psnGPCR

Press and hold down the left mouse button and move the mouse to rotate.
Press and hold down the central mouse button and move the mouse to translate.
Use the mouse wheel to zoom in or out.
Click on any atom on your molecule and the corresponding residue label will be placed beneath the viewer.

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:N924	R:R:T923	4.39	Yes	No	1	8	9
2	R:R:D946	R:R:T923	8.67	No	No	1	4	9
3	R:R:A926	R:R:N924	3.13	No	Yes	0	9	8
4	R:R:D946	R:R:N924	2.69	No	Yes	1	4	8
5	R:R:N924	R:R:T949	2.92	Yes	Yes	1	8	8
6	R:R:F925	R:R:L928	3.65	Yes	Yes	0	9	9
7	R:R:F925	R:R:T949	6.49	Yes	Yes	1	9	8
8	R:R:F925	R:R:I953	5.02	Yes	Yes	1	9	9
9	R:R:F925	R:R:S1181	3.96	Yes	No	0	9	7
10	R:R:A926	R:R:F1176	2.77	No	Yes	0	9	9
11	R:R:F1019	R:R:L928	6.09	No	Yes	0	9	9
12	R:R:L928	R:R:W1081	5.69	Yes	No	0	9	6
13	R:R:L928	R:R:W1158	2.28	Yes	Yes	0	9	8
14	R:R:F1092	R:R:M929	3.73	No	Yes	0	9	9
15	R:R:I1093	R:R:M929	5.83	Yes	Yes	0	8	9
16	R:R:M929	R:R:W1158	4.65	Yes	Yes	3	9	8
17	R:R:L1162	R:R:M929	2.83	No	Yes	0	8	9
18	R:R:F1176	R:R:M929	2.49	Yes	Yes	3	9	9
19	R:R:H931	R:R:V932	5.54	No	No	0	6	5
20	R:R:E933	R:R:V934	4.28	No	No	0	4	4
21	R:R:E933	R:R:L1084	2.65	No	No	0	4	5
22	R:R:H936	R:R:V934	2.77	No	No	0	1	4
23	R:R:K935	R:R:Y1164	7.17	No	No	0	2	6
24	R:R:D942	R:R:S937	5.89	No	No	0	4	1
25	R:R:A939	R:R:H941	4.39	No	No	0	1	5
26	R:R:H941	R:R:V1170	5.54	No	No	7	5	4
27	R:R:H941	R:R:Y1174	6.53	No	Yes	7	5	9
28	R:R:L944	R:R:Y1174	2.34	No	Yes	0	5	9
29	R:R:L945	R:R:Y1174	5.86	No	Yes	0	8	9
30	R:R:I948	R:R:Y1174	2.42	No	Yes	0	9	9
31	R:R:I953	R:R:T949	3.04	Yes	Yes	1	9	8
32	R:R:T1177	R:R:T949	4.71	No	Yes	0	9	8
33	R:R:L996	R:R:W950	6.83	No	No	0	9	7
34	R:R:G952	R:R:S1181	3.71	No	No	0	9	7
35	R:R:G952	R:R:L1182	3.42	No	No	0	9	6
36	R:R:E992	R:R:I953	5.47	No	Yes	1	9	9
37	R:R:F995	R:R:I953	2.51	No	Yes	0	8	9
38	R:R:I953	R:R:L996	5.71	Yes	No	0	9	9
39	R:R:L955	R:R:M1185	2.83	No	Yes	0	6	7
40	R:R:L957	R:R:S956	3	No	Yes	1	9	9
41	R:R:L960	R:R:S956	3	Yes	Yes	1	9	9
42	R:R:E992	R:R:S956	4.31	No	Yes	1	9	9
43	R:R:G1184	R:R:S956	3.71	No	Yes	1	8	9
44	R:R:E992	R:R:L957	3.98	No	No	1	9	9
45	R:R:L957	R:R:L993	2.77	No	No	0	9	5
46	R:R:C959	R:R:M1185	3.24	No	Yes	0	9	7
47	R:R:C959	R:R:F1188	11.17	No	Yes	0	9	7
48	R:R:C985	R:R:L960	3.17	No	Yes	0	9	9
49	R:R:F989	R:R:L960	4.87	No	Yes	0	8	9
50	R:R:G1184	R:R:L960	3.42	No	Yes	1	8	9
51	R:R:F989	R:R:L961	7.31	No	No	0	8	5
52	R:R:F1188	R:R:I962	8.79	Yes	No	0	7	5
53	R:R:C963	R:R:C985	3.64	No	No	0	7	9
54	R:R:C963	R:R:F1188	4.19	No	Yes	8	7	7
55	R:R:C1192	R:R:C963	3.64	No	No	8	9	7
56	R:R:C985	R:R:I964	3.27	No	No	0	9	7
57	R:R:I964	R:R:I986	4.42	No	No	0	7	5
58	R:R:F965	R:R:F969	7.5	No	No	0	8	8
59	R:R:F967	R:R:T966	3.89	No	No	0	9	9
60	R:R:T966	R:R:Y1202	11.24	No	Yes	0	9	7
61	R:R:F967	R:R:N978	8.46	No	Yes	0	9	9
62	R:R:F967	R:R:H981	6.79	No	Yes	0	9	9
63	R:R:C968	R:R:F969	4.19	No	No	0	8	8
64	R:R:C968	R:R:K982	3.23	No	No	0	8	9
65	R:R:F970	R:R:L973	2.44	Yes	Yes	9	8	8
66	R:R:E1201	R:R:F970	10.49	No	Yes	9	8	8
67	R:R:F970	R:R:Y1202	4.13	Yes	Yes	0	8	7
68	R:R:C1205	R:R:F970	6.98	No	Yes	0	8	8
69	R:R:L973	R:R:N978	4.12	Yes	Yes	0	8	9
70	R:R:L973	R:R:V1198	2.98	Yes	No	0	8	9
71	R:R:E1201	R:R:L973	2.65	No	Yes	9	8	8
72	R:R:N978	R:R:Q974	3.96	Yes	No	0	9	9
73	R:R:D976	R:R:R1048	5.96	No	Yes	0	9	4
74	R:R:D976	R:R:F1051	3.58	No	No	0	9	5
75	R:R:H981	R:R:R977	5.64	Yes	No	5	9	9
76	R:R:E1029	R:R:R977	8.14	Yes	No	5	9	9
77	R:R:Q1032	R:R:R977	2.34	Yes	No	0	8	9
78	R:R:R1048	R:R:T979	6.47	Yes	No	2	4	9
79	R:R:T979	R:R:Y1052	3.75	No	No	2	9	9
80	R:R:I980	R:R:W1025	7.05	No	Yes	0	9	9
81	R:R:E1029	R:R:I980	8.2	Yes	No	0	9	9
82	R:R:E1029	R:R:H981	9.85	Yes	Yes	5	9	9
83	R:R:H981	R:R:L1153	3.86	Yes	Yes	5	9	9
84	R:R:N983	R:R:W1025	18.08	No	Yes	2	9	9
85	R:R:N983	R:R:Y1052	9.3	No	No	2	9	9
86	R:R:N983	R:R:Y1056	3.49	No	Yes	2	9	9
87	R:R:L984	R:R:W1025	2.28	No	Yes	0	9	9
88	R:R:L984	R:R:M1026	4.24	No	Yes	0	9	8
89	R:R:A1021	R:R:S987	3.42	No	No	2	8	8
90	R:R:S987	R:R:Y1056	2.54	No	Yes	2	8	9
91	R:R:F1018	R:R:V990	11.8	No	No	0	8	5
92	R:R:A991	R:R:F1019	8.32	No	No	0	8	9
93	R:R:L1015	R:R:L994	4.15	No	No	0	9	5
94	R:R:F995	R:R:I999	2.51	No	No	0	8	8
95	R:R:G998	R:R:I997	3.53	No	No	0	9	5
96	R:R:F1011	R:R:G998	3.01	No	No	0	5	9
97	R:R:I999	R:R:N1000	11.33	No	No	0	8	6
98	R:R:N1000	R:R:V1079	2.96	No	No	0	6	5
99	R:R:Q1004	R:R:R1001	2.34	Yes	No	0	4	8
100	R:R:C1080	R:R:T1002	3.38	No	No	0	8	7
101	R:R:D1003	R:R:Q1004	11.75	No	Yes	0	4	4
102	R:R:A1007	R:R:Q1004	6.06	No	Yes	0	4	4
103	R:R:C1008	R:R:C1080	7.28	No	No	0	9	8
104	R:R:A1012	R:R:Y1074	4	No	Yes	0	9	9
105	R:R:A1013	R:R:Y1074	2.67	No	Yes	0	8	9
106	R:R:L1015	R:R:W1081	3.42	No	No	0	9	6
107	R:R:H1016	R:R:L1020	6.43	No	No	0	9	9
108	R:R:H1016	R:R:S1091	4.18	No	Yes	0	9	9
109	R:R:F1092	R:R:H1016	3.39	No	No	0	9	9
110	R:R:F1017	R:R:F1018	3.22	Yes	No	0	8	8
111	R:R:F1017	R:R:P1059	4.33	Yes	Yes	0	8	9
112	R:R:F1017	R:R:V1063	2.62	Yes	No	0	8	9
113	R:R:L1020	R:R:P1059	3.28	No	Yes	0	9	9
114	R:R:I1062	R:R:L1020	2.85	No	No	0	8	9
115	R:R:A1021	R:R:Y1056	2.67	No	Yes	2	8	9
116	R:R:F1023	R:R:M1026	2.49	No	Yes	0	9	8
117	R:R:A1096	R:R:F1023	2.77	No	No	0	8	9
118	R:R:F1023	R:R:W1158	15.03	No	Yes	0	9	8
119	R:R:P1059	R:R:T1024	3.5	Yes	No	0	9	5
120	R:R:L1028	R:R:W1025	5.69	No	Yes	0	7	9
121	R:R:G1055	R:R:W1025	4.22	No	Yes	0	8	9
122	R:R:W1025	R:R:Y1056	5.79	Yes	Yes	2	9	9
123	R:R:M1026	R:R:Q1183	4.08	Yes	No	0	8	9
124	R:R:F1027	R:R:V1031	2.62	No	No	0	9	9
125	R:R:F1027	R:R:I1099	8.79	No	No	0	9	5
126	R:R:F1027	R:R:L1102	7.31	No	No	0	9	4
127	R:R:F1051	R:R:L1028	3.65	No	No	0	5	7
128	R:R:E1029	R:R:L1153	3.98	Yes	Yes	5	9	9
129	R:R:I1035	R:R:Q1032	8.23	No	Yes	0	7	8
130	R:R:M1036	R:R:Q1032	2.72	No	Yes	0	8	8
131	R:R:F1051	R:R:Q1032	2.34	No	Yes	0	5	8
132	R:R:A1110	R:R:L1033	3.15	No	No	0	8	9
133	R:R:I1035	R:R:Y1034	3.63	No	Yes	0	7	8
134	R:R:V1038	R:R:Y1034	12.62	No	Yes	0	8	8
135	R:R:E1039	R:R:Y1034	12.35	No	Yes	0	8	8
136	R:R:F1106	R:R:Y1034	3.09	No	Yes	0	6	8
137	R:R:R1047	R:R:S1043	7.91	No	No	0	9	9
138	R:R:E1044	R:R:H1045	2.46	No	No	0	7	4
139	R:R:R1048	R:R:Y1052	3.09	Yes	No	2	4	9
140	R:R:K1049	R:R:Y1050	9.55	No	No	0	8	9
141	R:R:L1061	R:R:V1065	2.98	No	No	0	5	8
142	R:R:S1066	R:R:Y1074	2.54	No	Yes	4	9	9
143	R:R:F1088	R:R:S1066	7.93	Yes	No	4	8	9
144	R:R:S1066	R:R:S1091	3.26	No	Yes	4	9	9
145	R:R:A1067	R:R:Y1074	4	No	Yes	0	8	9
146	R:R:D1070	R:R:S1073	10.31	No	No	0	9	9
147	R:R:R1072	R:R:Y1071	18.52	No	No	0	4	8
148	R:R:R1083	R:R:S1073	2.64	No	No	0	5	9
149	R:R:F1088	R:R:S1073	5.28	Yes	No	0	8	9
150	R:R:F1088	R:R:Y1074	6.19	Yes	Yes	4	8	9
151	R:R:R1083	R:R:T1076	9.06	No	No	0	5	9
152	R:R:L1082	R:R:W1081	6.83	Yes	No	0	8	6
153	R:R:F1088	R:R:L1082	6.09	Yes	Yes	4	8	8
154	R:R:I1089	R:R:L1082	4.28	No	Yes	0	9	8
155	R:R:L1082	R:R:S1091	4.5	Yes	Yes	4	8	9
156	R:R:D1085	R:R:R1083	15.48	No	No	0	8	5
157	R:R:D1085	R:R:T1086	2.89	No	No	0	8	8
158	R:R:W1090	R:R:Y1087	2.89	No	No	0	7	6
159	R:R:F1088	R:R:S1091	6.61	Yes	Yes	4	8	9
160	R:R:I1089	R:R:I1093	4.42	No	Yes	0	9	8
161	R:R:I1093	R:R:W1090	5.87	Yes	No	0	8	7
162	R:R:G1094	R:R:P1095	4.06	No	No	0	9	9
163	R:R:L1098	R:R:M1101	2.83	No	No	0	5	4
164	R:R:I1100	R:R:L1156	2.85	No	Yes	0	9	6
165	R:R:L1154	R:R:N1103	16.48	Yes	No	0	6	9
166	R:R:L1156	R:R:V1104	4.47	Yes	No	0	6	6
167	R:R:L1107	R:R:L1150	2.77	Yes	No	0	8	9
168	R:R:L1107	R:R:L1154	2.77	Yes	Yes	6	8	6
169	R:R:G1108	R:R:L1111	3.42	No	No	0	5	5
170	R:R:H1117	R:R:K1113	3.93	No	No	0	6	7
171	R:R:F1115	R:R:W1143	16.04	No	No	0	4	7
172	R:R:H1116	R:R:H1117	7.17	No	No	0	5	6
173	R:R:I1148	R:R:V1144	3.07	No	No	0	5	8
174	R:R:F1190	R:R:I1148	5.02	Yes	No	0	8	5
175	R:R:A1149	R:R:F1190	5.55	No	Yes	0	5	8
176	R:R:L1151	R:R:L1156	2.77	No	Yes	6	9	6
177	R:R:C1152	R:R:F1186	8.38	No	No	0	6	8
178	R:R:I1187	R:R:L1153	4.28	No	Yes	0	9	9
179	R:R:H1191	R:R:L1153	10.29	No	Yes	0	8	9
180	R:R:F1160	R:R:T1157	2.59	Yes	No	3	8	9
181	R:R:F1179	R:R:T1157	3.89	No	No	3	8	9
182	R:R:N1180	R:R:T1157	8.77	No	No	3	9	9
183	R:R:F1176	R:R:W1158	5.01	Yes	Yes	3	9	8
184	R:R:N1180	R:R:W1158	16.95	No	Yes	3	9	8
185	R:R:Q1183	R:R:W1158	5.48	No	Yes	0	9	8
186	R:R:F1160	R:R:M1172	4.98	Yes	No	0	8	8
187	R:R:F1160	R:R:L1175	9.74	Yes	No	0	8	9
188	R:R:F1160	R:R:F1176	3.22	Yes	Yes	3	8	9
189	R:R:F1160	R:R:F1179	5.36	Yes	No	3	8	8
190	R:R:F1176	R:R:G1161	7.53	Yes	No	0	9	9
191	R:R:M1163	R:R:M1172	4.33	No	No	0	6	8
192	R:R:T1169	R:R:Y1164	2.5	No	No	0	8	6
193	R:R:A1173	R:R:Y1164	9.34	No	No	0	9	6
194	R:R:I1165	R:R:N1166	2.83	No	No	0	6	7
195	R:R:N1166	R:R:T1169	5.85	No	No	0	7	8
196	R:R:V1170	R:R:Y1174	5.05	No	Yes	7	4	9
197	R:R:F1176	R:R:N1180	16.92	Yes	No	3	9	9
198	R:R:F1179	R:R:I1178	7.54	No	No	0	8	5
199	R:R:L1182	R:R:M1185	2.83	No	Yes	0	6	7
200	R:R:I1189	R:R:M1185	2.92	No	Yes	0	7	7
201	R:R:F1188	R:R:I1189	3.77	Yes	No	0	7	7
202	R:R:C1192	R:R:F1188	5.59	No	Yes	8	9	7
203	R:R:F1188	R:R:V1193	2.62	Yes	No	0	7	5
204	R:R:F1190	R:R:I1189	3.77	Yes	No	0	8	7
205	R:R:F1190	R:R:L1194	6.09	Yes	No	0	8	9
206	R:R:Q1195	R:R:V1198	2.87	No	No	0	8	9
207	R:R:V1198	R:R:Y1202	6.31	No	Yes	0	9	7
208	R:R:G1203	R:R:R1207	4.5	No	No	0	5	8
209	R:R:H1116	R:R:Y1112	2.18	No	No	0	5	4
210	R:R:G1057	R:R:P1059	2.03	No	Yes	0	6	9
211	R:R:A1012	R:R:G1075	1.95	No	No	0	9	9
212	R:R:A1149	R:R:G1146	1.95	No	No	0	5	8
213	R:R:G1146	R:R:I1145	1.76	No	No	0	8	6
214	R:R:G1155	R:R:M1026	1.75	No	Yes	0	6	8
215	R:R:G1030	R:R:L1033	1.71	No	No	0	5	9
216	R:R:G1030	R:R:L1154	1.71	No	Yes	0	5	6
217	R:R:G1108	R:R:L1107	1.71	No	Yes	0	5	8
218	R:R:M1058	R:R:P1059	1.68	No	Yes	0	4	9
219	R:R:C968	R:R:I964	1.64	No	No	0	8	7
220	R:R:E1029	R:R:G1030	1.64	Yes	No	0	9	5
221	R:R:C1152	R:R:I1148	1.64	No	No	0	6	5
222	R:R:A1110	R:R:M1114	1.61	No	No	0	8	8
223	R:R:V932	R:R:V934	1.6	No	No	0	5	4
224	R:R:V947	R:R:V951	1.6	No	No	0	6	8
225	R:R:V1065	R:R:V1069	1.6	No	No	0	8	7
226	R:R:T1024	R:R:V1054	1.59	No	No	0	5	4
227	R:R:A1022	R:R:L988	1.58	No	No	0	8	9
228	R:R:P1005	R:R:Q1004	1.58	No	Yes	0	3	4
229	R:R:A1147	R:R:L1111	1.58	No	No	0	9	5
230	R:R:I1165	R:R:V932	1.54	No	No	0	6	5
231	R:R:A939	R:R:D938	1.54	No	No	0	1	1
232	R:R:I1109	R:R:V1038	1.54	No	No	0	6	8
233	R:R:I948	R:R:T1177	1.52	No	No	0	9	9
234	R:R:I1093	R:R:T1097	1.52	Yes	No	0	8	6
235	R:R:M1101	R:R:T1097	1.51	No	No	0	4	6
236	R:R:G998	R:R:R1001	1.5	No	No	0	9	8
237	R:R:K1078	R:R:T1076	1.5	No	No	0	4	9
238	R:R:L943	R:R:V947	1.49	No	No	0	4	6
239	R:R:N978	R:R:S975	1.49	Yes	No	0	9	7
240	R:R:L1014	R:R:V1010	1.49	No	No	0	5	6
241	R:R:L1053	R:R:V1054	1.49	No	No	0	4	4
242	R:R:N924	R:R:V927	1.48	Yes	No	0	8	7
243	R:R:D1077	R:R:T1076	1.45	No	No	0	1	9
244	R:R:I1109	R:R:K1113	1.45	No	No	0	6	7
245	R:R:G1203	R:R:Y1202	1.45	No	Yes	0	5	7
246	R:R:E1167	R:R:S1168	1.44	No	No	0	5	6
247	R:R:I1187	R:R:L988	1.43	No	No	0	9	9
248	R:R:I997	R:R:L993	1.43	No	No	0	5	5
249	R:R:I1105	R:R:L1102	1.43	No	No	0	5	4
250	R:R:I1171	R:R:L1175	1.43	No	No	0	6	9
251	R:R:I1099	R:R:N1103	1.42	No	No	0	5	9
252	R:R:K1197	R:R:L973	1.41	No	Yes	0	9	8
253	R:R:K1113	R:R:L1037	1.41	No	No	0	7	8
254	R:R:L1061	R:R:M1058	1.41	No	No	0	5	4
255	R:R:G1094	R:R:W1090	1.41	No	No	0	9	7
256	R:R:A1060	R:R:F1017	1.39	No	Yes	0	7	8
257	R:R:D942	R:R:K935	1.38	No	No	0	4	2
258	R:R:L954	R:R:L996	1.38	No	No	0	6	9
259	R:R:L1014	R:R:L994	1.38	No	No	0	5	5
260	R:R:L1107	R:R:L1151	1.38	Yes	No	6	8	9
261	R:R:L1107	R:R:L1156	1.38	Yes	Yes	6	8	6
262	R:R:L1154	R:R:L1156	1.38	Yes	Yes	6	6	6
263	R:R:E1201	R:R:K1204	1.35	No	No	0	8	7
264	R:R:H931	R:R:I1093	1.33	No	Yes	0	6	8
265	R:R:R1048	R:R:S1046	1.32	Yes	No	0	4	9
266	R:R:E1167	R:R:N1166	1.31	No	No	0	5	7
267	R:R:R1199	R:R:V1193	1.31	No	No	0	7	5
268	R:R:D1070	R:R:R1072	1.19	No	No	0	9	4
269	R:R:L1206	R:R:Y1202	1.17	No	Yes	0	5	7
270	R:R:M1114	R:R:W1143	1.16	No	No	0	8	7
271	R:R:R1047	R:R:Y1050	1.03	No	No	0	9	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:N924	2.922	5	1	8
2	R:R:F925	4.78	4	1	9
3	R:R:L928	4.4275	4	0	9
4	R:R:M929	3.906	5	3	9
5	R:R:T949	4.29	4	1	8
6	R:R:I953	4.35	5	1	9
7	R:R:S956	3.505	4	1	9
8	R:R:L960	3.615	4	1	9
9	R:R:F970	6.01	4	9	8
10	R:R:L973	2.72	5	9	8
11	R:R:N978	4.5075	4	0	9
12	R:R:H981	6.535	4	5	9
13	R:R:Q1004	5.4325	4	0	4
14	R:R:F1017	2.89	4	0	8
15	R:R:W1025	7.185	6	2	9
16	R:R:M1026	3.14	4	0	8
17	R:R:E1029	6.362	5	5	9
18	R:R:Q1032	3.9075	4	0	8
19	R:R:Y1034	7.9225	4	0	8
20	R:R:R1048	4.21	4	2	4
21	R:R:Y1056	3.6225	4	2	9
22	R:R:P1059	2.964	5	0	9
23	R:R:Y1074	3.88	5	4	9
24	R:R:L1082	5.425	4	4	8
25	R:R:F1088	6.42	5	4	8
26	R:R:S1091	4.6375	4	4	9
27	R:R:I1093	3.794	5	0	8
28	R:R:L1107	2.002	5	6	8
29	R:R:L1153	5.6025	4	5	9
30	R:R:L1154	5.585	4	6	6
31	R:R:L1156	2.57	5	6	6
32	R:R:W1158	8.23333	6	3	8
33	R:R:F1160	5.178	5	3	8
34	R:R:Y1174	4.44	5	7	9
35	R:R:F1176	6.32333	6	3	9
36	R:R:M1185	2.955	4	0	7
37	R:R:F1188	6.02167	6	8	7
38	R:R:F1190	5.1075	4	0	8
39	R:R:Y1202	4.86	5	0	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:F925	R:R:T949	11.6713	6.49	Yes	Yes	1	9	8
2	R:R:F925	R:R:L928	71.8201	3.65	Yes	Yes	0	9	9
3	R:R:F925	R:R:S1181	28.7889	3.96	Yes	No	0	9	7
4	R:R:L928	R:R:W1081	28.9547	5.69	Yes	No	0	9	6
5	R:R:F1176	R:R:W1158	11.9604	5.01	Yes	Yes	3	9	8
6	R:R:I1093	R:R:M929	27.9448	5.83	Yes	Yes	0	8	9
7	R:R:H931	R:R:I1093	19.5537	1.33	No	Yes	0	6	8
8	R:R:H931	R:R:V932	18.3742	5.54	No	No	0	6	5
9	R:R:I1165	R:R:N1166	11.2627	2.83	No	No	0	6	7
10	R:R:I1165	R:R:V932	12.5	1.54	No	No	0	6	5
11	R:R:I948	R:R:Y1174	10.1719	2.42	No	Yes	0	9	9
12	R:R:I948	R:R:T1177	11.6289	1.52	No	No	0	9	9
13	R:R:T1177	R:R:T949	13.0782	4.71	No	Yes	0	9	8
14	R:R:G952	R:R:S1181	27.7212	3.71	No	No	0	9	7
15	R:R:G952	R:R:L1182	26.6728	3.42	No	No	0	9	6
16	R:R:E992	R:R:I953	29.7217	5.47	No	Yes	1	9	9
17	R:R:L1182	R:R:M1185	25.6591	2.83	No	Yes	0	6	7
18	R:R:E992	R:R:L957	11.945	3.98	No	No	1	9	9
19	R:R:E992	R:R:S956	16.7322	4.31	No	Yes	1	9	9
20	R:R:L960	R:R:S956	15.6722	3	Yes	Yes	1	9	9
21	R:R:L957	R:R:L993	11.9295	2.77	No	No	0	9	5
22	R:R:I1189	R:R:M1185	17.0405	2.92	No	Yes	0	7	7
23	R:R:C985	R:R:L960	12.4576	3.17	No	Yes	0	9	9
24	R:R:F1023	R:R:W1158	51.7268	15.03	No	Yes	0	9	8
25	R:R:F1023	R:R:M1026	51.0947	2.49	No	Yes	0	9	8
26	R:R:L984	R:R:M1026	100	4.24	No	Yes	0	9	8
27	R:R:L984	R:R:W1025	99.021	2.28	No	Yes	0	9	9
28	R:R:I980	R:R:W1025	68.4243	7.05	No	Yes	0	9	9
29	R:R:E1029	R:R:I980	67.3373	8.2	Yes	No	0	9	9
30	R:R:E1029	R:R:H981	30.0493	9.85	Yes	Yes	5	9	9
31	R:R:F967	R:R:H981	30.5928	6.79	No	Yes	0	9	9
32	R:R:F967	R:R:T966	13.3865	3.89	No	No	0	9	9
33	R:R:Q1183	R:R:W1158	51.1679	5.48	No	Yes	0	9	8
34	R:R:M1026	R:R:Q1183	50.8518	4.08	Yes	No	0	8	9
35	R:R:F967	R:R:N978	16.0692	8.46	No	Yes	0	9	9
36	R:R:L973	R:R:N978	11.6058	4.12	Yes	Yes	0	8	9
37	R:R:T966	R:R:Y1202	11.8871	11.24	No	Yes	0	9	7
38	R:R:L1020	R:R:P1059	21.743	3.28	No	Yes	0	9	9
39	R:R:H1016	R:R:L1020	24.7263	6.43	No	No	0	9	9
40	R:R:F1092	R:R:H1016	21.7661	3.39	No	No	0	9	9
41	R:R:F1092	R:R:M929	22.5563	3.73	No	Yes	0	9	9
42	R:R:I997	R:R:L993	10.6344	1.43	No	No	0	5	5
43	R:R:F1088	R:R:L1082	19.2877	6.09	Yes	Yes	4	8	8
44	R:R:L1082	R:R:W1081	25.4741	6.83	Yes	No	0	8	6
45	R:R:L1028	R:R:W1025	20.4633	5.69	No	Yes	0	7	9
46	R:R:G1030	R:R:L1154	25.6784	1.71	No	Yes	0	5	6
47	R:R:E1029	R:R:G1030	33.8113	1.64	Yes	No	0	9	5
48	R:R:I1035	R:R:Q1032	16.8555	8.23	No	Yes	0	7	8
49	R:R:F1051	R:R:Q1032	17.9194	2.34	No	Yes	0	5	8
50	R:R:F1051	R:R:L1028	19.0834	3.65	No	No	0	5	7
51	R:R:I1035	R:R:Y1034	15.3253	3.63	No	Yes	0	7	8
52	R:R:V1038	R:R:Y1034	10.8811	12.62	No	Yes	0	8	8
53	R:R:F1088	R:R:S1073	13.1013	5.28	Yes	No	0	8	9
54	R:R:F1190	R:R:I1189	11.1278	3.77	Yes	No	0	8	7
55	R:R:F1160	R:R:F1176	10.7308	3.22	Yes	Yes	3	8	9
56	R:R:L928	R:R:W1158	78.3611	2.28	Yes	Yes	0	9	8
57	R:R:M929	R:R:W1158	42.3489	4.65	Yes	Yes	3	9	8
58	R:R:F925	R:R:I953	35.0601	5.02	Yes	Yes	1	9	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 7WY8_nogp

PDB Summary
PDB	7WY8_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	2.28
Number of Linked Nodes	245
Number of Links	271
Number of Hubs	39
Number of Links mediated by Hubs	151
Number of Communities	9
Number of Nodes involved in Communities	48
Number of Links involved in Communities	60

Path Summary
Number Of Nodes in MetaPath	59
Number Of Links MetaPath	58
Number of Shortest Paths	45163
Length Of Smallest Path	3
Average Path Length	13.809
Length of Longest Path	27
Minimum Path Strength	1.31
Average Path Strength	4.71263
Maximum Path Strength	15.99
Minimum Path Correlation	0.7
Average Path Correlation	0.918916
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	4.54545
Average % Of Corr. Nodes	45.9057
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	46.2938
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• protein binding • binding • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development
Gene Ontology	Biological Process	• multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular process • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • signal transduction • cell communication • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • response to oxygen-containing compound • cellular response to oxygen-containing compound • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to chemical stimulus • cellular response to alcohol • response to hormone • response to chemical • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex
Gene Ontology	Cellular Component	• cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • membrane-bounded organelle • extracellular vesicle • extracellular organelle • extracellular region • organelle • extracellular space • vesicle • extracellular membrane-bounded organelle • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection • photoreceptor cell cilium • organelle membrane • intracellular anatomical structure • cytoplasm • cytosol • vacuolar membrane • lytic vacuole • vacuole • intracellular membrane-bounded organelle • intracellular organelle • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome • synapse • cell junction • protein binding • binding • G-protein beta-subunit binding • fibroblast proliferation • cell population proliferation • cellular process • cellular response to nitrogen compound • cellular response to stimulus • response to dopamine • regulation of cellular process • response to stimulus • signaling • cellular response to dopamine • response to monoamine • cell communication • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • signal transduction • regulation of biological process • G protein-coupled dopamine receptor signaling pathway • biological regulation • response to oxygen-containing compound • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to monoamine stimulus • response to chemical • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • response to hormone • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • cation binding • ion binding • calcium ion binding • metal ion binding • small molecule binding • molecular transducer activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • molecular condensate scaffold activity • protein-macromolecule adaptor activity • molecular adaptor activity • cell adhesion molecule binding • cell adhesion mediator activity • carbohydrate binding • developmental process • multicellular organismal process • nervous system development • excitatory synapse assembly • cellular component organization • cellular component biogenesis • multicellular organism development • cell junction organization • cellular component assembly • cell junction assembly • anatomical structure development • synapse organization • cellular component organization or biogenesis • synapse assembly • system development • positive regulation of nervous system development • positive regulation of cellular component organization • regulation of cellular component organization • regulation of developmental process • positive regulation of biological process • regulation of nervous system development • positive regulation of developmental process • regulation of multicellular organismal process • regulation of synapse structure or activity • regulation of synapse assembly • regulation of biological quality • positive regulation of cellular process • regulation of multicellular organismal development • positive regulation of cellular component biogenesis • regulation of cellular component biogenesis • regulation of cell junction assembly • positive regulation of cell junction assembly • regulation of synapse organization • positive regulation of multicellular organismal process • positive regulation of synapse assembly • cell surface receptor signaling pathway • Rho-activating G protein-coupled receptor signaling pathway • behavior • locomotory behavior • locomotion involved in locomotory behavior • locomotion • neuron migration • cellular developmental process • generation of neurons • neurogenesis • cell differentiation • cell migration • cell motility • response to cocaine • response to alkaloid • maintenance of synapse structure • postsynapse organization • cellular component maintenance • cell junction maintenance • organelle organization • maintenance of postsynaptic specialization structure • postsynaptic density organization • postsynaptic specialization organization • postsynapse • postsynaptic membrane • plasma membrane region • synaptic membrane • cell-cell junction • anchoring junction • glutamatergic synapse • Schaffer collateral - CA1 synapse • axon
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q80TS3
Sequence	>7WY8_nogp_Chain_R T N F A V L M A H V E V K H S D A V H D L L L D V I T W V G I L L S L V C L L I C I F T F C F F R G L Q S D R N T I H K N L C I S L F V A E L L F L I G I N R T D Q P I A C A V F A A L L H F F F L A A F T W M F L E G V Q L Y I M L V E V F E S E H S R R K Y F Y L V G Y G M P A L I V A V S A A V D Y R S Y G T D K V C W L R L D T Y F I W S F I G P A T L I I M L N V I F L G I A L Y K M F H H T W V I G A I A L L C L L G L T W A F G L M Y I N E S T V I M A Y L F T I F N S L Q G M F I F I F H C V L Q K K V R K E Y G K C L R T Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	7WY5	B2	Adhesion	Adhesion	ADGRL3	Mus musculus	-	-	chim(NtGi1-Gs-CtGq)/β1/γ2	2.83	2022-10-26	doi.org/10.1016/j.molcel.2022.10.009
	7WY5 (No Gprot)	B2	Adhesion	Adhesion	ADGRL3	Mus musculus	-	-		2.83	2022-10-26	doi.org/10.1016/j.molcel.2022.10.009
	7WY8	B2	Adhesion	Adhesion	ADGRL3	Mus musculus	-	-	chim(NtGi1-Gs)/β1/γ2	2.83	2022-10-26	doi.org/10.1016/j.molcel.2022.10.009
	7WY8 (No Gprot)	B2	Adhesion	Adhesion	ADGRL3	Mus musculus	-	-		2.83	2022-10-26	doi.org/10.1016/j.molcel.2022.10.009
	7WYB	B2	Adhesion	Adhesion	ADGRL3	Mus musculus	-	-	Gi1/β1/γ2	2.97	2022-10-26	doi.org/10.1016/j.molcel.2022.10.009
	7WYB (No Gprot)	B2	Adhesion	Adhesion	ADGRL3	Mus musculus	-	-		2.97	2022-10-26	doi.org/10.1016/j.molcel.2022.10.009
	7X10	B2	Adhesion	Adhesion	ADGRL3	Mus musculus	-	-	chim(NtGi1-G12)/β1/γ2	2.93	2022-10-26	doi.org/10.1016/j.molcel.2022.10.009
	7X10 (No Gprot)	B2	Adhesion	Adhesion	ADGRL3	Mus musculus	-	-		2.93	2022-10-26	doi.org/10.1016/j.molcel.2022.10.009
	7SF7	B2	Adhesion	Adhesion	ADGRL3	Homo sapiens	-	-	chim(NtGi2-G13)/β1/γ2	2.9	2022-04-27	doi.org/10.1038/s41586-022-04575-7
	7SF7 (No Gprot)	B2	Adhesion	Adhesion	ADGRL3	Homo sapiens	-	-		2.9	2022-04-27	doi.org/10.1038/s41586-022-04575-7
	8JMT	B2	Adhesion	Adhesion	ADGRL3	Homo sapiens	-	-	-	3.3	2023-09-06	doi.org/10.1038/s41589-023-01389-0

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 7WY8_nogp.zip

You can click to copy the link of this page to easily come back here later

or use this QR code to link and share this page.

You can also read or download a guide explaining the meaning of all files and numerical data.