P:P:L238	P:P:Y219	7.03	No	No	0	5	8
968	P:P:V242	P:P:Y219	8.83	No	No	0	4	8
969	P:P:I222	P:P:L238	4.28	No	No	0	8	5
970	P:P:L226	P:P:R235	7.29	No	No	0	8	5
971	P:P:K234	P:P:S229	3.06	No	No	0	7	5
972	P:P:H232	P:P:K234	15.72	No	No	0	4	7
973	P:P:I243	P:P:L301	5.71	No	No	0	5	7
974	P:P:A247	P:P:L297	4.73	No	No	0	6	6
975	P:P:F248	P:P:F249	4.29	Yes	No	0	9	4
976	P:P:F248	P:P:W252	11.02	Yes	Yes	5	9	9
977	P:P:F248	P:P:H294	7.92	Yes	Yes	5	9	9
978	P:P:W252	P:P:Y255	7.72	Yes	Yes	5	9	7
979	P:P:W252	P:P:Y256	6.75	Yes	Yes	5	9	8
980	P:P:A291	P:P:W252	6.48	No	Yes	0	8	9
981	P:P:F292	P:P:W252	4.01	Yes	Yes	5	7	9
982	P:P:H294	P:P:W252	15.87	Yes	Yes	5	9	9
983	P:P:P254	P:P:T287	5.25	No	No	0	9	6
984	P:P:Y255	P:P:Y256	2.98	Yes	Yes	5	7	8
985	P:P:I259	P:P:Y255	12.09	Yes	Yes	0	5	7
986	P:P:E288	P:P:Y255	8.98	No	Yes	0	5	7
987	P:P:I259	P:P:I284	4.42	Yes	No	0	5	4
988	P:P:I261	P:P:V280	3.07	Yes	No	0	5	5
989	P:P:D262	P:P:V280	2.92	No	No	0	5	5
990	P:P:D262	P:P:H281	10.08	No	No	0	5	4
991	P:P:D262	P:P:I284	4.2	No	No	0	5	4
992	P:P:I265	P:P:I270	5.89	No	Yes	0	3	5
993	P:P:E277	P:P:I265	6.83	No	No	0	2	3
994	P:P:E268	P:P:K271	6.75	No	No	0	2	3
995	P:P:I269	P:P:I270	2.94	No	Yes	0	1	5
996	P:P:I270	P:P:Q272	5.49	Yes	No	0	5	2
997	P:P:G273	P:P:Q272	4.93	No	No	0	5	2
998	P:P:F276	P:P:V280	5.24	Yes	No	0	1	5
999	P:P:T287	P:P:W283	12.13	No	Yes	0	6	6
1000	P:P:E288	P:P:F292	10.49	No	Yes	0	5	7
1001	P:P:C296	P:P:F293	6.98	No	No	0	7	5
1002	P:P:C295	P:P:H294	7.37	No	Yes	0	9	9
1003	P:P:N298	P:P:P299	6.52	No	Yes	0	9	9
1004	L:L:I320	L:L:N300	5.66	No	No	0	8	9
1005	L:L:N300	L:L:N321	4.09	No	No	0	9	7
1006	L:L:K301	L:L:V319	7.59	No	No	0	8	1
1007	L:L:S316	L:L:V303	8.08	No	No	0	5	8
1008	L:L:P318	L:L:V303	3.53	No	No	0	4	8
1009	L:L:L304	L:L:M309	4.24	No	No	0	4	7
1010	L:L:F314	L:L:K313	3.72	No	No	0	4	5
1011	L:L:K317	L:L:P318	3.35	No	No	0	8	4
1012	R:R:L210	R:R:M205	2.83	No	No	0	6	4
1013	C:C:K234	C:C:L226	2.82	No	No	0	7	8
1014	R:R:G258	R:R:W283	2.81	No	Yes	0	4	6
1015	C:C:G258	C:C:W283	2.81	No	Yes	0	4	6
1016	P:P:G258	P:P:W283	2.81	No	Yes	0	4	6
1017	C:C:D262	C:C:I265	2.8	Yes	No	0	5	3
1018	R:R:C28	R:R:R30	2.79	No	No	0	9	5
1019	R:R:H140	R:R:S144	2.79	Yes	No	0	6	5
1020	R:R:C296	R:R:F293	2.79	No	Yes	0	7	5
1021	S:S:H140	S:S:S144	2.79	Yes	No	0	6	5
1022	S:S:H232	S:S:S229	2.79	No	No	0	4	5
1023	C:C:H140	C:C:S144	2.79	No	No	0	6	5
1024	C:C:H232	C:C:S229	2.79	No	No	0	4	5
1025	C:C:C296	C:C:F293	2.79	No	No	0	7	5
1026	P:P:H140	P:P:S144	2.79	No	No	0	6	5
1027	C:C:L253	R:R:L50	2.77	No	No	0	5	5
1028	R:R:L127	R:R:L244	2.77	No	No	0	8	7
1029	R:R:L244	R:R:L297	2.77	No	No	0	7	6
1030	S:S:L127	S:S:L244	2.77	No	No	0	8	7
1031	S:S:L208	S:S:L253	2.77	No	No	0	8	5
1032	S:S:L244	S:S:L297	2.77	No	No	0	7	6
1033	P:P:L50	S:S:L253	2.77	No	No	0	5	5
1034	S:S:L297	S:S:L301	2.77	No	No	0	6	7
1035	C:C:L244	C:C:L297	2.77	No	No	0	7	6
1036	C:C:L297	C:C:L301	2.77	No	No	0	6	7
1037	P:P:L132	P:P:L136	2.77	No	No	0	6	5
1038	P:P:A137	P:P:R134	2.77	No	No	0	8	9
1039	P:P:A180	P:P:R183	2.77	No	No	0	1	3
1040	R:R:L85	R:R:N56	2.75	No	No	0	7	9
1041	P:P:L85	P:P:N56	2.75	No	Yes	0	7	9
1042	S:S:I259	S:S:Q200	2.74	Yes	No	0	5	5
1043	S:S:E277	S:S:I265	2.73	No	No	0	2	3
1044	R:R:N33	R:R:N37	2.72	No	Yes	0	6	3
1045	C:C:N33	C:C:N37	2.72	No	Yes	0	6	3
1046	C:C:N106	C:C:N176	2.72	No	No	0	3	4
1047	R:R:K236	R:R:Q233	2.71	No	No	0	8	5
1048	C:C:K236	C:C:Q233	2.71	No	No	0	8	5
1049	S:S:E153	S:S:K149	2.7	No	No	0	7	6
1050	C:C:E153	C:C:K149	2.7	No	No	0	7	6
1051	R:R:A95	R:R:Y45	2.67	No	Yes	0	7	7
1052	S:S:A95	S:S:Y45	2.67	No	Yes	0	7	7
1053	C:C:A95	C:C:Y45	2.67	No	Yes	0	7	7
1054	P:P:A95	P:P:Y45	2.67	No	Yes	0	7	7
1055	S:S:L61	S:S:Q66	2.66	No	No	0	4	4
1056	R:R:F264	R:R:S260	2.64	No	No	0	4	5
1057	R:R:Q272	S:S:N101	2.64	No	No	0	2	4
1058	S:S:F264	S:S:S260	2.64	No	No	0	4	5
1059	C:C:F264	C:C:S260	2.64	No	No	0	4	5
1060	P:P:F264	P:P:S260	2.64	No	No	0	4	5
1061	C:C:E275	R:R:N35	2.63	No	No	0	3	3
1062	P:P:F49	P:P:V88	2.62	No	No	0	6	6
1063	P:P:F172	P:P:V114	2.62	No	No	0	4	5
1064	R:R:R134	R:R:T73	2.59	Yes	No	0	9	7
1065	S:S:R77	S:S:T73	2.59	Yes	No	0	8	7
1066	S:S:R77	S:S:T240	2.59	Yes	No	0	8	7
1067	C:C:R134	C:C:T73	2.59	No	No	0	9	7
1068	R:R:H140	R:R:L136	2.57	Yes	No	0	6	5
1069	S:S:H140	S:S:N143	2.55	Yes	No	0	6	5
1070	R:R:F293	R:R:I47	2.51	Yes	No	0	5	4
1071	R:R:I138	R:R:R235	2.51	No	No	0	8	5
1072	R:R:I185	R:R:R183	2.51	Yes	No	0	3	3
1073	R:R:F304	R:R:I300	2.51	No	No	0	6	6
1074	S:S:F36	S:S:I39	2.51	No	Yes	0	4	5
1075	S:S:I185	S:S:R183	2.51	No	No	0	3	3
1076	C:C:F40	C:C:I286	2.51	No	No	0	5	6
1077	C:C:F304	C:C:I300	2.51	No	No	0	6	6
1078	P:P:F276	P:P:I270	2.51	Yes	Yes	0	1	5
1079	P:P:F304	P:P:I300	2.51	No	No	0	6	6
1080	R:R:F172	R:R:K110	2.48	No	No	0	4	7
1081	S:S:K68	S:S:R70	2.48	No	No	0	6	6
1082	S:S:K149	S:S:R146	2.48	No	No	0	6	5
1083	C:C:K38	P:P:F276	2.48	No	Yes	0	4	1
1084	C:C:H232	C:C:Q233	2.47	No	No	0	4	5
1085	R:R:V198	R:R:W195	2.45	No	Yes	0	3	5
1086	S:S:V82	S:S:W161	2.45	No	Yes	0	5	9
1087	R:R:F129	R:R:L151	2.44	No	No	0	5	4
1088	S:S:F107	S:S:L108	2.44	No	No	0	1	5
1089	P:P:F49	P:P:L91	2.44	No	No	0	6	8
1090	P:P:L301	P:P:R77	2.43	No	Yes	0	7	8
1091	S:S:D187	S:S:F189	2.39	No	No	0	3	3
1092	C:C:D187	C:C:F189	2.39	No	No	0	3	3
1093	P:P:D187	P:P:F189	2.39	No	No	0	3	3
1094	S:S:D187	S:S:R188	2.38	No	Yes	0	3	5
1095	R:R:Q145	R:R:R148	2.34	No	Yes	0	5	6
1096	S:S:L136	S:S:Y135	2.34	No	Yes	0	5	8
1097	S:S:Q145	S:S:R148	2.34	No	Yes	0	5	6
1098	C:C:E26	C:C:F29	2.33	No	No	0	2	4
1099	R:R:L165	R:R:W161	2.28	No	Yes	0	3	9
1100	R:R:Q66	R:R:Y65	2.25	Yes	No	0	4	5
1101	P:P:F201	P:P:F264	2.14	No	No	0	4	4
1102	R:R:C28	R:R:P27	1.88	No	No	0	9	5
1103	S:S:G231	S:S:S229	1.86	No	No	0	4	5
1104	C:C:G231	C:C:S229	1.86	No	No	0	4	5
1105	R:R:G55	R:R:V54	1.84	No	No	0	8	4
1106	R:R:G159	R:R:V158	1.84	No	No	0	3	4
1107	C:C:G159	C:C:V158	1.84	No	No	0	3	4
1108	R:R:P147	R:R:S144	1.78	No	No	0	4	5
1109	R:R:G64	R:R:M63	1.75	No	Yes	0	2	6
1110	S:S:C218	S:S:S217	1.72	No	No	0	6	3
1111	R:R:G57	R:R:L85	1.71	No	No	0	3	7
1112	R:R:A180	R:R:S178	1.71	No	No	0	1	1
1113	R:R:C218	R:R:V214	1.71	Yes	No	0	6	6
1114	R:R:G306	R:R:L301	1.71	No	No	0	8	7
1115	S:S:G55	S:S:L58	1.71	No	No	0	8	5
1116	S:S:G64	S:S:L78	1.71	No	No	0	2	5
1117	S:S:A164	S:S:S122	1.71	No	Yes	0	7	7
1118	C:C:A164	C:C:S122	1.71	No	Yes	0	7	7
1119	C:C:C186	C:C:V177	1.71	Yes	No	0	9	4
1120	C:C:A180	C:C:S178	1.71	No	No	0	1	1
1121	P:P:G55	P:P:L58	1.71	No	No	0	8	5
1122	P:P:G64	P:P:L78	1.71	No	No	0	2	5
1123	P:P:A164	P:P:S122	1.71	No	Yes	0	7	7
1124	R:R:A100	R:R:V96	1.7	No	No	0	5	5
1125	R:R:A100	R:R:V99	1.7	No	No	0	5	4
1126	R:R:A164	R:R:V118	1.7	No	No	0	7	5
1127	P:P:A100	P:P:V96	1.7	No	No	0	5	5
1128	P:P:A128	P:P:V214	1.7	No	No	0	7	6
1129	C:C:I169	C:C:P170	1.69	No	No	0	3	8
1130	L:L:I308	L:L:P305	1.69	No	No	0	5	5
1131	S:S:L210	S:S:P211	1.64	No	No	0	6	9
1132	S:S:C296	S:S:I300	1.64	No	No	0	7	6
1133	C:C:L136	C:C:P147	1.64	No	No	0	5	4
1134	C:C:L210	C:C:P211	1.64	No	No	0	6	9
1135	P:P:L210	P:P:P211	1.64	No	No	0	6	9
1136	P:P:C296	P:P:I300	1.64	No	No	0	7	6
1137	L:L:L304	L:L:P305	1.64	No	No	0	4	5
1138	C:C:V62	P:P:S227	1.62	Yes	No	0	7	4
1139	P:P:S263	P:P:V197	1.62	No	No	0	5	3
1140	S:S:A175	S:S:K110	1.61	No	No	0	4	7
1141	C:C:A34	C:C:K282	1.61	No	No	0	1	2
1142	P:P:A34	P:P:K38	1.61	No	No	0	1	4
1143	S:S:V155	S:S:V158	1.6	No	No	0	2	4
1144	C:C:V155	C:C:V158	1.6	No	No	0	2	4
1145	P:P:V114	P:P:V118	1.6	No	No	0	5	5
1146	P:P:V155	P:P:V158	1.6	No	No	0	2	4
1147	R:R:C218	R:R:L132	1.59	Yes	No	0	6	6
1148	R:R:C220	S:S:L58	1.59	No	No	0	3	5
1149	P:P:L58	S:S:C220	1.59	No	No	0	5	3
1150	C:C:L58	P:P:C220	1.59	No	No	0	5	3
1151	C:C:T168	C:C:V118	1.59	No	No	0	6	5
1152	P:P:C251	P:P:L297	1.59	No	No	0	8	6
1153	S:S:E26	S:S:P27	1.57	No	No	0	2	5
1154	R:R:I213	R:R:S217	1.55	No	No	0	3	3
1155	S:S:I60	S:S:S81	1.55	No	Yes	0	7	9
1156	C:C:I213	C:C:S217	1.55	No	No	0	3	3
1157	P:P:I185	P:P:S178	1.55	No	No	0	3	1
1158	C:C:I223	R:R:V62	1.54	No	No	0	4	7
1159	R:R:I115	R:R:V118	1.54	No	No	0	5	5
1160	R:R:A180	R:R:D182	1.54	No	No	0	1	6
1161	C:C:V62	P:P:I223	1.54	Yes	No	0	7	4
1162	R:R:I89	R:R:T90	1.52	No	Yes	0	4	6
1163	S:S:C28	S:S:E26	1.52	No	No	0	9	2
1164	S:S:I89	S:S:T90	1.52	No	Yes	0	4	6
1165	S:S:M205	S:S:V206	1.52	No	No	0	4	4
1166	S:S:C274	S:S:E277	1.52	No	No	0	5	2
1167	P:P:I39	S:S:T279	1.52	Yes	No	0	5	2
1168	C:C:I89	C:C:T90	1.52	No	No	0	4	6
1169	P:P:M205	P:P:V206	1.52	No	No	0	4	4
1170	P:P:K239	P:P:V242	1.52	No	No	0	6	4
1171	R:R:F104	R:R:G105	1.51	Yes	No	0	7	8
1172	R:R:F249	R:R:G212	1.51	No	No	0	4	6
1173	P:P:L61	S:S:S224	1.5	No	No	0	4	4
1174	R:R:L78	R:R:V82	1.49	No	No	0	5	5
1175	R:R:L246	R:R:V242	1.49	No	No	0	5	4
1176	S:S:L165	S:S:V118	1.49	No	No	0	3	5
1177	C:C:N37	C:C:S285	1.49	Yes	No	0	3	5
1178	C:C:L165	C:C:V118	1.49	No	No	0	3	5
1179	P:P:L61	P:P:V62	1.49	No	No	0	4	7
1180	P:P:L165	P:P:V118	1.49	No	No	0	3	5
1181	P:P:L151	P:P:V155	1.49	No	No	0	4	2
1182	P:P:L194	P:P:V198	1.49	No	No	0	2	3
1183	P:P:L246	P:P:V242	1.49	No	No	0	5	4
1184	R:R:I209	R:R:I213	1.47	No	No	0	4	3
1185	S:S:I138	S:S:I222	1.47	No	Yes	0	8	8
1186	S:S:I209	S:S:I213	1.47	No	No	0	4	3
1187	C:C:I209	C:C:I213	1.47	No	No	0	4	3
1188	P:P:I53	P:P:I89	1.47	No	No	0	5	4
1189	S:S:N143	S:S:T142	1.46	No	No	0	5	5
1190	C:C:N143	C:C:T142	1.46	No	No	0	5	5
1191	S:S:I243	S:S:K239	1.45	No	No	0	5	6
1192	P:P:I138	P:P:K234	1.45	No	No	0	8	7
1193	R:R:P147	R:R:R146	1.44	No	No	0	4	5
1194	C:C:K149	C:C:M72	1.44	No	Yes	0	6	6
1195	P:P:K149	P:P:M72	1.44	No	Yes	0	6	6
1196	P:P:P147	P:P:R146	1.44	No	No	0	4	5
1197	L:L:V319	R:R:E26	1.43	No	No	0	1	2
1198	R:R:I60	R:R:L61	1.43	No	No	0	7	4
1199	R:R:I162	R:R:L166	1.43	No	No	0	4	4
1200	R:R:I222	R:R:L226	1.43	Yes	No	0	8	8
1201	S:S:I44	S:S:L290	1.43	No	No	0	5	7
1202	S:S:I286	S:S:L290	1.43	No	No	0	6	7
1203	C:C:I60	C:C:L78	1.43	No	No	0	7	5
1204	C:C:I162	C:C:L166	1.43	No	No	0	4	4
1205	P:P:I44	P:P:L290	1.43	No	No	0	5	7
1206	P:P:I60	P:P:L78	1.43	No	No	0	7	5
1207	P:P:I115	P:P:L86	1.43	No	No	0	5	7
1208	P:P:I222	P:P:L226	1.43	No	No	0	8	8
1209	S:S:K154	S:S:L150	1.41	No	No	0	3	4
1210	C:C:K154	C:C:L150	1.41	No	No	0	3	4
1211	P:P:K154	P:P:L150	1.41	No	No	0	3	4
1212	R:R:K282	R:R:N278	1.4	No	No	0	2	3
1213	S:S:C251	S:S:F293	1.4	No	No	0	8	5
1214	C:C:K110	C:C:N176	1.4	No	No	0	7	4
1215	C:C:C251	C:C:F293	1.4	No	No	0	8	5
1216	P:P:C251	P:P:F293	1.4	No	No	0	8	5
1217	L:L:K301	L:L:N321	1.4	No	No	0	8	7
1218	S:S:A303	S:S:F304	1.39	No	No	0	7	6
1219	R:R:A237	R:R:R134	1.38	No	Yes	0	7	9
1220	S:S:A237	S:S:R134	1.38	No	No	0	7	9
1221	C:C:L132	C:C:L136	1.38	No	No	0	6	5
1222	C:C:L132	C:C:L151	1.38	No	No	0	6	4
1223	P:P:A237	P:P:R134	1.38	No	No	0	7	9
1224	R:R:L194	R:R:N192	1.37	No	No	0	2	1
1225	S:S:L194	S:S:N192	1.37	No	Yes	0	2	1
1226	P:P:K236	P:P:Q233	1.36	No	No	0	8	5
1227	R:R:E153	R:R:K75	1.35	No	No	0	7	6
1228	S:S:D193	S:S:N192	1.35	No	Yes	0	1	1
1229	P:P:D97	P:P:N101	1.35	No	No	0	5	4
1230	S:S:A100	S:S:Y103	1.33	No	No	0	5	3
1231	S:S:A180	S:S:Y184	1.33	No	No	0	1	5
1232	S:S:D181	S:S:D182	1.33	No	No	0	2	6
1233	C:C:D181	C:C:D182	1.33	No	No	0	2	6
1234	P:P:A100	P:P:Y103	1.33	No	No	0	5	3
1235	R:R:E275	S:S:N35	1.31	No	Yes	0	3	3
1236	S:S:E275	S:S:N278	1.31	No	No	0	3	3
1237	C:C:F199	C:C:V198	1.31	Yes	No	0	5	3
1238	P:P:V177	P:P:Y184	1.26	No	No	0	4	5
1239	R:R:F107	R:R:L108	1.22	No	No	0	1	5
1240	C:C:F107	C:C:L108	1.22	No	No	0	1	5
1241	P:P:F107	P:P:L108	1.22	No	No	0	1	5
1242	R:R:L301	R:R:R77	1.21	No	Yes	0	7	8
1243	C:C:R235	R:R:L305	1.21	No	No	0	5	6
1244	C:C:N143	C:C:R146	1.21	No	No	0	5	5
1245	C:C:L226	C:C:R235	1.21	No	No	0	8	5
1246	C:C:L238	C:C:R235	1.21	No	No	0	5	5
1247	P:P:N278	P:P:R30	1.21	No	No	0	3	5
1248	S:S:L132	S:S:Y135	1.17	No	Yes	0	6	8
1249	R:R:N101	R:R:Y184	1.16	No	No	0	4	5
1250	C:C:H281	C:C:R30	1.13	No	No	0	4	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:F29	5.98	4	0	4
2	R:R:N37	5.4175	4	0	3
3	R:R:I44	4.275	4	15	5
4	R:R:Y45	4.2725	4	0	7
5	R:R:I48	6.3475	4	15	7
6	R:R:M63	3.435	4	11	6
7	R:R:Q66	5.41	4	0	4
8	R:R:D74	5.515	4	11	8
9	R:R:Y76	6.29	4	0	7
10	R:R:R77	12.0475	4	11	8
11	R:R:F87	10.015	4	3	7
12	R:R:T90	4.7125	4	3	6
13	R:R:F93	6.5025	4	3	6
14	R:R:W94	4.945	4	0	7
15	R:R:W102	10.518	5	3	9
16	R:R:F104	8.2025	4	0	7
17	R:R:V112	5.2375	4	3	5
18	R:R:H113	5.505	6	3	6
19	R:R:Y116	5.772	5	3	6
20	R:R:Y121	7.4125	4	13	7
21	R:R:R134	2.992	5	7	9
22	R:R:Y135	5.5575	4	18	8
23	R:R:H140	3.8875	4	18	6
24	R:R:R148	5.874	5	7	6
25	R:R:V160	5.596	5	16	7
26	R:R:W161	5.9825	4	16	9
27	R:R:D171	8.9525	4	3	4
28	R:R:I185	5.87	4	0	3
29	R:R:R188	9.84	5	3	5
30	R:R:Y190	7.43143	7	3	4
31	R:R:W195	5.79	5	3	5
32	R:R:F199	7.655	4	3	5
33	R:R:Q200	6.4625	4	0	5
34	R:R:H203	3.72	4	0	4
35	R:R:C218	2.6925	4	0	6
36	R:R:Y219	5.132	5	7	8
37	R:R:I222	5.135	4	7	8
38	R:R:L238	4.255	4	7	5
39	R:R:F248	8.14	5	3	9
40	R:R:W252	7.04714	7	3	9
41	R:R:Y256	5.31	5	0	8
42	R:R:I259	6.5725	4	0	5
43	R:R:D262	7.1475	4	8	5
44	R:R:I265	5.545	4	8	3
45	R:R:I270	4.3725	4	0	5
46	R:R:F276	5.6225	4	8	1
47	R:R:V280	3.94	4	8	5
48	R:R:W283	9.0875	4	0	6
49	R:R:E288	8.5325	4	3	5
50	R:R:F292	7.666	5	3	7
51	R:R:F293	6.35	4	15	5
52	R:R:N298	7.73	5	11	9
53	R:R:Y302	11.658	5	11	9
54	S:S:N35	5.86	4	8	3
55	S:S:K38	5.7725	4	8	4
56	S:S:I39	5.3525	4	0	5
57	S:S:Y45	4.556	5	0	7
58	S:S:N56	4.6875	4	0	9
59	S:S:M72	4.8075	4	9	6
60	S:S:Y76	5.346	5	9	7
61	S:S:R77	9.7475	4	0	8
62	S:S:S81	5.015	4	0	9
63	S:S:D84	6.466	5	1	9
64	S:S:F87	8.64	5	1	7
65	S:S:T90	4.3875	4	1	6
66	S:S:L91	3.3925	4	1	8
67	S:S:F93	6.204	5	1	6
68	S:S:W94	3.91	6	1	7
69	S:S:W102	8.27667	6	1	9
70	S:S:V112	4.95	4	1	5
71	S:S:Y116	5.096	5	1	6
72	S:S:Y121	6.94	4	1	7
73	S:S:S122	4.87	4	20	7
74	S:S:F129	3.725	4	9	5
75	S:S:S131	5.9775	4	6	9
76	S:S:Y135	5.17857	7	6	8
77	S:S:H140	5.0425	4	6	6
78	S:S:R148	7.1375	4	9	6
79	S:S:V160	5.39	4	20	7
80	S:S:W161	5.7175	4	20	9
81	S:S:T168	3.3425	4	21	6
82	S:S:D171	8.4325	4	0	4
83	S:S:R188	8.9625	4	0	5
84	S:S:Y190	9.245	4	0	4
85	S:S:N192	3.88	4	0	1
86	S:S:H203	6.95	5	1	4
87	S:S:Y219	6.628	5	6	8
88	S:S:I222	3.8	4	6	8
89	S:S:F248	7.06167	6	1	9
90	S:S:W252	6.57571	7	1	9
91	S:S:Y255	7.846	5	1	7
92	S:S:Y256	5.66143	7	1	8
93	S:S:I259	5.25667	6	1	5
94	S:S:I261	3.1175	4	1	5
95	S:S:V280	3.766	5	1	5
96	S:S:W283	7.88	4	1	6
97	S:S:I284	4.155	4	1	4
98	S:S:F292	7.238	5	1	7
99	S:S:H294	7.06333	6	1	9
100	S:S:N298	4.8775	4	0	9
101	S:S:P299	3.935	4	0	9
102	C:C:N37	5.275	4	0	3
103	C:C:Y45	4.9375	4	0	7
104	C:C:F49	4.5725	4	0	6
105	C:C:N56	5.095	4	0	9
106	C:C:V62	3.0675	4	22	7
107	C:C:M72	3.845	4	0	6
108	C:C:Y76	5.358	5	23	7
109	C:C:R77	7.07167	6	0	8
110	C:C:L80	4.155	4	0	9
111	C:C:D84	5.868	5	2	9
112	C:C:F87	8.22	5	2	7
113	C:C:L91	3.3925	4	2	8
114	C:C:F93	6.225	4	2	6
115	C:C:W94	5.356	5	2	7
116	C:C:W102	8.675	6	2	9
117	C:C:F104	9.8325	4	2	7
118	C:C:V112	4.84	4	2	5
119	C:C:H113	5.112	5	2	6
120	C:C:Y116	5.625	4	2	6
121	C:C:Y121	5.618	5	0	7
122	C:C:S122	4.022	5	12	7
123	C:C:I126	4.5	4	12	7
124	C:C:Y135	6.1425	4	24	8
125	C:C:V160	4.3925	4	12	7
126	C:C:W161	4.8475	4	12	9
127	C:C:D171	6.1975	4	2	4
128	C:C:F174	4.85	5	2	4
129	C:C:C186	6.25	4	2	9
130	C:C:R188	7.36	4	2	5
131	C:C:Y190	7.804	5	2	4
132	C:C:F199	4.38	4	2	5
133	C:C:F248	6.81833	6	2	9
134	C:C:W252	7.11333	6	2	9
135	C:C:Y255	7.095	4	2	7
136	C:C:Y256	6.00857	7	2	8
137	C:C:I259	5.546	5	2	5
138	C:C:I261	3.5025	4	0	5
139	C:C:D262	4.82	5	25	5
140	C:C:W283	7.856	5	0	6
141	C:C:F292	9.1325	4	2	7
142	C:C:H294	7.98	6	2	9
143	C:C:N298	5.3725	4	0	9
144	C:C:Y302	8.87	4	0	9
145	P:P:I39	4.608	5	1	5
146	P:P:Y45	4.528	5	5	7
147	P:P:N56	4.675	4	0	9
148	P:P:M63	5.3475	4	26	6
149	P:P:M72	3.755	4	27	6
150	P:P:Y76	5.0775	4	0	7
151	P:P:R77	5.852	5	0	8
152	P:P:D84	6.4325	4	0	9
153	P:P:F87	8.634	5	5	7
154	P:P:F93	4.656	5	4	6
155	P:P:W94	4.58	5	0	7
156	P:P:W102	9.23667	6	4	9
157	P:P:V112	5.455	4	4	5
158	P:P:H113	4.172	5	4	6
159	P:P:Y116	5.5625	4	5	6
160	P:P:Y121	6.365	4	0	7
161	P:P:S122	4.516	5	14	7
162	P:P:I126	4.5	4	14	7
163	P:P:Y135	5.9625	4	0	8
164	P:P:V139	5.1825	4	0	7
165	P:P:V160	4.3925	4	14	7
166	P:P:D171	7.9325	4	4	4
167	P:P:F174	5.69	4	4	4
168	P:P:R188	7.98	4	4	5
169	P:P:Y190	7.962	5	4	4
170	P:P:W195	5.95	4	4	5
171	P:P:F199	7.205	4	4	5
172	P:P:H203	7.42	4	5	4
173	P:P:F248	6.64333	6	5	9
174	P:P:W252	7.89571	7	5	9
175	P:P:Y255	6.88	6	5	7
176	P:P:Y256	5.92	6	5	8
177	P:P:I259	7.315	4	0	5
178	P:P:I261	3.8725	4	10	5
179	P:P:I270	4.2075	4	0	5
180	P:P:F276	4.37	4	0	1
181	P:P:W283	7.394	5	10	6
182	P:P:F292	8.582	5	5	7
183	P:P:H294	8.368	5	5	9
184	P:P:P299	4.3425	4	0	9
185	L:L:F312	8.132	5	3	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:F314	L:L:K313	15.315	3.72	No	No	0	4	5
2	L:L:F312	R:R:Q200	39.5923	9.37	Yes	Yes	0	5	5
3	R:R:D262	R:R:Q200	41.0084	7.83	Yes	Yes	0	5	5
4	L:L:F312	R:R:R188	38.7038	17.1	Yes	Yes	3	5	5
5	R:R:H113	R:R:R188	34.5075	9.03	Yes	Yes	3	6	5
6	R:R:C109	R:R:H113	17.6047	2.95	No	Yes	3	9	6
7	R:R:C109	R:R:W102	17.6163	5.22	No	Yes	3	9	9
8	R:R:F104	R:R:W102	48.7771	14.03	Yes	Yes	0	7	9
9	R:R:F104	R:R:V96	56.2584	6.55	Yes	No	0	7	5
10	R:R:A100	R:R:V96	56.1588	1.7	No	No	0	5	5
11	R:R:A100	R:R:V99	56.0951	1.7	No	No	0	5	4
12	C:C:I261	R:R:V99	56.0366	4.61	Yes	No	0	5	4
13	C:C:I261	C:C:V280	76.5737	3.07	Yes	No	0	5	5
14	R:R:C186	R:R:H113	17.6047	2.95	No	Yes	3	9	6
15	R:R:C186	R:R:W102	17.6163	18.28	No	Yes	3	9	9
16	R:R:R188	R:R:Y116	13.0853	3.09	Yes	Yes	3	5	6
17	R:R:F87	R:R:Y116	19.7874	8.25	Yes	Yes	3	7	6
18	R:R:F87	R:R:L91	42.0412	3.65	Yes	No	0	7	8
19	R:R:I48	R:R:L91	41.3733	2.85	Yes	No	0	7	8
20	R:R:I44	R:R:I48	22.711	2.94	Yes	Yes	15	5	7
21	R:R:F40	R:R:I44	23.1981	7.54	No	Yes	0	5	5
22	R:R:F36	R:R:F40	22.9894	10.72	No	No	0	4	5
23	C:C:W283	R:R:F36	22.7842	3.01	Yes	No	0	6	4
24	C:C:I261	R:R:I39	21.1	2.94	Yes	No	0	5	5
25	C:C:W283	R:R:I39	21.1616	15.27	Yes	No	0	6	5
26	R:R:I265	R:R:V280	92.7435	3.07	Yes	Yes	8	3	5
27	R:R:I284	R:R:V280	60.0963	3.07	No	Yes	0	4	5
28	R:R:I259	R:R:I284	61.0005	5.89	Yes	No	0	5	4
29	R:R:I259	R:R:Y255	40.9873	10.88	Yes	No	0	5	7
30	R:R:W252	R:R:Y255	19.214	7.72	Yes	No	0	9	7
31	R:R:F292	R:R:W252	37.8608	3.01	Yes	Yes	3	7	9
32	R:R:F292	R:R:Y45	20.7455	6.19	Yes	Yes	0	7	7
33	R:R:I259	R:R:Y256	22.1555	3.63	Yes	Yes	0	5	8
34	R:R:W252	R:R:Y256	22.7305	3.86	Yes	Yes	0	9	8
35	R:R:E288	R:R:Y255	22.6391	14.59	Yes	No	0	5	7
36	R:R:E288	R:R:F292	15.5802	5.83	Yes	Yes	3	5	7
37	R:R:W94	R:R:Y45	20.0496	2.89	Yes	Yes	0	7	7
38	R:R:C295	R:R:I48	32.1561	3.27	No	Yes	0	9	7
39	R:R:N298	R:R:S81	17.0023	5.96	Yes	No	0	9	9
40	R:R:N56	R:R:S81	28.6318	5.96	No	No	0	9	9
41	R:R:D84	R:R:N56	29.9549	12.12	No	No	0	9	9
42	R:R:C295	R:R:D84	30.3955	7.78	No	No	0	9	9
43	R:R:M63	R:R:Y302	14.3461	4.79	Yes	Yes	11	6	9
44	R:R:V59	R:R:Y302	10.7447	6.31	No	Yes	0	8	9
45	R:R:S81	R:R:V59	11.1892	6.46	No	No	0	9	8
46	R:R:N298	R:R:Y302	10.7555	9.3	Yes	Yes	11	9	9
47	R:R:A83	R:R:S122	13.8054	3.42	No	No	0	8	7
48	R:R:A83	R:R:N119	14.4882	3.13	No	No	0	8	8
49	R:R:F87	R:R:N119	15.172	12.08	Yes	No	0	7	8
50	R:R:I245	R:R:Y219	12.5145	3.63	No	Yes	0	7	8
51	R:R:I245	R:R:L127	13.0343	2.85	No	No	0	7	8
52	R:R:F248	R:R:L127	15.4227	8.53	Yes	No	0	9	8
53	R:R:F248	R:R:W252	29.271	10.02	Yes	Yes	3	9	9
54	R:R:V112	R:R:W94	14.2039	6.13	Yes	Yes	0	5	7
55	L:L:F314	R:R:I185	13.4033	12.56	No	Yes	0	4	3
56	R:R:F248	R:R:F249	12.6618	5.36	Yes	No	0	9	4
57	R:R:F249	R:R:I215	11.4666	3.77	No	No	0	4	7
58	R:R:I215	R:R:S131	10.94	6.19	No	No	0	7	9
59	R:R:C218	R:R:S131	10.3339	3.44	Yes	No	0	6	9
60	R:R:I265	R:R:I270	96.2721	7.36	Yes	Yes	0	3	5
61	R:R:I270	S:S:V99	100	3.07	Yes	No	0	5	4
62	S:S:P42	S:S:V99	97.3254	3.53	No	No	19	5	4
63	S:S:A98	S:S:P42	99.1521	5.61	No	No	0	5	5
64	S:S:A98	S:S:L41	99.0913	3.15	No	No	0	5	6
65	S:S:L41	S:S:Y45	98.9842	7.03	No	Yes	0	6	7
66	S:S:W94	S:S:Y45	22.7091	2.89	Yes	Yes	0	7	7
67	S:S:F87	S:S:N119	13.8317	13.29	Yes	No	1	7	8
68	S:S:D84	S:S:N119	13.2509	6.73	Yes	No	1	9	8
69	S:S:F292	S:S:Y45	78.7264	6.19	Yes	Yes	0	7	7
70	S:S:F292	S:S:W252	53.7985	4.01	Yes	Yes	1	7	9
71	S:S:H294	S:S:W252	17.5559	11.64	Yes	Yes	1	9	9
72	S:S:D84	S:S:H294	16.3753	5.04	Yes	Yes	1	9	9
73	S:S:D84	S:S:L80	21.6493	4.07	Yes	No	0	9	9
74	S:S:W252	S:S:Y255	28.6275	7.72	Yes	Yes	1	9	7
75	S:S:I259	S:S:Y255	52.1583	10.88	Yes	Yes	1	5	7
76	S:S:I259	S:S:I284	83.3338	4.42	Yes	Yes	1	5	4
77	S:S:I284	S:S:V280	81.8071	3.07	Yes	Yes	1	4	5
78	S:S:E288	S:S:F292	20.1681	5.83	No	Yes	1	5	7
79	S:S:E288	S:S:Y255	25.3979	11.22	No	Yes	1	5	7
80	S:S:W252	S:S:Y256	29.455	2.89	Yes	Yes	1	9	8
81	S:S:I259	S:S:Y256	28.0959	3.63	Yes	Yes	1	5	8
82	S:S:I126	S:S:L80	15.6159	4.28	No	No	0	7	9
83	S:S:W94	S:S:Y116	10.6911	2.89	Yes	Yes	1	7	6
84	S:S:H113	S:S:W94	15.3718	6.35	No	Yes	0	6	7
85	S:S:D171	S:S:H113	12.6968	7.56	Yes	No	0	4	6
86	S:S:F248	S:S:W252	11.564	10.02	Yes	Yes	1	9	9
87	S:S:F248	S:S:L127	10.4057	6.09	Yes	No	0	9	8
88	P:P:N56	P:P:P299	10.5758	3.26	Yes	Yes	0	9	9
89	P:P:D84	P:P:N56	21.1202	6.73	Yes	Yes	0	9	9
90	P:P:D84	P:P:N119	29.4912	4.04	Yes	No	0	9	8
91	P:P:F87	P:P:N119	30.1	13.29	Yes	No	0	7	8
92	P:P:F87	P:P:L91	68.4048	3.65	Yes	No	0	7	8
93	P:P:I48	P:P:L91	69.1584	2.85	No	No	0	7	8
94	P:P:I44	P:P:I48	71.2615	2.94	No	No	0	5	7
95	P:P:F40	P:P:I44	71.7377	7.54	No	No	0	5	5
96	P:P:F36	P:P:F40	71.9777	9.65	No	No	0	4	5
97	P:P:F36	P:P:I39	71.6962	3.77	No	Yes	1	4	5
98	P:P:I39	S:S:V280	74.2833	3.07	Yes	Yes	1	5	5
99	P:P:R77	P:P:Y302	10.5988	14.4	Yes	No	0	8	9
100	P:P:N298	P:P:R77	14.375	3.62	No	Yes	0	9	8
101	C:C:F292	C:C:Y45	44.5093	7.22	Yes	Yes	0	7	7
102	C:C:E288	C:C:F292	20.9364	8.16	No	Yes	2	5	7
103	C:C:E288	C:C:Y255	25.4021	8.98	No	Yes	2	5	7
104	C:C:I259	C:C:Y255	45.8854	9.67	Yes	Yes	2	5	7
105	C:C:I259	C:C:I284	75.4827	4.42	Yes	No	0	5	4
106	C:C:D262	C:C:I284	75.5292	4.2	Yes	No	0	5	4
107	C:C:D262	C:C:V280	75.8539	4.38	Yes	No	0	5	5
108	P:P:I261	P:P:V280	43.9829	3.07	Yes	No	0	5	5
109	C:C:P42	P:P:I261	43.9915	3.39	No	Yes	10	5	5
110	C:C:A98	C:C:P42	44.1284	3.74	No	No	0	5	5
111	C:C:A98	C:C:L41	44.1473	3.15	No	No	0	5	6
112	C:C:L41	C:C:Y45	44.1705	5.86	No	Yes	0	6	7
113	P:P:D262	P:P:V280	43.9679	2.92	No	No	0	5	5
114	P:P:D262	P:P:I284	43.9786	4.2	No	No	0	5	4
115	P:P:I259	P:P:I284	43.991	4.42	Yes	No	0	5	4
116	P:P:I259	P:P:Y255	44.0444	12.09	Yes	Yes	0	5	7
117	P:P:Y116	P:P:Y255	29.7627	2.98	Yes	Yes	5	6	7
118	P:P:F87	P:P:Y116	30.4582	7.22	Yes	Yes	5	7	6
119	C:C:F292	C:C:F87	27.8186	13.93	Yes	Yes	2	7	7
120	C:C:H294	C:C:W252	22.7192	11.64	Yes	Yes	2	9	9
121	C:C:W252	C:C:Y255	28.069	6.75	Yes	Yes	2	9	7
122	C:C:W252	C:C:Y256	24.7516	4.82	Yes	Yes	2	9	8
123	C:C:I259	C:C:Y256	29.1123	3.63	Yes	Yes	2	5	8
124	C:C:D84	C:C:H294	21.2857	6.3	Yes	Yes	2	9	9
125	C:C:M63	C:C:Y302	10.4873	7.18	No	Yes	0	6	9
126	C:C:N298	C:C:R77	14.8343	9.64	Yes	Yes	0	9	8
127	C:C:L80	C:C:N298	15.3874	4.12	Yes	Yes	0	9	9
128	C:C:D84	C:C:L80	25.2051	4.07	Yes	Yes	0	9	9
129	C:C:L127	C:C:L80	17.4838	4.15	No	Yes	0	8	9
130	C:C:F248	C:C:L127	26.2791	8.53	Yes	No	0	9	8
131	C:C:F248	C:C:W252	33.0267	11.02	Yes	Yes	2	9	9
132	C:C:I130	C:C:Y76	14.8602	4.84	No	Yes	0	8	7
133	C:C:I126	C:C:I130	15.4045	2.94	Yes	No	0	7	8
134	C:C:I126	C:C:L80	23.0118	4.28	Yes	Yes	0	7	9
135	C:C:F87	C:C:W94	13.268	3.01	Yes	Yes	2	7	7
136	C:C:I245	C:C:L127	12.5403	2.85	No	No	0	7	8
137	C:C:I245	C:C:Y219	11.9827	4.84	No	No	0	7	8
138	C:C:L238	C:C:V242	10.1464	4.47	No	No	0	5	4
139	C:C:V242	C:C:Y219	11.4436	7.57	No	No	0	4	8
140	P:P:F87	P:P:W94	19.9742	4.01	Yes	Yes	0	7	7
141	P:P:I126	P:P:L80	13.6478	4.28	Yes	No	0	7	9
142	P:P:D84	P:P:L80	14.0234	4.07	Yes	No	0	9	9
143	P:P:H294	P:P:N119	11.9572	5.1	Yes	No	0	9	8
144	P:P:I245	P:P:L127	12.3744	5.71	No	No	0	7	8
145	P:P:F248	P:P:L127	12.7579	6.09	Yes	No	0	9	8
146	P:P:I215	P:P:I245	11.9907	4.42	No	No	0	7	7
147	P:P:I215	P:P:S131	10.8383	9.29	No	No	0	7	9
148	L:L:K313	R:R:E288	11.3284	8.1	No	Yes	0	5	5
149	R:R:E288	R:R:Y116	13.3864	5.61	Yes	Yes	3	5	6
150	R:R:F292	R:R:F87	32.837	16.08	Yes	Yes	3	7	7
151	R:R:D262	R:R:V280	37.9186	4.38	Yes	Yes	8	5	5
152	P:P:H294	P:P:W252	11.0448	15.87	Yes	Yes	5	9	9
153	P:P:W252	P:P:Y255	13.9352	7.72	Yes	Yes	5	9	7
154	C:C:D84	C:C:N119	13.1115	4.04	Yes	No	2	9	8
155	C:C:F87	C:C:N119	17.3617	13.29	Yes	No	2	7	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:E26	R:R:F29	3.5	0	No	Yes	2	4	1	1
L:L:V303	R:R:C28	5.12	0	No	No	8	9	0	1
R:R:C274	R:R:F29	6.98	0	No	Yes	5	4	2	1
R:R:E277	R:R:F29	8.16	0	No	Yes	2	4	2	1
L:L:S316	R:R:F29	5.28	0	No	Yes	5	4	0	1
L:L:F314	R:R:E31	3.5	0	No	No	4	5	0	1
R:R:D171	R:R:H113	6.3	3	Yes	Yes	4	6	2	2
R:R:H113	R:R:R188	9.03	3	Yes	Yes	6	5	2	1
R:R:L120	R:R:Y116	4.69	0	No	Yes	7	6	2	2
R:R:R188	R:R:Y116	3.09	3	Yes	Yes	5	6	1	2
R:R:E288	R:R:Y116	5.61	3	Yes	Yes	5	6	1	2
R:R:F292	R:R:Y116	7.22	3	Yes	Yes	7	6	2	2
R:R:H203	R:R:L120	3.86	0	Yes	No	4	7	1	2
R:R:H203	R:R:Y121	4.36	0	Yes	Yes	4	7	1	2
R:R:D171	R:R:R188	10.72	3	Yes	Yes	4	5	2	1
R:R:F174	R:R:Y190	6.19	3	No	Yes	4	4	2	1
R:R:F174	R:R:F199	4.29	3	No	Yes	4	5	2	2
R:R:I185	R:R:S178	4.64	0	Yes	No	3	1	1	1
L:L:M309	R:R:S178	6.13	0	No	No	7	1	0	1
R:R:F189	R:R:I185	3.77	0	No	Yes	3	3	2	1
L:L:F314	R:R:I185	12.56	0	No	Yes	4	3	0	1
L:L:F312	R:R:D187	3.58	3	Yes	No	5	3	0	1
L:L:K313	R:R:D187	6.91	0	No	No	5	3	0	1
R:R:R188	R:R:Y190	9.26	3	Yes	Yes	5	4	1	1
L:L:F312	R:R:R188	17.1	3	Yes	Yes	5	5	0	1
R:R:W195	R:R:Y190	3.86	3	Yes	Yes	5	4	2	1
R:R:V196	R:R:Y190	5.05	0	No	Yes	4	4	2	1
R:R:F199	R:R:Y190	17.54	3	Yes	Yes	5	4	2	1
L:L:G311	R:R:Y190	2.9	0	No	Yes	9	4	0	1
L:L:F312	R:R:Y190	7.22	3	Yes	Yes	5	4	0	1
L:L:S310	R:R:D193	2.94	0	No	No	8	1	0	1
L:L:K317	R:R:D193	8.3	0	No	No	8	1	0	1
R:R:F199	R:R:W195	3.01	3	Yes	Yes	5	5	2	2
R:R:Q200	R:R:V196	2.87	0	Yes	No	5	4	1	2
R:R:L266	R:R:V196	2.98	0	No	No	3	4	1	2
R:R:S263	R:R:V197	4.85	0	No	No	5	3	2	2
R:R:L266	R:R:V197	2.98	0	No	No	3	3	1	2
R:R:D262	R:R:Q200	7.83	8	Yes	Yes	5	5	1	1
R:R:Q200	R:R:S263	5.78	0	Yes	No	5	5	1	2
L:L:F312	R:R:Q200	9.37	3	Yes	Yes	5	5	0	1
R:R:H203	R:R:Y256	3.27	0	Yes	Yes	4	8	1	2
L:L:F312	R:R:H203	3.39	3	Yes	Yes	5	4	0	1
R:R:E288	R:R:Y255	14.59	3	Yes	No	5	7	1	2
R:R:D262	R:R:V280	4.38	8	Yes	Yes	5	5	1	2
R:R:D262	R:R:H281	6.3	8	Yes	No	5	4	1	1
L:L:H315	R:R:D262	10.08	8	No	Yes	5	5	0	1
L:L:H315	R:R:L266	9	8	No	No	5	3	0	1
L:L:K317	R:R:E268	6.75	0	No	No	8	2	0	1
R:R:E277	R:R:H281	7.39	0	No	No	2	4	2	1
L:L:H315	R:R:H281	13.14	8	No	No	5	4	0	1
R:R:E288	R:R:F292	5.83	3	Yes	Yes	5	7	1	2
L:L:K313	R:R:E288	8.1	0	No	Yes	5	5	0	1
R:R:C28	R:R:R30	2.79	0	No	No	9	5	1	2
R:R:I185	R:R:R183	2.51	0	Yes	No	3	3	1	2
R:R:C28	R:R:P27	1.88	0	No	No	9	5	1	2
R:R:A180	R:R:S178	1.71	0	No	No	1	1	2	1
L:L:V319	R:R:E26	1.43	0	No	No	1	2	0	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	9MEN_poly
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	2.85
Number of Linked Nodes	1074
Number of Links	1250
Number of Hubs	185
Number of Links mediated by Hubs	645
Number of Communities	27
Number of Nodes involved in Communities	218
Number of Links involved in Communities	300

Path Summary
Number Of Nodes in MetaPath	156
Number Of Links MetaPath	155
Number of Shortest Paths	2605374
Length Of Smallest Path	3
Average Path Length	27.8578
Length of Longest Path	52
Minimum Path Strength	1.21
Average Path Strength	5.76742
Maximum Path Strength	19.875
Minimum Path Correlation	0.7
Average Path Correlation	0.988955
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	2.32558
Average % Of Corr. Nodes	44.1464
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	51.6111
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• molecular transducer activity • coreceptor activity • signaling receptor activity • cytoskeletal protein binding • myosin light chain binding • protein binding • binding • myosin binding • C-C chemokine binding • chemokine binding • cytokine binding • G protein-coupled chemoattractant receptor activity • C-X-C motif chemokine 12 receptor activity • C-X-C chemokine receptor activity • chemokine receptor activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • cytokine receptor activity • immune receptor activity • ubiquitin protein ligase binding • ubiquitin-like protein ligase binding • enzyme binding • virus receptor activity • exogenous protein binding • C-C chemokine receptor activity • ubiquitin binding • ubiquitin-like protein binding • actin binding • developmental process • multicellular organism development • multicellular organismal process • head development • central nervous system development • anatomical structure development • animal organ development • brain development • nervous system development • system development • regulation of biological process • cell adhesion • regulation of cellular process • regulation of cell adhesion
Gene Ontology	Biological Process	• developmental process • multicellular organism development • multicellular organismal process • head development • central nervous system development • anatomical structure development • animal organ development • brain development • nervous system development • system development • regulation of biological process • cell adhesion • regulation of cellular process • regulation of cell adhesion • biological regulation • cellular process • apoptotic process • cell death • programmed cell death • membrane organization • cellular component organization • myelination • myelin maintenance • axon ensheathment • ensheathment of neurons • plasma membrane organization • cellular component organization or biogenesis • endomembrane system organization • cell chemotaxis • cellular response to stimulus • chemotaxis • dendritic cell chemotaxis • response to stimulus • response to external stimulus • leukocyte migration • dendritic cell migration • cellular response to chemical stimulus • taxis • immune system process • response to chemical • mononuclear cell migration • cell migration • cell motility • leukocyte chemotaxis • locomotion • response to decreased oxygen levels • response to hypoxia • response to stress • response to oxygen levels • response to abiotic stimulus • positive regulation of cytosolic calcium ion concentration • regulation of biological quality • neurogenesis • cellular developmental process • cell differentiation • immune response • cell surface receptor signaling pathway • chemokine (C-X-C motif) ligand 12 signaling pathway • signaling • CXCL12-activated CXCR4 signaling pathway • response to cytokine • response to chemokine • cytokine-mediated signaling pathway • cellular response to chemokine • chemokine-mediated signaling pathway • cell communication • response to peptide • G protein-coupled receptor signaling pathway • cellular response to cytokine stimulus • signal transduction • C-X-C chemokine receptor CXCR4 signaling pathway • intracellular signal transduction • calcium-mediated signaling • intracellular signaling cassette • regulation of multicellular organismal development • regulation of developmental process • positive regulation of biological process • vasculature development • regulation of vasculature development • circulatory system development • positive regulation of developmental process • positive regulation of vasculature development • positive regulation of multicellular organismal process • regulation of multicellular organismal process • positive regulation of cell communication • positive regulation of signal transduction • regulation of signal transduction • positive regulation of macrophage migration inhibitory factor signaling pathway • positive regulation of response to cytokine stimulus • positive regulation of response to stimulus • macrophage migration inhibitory factor signaling pathway • positive regulation of cellular process • regulation of signaling • regulation of macrophage migration inhibitory factor signaling pathway • regulation of cytokine-mediated signaling pathway • regulation of response to cytokine stimulus • regulation of response to stimulus • regulation of cell communication • positive regulation of cytokine-mediated signaling pathway • positive regulation of signaling • homeostatic process • adaptive thermogenesis • multicellular organismal-level homeostasis • regulation of cold-induced thermogenesis • cold-induced thermogenesis • temperature homeostasis • positive regulation of cold-induced thermogenesis • positive regulation of locomotion • regulation of cell motility • positive regulation of cell migration • regulation of locomotion • positive regulation of cell motility • regulation of cell migration • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • biological process involved in interspecies interaction between organisms • response to other organism • response to external biotic stimulus • response to virus • response to biotic stimulus • defense response • inflammatory response • positive regulation of nervous system development • cell development • regulation of neurogenesis • regulation of cell differentiation • regulation of gliogenesis • positive regulation of gliogenesis • regulation of cell development • regulation of nervous system development • gliogenesis • positive regulation of cell differentiation • positive regulation of neurogenesis • positive regulation of oligodendrocyte differentiation • positive regulation of cell development • regulation of glial cell differentiation • positive regulation of glial cell differentiation • oligodendrocyte differentiation • glial cell differentiation • regulation of oligodendrocyte differentiation • cell periphery • cellular anatomical structure • cell surface • membrane • plasma membrane • external side of plasma membrane • side of membrane • extracellular exosome • membrane-bounded organelle • extracellular vesicle • extracellular organelle • extracellular region • organelle • extracellular space
Gene Ontology	Cellular Component	• cell periphery • cellular anatomical structure • cell surface • membrane • plasma membrane • external side of plasma membrane • side of membrane • extracellular exosome • membrane-bounded organelle • extracellular vesicle • extracellular organelle • extracellular region • organelle • extracellular space • vesicle • extracellular membrane-bounded organelle • cell leading edge • intracellular anatomical structure • cytoplasm • anchoring junction • cell junction • intracellular organelle • lytic vacuole • vacuole • intracellular membrane-bounded organelle • lysosome • protein-containing complex • cytoplasmic vesicle • intracellular vesicle • early endosome • endosome • endomembrane system • late endosome • structural molecule activity • viral process • fusion of virus membrane with host endosome membrane • membrane fusion involved in viral entry into host cell • virion attachment to host cell • biological process involved in interspecies interaction between organisms • adhesion of symbiont to host cell • viral life cycle • adhesion of symbiont to host • biological process involved in interaction with host • biological process involved in symbiotic interaction • symbiont-mediated perturbation of host defense response • symbiont-mediated perturbation of host process • symbiont-mediated-mediated suppression of host tetherin activity • modulation of process of another organism • import into cell • receptor-mediated endocytosis of virus by host cell • transport • establishment of localization • vesicle-mediated transport • localization • symbiont entry into host cell • clathrin-dependent endocytosis • symbiont entry into host • cellular process • clathrin-dependent endocytosis of virus by host cell • receptor-mediated endocytosis • endocytosis • endocytosis involved in viral entry into host cell • symbiont-mediated suppression of host immune response • symbiont-mediated suppression of host innate immune response • symbiont-mediated perturbation of host immune response • symbiont-mediated perturbation of host innate immune response • virion component • virion membrane • host intracellular membrane-bounded organelle • host cellular component • host intracellular part • host cell membrane • other organism part • host cell cytoplasm part • host intracellular organelle • host cell endosome membrane • host cell cytoplasm • host cell part • host cell endosome • host intracellular region • viral membrane • viral envelope • host cell plasma membrane
SCOP2	Domain Identifier	• G protein-coupled receptor-like
SCOP2	Family Identifier	• G protein-coupled receptor-like
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P61073
Sequence	>9MEN_poly_Chain_R E P C F R E E N A N F N K I F L P T I Y S I I F L T G I V G N G L V I L V M G Y Q K K L R S M T D K Y R L H L S V A D L L F V I T L P F W A V D A V A N W Y F G N F L C K A V H V I Y T V N L Y S S V L I L A F I S L D R Y L A I V H A T N S Q R P R K L L A E K V V Y V G V W I P A L L L T I P D F I F A N V S E A D D R Y I C D R F Y P N D L W V V V F Q F Q H I M V G L I L P G I V I L S C Y C I I I S K L S H S K G H Q K R K A L K T T V I L I L A F F A C W L P Y Y I G I S I D S F I L L E I I K Q G C E F E N T V H K W I S I T E A L A F F H C C L N P I L Y A F L G Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	3ODU	A	Protein	Chemokine	CXCR4	Homo sapiens	IT1t	-	-	2.5	2010-10-27	doi.org/10.1126/science.1194396
	3OE0	A	Protein	Chemokine	CXCR4	Homo sapiens	CVX15	-	-	2.9	2010-10-27	doi.org/10.1126/science.1194396
	3OE6	A	Protein	Chemokine	CXCR4	Homo sapiens	IT1t	-	-	3.2	2010-10-27	doi.org/10.1126/science.1194396
	3OE8	A	Protein	Chemokine	CXCR4	Homo sapiens	IT1t	-	-	3.1	2010-10-27	doi.org/10.1126/science.1194396
	3OE9	A	Protein	Chemokine	CXCR4	Homo sapiens	IT1t	-	-	3.1	2010-10-27	doi.org/10.1126/science.1194396
	4RWS	A	Protein	Chemokine	CXCR4	Homo sapiens	vMIP-II	-	-	3.1	2015-02-11	doi.org/10.1126/science.1261064
	8K3Z	A	Protein	Chemokine	CXCR4	Homo sapiens	CXCL12	-	Gi1/β1/γ1	2.81	2024-07-17	doi.org/10.1016/j.celrep.2024.114578
	8K3Z (No Gprot)	A	Protein	Chemokine	CXCR4	Homo sapiens	CXCL12	-		2.81	2024-07-17	doi.org/10.1016/j.celrep.2024.114578
	8ZPL	A	Protein	Chemokine	CXCR4	Homo sapiens	HF51116	-	-	3.01	2025-02-26	doi.org/10.1073/pnas.2425795122
	8ZPM	A	Protein	Chemokine	CXCR4	Homo sapiens	AMD070	-	-	3.2	2025-02-26	doi.org/10.1073/pnas.2425795122
	8ZPN	A	Protein	Chemokine	CXCR4	Homo sapiens	AMD3100	-	-	3.31	2025-02-26	doi.org/10.1073/pnas.2425795122
	8YU7	A	Protein	Chemokine	CXCR4	Homo sapiens	-	-	-	3.01	2025-03-05	doi.org/10.1016/j.celrep.2025.115255
	9MDU	A	Protein	Chemokine	CXCR4	Homo sapiens	-	-	-	2.9	2025-09-10	To be published
	9ME1	A	Protein	Chemokine	CXCR4	Homo sapiens	CXCL12	-	-	3.37	2025-09-10	To be published
	9MEJ	A	Protein	Chemokine	CXCR4	Homo sapiens	Gp120	-	-	3.99	2025-09-10	To be published
	9MEN	A	Protein	Chemokine	CXCR4	Homo sapiens	Gp120 (V3 loop)	-	-	3.57	2025-09-10	To be published
	9MET	A	Protein	Chemokine	CXCR4	Homo sapiens	Gp120; CD4	-	-	5.65	2025-09-10	To be published
	9MEU	A	Protein	Chemokine	CXCR4	Homo sapiens	CXCL12	-	-	3.46	2025-09-10	To be published
	8U4N	A	Protein	Chemokine	CXCR4	Homo sapiens	-	-	Gi1/β1/γ2	2.72	2024-03-13	doi.org/10.1101/2024.02.09.579708
	8U4N (No Gprot)	A	Protein	Chemokine	CXCR4	Homo sapiens	-	-		2.72	2024-03-13	doi.org/10.1101/2024.02.09.579708
	8U4O	A	Protein	Chemokine	CXCR4	Homo sapiens	CXCL12	-	Gi1/β1/γ2	3.29	2024-03-13	doi.org/10.1101/2024.02.09.579708
	8U4O (No Gprot)	A	Protein	Chemokine	CXCR4	Homo sapiens	CXCL12	-		3.29	2024-03-13	doi.org/10.1101/2024.02.09.579708
	8U4P	A	Protein	Chemokine	CXCR4	Homo sapiens	AMD3100	-	Gi1/β1/γ2	3.15	2024-03-13	doi.org/10.1101/2024.02.09.579708
	8U4P (No Gprot)	A	Protein	Chemokine	CXCR4	Homo sapiens	AMD3100	-		3.15	2024-03-13	doi.org/10.1101/2024.02.09.579708
	8U4Q	A	Protein	Chemokine	CXCR4	Homo sapiens	REGN7663-Fab	-	Gi1/β1/γ2	3.36	2024-03-13	doi.org/10.1101/2024.02.09.579708
	8U4Q (No Gprot)	A	Protein	Chemokine	CXCR4	Homo sapiens	REGN7663-Fab	-		3.36	2024-03-13	doi.org/10.1101/2024.02.09.579708
	8U4R	A	Protein	Chemokine	CXCR4	Homo sapiens	REGN7663-Fab	-	-	3.1	2024-03-13	doi.org/10.1101/2024.02.09.579708
	8U4S	A	Protein	Chemokine	CXCR4	Homo sapiens	REGN7663-Fab	-	-	3.35	2024-03-13	doi.org/10.1038/s41594-024-01397-1
	8U4T	A	Protein	Chemokine	CXCR4	Homo sapiens	REGN7663-Fab	-	-	3.38	2024-03-13	doi.org/10.1038/s41594-024-01397-1

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