psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:D258	R:R:M259	4.16	Yes	No	1	4	4
2	R:R:D258	R:R:T291	5.78	Yes	No	0	4	3
3	R:R:A294	R:R:D258	1.54	No	Yes	1	6	4
4	R:R:D258	R:R:L341	2.71	Yes	Yes	1	4	7
5	R:R:D258	R:R:S344	8.83	Yes	No	1	4	4
6	R:R:K343	R:R:M259	1.44	No	No	1	5	4
7	R:R:M259	R:R:S344	1.53	No	No	1	4	4
8	R:R:F261	R:R:G286	9.03	No	No	0	6	3
9	R:R:S262	R:R:W264	2.47	No	Yes	1	5	4
10	R:R:D336	R:R:S262	5.89	No	No	1	3	5
11	R:R:I340	R:R:S262	3.1	No	No	1	3	5
12	R:R:T263	R:R:T265	1.57	No	No	0	3	4
13	R:R:Q283	R:R:T263	4.25	No	No	0	4	3
14	R:R:F278	R:R:W264	4.01	Yes	Yes	1	6	4
15	R:R:F279	R:R:W264	8.02	Yes	Yes	1	4	4
16	R:R:V282	R:R:W264	13.48	No	Yes	1	6	4
17	R:R:V301	R:R:W264	3.68	No	Yes	1	5	4
18	R:R:N333	R:R:W264	22.6	No	Yes	1	3	4
19	R:R:L334	R:R:W264	3.42	Yes	Yes	1	7	4
20	R:R:I337	R:R:W264	4.7	No	Yes	0	5	4
21	R:R:P266	R:R:T265	1.75	Yes	No	0	1	4
22	R:R:P266	R:R:P267	1.95	Yes	Yes	1	1	4
23	R:R:L275	R:R:P266	3.28	Yes	Yes	1	4	1
24	R:R:F279	R:R:P266	8.67	Yes	Yes	1	4	1
25	R:R:P267	R:R:P268	1.95	Yes	No	0	4	3
26	R:R:P267	R:R:V270	7.07	Yes	Yes	1	4	3
27	R:R:L325	R:R:P267	6.57	No	Yes	0	3	4
28	R:R:I326	R:R:P267	3.39	Yes	Yes	1	4	4
29	R:R:P267	R:R:Q329	1.58	Yes	No	1	4	4
30	R:R:L318	R:R:V270	1.49	No	Yes	1	6	3
31	R:R:V270	R:R:V322	3.21	Yes	Yes	1	3	3
32	R:R:I326	R:R:V270	3.07	Yes	Yes	1	4	3
33	R:R:H271	R:R:Q273	4.95	No	No	0	3	4
34	R:R:S272	R:R:T274	1.6	Yes	Yes	1	5	4
35	R:R:L275	R:R:S272	3	Yes	Yes	1	4	5
36	R:R:D314	R:R:S272	8.83	No	Yes	1	8	5
37	R:R:S272	R:R:V315	1.62	Yes	Yes	0	5	5
38	R:R:L308	R:R:T274	1.47	No	Yes	0	5	4
39	R:R:G313	R:R:T274	1.82	No	Yes	1	3	4
40	R:R:D314	R:R:T274	2.89	No	Yes	1	8	4
41	R:R:F279	R:R:L275	9.74	Yes	Yes	1	4	4
42	R:R:I326	R:R:L275	4.28	Yes	Yes	1	4	4
43	R:R:D280	R:R:R277	5.96	No	No	0	3	1
44	R:R:K281	R:R:R277	2.48	No	No	0	4	1
45	R:R:F278	R:R:F279	8.57	Yes	Yes	1	6	4
46	R:R:F278	R:R:V282	7.87	Yes	No	1	6	6
47	R:R:F278	R:R:L304	2.44	Yes	No	1	6	3
48	R:R:F278	R:R:V305	2.62	Yes	Yes	1	6	5
49	R:R:F278	R:R:L308	9.74	Yes	No	0	6	5
50	R:R:F278	R:R:L330	3.65	Yes	No	1	6	6
51	R:R:F279	R:R:L330	2.44	Yes	No	1	4	6
52	R:R:K281	R:R:L304	4.23	No	No	0	4	3
53	R:R:E307	R:R:K281	4.05	No	No	0	3	4
54	R:R:L304	R:R:V282	1.49	No	No	1	3	6
55	R:R:D284	R:R:R287	14.29	No	No	0	3	4
56	R:R:G286	R:R:L285	1.71	No	Yes	0	3	8
57	R:R:L285	R:R:T297	4.42	Yes	Yes	0	8	6
58	R:R:L285	R:R:N300	8.24	Yes	No	0	8	3
59	R:R:L285	R:R:V301	1.49	Yes	No	0	8	5
60	R:R:G286	R:R:S289	1.86	No	No	0	3	2
61	R:R:D288	R:R:R287	14.29	No	No	0	3	4
62	R:R:S289	R:R:T297	9.59	No	Yes	0	2	6
63	R:R:K290	R:R:S292	1.53	No	No	4	2	3
64	R:R:K290	R:R:S293	3.06	No	Yes	4	2	4
65	R:R:S292	R:R:S293	1.63	No	Yes	4	3	4
66	R:R:S293	R:R:V296	8.08	Yes	No	0	4	1
67	R:R:S293	R:R:T297	1.6	Yes	Yes	0	4	6
68	R:R:A294	R:R:L341	6.3	No	Yes	1	6	7
69	R:R:A294	R:R:L345	1.58	No	Yes	1	6	6
70	R:R:E295	R:R:V296	5.7	Yes	No	0	3	1
71	R:R:E295	R:R:Q299	8.92	Yes	No	1	3	5
72	R:R:E295	R:R:L345	3.98	Yes	Yes	1	3	6
73	R:R:E295	R:R:Y352	14.59	Yes	No	1	3	4
74	R:R:L341	R:R:T297	2.95	Yes	Yes	0	7	6
75	R:R:I298	R:R:I302	1.47	Yes	Yes	1	6	4
76	R:R:I298	R:R:M338	1.46	Yes	Yes	1	6	7
77	R:R:I298	R:R:L341	5.71	Yes	Yes	1	6	7
78	R:R:I298	R:R:L360	1.43	Yes	Yes	1	6	7
79	R:R:Q299	R:R:Y352	23.67	No	No	1	5	4
80	R:R:K303	R:R:N300	4.2	No	No	0	4	3
81	R:R:L334	R:R:V301	1.49	Yes	No	1	7	5
82	R:R:D306	R:R:I302	4.2	Yes	Yes	1	7	4
83	R:R:I302	R:R:S354	1.55	Yes	Yes	1	4	6
84	R:R:I302	R:R:T358	4.56	Yes	Yes	1	4	8
85	R:R:I302	R:R:L360	2.85	Yes	Yes	1	4	7
86	R:R:I302	R:R:L402	1.43	Yes	Yes	1	4	5
87	R:R:D306	R:R:V305	1.46	Yes	Yes	1	7	5
88	R:R:M309	R:R:V305	1.52	Yes	Yes	1	8	5
89	R:R:L334	R:R:V305	2.98	Yes	Yes	1	7	5
90	R:R:D306	R:R:M309	4.16	Yes	Yes	1	7	8
91	R:R:D306	R:R:S354	5.89	Yes	Yes	1	7	6
92	R:R:D306	R:R:S356	10.31	Yes	Yes	1	7	5
93	R:R:D306	R:R:T358	7.23	Yes	Yes	1	7	8
94	R:R:I404	R:R:M309	2.92	Yes	Yes	1	6	8
95	R:R:M309	R:R:M407	2.89	Yes	Yes	1	8	7
96	R:R:M309	R:R:T409	1.51	Yes	Yes	1	8	4
97	R:R:E310	R:R:S356	4.31	No	Yes	0	7	5
98	R:R:A311	R:R:P312	1.87	No	Yes	0	4	6
99	R:R:E316	R:R:P312	6.29	No	Yes	1	4	6
100	R:R:P312	R:R:T409	3.5	Yes	Yes	1	6	4
101	H:H:?2	R:R:P312	2.95	Yes	Yes	1	0	6
102	R:R:D314	R:R:G313	1.68	No	No	1	8	3
103	R:R:E316	R:R:V315	2.85	No	Yes	0	4	5
104	R:R:R323	R:R:V315	2.62	No	Yes	0	5	5
105	R:R:L410	R:R:V315	1.49	No	Yes	0	6	5
106	R:R:E316	R:R:T409	2.82	No	Yes	1	4	4
107	R:R:L318	R:R:V322	4.47	No	Yes	1	6	3
108	R:R:I326	R:R:L318	1.43	Yes	No	1	4	6
109	R:R:A319	R:R:P320	1.87	No	Yes	1	3	1
110	R:R:A319	R:R:P321	1.87	No	No	1	3	4
111	R:R:A319	R:R:V322	3.39	No	Yes	1	3	3
112	R:R:P320	R:R:P321	5.84	Yes	No	1	1	4
113	R:R:P320	R:R:R323	10.09	Yes	No	0	1	5
114	R:R:H324	R:R:P320	1.53	No	Yes	0	5	1
115	R:R:P321	R:R:R504	7.21	No	No	0	4	3
116	R:R:I326	R:R:V322	3.07	Yes	Yes	1	4	3
117	R:R:A414	R:R:H324	2.93	No	No	0	8	5
118	R:R:H324	R:R:W498	5.29	No	Yes	0	5	7
119	R:R:G505	R:R:L325	3.42	No	No	0	4	3
120	R:R:I326	R:R:L330	2.85	Yes	No	1	4	6
121	R:R:A327	R:R:L410	4.73	No	No	0	8	6
122	R:R:A327	R:R:L411	1.58	No	Yes	0	8	6
123	R:R:T328	R:R:W498	12.13	No	Yes	0	7	7
124	R:R:S500	R:R:T328	1.6	No	No	0	4	7
125	R:R:Q329	R:R:S332	4.33	No	No	1	4	2
126	R:R:N333	R:R:Q329	10.56	No	No	1	3	4
127	R:R:L331	R:R:S332	1.5	No	No	1	9	2
128	R:R:L331	R:R:W498	3.42	No	Yes	1	9	7
129	R:R:L331	R:R:S532	4.5	No	No	1	9	9
130	R:R:N333	R:R:S332	2.98	No	No	1	3	2
131	R:R:I404	R:R:L334	1.43	Yes	Yes	1	6	7
132	R:R:E335	R:R:R339	8.14	No	No	0	9	5
133	R:R:E335	R:R:S447	7.19	No	No	0	9	8
134	R:R:D336	R:R:I340	8.4	No	No	1	3	3
135	R:R:I337	R:R:M338	1.46	No	Yes	0	5	7
136	R:R:I337	R:R:L341	4.28	No	Yes	0	5	7
137	R:R:L360	R:R:M338	4.24	Yes	Yes	1	7	7
138	R:R:L402	R:R:M338	4.24	Yes	Yes	1	5	7
139	R:R:M338	R:R:S447	1.53	Yes	No	1	7	8
140	R:R:F449	R:R:M338	9.95	Yes	Yes	1	7	7
141	R:R:F449	R:R:R339	10.69	Yes	No	0	7	5
142	R:R:L341	R:R:S344	1.5	Yes	No	1	7	4
143	R:R:A342	R:R:V398	5.09	No	No	0	7	5
144	R:R:K343	R:R:V398	1.52	No	No	1	5	5
145	R:R:K343	R:R:S451	1.53	No	No	1	5	8
146	R:R:L345	R:R:P346	3.28	Yes	No	1	6	5
147	R:R:F350	R:R:L345	14.61	Yes	Yes	1	5	6
148	R:R:I364	R:R:L345	1.43	Yes	Yes	1	7	6
149	R:R:F350	R:R:P346	2.89	Yes	No	1	5	5
150	R:R:I364	R:R:K347	2.91	Yes	No	0	7	2
151	R:R:E366	R:R:K347	13.5	No	No	0	5	2
152	R:R:G348	R:R:P349	4.06	No	No	1	4	3
153	R:R:G348	R:R:M363	1.75	No	Yes	1	4	5
154	R:R:M363	R:R:P349	6.71	Yes	No	1	5	3
155	R:R:F350	R:R:Y352	7.22	Yes	No	1	5	4
156	R:R:F350	R:R:L362	6.09	Yes	Yes	1	5	6
157	R:R:F350	R:R:I364	5.02	Yes	Yes	1	5	7
158	R:R:T351	R:R:T361	4.71	No	No	0	5	6
159	R:R:Q376	R:R:T351	8.5	No	No	0	6	5
160	R:R:P355	R:R:S354	3.56	No	Yes	0	4	6
161	R:R:S354	R:R:S356	1.63	Yes	Yes	1	6	5
162	R:R:S354	R:R:T358	6.4	Yes	Yes	1	6	8
163	R:R:Q405	R:R:S356	1.44	No	Yes	0	4	5
164	R:R:L402	R:R:T358	1.47	Yes	Yes	1	5	8
165	R:R:I404	R:R:T358	7.6	Yes	Yes	1	6	8
166	R:R:Q405	R:R:T358	4.25	No	Yes	0	4	8
167	R:R:E359	R:R:T361	2.82	Yes	No	0	5	6
168	R:R:E359	R:R:S377	10.06	Yes	No	1	5	6
169	R:R:E359	R:R:S378	5.75	Yes	Yes	1	5	5
170	R:R:E359	R:R:S403	2.87	Yes	Yes	1	5	8
171	R:R:L360	R:R:L362	9.69	Yes	Yes	1	7	6
172	R:R:L360	R:R:L402	6.92	Yes	Yes	1	7	5
173	R:R:G400	R:R:L362	1.71	No	Yes	1	8	6
174	R:R:F449	R:R:L362	2.44	Yes	Yes	1	7	6
175	R:R:M363	R:R:Q365	4.08	Yes	No	1	5	4
176	R:R:M363	R:R:M374	7.22	Yes	No	0	5	7
177	R:R:M363	R:R:W385	2.33	Yes	Yes	1	5	6
178	R:R:I364	R:R:P396	1.69	Yes	No	0	7	4
179	R:R:Q365	R:R:V372	4.3	No	Yes	1	4	6
180	R:R:Q365	R:R:W385	16.43	No	Yes	1	4	6
181	R:R:G368	R:R:R367	1.5	No	No	0	5	4
182	R:R:A389	R:R:R367	9.68	No	No	0	5	4
183	R:R:D369	R:R:G368	1.68	No	No	0	3	5
184	R:R:K370	R:R:V372	3.04	No	Yes	0	4	6
185	R:R:N371	R:R:N384	4.09	No	No	0	5	5
186	R:R:M374	R:R:V372	4.56	No	Yes	0	7	6
187	R:R:L383	R:R:V372	1.49	Yes	Yes	1	7	6
188	R:R:V372	R:R:W385	9.81	Yes	Yes	1	6	6
189	R:R:K382	R:R:T373	9.01	No	No	0	4	6
190	R:R:G375	R:R:M374	1.75	No	No	0	6	7
191	R:R:G375	R:R:R380	3	No	No	0	6	4
192	R:R:S377	R:R:S378	1.63	No	Yes	1	6	5
193	R:R:A379	R:R:S378	1.71	No	Yes	1	7	5
194	R:R:S378	R:R:S403	6.52	Yes	Yes	1	5	8
195	R:R:S378	R:R:V445	3.23	Yes	Yes	1	5	9
196	R:R:A379	R:R:V445	1.7	No	Yes	1	7	9
197	R:R:A379	R:R:F466	2.77	No	Yes	1	7	7
198	R:R:L383	R:R:M381	12.72	Yes	Yes	1	7	8
199	R:R:I401	R:R:M381	4.37	Yes	Yes	1	8	8
200	R:R:I448	R:R:M381	2.92	Yes	Yes	1	7	8
201	R:R:I462	R:R:M381	4.37	Yes	Yes	1	9	8
202	R:R:F464	R:R:M381	9.95	Yes	Yes	1	7	8
203	R:R:L530	R:R:M381	2.83	Yes	Yes	1	9	8
204	R:R:L383	R:R:W385	5.69	Yes	Yes	1	7	6
205	R:R:I462	R:R:L383	5.71	Yes	Yes	1	9	7
206	R:R:A386	R:R:N384	3.13	No	No	0	5	5
207	R:R:A388	R:R:W385	9.08	Yes	Yes	1	8	6
208	R:R:A397	R:R:W385	5.19	No	Yes	1	6	6
209	R:R:A399	R:R:W385	2.59	No	Yes	1	7	6
210	R:R:L450	R:R:V387	2.98	Yes	No	0	7	6
211	R:R:N459	R:R:V387	2.96	No	No	0	5	6
212	R:R:I462	R:R:V387	1.54	Yes	No	0	9	6
213	R:R:A388	R:R:A397	1.79	Yes	No	1	8	6
214	R:R:A388	R:R:A399	1.79	Yes	No	1	8	7
215	R:R:A388	R:R:L450	1.58	Yes	Yes	1	8	7
216	R:R:A389	R:R:A397	1.79	No	No	0	5	6
217	R:R:G390	R:R:H452	4.77	No	Yes	0	5	8
218	R:R:A391	R:R:E392	1.51	No	No	0	5	3
219	R:R:D393	R:R:P394	6.44	No	No	0	5	5
220	R:R:D393	R:R:G395	1.68	No	No	0	5	7
221	R:R:D393	R:R:S451	2.94	No	No	0	5	8
222	R:R:G395	R:R:P396	4.06	No	No	0	7	4
223	R:R:S451	R:R:V398	6.46	No	No	1	8	5
224	R:R:A399	R:R:L450	1.58	No	Yes	1	7	7
225	R:R:G400	R:R:I401	1.76	No	Yes	1	8	8
226	R:R:F449	R:R:G400	6.02	Yes	No	1	7	8
227	R:R:I401	R:R:S403	1.55	Yes	Yes	1	8	8
228	R:R:I401	R:R:V445	1.54	Yes	Yes	1	8	9
229	R:R:I401	R:R:I448	8.83	Yes	Yes	1	8	7
230	R:R:I404	R:R:L402	7.14	Yes	Yes	1	6	5
231	R:R:L402	R:R:S447	4.5	Yes	No	1	5	8
232	R:R:A444	R:R:S403	1.71	No	Yes	0	6	8
233	R:R:S403	R:R:V445	6.46	Yes	Yes	1	8	9
234	R:R:I404	R:R:M407	4.37	Yes	Yes	1	6	7
235	R:R:I404	R:R:N446	2.83	Yes	No	1	6	7
236	R:R:A444	R:R:Q405	1.52	No	No	0	6	4
237	R:R:N406	R:R:T408	5.85	No	No	0	5	4
238	R:R:N406	R:R:T409	5.85	No	Yes	1	5	4
239	H:H:?2	R:R:N406	30.8	Yes	No	1	0	5
240	R:R:L411	R:R:M407	5.65	Yes	Yes	1	6	7
241	R:R:M407	R:R:R441	2.48	Yes	No	0	7	6
242	R:R:M407	R:R:N446	7.01	Yes	No	1	7	7
243	R:R:R441	R:R:T408	6.47	No	No	0	6	4
244	H:H:?2	R:R:T409	3.97	Yes	Yes	1	0	4
245	R:R:L411	R:R:W498	5.69	Yes	Yes	1	6	7
246	R:R:L411	R:R:W508	3.42	Yes	Yes	1	6	8
247	H:H:?1	R:R:N413	36.96	No	No	0	0	5
248	R:R:A414	R:R:L439	1.58	No	Yes	1	8	3
249	R:R:A414	R:R:W508	2.59	No	Yes	1	8	8
250	R:R:L416	R:R:L418	5.54	Yes	Yes	1	5	4
251	R:R:L416	R:R:V437	7.45	Yes	Yes	1	5	5
252	R:R:L416	R:R:L439	5.54	Yes	Yes	1	5	3
253	R:R:L416	R:R:L494	4.15	Yes	Yes	1	5	5
254	R:R:L416	R:R:W508	2.28	Yes	Yes	1	5	8
255	R:R:L416	R:R:T510	1.47	Yes	No	1	5	6
256	R:R:H507	R:R:N417	12.75	Yes	No	0	5	3
257	R:R:L418	R:R:Q423	5.32	Yes	No	0	4	4
258	R:R:L418	R:R:L426	2.77	Yes	Yes	0	4	6
259	R:R:L418	R:R:V437	1.49	Yes	Yes	1	4	5
260	R:R:H419	R:R:S420	8.37	No	No	0	3	3
261	R:R:H419	R:R:K421	11.79	No	No	0	3	3
262	R:R:K422	R:R:L426	11.28	Yes	Yes	0	3	6
263	R:R:E492	R:R:K422	4.05	No	Yes	0	4	3
264	R:R:E427	R:R:Q423	5.1	No	No	0	4	4
265	R:R:A424	R:R:E427	1.51	No	No	0	4	4
266	R:R:I434	R:R:L426	4.28	No	Yes	0	4	6
267	R:R:L426	R:R:Y540	7.03	Yes	Yes	0	6	6
268	R:R:I429	R:R:Y430	6.04	No	No	0	4	5
269	R:R:Y430	R:R:Y540	4.96	No	Yes	0	5	6
270	R:R:E431	R:R:R680	3.49	No	Yes	0	4	8
271	R:R:E431	R:R:R682	3.49	No	Yes	0	4	4
272	R:R:S432	R:R:S433	1.63	No	No	2	3	1
273	R:R:E543	R:R:S432	2.87	No	No	2	5	3
274	R:R:R682	R:R:S432	3.95	Yes	No	2	4	3
275	R:R:E543	R:R:S433	5.75	No	No	2	5	1
276	R:R:G436	R:R:I434	1.76	No	No	0	3	4
277	R:R:I434	R:R:V542	4.61	No	No	0	4	6
278	R:R:G436	R:R:R435	1.5	No	No	0	3	3
279	R:R:D541	R:R:R435	10.72	No	No	0	5	3
280	R:R:L439	R:R:V437	2.98	Yes	Yes	1	3	5
281	R:R:A538	R:R:V437	1.7	No	Yes	1	9	5
282	R:R:V437	R:R:Y540	8.83	Yes	Yes	1	5	6
283	R:R:H539	R:R:Q438	14.84	No	No	0	6	5
284	R:R:D541	R:R:Q438	5.22	No	No	0	5	5
285	R:R:L439	R:R:W508	3.42	Yes	Yes	1	3	8
286	R:R:A538	R:R:L439	1.58	No	Yes	1	9	3
287	R:R:H468	R:R:L442	2.57	No	No	0	9	6
288	R:R:I535	R:R:L442	2.85	Yes	No	0	8	6
289	R:R:L442	R:R:M537	9.9	No	No	0	6	9
290	R:R:S443	R:R:V445	1.62	No	Yes	0	9	9
291	R:R:A534	R:R:S443	1.71	No	No	0	9	9
292	R:R:I535	R:R:S443	6.19	Yes	No	0	8	9
293	R:R:F466	R:R:V445	9.18	Yes	Yes	1	7	9
294	R:R:F464	R:R:I448	3.77	Yes	Yes	1	7	7
295	R:R:F466	R:R:I448	2.51	Yes	Yes	1	7	7
296	R:R:I448	R:R:L530	1.43	Yes	Yes	1	7	9
297	R:R:F533	R:R:I448	5.02	Yes	Yes	1	9	7
298	R:R:H452	R:R:L450	2.57	Yes	Yes	1	8	7
299	R:R:L450	R:R:T455	4.42	Yes	No	1	7	9
300	R:R:L450	R:R:L530	4.15	Yes	Yes	1	7	9
301	R:R:H452	R:R:N454	2.55	Yes	No	0	8	5
302	R:R:H452	R:R:T455	2.74	Yes	No	1	8	9
303	R:R:K456	R:R:N454	5.6	No	No	0	4	5
304	R:R:L530	R:R:T455	2.95	Yes	No	1	9	9
305	R:R:I462	R:R:L458	5.71	Yes	No	1	9	9
306	R:R:L458	R:R:L530	9.69	No	Yes	1	9	9
307	R:R:N459	R:R:S460	1.49	No	No	0	5	5
308	R:R:P461	R:R:S460	3.56	No	No	0	5	5
309	R:R:P461	R:R:Q526	6.32	No	No	0	5	5
310	R:R:F464	R:R:I462	8.79	Yes	Yes	1	7	9
311	R:R:I462	R:R:L530	1.43	Yes	Yes	1	9	9
312	R:R:L463	R:R:Q526	5.32	No	No	0	5	5
313	R:R:F464	R:R:F466	9.65	Yes	Yes	1	7	7
314	R:R:C527	R:R:F464	6.98	No	Yes	1	8	7
315	R:R:F464	R:R:L530	2.44	Yes	Yes	1	7	9
316	R:R:F464	R:R:F533	3.22	Yes	Yes	1	7	9
317	R:R:C525	R:R:F466	2.79	Yes	Yes	1	9	7
318	R:R:F466	R:R:F533	4.29	Yes	Yes	1	7	9
319	R:R:F466	R:R:I535	8.79	Yes	Yes	1	7	8
320	R:R:A482	R:R:H468	4.39	No	No	5	4	9
321	R:R:G521	R:R:H468	4.77	No	No	5	5	9
322	R:R:L469	R:R:S471	1.5	No	No	0	3	4
323	R:R:A482	R:R:E470	6.03	No	No	0	4	2
324	H:H:?2	R:R:S471	2.69	Yes	No	0	0	4
325	R:R:D473	R:R:S472	1.47	No	No	0	2	2
326	R:R:G474	R:R:S472	1.86	No	No	0	5	2
327	R:R:D479	R:R:S472	8.83	No	No	0	3	2
328	R:R:E475	R:R:R478	11.63	No	No	0	6	3
329	R:R:D479	R:R:P480	4.83	No	No	0	3	7
330	R:R:P480	R:R:P481	1.95	No	No	0	7	4
331	H:H:?3	R:R:P481	1.47	No	No	0	0	4
332	R:R:A482	R:R:G521	1.95	No	No	5	4	5
333	R:R:D484	R:R:G521	1.68	No	No	0	2	5
334	R:R:M537	R:R:V485	3.04	No	No	0	9	3
335	R:R:M486	R:R:P487	5.03	No	No	0	4	4
336	R:R:P487	R:R:Q491	1.58	No	No	0	4	4
337	R:R:G488	R:R:P489	4.06	No	No	0	4	3
338	R:R:P489	R:R:Q607	9.47	No	No	0	3	4
339	R:R:H539	R:R:R490	12.41	No	No	0	6	3
340	R:R:G606	R:R:R490	1.5	No	No	0	6	3
341	R:R:M537	R:R:Q491	14.95	No	No	0	9	4
342	R:R:E492	R:R:L494	5.3	No	Yes	1	4	5
343	R:R:E492	R:R:Y540	10.1	No	Yes	1	4	6
344	R:R:L493	R:R:V515	1.49	Yes	No	0	6	3
345	R:R:L493	R:R:S518	1.5	Yes	No	1	6	8
346	R:R:L493	R:R:T523	5.9	Yes	Yes	1	6	9
347	R:R:I535	R:R:L493	2.85	Yes	Yes	1	8	6
348	R:R:A496	R:R:L494	3.15	No	Yes	1	8	5
349	R:R:L494	R:R:T510	4.42	Yes	No	1	5	6
350	R:R:L494	R:R:L536	9.69	Yes	Yes	1	5	9
351	R:R:A538	R:R:L494	4.73	No	Yes	1	9	5
352	R:R:L494	R:R:Y540	3.52	Yes	Yes	1	5	6
353	R:R:C495	R:R:C513	1.82	Yes	No	1	9	9
354	R:R:C495	R:R:V515	3.42	Yes	No	0	9	3
355	R:R:C495	R:R:T523	1.69	Yes	Yes	1	9	9
356	R:R:C495	R:R:C525	7.28	Yes	Yes	1	9	9
357	R:R:C495	R:R:I535	3.27	Yes	Yes	1	9	8
358	R:R:A496	R:R:T510	1.68	No	No	1	8	6
359	R:R:A496	R:R:L536	3.15	No	Yes	1	8	9
360	R:R:F497	R:R:K499	4.96	Yes	No	0	6	3
361	R:R:A509	R:R:F497	5.55	No	Yes	0	8	6
362	R:R:E511	R:R:F497	5.83	No	Yes	0	4	6
363	R:R:F497	R:R:S531	5.28	Yes	No	0	6	9
364	R:R:F497	R:R:F533	5.36	Yes	Yes	0	6	9
365	R:R:G506	R:R:W498	4.22	Yes	Yes	1	8	7
366	R:R:W498	R:R:W508	17.81	Yes	Yes	1	7	8
367	R:R:S532	R:R:W498	2.47	No	Yes	1	9	7
368	R:R:K499	R:R:S500	1.53	No	No	0	3	4
369	R:R:D501	R:R:S502	1.47	Yes	No	0	4	4
370	R:R:D501	R:R:D503	6.65	Yes	No	0	4	4
371	R:R:D501	R:R:G506	1.68	Yes	Yes	1	4	8
372	R:R:D501	R:R:H507	7.56	Yes	Yes	1	4	5
373	R:R:D503	R:R:R504	2.38	No	No	0	4	3
374	R:R:G505	R:R:G506	2.11	No	Yes	0	4	8
375	R:R:G506	R:R:H507	1.59	Yes	Yes	1	8	5
376	R:R:A509	R:R:H507	1.46	No	Yes	0	8	5
377	R:R:A534	R:R:W508	2.59	No	Yes	1	9	8
378	R:R:L536	R:R:W508	7.97	Yes	Yes	1	9	8
379	R:R:E511	R:R:G512	1.64	No	No	0	4	9
380	R:R:G512	R:R:S528	3.71	No	No	0	9	5
381	R:R:C513	R:R:C527	7.28	No	No	1	9	8
382	R:R:C513	R:R:F533	4.19	No	Yes	1	9	9
383	R:R:L516	R:R:Q514	3.99	No	No	0	5	2
384	R:R:Q514	R:R:Q526	8.96	No	No	0	2	5
385	R:R:L516	R:R:T524	5.9	No	No	0	5	7
386	R:R:G517	R:R:S518	3.71	No	No	0	1	8
387	R:R:S518	R:R:T523	7.99	No	Yes	1	8	9
388	H:H:?3	R:R:K519	2.53	No	No	0	0	4
389	H:H:?3	R:R:N520	29.57	No	No	0	0	6
390	R:R:C525	R:R:T523	1.69	Yes	Yes	1	9	9
391	R:R:I535	R:R:T523	3.04	Yes	Yes	1	8	9
392	R:R:C525	R:R:I535	1.64	Yes	Yes	1	9	8
393	R:R:C527	R:R:F533	6.98	No	Yes	1	8	9
394	R:R:F533	R:R:L530	2.44	Yes	Yes	1	9	9
395	R:R:S531	R:R:S532	1.63	No	No	0	9	9
396	R:R:A534	R:R:L536	1.58	No	Yes	1	9	9
397	R:R:E543	R:R:V542	1.43	No	No	0	5	6
398	R:R:D544	R:R:K546	12.44	No	No	0	8	4
399	R:R:D544	R:R:G605	3.35	No	No	0	8	7
400	R:R:L547	R:R:W545	4.56	Yes	Yes	2	9	5
401	R:R:I601	R:R:W545	7.05	Yes	Yes	2	7	5
402	R:R:R682	R:R:W545	2	Yes	Yes	2	4	5
403	R:R:W545	R:R:Y683	2.89	Yes	Yes	2	5	6
404	R:R:F760	R:R:W545	10.02	Yes	Yes	2	8	5
405	R:R:L547	R:R:T551	1.47	Yes	Yes	0	9	9
406	R:R:L547	R:R:R552	13.36	Yes	No	0	9	5
407	R:R:I601	R:R:L547	4.28	Yes	Yes	2	7	9
408	R:R:I550	R:R:T548	4.56	No	No	0	8	4
409	R:R:T548	R:R:T551	1.57	No	Yes	0	4	9
410	R:R:L765	R:R:T548	1.47	No	No	0	3	4
411	R:R:L549	R:R:V553	1.49	No	No	0	5	7
412	R:R:I550	R:R:Y769	4.84	No	No	0	8	9
413	R:R:I550	R:R:T772	3.04	No	Yes	0	8	9
414	R:R:L555	R:R:T551	1.47	Yes	Yes	0	9	9
415	R:R:T551	R:R:T768	3.14	Yes	No	0	9	7
416	R:R:T551	R:R:T772	4.71	Yes	Yes	0	9	9
417	R:R:L598	R:R:R552	3.64	No	No	0	9	5
418	R:R:E602	R:R:R552	4.65	No	No	0	7	5
419	R:R:G554	R:R:V553	1.84	Yes	No	3	9	7
420	R:R:L557	R:R:V553	2.98	No	No	3	6	7
421	R:R:G554	R:R:L557	1.71	Yes	No	3	9	6
422	R:R:G554	R:R:T772	1.82	Yes	Yes	3	9	9
423	R:R:C776	R:R:G554	1.96	No	Yes	3	8	9
424	R:R:L555	R:R:S558	1.5	Yes	No	2	9	9
425	R:R:F597	R:R:L555	4.87	Yes	Yes	2	9	9
426	R:R:L555	R:R:L598	8.3	Yes	No	0	9	9
427	R:R:L555	R:R:N775	4.12	Yes	Yes	2	9	9
428	R:R:C776	R:R:L557	1.59	No	No	3	8	6
429	R:R:S558	R:R:S594	1.63	No	No	0	9	8
430	R:R:N775	R:R:S558	2.98	Yes	No	2	9	9
431	R:R:F591	R:R:L559	12.18	Yes	No	2	9	8
432	R:R:L559	R:R:S594	3	No	No	0	8	8
433	R:R:L559	R:R:T595	5.9	No	No	2	8	6
434	R:R:F560	R:R:L564	9.74	No	No	0	5	8
435	R:R:C561	R:R:G779	3.92	No	No	0	9	9
436	R:R:C587	R:R:L562	3.17	Yes	No	0	8	9
437	R:R:L562	R:R:L590	5.54	No	Yes	0	9	9
438	R:R:F591	R:R:L562	3.65	Yes	No	0	9	9
439	R:R:F591	R:R:L563	6.09	Yes	No	0	9	5
440	R:R:L564	R:R:Y783	9.38	No	Yes	0	8	9
441	R:R:C565	R:R:F569	2.79	Yes	Yes	2	7	9
442	R:R:C565	R:R:C587	5.46	Yes	Yes	2	7	8
443	R:R:C565	R:R:L782	1.59	Yes	Yes	2	7	8
444	R:R:C565	R:R:Y783	4.03	Yes	Yes	2	7	9
445	R:R:C565	R:R:C787	1.82	Yes	Yes	2	7	9
446	R:R:I566	R:R:L570	2.85	Yes	No	2	9	6
447	R:R:I566	R:R:L584	2.85	Yes	Yes	2	9	9
448	R:R:C587	R:R:I566	3.27	Yes	Yes	2	8	9
449	R:R:I566	R:R:I588	5.89	Yes	Yes	2	9	7
450	R:R:F591	R:R:I566	3.77	Yes	Yes	2	9	9
451	R:R:T568	R:R:V572	3.17	Yes	Yes	2	9	9
452	R:R:C787	R:R:T568	6.76	Yes	Yes	2	9	9
453	R:R:T568	R:R:V793	4.76	Yes	Yes	2	9	9
454	R:R:T568	R:R:Y797	12.48	Yes	Yes	2	9	9
455	R:R:F569	R:R:I575	2.51	Yes	Yes	2	9	9
456	R:R:F569	R:R:T580	3.89	Yes	No	2	9	9
457	R:R:F569	R:R:H583	5.66	Yes	Yes	2	9	9
458	R:R:F569	R:R:L584	6.09	Yes	Yes	2	9	9
459	R:R:C587	R:R:F569	2.79	Yes	Yes	2	8	9
460	R:R:F569	R:R:H786	3.39	Yes	Yes	2	9	9
461	R:R:C787	R:R:F569	5.59	Yes	Yes	2	9	9
462	R:R:L570	R:R:L584	6.92	No	Yes	2	6	9
463	R:R:L571	R:R:W800	4.56	No	Yes	0	7	6
464	R:R:P574	R:R:V572	3.53	Yes	Yes	2	8	9
465	R:R:I575	R:R:V572	9.22	Yes	Yes	2	9	9
466	R:R:V572	R:R:V793	1.6	Yes	Yes	2	9	9
467	R:R:E796	R:R:V572	8.56	Yes	Yes	2	8	9
468	R:R:V572	R:R:W800	3.68	Yes	Yes	2	9	6
469	R:R:P574	R:R:R573	1.44	Yes	No	0	8	8
470	R:R:Q576	R:R:R573	11.68	No	No	0	8	8
471	R:R:K792	R:R:P574	5.02	Yes	Yes	2	9	8
472	R:R:E796	R:R:P574	4.72	Yes	Yes	2	8	8
473	R:R:I575	R:R:T580	7.6	Yes	No	2	9	9
474	R:R:I575	R:R:N790	4.25	Yes	No	2	9	9
475	R:R:I575	R:R:K792	4.36	Yes	Yes	2	9	9
476	R:R:I575	R:R:V793	3.07	Yes	Yes	2	9	9
477	R:R:E636	R:R:S578	2.87	Yes	No	2	7	8
478	R:R:L655	R:R:S578	1.5	Yes	No	2	7	8
479	R:R:H583	R:R:R579	7.9	Yes	Yes	2	9	9
480	R:R:E633	R:R:R579	11.63	Yes	Yes	2	9	9
481	R:R:L637	R:R:R579	3.64	Yes	Yes	2	9	9
482	R:R:L738	R:R:R579	7.29	No	Yes	2	9	9
483	R:R:H585	R:R:T581	2.74	Yes	No	0	9	9
484	R:R:T581	R:R:T652	6.28	No	No	0	9	6
485	R:R:L655	R:R:T581	1.47	Yes	No	0	7	9
486	R:R:I582	R:R:W629	5.87	Yes	Yes	2	8	9
487	R:R:I582	R:R:L632	2.85	Yes	Yes	2	8	9
488	R:R:E633	R:R:I582	4.1	Yes	Yes	2	9	8
489	R:R:E636	R:R:I582	4.1	Yes	Yes	2	7	8
490	R:R:I582	R:R:L655	5.71	Yes	Yes	2	8	7
491	R:R:E633	R:R:H583	13.54	Yes	Yes	2	9	9
492	R:R:H583	R:R:H786	25.08	Yes	Yes	2	9	9
493	R:R:I588	R:R:L584	2.85	Yes	Yes	2	7	9
494	R:R:H585	R:R:W629	17.98	Yes	Yes	2	9	9
495	R:R:C656	R:R:H585	4.42	No	Yes	2	4	9
496	R:R:H585	R:R:Y660	13.07	Yes	Yes	2	9	9
497	R:R:L586	R:R:L590	4.15	No	Yes	2	9	9
498	R:R:A626	R:R:L586	1.58	No	No	2	8	9
499	R:R:L586	R:R:Q745	2.66	No	Yes	2	9	9
500	R:R:C587	R:R:L782	3.17	Yes	Yes	2	8	8
501	R:R:I588	R:R:V592	1.54	Yes	No	2	7	6
502	R:R:I588	R:R:Y660	2.42	Yes	Yes	2	7	9
503	R:R:A625	R:R:C589	3.61	No	Yes	2	9	8
504	R:R:A626	R:R:C589	1.81	No	Yes	2	8	8
505	R:R:C589	R:R:W629	2.61	Yes	Yes	2	8	9
506	R:R:C589	R:R:Y660	5.38	Yes	Yes	2	8	9
507	R:R:A626	R:R:L590	3.15	No	Yes	2	8	9
508	R:R:L590	R:R:Q778	9.32	Yes	Yes	0	9	9
509	R:R:F591	R:R:T595	5.19	Yes	No	2	9	6
510	R:R:I596	R:R:V592	3.07	Yes	No	2	6	6
511	R:R:C622	R:R:V592	3.42	No	No	2	7	6
512	R:R:C622	R:R:G593	3.92	No	No	0	7	9
513	R:R:I596	R:R:V615	3.07	Yes	Yes	2	6	8
514	R:R:I596	R:R:L618	4.28	Yes	No	0	6	8
515	R:R:I596	R:R:L619	7.14	Yes	Yes	2	6	9
516	R:R:C622	R:R:I596	1.64	No	Yes	2	7	6
517	R:R:F597	R:R:I601	20.09	Yes	Yes	2	9	7
518	R:R:F597	R:R:L619	4.87	Yes	Yes	2	9	9
519	R:R:F597	R:R:I759	2.51	Yes	Yes	2	9	8
520	R:R:F597	R:R:F760	4.29	Yes	Yes	2	9	8
521	R:R:F597	R:R:F771	2.14	Yes	Yes	2	9	9
522	R:R:G600	R:R:R611	4.5	No	No	2	8	7
523	R:R:G600	R:R:V615	3.68	No	Yes	2	8	8
524	R:R:I601	R:R:L619	1.43	Yes	Yes	2	7	9
525	R:R:F760	R:R:I601	3.77	Yes	Yes	2	8	7
526	R:R:E602	R:R:E604	2.54	No	No	0	7	8
527	R:R:C612	R:R:N603	6.3	Yes	No	2	9	6
528	R:R:C684	R:R:N603	6.3	No	No	2	9	6
529	R:R:G605	R:R:G606	2.11	No	No	0	7	6
530	R:R:C612	R:R:V608	3.42	Yes	Yes	2	9	6
531	R:R:R613	R:R:V608	5.23	No	Yes	0	6	6
532	R:R:G679	R:R:V608	1.84	No	Yes	2	9	6
533	R:R:P681	R:R:V608	3.53	No	Yes	0	3	6
534	R:R:L610	R:R:L614	4.15	No	No	0	6	5
535	R:R:R611	R:R:V615	2.62	No	Yes	2	7	8
536	R:R:C612	R:R:G679	1.96	Yes	No	2	9	9
537	R:R:C612	R:R:C684	7.28	Yes	No	2	9	9
538	R:R:L619	R:R:V615	2.98	Yes	Yes	2	9	8
539	R:R:C684	R:R:V615	3.42	No	Yes	2	9	8
540	R:R:A616	R:R:G617	1.95	Yes	No	2	9	8
541	R:R:A616	R:R:Y678	2.67	Yes	Yes	2	9	9
542	R:R:A616	R:R:G679	1.95	Yes	No	2	9	9
543	R:R:A616	R:R:L686	1.58	Yes	Yes	2	9	9
544	R:R:G617	R:R:Y678	2.9	No	Yes	2	8	9
545	R:R:L619	R:R:W685	3.42	Yes	Yes	2	9	9
546	R:R:H620	R:R:L624	9	Yes	Yes	2	9	9
547	R:R:H620	R:R:V667	5.54	Yes	Yes	2	9	9
548	R:R:H620	R:R:S670	2.79	Yes	No	2	9	9
549	R:R:H620	R:R:Y678	6.53	Yes	Yes	2	9	9
550	R:R:H620	R:R:L686	5.14	Yes	Yes	2	9	9
551	R:R:F696	R:R:H620	6.79	Yes	Yes	2	9	9
552	R:R:A625	R:R:Y621	2.67	No	Yes	2	9	6
553	R:R:Y621	R:R:Y660	4.96	Yes	Yes	2	6	9
554	R:R:P663	R:R:Y621	2.78	Yes	Yes	2	9	6
555	R:R:L664	R:R:Y621	5.86	No	Yes	0	8	6
556	R:R:V667	R:R:Y621	2.52	Yes	Yes	2	9	6
557	R:R:F623	R:R:L624	6.09	Yes	Yes	2	8	9
558	R:R:F623	R:R:F696	4.29	Yes	Yes	2	8	9
559	R:R:F623	R:R:V700	3.93	Yes	No	2	8	8
560	R:R:F623	R:R:W753	22.05	Yes	Yes	2	8	9
561	R:R:L624	R:R:P663	3.28	Yes	Yes	2	9	9
562	R:R:I666	R:R:L624	5.71	No	Yes	0	8	9
563	R:R:L624	R:R:V667	1.49	Yes	Yes	2	9	9
564	R:R:A625	R:R:P663	3.74	No	Yes	2	9	9
565	R:R:F627	R:R:S631	2.64	Yes	No	2	9	7
566	R:R:F627	R:R:V700	2.62	Yes	No	2	9	8
567	R:R:F627	R:R:I703	13.82	Yes	Yes	2	9	9
568	R:R:F627	R:R:I704	7.54	Yes	No	0	9	6
569	R:R:F627	R:R:N707	3.62	Yes	Yes	2	9	9
570	R:R:F627	R:R:L746	2.44	Yes	Yes	2	9	7
571	R:R:C628	R:R:G659	1.96	Yes	Yes	2	7	9
572	R:R:C628	R:R:V662	1.71	Yes	Yes	2	7	7
573	R:R:C628	R:R:P663	7.53	Yes	Yes	2	7	9
574	R:R:C628	R:R:I703	1.64	Yes	Yes	2	7	9
575	R:R:L632	R:R:W629	6.83	Yes	Yes	2	9	9
576	R:R:L655	R:R:W629	4.56	Yes	Yes	2	7	9
577	R:R:C656	R:R:W629	2.61	No	Yes	2	4	9
578	R:R:G659	R:R:W629	7.04	Yes	Yes	2	9	9
579	R:R:W629	R:R:Y660	12.54	Yes	Yes	2	9	9
580	R:R:E633	R:R:M630	6.77	Yes	Yes	2	9	9
581	R:R:A742	R:R:M630	1.61	Yes	Yes	2	9	9
582	R:R:M630	R:R:Q745	13.59	Yes	Yes	2	9	9
583	R:R:L746	R:R:M630	4.24	Yes	Yes	2	7	9
584	R:R:I703	R:R:S631	3.1	Yes	No	2	9	7
585	R:R:N707	R:R:S631	10.43	Yes	No	2	9	7
586	R:R:L632	R:R:L655	6.92	Yes	Yes	2	9	7
587	R:R:I658	R:R:L632	8.56	No	Yes	2	6	9
588	R:R:G659	R:R:L632	1.71	Yes	Yes	2	9	9
589	R:R:E633	R:R:G634	1.64	Yes	Yes	0	9	9
590	R:R:A742	R:R:E633	3.02	Yes	Yes	2	9	9
591	R:R:E633	R:R:Q745	5.1	Yes	Yes	2	9	9
592	R:R:G634	R:R:L637	1.71	Yes	Yes	0	9	9
593	R:R:G634	R:R:I710	1.76	Yes	No	0	9	7
594	R:R:F711	R:R:G634	3.01	Yes	Yes	0	8	9
595	R:R:F639	R:R:L635	10.96	No	No	0	8	7
596	R:R:I710	R:R:L635	4.28	No	No	0	7	7
597	R:R:E636	R:R:G649	1.64	Yes	No	0	7	7
598	R:R:E636	R:R:L650	7.95	Yes	No	2	7	5
599	R:R:E636	R:R:L655	5.3	Yes	Yes	2	7	7
600	R:R:L637	R:R:L738	6.92	Yes	No	2	9	9
601	R:R:L637	R:R:T739	1.47	Yes	Yes	2	9	9
602	R:R:A742	R:R:L637	1.58	Yes	Yes	2	9	9
603	R:R:F639	R:R:Y638	5.16	No	Yes	0	8	8
604	R:R:V642	R:R:Y638	8.83	No	Yes	0	9	8
605	R:R:T713	R:R:Y638	7.49	No	Yes	0	6	8
606	R:R:T714	R:R:Y638	3.75	Yes	Yes	0	9	8
607	R:R:F639	R:R:R643	2.14	No	Yes	0	8	7
608	R:R:L640	R:R:R643	2.43	No	Yes	0	6	7
609	R:R:F645	R:R:L640	6.09	No	No	0	9	6
610	R:R:F645	R:R:V641	2.62	No	Yes	2	9	9
611	R:R:T714	R:R:V641	4.76	Yes	Yes	2	9	9
612	R:R:K717	R:R:V641	1.52	No	Yes	2	8	9
613	R:R:L718	R:R:V641	7.45	Yes	Yes	2	8	9
614	R:R:A735	R:R:V641	1.7	No	Yes	2	8	9
615	R:R:G647	R:R:R643	3	No	Yes	0	5	7
616	R:R:G649	R:R:R643	4.5	No	Yes	0	7	7
617	R:R:Q646	R:R:V644	5.73	No	No	0	7	9
618	R:R:A735	R:R:F645	2.77	No	No	2	8	9
619	R:R:G647	R:R:Q646	1.64	No	No	0	5	7
620	R:R:L650	R:R:W654	2.28	No	Yes	0	5	6
621	R:R:L650	R:R:L655	2.77	No	Yes	2	5	7
622	R:R:S651	R:R:W654	8.65	No	Yes	0	6	6
623	R:R:C656	R:R:T652	1.69	No	No	0	4	6
624	R:R:R653	R:R:W654	10	No	Yes	0	5	6
625	R:R:L657	R:R:W654	2.28	No	Yes	0	7	6
626	R:R:G659	R:R:I658	3.53	Yes	No	2	9	6
627	R:R:I658	R:R:V662	1.54	No	Yes	2	6	7
628	R:R:G659	R:R:P663	2.03	Yes	Yes	2	9	9
629	R:R:G661	R:R:P663	2.03	No	Yes	0	9	9
630	R:R:G661	R:R:L664	1.71	No	No	0	9	8
631	R:R:P663	R:R:V662	3.53	Yes	Yes	2	9	7
632	R:R:I666	R:R:V662	3.07	No	Yes	0	8	7
633	R:R:I666	R:R:P699	6.77	No	No	0	8	9
634	R:R:S670	R:R:V667	1.62	No	Yes	2	9	9
635	R:R:I673	R:R:V669	3.07	No	No	0	5	7
636	R:R:S670	R:R:Y678	5.09	No	Yes	2	9	9
637	R:R:A671	R:R:Y678	4	No	Yes	0	8	9
638	R:R:I673	R:R:Y674	13.3	No	No	0	5	5
639	R:R:F692	R:R:Y674	12.38	Yes	No	0	8	5
640	R:R:S695	R:R:Y674	8.9	No	No	0	8	5
641	R:R:G677	R:R:K676	1.74	No	No	0	8	3
642	R:R:K676	R:R:Q690	4.07	No	No	0	3	2
643	R:R:L686	R:R:Y678	7.03	Yes	Yes	2	9	9
644	R:R:F692	R:R:Y678	5.16	Yes	Yes	2	8	9
645	R:R:P681	R:R:R680	1.44	No	Yes	0	3	8
646	R:R:R680	R:R:Y683	14.4	Yes	Yes	0	8	6
647	R:R:D687	R:R:R680	16.68	No	Yes	0	5	8
648	R:R:R682	R:R:Y683	8.23	Yes	Yes	2	4	6
649	R:R:W685	R:R:Y683	5.79	Yes	Yes	2	9	6
650	R:R:F760	R:R:Y683	24.76	Yes	Yes	2	8	6
651	R:R:L686	R:R:W685	13.67	Yes	Yes	2	9	9
652	R:R:F696	R:R:W685	3.01	Yes	Yes	2	9	9
653	R:R:L757	R:R:W685	3.42	No	Yes	0	5	9
654	R:R:F760	R:R:W685	6.01	Yes	Yes	2	8	9
655	R:R:F688	R:R:L686	3.65	Yes	Yes	2	4	9
656	R:R:F692	R:R:L686	7.31	Yes	Yes	2	8	9
657	R:R:F696	R:R:L686	3.65	Yes	Yes	2	9	9
658	R:R:D687	R:R:E689	3.9	No	No	0	5	3
659	R:R:F688	R:R:F692	5.36	Yes	Yes	2	4	8
660	R:R:F688	R:R:L693	12.18	Yes	No	0	4	7
661	R:R:F688	R:R:F696	10.72	Yes	Yes	2	4	9
662	R:R:L693	R:R:L697	4.15	No	Yes	0	7	7
663	R:R:F696	R:R:L697	3.65	Yes	Yes	2	9	7
664	R:R:F696	R:R:W753	6.01	Yes	Yes	2	9	9
665	R:R:L697	R:R:T701	1.47	Yes	No	0	7	7
666	R:R:L697	R:R:W753	2.28	Yes	Yes	2	7	9
667	R:R:G698	R:R:P699	4.06	No	No	0	8	9
668	R:R:V700	R:R:W753	3.68	No	Yes	2	8	9
669	R:R:C706	R:R:F702	6.98	No	No	0	5	4
670	R:R:F711	R:R:N707	4.83	Yes	Yes	2	8	9
671	R:R:L746	R:R:N707	8.24	Yes	Yes	2	7	9
672	R:R:T713	R:R:V709	1.59	No	No	0	6	5
673	R:R:I710	R:R:T714	1.52	No	Yes	0	7	9
674	R:R:F711	R:R:T739	2.59	Yes	Yes	2	8	9
675	R:R:A742	R:R:F711	2.77	Yes	Yes	2	9	8
676	R:R:F711	R:R:I743	12.56	Yes	No	2	8	6
677	R:R:F711	R:R:L746	2.44	Yes	Yes	2	8	7
678	R:R:T713	R:R:V712	1.59	No	No	0	6	7
679	R:R:L718	R:R:T714	1.47	Yes	Yes	2	8	9
680	R:R:T714	R:R:T739	4.71	Yes	Yes	2	9	9
681	R:R:T719	R:R:V715	1.59	No	No	0	8	6
682	R:R:T739	R:R:V715	1.59	Yes	No	0	9	6
683	R:R:K717	R:R:W716	2.32	No	No	2	8	8
684	R:R:T719	R:R:W716	2.43	No	No	0	8	8
685	R:R:Q720	R:R:W716	9.86	No	No	2	5	8
686	R:R:K717	R:R:Q720	5.42	No	No	2	8	5
687	R:R:A735	R:R:L718	1.58	No	Yes	2	8	8
688	R:R:L718	R:R:R736	6.07	Yes	No	0	8	8
689	R:R:L718	R:R:T739	2.95	Yes	Yes	2	8	9
690	R:R:I743	R:R:T739	1.52	No	Yes	2	6	9
691	R:R:F781	R:R:T741	2.59	Yes	No	2	8	9
692	R:R:L785	R:R:T741	5.9	No	No	2	8	9
693	R:R:F747	R:R:I743	3.77	No	No	0	5	6
694	R:R:A744	R:R:F781	2.77	No	Yes	0	9	8
695	R:R:F781	R:R:Q745	5.86	Yes	Yes	2	8	9
696	R:R:L782	R:R:Q745	7.99	Yes	Yes	2	8	9
697	R:R:H786	R:R:Q745	9.89	Yes	Yes	2	9	9
698	R:R:F781	R:R:L748	3.65	Yes	No	0	8	8
699	R:R:G750	R:R:L749	1.71	No	No	0	9	9
700	R:R:L749	R:R:Q778	9.32	No	Yes	0	9	9
701	R:R:C751	R:R:L774	1.59	No	Yes	0	5	7
702	R:R:F771	R:R:T752	2.59	Yes	Yes	2	9	9
703	R:R:L774	R:R:T752	8.84	Yes	Yes	2	7	9
704	R:R:N775	R:R:T752	4.39	Yes	Yes	2	9	9
705	R:R:Q778	R:R:T752	5.67	Yes	Yes	0	9	9
706	R:R:V754	R:R:W753	4.9	No	Yes	0	6	9
707	R:R:L757	R:R:W753	12.53	No	Yes	0	5	9
708	R:R:F755	R:R:L767	8.53	No	Yes	0	8	7
709	R:R:F755	R:R:V770	9.18	No	No	2	8	6
710	R:R:F755	R:R:L774	3.65	No	Yes	2	8	7
711	R:R:F771	R:R:G756	6.02	Yes	No	0	9	9
712	R:R:F758	R:R:L757	2.44	No	No	0	8	5
713	R:R:F758	R:R:L767	3.65	No	Yes	0	8	7
714	R:R:F760	R:R:I759	11.3	Yes	Yes	2	8	8
715	R:R:I759	R:R:L767	1.43	Yes	Yes	0	8	7
716	R:R:I759	R:R:T768	4.56	Yes	No	0	8	7
717	R:R:F771	R:R:I759	6.28	Yes	Yes	2	9	8
718	R:R:D762	R:R:L767	4.07	No	Yes	0	5	7
719	R:R:S764	R:R:V766	1.62	No	No	0	7	6
720	R:R:L765	R:R:T768	8.84	No	No	0	3	7
721	R:R:L774	R:R:V770	2.98	Yes	No	2	7	6
722	R:R:F771	R:R:N775	12.08	Yes	Yes	2	9	9
723	R:R:C776	R:R:T772	1.69	No	Yes	3	8	9
724	R:R:I773	R:R:L777	2.85	No	No	0	8	8
725	R:R:G779	R:R:Q778	1.64	No	Yes	0	9	9
726	R:R:F781	R:R:L785	13.4	Yes	No	2	8	8
727	R:R:H786	R:R:L782	2.57	Yes	Yes	2	9	8
728	R:R:C787	R:R:Y783	8.06	Yes	Yes	2	9	9
729	R:R:L788	R:R:Y783	7.03	No	Yes	0	8	9
730	R:R:Y783	R:R:Y797	4.96	Yes	Yes	2	9	9
731	R:R:L784	R:R:L785	2.77	No	No	0	5	8
732	R:R:L784	R:R:L788	4.15	No	No	0	5	8
733	R:R:L784	R:R:L789	6.92	No	No	0	5	8
734	R:R:C787	R:R:V793	1.71	Yes	Yes	2	9	9
735	R:R:K792	R:R:N790	4.2	Yes	No	2	9	9
736	R:R:N790	R:R:V793	10.35	No	Yes	2	9	9
737	R:R:K791	R:R:R794	4.95	No	No	0	8	8
738	R:R:V793	R:R:Y797	8.83	Yes	Yes	2	9	9
739	R:R:R794	R:R:R798	4.26	No	No	0	8	4
740	R:R:E796	R:R:K799	8.1	Yes	No	0	8	5
741	R:R:E796	R:R:W800	14.17	Yes	Yes	2	8	6
742	R:R:W800	R:R:Y797	5.79	Yes	Yes	2	6	9
743	R:R:I353	R:R:N357	1.42	No	No	0	3	4
744	R:R:H507	R:R:S415	1.39	Yes	No	0	5	6
745	R:R:A412	R:R:R323	1.38	No	No	0	6	5
746	R:R:A465	R:R:R380	1.38	No	No	0	7	4
747	R:R:D484	R:R:K519	1.38	No	No	0	2	4
748	R:R:L567	R:R:L571	1.38	No	No	0	7	7
749	R:R:E359	R:R:I353	1.37	Yes	No	0	5	3
750	R:R:L469	R:R:N357	1.37	No	No	0	3	4
751	R:R:D369	R:R:N384	1.35	No	No	0	3	5
752	R:R:E425	R:R:K422	1.35	No	Yes	0	4	3
753	R:R:E457	R:R:K456	1.35	No	No	0	5	4
754	R:R:E470	R:R:K483	1.35	No	No	0	2	3
755	R:R:E795	R:R:K792	1.35	No	Yes	0	6	9
756	R:R:H419	R:R:K422	1.31	No	Yes	0	3	3
757	R:R:H452	R:R:N453	1.28	Yes	No	0	8	4
758	R:R:E689	R:R:Q690	1.27	No	No	0	3	2
759	R:R:F702	R:R:I703	1.26	No	Yes	0	4	9
760	R:R:D761	R:R:F760	1.19	No	Yes	0	4	8
761	R:R:L693	R:R:W694	1.14	No	No	0	7	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:D258	4.604	5	1	4
2	R:R:W264	7.7975	8	1	4
3	R:R:P266	3.9125	4	1	1
4	R:R:P267	3.75167	6	1	4
5	R:R:V270	3.71	4	1	3
6	R:R:S272	3.7625	4	1	5
7	R:R:T274	1.945	4	1	4
8	R:R:L275	5.075	4	1	4
9	R:R:F278	5.55714	7	1	6
10	R:R:F279	7.488	5	1	4
11	R:R:L285	3.965	4	0	8
12	R:R:S293	3.5925	4	4	4
13	R:R:E295	8.2975	4	1	3
14	R:R:T297	4.64	4	0	6
15	R:R:I298	2.5175	4	1	6
16	R:R:I302	2.67667	6	1	4
17	R:R:V305	2.145	4	1	5
18	R:R:D306	5.54167	6	1	7
19	R:R:M309	2.6	5	1	8
20	R:R:P312	3.6525	4	1	6
21	R:R:V315	2.145	4	0	5
22	R:R:P320	4.8325	4	1	1
23	R:R:V322	3.535	4	1	3
24	R:R:I326	3.015	6	1	4
25	R:R:L334	2.33	4	1	7
26	R:R:M338	3.81333	6	1	7
27	R:R:L341	3.90833	6	1	7
28	R:R:L345	4.976	5	1	6
29	R:R:F350	7.166	5	1	5
30	R:R:S354	3.806	5	1	6
31	R:R:S356	4.4225	4	1	5
32	R:R:T358	5.25167	6	1	8
33	R:R:E359	4.574	5	1	5
34	R:R:L360	5.026	5	1	7
35	R:R:L362	4.9825	4	1	6
36	R:R:M363	4.418	5	1	5
37	R:R:I364	2.7625	4	1	7
38	R:R:V372	4.64	5	1	6
39	R:R:S378	3.768	5	1	5
40	R:R:M381	6.19333	6	1	8
41	R:R:L383	6.4025	4	1	7
42	R:R:W385	7.30286	7	1	6
43	R:R:A388	3.56	4	1	8
44	R:R:I401	3.61	5	1	8
45	R:R:L402	4.28333	6	1	5
46	R:R:S403	3.822	5	1	8
47	R:R:I404	4.38167	6	1	6
48	R:R:M407	4.48	5	1	7
49	R:R:T409	3.53	5	1	4
50	R:R:L411	4.085	4	1	6
51	R:R:L416	4.405	6	1	5
52	R:R:L418	3.78	4	1	4
53	R:R:K422	4.4975	4	0	3
54	R:R:L426	6.34	4	0	6
55	R:R:V437	4.49	5	1	5
56	R:R:L439	3.02	5	1	3
57	R:R:V445	3.955	6	1	9
58	R:R:I448	4.08	6	1	7
59	R:R:F449	7.275	4	1	7
60	R:R:L450	2.88	6	1	7
61	R:R:H452	2.782	5	1	8
62	R:R:I462	4.59167	6	1	9
63	R:R:F464	6.4	7	1	7
64	R:R:F466	5.71143	7	1	7
65	R:R:L493	2.935	4	1	6
66	R:R:L494	4.99429	7	1	5
67	R:R:C495	3.496	5	1	9
68	R:R:F497	5.396	5	0	6
69	R:R:W498	7.29	7	1	7
70	R:R:D501	4.34	4	1	4
71	R:R:G506	2.4	4	1	8
72	R:R:H507	4.95	5	1	5
73	R:R:W508	5.72571	7	1	8
74	R:R:T523	4.062	5	1	9
75	R:R:C525	3.35	4	1	9
76	R:R:L530	3.42	8	1	9
77	R:R:F533	4.5	7	1	9
78	R:R:I535	4.09	7	1	8
79	R:R:L536	5.5975	4	1	9
80	R:R:Y540	6.888	5	1	6
81	R:R:W545	5.304	5	2	5
82	R:R:L547	5.9175	4	2	9
83	R:R:T551	2.472	5	0	9
84	R:R:G554	1.8325	4	3	9
85	R:R:L555	4.052	5	2	9
86	R:R:C565	3.138	5	2	7
87	R:R:I566	3.726	5	2	9
88	R:R:T568	6.7925	4	2	9
89	R:R:F569	4.08875	8	2	9
90	R:R:V572	4.96	6	2	9
91	R:R:P574	3.6775	4	2	8
92	R:R:I575	5.16833	6	2	9
93	R:R:R579	7.615	4	2	9
94	R:R:I582	4.526	5	2	8
95	R:R:H583	13.045	4	2	9
96	R:R:L584	4.6775	4	2	9
97	R:R:H585	9.5525	4	2	9
98	R:R:C587	3.572	5	2	8
99	R:R:I588	3.175	4	2	7
100	R:R:C589	3.3525	4	2	8
101	R:R:L590	5.54	4	2	9
102	R:R:F591	6.176	5	2	9
103	R:R:I596	3.84	5	2	6
104	R:R:F597	6.46167	6	2	9
105	R:R:I601	7.324	5	2	7
106	R:R:V608	3.505	4	2	6
107	R:R:C612	4.74	4	2	9
108	R:R:V615	3.154	5	2	8
109	R:R:A616	2.0375	4	2	9
110	R:R:L619	3.968	5	2	9
111	R:R:H620	5.965	6	2	9
112	R:R:Y621	3.758	5	2	6
113	R:R:F623	9.09	4	2	8
114	R:R:L624	5.114	5	2	9
115	R:R:F627	5.44667	6	2	9
116	R:R:C628	3.21	4	2	7
117	R:R:W629	7.505	8	2	9
118	R:R:M630	6.5525	4	2	9
119	R:R:L632	5.374	5	2	9
120	R:R:E633	6.54286	7	2	9
121	R:R:G634	2.03	4	0	9
122	R:R:E636	4.372	5	2	7
123	R:R:L637	3.064	5	2	9
124	R:R:Y638	6.3075	4	0	8
125	R:R:V641	3.61	5	2	9
126	R:R:R643	3.0175	4	0	7
127	R:R:W654	5.8025	4	0	6
128	R:R:L655	4.03286	7	2	7
129	R:R:G659	3.254	5	2	9
130	R:R:Y660	7.674	5	2	9
131	R:R:V662	2.4625	4	2	7
132	R:R:P663	3.56	7	2	9
133	R:R:V667	2.7925	4	2	9
134	R:R:Y678	4.76857	7	2	9
135	R:R:R680	9.0025	4	0	8
136	R:R:R682	4.4175	4	2	4
137	R:R:Y683	11.214	5	2	6
138	R:R:W685	5.88667	6	2	9
139	R:R:L686	6.00429	7	2	9
140	R:R:F688	7.9775	4	2	4
141	R:R:F692	7.5525	4	2	8
142	R:R:F696	5.44571	7	2	9
143	R:R:L697	2.8875	4	2	7
144	R:R:I703	4.955	4	2	9
145	R:R:N707	6.78	4	2	9
146	R:R:F711	4.7	6	2	8
147	R:R:T714	3.242	5	2	9
148	R:R:L718	3.904	5	2	8
149	R:R:T739	2.47167	6	2	9
150	R:R:A742	2.245	4	2	9
151	R:R:Q745	7.515	6	2	9
152	R:R:L746	4.34	4	2	7
153	R:R:T752	5.3725	4	2	9
154	R:R:W753	8.575	6	2	9
155	R:R:I759	5.216	5	2	8
156	R:R:F760	8.76286	7	2	8
157	R:R:L767	4.42	4	0	7
158	R:R:F771	5.822	5	2	9
159	R:R:T772	2.815	4	3	9
160	R:R:L774	4.265	4	2	7
161	R:R:N775	5.8925	4	2	9
162	R:R:Q778	6.4875	4	0	9
163	R:R:F781	5.654	5	2	8
164	R:R:L782	3.83	4	2	8
165	R:R:Y783	6.692	5	2	9
166	R:R:H786	10.2325	4	2	9
167	R:R:C787	4.788	5	2	9
168	R:R:K792	3.7325	4	2	9
169	R:R:V793	5.05333	6	2	9
170	R:R:E796	8.8875	4	2	8
171	R:R:Y797	8.015	4	2	9
172	R:R:W800	7.05	4	2	6
173	H:H:?2	10.1025	4	1	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:I404	R:R:M407	16.2015	4.37	Yes	Yes	1	6	7
2	R:R:W498	R:R:W508	10.4294	17.81	Yes	Yes	1	7	8
3	R:R:L411	R:R:W508	22.546	3.42	Yes	Yes	1	6	8
4	R:R:L411	R:R:M407	21.4927	5.65	Yes	Yes	1	6	7
5	R:R:I401	R:R:M381	12.7043	4.37	Yes	Yes	1	8	8
6	R:R:I401	R:R:V445	20.2727	1.54	Yes	Yes	1	8	9
7	R:R:F466	R:R:V445	15.7643	9.18	Yes	Yes	1	7	9
8	R:R:I448	R:R:L530	12.0426	1.43	Yes	Yes	1	7	9
9	R:R:L450	R:R:L530	17.1568	4.15	Yes	Yes	1	7	9
10	R:R:H452	R:R:L450	11.3169	2.57	Yes	Yes	1	8	7
11	R:R:L530	R:R:T455	13.1668	2.95	Yes	No	1	9	9
12	R:R:H452	R:R:T455	11.2854	2.74	Yes	No	1	8	9
13	R:R:L416	R:R:W508	63.797	2.28	Yes	Yes	1	5	8
14	R:R:L416	R:R:L418	64.8805	5.54	Yes	Yes	1	5	4
15	R:R:L494	R:R:L536	30.9122	9.69	Yes	Yes	1	5	9
16	R:R:L418	R:R:L426	66.6456	2.77	Yes	Yes	0	4	6
17	R:R:I434	R:R:L426	99.856	4.28	No	Yes	0	4	6
18	R:R:L494	R:R:Y540	30.9562	3.52	Yes	Yes	1	5	6
19	R:R:I434	R:R:V542	99.966	4.61	No	No	0	4	6
20	R:R:E543	R:R:V542	99.9748	1.43	No	No	0	5	6
21	R:R:E543	R:R:S432	99.888	2.87	No	No	2	5	3
22	R:R:R682	R:R:S432	100	3.95	Yes	No	2	4	3
23	R:R:R682	R:R:Y683	76.5684	8.23	Yes	Yes	2	4	6
24	R:R:S443	R:R:V445	38.9664	1.62	No	Yes	0	9	9
25	R:R:I535	R:R:S443	23.1686	6.19	Yes	No	0	8	9
26	R:R:F466	R:R:I535	16.4338	8.79	Yes	Yes	1	7	8
27	R:R:A534	R:R:S443	61.4795	1.71	No	No	0	9	9
28	R:R:A534	R:R:W508	31.0521	2.59	No	Yes	1	9	8
29	R:R:H452	R:R:N454	11.3021	2.55	Yes	No	0	8	5
30	R:R:R682	R:R:W545	22.2969	2	Yes	Yes	2	4	5
31	R:R:I601	R:R:W545	13.1254	7.05	Yes	Yes	2	7	5
32	R:R:I601	R:R:L619	10.4927	1.43	Yes	Yes	2	7	9
33	R:R:I596	R:R:L619	19.3563	7.14	Yes	Yes	2	6	9
34	R:R:I596	R:R:V592	18.7195	3.07	Yes	No	2	6	6
35	R:R:I588	R:R:V592	18.5884	1.54	Yes	No	2	7	6
36	R:R:W685	R:R:Y683	70.0071	5.79	Yes	Yes	2	9	6
37	R:R:L619	R:R:W685	11.0526	3.42	Yes	Yes	2	9	9
38	R:R:W629	R:R:Y660	10.1324	12.54	Yes	Yes	2	9	9
39	R:R:L686	R:R:W685	12.0446	13.67	Yes	Yes	2	9	9
40	R:R:H620	R:R:L686	10.3724	5.14	Yes	Yes	2	9	9
41	R:R:F696	R:R:W685	39.2468	3.01	Yes	Yes	2	9	9
42	R:R:F696	R:R:H620	10.3455	6.79	Yes	Yes	2	9	9
43	R:R:H620	R:R:L624	12.899	9	Yes	Yes	2	9	9
44	R:R:L624	R:R:P663	17.2872	3.28	Yes	Yes	2	9	9
45	R:R:G659	R:R:P663	14.9635	2.03	Yes	Yes	2	9	9
46	R:R:F623	R:R:F696	17.4715	4.29	Yes	Yes	2	8	9
47	R:R:F623	R:R:V700	11.1157	3.93	Yes	No	2	8	8
48	R:R:F627	R:R:V700	32.817	2.62	Yes	No	2	9	8
49	R:R:F627	R:R:L746	17.7506	2.44	Yes	Yes	2	9	7
50	R:R:F696	R:R:W753	11.2625	6.01	Yes	Yes	2	9	9
51	R:R:V700	R:R:W753	22.0276	3.68	No	Yes	2	8	9
52	R:R:L757	R:R:W685	11.2397	3.42	No	Yes	0	5	9
53	R:R:L757	R:R:W753	11.1708	12.53	No	Yes	0	5	9
54	R:R:F627	R:R:N707	13.1613	3.62	Yes	Yes	2	9	9
55	R:R:F711	R:R:N707	12.8763	4.83	Yes	Yes	2	8	9
56	R:R:F711	R:R:L746	12.87	2.44	Yes	Yes	2	8	7
57	R:R:F711	R:R:T739	18.3927	2.59	Yes	Yes	2	8	9
58	R:R:E636	R:R:G649	12.1317	1.64	Yes	No	0	7	7
59	R:R:G649	R:R:R643	10.1246	4.5	No	Yes	0	7	7
60	R:R:A534	R:R:L536	30.6297	1.58	No	Yes	1	9	9
61	R:R:F533	R:R:L530	10.155	2.44	Yes	Yes	1	9	9
62	R:R:F464	R:R:F466	13.5641	9.65	Yes	Yes	1	7	7
63	R:R:L426	R:R:Y540	32.7306	7.03	Yes	Yes	0	6	6

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 8IKJ

PDB Summary
PDB	8IKJ
Class	B2
SubFamily	Adhesion
Type	Adhesion
SubType	ADGRE5
Species	Homo Sapiens
Ligand	-
Other Ligand(s)	-
Protein Partners	-
PDB Resolution	3.2
Date	2024-02-14
D.O.I.	doi.org/10.1016/j.molcel.2023.12.020

Net Summary
I_min	1.43
Number of Linked Nodes	505
Number of Links	761
Number of Hubs	173
Number of Links mediated by Hubs	570
Number of Communities	5
Number of Nodes involved in Communities	254
Number of Links involved in Communities	461

Path Summary
Number Of Nodes in MetaPath	64
Number Of Links MetaPath	63
Number of Shortest Paths	1220829
Length Of Smallest Path	3
Average Path Length	23.3122
Length of Longest Path	38
Minimum Path Strength	1.33
Average Path Strength	4.42993
Maximum Path Strength	19.58
Minimum Path Correlation	0.7
Average Path Correlation	0.977974
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	3.7037
Average % Of Corr. Nodes	56.2863
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	65.0362
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• binding • tetrapyrrole binding • heme binding • electron transfer activity • cation binding • transition metal ion binding • iron ion binding • ion binding • metal ion binding • small molecule binding • calcium ion binding • molecular transducer activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • electron transport chain • metabolic process • cellular process • generation of precursor metabolites and energy • response to stimulus • immune response • immune system process • regulation of biological process • signaling • biological regulation • cell-cell signaling • cell communication • cellular response to stimulus • regulation of cellular process
Gene Ontology	Biological Process	• electron transport chain • metabolic process • cellular process • generation of precursor metabolites and energy • response to stimulus • immune response • immune system process • regulation of biological process • signaling • biological regulation • cell-cell signaling • cell communication • cellular response to stimulus • regulation of cellular process • adenylate cyclase-activating G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • signal transduction • cell surface receptor signaling pathway • cell adhesion • defense response • response to stress • inflammatory response • cellular anatomical structure • periplasmic space • anchoring junction • cell junction • focal adhesion • cell-substrate junction • membrane • extracellular exosome • membrane-bounded organelle • extracellular vesicle • extracellular organelle • extracellular region • organelle • extracellular space
Gene Ontology	Cellular Component	• cellular anatomical structure • periplasmic space • anchoring junction • cell junction • focal adhesion • cell-substrate junction • membrane • extracellular exosome • membrane-bounded organelle • extracellular vesicle • extracellular organelle • extracellular region • organelle • extracellular space • vesicle • extracellular membrane-bounded organelle • cell periphery • plasma membrane • intracellular anatomical structure • intracellular vesicle • intracellular membrane-bounded organelle • endomembrane system • intracellular organelle • cytoplasmic vesicle membrane • bounding membrane of organelle • vesicle membrane • cytoplasmic vesicle • secretory granule • secretory vesicle • cytoplasm • organelle membrane • secretory granule membrane
SCOP2	Domain Identifier
SCOP2	Family Identifier
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	NAG
PDB Residues	H:H:?1 H:H:?2 H:H:?3
Environment Details	Open EMBL-EBI Page
Code	NAG
Name	N-Acetylglucosamine
Synonyms	N-Acetylglucosamine
Identifier
Formula	C8 H15 N O6
Molecular Weight	221.208
SMILES
PubChem	24139
Formal Charge	0
Total Atoms	30
Total Chiral Atoms	5
Total Bonds	30
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P48960
Sequence	>8IKJ_Chain_R D M T F S T W T P P P G V H S Q T L S R F F D K V Q D L G R D S K T S S A E V T I Q N V I K L V D E L M E A P G D V E A L A P P V R H L I A T Q L L S N L E D I M R I L A K S L P K G P F T Y I S P S N T E L T L M I Q E R G D K N V T M G Q S S A R M K L N W A V A A G A E D P G P A V A G I L S I Q N M T T L L A N A S L N L H S K K Q A E L E E I Y E S S I R G V Q L R R L S A V N S I F L S H N N T K E L N S P I L F A F S H L E S S D G E A G R D P P A K D V M P G P R Q E L L C A F W K S D S D R G G H W A T E G C Q V L G S K N G S T T C Q C S S L S S F A I L M A H Y D V E D W K L T L I T R V G L A L S L F C L L L C I L T F L L V R P I Q G S R T T I H L H L C I C L F V G S T I F L A G I E N E G G Q V G L R C R L V A G L L H Y C F L A A F C W M S L E G L E L Y F L V V R V F Q G Q G L S T R W L C L I G Y G V P L L I V G V S A A I Y S K G Y G R P R Y C W L D F E Q G F L W S F L G P V T F I I L C N A V I F V T T V W K L T Q K A R A L T I T A I A Q L F L L G C T W V F G L F I F D D R S L V L T Y V F T I L N C L Q G A F L Y L L H C L L N K K V R E E Y R K W A C Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	7YDH	B2	Adhesion	Adhesion	ADGRE5	Homo sapiens	-	-	chim(NtGi2-G13)/β1/γ2	3.1	2023-07-12	doi.org/10.1016/j.chembiol.2023.08.003
	7YDH (No Gprot)	B2	Adhesion	Adhesion	ADGRE5	Homo sapiens	-	-		3.1	2023-07-12	doi.org/10.1016/j.chembiol.2023.08.003
	7YDM	B2	Adhesion	Adhesion	ADGRE5	Homo sapiens	-	-	chim(NtGi1-Gs-CtGq)/β1/γ2	2.89	2023-07-12	doi.org/10.1016/j.chembiol.2023.08.003
	7YDM (No Gprot)	B2	Adhesion	Adhesion	ADGRE5	Homo sapiens	-	-		2.89	2023-07-12	doi.org/10.1016/j.chembiol.2023.08.003
	7YDP	B2	Adhesion	Adhesion	ADGRE5	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	3.1	2023-07-12	doi.org/10.1016/j.chembiol.2023.08.003
	7YDP (No Gprot)	B2	Adhesion	Adhesion	ADGRE5	Homo sapiens	-	-		3.1	2023-07-12	doi.org/10.1016/j.chembiol.2023.08.003
	8IKL	B2	Adhesion	Adhesion	ADGRE5	Homo sapiens	-	-	chim(NtGi1L-G13)/β1/γ2	2.33	2024-01-24	doi.org/10.1016/j.molcel.2023.12.020
	8IKL (No Gprot)	B2	Adhesion	Adhesion	ADGRE5	Homo sapiens	-	-		2.33	2024-01-24	doi.org/10.1016/j.molcel.2023.12.020
	8IKJ	B2	Adhesion	Adhesion	ADGRE5	Homo sapiens	-	-	-	3.2	2024-02-14	doi.org/10.1016/j.molcel.2023.12.020
	7YDJ	B2	Adhesion	Adhesion	ADGRE5	Homo sapiens	-	-	chim(NtGi1-G12)/β1/γ2	3.03	2023-07-12	To be published
	7YDJ (No Gprot)	B2	Adhesion	Adhesion	ADGRE5	Homo sapiens	-	-		3.03	2023-07-12	To be published

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

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