psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	S:S:E26	S:S:P27	7.86	No	No	0	2	5
2	S:S:E26	S:S:F29	23.32	No	No	0	2	4
3	S:S:C28	S:S:R30	4.18	No	No	0	9	5
4	M:M:R29	S:S:R30	3.2	Yes	No	0	9	5
5	S:S:E32	S:S:N278	18.4	No	No	0	4	3
6	S:S:N33	S:S:N35	4.09	No	Yes	0	6	3
7	S:S:A34	S:S:K282	3.21	No	No	0	1	2
8	R:R:E275	S:S:N35	3.94	No	Yes	0	3	3
9	R:R:F276	S:S:N35	6.04	No	Yes	0	1	3
10	R:R:T279	S:S:N35	7.31	No	Yes	0	2	3
11	S:S:F36	S:S:I39	3.77	No	No	10	4	5
12	S:S:F36	S:S:F40	7.5	No	No	0	4	5
13	R:R:W283	S:S:F36	3.01	Yes	No	10	6	4
14	S:S:I286	S:S:N37	5.66	No	No	0	6	3
15	R:R:Q272	S:S:K38	5.42	No	No	0	2	4
16	R:R:I261	S:S:I39	2.94	No	No	10	5	5
17	R:R:W283	S:S:I39	11.74	Yes	No	10	6	5
18	S:S:F40	S:S:I44	10.05	No	No	0	5	5
19	S:S:L41	S:S:Y45	3.52	No	Yes	0	6	7
20	S:S:A98	S:S:L41	3.15	No	No	0	5	6
21	S:S:P42	S:S:V99	5.3	No	No	10	5	4
22	R:R:I261	S:S:P42	3.39	No	No	10	5	5
23	R:R:P254	S:S:T43	3.5	No	No	0	9	4
24	R:R:I257	S:S:T43	4.56	No	No	0	6	4
25	R:R:W283	S:S:T43	7.28	Yes	No	0	6	4
26	S:S:I44	S:S:I48	2.94	No	No	0	5	7
27	S:S:W94	S:S:Y45	2.89	Yes	Yes	0	7	7
28	S:S:F292	S:S:Y45	8.25	Yes	Yes	0	7	7
29	R:R:I257	S:S:S46	6.19	No	No	0	6	5
30	R:R:L253	S:S:I47	2.85	No	No	0	5	4
31	S:S:I48	S:S:L91	2.85	No	No	0	7	8
32	S:S:F293	S:S:I48	15.07	Yes	No	0	5	7
33	S:S:F49	S:S:L50	3.65	No	No	0	6	5
34	S:S:F49	S:S:P92	7.22	No	No	0	6	9
35	S:S:C296	S:S:T51	6.76	No	No	0	7	5
36	S:S:G52	S:S:V88	3.68	No	No	0	8	6
37	S:S:I53	S:S:V88	3.07	No	No	0	5	6
38	S:S:G55	S:S:V54	3.68	No	No	0	8	4
39	R:R:L216	S:S:V54	4.47	No	No	0	4	4
40	S:S:G55	S:S:P299	4.06	No	Yes	0	8	9
41	S:S:N56	S:S:S81	4.47	Yes	No	0	9	9
42	S:S:D84	S:S:N56	9.42	No	Yes	0	9	9
43	S:S:N56	S:S:P299	4.89	Yes	Yes	0	9	9
44	R:R:I223	S:S:L58	7.14	No	No	0	4	5
45	S:S:S81	S:S:V59	8.08	No	No	0	9	8
46	S:S:P299	S:S:V59	3.53	Yes	No	0	9	8
47	S:S:I60	S:S:V82	3.07	No	No	0	7	5
48	S:S:I60	S:S:L85	4.28	No	No	0	7	7
49	R:R:S224	S:S:L61	3	No	No	0	4	4
50	S:S:M63	S:S:V62	4.56	No	Yes	16	6	7
51	S:S:K68	S:S:V62	6.07	Yes	Yes	16	6	7
52	R:R:S227	S:S:V62	3.23	No	Yes	0	4	7
53	S:S:K68	S:S:M63	2.88	Yes	No	16	6	6
54	S:S:M63	S:S:Y302	10.78	No	No	0	6	9
55	S:S:G64	S:S:L78	3.42	No	No	0	2	5
56	R:R:S227	S:S:Q66	8.66	No	No	0	4	4
57	R:R:H228	S:S:Q66	12.36	No	No	0	5	4
58	S:S:K67	S:S:L69	4.23	No	No	0	6	6
59	S:S:K68	S:S:R70	6.19	Yes	No	0	6	6
60	R:R:K230	S:S:K68	7.18	No	Yes	0	5	6
61	S:S:K75	S:S:L69	4.23	No	No	0	6	6
62	S:S:S71	S:S:T73	3.2	No	No	0	7	7
63	S:S:D74	S:S:S71	4.42	No	No	0	8	7
64	S:S:M72	S:S:R148	4.96	No	Yes	0	6	6
65	S:S:K149	S:S:M72	4.32	No	No	0	6	6
66	S:S:A152	S:S:M72	3.22	No	No	0	3	6
67	S:S:D74	S:S:Y302	6.9	No	No	0	8	9
68	S:S:E153	S:S:K75	8.1	No	No	0	7	6
69	S:S:F129	S:S:Y76	3.09	No	Yes	18	5	7
70	S:S:I130	S:S:Y76	4.84	No	Yes	0	8	7
71	S:S:D133	S:S:Y76	9.2	No	Yes	0	8	7
72	S:S:L151	S:S:Y76	3.52	No	Yes	18	4	7
73	S:S:A152	S:S:Y76	4	No	Yes	0	3	7
74	S:S:N298	S:S:R77	4.82	Yes	No	0	9	8
75	S:S:R77	S:S:Y302	25.72	No	No	0	8	9
76	S:S:H79	S:S:I126	3.98	No	Yes	0	9	7
77	S:S:H79	S:S:Y157	4.36	No	No	0	9	7
78	S:S:H79	S:S:W161	4.23	No	No	0	9	9
79	S:S:D84	S:S:L80	4.07	No	No	0	9	9
80	S:S:I126	S:S:L80	4.28	Yes	No	0	7	9
81	S:S:L80	S:S:N298	5.49	No	Yes	0	9	9
82	S:S:N298	S:S:S81	4.47	Yes	No	0	9	9
83	S:S:A83	S:S:S122	3.42	No	Yes	0	8	7
84	S:S:C295	S:S:D84	7.78	No	No	0	9	9
85	S:S:F87	S:S:L91	3.65	Yes	No	0	7	8
86	S:S:F87	S:S:Y116	8.25	Yes	Yes	1	7	6
87	S:S:F87	S:S:N119	10.87	Yes	No	0	7	8
88	S:S:F292	S:S:F87	13.93	Yes	Yes	1	7	7
89	S:S:C295	S:S:V88	3.42	No	No	0	9	6
90	S:S:I89	S:S:T90	3.04	No	No	0	4	6
91	S:S:T90	S:S:V112	6.35	No	Yes	0	6	5
92	S:S:I115	S:S:T90	7.6	No	No	0	5	6
93	S:S:F104	S:S:F93	10.72	No	No	0	7	6
94	S:S:F93	S:S:L108	3.65	No	No	0	6	5
95	S:S:F93	S:S:V112	3.93	No	Yes	0	6	5
96	S:S:D97	S:S:W94	3.35	No	Yes	0	5	7
97	S:S:V112	S:S:W94	7.36	Yes	Yes	0	5	7
98	S:S:H113	S:S:W94	6.35	Yes	Yes	1	6	7
99	M:M:K22	S:S:W94	12.76	Yes	Yes	1	9	7
100	S:S:F104	S:S:V96	5.24	No	No	0	7	5
101	S:S:D97	S:S:W102	8.93	No	Yes	0	5	9
102	R:R:I261	S:S:V99	9.22	No	No	10	5	4
103	S:S:N101	S:S:R183	3.62	No	No	0	4	3
104	S:S:F104	S:S:W102	16.04	No	Yes	0	7	9
105	S:S:C109	S:S:W102	3.92	No	Yes	1	9	9
106	S:S:V112	S:S:W102	3.68	Yes	Yes	0	5	9
107	S:S:C186	S:S:W102	15.67	No	Yes	1	9	9
108	S:S:C109	S:S:H113	2.95	No	Yes	1	9	6
109	S:S:C109	S:S:C186	7.28	No	No	1	9	9
110	S:S:K110	S:S:N176	5.6	No	No	0	7	4
111	S:S:D171	S:S:H113	3.78	Yes	Yes	0	4	6
112	S:S:A175	S:S:H113	4.39	No	Yes	0	4	6
113	S:S:C186	S:S:H113	4.42	No	Yes	1	9	6
114	M:M:K22	S:S:H113	7.86	Yes	Yes	1	9	6
115	S:S:T168	S:S:V114	4.76	No	No	0	6	5
116	S:S:D171	S:S:V114	2.92	Yes	No	0	4	5
117	S:S:F172	S:S:V114	3.93	No	No	0	4	5
118	S:S:L120	S:S:Y116	3.52	Yes	Yes	1	7	6
119	S:S:F292	S:S:Y116	8.25	Yes	Yes	1	7	6
120	M:M:K22	S:S:Y116	4.78	Yes	Yes	1	9	6
121	S:S:T117	S:S:T168	3.14	No	No	0	5	6
122	S:S:D171	S:S:T117	11.56	Yes	No	0	4	5
123	M:M:P23	S:S:T117	3.5	No	No	0	9	5
124	S:S:L165	S:S:V118	2.98	No	No	0	3	5
125	S:S:H294	S:S:N119	5.1	Yes	No	0	9	8
126	S:S:H203	S:S:L120	5.14	Yes	Yes	1	4	7
127	S:S:L120	S:S:W252	5.69	Yes	Yes	1	7	9
128	M:M:P23	S:S:L120	3.28	No	Yes	1	9	7
129	S:S:L167	S:S:Y121	12.89	No	Yes	1	5	7
130	S:S:Q202	S:S:Y121	6.76	Yes	Yes	1	3	7
131	S:S:H203	S:S:Y121	5.44	Yes	Yes	1	4	7
132	S:S:V206	S:S:Y121	3.79	No	Yes	1	4	7
133	S:S:S122	S:S:V160	3.23	Yes	Yes	19	7	7
134	S:S:S122	S:S:W161	11.12	Yes	No	19	7	9
135	S:S:F248	S:S:S123	6.61	Yes	No	1	9	9
136	S:S:H294	S:S:S123	5.58	Yes	No	1	9	9
137	S:S:P211	S:S:V124	3.53	No	No	0	9	7
138	S:S:F248	S:S:V124	3.93	Yes	No	0	9	7
139	S:S:L125	S:S:V160	2.98	No	Yes	0	5	7
140	S:S:I126	S:S:I130	2.94	Yes	No	0	7	8
141	S:S:I126	S:S:V160	9.22	Yes	Yes	0	7	7
142	S:S:I245	S:S:L127	2.85	Yes	No	0	7	8
143	S:S:F248	S:S:L127	6.09	Yes	No	0	9	8
144	S:S:F129	S:S:L151	4.87	No	No	18	5	4
145	S:S:F129	S:S:G159	3.01	No	No	0	5	3
146	S:S:I215	S:S:S131	9.29	No	Yes	14	7	9
147	S:S:C218	S:S:S131	3.44	No	Yes	0	6	9
148	S:S:S131	S:S:Y219	10.17	Yes	Yes	14	9	8
149	S:S:I245	S:S:S131	3.1	Yes	Yes	14	7	9
150	S:S:D133	S:S:R148	10.72	No	Yes	0	8	6
151	S:S:A137	S:S:R134	5.53	No	No	17	8	9
152	S:S:R134	S:S:R148	3.2	No	Yes	17	9	6
153	S:S:V139	S:S:Y135	5.05	No	Yes	20	7	8
154	S:S:H140	S:S:Y135	3.27	Yes	Yes	20	6	8
155	S:S:C218	S:S:Y135	4.03	No	Yes	0	6	8
156	S:S:I221	S:S:Y135	6.04	No	Yes	0	4	8
157	S:S:H140	S:S:L136	3.86	Yes	No	0	6	5
158	S:S:L136	S:S:S144	4.5	No	No	0	5	5
159	S:S:A137	S:S:R148	6.91	No	Yes	17	8	6
160	S:S:I138	S:S:I222	7.36	No	No	0	8	8
161	S:S:I138	S:S:K234	2.91	No	No	0	8	7
162	S:S:H140	S:S:V139	11.07	Yes	No	20	6	7
163	S:S:K225	S:S:V139	3.04	No	No	0	4	7
164	S:S:N143	S:S:T142	5.85	No	No	0	5	5
165	S:S:Q145	S:S:R146	8.18	No	No	0	5	5
166	S:S:P147	S:S:R146	2.88	No	No	0	4	5
167	S:S:K149	S:S:R146	8.66	No	No	0	6	5
168	S:S:E153	S:S:K154	5.4	No	No	0	7	3
169	S:S:V156	S:S:Y157	3.79	No	No	0	5	7
170	S:S:I162	S:S:V158	4.61	No	No	0	4	4
171	S:S:V160	S:S:W161	3.68	Yes	No	19	7	9
172	S:S:I162	S:S:P163	3.39	No	No	0	4	4
173	S:S:I162	S:S:L166	2.85	No	No	0	4	4
174	S:S:L167	S:S:Q202	3.99	No	Yes	1	5	3
175	S:S:I169	S:S:P170	3.39	No	No	0	3	8
176	S:S:F174	S:S:P170	2.89	Yes	No	0	4	8
177	S:S:F199	S:S:P170	8.67	Yes	No	0	5	8
178	S:S:D171	S:S:R188	13.1	Yes	No	0	4	5
179	S:S:F174	S:S:I173	12.56	Yes	No	0	4	3
180	S:S:F174	S:S:Y190	6.19	Yes	Yes	1	4	4
181	S:S:F174	S:S:W195	5.01	Yes	Yes	1	4	5
182	S:S:I185	S:S:S178	4.64	No	No	0	3	1
183	S:S:F189	S:S:S178	3.96	Yes	No	0	3	1
184	S:S:E179	S:S:Y184	10.1	No	No	0	2	5
185	S:S:A180	S:S:R183	8.3	No	No	0	1	3
186	S:S:D181	S:S:R183	11.91	No	No	0	2	3
187	S:S:D187	S:S:R188	4.76	Yes	No	0	3	5
188	S:S:D187	S:S:F189	3.58	Yes	Yes	0	3	3
189	M:M:S25	S:S:D187	5.89	No	Yes	0	9	3
190	M:M:S27	S:S:D187	8.83	No	Yes	0	6	3
191	S:S:R188	S:S:Y190	9.26	No	Yes	0	5	4
192	M:M:Y28	S:S:F189	9.28	Yes	Yes	0	8	3
193	S:S:P191	S:S:Y190	4.17	No	Yes	0	5	4
194	S:S:W195	S:S:Y190	4.82	Yes	Yes	1	5	4
195	S:S:V196	S:S:Y190	7.57	No	Yes	0	4	4
196	S:S:F199	S:S:Y190	12.38	Yes	Yes	1	5	4
197	M:M:Y28	S:S:Y190	2.98	Yes	Yes	0	8	4
198	S:S:N192	S:S:P191	3.26	No	No	0	1	5
199	S:S:L194	S:S:N192	4.12	No	No	0	2	1
200	S:S:N192	S:S:W195	7.91	No	Yes	0	1	5
201	S:S:F199	S:S:W195	4.01	Yes	Yes	1	5	5
202	S:S:L266	S:S:V197	4.47	No	No	0	3	3
203	S:S:F199	S:S:Q202	5.86	Yes	Yes	1	5	3
204	S:S:D262	S:S:Q200	5.22	No	No	0	5	5
205	S:S:Q200	S:S:S263	5.78	No	No	0	5	5
206	M:M:V24	S:S:Q200	5.73	Yes	No	0	7	5
207	S:S:F201	S:S:S263	10.57	No	No	0	4	5
208	S:S:F201	S:S:F264	5.36	No	No	0	4	4
209	S:S:Q202	S:S:V206	4.3	Yes	No	1	3	4
210	S:S:H203	S:S:Y255	6.53	Yes	Yes	1	4	7
211	S:S:H203	S:S:Y256	10.89	Yes	Yes	1	4	8
212	M:M:P23	S:S:H203	16.78	No	Yes	1	9	4
213	S:S:I204	S:S:I259	5.89	No	Yes	0	5	5
214	S:S:I209	S:S:M205	5.83	No	No	0	4	4
215	S:S:G207	S:S:Y256	2.9	No	Yes	0	5	8
216	S:S:L208	S:S:Y256	9.38	No	Yes	0	8	8
217	S:S:F249	S:S:G212	3.01	No	No	0	4	6
218	S:S:I215	S:S:I245	4.42	No	Yes	14	7	7
219	P:P:V54	S:S:L216	4.47	No	No	0	4	4
220	S:S:I222	S:S:Y219	4.84	No	Yes	0	8	8
221	S:S:V242	S:S:Y219	6.31	No	Yes	0	4	8
222	S:S:I245	S:S:Y219	3.63	Yes	Yes	14	7	8
223	S:S:I222	S:S:L238	4.28	No	No	0	8	5
224	P:P:L58	S:S:I223	9.99	No	No	0	5	4
225	P:P:L61	S:S:S224	3	No	No	0	4	4
226	S:S:L226	S:S:S229	3	No	No	0	8	5
227	P:P:Q66	S:S:S227	8.66	Yes	No	0	4	4
228	P:P:Q66	S:S:H228	7.42	Yes	No	0	4	5
229	S:S:H232	S:S:K234	10.48	No	No	0	4	7
230	S:S:K236	S:S:Q233	10.85	No	No	0	8	5
231	S:S:L238	S:S:V242	2.98	No	No	0	5	4
232	S:S:I243	S:S:K239	2.91	No	No	0	5	6
233	S:S:T240	S:S:T241	3.14	No	No	0	7	7
234	S:S:I243	S:S:L301	5.71	No	No	0	5	7
235	S:S:A247	S:S:L297	4.73	No	No	0	6	6
236	S:S:F248	S:S:F249	5.36	Yes	No	0	9	4
237	S:S:F248	S:S:W252	10.02	Yes	Yes	1	9	9
238	S:S:F248	S:S:H294	7.92	Yes	Yes	1	9	9
239	S:S:W252	S:S:Y255	5.79	Yes	Yes	1	9	7
240	S:S:A291	S:S:W252	6.48	No	Yes	0	8	9
241	S:S:H294	S:S:W252	12.7	Yes	Yes	1	9	9
242	P:P:I47	S:S:L253	2.85	No	No	0	4	5
243	S:S:P254	S:S:T287	3.5	No	No	0	9	6
244	P:P:T43	S:S:P254	3.5	No	No	0	4	9
245	S:S:Y255	S:S:Y256	4.96	Yes	Yes	1	7	8
246	S:S:I259	S:S:Y255	8.46	Yes	Yes	1	5	7
247	S:S:E288	S:S:Y255	5.61	No	Yes	0	5	7
248	M:M:V24	S:S:Y255	6.31	Yes	Yes	1	7	7
249	S:S:I259	S:S:Y256	3.63	Yes	Yes	1	5	8
250	P:P:T43	S:S:I257	4.56	No	No	0	4	6
251	P:P:S46	S:S:I257	6.19	No	No	0	5	6
252	S:S:I259	S:S:I284	5.89	Yes	No	0	5	4
253	M:M:V24	S:S:I259	6.14	Yes	Yes	1	7	5
254	P:P:I39	S:S:I261	4.42	Yes	No	6	5	5
255	P:P:P42	S:S:I261	3.39	No	No	6	5	5
256	P:P:V99	S:S:I261	10.75	No	No	6	4	5
257	S:S:D262	S:S:V280	4.38	No	Yes	0	5	5
258	S:S:D262	S:S:I284	4.2	No	No	0	5	4
259	S:S:I265	S:S:I270	2.94	Yes	No	0	3	5
260	S:S:F276	S:S:I265	5.02	Yes	Yes	6	1	3
261	S:S:E277	S:S:I265	4.1	No	Yes	0	2	3
262	S:S:I265	S:S:V280	4.61	Yes	Yes	6	3	5
263	M:M:R29	S:S:L266	3.64	Yes	No	0	9	3
264	S:S:I269	S:S:L267	2.85	No	No	0	1	1
265	S:S:E268	S:S:K271	9.45	No	No	0	2	3
266	M:M:R33	S:S:E268	10.47	No	No	0	9	2
267	S:S:I269	S:S:I270	2.94	No	No	0	1	5
268	S:S:I270	S:S:Q272	5.49	No	No	0	5	2
269	P:P:K38	S:S:Q272	4.07	No	No	0	4	2
270	S:S:C274	S:S:E275	3.04	No	No	0	5	3
271	P:P:N35	S:S:E275	3.94	Yes	No	0	3	3
272	S:S:F276	S:S:V280	5.24	Yes	Yes	6	1	5
273	P:P:N35	S:S:F276	3.62	Yes	Yes	0	3	1
274	P:P:K38	S:S:F276	3.72	No	Yes	0	4	1
275	M:M:R29	S:S:E277	8.14	Yes	No	0	9	2
276	P:P:N35	S:S:T279	4.39	Yes	No	0	3	2
277	P:P:I39	S:S:V280	3.07	Yes	Yes	6	5	5
278	M:M:L26	S:S:H281	7.71	No	No	0	9	4
279	S:S:T287	S:S:W283	10.92	No	Yes	0	6	6
280	P:P:F36	S:S:W283	3.01	No	Yes	6	4	6
281	P:P:I39	S:S:W283	10.57	Yes	Yes	6	5	6
282	P:P:T43	S:S:W283	8.49	No	Yes	0	4	6
283	S:S:E288	S:S:F292	3.5	No	Yes	0	5	7
284	M:M:K22	S:S:E288	10.8	Yes	No	0	9	5
285	S:S:C296	S:S:F293	6.98	No	Yes	0	7	5
286	S:S:C295	S:S:H294	7.37	No	Yes	0	9	9
287	S:S:N298	S:S:P299	4.89	Yes	Yes	0	9	9
288	L:L:R33	R:R:E26	8.14	No	No	21	9	2
289	L:L:F34	R:R:E26	3.5	No	No	21	6	2
290	R:R:F29	R:R:P27	8.67	No	No	0	4	5
291	R:R:C274	R:R:C28	7.28	No	No	0	5	9
292	L:L:P31	R:R:F29	4.33	No	No	0	7	4
293	R:R:H281	R:R:R30	4.51	No	No	0	4	5
294	R:R:E31	R:R:N33	5.26	No	No	0	5	6
295	R:R:A34	R:R:E32	3.02	No	No	0	1	4
296	R:R:E32	R:R:H281	3.69	No	No	0	4	4
297	R:R:N33	R:R:N35	8.17	No	No	0	6	3
298	R:R:A34	R:R:N37	4.69	No	No	0	1	3
299	R:R:A34	R:R:K282	3.21	No	No	0	1	2
300	C:C:E275	R:R:N35	3.94	No	No	0	3	3
301	C:C:T279	R:R:N35	4.39	No	No	0	2	3
302	R:R:F36	R:R:F40	9.65	No	No	0	4	5
303	C:C:W283	R:R:F36	3.01	Yes	No	0	6	4
304	R:R:I286	R:R:N37	4.25	No	No	0	6	3
305	C:C:F276	R:R:K38	3.72	Yes	No	0	1	4
306	C:C:I261	R:R:I39	5.89	No	No	0	5	5
307	C:C:V280	R:R:I39	3.07	Yes	No	0	5	5
308	C:C:W283	R:R:I39	10.57	Yes	No	0	6	5
309	R:R:F40	R:R:I44	10.05	No	No	0	5	5
310	R:R:A98	R:R:P42	3.74	No	No	0	5	5
311	R:R:P42	R:R:V99	3.53	No	No	23	5	4
312	C:C:I261	R:R:P42	3.39	No	No	23	5	5
313	C:C:P254	R:R:T43	3.5	No	No	0	9	4
314	C:C:I257	R:R:T43	4.56	No	No	0	6	4
315	C:C:W283	R:R:T43	7.28	Yes	No	0	6	4
316	R:R:I44	R:R:I48	2.94	No	Yes	0	5	7
317	R:R:A289	R:R:Y45	4	No	Yes	0	4	7
318	R:R:F292	R:R:Y45	7.22	No	Yes	0	7	7
319	C:C:I257	R:R:S46	6.19	No	No	0	6	5
320	C:C:L253	R:R:I47	2.85	No	No	0	5	4
321	R:R:I48	R:R:L91	2.85	Yes	No	0	7	8
322	R:R:F293	R:R:I48	5.02	No	Yes	0	5	7
323	R:R:C295	R:R:I48	3.27	No	Yes	0	9	7
324	R:R:F49	R:R:I53	5.02	No	No	0	6	5
325	R:R:F49	R:R:P92	13	No	No	0	6	9
326	R:R:C296	R:R:T51	5.07	No	No	0	7	5
327	R:R:I53	R:R:V88	3.07	No	No	0	5	6
328	R:R:G55	R:R:V54	3.68	No	No	0	8	4
329	C:C:L216	R:R:V54	2.98	No	No	0	4	4
330	R:R:G55	R:R:P299	4.06	No	No	0	8	9
331	R:R:N56	R:R:S81	4.47	No	No	0	9	9
332	R:R:D84	R:R:N56	12.12	No	No	0	9	9
333	C:C:I223	R:R:L58	9.99	No	No	0	4	5
334	R:R:S81	R:R:V59	8.08	No	No	0	9	8
335	R:R:I60	R:R:V82	3.07	No	No	0	7	5
336	R:R:I60	R:R:L85	2.85	No	No	0	7	7
337	C:C:S224	R:R:L61	3	No	No	0	4	4
338	R:R:M63	R:R:V62	3.04	Yes	No	0	6	7
339	R:R:D74	R:R:M63	6.93	No	Yes	11	8	6
340	R:R:M63	R:R:Y302	8.38	Yes	Yes	11	6	9
341	R:R:G64	R:R:L78	3.42	No	No	0	2	5
342	R:R:K68	R:R:Q66	4.07	No	No	24	6	4
343	C:C:S227	R:R:Q66	11.55	No	No	24	4	4
344	C:C:H228	R:R:Q66	6.18	No	No	0	5	4
345	C:C:S227	R:R:K68	3.06	No	No	24	4	6
346	R:R:K75	R:R:L69	5.64	No	No	0	6	6
347	R:R:S71	R:R:T73	3.2	No	No	0	7	7
348	R:R:D74	R:R:S71	4.42	No	No	0	8	7
349	R:R:K75	R:R:M72	4.32	No	No	0	6	6
350	R:R:A152	R:R:M72	3.22	No	No	0	3	6
351	R:R:R134	R:R:T73	3.88	No	No	0	9	7
352	R:R:D74	R:R:Y302	6.9	No	Yes	11	8	9
353	R:R:E153	R:R:K75	6.75	No	No	0	7	6
354	R:R:F129	R:R:Y76	4.13	Yes	Yes	0	5	7
355	R:R:I130	R:R:Y76	4.84	No	Yes	0	8	7
356	R:R:D133	R:R:Y76	8.05	No	Yes	0	8	7
357	R:R:A152	R:R:Y76	5.34	No	Yes	0	3	7
358	R:R:V156	R:R:Y76	3.79	No	Yes	0	5	7
359	R:R:N298	R:R:R77	12.05	Yes	No	11	9	8
360	R:R:R77	R:R:Y302	18.52	No	Yes	11	8	9
361	R:R:H79	R:R:V156	5.54	No	No	0	9	5
362	R:R:H79	R:R:Y157	6.53	No	No	12	9	7
363	R:R:H79	R:R:W161	3.17	No	Yes	12	9	9
364	R:R:I126	R:R:L80	5.71	No	No	0	7	9
365	R:R:N298	R:R:S81	5.96	Yes	No	0	9	9
366	R:R:A83	R:R:S122	3.42	No	Yes	0	8	7
367	R:R:C295	R:R:D84	7.78	No	No	0	9	9
368	R:R:F87	R:R:L91	3.65	Yes	No	0	7	8
369	R:R:F87	R:R:Y116	5.16	Yes	Yes	2	7	6
370	R:R:F87	R:R:N119	13.29	Yes	No	0	7	8
371	R:R:F292	R:R:F87	11.79	No	Yes	2	7	7
372	R:R:C295	R:R:V88	3.42	No	No	0	9	6
373	R:R:I89	R:R:T90	3.04	No	No	0	4	6
374	R:R:T90	R:R:V112	6.35	No	Yes	0	6	5
375	R:R:I115	R:R:T90	7.6	No	No	0	5	6
376	R:R:F93	R:R:W102	4.01	Yes	Yes	5	6	9
377	R:R:F104	R:R:F93	10.72	Yes	Yes	5	7	6
378	R:R:F93	R:R:L108	3.65	Yes	No	5	6	5
379	R:R:F93	R:R:V112	5.24	Yes	Yes	5	6	5
380	R:R:D97	R:R:W94	5.58	No	Yes	0	5	7
381	R:R:V112	R:R:W94	6.13	Yes	Yes	0	5	7
382	R:R:H113	R:R:W94	7.41	Yes	Yes	0	6	7
383	L:L:K22	R:R:W94	11.6	No	Yes	0	9	7
384	R:R:F104	R:R:V96	6.55	Yes	No	0	7	5
385	R:R:D97	R:R:W102	6.7	No	Yes	0	5	9
386	C:C:I261	R:R:V99	7.68	No	No	23	5	4
387	C:C:I270	R:R:V99	3.07	No	No	0	5	4
388	R:R:N101	R:R:R183	15.67	No	Yes	0	4	3
389	R:R:F104	R:R:W102	13.03	Yes	Yes	5	7	9
390	R:R:C109	R:R:W102	3.92	Yes	Yes	5	9	9
391	R:R:V112	R:R:W102	4.9	Yes	Yes	5	5	9
392	R:R:V177	R:R:W102	3.68	Yes	Yes	5	4	9
393	R:R:C186	R:R:W102	20.89	No	Yes	5	9	9
394	R:R:R183	R:R:Y103	6.17	Yes	No	0	3	3
395	R:R:F104	R:R:L108	4.87	Yes	No	5	7	5
396	R:R:K110	R:R:N106	5.6	No	No	5	7	3
397	R:R:N106	R:R:N176	9.54	No	No	5	3	4
398	R:R:N106	R:R:V177	5.91	No	Yes	5	3	4
399	R:R:C109	R:R:H113	2.95	Yes	Yes	5	9	6
400	R:R:C109	R:R:V177	3.42	Yes	Yes	5	9	4
401	R:R:C109	R:R:C186	7.28	Yes	No	5	9	9
402	R:R:A175	R:R:K110	3.21	No	No	0	4	7
403	R:R:K110	R:R:N176	6.99	No	No	5	7	4
404	R:R:A175	R:R:H113	2.93	No	Yes	0	4	6
405	R:R:C186	R:R:H113	4.42	No	Yes	5	9	6
406	R:R:H113	R:R:R188	4.51	Yes	Yes	0	6	5
407	R:R:F172	R:R:V114	10.49	No	No	0	4	5
408	R:R:L120	R:R:Y116	3.52	Yes	Yes	2	7	6
409	R:R:E288	R:R:Y116	3.37	No	Yes	2	5	6
410	R:R:F292	R:R:Y116	7.22	No	Yes	2	7	6
411	L:L:K22	R:R:Y116	4.78	No	Yes	2	9	6
412	R:R:T117	R:R:Y121	3.75	Yes	Yes	0	5	7
413	R:R:T117	R:R:T168	3.14	Yes	No	0	5	6
414	R:R:D171	R:R:T117	14.45	No	Yes	0	4	5
415	L:L:P23	R:R:T117	3.5	No	Yes	0	9	5
416	R:R:T168	R:R:V118	3.17	No	No	0	6	5
417	R:R:H294	R:R:N119	5.1	Yes	No	0	9	8
418	R:R:H203	R:R:L120	5.14	Yes	Yes	2	4	7
419	R:R:L120	R:R:W252	4.56	Yes	Yes	2	7	9
420	L:L:P23	R:R:L120	3.28	No	Yes	2	9	7
421	R:R:L167	R:R:Y121	9.38	No	Yes	0	5	7
422	R:R:Q202	R:R:Y121	6.76	No	Yes	2	3	7
423	R:R:H203	R:R:Y121	5.44	Yes	Yes	2	4	7
424	R:R:V206	R:R:Y121	3.79	No	Yes	2	4	7
425	R:R:S122	R:R:V160	3.23	Yes	Yes	12	7	7
426	R:R:S122	R:R:W161	11.12	Yes	Yes	12	7	9
427	R:R:F248	R:R:S123	6.61	Yes	No	2	9	9
428	R:R:H294	R:R:S123	5.58	Yes	No	2	9	9
429	R:R:P211	R:R:V124	3.53	No	No	0	9	7
430	R:R:L125	R:R:V160	4.47	No	Yes	0	5	7
431	R:R:L125	R:R:P163	3.28	No	No	0	5	4
432	R:R:I126	R:R:I130	2.94	No	No	0	7	8
433	R:R:I126	R:R:V160	6.14	No	Yes	0	7	7
434	R:R:I245	R:R:L127	7.14	No	No	0	7	8
435	R:R:F248	R:R:L127	6.09	Yes	No	0	9	8
436	R:R:F129	R:R:G159	3.01	Yes	No	0	5	3
437	R:R:F129	R:R:V160	5.24	Yes	Yes	0	5	7
438	R:R:I130	R:R:T241	3.04	No	Yes	0	8	7
439	R:R:I215	R:R:S131	9.29	No	No	0	7	9
440	R:R:C218	R:R:S131	3.44	No	No	0	6	9
441	R:R:S131	R:R:Y219	5.09	No	Yes	0	9	8
442	R:R:D133	R:R:R148	14.29	No	Yes	0	8	6
443	R:R:R134	R:R:T241	5.17	No	Yes	0	9	7
444	R:R:V139	R:R:Y135	6.31	No	No	0	7	8
445	R:R:C218	R:R:Y135	5.38	No	No	0	6	8
446	R:R:I221	R:R:Y135	6.04	No	No	0	4	8
447	R:R:L136	R:R:S144	4.5	No	No	25	5	5
448	R:R:L136	R:R:R148	3.64	No	Yes	25	5	6
449	R:R:A137	R:R:R148	6.91	No	Yes	0	8	6
450	R:R:I138	R:R:I222	4.42	No	No	0	8	8
451	R:R:H140	R:R:V139	4.15	No	No	0	6	7
452	R:R:K225	R:R:V139	4.55	No	No	0	4	7
453	R:R:N143	R:R:T142	5.85	No	No	0	5	5
454	R:R:R148	R:R:S144	3.95	Yes	No	25	6	5
455	R:R:E153	R:R:K149	4.05	No	No	0	7	6
456	R:R:L151	R:R:V155	2.98	No	No	0	4	2
457	R:R:W161	R:R:Y157	2.89	Yes	No	12	9	7
458	R:R:I162	R:R:V158	3.07	No	No	0	4	4
459	R:R:V160	R:R:W161	4.9	Yes	Yes	12	7	9
460	R:R:I162	R:R:P163	3.39	No	No	0	4	4
461	R:R:I169	R:R:P170	3.39	No	No	0	3	8
462	R:R:I169	R:R:I173	2.94	No	No	0	3	3
463	R:R:F174	R:R:P170	2.89	Yes	No	0	4	8
464	R:R:F199	R:R:P170	8.67	Yes	No	0	5	8
465	R:R:D171	R:R:R188	13.1	No	Yes	0	4	5
466	R:R:F174	R:R:I173	10.05	Yes	No	0	4	3
467	R:R:F174	R:R:Y190	14.44	Yes	Yes	2	4	4
468	R:R:F174	R:R:W195	5.01	Yes	Yes	2	4	5
469	R:R:V177	R:R:Y184	5.05	Yes	No	0	4	5
470	R:R:F189	R:R:S178	6.61	No	No	0	3	1
471	R:R:E179	R:R:Y184	13.47	No	No	0	2	5
472	R:R:R183	R:R:Y184	7.2	Yes	No	0	3	5
473	L:L:S27	R:R:I185	3.1	No	No	0	6	3
474	L:L:S25	R:R:D187	4.42	No	No	0	9	3
475	L:L:S27	R:R:D187	7.36	No	No	0	6	3
476	R:R:R188	R:R:Y190	9.26	Yes	Yes	0	5	4
477	L:L:S25	R:R:R188	3.95	No	Yes	0	9	5
478	L:L:Y28	R:R:F189	8.25	No	No	0	8	3
479	R:R:W195	R:R:Y190	4.82	Yes	Yes	2	5	4
480	R:R:V196	R:R:Y190	7.57	No	Yes	0	4	4
481	R:R:F199	R:R:Y190	14.44	Yes	Yes	2	5	4
482	R:R:N192	R:R:P191	4.89	No	No	0	1	5
483	R:R:L194	R:R:N192	5.49	No	No	2	2	1
484	R:R:N192	R:R:W195	4.52	No	Yes	2	1	5
485	R:R:L194	R:R:W195	3.42	No	Yes	2	2	5
486	R:R:F199	R:R:W195	3.01	Yes	Yes	2	5	5
487	R:R:L267	R:R:V197	7.45	No	No	0	1	3
488	R:R:F199	R:R:Q202	5.86	Yes	No	2	5	3
489	R:R:D262	R:R:Q200	3.92	Yes	No	0	5	5
490	R:R:Q200	R:R:S263	8.66	No	No	0	5	5
491	L:L:V24	R:R:Q200	5.73	Yes	No	0	7	5
492	R:R:F201	R:R:F264	5.36	No	No	0	4	4
493	R:R:F201	R:R:L267	3.65	No	No	0	4	1
494	R:R:Q202	R:R:V206	4.3	No	No	2	3	4
495	R:R:H203	R:R:Y255	6.53	Yes	Yes	2	4	7
496	R:R:H203	R:R:Y256	10.89	Yes	Yes	2	4	8
497	L:L:P23	R:R:H203	18.3	No	Yes	2	9	4
498	R:R:I204	R:R:I259	5.89	No	Yes	0	5	5
499	R:R:I209	R:R:M205	4.37	No	No	0	4	4
500	R:R:G207	R:R:Y256	2.9	No	Yes	0	5	8
501	R:R:I209	R:R:L208	2.85	No	No	0	4	8
502	R:R:L208	R:R:Y256	12.89	No	Yes	0	8	8
503	R:R:F249	R:R:G212	3.01	No	No	0	4	6
504	R:R:I215	R:R:I245	4.42	No	No	0	7	7
505	R:R:I222	R:R:Y219	3.63	No	Yes	0	8	8
506	R:R:T241	R:R:Y219	6.24	Yes	Yes	0	7	8
507	R:R:V242	R:R:Y219	5.05	No	Yes	0	4	8
508	R:R:I245	R:R:Y219	3.63	No	Yes	0	7	8
509	R:R:I222	R:R:L238	5.71	No	No	0	8	5
510	R:R:H232	R:R:S229	6.97	No	No	0	4	5
511	R:R:H232	R:R:R235	9.03	No	No	0	4	5
512	R:R:K236	R:R:Q233	6.78	No	No	0	8	5
513	R:R:K234	R:R:R235	7.43	No	No	0	7	5
514	R:R:L238	R:R:V242	2.98	No	No	0	5	4
515	R:R:I243	R:R:K239	4.36	No	No	0	5	6
516	R:R:T240	R:R:T241	3.14	No	Yes	0	7	7
517	R:R:I243	R:R:L301	4.28	No	No	0	5	7
518	R:R:A247	R:R:L297	4.73	No	No	0	6	6
519	R:R:F248	R:R:F249	4.29	Yes	No	0	9	4
520	R:R:F248	R:R:W252	11.02	Yes	Yes	2	9	9
521	R:R:F248	R:R:H294	9.05	Yes	Yes	2	9	9
522	R:R:W252	R:R:Y255	5.79	Yes	Yes	2	9	7
523	R:R:A291	R:R:W252	6.48	No	Yes	0	8	9
524	R:R:H294	R:R:W252	11.64	Yes	Yes	2	9	9
525	R:R:P254	R:R:T287	3.5	No	No	0	9	6
526	R:R:Y255	R:R:Y256	3.97	Yes	Yes	2	7	8
527	R:R:I259	R:R:Y255	8.46	Yes	Yes	2	5	7
528	R:R:E288	R:R:Y255	6.73	No	Yes	2	5	7
529	L:L:V24	R:R:Y255	5.05	Yes	Yes	2	7	7
530	R:R:I259	R:R:Y256	3.63	Yes	Yes	2	5	8
531	R:R:G258	R:R:I284	3.53	No	No	0	4	4
532	R:R:I259	R:R:I284	5.89	Yes	No	0	5	4
533	L:L:V24	R:R:I259	4.61	Yes	Yes	2	7	5
534	R:R:D262	R:R:V280	4.38	Yes	No	0	5	5
535	L:L:L26	R:R:D262	13.57	No	Yes	0	9	5
536	L:L:R29	R:R:D262	4.76	No	Yes	0	9	5
537	R:R:I265	R:R:I270	4.42	No	No	0	3	5
538	R:R:F276	R:R:I265	3.77	No	No	0	1	3
539	L:L:R29	R:R:L266	9.72	No	No	0	9	3
540	R:R:I269	R:R:I270	2.94	No	No	0	1	5
541	R:R:E275	R:R:G273	4.91	No	No	0	3	5
542	R:R:F276	R:R:V280	5.24	No	No	0	1	5
543	L:L:R29	R:R:E277	12.79	No	No	0	9	2
544	R:R:T287	R:R:W283	12.13	No	Yes	0	6	6
545	L:L:L26	R:R:I284	2.85	No	No	0	9	4
546	L:L:K22	R:R:E288	10.8	No	No	2	9	5
547	R:R:C296	R:R:F293	4.19	No	No	0	7	5
548	R:R:N298	R:R:P299	3.26	Yes	No	0	9	9
549	R:R:N298	R:R:Y302	4.65	Yes	Yes	11	9	9
550	M:M:S25	M:M:Y28	5.09	No	Yes	0	9	8
551	M:M:R29	M:M:R33	3.2	Yes	No	0	9	9
552	M:M:C30	M:M:C32	7.28	No	No	26	9	9
553	M:M:C30	M:M:C55	7.28	No	No	26	9	9
554	M:M:C32	M:M:C55	5.46	No	No	26	9	9
555	q:q:K22	q:q:V24	6.07	No	No	0	9	7
556	q:q:L26	q:q:V24	2.98	No	No	0	9	7
557	q:q:C55	q:q:Y28	6.72	No	No	0	9	8
558	q:q:C30	q:q:C32	7.28	No	No	0	9	9
559	q:q:P31	q:q:Q58	3.16	No	No	0	7	9
560	q:q:C55	q:q:T52	3.38	No	No	0	9	8
561	C:C:K25	C:C:K271	2.87	No	Yes	13	4	3
562	C:C:E26	C:C:P27	7.86	No	Yes	0	2	5
563	C:C:E26	C:C:F29	3.5	No	No	0	2	4
564	C:C:P27	Q:Q:C71	3.77	Yes	No	0	5	9
565	C:C:C28	Q:Q:P31	7.53	No	Yes	0	9	7
566	C:C:R30	Q:Q:R29	19.19	No	No	0	5	9
567	C:C:E31	C:C:N33	15.77	No	No	0	5	6
568	C:C:E31	C:C:N278	9.2	No	No	0	5	3
569	C:C:E31	C:C:K282	8.1	No	No	0	5	2
570	C:C:A34	C:C:N37	3.13	No	Yes	0	1	3
571	C:C:N35	P:P:E275	5.26	No	No	0	3	3
572	C:C:N35	P:P:T279	7.31	No	No	0	3	2
573	C:C:F36	C:C:I39	3.77	No	Yes	7	4	5
574	C:C:F36	C:C:F40	8.57	No	No	0	4	5
575	C:C:F36	P:P:W283	3.01	No	Yes	7	4	6
576	C:C:N37	C:C:S285	2.98	Yes	No	0	3	5
577	C:C:I286	C:C:N37	4.25	No	Yes	0	6	3
578	C:C:K38	P:P:Q272	4.07	No	No	0	4	2
579	C:C:K38	P:P:F276	3.72	No	No	0	4	1
580	C:C:I39	P:P:I261	4.42	Yes	No	0	5	5
581	C:C:I39	P:P:V280	3.07	Yes	Yes	7	5	5
582	C:C:I39	P:P:W283	10.57	Yes	Yes	7	5	6
583	C:C:F40	C:C:I44	11.3	No	No	0	5	5
584	C:C:L41	C:C:Y45	4.69	No	Yes	0	6	7
585	C:C:A289	C:C:L41	3.15	No	No	0	4	6
586	C:C:A98	C:C:P42	3.74	No	No	0	5	5
587	C:C:P42	P:P:I261	3.39	No	No	0	5	5
588	C:C:T43	P:P:P254	3.5	No	No	0	4	9
589	C:C:T43	P:P:I257	4.56	No	No	0	4	6
590	C:C:T43	P:P:W283	7.28	No	Yes	0	4	6
591	C:C:I44	C:C:I48	2.94	No	No	0	5	7
592	C:C:W94	C:C:Y45	2.89	Yes	Yes	0	7	7
593	C:C:F292	C:C:Y45	8.25	Yes	Yes	0	7	7
594	C:C:S46	P:P:I257	6.19	No	No	0	5	6
595	C:C:I47	P:P:L253	2.85	No	No	0	4	5
596	C:C:I48	C:C:L91	2.85	No	No	0	7	8
597	C:C:F293	C:C:I48	15.07	No	No	0	5	7
598	C:C:F49	C:C:L50	3.65	Yes	No	0	6	5
599	C:C:F49	C:C:L91	3.65	Yes	No	0	6	8
600	C:C:F49	C:C:P92	7.22	Yes	No	0	6	9
601	C:C:C296	C:C:T51	5.07	No	No	0	7	5
602	C:C:G55	C:C:V54	3.68	No	No	0	8	4
603	C:C:V54	P:P:L216	4.47	No	No	0	4	4
604	C:C:G55	C:C:P299	4.06	No	Yes	0	8	9
605	C:C:N56	C:C:S81	4.47	Yes	Yes	0	9	9
606	C:C:D84	C:C:N56	8.08	Yes	Yes	0	9	9
607	C:C:N56	C:C:P299	4.89	Yes	Yes	0	9	9
608	C:C:L58	P:P:I223	9.99	No	No	0	5	4
609	C:C:S81	C:C:V59	6.46	Yes	No	0	9	8
610	C:C:P299	C:C:V59	3.53	Yes	No	0	9	8
611	C:C:I60	C:C:V82	3.07	Yes	No	0	7	5
612	C:C:I60	C:C:L85	4.28	Yes	No	0	7	7
613	C:C:L61	P:P:S224	3	No	No	0	4	4
614	C:C:M63	C:C:V62	4.56	No	No	0	6	7
615	C:C:K68	C:C:V62	4.55	No	No	0	6	7
616	C:C:M63	C:C:Y302	9.58	No	No	0	6	9
617	C:C:G64	C:C:L78	3.42	No	No	0	2	5
618	C:C:Q66	P:P:S227	8.66	No	No	0	4	4
619	C:C:Q66	P:P:H228	6.18	No	No	0	4	5
620	C:C:K67	C:C:L69	7.05	No	No	0	6	6
621	C:C:K68	C:C:R70	3.71	No	No	0	6	6
622	C:C:K75	C:C:L69	7.05	No	No	0	6	6
623	C:C:S71	C:C:T73	3.2	No	No	0	7	7
624	C:C:D74	C:C:S71	8.83	No	No	0	8	7
625	C:C:K75	C:C:M72	4.32	No	No	0	6	6
626	C:C:M72	C:C:R148	6.2	No	Yes	0	6	6
627	C:C:A152	C:C:M72	3.22	No	No	0	3	6
628	C:C:R134	C:C:T73	3.88	Yes	No	0	9	7
629	C:C:D74	C:C:Y302	5.75	No	No	0	8	9
630	C:C:E153	C:C:K75	5.4	No	No	0	7	6
631	C:C:F129	C:C:Y76	3.09	No	Yes	29	5	7
632	C:C:I130	C:C:Y76	4.84	No	Yes	0	8	7
633	C:C:D133	C:C:Y76	11.49	No	Yes	0	8	7
634	C:C:L151	C:C:Y76	3.52	No	Yes	29	4	7
635	C:C:A152	C:C:Y76	5.34	No	Yes	0	3	7
636	C:C:N298	C:C:R77	6.03	Yes	No	0	9	8
637	C:C:R77	C:C:Y302	23.66	No	No	0	8	9
638	C:C:H79	C:C:V156	4.15	No	No	9	9	5
639	C:C:H79	C:C:Y157	4.36	No	No	9	9	7
640	C:C:H79	C:C:W161	3.17	No	Yes	9	9	9
641	C:C:D84	C:C:L80	4.07	Yes	No	27	9	9
642	C:C:I126	C:C:L80	4.28	No	No	0	7	9
643	C:C:L80	C:C:N298	8.24	No	Yes	27	9	9
644	C:C:N298	C:C:S81	4.47	Yes	Yes	0	9	9
645	C:C:A83	C:C:S122	3.42	No	Yes	9	8	7
646	C:C:A83	C:C:W161	3.89	No	Yes	9	8	9
647	C:C:C295	C:C:D84	9.34	No	Yes	0	9	9
648	C:C:D84	C:C:N298	4.04	Yes	Yes	27	9	9
649	C:C:F87	C:C:L91	3.65	Yes	No	0	7	8
650	C:C:F87	C:C:Y116	8.25	Yes	Yes	4	7	6
651	C:C:F87	C:C:N119	9.67	Yes	No	0	7	8
652	C:C:F292	C:C:F87	13.93	Yes	Yes	4	7	7
653	C:C:C295	C:C:F87	4.19	No	Yes	0	9	7
654	C:C:I89	C:C:T90	3.04	No	No	0	4	6
655	C:C:T90	C:C:V112	7.93	No	Yes	0	6	5
656	C:C:I115	C:C:T90	7.6	No	No	0	5	6
657	C:C:F104	C:C:F93	11.79	No	No	0	7	6
658	C:C:F93	C:C:L108	3.65	No	No	0	6	5
659	C:C:F93	C:C:V112	3.93	No	Yes	0	6	5
660	C:C:D97	C:C:W94	4.47	No	Yes	0	5	7
661	C:C:V112	C:C:W94	7.36	Yes	Yes	0	5	7
662	C:C:H113	C:C:W94	6.35	Yes	Yes	0	6	7
663	C:C:W94	Q:Q:K22	12.76	Yes	No	0	7	9
664	C:C:F104	C:C:V96	6.55	No	No	0	7	5
665	C:C:D97	C:C:W102	7.82	No	Yes	0	5	9
666	C:C:V99	P:P:I261	9.22	No	No	0	4	5
667	C:C:N101	C:C:R183	21.69	No	No	0	4	3
668	C:C:F104	C:C:W102	17.04	No	Yes	0	7	9
669	C:C:C109	C:C:W102	3.92	Yes	Yes	15	9	9
670	C:C:V112	C:C:W102	4.9	Yes	Yes	0	5	9
671	C:C:C186	C:C:W102	16.98	No	Yes	15	9	9
672	C:C:C109	C:C:H113	2.95	Yes	Yes	15	9	6
673	C:C:C109	C:C:V177	3.42	Yes	No	0	9	4
674	C:C:C109	C:C:C186	7.28	Yes	No	15	9	9
675	C:C:K110	C:C:N176	6.99	No	No	0	7	4
676	C:C:D171	C:C:H113	5.04	Yes	Yes	0	4	6
677	C:C:A175	C:C:H113	4.39	No	Yes	0	4	6
678	C:C:C186	C:C:H113	2.95	No	Yes	15	9	6
679	C:C:T168	C:C:V114	4.76	No	No	0	6	5
680	C:C:D171	C:C:V114	2.92	Yes	No	0	4	5
681	C:C:F172	C:C:V114	3.93	No	No	0	4	5
682	C:C:L120	C:C:Y116	3.52	Yes	Yes	4	7	6
683	C:C:F292	C:C:Y116	8.25	Yes	Yes	4	7	6
684	C:C:Y116	Q:Q:K22	4.78	Yes	No	0	6	9
685	C:C:T117	C:C:T168	3.14	No	No	0	5	6
686	C:C:D171	C:C:T117	7.23	Yes	No	0	4	5
687	C:C:T117	Q:Q:P23	3.5	No	No	0	5	9
688	C:C:H294	C:C:N119	5.1	Yes	No	0	9	8
689	C:C:H203	C:C:L120	6.43	Yes	Yes	4	4	7
690	C:C:L120	C:C:W252	4.56	Yes	Yes	4	7	9
691	C:C:L120	Q:Q:P23	3.28	Yes	No	4	7	9
692	C:C:L167	C:C:Y121	12.89	No	Yes	0	5	7
693	C:C:Q202	C:C:Y121	6.76	No	Yes	4	3	7
694	C:C:H203	C:C:Y121	5.44	Yes	Yes	4	4	7
695	C:C:V206	C:C:Y121	3.79	No	Yes	4	4	7
696	C:C:S122	C:C:V160	3.23	Yes	Yes	9	7	7
697	C:C:S122	C:C:W161	11.12	Yes	Yes	9	7	9
698	C:C:F248	C:C:S123	6.61	Yes	No	4	9	9
699	C:C:H294	C:C:S123	5.58	Yes	No	4	9	9
700	C:C:P211	C:C:V124	3.53	No	No	0	9	7
701	C:C:F248	C:C:V124	3.93	Yes	No	0	9	7
702	C:C:L125	C:C:V160	2.98	No	Yes	0	5	7
703	C:C:I126	C:C:I130	2.94	No	No	0	7	8
704	C:C:I126	C:C:V160	9.22	No	Yes	0	7	7
705	C:C:I245	C:C:L127	2.85	No	No	0	7	8
706	C:C:F248	C:C:L127	7.31	Yes	No	0	9	8
707	C:C:F129	C:C:L151	4.87	No	No	29	5	4
708	C:C:F129	C:C:G159	3.01	No	No	0	5	3
709	C:C:I215	C:C:S131	9.29	No	No	0	7	9
710	C:C:C218	C:C:S131	3.44	Yes	No	0	6	9
711	C:C:D133	C:C:R148	10.72	No	Yes	0	8	6
712	C:C:A137	C:C:R134	5.53	No	Yes	28	8	9
713	C:C:R134	C:C:R148	3.2	Yes	Yes	28	9	6
714	C:C:V139	C:C:Y135	6.31	No	Yes	30	7	8
715	C:C:H140	C:C:Y135	4.36	Yes	Yes	30	6	8
716	C:C:C218	C:C:Y135	5.38	Yes	Yes	0	6	8
717	C:C:I221	C:C:Y135	6.04	No	Yes	0	4	8
718	C:C:L136	C:C:S144	4.5	No	No	0	5	5
719	C:C:A137	C:C:R148	6.91	No	Yes	28	8	6
720	C:C:I138	C:C:I222	5.89	No	No	0	8	8
721	C:C:I138	C:C:K234	2.91	No	No	0	8	7
722	C:C:H140	C:C:V139	9.69	Yes	No	30	6	7
723	C:C:K225	C:C:V139	4.55	No	No	0	4	7
724	C:C:N143	C:C:T142	5.85	No	No	0	5	5
725	C:C:Q145	C:C:R146	8.18	No	No	0	5	5
726	C:C:P147	C:C:R146	2.88	No	No	0	4	5
727	C:C:E153	C:C:K149	4.05	No	No	0	7	6
728	C:C:V156	C:C:Y157	3.79	No	No	9	5	7
729	C:C:I162	C:C:V158	3.07	No	No	0	4	4
730	C:C:V160	C:C:W161	3.68	Yes	Yes	9	7	9
731	C:C:I162	C:C:P163	3.39	No	No	0	4	4
732	C:C:I162	C:C:L166	2.85	No	No	0	4	4
733	C:C:I169	C:C:P170	3.39	No	Yes	0	3	8
734	C:C:F174	C:C:P170	2.89	Yes	Yes	0	4	8
735	C:C:P170	C:C:R188	2.88	Yes	Yes	0	8	5
736	C:C:F199	C:C:P170	8.67	Yes	Yes	0	5	8
737	C:C:D171	C:C:R188	11.91	Yes	Yes	0	4	5
738	C:C:F174	C:C:I173	16.33	Yes	No	0	4	3
739	C:C:F174	C:C:Y190	6.19	Yes	Yes	4	4	4
740	C:C:F174	C:C:W195	5.01	Yes	Yes	4	4	5
741	C:C:F189	C:C:S178	5.28	Yes	No	0	3	1
742	C:C:E179	C:C:Y184	10.1	No	No	0	2	5
743	C:C:D181	C:C:R183	7.15	No	No	0	2	3
744	C:C:I185	Q:Q:S27	3.1	No	No	0	3	6
745	C:C:D187	C:C:R188	3.57	Yes	Yes	0	3	5
746	C:C:D187	C:C:F189	3.58	Yes	Yes	0	3	3
747	C:C:D187	Q:Q:S25	5.89	Yes	No	0	3	9
748	C:C:D187	Q:Q:S27	7.36	Yes	No	0	3	6
749	C:C:R188	C:C:Y190	15.43	Yes	Yes	0	5	4
750	C:C:F189	Q:Q:Y28	10.32	Yes	No	0	3	8
751	C:C:P191	C:C:Y190	4.17	No	Yes	0	5	4
752	C:C:W195	C:C:Y190	3.86	Yes	Yes	4	5	4
753	C:C:V196	C:C:Y190	6.31	No	Yes	0	4	4
754	C:C:F199	C:C:Y190	11.35	Yes	Yes	4	5	4
755	C:C:Y190	Q:Q:Y28	2.98	Yes	No	0	4	8
756	C:C:N192	C:C:P191	3.26	No	No	0	1	5
757	C:C:L194	C:C:N192	5.49	No	No	0	2	1
758	C:C:N192	C:C:W195	7.91	No	Yes	0	1	5
759	C:C:D193	C:C:V196	4.38	No	No	0	1	4
760	C:C:F199	C:C:W195	5.01	Yes	Yes	4	5	5
761	C:C:Q200	C:C:V196	2.87	Yes	No	0	5	4
762	C:C:L266	C:C:V197	2.98	No	No	0	3	3
763	C:C:L267	C:C:V197	4.47	No	No	0	1	3
764	C:C:F199	C:C:Q202	5.86	Yes	No	4	5	3
765	C:C:D262	C:C:Q200	3.92	No	Yes	0	5	5
766	C:C:Q200	C:C:S263	4.33	Yes	No	0	5	5
767	C:C:Q200	Q:Q:V24	8.6	Yes	No	0	5	7
768	C:C:F201	C:C:S263	6.61	No	No	0	4	5
769	C:C:F201	C:C:F264	3.22	No	No	0	4	4
770	C:C:Q202	C:C:V206	4.3	No	No	4	3	4
771	C:C:H203	C:C:Y255	5.44	Yes	Yes	4	4	7
772	C:C:H203	C:C:Y256	9.8	Yes	Yes	4	4	8
773	C:C:H203	Q:Q:P23	16.78	Yes	No	4	4	9
774	C:C:I204	C:C:I259	5.89	No	Yes	0	5	5
775	C:C:I209	C:C:M205	5.83	No	No	0	4	4
776	C:C:G207	C:C:Y256	2.9	No	Yes	0	5	8
777	C:C:L208	C:C:Y256	11.72	No	Yes	0	8	8
778	C:C:F249	C:C:G212	3.01	No	No	0	4	6
779	C:C:I215	C:C:I245	4.42	No	No	0	7	7
780	C:C:I222	C:C:Y219	3.63	No	Yes	0	8	8
781	C:C:V242	C:C:Y219	6.31	No	Yes	0	4	8
782	C:C:I245	C:C:Y219	4.84	No	Yes	0	7	8
783	C:C:I222	C:C:L238	4.28	No	No	0	8	5
784	C:C:L226	C:C:S229	3	No	No	0	8	5
785	C:C:H232	C:C:K234	9.17	No	No	0	4	7
786	C:C:K236	C:C:Q233	10.85	No	No	0	8	5
787	C:C:I243	C:C:K239	2.91	No	No	0	5	6
788	C:C:T240	C:C:T241	3.14	No	No	0	7	7
789	C:C:I243	C:C:L301	5.71	No	No	0	5	7
790	C:C:A247	C:C:L297	4.73	No	No	0	6	6
791	C:C:F248	C:C:F249	5.36	Yes	No	0	9	4
792	C:C:F248	C:C:W252	13.03	Yes	Yes	4	9	9
793	C:C:F248	C:C:H294	7.92	Yes	Yes	4	9	9
794	C:C:W252	C:C:Y255	6.75	Yes	Yes	4	9	7
795	C:C:W252	C:C:Y256	2.89	Yes	Yes	4	9	8
796	C:C:A291	C:C:W252	6.48	No	Yes	0	8	9
797	C:C:H294	C:C:W252	11.64	Yes	Yes	4	9	9
798	C:C:P254	C:C:T287	3.5	No	No	0	9	6
799	C:C:Y255	C:C:Y256	3.97	Yes	Yes	4	7	8
800	C:C:I259	C:C:Y255	9.67	Yes	Yes	4	5	7
801	C:C:E288	C:C:Y255	6.73	No	Yes	0	5	7
802	C:C:Y255	Q:Q:V24	7.57	Yes	No	4	7	7
803	C:C:I259	C:C:Y256	3.63	Yes	Yes	4	5	8
804	C:C:I259	C:C:I284	2.94	Yes	No	0	5	4
805	C:C:I259	Q:Q:V24	4.61	Yes	No	4	5	7
806	C:C:D262	C:C:V280	4.38	No	Yes	0	5	5
807	C:C:D262	C:C:H281	5.04	No	Yes	0	5	4
808	C:C:I265	C:C:I270	4.42	Yes	No	0	3	5
809	C:C:F276	C:C:I265	3.77	Yes	Yes	22	1	3
810	C:C:E277	C:C:I265	4.1	No	Yes	0	2	3
811	C:C:I265	C:C:V280	4.61	Yes	Yes	22	3	5
812	C:C:E268	C:C:K271	4.05	No	Yes	13	2	3
813	C:C:E268	Q:Q:R33	12.79	No	No	13	2	9
814	C:C:K271	Q:Q:R33	3.71	Yes	No	13	3	9
815	C:C:C274	C:C:E275	3.04	No	No	0	5	3
816	C:C:F276	C:C:V280	5.24	Yes	Yes	22	1	5
817	C:C:E277	C:C:H281	16	No	Yes	0	2	4
818	C:C:N278	Q:Q:R29	3.62	No	No	0	3	9
819	C:C:H281	Q:Q:L26	9	Yes	No	0	4	9
820	C:C:H281	Q:Q:R29	5.64	Yes	No	0	4	9
821	C:C:T287	C:C:W283	12.13	No	Yes	0	6	6
822	C:C:E288	C:C:F292	3.5	No	Yes	0	5	7
823	C:C:E288	Q:Q:K22	10.8	No	No	0	5	9
824	C:C:C296	C:C:F293	5.59	No	No	0	7	5
825	C:C:C295	C:C:H294	7.37	No	Yes	0	9	9
826	C:C:N298	C:C:P299	4.89	Yes	Yes	0	9	9
827	P:P:E26	P:P:P27	7.86	No	Yes	0	2	5
828	P:P:E26	P:P:F29	4.66	No	No	0	2	4
829	P:P:C274	P:P:E26	4.56	No	No	0	5	2
830	P:P:P27	U:U:C71	5.65	Yes	No	0	5	9
831	P:P:H281	P:P:R30	5.64	Yes	No	0	4	5
832	P:P:E31	P:P:E32	5.07	Yes	No	31	5	4
833	P:P:E31	P:P:N33	10.52	Yes	No	31	5	6
834	P:P:E31	P:P:N278	3.94	Yes	No	0	5	3
835	P:P:E31	P:P:K282	6.75	Yes	No	0	5	2
836	P:P:E32	P:P:N33	5.26	No	No	31	4	6
837	P:P:N33	P:P:N35	5.45	No	Yes	0	6	3
838	P:P:F36	P:P:I39	3.77	No	Yes	6	4	5
839	P:P:F36	P:P:F40	8.57	No	No	0	4	5
840	P:P:I286	P:P:N37	8.5	No	No	0	6	3
841	P:P:F40	P:P:I44	6.28	No	No	0	5	5
842	P:P:L41	P:P:Y45	4.69	No	Yes	0	6	7
843	P:P:A289	P:P:L41	3.15	No	No	0	4	6
844	P:P:A98	P:P:P42	3.74	No	No	0	5	5
845	P:P:P42	P:P:V99	5.3	No	No	6	5	4
846	P:P:I44	P:P:I48	2.94	No	No	0	5	7
847	P:P:L91	P:P:Y45	3.52	No	Yes	0	8	7
848	P:P:W94	P:P:Y45	2.89	Yes	Yes	0	7	7
849	P:P:F292	P:P:Y45	7.22	Yes	Yes	0	7	7
850	P:P:I48	P:P:L91	2.85	No	No	0	7	8
851	P:P:F293	P:P:I48	13.82	Yes	No	0	5	7
852	P:P:F49	P:P:L50	3.65	No	No	0	6	5
853	P:P:F49	P:P:P92	7.22	No	No	0	6	9
854	P:P:C296	P:P:T51	5.07	No	No	0	7	5
855	P:P:I53	P:P:V88	3.07	No	No	0	5	6
856	P:P:G55	P:P:V54	3.68	No	No	0	8	4
857	P:P:G55	P:P:P299	4.06	No	Yes	0	8	9
858	P:P:N56	P:P:S81	4.47	No	Yes	0	9	9
859	P:P:D84	P:P:N56	9.42	No	No	0	9	9
860	P:P:N56	P:P:P299	4.89	No	Yes	0	9	9
861	P:P:S81	P:P:V59	8.08	Yes	No	0	9	8
862	P:P:P299	P:P:V59	3.53	Yes	No	0	9	8
863	P:P:I60	P:P:V82	3.07	Yes	No	0	7	5
864	P:P:I60	P:P:L85	2.85	Yes	No	0	7	7
865	P:P:M63	P:P:V62	3.04	No	No	32	6	7
866	P:P:K68	P:P:V62	6.07	No	No	32	6	7
867	P:P:K68	P:P:M63	2.88	No	No	32	6	6
868	P:P:M63	P:P:Y302	10.78	No	No	0	6	9
869	P:P:G64	P:P:L78	3.42	No	No	0	2	5
870	P:P:K67	P:P:L69	7.05	No	No	0	6	6
871	P:P:K68	P:P:R70	6.19	No	No	0	6	6
872	P:P:K75	P:P:L69	5.64	No	No	0	6	6
873	P:P:S71	P:P:T73	3.2	No	No	0	7	7
874	P:P:D74	P:P:S71	4.42	No	No	0	8	7
875	P:P:K75	P:P:M72	4.32	No	No	0	6	6
876	P:P:M72	P:P:R148	6.2	No	No	0	6	6
877	P:P:A152	P:P:M72	3.22	No	No	0	3	6
878	P:P:D74	P:P:Y302	6.9	No	No	0	8	9
879	P:P:E153	P:P:K75	5.4	No	No	0	7	6
880	P:P:F129	P:P:Y76	3.09	No	Yes	33	5	7
881	P:P:I130	P:P:Y76	4.84	No	Yes	0	8	7
882	P:P:D133	P:P:Y76	9.2	No	Yes	0	8	7
883	P:P:L151	P:P:Y76	3.52	No	Yes	33	4	7
884	P:P:A152	P:P:Y76	5.34	No	Yes	0	3	7
885	P:P:N298	P:P:R77	4.82	Yes	No	0	9	8
886	P:P:R77	P:P:Y302	25.72	No	No	0	8	9
887	P:P:H79	P:P:I126	3.98	No	Yes	0	9	7
888	P:P:H79	P:P:Y157	4.36	No	No	0	9	7
889	P:P:H79	P:P:W161	4.23	No	No	0	9	9
890	P:P:D84	P:P:L80	4.07	No	No	0	9	9
891	P:P:I126	P:P:L80	4.28	Yes	No	0	7	9
892	P:P:L80	P:P:N298	5.49	No	Yes	0	9	9
893	P:P:N298	P:P:S81	4.47	Yes	Yes	0	9	9
894	P:P:A83	P:P:S122	3.42	No	Yes	0	8	7
895	P:P:C295	P:P:D84	7.78	No	No	0	9	9
896	P:P:F87	P:P:L91	3.65	Yes	No	0	7	8
897	P:P:F87	P:P:Y116	8.25	Yes	No	8	7	6
898	P:P:F87	P:P:N119	13.29	Yes	No	0	7	8
899	P:P:F292	P:P:F87	15	Yes	Yes	8	7	7
900	P:P:C295	P:P:V88	3.42	No	No	0	9	6
901	P:P:I89	P:P:T90	3.04	No	No	0	4	6
902	P:P:T90	P:P:V112	6.35	No	Yes	0	6	5
903	P:P:I115	P:P:T90	7.6	No	No	0	5	6
904	P:P:F104	P:P:F93	11.79	No	No	0	7	6
905	P:P:F93	P:P:L108	3.65	No	No	0	6	5
906	P:P:F93	P:P:V112	3.93	No	Yes	0	6	5
907	P:P:D97	P:P:W94	3.35	No	Yes	0	5	7
908	P:P:V112	P:P:W94	7.36	Yes	Yes	0	5	7
909	P:P:H113	P:P:W94	7.41	Yes	Yes	8	6	7
910	P:P:W94	U:U:K22	12.76	Yes	Yes	8	7	9
911	P:P:F104	P:P:V96	5.24	No	No	0	7	5
912	P:P:D97	P:P:W102	8.93	No	Yes	0	5	9
913	P:P:N101	P:P:R183	18.08	No	No	0	4	3
914	P:P:F104	P:P:W102	18.04	No	Yes	0	7	9
915	P:P:C109	P:P:W102	3.92	Yes	Yes	8	9	9
916	P:P:V112	P:P:W102	4.9	Yes	Yes	0	5	9
917	P:P:C186	P:P:W102	18.28	No	Yes	8	9	9
918	P:P:C109	P:P:H113	2.95	Yes	Yes	8	9	6
919	P:P:C109	P:P:V177	3.42	Yes	No	0	9	4
920	P:P:C109	P:P:C186	7.28	Yes	No	8	9	9
921	P:P:K110	P:P:N176	6.99	No	No	0	7	4
922	P:P:D171	P:P:H113	6.3	Yes	Yes	0	4	6
923	P:P:A175	P:P:H113	4.39	No	Yes	0	4	6
924	P:P:C186	P:P:H113	4.42	No	Yes	8	9	6
925	P:P:H113	U:U:K22	5.24	Yes	Yes	8	6	9
926	P:P:T168	P:P:V114	4.76	Yes	No	35	6	5
927	P:P:D171	P:P:V114	2.92	Yes	No	0	4	5
928	P:P:F172	P:P:V114	5.24	No	No	35	4	5
929	P:P:F292	P:P:Y116	7.22	Yes	No	8	7	6
930	P:P:Y116	U:U:K22	7.17	No	Yes	8	6	9
931	P:P:T117	P:P:T168	3.14	No	Yes	0	5	6
932	P:P:D171	P:P:T117	7.23	Yes	No	0	4	5
933	P:P:T117	U:U:P23	3.5	No	Yes	0	5	9
934	P:P:H294	P:P:N119	5.1	Yes	No	0	9	8
935	P:P:H203	P:P:L120	6.43	Yes	No	3	4	7
936	P:P:L120	P:P:W252	4.56	No	Yes	3	7	9
937	P:P:L120	U:U:P23	3.28	No	Yes	3	7	9
938	P:P:L167	P:P:Y121	12.89	No	Yes	3	5	7
939	P:P:Q202	P:P:Y121	6.76	Yes	Yes	3	3	7
940	P:P:H203	P:P:Y121	5.44	Yes	Yes	3	4	7
941	P:P:V206	P:P:Y121	3.79	No	Yes	3	4	7
942	P:P:S122	P:P:V160	3.23	Yes	Yes	34	7	7
943	P:P:S122	P:P:W161	11.12	Yes	No	34	7	9
944	P:P:F248	P:P:S123	6.61	Yes	No	3	9	9
945	P:P:H294	P:P:S123	5.58	Yes	No	3	9	9
946	P:P:P211	P:P:V124	3.53	No	No	0	9	7
947	P:P:F248	P:P:V124	3.93	Yes	No	0	9	7
948	P:P:L125	P:P:V160	2.98	No	Yes	0	5	7
949	P:P:I126	P:P:I130	2.94	Yes	No	0	7	8
950	P:P:I126	P:P:V160	9.22	Yes	Yes	0	7	7
951	P:P:L127	P:P:L244	4.15	No	No	0	8	7
952	P:P:I245	P:P:L127	2.85	No	No	0	7	8
953	P:P:F248	P:P:L127	6.09	Yes	No	0	9	8
954	P:P:F129	P:P:L151	4.87	No	No	33	5	4
955	P:P:F129	P:P:G159	3.01	No	No	0	5	3
956	P:P:I215	P:P:S131	9.29	No	No	0	7	9
957	P:P:C218	P:P:S131	3.44	No	No	0	6	9
958	P:P:D133	P:P:R148	10.72	No	No	0	8	6
959	P:P:A137	P:P:R134	4.15	No	No	0	8	9
960	P:P:V139	P:P:Y135	6.31	No	Yes	36	7	8
961	P:P:H140	P:P:Y135	3.27	Yes	Yes	36	6	8
962	P:P:C218	P:P:Y135	5.38	No	Yes	0	6	8
963	P:P:I221	P:P:Y135	6.04	No	Yes	0	4	8
964	P:P:H140	P:P:L136	3.86	Yes	No	0	6	5
965	P:P:L136	P:P:S144	4.5	No	No	0	5	5
966	P:P:A137	P:P:R148	6.91	No	No	0	8	6
967	P:P:I138	P:P:I222	4.42	No	No	0	8	8
968	P:P:H140	P:P:V139	11.07	Yes	No	36	6	7
969	P:P:K225	P:P:V139	3.04	No	No	0	4	7
970	P:P:N143	P:P:T142	5.85	No	No	0	5	5
971	P:P:Q145	P:P:R146	8.18	No	No	0	5	5
972	P:P:P147	P:P:R146	2.88	No	No	0	4	5
973	P:P:E153	P:P:K149	4.05	No	No	0	7	6
974	P:P:V156	P:P:Y157	3.79	No	No	0	5	7
975	P:P:I162	P:P:V158	3.07	No	No	0	4	4
976	P:P:V160	P:P:W161	3.68	Yes	No	34	7	9
977	P:P:I162	P:P:P163	3.39	No	No	0	4	4
978	P:P:I162	P:P:L166	2.85	No	No	0	4	4
979	P:P:L167	P:P:Q202	3.99	No	Yes	3	5	3
980	P:P:F172	P:P:T168	3.89	No	Yes	35	4	6
981	P:P:I169	P:P:P170	3.39	No	No	0	3	8
982	P:P:P170	P:P:R188	2.88	No	Yes	0	8	5
983	P:P:F199	P:P:P170	8.67	Yes	No	0	5	8
984	P:P:D171	P:P:R188	13.1	Yes	Yes	0	4	5
985	P:P:F174	P:P:I173	3.77	Yes	No	0	4	3
986	P:P:F174	P:P:Y190	6.19	Yes	Yes	3	4	4
987	P:P:F174	P:P:P191	2.89	Yes	No	3	4	5
988	P:P:F174	P:P:W195	6.01	Yes	Yes	3	4	5
989	P:P:I185	P:P:S178	3.1	No	No	0	3	1
990	P:P:F189	P:P:S178	5.28	Yes	No	0	3	1
991	P:P:E179	P:P:Y184	11.22	No	No	0	2	5
992	P:P:D181	P:P:R183	3.57	No	No	0	2	3
993	P:P:I185	U:U:S27	3.1	No	No	0	3	6
994	P:P:D187	P:P:F189	3.58	Yes	Yes	3	3	3
995	P:P:D187	U:U:S25	5.89	Yes	No	3	3	9
996	P:P:D187	U:U:S27	7.36	Yes	No	0	3	6
997	P:P:D187	U:U:Y28	3.45	Yes	Yes	3	3	8
998	P:P:R188	P:P:Y190	9.26	Yes	Yes	0	5	4
999	P:P:R188	U:U:P23	4.32	Yes	Yes	0	5	9
1000	P:P:F189	U:U:Y28	7.22	Yes	Yes	3	3	8
1001	P:P:P191	P:P:Y190	4.17	No	Yes	3	5	4
1002	P:P:W195	P:P:Y190	4.82	Yes	Yes	3	5	4
1003	P:P:V196	P:P:Y190	6.31	No	Yes	0	4	4
1004	P:P:F199	P:P:Y190	13.41	Yes	Yes	3	5	4
1005	P:P:N192	P:P:P191	3.26	No	No	0	1	5
1006	P:P:L194	P:P:N192	4.12	No	No	0	2	1
1007	P:P:N192	P:P:W195	7.91	No	Yes	0	1	5
1008	P:P:D193	P:P:V196	4.38	No	No	0	1	4
1009	P:P:D193	U:U:C30	3.11	No	No	0	1	9
1010	P:P:F199	P:P:W195	4.01	Yes	Yes	3	5	5
1011	P:P:L266	P:P:V197	4.47	No	No	0	3	3
1012	P:P:L267	P:P:V197	7.45	No	No	0	1	3
1013	P:P:F199	P:P:Q202	5.86	Yes	Yes	3	5	3
1014	P:P:D262	P:P:Q200	5.22	No	No	0	5	5
1015	P:P:Q200	P:P:S263	2.89	No	No	0	5	5
1016	P:P:Q200	U:U:V24	4.3	No	No	0	5	7
1017	P:P:F201	P:P:S263	10.57	No	No	0	4	5
1018	P:P:F201	P:P:F264	5.36	No	No	0	4	4
1019	P:P:Q202	P:P:V206	4.3	Yes	No	3	3	4
1020	P:P:H203	P:P:Y255	5.44	Yes	Yes	3	4	7
1021	P:P:H203	P:P:Y256	10.89	Yes	Yes	3	4	8
1022	P:P:H203	U:U:P23	15.25	Yes	Yes	3	4	9
1023	P:P:I204	P:P:I259	5.89	No	Yes	0	5	5
1024	P:P:I209	P:P:M205	5.83	No	No	0	4	4
1025	P:P:G207	P:P:Y256	2.9	No	Yes	0	5	8
1026	P:P:L208	P:P:Y256	10.55	No	Yes	0	8	8
1027	P:P:F249	P:P:G212	3.01	No	No	0	4	6
1028	P:P:I215	P:P:I245	4.42	No	No	0	7	7
1029	P:P:I222	P:P:Y219	3.63	No	Yes	0	8	8
1030	P:P:V242	P:P:Y219	6.31	No	Yes	0	4	8
1031	P:P:I245	P:P:Y219	4.84	No	Yes	0	7	8
1032	P:P:I222	P:P:L238	4.28	No	No	0	8	5
1033	P:P:L226	P:P:S229	3	No	No	0	8	5
1034	P:P:K234	P:P:S229	6.12	No	No	0	7	5
1035	P:P:H232	P:P:K234	14.41	No	No	0	4	7
1036	P:P:K236	P:P:Q233	10.85	No	No	0	8	5
1037	P:P:I243	P:P:K239	2.91	No	No	0	5	6
1038	P:P:T240	P:P:T241	3.14	No	No	0	7	7
1039	P:P:I243	P:P:L301	5.71	No	No	0	5	7
1040	P:P:A247	P:P:L297	4.73	No	No	0	6	6
1041	P:P:F248	P:P:F249	5.36	Yes	No	0	9	4
1042	P:P:F248	P:P:W252	10.02	Yes	Yes	3	9	9
1043	P:P:F248	P:P:H294	7.92	Yes	Yes	3	9	9
1044	P:P:W252	P:P:Y255	6.75	Yes	Yes	3	9	7
1045	P:P:A291	P:P:W252	6.48	No	Yes	0	8	9
1046	P:P:H294	P:P:W252	11.64	Yes	Yes	3	9	9
1047	P:P:P254	P:P:T287	3.5	No	No	0	9	6
1048	P:P:Y255	P:P:Y256	3.97	Yes	Yes	3	7	8
1049	P:P:I259	P:P:Y255	10.88	Yes	Yes	3	5	7
1050	P:P:T287	P:P:Y255	3.75	No	Yes	0	6	7
1051	P:P:E288	P:P:Y255	5.61	No	Yes	0	5	7
1052	P:P:Y255	U:U:V24	5.05	Yes	No	3	7	7
1053	P:P:I259	P:P:Y256	3.63	Yes	Yes	3	5	8
1054	P:P:I259	P:P:I284	5.89	Yes	No	0	5	4
1055	P:P:I259	U:U:V24	3.07	Yes	No	3	5	7
1056	P:P:D262	P:P:E277	3.9	No	Yes	0	5	2
1057	P:P:D262	P:P:V280	4.38	No	Yes	0	5	5
1058	P:P:I265	P:P:I270	2.94	Yes	No	0	3	5
1059	P:P:F276	P:P:I265	6.28	No	Yes	7	1	3
1060	P:P:E277	P:P:I265	4.1	Yes	Yes	7	2	3
1061	P:P:I265	P:P:V280	4.61	Yes	Yes	7	3	5
1062	P:P:L266	U:U:R29	4.86	No	Yes	0	3	9
1063	P:P:E268	U:U:R33	8.14	No	No	0	2	9
1064	P:P:I269	P:P:I270	2.94	No	No	0	1	5
1065	P:P:I270	P:P:Q272	5.49	No	No	0	5	2
1066	P:P:G273	P:P:Q272	4.93	No	No	0	5	2
1067	P:P:F276	P:P:V280	6.55	No	Yes	7	1	5
1068	P:P:E277	P:P:H281	18.46	Yes	Yes	7	2	4
1069	P:P:E277	U:U:R29	4.65	Yes	Yes	7	2	9
1070	P:P:H281	U:U:L26	6.43	Yes	No	0	4	9
1071	P:P:H281	U:U:R29	3.39	Yes	Yes	7	4	9
1072	P:P:T287	P:P:W283	12.13	No	Yes	0	6	6
1073	P:P:S285	U:U:L26	4.5	No	No	0	5	9
1074	P:P:E288	P:P:F292	3.5	No	Yes	0	5	7
1075	P:P:E288	U:U:K22	9.45	No	Yes	0	5	9
1076	P:P:C296	P:P:F293	5.59	No	Yes	0	7	5
1077	P:P:C295	P:P:H294	7.37	No	Yes	0	9	9
1078	P:P:N298	P:P:P299	4.89	Yes	Yes	0	9	9
1079	Y:Y:K22	Y:Y:V24	7.59	No	No	0	9	7
1080	Y:Y:L26	Y:Y:V24	4.47	No	No	0	9	7
1081	Y:Y:C55	Y:Y:Y28	5.38	No	No	0	9	8
1082	Y:Y:C30	Y:Y:C32	7.28	No	No	37	9	9
1083	Y:Y:C55	Y:Y:T52	3.38	No	No	0	9	8
1084	J:J:K22	J:J:V24	6.07	No	No	0	9	7
1085	J:J:L26	J:J:V24	4.47	No	No	0	9	7
1086	J:J:C55	J:J:Y28	5.38	No	No	0	9	8
1087	J:J:C30	J:J:C32	7.28	No	No	0	9	9
1088	J:J:C55	J:J:T52	3.38	No	No	0	9	8
1089	N:N:K22	N:N:V24	3.04	No	No	0	9	7
1090	N:N:L26	N:N:V24	5.96	No	No	0	9	7
1091	N:N:C55	N:N:Y28	6.72	No	No	0	9	8
1092	N:N:R29	N:N:R33	3.2	No	No	0	9	9
1093	N:N:C30	N:N:C32	7.28	No	No	0	9	9
1094	N:N:C55	N:N:T52	3.38	No	No	0	9	8
1095	Q:Q:S25	Q:Q:Y28	5.09	No	No	0	9	8
1096	Q:Q:C30	Q:Q:C32	7.28	No	No	0	9	9
1097	Q:Q:C30	Q:Q:C55	3.64	No	No	0	9	9
1098	Q:Q:P31	Q:Q:Q58	3.16	Yes	No	0	7	9
1099	Q:Q:C55	Q:Q:T52	3.38	No	No	0	9	8
1100	U:U:S25	U:U:Y28	5.09	No	Yes	3	9	8
1101	U:U:R29	U:U:R33	7.46	Yes	No	0	9	9
1102	U:U:C30	U:U:C32	7.28	No	No	0	9	9
1103	U:U:C55	U:U:T52	3.38	No	No	0	9	8
1104	L:L:L26	L:L:V24	4.47	No	Yes	0	9	7
1105	L:L:S25	L:L:Y28	5.09	No	No	0	9	8
1106	L:L:C30	L:L:C32	7.28	No	No	0	9	9
1107	L:L:C30	L:L:C55	7.28	No	No	0	9	9
1108	L:L:F34	L:L:R33	3.21	No	No	21	6	9
1109	L:L:C55	L:L:T52	3.38	No	No	0	9	8
1110	S:S:L210	S:S:M205	2.83	No	No	0	6	4
1111	C:C:L210	C:C:M205	2.83	No	No	0	6	4
1112	P:P:L210	P:P:M205	2.83	No	No	0	6	4
1113	S:S:K234	S:S:L226	2.82	No	No	0	7	8
1114	C:C:K154	C:C:L150	2.82	No	No	0	3	4
1115	C:C:K234	C:C:L226	2.82	No	No	0	7	8
1116	S:S:G258	S:S:W283	2.81	No	Yes	0	4	6
1117	C:C:G258	C:C:W283	2.81	No	Yes	0	4	6
1118	P:P:G258	P:P:W283	2.81	No	Yes	0	4	6
1119	S:S:K38	S:S:N35	2.8	No	Yes	0	4	3
1120	S:S:K282	S:S:N37	2.8	No	No	0	2	3
1121	S:S:H281	S:S:S285	2.79	No	No	0	4	5
1122	R:R:H281	R:R:S285	2.79	No	No	0	4	5
1123	C:C:C28	C:C:R30	2.79	No	No	0	9	5
1124	C:C:H140	C:C:S144	2.79	Yes	No	0	6	5
1125	R:R:L253	S:S:L50	2.77	No	No	0	5	5
1126	S:S:L127	S:S:L244	2.77	No	No	0	8	7
1127	S:S:L208	S:S:L253	2.77	No	No	0	8	5
1128	P:P:L50	S:S:L253	2.77	No	No	0	5	5
1129	R:R:L127	R:R:L244	2.77	No	No	0	8	7
1130	R:R:L132	R:R:L136	2.77	No	No	0	6	5
1131	R:R:L208	R:R:L253	2.77	No	No	0	8	5
1132	R:R:L244	R:R:L297	2.77	No	No	0	7	6
1133	C:C:L50	P:P:L253	2.77	No	No	0	5	5
1134	C:C:A180	C:C:R183	2.77	No	No	0	1	3
1135	C:C:L208	C:C:L253	2.77	No	No	0	8	5
1136	P:P:L132	P:P:L151	2.77	No	No	0	6	4
1137	P:P:A180	P:P:R183	2.77	No	No	0	1	3
1138	P:P:L208	P:P:L253	2.77	No	No	0	8	5
1139	S:S:L85	S:S:N56	2.75	No	Yes	0	7	9
1140	R:R:L85	R:R:N56	2.75	No	No	0	7	9
1141	C:C:L41	C:C:N37	2.75	No	Yes	0	6	3
1142	P:P:L41	P:P:N37	2.75	No	No	0	6	3
1143	S:S:N106	S:S:N176	2.72	No	No	0	3	4
1144	C:C:N106	C:C:N176	2.72	No	No	0	3	4
1145	P:P:N106	P:P:N176	2.72	No	No	0	3	4
1146	S:S:D74	S:S:L69	2.71	No	No	0	8	6
1147	R:R:K230	R:R:Q233	2.71	No	No	0	5	5
1148	M:M:E36	S:S:K25	2.7	No	No	0	6	4
1149	R:R:E153	R:R:K154	2.7	No	No	0	7	3
1150	C:C:K25	Q:Q:E36	2.7	No	No	0	4	6
1151	P:P:K25	U:U:E36	2.7	No	No	0	4	6
1152	P:P:E268	P:P:K271	2.7	No	No	0	2	3
1153	S:S:A95	S:S:Y45	2.67	No	Yes	0	7	7
1154	R:R:A95	R:R:Y45	2.67	No	Yes	0	7	7
1155	R:R:A100	R:R:Y103	2.67	No	No	0	5	3
1156	C:C:A95	C:C:Y45	2.67	No	Yes	0	7	7
1157	P:P:A95	P:P:Y45	2.67	No	Yes	0	7	7
1158	S:S:F264	S:S:S260	2.64	No	No	0	4	5
1159	R:R:F201	R:R:S263	2.64	No	No	0	4	5
1160	R:R:F264	R:R:S260	2.64	No	No	0	4	5
1161	C:C:F264	C:C:S260	2.64	No	No	0	4	5
1162	P:P:F264	P:P:S260	2.64	No	No	0	4	5
1163	S:S:E31	S:S:N33	2.63	No	No	0	5	6
1164	R:R:F248	R:R:V124	2.62	Yes	No	0	9	7
1165	S:S:H140	S:S:N143	2.55	Yes	No	0	6	5
1166	C:C:H140	C:C:N143	2.55	Yes	No	0	6	5
1167	S:S:F40	S:S:I286	2.51	No	No	0	5	6
1168	S:S:F304	S:S:I300	2.51	No	No	0	6	6
1169	R:R:F40	R:R:I286	2.51	No	No	0	5	6
1170	R:R:I138	R:R:R235	2.51	No	No	0	8	5
1171	R:R:F304	R:R:I300	2.51	No	No	0	6	6
1172	C:C:F49	C:C:I53	2.51	Yes	No	0	6	5
1173	C:C:F264	C:C:I269	2.51	No	No	0	4	1
1174	C:C:F304	C:C:I300	2.51	No	No	0	6	6
1175	P:P:F304	P:P:I300	2.51	No	No	0	6	6
1176	S:S:T241	S:S:Y219	2.5	No	Yes	0	7	8
1177	C:C:T241	C:C:Y219	2.5	No	Yes	0	7	8
1178	P:P:T241	P:P:Y219	2.5	No	Yes	0	7	8
1179	M:M:F34	S:S:K25	2.48	No	No	0	6	4
1180	S:S:K236	S:S:R235	2.48	No	No	0	8	5
1181	C:C:K25	Q:Q:F34	2.48	No	No	13	4	6
1182	C:C:K236	C:C:R235	2.48	No	No	0	8	5
1183	C:C:K271	Q:Q:F34	2.48	Yes	No	13	3	6
1184	P:P:K25	U:U:F34	2.48	No	No	0	4	6
1185	P:P:K236	P:P:R235	2.48	No	No	0	8	5
1186	S:S:F107	S:S:L108	2.44	No	No	0	1	5
1187	S:S:F293	S:S:L290	2.44	Yes	No	0	5	7
1188	R:R:F49	R:R:L50	2.44	No	No	0	6	5
1189	R:R:F129	R:R:L151	2.44	Yes	No	0	5	4
1190	C:C:F107	C:C:L108	2.44	No	No	0	1	5
1191	P:P:F107	P:P:L108	2.44	No	No	0	1	5
1192	P:P:F293	P:P:L290	2.44	Yes	No	0	5	7
1193	S:S:L301	S:S:R77	2.43	No	No	0	7	8
1194	R:R:L301	R:R:R77	2.43	No	No	0	7	8
1195	C:C:L301	C:C:R77	2.43	No	No	0	7	8
1196	P:P:L301	P:P:R77	2.43	No	No	0	7	8
1197	S:S:F189	S:S:N176	2.42	Yes	No	0	3	4
1198	C:C:F189	C:C:N176	2.42	Yes	No	0	3	4
1199	P:P:F189	P:P:N176	2.42	Yes	No	0	3	4
1200	S:S:N278	S:S:R30	2.41	No	No	0	3	5
1201	R:R:N278	R:R:R30	2.41	No	No	0	3	5
1202	R:R:L41	R:R:Y45	2.34	No	Yes	0	6	7
1203	R:R:L61	R:R:Y65	2.34	No	No	0	4	5
1204	M:M:N54	M:M:Y28	2.33	No	Yes	0	8	8
1205	P:P:E275	P:P:F29	2.33	No	No	0	3	4
1206	U:U:F34	U:U:R33	2.14	No	No	0	6	9
1207	Y:Y:R29	Y:Y:R33	2.13	No	No	0	9	9
1208	P:P:Y190	U:U:Y28	1.99	Yes	Yes	3	4	8
1209	C:C:P27	Q:Q:P31	1.95	Yes	Yes	0	5	7
1210	P:P:P27	U:U:P31	1.95	Yes	Yes	0	5	7
1211	M:M:C71	S:S:P27	1.88	No	No	0	9	5
1212	M:M:P31	S:S:C28	1.88	No	No	0	7	9
1213	L:L:P31	R:R:C28	1.88	No	No	0	7	9
1214	M:M:C30	M:M:P31	1.88	No	No	0	9	7
1215	q:q:C30	q:q:P31	1.88	No	No	0	9	7
1216	P:P:C28	U:U:P31	1.88	No	Yes	0	9	7
1217	Y:Y:C30	Y:Y:P31	1.88	No	No	37	9	7
1218	Y:Y:C32	Y:Y:P31	1.88	No	No	37	9	7
1219	J:J:C30	J:J:P31	1.88	No	No	0	9	7
1220	N:N:C30	N:N:P31	1.88	No	No	0	9	7
1221	Q:Q:C30	Q:Q:P31	1.88	No	Yes	0	9	7
1222	U:U:C30	U:U:P31	1.88	No	Yes	0	9	7
1223	L:L:C30	L:L:P31	1.88	No	No	0	9	7
1224	S:S:A128	S:S:P211	1.87	No	No	0	7	9
1225	Q:Q:A86	q:q:P74	1.87	No	No	0	8	8
1226	C:C:A128	C:C:P211	1.87	No	No	0	7	9
1227	P:P:A128	P:P:P211	1.87	No	No	0	7	9
1228	S:S:G231	S:S:S229	1.86	No	No	0	4	5
1229	P:P:G231	P:P:S229	1.86	No	No	0	4	5
1230	S:S:G159	S:S:V158	1.84	No	No	0	3	4
1231	R:R:G52	R:R:V88	1.84	No	No	0	8	6
1232	C:C:G52	C:C:V88	1.84	No	No	0	8	6
1233	C:C:G159	C:C:V158	1.84	No	No	0	3	4
1234	P:P:G52	P:P:V88	1.84	No	No	0	8	6
1235	P:P:G159	P:P:V158	1.84	No	No	0	3	4
1236	M:M:A56	M:M:C55	1.81	No	No	0	6	9
1237	Y:Y:A56	Y:Y:C32	1.81	No	No	0	6	9
1238	J:J:A56	J:J:C32	1.81	No	No	0	6	9
1239	Q:Q:A56	Q:Q:C32	1.81	No	No	0	6	9
1240	C:C:P27	Q:Q:V60	1.77	Yes	No	0	5	8
1241	P:P:P27	U:U:V60	1.77	Yes	No	0	5	8
1242	R:R:G64	R:R:M63	1.75	No	Yes	0	2	6
1243	S:S:A164	S:S:S122	1.71	No	Yes	0	7	7
1244	S:S:A180	S:S:S178	1.71	No	No	0	1	1
1245	R:R:A164	R:R:S122	1.71	No	Yes	0	7	7
1246	R:R:C218	R:R:V214	1.71	No	No	0	6	6
1247	R:R:G306	R:R:L301	1.71	No	No	0	8	7
1248	C:C:A164	C:C:S122	1.71	No	Yes	0	7	7
1249	C:C:A180	C:C:S178	1.71	No	No	0	1	1
1250	C:C:C218	C:C:V214	1.71	Yes	No	0	6	6
1251	P:P:A164	P:P:S122	1.71	No	Yes	0	7	7
1252	P:P:A180	P:P:S178	1.71	No	No	0	1	1
1253	P:P:C218	P:P:V214	1.71	No	No	0	6	6
1254	L:L:C71	L:L:V60	1.71	No	No	0	9	8
1255	S:S:A100	S:S:V96	1.7	No	No	0	5	5
1256	S:S:A164	S:S:V118	1.7	No	No	0	7	5
1257	M:M:A61	M:M:V44	1.7	No	No	0	9	7
1258	C:C:G52	C:C:N56	1.7	No	Yes	0	8	9
1259	C:C:A100	C:C:V96	1.7	No	No	0	5	5
1260	P:P:A100	P:P:V96	1.7	No	No	0	5	5
1261	Q:Q:A61	Q:Q:V44	1.7	No	No	0	9	7
1262	q:q:K22	q:q:P23	1.67	No	No	0	9	9
1263	Y:Y:K22	Y:Y:P23	1.67	No	No	0	9	9
1264	J:J:K22	J:J:P23	1.67	No	No	0	9	9
1265	N:N:K22	N:N:P23	1.67	No	No	0	9	9
1266	S:S:L210	S:S:P211	1.64	No	No	0	6	9
1267	S:S:G273	S:S:Q272	1.64	No	No	0	5	2
1268	S:S:C296	S:S:I300	1.64	No	No	0	7	6
1269	R:R:L210	R:R:P211	1.64	No	No	0	6	9
1270	R:R:C296	R:R:I300	1.64	No	No	0	7	6
1271	q:q:L57	q:q:P74	1.64	No	No	0	7	8
1272	C:C:L210	C:C:P211	1.64	No	No	0	6	9
1273	C:C:C296	C:C:I300	1.64	No	No	0	7	6
1274	P:P:L210	P:P:P211	1.64	No	No	0	6	9
1275	P:P:C296	P:P:I300	1.64	No	No	0	7	6
1276	Y:Y:L57	Y:Y:P74	1.64	No	No	0	7	8
1277	N:N:L57	N:N:P74	1.64	No	No	0	7	8
1278	S:S:A289	S:S:I44	1.62	No	No	0	4	5
1279	R:R:A180	R:R:I185	1.62	No	No	0	1	3
1280	C:C:S263	C:C:V197	1.62	No	No	0	5	3
1281	S:S:V155	S:S:V158	1.6	No	No	0	2	4
1282	C:C:V155	C:C:V158	1.6	No	No	0	2	4
1283	P:P:V155	P:P:V158	1.6	No	No	0	2	4
1284	R:R:C220	S:S:L58	1.59	No	No	0	3	5
1285	P:P:L58	S:S:C220	1.59	No	No	0	5	3
1286	S:S:C251	S:S:L297	1.59	No	No	0	8	6
1287	C:C:C220	R:R:L58	1.59	No	No	0	3	5
1288	R:R:T168	R:R:V114	1.59	No	No	0	6	5
1289	R:R:G231	R:R:H232	1.59	No	No	0	4	4
1290	C:C:L58	P:P:C220	1.59	No	No	0	5	3
1291	C:C:T168	C:C:V118	1.59	No	No	0	6	5
1292	C:C:C218	C:C:L132	1.59	Yes	No	0	6	6
1293	C:C:C251	C:C:L297	1.59	No	No	0	8	6
1294	P:P:T168	P:P:V118	1.59	Yes	No	0	6	5
1295	P:P:C251	P:P:L297	1.59	No	No	0	8	6
1296	L:L:Q69	R:R:P27	1.58	No	No	0	9	5
1297	M:M:A61	M:M:L47	1.58	No	No	0	9	9
1298	J:J:A86	M:M:L57	1.58	No	No	0	8	7
1299	J:J:L57	M:M:A86	1.58	No	No	0	7	8
1300	q:q:A61	q:q:L47	1.58	No	No	0	9	9
1301	Q:Q:L57	q:q:A86	1.58	No	No	0	7	8
1302	Y:Y:P31	Y:Y:Q58	1.58	No	No	0	7	9
1303	Y:Y:A61	Y:Y:L47	1.58	No	No	0	9	9
1304	U:U:A86	Y:Y:L57	1.58	No	No	0	8	7
1305	U:U:L57	Y:Y:A86	1.58	No	No	0	7	8
1306	J:J:P31	J:J:Q58	1.58	No	No	0	7	9
1307	J:J:A61	J:J:L47	1.58	No	No	0	9	9
1308	N:N:A61	N:N:L47	1.58	No	No	0	9	9
1309	L:L:A86	N:N:L57	1.58	No	No	0	8	7
1310	L:L:L57	N:N:A86	1.58	No	No	0	7	8
1311	Q:Q:A61	Q:Q:L47	1.58	No	No	0	9	9
1312	U:U:P31	U:U:Q58	1.58	Yes	No	0	7	9
1313	U:U:A61	U:U:L47	1.58	No	No	0	9	9
1314	L:L:A61	L:L:L47	1.58	No	No	0	9	9
1315	R:R:E26	R:R:P27	1.57	No	No	0	2	5
1316	M:M:A40	M:M:N43	1.56	No	No	0	5	5
1317	q:q:A40	q:q:N43	1.56	No	No	0	5	5
1318	P:P:A34	P:P:N37	1.56	No	No	0	1	3
1319	Y:Y:A40	Y:Y:N43	1.56	No	No	0	5	5
1320	J:J:A40	J:J:N43	1.56	No	No	0	5	5
1321	N:N:A40	N:N:N43	1.56	No	No	0	5	5
1322	Q:Q:A40	Q:Q:N43	1.56	No	No	0	5	5
1323	U:U:A40	U:U:N43	1.56	No	No	0	5	5
1324	L:L:A40	L:L:N43	1.56	No	No	0	5	5
1325	S:S:I213	S:S:S217	1.55	No	No	0	3	3
1326	R:R:I213	R:R:S217	1.55	No	No	0	3	3
1327	C:C:I60	C:C:S81	1.55	Yes	Yes	0	7	9
1328	C:C:I213	C:C:S217	1.55	No	No	0	3	3
1329	P:P:I60	P:P:S81	1.55	Yes	Yes	0	7	9
1330	P:P:I213	P:P:S217	1.55	No	No	0	3	3
1331	R:R:I223	S:S:V62	1.54	No	Yes	0	4	7
1332	P:P:V62	S:S:I223	1.54	No	No	0	7	4
1333	C:C:I223	R:R:V62	1.54	No	No	0	4	7
1334	R:R:A180	R:R:D182	1.54	No	No	0	1	6
1335	C:C:V62	P:P:I223	1.54	No	No	0	7	4
1336	S:S:K225	S:S:S224	1.53	No	No	0	4	4
1337	M:M:C32	M:M:Q58	1.53	No	No	0	9	9
1338	C:C:K68	P:P:S227	1.53	No	No	0	6	4
1339	C:C:K225	C:C:S224	1.53	No	No	0	4	4
1340	P:P:K225	P:P:S224	1.53	No	No	0	4	4
1341	R:R:K68	R:R:V62	1.52	No	No	0	6	7
1342	M:M:C71	M:M:E36	1.52	No	No	0	9	6
1343	C:C:C274	C:C:E26	1.52	No	No	0	5	2
1344	R:R:F104	R:R:G105	1.51	Yes	No	0	7	8
1345	C:C:F276	C:C:G273	1.51	Yes	No	0	1	5
1346	Y:Y:L26	Y:Y:S27	1.5	No	No	0	9	6
1347	N:N:L26	N:N:S27	1.5	No	No	0	9	6
1348	S:S:N37	S:S:S285	1.49	No	No	0	3	5
1349	S:S:L194	S:S:V198	1.49	No	No	0	2	3
1350	R:R:L165	R:R:V118	1.49	No	No	0	3	5
1351	R:R:L150	R:R:V155	1.49	No	No	0	4	2
1352	R:R:L246	R:R:V242	1.49	No	No	0	5	4
1353	M:M:L26	M:M:V24	1.49	No	Yes	0	9	7
1354	C:C:L165	C:C:V118	1.49	No	No	0	3	5
1355	C:C:L194	C:C:V198	1.49	No	No	0	2	3
1356	P:P:L165	P:P:V118	1.49	No	No	0	3	5
1357	P:P:L194	P:P:V198	1.49	No	No	0	2	3
1358	S:S:N106	S:S:V177	1.48	No	No	0	3	4
1359	S:S:I209	S:S:I213	1.47	No	No	0	4	3
1360	R:R:I209	R:R:I213	1.47	No	No	0	4	3
1361	M:M:I49	M:M:I59	1.47	No	No	0	9	9
1362	C:C:I209	C:C:I213	1.47	No	No	0	4	3
1363	P:P:I209	P:P:I213	1.47	No	No	0	4	3
1364	Q:Q:I49	Q:Q:I59	1.47	No	No	0	9	9
1365	L:L:I59	L:L:I72	1.47	No	No	0	9	6
1366	S:S:D193	S:S:V196	1.46	No	No	0	1	4
1367	R:R:D193	R:R:V196	1.46	No	No	0	1	4
1368	P:P:I138	P:P:K234	1.45	No	No	0	8	7
1369	M:M:R33	S:S:P27	1.44	No	No	0	9	5
1370	R:R:S224	S:S:Q66	1.44	No	No	0	4	4
1371	P:P:Q66	S:S:S224	1.44	Yes	No	0	4	4
1372	R:R:P147	R:R:R146	1.44	No	No	0	4	5
1373	J:J:K48	M:M:K48	1.44	No	No	0	7	7
1374	Q:Q:K48	q:q:K48	1.44	No	No	0	7	7
1375	U:U:K48	Y:Y:K48	1.44	No	No	0	7	7
1376	S:S:I60	S:S:L78	1.43	No	No	0	7	5
1377	R:R:I162	R:R:L166	1.43	No	No	0	4	4
1378	R:R:I286	R:R:L290	1.43	No	No	0	6	7
1379	M:M:I79	M:M:L76	1.43	No	No	0	8	6
1380	q:q:I79	q:q:L76	1.43	No	No	0	8	6
1381	C:C:I44	C:C:L290	1.43	No	No	0	5	7
1382	C:C:I60	C:C:L78	1.43	Yes	No	0	7	5
1383	P:P:I60	P:P:L78	1.43	Yes	No	0	7	5
1384	Y:Y:I79	Y:Y:L76	1.43	No	No	0	8	6
1385	J:J:I79	J:J:L76	1.43	No	No	0	8	6
1386	N:N:I79	N:N:L76	1.43	No	No	0	8	6
1387	Q:Q:I79	Q:Q:L76	1.43	No	No	0	8	6
1388	U:U:I79	U:U:L76	1.43	No	No	0	8	6
1389	L:L:I79	L:L:L76	1.43	No	No	0	8	6
1390	S:S:K154	S:S:L150	1.41	No	No	0	3	4
1391	J:J:L57	M:M:K85	1.41	No	No	0	7	7
1392	P:P:K154	P:P:L150	1.41	No	No	0	3	4
1393	L:L:K85	N:N:L57	1.41	No	No	0	7	7
1394	S:S:C251	S:S:F293	1.4	No	Yes	0	8	5
1395	R:R:C251	R:R:F293	1.4	No	No	0	8	5
1396	q:q:C71	q:q:F34	1.4	No	No	0	9	6
1397	C:C:C251	C:C:F293	1.4	No	No	0	8	5
1398	P:P:C251	P:P:F293	1.4	No	Yes	0	8	5
1399	Y:Y:C71	Y:Y:F34	1.4	No	No	0	9	6
1400	J:J:C71	J:J:F34	1.4	No	No	0	9	6
1401	N:N:C71	N:N:F34	1.4	No	No	0	9	6
1402	S:S:L132	S:S:L136	1.38	No	No	0	6	5
1403	S:S:L132	S:S:L151	1.38	No	No	0	6	4
1404	S:S:A237	S:S:R134	1.38	No	No	0	7	9
1405	R:R:A237	R:R:R134	1.38	No	No	0	7	9
1406	R:R:L226	R:R:L238	1.38	No	No	0	8	5
1407	C:C:A237	C:C:R134	1.38	No	Yes	0	7	9
1408	C:C:L244	C:C:L297	1.38	No	No	0	7	6
1409	P:P:A237	P:P:R134	1.38	No	No	0	7	9
1410	q:q:N43	q:q:N65	1.36	No	No	0	5	4
1411	Y:Y:N43	Y:Y:N65	1.36	No	No	0	5	4
1412	J:J:N43	J:J:N65	1.36	No	No	0	5	4
1413	N:N:N43	N:N:N65	1.36	No	No	0	5	4
1414	L:L:D73	L:L:L76	1.36	No	No	0	8	6
1415	P:P:E153	P:P:K154	1.35	No	No	0	7	3
1416	L:L:C55	L:L:Y28	1.34	No	No	0	9	8
1417	S:S:D181	S:S:D182	1.33	No	No	0	2	6
1418	M:M:L50	M:M:Q58	1.33	No	No	0	5	9
1419	q:q:L50	q:q:Q58	1.33	No	No	0	5	9
1420	Y:Y:L50	Y:Y:Q58	1.33	No	No	0	5	9
1421	J:J:L50	J:J:Q58	1.33	No	No	0	5	9
1422	N:N:L50	N:N:Q58	1.33	No	No	0	5	9
1423	Q:Q:L50	Q:Q:Q58	1.33	No	No	0	5	9
1424	U:U:L50	U:U:Q58	1.33	No	No	0	5	9
1425	L:L:L50	L:L:Q58	1.33	No	No	0	5	9
1426	J:J:K48	M:M:H46	1.31	No	No	0	7	8
1427	J:J:H46	M:M:K48	1.31	No	No	0	8	7
1428	Q:Q:K48	q:q:H46	1.31	No	No	0	7	8
1429	Q:Q:H46	q:q:K48	1.31	No	No	0	8	7
1430	C:C:H232	C:C:K230	1.31	No	No	0	4	5
1431	P:P:H232	P:P:K230	1.31	No	No	0	4	5
1432	U:U:K48	Y:Y:H46	1.31	No	No	0	7	8
1433	U:U:H46	Y:Y:K48	1.31	No	No	0	8	7
1434	L:L:K48	N:N:H46	1.31	No	No	0	7	8
1435	L:L:H46	N:N:K48	1.31	No	No	0	8	7
1436	J:J:H46	M:M:L50	1.29	No	No	0	8	5
1437	L:L:L50	N:N:H46	1.29	No	No	0	5	8
1438	R:R:H140	R:R:N143	1.28	No	No	0	6	5
1439	P:P:H140	P:P:N143	1.28	Yes	No	0	6	5
1440	S:S:V177	S:S:Y184	1.26	No	No	0	4	5
1441	C:C:V177	C:C:Y184	1.26	No	No	0	4	5
1442	P:P:V177	P:P:Y184	1.26	No	No	0	4	5
1443	S:S:K239	S:S:R235	1.24	No	No	0	6	5
1444	L:L:R33	R:R:K271	1.24	No	No	0	9	3
1445	q:q:K45	q:q:R62	1.24	No	No	0	7	6
1446	C:C:K239	C:C:R235	1.24	No	No	0	6	5
1447	P:P:K239	P:P:R235	1.24	No	No	0	6	5
1448	Y:Y:K45	Y:Y:R62	1.24	No	No	0	7	6
1449	J:J:K45	J:J:R62	1.24	No	No	0	7	6
1450	N:N:K45	N:N:R62	1.24	No	No	0	7	6
1451	L:L:N54	R:R:F189	1.21	No	No	0	8	3
1452	M:M:D73	M:M:F35	1.19	No	No	0	8	6
1453	q:q:D73	q:q:F35	1.19	No	No	0	8	6
1454	Y:Y:D73	Y:Y:F35	1.19	No	No	0	8	6
1455	J:J:D73	J:J:F35	1.19	No	No	0	8	6
1456	N:N:D73	N:N:F35	1.19	No	No	0	8	6
1457	Q:Q:D73	Q:Q:F35	1.19	No	No	0	8	6
1458	U:U:D73	U:U:F35	1.19	No	No	0	8	6
1459	L:L:D73	L:L:F35	1.19	No	No	0	8	6
1460	C:C:Q272	R:R:R183	1.17	No	Yes	0	2	3
1461	J:J:N51	M:M:Y82	1.16	No	No	0	7	8
1462	q:q:N54	q:q:Y28	1.16	No	No	0	8	8
1463	Q:Q:Y82	q:q:N51	1.16	No	No	0	8	7
1464	Y:Y:N54	Y:Y:Y28	1.16	No	No	0	8	8
1465	U:U:Y82	Y:Y:N51	1.16	No	No	0	8	7
1466	J:J:N54	J:J:Y28	1.16	No	No	0	8	8
1467	N:N:N54	N:N:Y28	1.16	No	No	0	8	8
1468	L:L:Y82	N:N:N51	1.16	No	No	0	8	7
1469	P:P:Q66	P:P:Y65	1.13	Yes	No	0	4	5
1470	L:L:H46	L:L:R62	1.13	No	No	0	8	6
1471	M:M:R41	M:M:W78	1	No	No	0	6	8
1472	q:q:R41	q:q:W78	1	No	No	0	6	8
1473	Y:Y:R41	Y:Y:W78	1	No	No	0	6	8
1474	J:J:R41	J:J:W78	1	No	No	0	6	8
1475	N:N:R41	N:N:W78	1	No	No	0	6	8
1476	Q:Q:R41	Q:Q:W78	1	No	No	0	6	8
1477	U:U:R41	U:U:W78	1	No	No	0	6	8
1478	L:L:R41	L:L:W78	1	No	No	0	6	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	S:S:N35	4.836	5	0	3
2	S:S:Y45	4.3325	4	0	7
3	S:S:N56	5.3825	4	0	9
4	S:S:V62	3.85	4	16	7
5	S:S:K68	5.58	4	16	6
6	S:S:Y76	4.93	5	18	7
7	S:S:F87	9.175	4	1	7
8	S:S:W94	6.542	5	1	7
9	S:S:W102	9.648	5	1	9
10	S:S:V112	5.33	4	0	5
11	S:S:H113	4.95833	6	1	6
12	S:S:Y116	6.2	4	1	6
13	S:S:L120	4.4075	4	1	7
14	S:S:Y121	7.22	4	1	7
15	S:S:S122	4.87	4	19	7
16	S:S:I126	5.105	4	0	7
17	S:S:S131	6.5	4	14	9
18	S:S:Y135	4.5975	4	20	8
19	S:S:H140	5.1875	4	20	6
20	S:S:R148	6.4475	4	17	6
21	S:S:V160	4.7775	4	19	7
22	S:S:D171	7.84	4	0	4
23	S:S:F174	6.6625	4	1	4
24	S:S:D187	5.765	4	0	3
25	S:S:F189	4.81	4	0	3
26	S:S:Y190	6.76714	7	1	4
27	S:S:W195	5.4375	4	1	5
28	S:S:F199	7.73	4	1	5
29	S:S:Q202	5.2275	4	1	3
30	S:S:H203	8.956	5	1	4
31	S:S:Y219	5.49	5	14	8
32	S:S:I245	3.5	4	14	7
33	S:S:F248	6.655	6	1	9
34	S:S:W252	8.136	5	1	9
35	S:S:Y255	6.27667	6	1	7
36	S:S:Y256	6.352	5	1	8
37	S:S:I259	6.002	5	1	5
38	S:S:I265	4.1675	4	6	3
39	S:S:F276	4.4	4	6	1
40	S:S:V280	4.325	4	6	5
41	S:S:W283	7.16	5	6	6
42	S:S:F292	8.4825	4	1	7
43	S:S:F293	6.4725	4	0	5
44	S:S:H294	7.734	5	1	9
45	S:S:N298	4.9175	4	0	9
46	S:S:P299	4.3425	4	0	9
47	R:R:Y45	4.0575	4	0	7
48	R:R:I48	3.52	4	0	7
49	R:R:M63	5.025	4	11	6
50	R:R:Y76	5.23	5	0	7
51	R:R:F87	8.4725	4	2	7
52	R:R:F93	5.905	4	5	6
53	R:R:W94	7.68	4	0	7
54	R:R:W102	8.16143	7	5	9
55	R:R:F104	7.336	5	5	7
56	R:R:C109	4.3925	4	5	9
57	R:R:V112	5.655	4	5	5
58	R:R:H113	4.444	5	5	6
59	R:R:Y116	4.81	5	2	6
60	R:R:T117	6.21	4	0	5
61	R:R:L120	4.125	4	2	7
62	R:R:Y121	5.824	5	2	7
63	R:R:S122	4.87	4	12	7
64	R:R:F129	3.705	4	0	5
65	R:R:R148	7.1975	4	25	6
66	R:R:V160	4.796	5	12	7
67	R:R:W161	5.52	4	12	9
68	R:R:F174	8.0975	4	2	4
69	R:R:V177	4.515	4	5	4
70	R:R:R183	7.5525	4	0	3
71	R:R:R188	7.705	4	0	5
72	R:R:Y190	10.106	5	2	4
73	R:R:W195	4.156	5	2	5
74	R:R:F199	7.995	4	2	5
75	R:R:H203	9.26	5	2	4
76	R:R:Y219	4.728	5	0	8
77	R:R:T241	4.3975	4	0	7
78	R:R:F248	6.61333	6	2	9
79	R:R:W252	7.898	5	2	9
80	R:R:Y255	6.08833	6	2	7
81	R:R:Y256	6.856	5	2	8
82	R:R:I259	5.696	5	2	5
83	R:R:D262	6.6575	4	0	5
84	R:R:W283	8.54	4	10	6
85	R:R:H294	7.8425	4	2	9
86	R:R:N298	6.48	4	11	9
87	R:R:Y302	9.6125	4	11	9
88	M:M:K22	9.05	4	1	9
89	M:M:V24	4.9175	4	1	7
90	M:M:Y28	4.92	4	0	8
91	M:M:R29	4.545	4	0	9
92	C:C:P27	3.8375	4	0	5
93	C:C:N37	3.2775	4	0	3
94	C:C:I39	5.4575	4	7	5
95	C:C:Y45	4.625	4	0	7
96	C:C:F49	4.2575	4	0	6
97	C:C:N56	4.785	4	0	9
98	C:C:I60	2.5825	4	0	7
99	C:C:Y76	5.656	5	29	7
100	C:C:S81	4.2375	4	0	9
101	C:C:D84	6.3825	4	27	9
102	C:C:F87	7.938	5	4	7
103	C:C:W94	6.766	5	0	7
104	C:C:W102	10.132	5	15	9
105	C:C:C109	4.3925	4	15	9
106	C:C:V112	6.03	4	0	5
107	C:C:H113	4.336	5	15	6
108	C:C:Y116	6.2	4	4	6
109	C:C:L120	4.4475	4	4	7
110	C:C:Y121	7.22	4	4	7
111	C:C:S122	4.87	4	9	7
112	C:C:R134	3.4975	4	28	9
113	C:C:Y135	5.5225	4	30	8
114	C:C:H140	4.8475	4	30	6
115	C:C:R148	6.7575	4	28	6
116	C:C:V160	4.7775	4	9	7
117	C:C:W161	5.465	4	9	9
118	C:C:P170	4.4575	4	0	8
119	C:C:D171	6.775	4	0	4
120	C:C:F174	7.605	4	4	4
121	C:C:D187	5.1	4	0	3
122	C:C:R188	8.4475	4	0	5
123	C:C:F189	5.4	4	0	3
124	C:C:Y190	7.18429	7	4	4
125	C:C:W195	5.4475	4	4	5
126	C:C:F199	7.7225	4	4	5
127	C:C:Q200	4.93	4	0	5
128	C:C:H203	8.778	5	4	4
129	C:C:C218	3.03	4	0	6
130	C:C:Y219	4.32	4	0	8
131	C:C:F248	7.36	6	4	9
132	C:C:W252	7.55833	6	4	9
133	C:C:Y255	6.68833	6	4	7
134	C:C:Y256	5.81833	6	4	8
135	C:C:I259	5.348	5	4	5
136	C:C:I265	4.225	4	22	3
137	C:C:K271	3.2775	4	13	3
138	C:C:F276	3.56	4	22	1
139	C:C:V280	4.325	4	22	5
140	C:C:H281	8.92	4	0	4
141	C:C:W283	7.16	5	0	6
142	C:C:F292	8.4825	4	4	7
143	C:C:H294	7.522	5	4	9
144	C:C:N298	5.534	5	27	9
145	C:C:P299	4.3425	4	0	9
146	P:P:P27	4.3075	4	0	5
147	P:P:E31	6.57	4	31	5
148	P:P:N35	4.35	4	0	3
149	P:P:I39	5.4575	4	6	5
150	P:P:Y45	4.198	5	0	7
151	P:P:I60	2.225	4	0	7
152	P:P:Q66	4.6625	4	0	4
153	P:P:Y76	5.198	5	33	7
154	P:P:S81	4.6425	4	0	9
155	P:P:F87	10.0475	4	8	7
156	P:P:W94	6.754	5	8	7
157	P:P:W102	10.814	5	8	9
158	P:P:C109	4.3925	4	8	9
159	P:P:V112	5.635	4	0	5
160	P:P:H113	5.11833	6	8	6
161	P:P:Y121	7.22	4	3	7
162	P:P:S122	4.87	4	34	7
163	P:P:I126	5.105	4	0	7
164	P:P:Y135	5.25	4	36	8
165	P:P:H140	4.87	4	36	6
166	P:P:V160	4.7775	4	34	7
167	P:P:T168	3.345	4	35	6
168	P:P:D171	7.3875	4	0	4
169	P:P:F174	4.715	4	3	4
170	P:P:D187	5.07	4	3	3
171	P:P:R188	7.39	4	0	5
172	P:P:F189	4.625	4	3	3
173	P:P:Y190	6.59286	7	3	4
174	P:P:W195	5.6875	4	3	5
175	P:P:F199	7.9875	4	3	5
176	P:P:Q202	5.2275	4	3	3
177	P:P:H203	8.69	5	3	4
178	P:P:Y219	4.32	4	0	8
179	P:P:F248	6.655	6	3	9
180	P:P:W252	7.89	5	3	9
181	P:P:Y255	5.92143	7	3	7
182	P:P:Y256	6.388	5	3	8
183	P:P:I259	5.872	5	3	5
184	P:P:I265	4.4825	4	7	3
185	P:P:E277	7.7775	4	7	2
186	P:P:V280	4.6525	4	7	5
187	P:P:H281	8.48	4	7	4
188	P:P:W283	7.16	5	7	6
189	P:P:F292	8.235	4	8	7
190	P:P:F293	5.8125	4	0	5
191	P:P:H294	7.522	5	3	9
192	P:P:N298	4.9175	4	0	9
193	P:P:P299	4.3425	4	0	9
194	Q:Q:P31	3.63	4	0	7
195	U:U:K22	8.655	4	8	9
196	U:U:P23	6.5875	4	3	9
197	U:U:Y28	4.4375	4	3	8
198	U:U:R29	5.09	4	7	9
199	U:U:P31	1.8225	4	0	7
200	L:L:V24	4.965	4	2	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	P:P:I39	S:S:V280	97.7914	3.07	Yes	Yes	6	5	5
2	P:P:F36	P:P:I39	97.8362	3.77	No	Yes	6	4	5
3	P:P:F36	P:P:F40	98.9917	8.57	No	No	0	4	5
4	P:P:F40	P:P:I44	99.0765	6.28	No	No	0	5	5
5	P:P:I44	P:P:I48	99.1611	2.94	No	No	0	5	7
6	P:P:I48	P:P:L91	100	2.85	No	No	0	7	8
7	P:P:L91	P:P:Y45	49.4282	3.52	No	Yes	0	8	7
8	P:P:F292	P:P:Y45	45.1368	7.22	Yes	Yes	0	7	7
9	P:P:E288	P:P:F292	89.5973	3.5	No	Yes	0	5	7
10	P:P:E288	P:P:Y255	92.0433	5.61	No	Yes	0	5	7
11	P:P:Y255	P:P:Y256	89.7704	3.97	Yes	Yes	3	7	8
12	P:P:L208	P:P:Y256	93.8016	10.55	No	Yes	0	8	8
13	P:P:L208	P:P:L253	93.7331	2.77	No	No	0	8	5
14	C:C:L50	P:P:L253	93.5957	2.77	No	No	0	5	5
15	C:C:F49	C:C:L50	93.5282	3.65	Yes	No	0	6	5
16	C:C:F49	C:C:L91	93.342	3.65	Yes	No	0	6	8
17	C:C:F87	C:C:L91	97.0563	3.65	Yes	No	0	7	8
18	C:C:F292	C:C:F87	59.3098	13.93	Yes	Yes	4	7	7
19	C:C:E288	C:C:F292	51.6716	3.5	No	Yes	0	5	7
20	C:C:E288	C:C:Y255	52.2753	6.73	No	Yes	0	5	7
21	C:C:Y255	Q:Q:V24	55.3661	7.57	Yes	No	4	7	7
22	C:C:Q200	Q:Q:V24	55.4859	8.6	Yes	No	0	5	7
23	C:C:D262	C:C:Q200	55.0263	3.92	No	Yes	0	5	5
24	C:C:D262	C:C:V280	51.5274	4.38	No	Yes	0	5	5
25	C:C:V280	R:R:I39	50.7064	3.07	Yes	No	0	5	5
26	C:C:W283	R:R:I39	50.1386	10.57	Yes	No	0	6	5
27	C:C:W283	R:R:F36	49.1812	3.01	Yes	No	0	6	4
28	R:R:F36	R:R:F40	49.0609	9.65	No	No	0	4	5
29	R:R:F40	R:R:I44	47.7291	10.05	No	No	0	5	5
30	R:R:I44	R:R:I48	47.6073	2.94	No	Yes	0	5	7
31	R:R:I48	R:R:L91	41.3014	2.85	Yes	No	0	7	8
32	R:R:F87	R:R:L91	41.1732	3.65	Yes	No	0	7	8
33	R:R:F87	R:R:Y116	27.1249	5.16	Yes	Yes	2	7	6
34	P:P:F87	P:P:L91	50.9725	3.65	Yes	No	0	7	8
35	P:P:F292	P:P:F87	44.7627	15	Yes	Yes	8	7	7
36	M:M:V24	S:S:Q200	42.6139	5.73	Yes	No	0	7	5
37	S:S:D262	S:S:Q200	43.1964	5.22	No	No	0	5	5
38	S:S:D262	S:S:V280	93.3858	4.38	No	Yes	0	5	5
39	M:M:V24	S:S:Y255	39.5722	6.31	Yes	Yes	1	7	7
40	S:S:E288	S:S:Y255	21.4269	5.61	No	Yes	0	5	7
41	S:S:D262	S:S:I284	50.0968	4.2	No	No	0	5	4
42	S:S:I259	S:S:I284	49.9838	5.89	Yes	No	0	5	4
43	S:S:I259	S:S:Y255	39.3885	8.46	Yes	Yes	1	5	7
44	M:M:K22	S:S:E288	15.5745	10.8	Yes	No	0	9	5
45	S:S:W252	S:S:Y255	39.6893	5.79	Yes	Yes	1	9	7
46	S:S:H294	S:S:W252	25.8902	12.7	Yes	Yes	1	9	9
47	S:S:C295	S:S:H294	25.7059	7.37	No	Yes	0	9	9
48	S:S:C295	S:S:D84	24.5423	7.78	No	No	0	9	9
49	S:S:D84	S:S:L80	20.4187	4.07	No	No	0	9	9
50	S:S:I126	S:S:L80	10.4902	4.28	Yes	No	0	7	9
51	S:S:H203	S:S:Y255	18.7978	6.53	Yes	Yes	1	4	7
52	S:S:I259	S:S:Y256	10.3791	3.63	Yes	Yes	1	5	8
53	S:S:H203	S:S:Y121	16.272	5.44	Yes	Yes	1	4	7
54	S:S:Q202	S:S:Y121	14.9464	6.76	Yes	Yes	1	3	7
55	S:S:F199	S:S:Q202	14.5186	5.86	Yes	Yes	1	5	3
56	M:M:P23	S:S:H203	10.8185	16.78	No	Yes	1	9	4
57	M:M:P23	S:S:T117	10.7135	3.5	No	No	0	9	5
58	S:S:D171	S:S:R188	12.872	13.1	Yes	No	0	4	5
59	S:S:D187	S:S:R188	12.0157	4.76	Yes	No	0	3	5
60	S:S:F248	S:S:W252	13.5557	10.02	Yes	Yes	1	9	9
61	S:S:F248	S:S:L127	10.295	6.09	Yes	No	0	9	8
62	L:L:K22	R:R:W94	13.7932	11.6	No	Yes	0	9	7
63	L:L:K22	R:R:Y116	13.3151	4.78	No	Yes	2	9	6
64	C:C:F87	C:C:Y116	15.3977	8.25	Yes	Yes	4	7	6
65	C:C:C295	C:C:F87	17.6978	4.19	No	Yes	0	9	7
66	C:C:F248	C:C:H294	10.545	7.92	Yes	Yes	4	9	9
67	R:R:I245	R:R:Y219	10.6008	3.63	No	Yes	0	7	8
68	R:R:I245	R:R:L127	12.5496	7.14	No	No	0	7	8
69	R:R:F248	R:R:L127	13.1762	6.09	Yes	No	0	9	8
70	R:R:F248	R:R:H294	12.5107	9.05	Yes	Yes	2	9	9
71	R:R:H294	R:R:N119	13.1025	5.1	Yes	No	0	9	8
72	R:R:F87	R:R:N119	13.2448	13.29	Yes	No	0	7	8
73	C:C:C295	C:C:D84	14.4458	9.34	No	Yes	0	9	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
C:C:K25	C:C:K271	2.87	13	No	Yes	4	3	1	1
C:C:E26	C:C:P27	7.86	0	No	Yes	2	5	2	1
C:C:P27	Q:Q:C71	3.77	0	Yes	No	5	9	1	0
C:C:C28	Q:Q:P31	7.53	0	No	Yes	9	7	1	0
C:C:R30	Q:Q:R29	19.19	0	No	No	5	9	1	0
C:C:E31	C:C:N278	9.2	0	No	No	5	3	2	1
C:C:W94	C:C:Y45	2.89	0	Yes	Yes	7	7	1	2
C:C:F292	C:C:Y45	8.25	4	Yes	Yes	7	7	2	2
C:C:F87	C:C:Y116	8.25	4	Yes	Yes	7	6	2	1
C:C:F292	C:C:F87	13.93	4	Yes	Yes	7	7	2	2
C:C:D97	C:C:W94	4.47	0	No	Yes	5	7	2	1
C:C:V112	C:C:W94	7.36	0	Yes	Yes	5	7	2	1
C:C:H113	C:C:W94	6.35	15	Yes	Yes	6	7	2	1
C:C:W94	Q:Q:K22	12.76	0	Yes	No	7	9	1	0
C:C:D171	C:C:H113	5.04	0	Yes	Yes	4	6	2	2
C:C:L120	C:C:Y116	3.52	4	Yes	Yes	7	6	1	1
C:C:F292	C:C:Y116	8.25	4	Yes	Yes	7	6	2	1
C:C:Y116	Q:Q:K22	4.78	4	Yes	No	6	9	1	0
C:C:T117	C:C:T168	3.14	0	No	No	5	6	1	2
C:C:D171	C:C:T117	7.23	0	Yes	No	4	5	2	1
C:C:T117	Q:Q:P23	3.5	0	No	No	5	9	1	0
C:C:H203	C:C:L120	6.43	4	Yes	Yes	4	7	1	1
C:C:L120	C:C:W252	4.56	4	Yes	Yes	7	9	1	2
C:C:L120	Q:Q:P23	3.28	4	Yes	No	7	9	1	0
C:C:H203	C:C:Y121	5.44	4	Yes	Yes	4	7	1	2
C:C:D171	C:C:R188	11.91	0	Yes	Yes	4	5	2	2
C:C:F174	C:C:Y190	6.19	4	Yes	Yes	4	4	2	1
C:C:F174	C:C:W195	5.01	4	Yes	Yes	4	5	2	2
C:C:F189	C:C:S178	5.28	0	Yes	No	3	1	1	2
C:C:I185	Q:Q:S27	3.1	0	No	No	3	6	1	0
C:C:D187	C:C:R188	3.57	0	Yes	Yes	3	5	1	2
C:C:D187	C:C:F189	3.58	0	Yes	Yes	3	3	1	1
C:C:D187	Q:Q:S25	5.89	0	Yes	No	3	9	1	0
C:C:D187	Q:Q:S27	7.36	0	Yes	No	3	6	1	0
C:C:R188	C:C:Y190	15.43	0	Yes	Yes	5	4	2	1
C:C:F189	Q:Q:Y28	10.32	0	Yes	No	3	8	1	0
C:C:P191	C:C:Y190	4.17	0	No	Yes	5	4	2	1
C:C:W195	C:C:Y190	3.86	4	Yes	Yes	5	4	2	1
C:C:V196	C:C:Y190	6.31	0	No	Yes	4	4	2	1
C:C:F199	C:C:Y190	11.35	4	Yes	Yes	5	4	2	1
C:C:Y190	Q:Q:Y28	2.98	4	Yes	No	4	8	1	0
C:C:F199	C:C:W195	5.01	4	Yes	Yes	5	5	2	2
C:C:Q200	C:C:V196	2.87	0	Yes	No	5	4	1	2
C:C:D262	C:C:Q200	3.92	0	No	Yes	5	5	2	1
C:C:Q200	C:C:S263	4.33	0	Yes	No	5	5	1	2
C:C:Q200	Q:Q:V24	8.6	0	Yes	No	5	7	1	0
C:C:H203	C:C:Y255	5.44	4	Yes	Yes	4	7	1	1
C:C:H203	C:C:Y256	9.8	4	Yes	Yes	4	8	1	2
C:C:H203	Q:Q:P23	16.78	4	Yes	No	4	9	1	0
C:C:I204	C:C:I259	5.89	0	No	Yes	5	5	2	1
C:C:W252	C:C:Y255	6.75	4	Yes	Yes	9	7	2	1
C:C:W252	C:C:Y256	2.89	4	Yes	Yes	9	8	2	2
C:C:Y255	C:C:Y256	3.97	4	Yes	Yes	7	8	1	2
C:C:I259	C:C:Y255	9.67	4	Yes	Yes	5	7	1	1
C:C:E288	C:C:Y255	6.73	0	No	Yes	5	7	1	1
C:C:Y255	Q:Q:V24	7.57	4	Yes	No	7	7	1	0
C:C:I259	C:C:Y256	3.63	4	Yes	Yes	5	8	1	2
C:C:I259	C:C:I284	2.94	4	Yes	No	5	4	1	2
C:C:I259	Q:Q:V24	4.61	4	Yes	No	5	7	1	0
C:C:D262	C:C:H281	5.04	0	No	Yes	5	4	2	1
C:C:E268	C:C:K271	4.05	13	No	Yes	2	3	1	1
C:C:E268	Q:Q:R33	12.79	13	No	No	2	9	1	0
C:C:K271	Q:Q:R33	3.71	13	Yes	No	3	9	1	0
C:C:E277	C:C:H281	16	0	No	Yes	2	4	2	1
C:C:N278	Q:Q:R29	3.62	0	No	No	3	9	1	0
C:C:H281	Q:Q:L26	9	0	Yes	No	4	9	1	0
C:C:H281	Q:Q:R29	5.64	0	Yes	No	4	9	1	0
C:C:E288	C:C:F292	3.5	0	No	Yes	5	7	1	2
C:C:E288	Q:Q:K22	10.8	0	No	No	5	9	1	0
C:C:C28	C:C:R30	2.79	0	No	No	9	5	1	1
C:C:K25	Q:Q:E36	2.7	13	No	No	4	6	1	0
C:C:K25	Q:Q:F34	2.48	13	No	No	4	6	1	0
C:C:K271	Q:Q:F34	2.48	13	Yes	No	3	6	1	0
C:C:F189	C:C:N176	2.42	0	Yes	No	3	4	1	2
C:C:P27	Q:Q:P31	1.95	0	Yes	Yes	5	7	1	0
C:C:P27	Q:Q:V60	1.77	0	Yes	No	5	8	1	0

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
P:P:E26	P:P:P27	7.86	0	No	Yes	2	5	2	1
P:P:P27	U:U:C71	5.65	0	Yes	No	5	9	1	0
P:P:H281	P:P:R30	5.64	7	Yes	No	4	5	1	2
P:P:W94	P:P:Y45	2.89	8	Yes	Yes	7	7	1	2
P:P:F292	P:P:Y45	7.22	8	Yes	Yes	7	7	2	2
P:P:F87	P:P:Y116	8.25	8	Yes	No	7	6	2	1
P:P:F292	P:P:F87	15	8	Yes	Yes	7	7	2	2
P:P:D97	P:P:W94	3.35	0	No	Yes	5	7	2	1
P:P:V112	P:P:W94	7.36	0	Yes	Yes	5	7	2	1
P:P:H113	P:P:W94	7.41	8	Yes	Yes	6	7	1	1
P:P:W94	U:U:K22	12.76	8	Yes	Yes	7	9	1	0
P:P:C109	P:P:H113	2.95	8	Yes	Yes	9	6	2	1
P:P:C109	P:P:C186	7.28	8	Yes	No	9	9	2	2
P:P:D171	P:P:H113	6.3	0	Yes	Yes	4	6	2	1
P:P:A175	P:P:H113	4.39	0	No	Yes	4	6	2	1
P:P:C186	P:P:H113	4.42	8	No	Yes	9	6	2	1
P:P:H113	U:U:K22	5.24	8	Yes	Yes	6	9	1	0
P:P:F292	P:P:Y116	7.22	8	Yes	No	7	6	2	1
P:P:Y116	U:U:K22	7.17	8	No	Yes	6	9	1	0
P:P:T117	P:P:T168	3.14	0	No	Yes	5	6	1	2
P:P:D171	P:P:T117	7.23	0	Yes	No	4	5	2	1
P:P:T117	U:U:P23	3.5	0	No	Yes	5	9	1	0
P:P:H203	P:P:L120	6.43	3	Yes	No	4	7	1	1
P:P:L120	P:P:W252	4.56	3	No	Yes	7	9	1	2
P:P:L120	U:U:P23	3.28	3	No	Yes	7	9	1	0
P:P:H203	P:P:Y121	5.44	3	Yes	Yes	4	7	1	2
P:P:P170	P:P:R188	2.88	0	No	Yes	8	5	2	1
P:P:F199	P:P:P170	8.67	3	Yes	No	5	8	2	2
P:P:D171	P:P:R188	13.1	0	Yes	Yes	4	5	2	1
P:P:F174	P:P:Y190	6.19	3	Yes	Yes	4	4	2	1
P:P:F174	P:P:P191	2.89	3	Yes	No	4	5	2	2
P:P:F174	P:P:W195	6.01	3	Yes	Yes	4	5	2	2
P:P:I185	P:P:S178	3.1	0	No	No	3	1	1	2
P:P:F189	P:P:S178	5.28	3	Yes	No	3	1	1	2
P:P:I185	U:U:S27	3.1	0	No	No	3	6	1	0
P:P:D187	P:P:F189	3.58	3	Yes	Yes	3	3	1	1
P:P:D187	U:U:S25	5.89	3	Yes	No	3	9	1	0
P:P:D187	U:U:S27	7.36	3	Yes	No	3	6	1	0
P:P:D187	U:U:Y28	3.45	3	Yes	Yes	3	8	1	0
P:P:R188	P:P:Y190	9.26	0	Yes	Yes	5	4	1	1
P:P:R188	U:U:P23	4.32	0	Yes	Yes	5	9	1	0
P:P:F189	U:U:Y28	7.22	3	Yes	Yes	3	8	1	0
P:P:P191	P:P:Y190	4.17	3	No	Yes	5	4	2	1
P:P:W195	P:P:Y190	4.82	3	Yes	Yes	5	4	2	1
P:P:V196	P:P:Y190	6.31	0	No	Yes	4	4	2	1
P:P:F199	P:P:Y190	13.41	3	Yes	Yes	5	4	2	1
P:P:D193	P:P:V196	4.38	0	No	No	1	4	1	2
P:P:D193	U:U:C30	3.11	0	No	No	1	9	1	0
P:P:F199	P:P:W195	4.01	3	Yes	Yes	5	5	2	2
P:P:L266	P:P:V197	4.47	0	No	No	3	3	1	2
P:P:D262	P:P:Q200	5.22	0	No	No	5	5	2	1
P:P:Q200	P:P:S263	2.89	0	No	No	5	5	1	2
P:P:Q200	U:U:V24	4.3	0	No	No	5	7	1	0
P:P:H203	P:P:Y255	5.44	3	Yes	Yes	4	7	1	1
P:P:H203	P:P:Y256	10.89	3	Yes	Yes	4	8	1	2
P:P:H203	U:U:P23	15.25	3	Yes	Yes	4	9	1	0
P:P:I204	P:P:I259	5.89	0	No	Yes	5	5	2	1
P:P:W252	P:P:Y255	6.75	3	Yes	Yes	9	7	2	1
P:P:Y255	P:P:Y256	3.97	3	Yes	Yes	7	8	1	2
P:P:I259	P:P:Y255	10.88	3	Yes	Yes	5	7	1	1
P:P:T287	P:P:Y255	3.75	0	No	Yes	6	7	2	1
P:P:E288	P:P:Y255	5.61	0	No	Yes	5	7	1	1
P:P:Y255	U:U:V24	5.05	3	Yes	No	7	7	1	0
P:P:I259	P:P:Y256	3.63	3	Yes	Yes	5	8	1	2
P:P:I259	P:P:I284	5.89	3	Yes	No	5	4	1	2
P:P:I259	U:U:V24	3.07	3	Yes	No	5	7	1	0
P:P:D262	P:P:E277	3.9	0	No	Yes	5	2	2	1
P:P:E277	P:P:I265	4.1	7	Yes	Yes	2	3	1	2
P:P:L266	U:U:R29	4.86	0	No	Yes	3	9	1	0
P:P:E268	U:U:R33	8.14	0	No	No	2	9	1	0
P:P:E277	P:P:H281	18.46	7	Yes	Yes	2	4	1	1
P:P:E277	U:U:R29	4.65	7	Yes	Yes	2	9	1	0
P:P:H281	U:U:L26	6.43	7	Yes	No	4	9	1	0
P:P:H281	U:U:R29	3.39	7	Yes	Yes	4	9	1	0
P:P:S285	U:U:L26	4.5	0	No	No	5	9	1	0
P:P:E288	P:P:F292	3.5	0	No	Yes	5	7	1	2
P:P:E288	U:U:K22	9.45	0	No	Yes	5	9	1	0
P:P:K25	U:U:E36	2.7	0	No	No	4	6	1	0
P:P:E268	P:P:K271	2.7	0	No	No	2	3	1	2
P:P:K25	U:U:F34	2.48	0	No	No	4	6	1	0
P:P:F189	P:P:N176	2.42	3	Yes	No	3	4	1	2
P:P:Y190	U:U:Y28	1.99	3	Yes	Yes	4	8	1	0
P:P:P27	U:U:P31	1.95	0	Yes	Yes	5	7	1	0
P:P:C28	U:U:P31	1.88	0	No	Yes	9	7	1	0
P:P:P27	U:U:V60	1.77	0	Yes	No	5	8	1	0

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
S:S:E26	S:S:P27	7.86	0	No	No	2	5	2	1
S:S:C28	S:S:R30	4.18	0	No	No	9	5	1	1
M:M:R29	S:S:R30	3.2	0	Yes	No	9	5	0	1
S:S:W94	S:S:Y45	2.89	1	Yes	Yes	7	7	1	2
S:S:F292	S:S:Y45	8.25	1	Yes	Yes	7	7	2	2
S:S:F87	S:S:Y116	8.25	1	Yes	Yes	7	6	2	1
S:S:F292	S:S:F87	13.93	1	Yes	Yes	7	7	2	2
S:S:D97	S:S:W94	3.35	0	No	Yes	5	7	2	1
S:S:V112	S:S:W94	7.36	0	Yes	Yes	5	7	2	1
S:S:H113	S:S:W94	6.35	1	Yes	Yes	6	7	1	1
M:M:K22	S:S:W94	12.76	1	Yes	Yes	9	7	0	1
S:S:C109	S:S:H113	2.95	1	No	Yes	9	6	2	1
S:S:C109	S:S:C186	7.28	1	No	No	9	9	2	2
S:S:D171	S:S:H113	3.78	0	Yes	Yes	4	6	2	1
S:S:A175	S:S:H113	4.39	0	No	Yes	4	6	2	1
S:S:C186	S:S:H113	4.42	1	No	Yes	9	6	2	1
M:M:K22	S:S:H113	7.86	1	Yes	Yes	9	6	0	1
S:S:L120	S:S:Y116	3.52	1	Yes	Yes	7	6	1	1
S:S:F292	S:S:Y116	8.25	1	Yes	Yes	7	6	2	1
M:M:K22	S:S:Y116	4.78	1	Yes	Yes	9	6	0	1
S:S:T117	S:S:T168	3.14	0	No	No	5	6	1	2
S:S:D171	S:S:T117	11.56	0	Yes	No	4	5	2	1
M:M:P23	S:S:T117	3.5	1	No	No	9	5	0	1
S:S:H203	S:S:L120	5.14	1	Yes	Yes	4	7	1	1
S:S:L120	S:S:W252	5.69	1	Yes	Yes	7	9	1	2
M:M:P23	S:S:L120	3.28	1	No	Yes	9	7	0	1
S:S:H203	S:S:Y121	5.44	1	Yes	Yes	4	7	1	2
S:S:D171	S:S:R188	13.1	0	Yes	No	4	5	2	2
S:S:F174	S:S:Y190	6.19	1	Yes	Yes	4	4	2	1
S:S:F174	S:S:W195	5.01	1	Yes	Yes	4	5	2	2
S:S:F189	S:S:S178	3.96	0	Yes	No	3	1	1	2
S:S:D187	S:S:R188	4.76	0	Yes	No	3	5	1	2
S:S:D187	S:S:F189	3.58	0	Yes	Yes	3	3	1	1
M:M:S25	S:S:D187	5.89	0	No	Yes	9	3	0	1
M:M:S27	S:S:D187	8.83	0	No	Yes	6	3	0	1
S:S:R188	S:S:Y190	9.26	0	No	Yes	5	4	2	1
M:M:Y28	S:S:F189	9.28	0	Yes	Yes	8	3	0	1
S:S:P191	S:S:Y190	4.17	0	No	Yes	5	4	2	1
S:S:W195	S:S:Y190	4.82	1	Yes	Yes	5	4	2	1
S:S:V196	S:S:Y190	7.57	0	No	Yes	4	4	2	1
S:S:F199	S:S:Y190	12.38	1	Yes	Yes	5	4	2	1
M:M:Y28	S:S:Y190	2.98	0	Yes	Yes	8	4	0	1
S:S:F199	S:S:W195	4.01	1	Yes	Yes	5	5	2	2
S:S:L266	S:S:V197	4.47	0	No	No	3	3	1	2
S:S:D262	S:S:Q200	5.22	0	No	No	5	5	2	1
S:S:Q200	S:S:S263	5.78	0	No	No	5	5	1	2
M:M:V24	S:S:Q200	5.73	1	Yes	No	7	5	0	1
S:S:H203	S:S:Y255	6.53	1	Yes	Yes	4	7	1	1
S:S:H203	S:S:Y256	10.89	1	Yes	Yes	4	8	1	2
M:M:P23	S:S:H203	16.78	1	No	Yes	9	4	0	1
S:S:I204	S:S:I259	5.89	0	No	Yes	5	5	2	1
S:S:W252	S:S:Y255	5.79	1	Yes	Yes	9	7	2	1
S:S:Y255	S:S:Y256	4.96	1	Yes	Yes	7	8	1	2
S:S:I259	S:S:Y255	8.46	1	Yes	Yes	5	7	1	1
S:S:E288	S:S:Y255	5.61	0	No	Yes	5	7	1	1
M:M:V24	S:S:Y255	6.31	1	Yes	Yes	7	7	0	1
S:S:I259	S:S:Y256	3.63	1	Yes	Yes	5	8	1	2
S:S:I259	S:S:I284	5.89	1	Yes	No	5	4	1	2
M:M:V24	S:S:I259	6.14	1	Yes	Yes	7	5	0	1
S:S:D262	S:S:I284	4.2	0	No	No	5	4	2	2
S:S:E277	S:S:I265	4.1	0	No	Yes	2	3	1	2
M:M:R29	S:S:L266	3.64	0	Yes	No	9	3	0	1
S:S:E268	S:S:K271	9.45	0	No	No	2	3	1	2
M:M:R33	S:S:E268	10.47	0	No	No	9	2	0	1
M:M:R29	S:S:E277	8.14	0	Yes	No	9	2	0	1
M:M:L26	S:S:H281	7.71	0	No	No	9	4	0	1
S:S:E288	S:S:F292	3.5	0	No	Yes	5	7	1	2
M:M:K22	S:S:E288	10.8	1	Yes	No	9	5	0	1
S:S:H281	S:S:S285	2.79	0	No	No	4	5	1	2
M:M:E36	S:S:K25	2.7	0	No	No	6	4	0	1
M:M:F34	S:S:K25	2.48	0	No	No	6	4	0	1
S:S:F189	S:S:N176	2.42	0	Yes	No	3	4	1	2
S:S:N278	S:S:R30	2.41	0	No	No	3	5	2	1
M:M:C71	S:S:P27	1.88	0	No	No	9	5	0	1
M:M:P31	S:S:C28	1.88	0	No	No	7	9	0	1
M:M:R33	S:S:P27	1.44	0	No	No	9	5	0	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:R33	R:R:E26	8.14	21	No	No	9	2	0	1
L:L:F34	R:R:E26	3.5	21	No	No	6	2	0	1
R:R:F29	R:R:P27	8.67	0	No	No	4	5	1	1
R:R:C274	R:R:C28	7.28	0	No	No	5	9	2	1
L:L:P31	R:R:F29	4.33	0	No	No	7	4	0	1
R:R:F87	R:R:Y116	5.16	2	Yes	Yes	7	6	2	1
R:R:F292	R:R:F87	11.79	2	No	Yes	7	7	2	2
R:R:D97	R:R:W94	5.58	0	No	Yes	5	7	2	1
R:R:V112	R:R:W94	6.13	5	Yes	Yes	5	7	2	1
R:R:H113	R:R:W94	7.41	5	Yes	Yes	6	7	2	1
L:L:K22	R:R:W94	11.6	2	No	Yes	9	7	0	1
R:R:H113	R:R:R188	4.51	5	Yes	Yes	6	5	2	1
R:R:L120	R:R:Y116	3.52	2	Yes	Yes	7	6	1	1
R:R:E288	R:R:Y116	3.37	2	No	Yes	5	6	1	1
R:R:F292	R:R:Y116	7.22	2	No	Yes	7	6	2	1
L:L:K22	R:R:Y116	4.78	2	No	Yes	9	6	0	1
R:R:T117	R:R:Y121	3.75	0	Yes	Yes	5	7	1	2
R:R:T117	R:R:T168	3.14	0	Yes	No	5	6	1	2
R:R:D171	R:R:T117	14.45	0	No	Yes	4	5	2	1
L:L:P23	R:R:T117	3.5	2	No	Yes	9	5	0	1
R:R:H203	R:R:L120	5.14	2	Yes	Yes	4	7	1	1
R:R:L120	R:R:W252	4.56	2	Yes	Yes	7	9	1	2
L:L:P23	R:R:L120	3.28	2	No	Yes	9	7	0	1
R:R:H203	R:R:Y121	5.44	2	Yes	Yes	4	7	1	2
R:R:D171	R:R:R188	13.1	0	No	Yes	4	5	2	1
R:R:F189	R:R:S178	6.61	0	No	No	3	1	1	2
L:L:S27	R:R:I185	3.1	0	No	No	6	3	0	1
L:L:S25	R:R:D187	4.42	0	No	No	9	3	0	1
L:L:S27	R:R:D187	7.36	0	No	No	6	3	0	1
R:R:R188	R:R:Y190	9.26	0	Yes	Yes	5	4	1	2
L:L:S25	R:R:R188	3.95	0	No	Yes	9	5	0	1
L:L:Y28	R:R:F189	8.25	0	No	No	8	3	0	1
R:R:D262	R:R:Q200	3.92	0	Yes	No	5	5	1	1
R:R:Q200	R:R:S263	8.66	0	No	No	5	5	1	2
L:L:V24	R:R:Q200	5.73	2	Yes	No	7	5	0	1
R:R:H203	R:R:Y255	6.53	2	Yes	Yes	4	7	1	1
R:R:H203	R:R:Y256	10.89	2	Yes	Yes	4	8	1	2
L:L:P23	R:R:H203	18.3	2	No	Yes	9	4	0	1
R:R:I204	R:R:I259	5.89	0	No	Yes	5	5	2	1
R:R:W252	R:R:Y255	5.79	2	Yes	Yes	9	7	2	1
R:R:Y255	R:R:Y256	3.97	2	Yes	Yes	7	8	1	2
R:R:I259	R:R:Y255	8.46	2	Yes	Yes	5	7	1	1
R:R:E288	R:R:Y255	6.73	2	No	Yes	5	7	1	1
L:L:V24	R:R:Y255	5.05	2	Yes	Yes	7	7	0	1
R:R:I259	R:R:Y256	3.63	2	Yes	Yes	5	8	1	2
R:R:G258	R:R:I284	3.53	0	No	No	4	4	2	1
R:R:I259	R:R:I284	5.89	2	Yes	No	5	4	1	1
L:L:V24	R:R:I259	4.61	2	Yes	Yes	7	5	0	1
R:R:D262	R:R:V280	4.38	0	Yes	No	5	5	1	2
L:L:L26	R:R:D262	13.57	0	No	Yes	9	5	0	1
L:L:R29	R:R:D262	4.76	0	No	Yes	9	5	0	1
L:L:R29	R:R:L266	9.72	0	No	No	9	3	0	1
L:L:R29	R:R:E277	12.79	0	No	No	9	2	0	1
L:L:L26	R:R:I284	2.85	0	No	No	9	4	0	1
L:L:K22	R:R:E288	10.8	2	No	No	9	5	0	1
L:L:P31	R:R:C28	1.88	0	No	No	7	9	0	1
R:R:A180	R:R:I185	1.62	0	No	No	1	3	2	1
L:L:Q69	R:R:P27	1.58	0	No	No	9	5	0	1
R:R:E26	R:R:P27	1.57	21	No	No	2	5	1	1
L:L:R33	R:R:K271	1.24	21	No	No	9	3	0	1
L:L:N54	R:R:F189	1.21	0	No	No	8	3	0	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	9MEU_poly
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	2.85
Number of Linked Nodes	1367
Number of Links	1478
Number of Hubs	200
Number of Links mediated by Hubs	682
Number of Communities	37
Number of Nodes involved in Communities	239
Number of Links involved in Communities	311

Path Summary
Number Of Nodes in MetaPath	74
Number Of Links MetaPath	73
Number of Shortest Paths	2187479
Length Of Smallest Path	3
Average Path Length	33.2787
Length of Longest Path	66
Minimum Path Strength	1.22
Average Path Strength	5.75187
Maximum Path Strength	18.25
Minimum Path Correlation	0.7
Average Path Correlation	0.995358
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	3.7037
Average % Of Corr. Nodes	52.8123
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	46.098
Maximum Path Hubs %	100

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P61073
Sequence	>9MEU_poly_Chain_R E P C F R E E N A N F N K I F L P T I Y S I I F L T G I V G N G L V I L V M G Y Q K K L R S M T D K Y R L H L S V A D L L F V I T L P F W A V D A V A N W Y F G N F L C K A V H V I Y T V N L Y S S V L I L A F I S L D R Y L A I V H A T N S Q R P R K L L A E K V V Y V G V W I P A L L L T I P D F I F A N V S E A D D R Y I C D R F Y P N D L W V V V F Q F Q H I M V G L I L P G I V I L S C Y C I I I S K L S H S K G H Q K R K A L K T T V I L I L A F F A C W L P Y Y I G I S I D S F I L L E I I K Q G C E F E N T V H K W I S I T E A L A F F H C C L N P I L Y A F L G Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	3ODU	A	Protein	Chemokine	CXCR4	Homo sapiens	IT1t	-	-	2.5	2010-10-27	doi.org/10.1126/science.1194396
	3OE0	A	Protein	Chemokine	CXCR4	Homo sapiens	CVX15	-	-	2.9	2010-10-27	doi.org/10.1126/science.1194396
	3OE6	A	Protein	Chemokine	CXCR4	Homo sapiens	IT1t	-	-	3.2	2010-10-27	doi.org/10.1126/science.1194396
	3OE8	A	Protein	Chemokine	CXCR4	Homo sapiens	IT1t	-	-	3.1	2010-10-27	doi.org/10.1126/science.1194396
	3OE9	A	Protein	Chemokine	CXCR4	Homo sapiens	IT1t	-	-	3.1	2010-10-27	doi.org/10.1126/science.1194396
	4RWS	A	Protein	Chemokine	CXCR4	Homo sapiens	vMIP-II	-	-	3.1	2015-02-11	doi.org/10.1126/science.1261064
	8K3Z	A	Protein	Chemokine	CXCR4	Homo sapiens	CXCL12	-	Gi1/β1/γ1	2.81	2024-07-17	doi.org/10.1016/j.celrep.2024.114578
	8K3Z (No Gprot)	A	Protein	Chemokine	CXCR4	Homo sapiens	CXCL12	-		2.81	2024-07-17	doi.org/10.1016/j.celrep.2024.114578
	8ZPL	A	Protein	Chemokine	CXCR4	Homo sapiens	HF51116	-	-	3.01	2025-02-26	doi.org/10.1073/pnas.2425795122
	8ZPM	A	Protein	Chemokine	CXCR4	Homo sapiens	AMD070	-	-	3.2	2025-02-26	doi.org/10.1073/pnas.2425795122
	8ZPN	A	Protein	Chemokine	CXCR4	Homo sapiens	AMD3100	-	-	3.31	2025-02-26	doi.org/10.1073/pnas.2425795122
	8YU7	A	Protein	Chemokine	CXCR4	Homo sapiens	-	-	-	3.01	2025-03-05	doi.org/10.1016/j.celrep.2025.115255
	9MDU	A	Protein	Chemokine	CXCR4	Homo sapiens	-	-	-	2.9	2025-09-10	To be published
	9ME1	A	Protein	Chemokine	CXCR4	Homo sapiens	CXCL12	-	-	3.37	2025-09-10	To be published
	9MEJ	A	Protein	Chemokine	CXCR4	Homo sapiens	Gp120	-	-	3.99	2025-09-10	To be published
	9MEN	A	Protein	Chemokine	CXCR4	Homo sapiens	Gp120 (V3 loop)	-	-	3.57	2025-09-10	To be published
	9MET	A	Protein	Chemokine	CXCR4	Homo sapiens	Gp120; CD4	-	-	5.65	2025-09-10	To be published
	9MEU	A	Protein	Chemokine	CXCR4	Homo sapiens	CXCL12	-	-	3.46	2025-09-10	To be published
	8U4N	A	Protein	Chemokine	CXCR4	Homo sapiens	-	-	Gi1/β1/γ2	2.72	2024-03-13	doi.org/10.1101/2024.02.09.579708
	8U4N (No Gprot)	A	Protein	Chemokine	CXCR4	Homo sapiens	-	-		2.72	2024-03-13	doi.org/10.1101/2024.02.09.579708
	8U4O	A	Protein	Chemokine	CXCR4	Homo sapiens	CXCL12	-	Gi1/β1/γ2	3.29	2024-03-13	doi.org/10.1101/2024.02.09.579708
	8U4O (No Gprot)	A	Protein	Chemokine	CXCR4	Homo sapiens	CXCL12	-		3.29	2024-03-13	doi.org/10.1101/2024.02.09.579708
	8U4P	A	Protein	Chemokine	CXCR4	Homo sapiens	AMD3100	-	Gi1/β1/γ2	3.15	2024-03-13	doi.org/10.1101/2024.02.09.579708
	8U4P (No Gprot)	A	Protein	Chemokine	CXCR4	Homo sapiens	AMD3100	-		3.15	2024-03-13	doi.org/10.1101/2024.02.09.579708
	8U4Q	A	Protein	Chemokine	CXCR4	Homo sapiens	REGN7663-Fab	-	Gi1/β1/γ2	3.36	2024-03-13	doi.org/10.1101/2024.02.09.579708
	8U4Q (No Gprot)	A	Protein	Chemokine	CXCR4	Homo sapiens	REGN7663-Fab	-		3.36	2024-03-13	doi.org/10.1101/2024.02.09.579708
	8U4R	A	Protein	Chemokine	CXCR4	Homo sapiens	REGN7663-Fab	-	-	3.1	2024-03-13	doi.org/10.1101/2024.02.09.579708
	8U4S	A	Protein	Chemokine	CXCR4	Homo sapiens	REGN7663-Fab	-	-	3.35	2024-03-13	doi.org/10.1038/s41594-024-01397-1
	8U4T	A	Protein	Chemokine	CXCR4	Homo sapiens	REGN7663-Fab	-	-	3.38	2024-03-13	doi.org/10.1038/s41594-024-01397-1

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 9MEU_poly.zip

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