Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index Hub Avg Int. Strength Num Of Links Community ConSurf
1R:R:F925 4.568549
2R:R:L928 4.1625449
3R:R:H936 5.188531
4R:R:H941 5.69405
5R:R:L960 3.7975409
6R:R:F967 6.775429
7R:R:L973 2.665428
8R:R:N978 4.7675409
9R:R:N983 9.2875419
10R:R:H1016 4.7625409
11R:R:F1017 4.935408
12R:R:L1020 4.48409
13R:R:W1025 6.75714719
14R:R:E1029 5.565409
15R:R:P1059 3.29833609
16R:R:S1073 6.93409
17R:R:Y1074 3.698579
18R:R:W1081 6.565406
19R:R:F1088 8.5175478
20R:R:W1090 2.765407
21R:R:L1156 3.132506
22R:R:Y1164 5.04436
23R:R:E1167 3.2575435
24R:R:Y1174 2.91409
25R:R:T1177 2.6625409
26R:R:N1180 10.655409
27R:R:F1188 5.76407
28R:R:F1190 4.46588
29R:R:Y1202 10.074527
   

Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index Node1 Node2 Recurrence Int. Strength Hub1? Hub2? Community ConSurf1 ConSurf2
1R:R:F925 R:R:T949 53.39586.49YesNo098
2R:R:T1177 R:R:T949 52.15563.14YesNo098
3R:R:L945 R:R:T1177 10.26872.95NoYes089
4R:R:F925 R:R:L928 90.10782.44YesYes499
5R:R:F925 R:R:I953 47.59343.77YesNo099
6R:R:F925 R:R:S1181 16.8022.64YesNo097
7R:R:L928 R:R:W1081 95.1135.69YesYes096
8R:R:I1093 R:R:W1090 28.90892.35NoYes087
9R:R:I1089 R:R:W1090 35.73013.52NoYes097
10R:R:I1089 R:R:W1081 37.08112.35NoYes096
11R:R:I1093 R:R:M929 24.33932.92NoNo089
12R:R:F1176 R:R:M929 21.43817.46NoNo099
13R:R:H936 R:R:H941 15.82758.36YesYes015
14R:R:H941 R:R:Y1174 20.10934.36YesYes059
15R:R:I948 R:R:Y1174 40.3442.42NoYes099
16R:R:I948 R:R:T1177 41.71713.04NoYes099
17R:R:H936 R:R:V1170 15.96044.15YesNo014
18R:R:V1170 R:R:Y1174 17.47382.52NoYes049
19R:R:H936 R:R:Y1164 15.87923.27YesYes316
20R:R:E992 R:R:I953 42.24869.56NoNo099
21R:R:G952 R:R:V951 11.98141.84NoNo098
22R:R:G952 R:R:S1181 15.27391.86NoNo097
23R:R:L960 R:R:S956 14.30683YesNo099
24R:R:E992 R:R:S956 17.48127.19NoNo099
25R:R:E992 R:R:L957 23.77096.63NoNo099
26R:R:F967 R:R:H981 36.35025.66YesNo099
27R:R:E1029 R:R:H981 41.87959.85YesNo099
28R:R:E1029 R:R:I980 88.04075.47YesNo099
29R:R:I980 R:R:W1025 85.94424.7NoYes199
30R:R:G1055 R:R:W1025 98.19142.81NoYes089
31R:R:G1055 R:R:T1024 99.22493.64NoNo085
32R:R:P1059 R:R:T1024 99.71953.5YesNo095
33R:R:L1020 R:R:P1059 96.2354.93YesYes099
34R:R:H1016 R:R:L1020 97.47532.57YesYes099
35R:R:H1016 R:R:L1082 97.63772.57YesNo098
36R:R:L1082 R:R:W1081 10011.39NoYes086
37R:R:C985 R:R:L960 11.98143.17NoYes099
38R:R:C985 R:R:I964 10.3133.27NoNo097
39R:R:F967 R:R:T966 14.37327.78YesNo299
40R:R:T966 R:R:Y1202 13.11839.99NoYes297
41R:R:F967 R:R:N978 11.302210.87YesYes099
42R:R:G998 R:R:I997 16.8983.53NoNo095
43R:R:I997 R:R:L993 18.50731.43NoNo055
44R:R:L957 R:R:L993 20.10191.38NoNo095
45R:R:F1088 R:R:L1082 32.67393.65YesNo088
46R:R:N1180 R:R:W1158 10.31323.73YesNo098
47R:R:F1176 R:R:N1180 15.273913.29NoYes099
48R:R:F1106 R:R:V1031 11.73042.62NoNo069
49R:R:F1106 R:R:G1030 25.93394.52NoNo065
50R:R:E1029 R:R:G1030 43.45931.64YesNo095
51R:R:E1029 R:R:L1153 22.98835.3YesNo099
52R:R:G1030 R:R:L1033 17.711.71NoNo059
53R:R:L1033 R:R:L1150 13.16265.54NoNo099
54R:R:F1106 R:R:Y1034 13.51695.16NoNo068
55R:R:V1038 R:R:Y1034 10.335212.62NoNo088
56R:R:D1070 R:R:S1073 10.3137.36NoYes099
57R:R:F1088 R:R:S1073 24.79713.21YesYes089
58R:R:R1083 R:R:S1073 10.26133.95NoYes059
59R:R:L1107 R:R:L1156 10.24661.38NoYes086
60R:R:L1107 R:R:L1150 11.67874.15NoNo089
61R:R:F1190 R:R:I1148 10.09896.28YesNo085
62R:R:F1190 R:R:H1191 18.31543.39YesNo088
63R:R:H1191 R:R:L1153 19.72547.71NoNo089
Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


PDB Summary
PDB 7X10_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.
Net Summary
Imin 2.42
Number of Linked Nodes 236
Number of Links 253
Number of Hubs 29
Number of Links mediated by Hubs 112
Number of Communities 8
Number of Nodes involved in Communities 34
Number of Links involved in Communities 40
Path Summary
Number Of Nodes in MetaPath 64
Number Of Links MetaPath 63
Number of Shortest Paths 27909
Length Of Smallest Path 3
Average Path Length 14.4147
Length of Longest Path 30
Minimum Path Strength 1.14
Average Path Strength 4.79861
Maximum Path Strength 18.51
Minimum Path Correlation 0.7
Average Path Correlation 0.922753
Maximum Path Correlation 1
Minimum % Of Corr. Nodes 4
Average % Of Corr. Nodes 41.9773
Maximum % Of Corr. Nodes 100
Minimum Path Hubs % 0
Average Path Hubs % 41.1882
Maximum Path Hubs % 100
AnnotationTypeLinks
Gene OntologyMolecular Function
Gene OntologyBiological Process
Gene OntologyCellular Component
SCOP2Domain Identifier• Transducin (heterotrimeric G protein), gamma chain
SCOP2Family Identifier• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations-• Orientations of Proteins in Membranes database (OPM)   • Protein Data Bank of Transmembrane Proteins (PDBTM)   • MemProtMD


Details about the values in these tables can be found in the corresponding documentation page .
PDBsumOpen PDBsum Page
ChainR
ProteinReceptor
UniProtQ80TS3
Sequence
>7X10_nogp_Chain_R
TNFAVLMAH VEVKHSDAV HDLLLDVIT WVGILLSLV CLLICIFTF 
CFFRGLQSD RNTIHKNLC ISLFVAELL FLIGINRTD QPIACAVFA 
ALLHFFFLA AFTWMFLEG VQLYIMLVE VFESEHSRR KYFYLVGYG 
MPALIVAVS AAVDYRSYG TDKVCWLRL DTYFIWSFI GPATLIIML 
NVIFLGIAL YKMFHHTWV IGAIALLCL LGLTWAFGL MYINESTVI 
MAYLFTIFN SLQGMFIFI FHCVLQKKV RKEYGKCLR T


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  




This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
8JMTB2AdhesionAdhesionADGRL3Homo sapiens---3.32023-09-0610.1038/s41589-023-01389-0
7X10B2AdhesionAdhesionADGRL3Mus musculus--chim(NtGi1-G12)/β1/γ22.932022-10-2610.1016/j.molcel.2022.10.009
7X10 (No Gprot) B2AdhesionAdhesionADGRL3Mus musculus--2.932022-10-2610.1016/j.molcel.2022.10.009
7WY5B2AdhesionAdhesionADGRL3Mus musculus--chim(NtGi1-Gs-CtGq)/β1/γ22.832022-10-2610.1016/j.molcel.2022.10.009
7WY5 (No Gprot) B2AdhesionAdhesionADGRL3Mus musculus--2.832022-10-2610.1016/j.molcel.2022.10.009
7WY8B2AdhesionAdhesionADGRL3Mus musculus--chim(NtGi1-Gs)/β1/γ22.832022-10-2610.1016/j.molcel.2022.10.009
7WY8 (No Gprot) B2AdhesionAdhesionADGRL3Mus musculus--2.832022-10-2610.1016/j.molcel.2022.10.009
7WYBB2AdhesionAdhesionADGRL3Mus musculus--Gi1/β1/γ22.972022-10-2610.1016/j.molcel.2022.10.009
7WYB (No Gprot) B2AdhesionAdhesionADGRL3Mus musculus--2.972022-10-2610.1016/j.molcel.2022.10.009
7SF7B2AdhesionAdhesionADGRL3Homo sapiens--chim(NtGi2-G13)/β1/γ22.92022-04-2710.1038/s41586-022-04575-7
7SF7 (No Gprot) B2AdhesionAdhesionADGRL3Homo sapiens--2.92022-04-2710.1038/s41586-022-04575-7




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Download 7X10_nogp.zip



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