psnGPCR

Press and hold down the left mouse button and move the mouse to rotate.
Press and hold down the central mouse button and move the mouse to translate.
Use the mouse wheel to zoom in or out.
Click on any atom on your molecule and the corresponding residue label will be placed beneath the viewer.

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:I5	R:R:N260	8.5	No	No	0	4	5
2	R:R:F9	R:R:I263	5.02	No	No	0	4	4
3	R:R:F9	R:R:L264	8.53	No	No	0	4	4
4	R:R:T10	R:R:W66	8.49	No	Yes	0	5	4
5	R:R:F11	R:R:V15	5.24	No	No	0	5	5
6	R:R:L13	R:R:W66	4.56	No	Yes	0	4	4
7	R:R:L13	R:R:M270	4.24	No	Yes	0	4	4
8	R:R:E16	R:R:V267	5.7	Yes	No	0	8	4
9	R:R:E16	R:R:M270	6.77	Yes	Yes	0	8	4
10	R:R:F17	R:R:N21	15.71	No	No	4	5	6
11	R:R:F17	R:R:W60	7.02	No	No	4	5	3
12	R:R:F17	R:R:F63	32.15	No	No	0	5	4
13	R:R:I19	R:R:S274	6.19	No	No	0	5	7
14	R:R:N21	R:R:W60	7.91	No	No	4	6	3
15	R:R:N24	R:R:R55	6.03	Yes	Yes	1	9	9
16	R:R:I56	R:R:N24	7.08	No	Yes	0	6	9
17	R:R:N24	R:R:S277	10.43	Yes	No	1	9	9
18	R:R:F26	R:R:V294	5.24	No	No	0	8	5
19	R:R:A52	R:R:I27	4.87	No	No	0	8	9
20	R:R:I27	R:R:I281	5.89	No	Yes	0	9	9
21	R:R:I27	R:R:L287	7.14	No	No	0	9	9
22	R:R:I33	R:R:L29	5.71	No	No	0	4	5
23	R:R:D45	R:R:N31	4.04	No	No	0	8	8
24	R:R:N31	R:R:T49	5.85	No	No	0	8	6
25	R:R:D34	R:R:R39	8.34	No	No	0	6	6
26	R:R:D34	R:R:K286	11.06	No	No	0	6	8
27	R:R:V36	R:R:W35	4.9	No	No	0	5	5
28	R:R:I41	R:R:W35	4.7	No	No	0	6	5
29	R:R:K37	R:R:R39	7.43	No	No	0	6	6
30	R:R:D45	R:R:I41	5.6	No	No	0	8	6
31	R:R:S42	R:R:V44	4.85	No	No	0	8	6
32	R:R:D45	R:R:S42	8.83	No	No	0	8	8
33	R:R:F106	R:R:S43	6.61	Yes	No	0	7	6
34	R:R:F106	R:R:V44	5.24	Yes	No	0	7	6
35	R:R:I47	R:R:L103	5.71	No	No	0	9	9
36	R:R:L48	R:R:N284	4.12	No	No	0	8	9
37	R:R:L51	R:R:R55	10.93	No	Yes	0	9	9
38	R:R:S54	R:R:S96	6.52	No	No	0	9	7
39	R:R:R55	R:R:S96	3.95	Yes	No	0	9	7
40	R:R:A100	R:R:R55	4.15	No	Yes	0	8	9
41	R:R:R55	R:R:Y272	7.2	Yes	Yes	1	9	5
42	R:R:P273	R:R:R55	4.32	No	Yes	0	8	9
43	R:R:H276	R:R:R55	11.28	Yes	Yes	1	9	9
44	R:R:R55	R:R:S277	6.59	Yes	No	1	9	9
45	R:R:I56	R:R:W60	4.7	No	No	0	6	3
46	R:R:I92	R:R:S57	4.64	No	No	0	4	3
47	R:R:L58	R:R:W89	4.56	No	Yes	6	4	4
48	R:R:I92	R:R:L58	7.14	No	No	0	4	4
49	R:R:L58	R:R:N93	10.98	No	Yes	6	4	8
50	R:R:M270	R:R:V59	9.13	Yes	No	0	4	7
51	R:R:I62	R:R:W89	4.7	No	Yes	0	4	4
52	R:R:I62	R:R:M270	8.75	No	Yes	0	4	4
53	R:R:F63	R:R:W66	9.02	No	Yes	0	4	4
54	R:R:Q266	R:R:S65	5.78	No	No	0	3	4
55	R:R:V70	R:R:W66	4.9	No	Yes	3	4	4
56	R:R:F71	R:R:W66	8.02	No	Yes	3	4	4
57	R:R:Q266	R:R:W66	4.38	No	Yes	0	3	4
58	R:R:C67	R:R:F71	8.38	No	No	0	4	4
59	R:R:F76	R:R:V68	5.24	No	No	0	3	3
60	R:R:F76	R:R:S69	13.21	No	No	0	3	4
61	R:R:F71	R:R:V70	9.18	No	No	3	4	4
62	R:R:A74	R:R:F72	4.16	No	No	0	2	4
63	R:R:F72	R:R:L75	6.09	No	No	0	4	2
64	R:R:L75	R:R:T78	7.37	No	No	0	2	4
65	R:R:L75	R:R:M81	8.48	No	No	0	2	3
66	L:L:?3	R:R:F76	13.36	Yes	No	0	0	3
67	R:R:E79	R:R:K80	5.4	No	No	0	2	3
68	R:R:E79	R:R:I156	10.93	No	No	0	2	3
69	R:R:L85	R:R:M81	5.65	No	No	0	2	3
70	R:R:F82	R:R:I152	5.02	No	Yes	2	2	3
71	R:R:F175	R:R:F82	7.5	Yes	No	2	2	2
72	L:L:?3	R:R:F82	19.43	Yes	No	0	0	2
73	R:R:N149	R:R:R83	7.23	No	No	2	4	3
74	R:R:I152	R:R:R83	13.78	Yes	No	2	3	3
75	R:R:N153	R:R:R83	8.44	No	No	0	3	3
76	L:L:?3	R:R:L85	5.52	Yes	No	0	0	2
77	L:L:?3	R:R:T86	5.88	Yes	No	0	0	3
78	R:R:N149	R:R:N87	8.17	No	No	0	4	4
79	R:R:N93	R:R:W89	19.21	Yes	Yes	6	8	4
80	L:L:?3	R:R:W89	37.48	Yes	Yes	0	0	4
81	R:R:I145	R:R:T90	4.56	No	No	0	6	5
82	R:R:N93	R:R:V97	4.43	Yes	No	0	8	5
83	R:R:I187	R:R:N93	5.66	No	Yes	0	5	8
84	R:R:H94	R:R:W98	15.87	No	Yes	0	5	9
85	R:R:H94	R:R:L141	15.43	No	No	0	5	8
86	R:R:T101	R:R:W98	6.06	No	Yes	0	8	9
87	R:R:L133	R:R:W98	5.69	No	Yes	0	7	9
88	R:R:T137	R:R:W98	27.9	No	Yes	0	8	9
89	R:R:P190	R:R:W98	21.62	No	Yes	0	9	9
90	R:R:L193	R:R:T101	4.42	No	No	0	5	8
91	R:R:L103	R:R:Y107	10.55	No	No	0	9	9
92	R:R:G104	W:W:?1	6.38	No	Yes	0	8	0
93	R:R:M197	R:R:T105	4.52	No	No	0	8	7
94	R:R:F106	R:R:Y107	4.13	Yes	No	0	7	9
95	R:R:F106	R:R:K110	11.17	Yes	No	5	7	9
96	R:R:F106	R:R:V126	5.24	Yes	No	5	7	7
97	R:R:Y107	W:W:?1	14.57	No	Yes	0	9	0
98	R:R:F108	R:R:F114	5.36	No	Yes	1	8	8
99	R:R:F108	R:R:F119	6.43	No	Yes	1	8	9
100	R:R:F108	R:R:L200	6.09	No	No	0	8	7
101	R:R:L109	R:R:V129	4.47	No	No	0	7	6
102	R:R:K110	R:R:V126	6.07	No	No	5	9	7
103	R:R:I111	R:R:L201	4.28	No	Yes	1	9	9
104	R:R:I111	W:W:?2	4.44	No	Yes	1	9	0
105	R:R:A112	R:R:F119	4.16	No	Yes	0	8	9
106	R:R:F114	R:R:F119	11.79	Yes	Yes	1	8	9
107	R:R:F114	R:R:F203	4.29	Yes	No	0	8	5
108	R:R:F114	R:R:S204	3.96	Yes	No	1	8	9
109	R:R:F119	R:R:K123	6.2	Yes	No	0	9	9
110	R:R:L122	R:R:Y121	4.69	No	No	0	8	5
111	R:R:R125	R:R:Y121	12.35	No	No	0	8	5
112	R:R:L122	R:R:V129	4.47	No	No	0	8	6
113	R:R:K128	R:R:R125	9.9	No	No	0	6	8
114	R:R:F140	R:R:F186	4.29	No	No	0	3	4
115	R:R:L143	R:R:L147	5.54	No	No	0	3	4
116	R:R:F186	R:R:L143	4.87	No	No	0	4	3
117	R:R:F186	R:R:N144	26.58	No	No	0	4	5
118	R:R:I152	R:R:N149	5.66	Yes	No	2	3	4
119	R:R:H151	R:R:L178	7.71	Yes	No	0	2	3
120	R:R:H151	R:R:I179	3.98	Yes	No	0	2	3
121	R:R:H151	R:R:T182	4.11	Yes	No	0	2	6
122	R:R:F175	R:R:I152	5.02	Yes	Yes	2	2	3
123	R:R:F175	R:R:S155	18.5	Yes	No	0	2	3
124	R:R:F172	R:R:F175	5.36	No	Yes	0	3	2
125	R:R:F172	R:R:S176	5.28	No	No	0	3	4
126	R:R:L257	R:R:T173	11.79	No	No	0	1	3
127	R:R:F175	R:R:I179	6.28	Yes	No	0	2	3
128	R:R:V180	R:R:V251	6.41	No	Yes	0	3	3
129	L:L:?3	R:R:V180	7.43	Yes	No	0	0	3
130	R:R:F248	R:R:L181	12.18	No	No	0	4	2
131	R:R:L181	R:R:V251	7.45	No	Yes	0	2	3
132	R:R:L181	R:R:W252	6.83	No	No	0	2	3
133	R:R:F248	R:R:T184	6.49	No	No	0	4	5
134	L:L:?3	R:R:T184	13.23	Yes	No	0	0	5
135	L:L:?3	R:R:I187	4.27	Yes	No	0	0	5
136	R:R:F188	R:R:S244	9.25	No	No	0	3	5
137	R:R:F191	R:R:F237	7.5	No	Yes	0	7	6
138	R:R:F191	R:R:Y240	5.16	No	Yes	0	7	8
139	R:R:L193	R:R:M197	4.24	No	No	0	5	8
140	R:R:F237	R:R:S194	5.28	Yes	No	1	6	8
141	R:R:S194	W:W:?1	4.67	No	Yes	1	8	0
142	R:R:F237	R:R:L195	10.96	Yes	No	0	6	7
143	R:R:F198	R:R:I202	10.05	Yes	No	0	7	8
144	R:R:F198	R:R:V233	7.87	Yes	No	1	7	7
145	R:R:F198	R:R:I234	6.28	Yes	No	0	7	5
146	R:R:F198	W:W:?1	20.44	Yes	Yes	1	7	0
147	R:R:L201	R:R:S204	4.5	Yes	No	1	9	9
148	R:R:L201	W:W:?1	9.46	Yes	Yes	1	9	0
149	R:R:L201	W:W:?2	5.16	Yes	Yes	1	9	0
150	R:R:F203	R:R:W206	5.01	No	No	0	5	4
151	R:R:S204	W:W:?2	6.53	No	Yes	1	9	0
152	R:R:M205	W:W:?2	19.33	No	Yes	0	9	0
153	R:R:H208	R:R:K211	5.24	No	No	0	9	5
154	R:R:H208	R:R:M212	9.19	No	No	0	9	9
155	R:R:H208	W:W:?2	11.19	No	Yes	0	9	0
156	R:R:H227	R:R:R209	10.16	No	No	0	9	6
157	R:R:R209	W:W:?2	4.53	No	Yes	0	6	0
158	R:R:K217	R:R:M212	5.76	No	No	0	5	9
159	R:R:H227	R:R:S223	6.97	No	No	0	9	8
160	R:R:L282	R:R:S232	4.5	No	No	0	6	7
161	R:R:V233	W:W:?1	16.67	No	Yes	1	7	0
162	R:R:F236	R:R:Y240	5.16	Yes	Yes	1	9	8
163	R:R:F236	R:R:Y272	5.16	Yes	Yes	1	9	5
164	R:R:F236	R:R:H276	13.58	Yes	Yes	1	9	9
165	R:R:F236	R:R:V279	5.24	Yes	No	0	9	7
166	R:R:F237	W:W:?1	5.3	Yes	Yes	1	6	0
167	R:R:M268	R:R:Y240	4.79	No	Yes	0	5	8
168	R:R:Y240	R:R:Y272	15.89	Yes	Yes	1	8	5
169	L:L:?3	R:R:S244	4.49	Yes	No	0	0	5
170	R:R:F247	R:R:V251	5.24	No	Yes	0	3	3
171	R:R:F247	R:R:L264	8.53	No	No	0	3	4
172	R:R:F247	R:R:M268	11.2	No	No	0	3	5
173	R:R:E258	R:R:S250	10.06	Yes	No	0	4	3
174	R:R:E258	R:R:S254	5.75	Yes	No	0	4	2
175	R:R:I263	R:R:N260	5.66	No	No	0	4	5
176	L:L:?3	R:R:I262	4.27	Yes	No	0	0	1
177	L:L:?3	R:R:S265	13.48	Yes	No	0	0	4
178	L:L:?3	R:R:M268	8.46	Yes	No	0	0	5
179	L:L:?3	R:R:G269	5.12	Yes	No	0	0	4
180	R:R:H276	R:R:Y272	16.33	Yes	Yes	1	9	5
181	R:R:H276	R:R:L280	6.43	Yes	No	0	9	9
182	R:R:H276	W:W:?1	12.79	Yes	Yes	1	9	0
183	R:R:L287	R:R:N284	9.61	No	No	0	9	9
184	R:R:K285	R:R:R288	6.19	No	No	0	6	8
185	R:R:Q289	R:R:R288	4.67	No	No	0	7	8
186	R:R:L292	R:R:Q289	3.99	No	No	0	5	7
187	R:R:L296	R:R:R299	4.86	No	No	0	3	7
188	R:R:L298	R:R:W297	4.56	No	No	0	5	3
189	R:R:F26	R:R:V30	3.93	No	No	0	8	8
190	R:R:C32	R:R:W35	3.92	No	No	0	4	5
191	R:R:A226	W:W:?2	3.92	No	Yes	0	8	0
192	R:R:H151	R:R:L147	3.86	Yes	No	0	2	4
193	R:R:F26	R:R:I281	3.77	No	Yes	0	8	9
194	R:R:F203	R:R:K207	3.72	No	No	0	5	7
195	R:R:S183	R:R:W89	3.71	No	Yes	0	7	4
196	R:R:G220	R:R:S219	3.71	No	No	0	6	5
197	R:R:F188	R:R:L245	3.65	No	No	0	3	4
198	R:R:T90	R:R:W89	3.64	No	Yes	0	5	4
199	R:R:P190	R:R:V97	3.53	No	No	0	9	5
200	R:R:C275	R:R:S274	3.44	No	No	0	4	7
201	R:R:A290	R:R:V30	3.39	No	No	0	5	8
202	R:R:I189	R:R:P190	3.39	No	No	0	6	9
203	R:R:S219	R:R:S223	3.26	No	No	0	5	8
204	R:R:S177	R:R:V251	3.23	No	Yes	0	3	3
205	R:R:S232	R:R:V279	3.23	No	No	0	7	7
206	R:R:A50	R:R:L99	3.15	No	Yes	0	6	5
207	R:R:A52	R:R:N24	3.13	No	Yes	0	8	9
208	R:R:I148	R:R:S183	3.1	No	No	0	4	7
209	R:R:I156	R:R:S155	3.1	No	No	0	3	3
210	R:R:I202	R:R:V230	3.07	No	No	0	8	7
211	R:R:I234	R:R:V230	3.07	No	No	0	5	7
212	R:R:K127	R:R:V130	3.04	No	No	0	7	7
213	R:R:K128	R:R:V132	3.04	No	No	0	6	3
214	R:R:I249	R:R:T253	3.04	No	No	0	4	4
215	R:R:A271	R:R:E16	3.02	No	Yes	0	6	8
216	R:R:M212	R:R:T215	3.01	No	No	0	9	6
217	R:R:L261	R:R:S177	3	No	No	0	1	3
218	R:R:L109	R:R:V126	2.98	No	No	0	7	7
219	R:R:L298	R:R:V294	2.98	No	No	0	5	5
220	R:R:I88	R:R:I92	2.94	No	No	0	3	4
221	R:R:I263	R:R:K6	2.91	No	No	0	4	4
222	R:R:I47	R:R:K127	2.91	No	No	0	9	7
223	R:R:I218	R:R:K217	2.91	No	No	0	6	5
224	R:R:E16	R:R:V12	2.85	Yes	No	0	8	6
225	R:R:I88	R:R:L61	2.85	No	No	0	3	4
226	R:R:I118	R:R:L122	2.85	No	No	0	4	8
227	R:R:K123	R:R:L120	2.82	No	No	0	9	7
228	R:R:K286	R:R:N31	2.8	No	No	0	8	8
229	R:R:C275	R:R:F236	2.79	No	Yes	0	4	9
230	R:R:L51	R:R:L99	2.77	No	Yes	0	9	5
231	R:R:A241	R:R:F191	2.77	No	No	0	6	7
232	R:R:L195	R:R:L199	2.77	No	No	0	7	4
233	R:R:H214	R:R:T215	2.74	No	No	0	5	6
234	R:R:E258	R:R:L264	2.65	Yes	No	0	4	4
235	R:R:F142	R:R:S138	2.64	No	No	0	3	6
236	R:R:F248	R:R:V185	2.62	No	No	0	4	6
237	R:R:F63	R:R:I14	2.51	No	No	0	4	4
238	R:R:I41	R:R:R46	2.51	No	No	0	6	5
239	R:R:F243	R:R:I242	2.51	No	No	0	7	5
240	R:R:K231	R:R:R228	2.48	No	No	0	7	5
241	R:R:F95	R:R:L99	2.44	No	Yes	0	6	5
242	R:R:T253	R:R:W252	2.43	No	No	0	4	3
243	R:R:K210	R:R:W206	2.32	No	No	0	6	4
244	R:R:G2	R:R:G3	2.11	No	No	0	4	4
245	R:R:C67	R:R:G64	1.96	No	No	0	4	3
246	R:R:G20	R:R:S274	1.86	No	No	0	9	7
247	R:R:G229	R:R:S232	1.86	No	No	0	9	7
248	R:R:G102	R:R:V130	1.84	No	No	0	5	7
249	R:R:G2	R:R:I5	1.76	No	No	0	4	4
250	R:R:G23	R:R:I281	1.76	No	Yes	0	7	9
251	R:R:G23	R:R:L22	1.71	No	No	0	7	4
252	R:R:G158	R:R:N157	1.7	No	No	0	2	1
253	R:R:D221	R:R:G220	1.68	No	No	0	8	6
254	R:R:A28	R:R:I53	1.62	No	No	0	7	6
255	R:R:V132	R:R:V136	1.6	No	No	0	3	6
256	R:R:I8	R:R:S7	1.55	No	No	0	6	3
257	R:R:I281	R:R:S291	1.55	Yes	No	0	9	5
258	R:R:I8	R:R:V12	1.54	No	No	0	6	6
259	R:R:I19	R:R:V15	1.54	No	No	0	5	5
260	R:R:I145	R:R:V91	1.54	No	No	0	6	6
261	R:R:K40	R:R:S42	1.53	No	No	0	6	8
262	R:R:G229	R:R:R228	1.5	No	No	0	9	5
263	R:R:L295	R:R:S291	1.5	No	No	0	7	5
264	R:R:N116	R:R:S115	1.49	No	No	0	8	8
265	R:R:I53	R:R:I56	1.47	No	No	0	6	6
266	R:R:I88	R:R:M84	1.46	No	No	0	3	3
267	R:R:I33	R:R:K37	1.45	No	No	0	4	6
268	R:R:F72	R:R:P73	1.44	No	No	0	4	4
269	R:R:I18	R:R:L22	1.43	No	No	0	6	4
270	R:R:I234	R:R:L238	1.43	No	No	0	5	5
271	R:R:I242	R:R:L239	1.43	No	No	0	5	7
272	R:R:I156	R:R:N157	1.42	No	No	0	3	1
273	R:R:L134	R:R:L99	1.38	No	Yes	0	8	5
274	R:R:H151	R:R:I150	1.33	Yes	No	0	2	3
275	R:R:K225	R:R:R288	1.24	No	No	0	6	8
276	R:R:F142	R:R:L141	1.22	No	No	0	3	8
277	R:R:F119	R:R:N116	1.21	Yes	No	0	9	8
278	R:R:L257	R:R:R174	1.21	No	No	0	1	2
279	R:R:E258	R:R:R256	1.16	Yes	No	0	4	1
280	R:R:G283	W:W:?1	1.06	No	Yes	0	7	0
281	R:R:N113	W:W:?2	0.85	No	Yes	0	8	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:E16	4.585	4	0	8
2	R:R:N24	6.6675	4	1	9
3	R:R:R55	6.80625	8	1	9
4	R:R:W66	6.56167	6	3	4
5	R:R:W89	12.2167	6	6	4
6	R:R:N93	10.07	4	6	8
7	R:R:W98	15.428	5	0	9
8	R:R:L99	2.435	4	0	5
9	R:R:F106	6.478	5	5	7
10	R:R:F114	6.35	4	1	8
11	R:R:F119	5.958	5	1	9
12	R:R:H151	4.198	5	0	2
13	R:R:I152	7.37	4	2	3
14	R:R:F175	8.532	5	2	2
15	R:R:F198	11.16	4	1	7
16	R:R:L201	5.85	4	1	9
17	R:R:F236	6.386	5	1	9
18	R:R:F237	7.26	4	1	6
19	R:R:Y240	7.75	4	1	8
20	R:R:V251	5.5825	4	0	3
21	R:R:E258	4.905	4	0	4
22	R:R:M270	7.2225	4	0	4
23	R:R:Y272	11.145	4	1	5
24	R:R:H276	12.082	5	1	9
25	R:R:I281	3.2425	4	0	9
26	W:W:?1	10.1489	9	1	0
27	W:W:?2	6.99375	8	1	0
28	L:L:?3	10.9554	13	0	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:F247	R:R:L264	14.2214	8.53	No	No	0	3	4
2	R:R:F247	R:R:M268	20.9432	11.2	No	No	0	3	5
3	L:L:?3	R:R:M268	86.5251	8.46	Yes	No	0	0	5
4	L:L:?3	R:R:W89	40.1282	37.48	Yes	Yes	0	0	4
5	R:R:I62	R:R:W89	14.3126	4.7	No	Yes	0	4	4
6	R:R:I62	R:R:M270	13.435	8.75	No	Yes	0	4	4
7	R:R:F236	R:R:Y240	32.6884	5.16	Yes	Yes	1	9	8
8	R:R:M268	R:R:Y240	100	4.79	No	Yes	0	5	8
9	R:R:N24	R:R:R55	19.1452	6.03	Yes	Yes	1	9	9
10	R:R:R55	R:R:Y272	12.8565	7.2	Yes	Yes	1	9	5
11	R:R:Y240	R:R:Y272	39.1224	15.89	Yes	Yes	1	8	5
12	R:R:A52	R:R:I27	11.7795	4.87	No	No	0	8	9
13	R:R:A52	R:R:N24	12.4861	3.13	No	Yes	0	8	9
14	R:R:D45	R:R:N31	11.3549	4.04	No	No	0	8	8
15	R:R:D45	R:R:S42	19.7493	8.83	No	No	0	8	8
16	R:R:S42	R:R:V44	22.5018	4.85	No	No	0	8	6
17	R:R:F106	R:R:V44	23.7213	5.24	Yes	No	0	7	6
18	R:R:F106	R:R:Y107	40.8349	4.13	Yes	No	0	7	9
19	R:R:Y107	W:W:?1	48.326	14.57	No	Yes	0	9	0
20	R:R:F237	W:W:?1	28.5995	5.3	Yes	Yes	1	6	0
21	R:R:F191	R:R:F237	29.0041	7.5	No	Yes	0	7	6
22	R:R:F191	R:R:Y240	29.574	5.16	No	Yes	0	7	8
23	R:R:H276	W:W:?1	68.4513	12.79	Yes	Yes	1	9	0
24	R:R:F236	R:R:H276	32.5032	13.58	Yes	Yes	1	9	9
25	R:R:H276	R:R:Y272	27.9271	16.33	Yes	Yes	1	9	5
26	R:R:N93	R:R:W89	16.9597	19.21	Yes	Yes	6	8	4
27	L:L:?3	R:R:I187	16.7203	4.27	Yes	No	0	0	5
28	R:R:I187	R:R:N93	15.78	5.66	No	Yes	0	5	8
29	R:R:F175	R:R:F82	21.9746	7.5	Yes	No	2	2	2
30	L:L:?3	R:R:F82	28.7249	19.43	Yes	No	0	0	2
31	R:R:N93	R:R:V97	30.6739	4.43	Yes	No	0	8	5
32	R:R:P190	R:R:W98	24.1943	21.62	No	Yes	0	9	9
33	R:R:P190	R:R:V97	28.5197	3.53	No	No	0	9	5
34	R:R:F106	R:R:V126	14.3012	5.24	Yes	No	5	7	7
35	R:R:F114	R:R:S204	18.3644	3.96	Yes	No	1	8	9
36	R:R:L201	R:R:S204	19.0768	4.5	Yes	No	1	9	9
37	R:R:L201	W:W:?1	43.9806	9.46	Yes	Yes	1	9	0
38	R:R:L109	R:R:V126	12.9221	2.98	No	No	0	7	7
39	R:R:L109	R:R:V129	11.5059	4.47	No	No	0	7	6
40	R:R:L201	W:W:?2	22.4106	5.16	Yes	Yes	1	9	0
41	R:R:L122	R:R:V129	10.0869	4.47	No	No	0	8	6
42	R:R:H151	R:R:I179	10.8705	3.98	Yes	No	0	2	3
43	R:R:F175	R:R:I179	12.0501	6.28	Yes	No	0	2	3
44	R:R:H276	R:R:R55	12.6542	11.28	Yes	Yes	1	9	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:L58	R:R:W89	4.56	6	No	Yes	4	4	2	1
R:R:L58	R:R:N93	10.98	6	No	Yes	4	8	2	2
R:R:I62	R:R:W89	4.7	0	No	Yes	4	4	2	1
R:R:F76	R:R:V68	5.24	0	No	No	3	3	1	2
R:R:F76	R:R:S69	13.21	0	No	No	3	4	1	2
L:L:?3	R:R:F76	13.36	0	Yes	No	0	3	0	1
R:R:L85	R:R:M81	5.65	0	No	No	2	3	1	2
R:R:F82	R:R:I152	5.02	2	No	Yes	2	3	1	2
R:R:F175	R:R:F82	7.5	2	Yes	No	2	2	2	1
L:L:?3	R:R:F82	19.43	0	Yes	No	0	2	0	1
L:L:?3	R:R:L85	5.52	0	Yes	No	0	2	0	1
L:L:?3	R:R:T86	5.88	0	Yes	No	0	3	0	1
R:R:N93	R:R:W89	19.21	6	Yes	Yes	8	4	2	1
L:L:?3	R:R:W89	37.48	0	Yes	Yes	0	4	0	1
R:R:I187	R:R:N93	5.66	0	No	Yes	5	8	1	2
R:R:F175	R:R:I152	5.02	2	Yes	Yes	2	3	2	2
R:R:V180	R:R:V251	6.41	0	No	Yes	3	3	1	2
L:L:?3	R:R:V180	7.43	0	Yes	No	0	3	0	1
R:R:F248	R:R:T184	6.49	0	No	No	4	5	2	1
L:L:?3	R:R:T184	13.23	0	Yes	No	0	5	0	1
L:L:?3	R:R:I187	4.27	0	Yes	No	0	5	0	1
R:R:F188	R:R:S244	9.25	0	No	No	3	5	2	1
R:R:M268	R:R:Y240	4.79	0	No	Yes	5	8	1	2
L:L:?3	R:R:S244	4.49	0	Yes	No	0	5	0	1
R:R:F247	R:R:V251	5.24	0	No	Yes	3	3	2	2
R:R:F247	R:R:M268	11.2	0	No	No	3	5	2	1
L:L:?3	R:R:I262	4.27	0	Yes	No	0	1	0	1
L:L:?3	R:R:S265	13.48	0	Yes	No	0	4	0	1
L:L:?3	R:R:M268	8.46	0	Yes	No	0	5	0	1
L:L:?3	R:R:G269	5.12	0	Yes	No	0	4	0	1
R:R:S183	R:R:W89	3.71	0	No	Yes	7	4	2	1
R:R:T90	R:R:W89	3.64	0	No	Yes	5	4	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:I111	R:R:L201	4.28	1	No	Yes	9	9	1	1
R:R:I111	W:W:?2	4.44	1	No	Yes	9	0	1	0
R:R:F114	R:R:S204	3.96	1	Yes	No	8	9	2	1
R:R:L201	R:R:S204	4.5	1	Yes	No	9	9	1	1
R:R:L201	W:W:?1	9.46	1	Yes	Yes	9	0	1	2
R:R:L201	W:W:?2	5.16	1	Yes	Yes	9	0	1	0
R:R:S204	W:W:?2	6.53	1	No	Yes	9	0	1	0
R:R:M205	W:W:?2	19.33	0	No	Yes	9	0	1	0
R:R:H208	R:R:K211	5.24	0	No	No	9	5	1	2
R:R:H208	R:R:M212	9.19	0	No	No	9	9	1	2
R:R:H208	W:W:?2	11.19	0	No	Yes	9	0	1	0
R:R:H227	R:R:R209	10.16	0	No	No	9	6	2	1
R:R:R209	W:W:?2	4.53	0	No	Yes	6	0	1	0
R:R:A226	W:W:?2	3.92	0	No	Yes	8	0	1	0
R:R:N113	W:W:?2	0.85	0	No	Yes	8	0	1	0

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:R55	R:R:Y272	7.2	1	Yes	Yes	9	5	2	2
R:R:H276	R:R:R55	11.28	1	Yes	Yes	9	9	1	2
R:R:L103	R:R:Y107	10.55	0	No	No	9	9	2	1
R:R:G104	W:W:?1	6.38	0	No	Yes	8	0	1	0
R:R:F106	R:R:Y107	4.13	5	Yes	No	7	9	2	1
R:R:Y107	W:W:?1	14.57	0	No	Yes	9	0	1	0
R:R:I111	R:R:L201	4.28	1	No	Yes	9	9	2	1
R:R:I111	W:W:?2	4.44	1	No	Yes	9	0	2	2
R:R:F191	R:R:F237	7.5	0	No	Yes	7	6	2	1
R:R:F237	R:R:S194	5.28	1	Yes	No	6	8	1	1
R:R:S194	W:W:?1	4.67	1	No	Yes	8	0	1	0
R:R:F237	R:R:L195	10.96	1	Yes	No	6	7	1	2
R:R:F198	R:R:I202	10.05	1	Yes	No	7	8	1	2
R:R:F198	R:R:V233	7.87	1	Yes	No	7	7	1	1
R:R:F198	R:R:I234	6.28	1	Yes	No	7	5	1	2
R:R:F198	W:W:?1	20.44	1	Yes	Yes	7	0	1	0
R:R:L201	R:R:S204	4.5	1	Yes	No	9	9	1	2
R:R:L201	W:W:?1	9.46	1	Yes	Yes	9	0	1	0
R:R:L201	W:W:?2	5.16	1	Yes	Yes	9	0	1	2
R:R:S204	W:W:?2	6.53	1	No	Yes	9	0	2	2
R:R:V233	W:W:?1	16.67	1	No	Yes	7	0	1	0
R:R:F236	R:R:Y272	5.16	1	Yes	Yes	9	5	2	2
R:R:F236	R:R:H276	13.58	1	Yes	Yes	9	9	2	1
R:R:F237	W:W:?1	5.3	1	Yes	Yes	6	0	1	0
R:R:H276	R:R:Y272	16.33	1	Yes	Yes	9	5	1	2
R:R:H276	R:R:L280	6.43	1	Yes	No	9	9	1	2
R:R:H276	W:W:?1	12.79	1	Yes	Yes	9	0	1	0
R:R:G283	W:W:?1	1.06	0	No	Yes	7	0	1	0

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	8XQL_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.95
Number of Linked Nodes	265
Number of Links	281
Number of Hubs	28
Number of Links mediated by Hubs	127
Number of Communities	6
Number of Nodes involved in Communities	36
Number of Links involved in Communities	45

Path Summary
Number Of Nodes in MetaPath	45
Number Of Links MetaPath	44
Number of Shortest Paths	54644
Length Of Smallest Path	3
Average Path Length	12.6543
Length of Longest Path	27
Minimum Path Strength	1.35
Average Path Strength	8.4988
Maximum Path Strength	28.345
Minimum Path Correlation	0.7
Average Path Correlation	0.927372
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	5.26316
Average % Of Corr. Nodes	47.1583
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	44.6981
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• binding • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • D1 dopamine receptor binding • protein binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • molecular function regulator activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • enzyme regulator activity • molecular function activator activity • phosphorus-oxygen lyase activity • cyclase regulator activity • enzyme activator activity • cyclase activator activity • cyclase activity • adenylate cyclase regulator activity • lyase activity • adenylate cyclase activator activity • adenylate cyclase activity • cation binding • metal ion binding • developmental process • multicellular organismal process • epithelium development • ectodermal placode morphogenesis • epidermis development • molting cycle process • hair cycle • animal organ development • hair follicle placode formation • tissue development • ectodermal placode formation • anatomical structure morphogenesis • skin development • skin epidermis development • hair follicle development
Gene Ontology	Biological Process	• developmental process • multicellular organismal process • epithelium development • ectodermal placode morphogenesis • epidermis development • molting cycle process • hair cycle • animal organ development • hair follicle placode formation • tissue development • ectodermal placode formation • anatomical structure morphogenesis • skin development • skin epidermis development • hair follicle development • molting cycle • anatomical structure development • anatomical structure formation involved in morphogenesis • ectodermal placode development • hair cycle process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of smell • cellular response to stimulus • cellular response to nitrogen compound • response to stimulus • response to endogenous stimulus • response to peptide hormone • cellular response to peptide hormone stimulus • response to oxygen-containing compound • response to nitrogen compound • response to glucagon • cellular response to oxygen-containing compound • cellular response to glucagon stimulus • cellular response to endogenous stimulus • cellular response to chemical stimulus • response to hormone • response to chemical • cellular process • cellular response to hormone stimulus • multicellular organism development • skeletal system development • bone development • system development • regulation of body fluid levels • wound healing • homotypic cell-cell adhesion • cell activation • hemostasis • biological regulation • platelet aggregation • blood coagulation • cell adhesion • cell-cell adhesion • response to stress • coagulation • regulation of biological quality • response to wounding • platelet activation • response to fluid shear stress • vascular endothelial cell response to laminar fluid shear stress • response to laminar fluid shear stress • cellular response to stress • cellular response to laminar fluid shear stress • vascular endothelial cell response to fluid shear stress • cellular response to fluid shear stress • cognition • developmental growth • growth • response to ketone • response to prostaglandin • response to lipid • response to alcohol • cellular response to prostaglandin stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • cellular response to lipid • response to prostaglandin E • cellular response to ketone • regulation of biological process • regulation of cellular process • signaling • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cell communication • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • signal transduction • homeostatic process • positive regulation of biological process • adaptive thermogenesis • positive regulation of metabolic process • multicellular organismal-level homeostasis • regulation of cold-induced thermogenesis • cold-induced thermogenesis • temperature homeostasis • positive regulation of cold-induced thermogenesis • positive regulation of multicellular organismal process • metabolic process • regulation of multicellular organismal process • regulation of metabolic process • positive regulation of cellular process • protein localization • regulation of localization • establishment of protein localization • nitrogen compound transport • localization • cellular macromolecule localization • regulation of peptide hormone secretion • regulation of hormone levels • establishment of protein localization to extracellular region • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • cellular localization • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • transport • hormone secretion • protein localization to extracellular region • peptide secretion • regulation of secretion by cell • secretion by cell • amide transport • signal release • regulation of signaling • regulation of transport • secretion • regulation of peptide transport • regulation of establishment of protein localization • export from cell • cell-cell signaling • regulation of protein transport • peptide transport • protein transport • regulation of cellular localization • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • hormone transport • regulation of cell communication • insulin secretion • adenylate cyclase-activating adrenergic receptor signaling pathway • adrenergic receptor signaling pathway • establishment of localization in cell • intracellular transport • regulation of defense response • regulation of response to external stimulus • negative regulation of inflammatory response • negative regulation of biological process • inflammatory response to antigenic stimulus • regulation of response to stress • regulation of immune system process • negative regulation of inflammatory response to antigenic stimulus • defense response • immune response • negative regulation of response to stimulus • negative regulation of immune response • regulation of inflammatory response to antigenic stimulus • response to external stimulus • regulation of inflammatory response • regulation of response to stimulus • negative regulation of immune system process • immune system process • negative regulation of response to external stimulus • negative regulation of defense response • regulation of immune response • inflammatory response • positive regulation of adenylate cyclase activity • positive regulation of molecular function • regulation of molecular function • positive regulation of cyclase activity • activation of adenylate cyclase activity • regulation of adenylate cyclase activity • regulation of catalytic activity • positive regulation of catalytic activity • positive regulation of lyase activity • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • cellular response to monoamine stimulus • renal system process • chemical homeostasis • multicellular organismal-level water homeostasis • multicellular organismal-level chemical homeostasis • renal water homeostasis • cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex
Gene Ontology	Cellular Component	• cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • membrane-bounded organelle • extracellular vesicle • extracellular organelle • extracellular region • organelle • extracellular space • vesicle • extracellular membrane-bounded organelle • intracellular anatomical structure • cytoplasm • cytosol • Golgi apparatus subcompartment • Golgi apparatus • organelle subcompartment • trans-Golgi network membrane • intracellular membrane-bounded organelle • endomembrane system • intracellular organelle • trans-Golgi network • organelle membrane • protein binding • binding • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular process • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • signal transduction • cell communication • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • response to oxygen-containing compound • cellular response to oxygen-containing compound • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to chemical stimulus • cellular response to alcohol • response to hormone • response to chemical • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection • photoreceptor cell cilium • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome • synapse • cell junction • G-protein beta-subunit binding • fibroblast proliferation • cation binding • ion binding • metal ion binding • small molecule binding • hydrolase activity, acting on glycosyl bonds • alpha-sialidase activity • hydrolase activity, hydrolyzing O-glycosyl compounds • exo-alpha-sialidase activity • taste receptor activity • molecular transducer activity • transmembrane signaling receptor activity • signaling receptor activity • bitter taste receptor activity • G protein-coupled receptor activity • carbohydrate metabolic process • catabolic process • oligosaccharide catabolic process • oligosaccharide metabolic process • carbohydrate catabolic process • primary metabolic process • metabolic process • membrane lipid metabolic process • sphingolipid catabolic process • ceramide metabolic process • ganglioside catabolic process • carbohydrate derivative catabolic process • glycosphingolipid catabolic process • lipid catabolic process • glycolipid metabolic process • glycosphingolipid metabolic process • liposaccharide metabolic process • carbohydrate derivative metabolic process • sphingolipid metabolic process • membrane lipid catabolic process • glycolipid catabolic process • ceramide catabolic process • amide metabolic process • ganglioside metabolic process • lipid metabolic process • detection of chemical stimulus involved in sensory perception of bitter taste • detection of chemical stimulus involved in sensory perception of taste • detection of stimulus • detection of chemical stimulus • sensory perception of bitter taste • detection of stimulus involved in sensory perception • detection of chemical stimulus involved in sensory perception
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	GOQ
PDB Residues	W:W:?1 W:W:?2
Environment Details	Open EMBL-EBI Page
Code	GOQ
Name	8-methoxy-6-nitro-naphtho[1,2-e][1,3]benzodioxole-5-carboxylic acid
Synonyms
Identifier
Formula	C17 H11 N O7
Molecular Weight	341.272
SMILES
PubChem	2236
Formal Charge	0
Total Atoms	36
Total Chiral Atoms	0
Total Bonds	39
Total Aromatic Bonds	16


Code	CLR
PDB Residues	L:L:?3
Environment Details	Open EMBL-EBI Page
Code	CLR
Name	Cholesterol
Synonyms	Cholesterin Cholesterol Cholest-5-en-3beta-ol (3β,14β,17α)-cholest-5-en-3-ol
Identifier
Formula	C27 H46 O
Molecular Weight	386.654
SMILES
PubChem	5997
Formal Charge	0
Total Atoms	74
Total Chiral Atoms	8
Total Bonds	77
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q9NYV8
Sequence	>8XQL_nogp_Chain_R G G V I K S I F T F V L I V E F I I G N L G N S F I A L V N C I D W V K G R K I S S V D R I L T A L A I S R I S L V W L I F G S W C V S V F F P A L F A T E K M F R M L T N I W T V I N H F S V W L A T G L G T F Y F L K I A N F S N S I F L Y L K W R V K K V V L V L L L V T S V F L F L N I A L I N I H I N A S I N G F T R F S S L I V L T S T V F I F I P F T L S L A M F L L L I F S M W K H R K K M Q H T V K I S G D A S T K A H R G V K S V I T F F L L Y A I F S L S F F I S V W T S E R L E E N L I I L S Q V M G M A Y P S C H S C V L I L G N K K L R Q A S L S V L L W L R Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8RQL	T2	Sensory	Taste2	TAS2R14	Homo sapiens	Flufenamic acid	Flufenamic acid	chim(NtGi1-Gt3)/β1/γ2	3.03	2024-11-27	10.1038/s41467-024-54157-6
	8RQL (No Gprot)	T2	Sensory	Taste2	TAS2R14	Homo sapiens	Flufenamic acid	Flufenamic acid		3.03	2024-11-27	10.1038/s41467-024-54157-6
	8XQT	T2	Sensory	Taste2	TAS2R14	Homo sapiens	Cholesterol	Cholesterol	Gi1/β1/γ1	2.94	2024-07-10	10.1038/s41586-024-07569-9
	8XQT (No Gprot)	T2	Sensory	Taste2	TAS2R14	Homo sapiens	Cholesterol	Cholesterol		2.94	2024-07-10	10.1038/s41586-024-07569-9
	8XQS	T2	Sensory	Taste2	TAS2R14	Homo sapiens	Cholesterol	Flufenamic acid	Gi1/β1/γ1	3.3	2024-07-10	10.1038/s41586-024-07569-9
	8XQS (No Gprot)	T2	Sensory	Taste2	TAS2R14	Homo sapiens	Cholesterol	Flufenamic acid		3.3	2024-07-10	10.1038/s41586-024-07569-9
	8XQO	T2	Sensory	Taste2	TAS2R14	Homo sapiens	Cholesterol	Aristolochic acid A	Gi1/β1/γ1	2.77	2024-07-10	10.1038/s41586-024-07569-9
	8XQO (No Gprot)	T2	Sensory	Taste2	TAS2R14	Homo sapiens	Cholesterol	Aristolochic acid A		2.77	2024-07-10	10.1038/s41586-024-07569-9
	8XQN	T2	Sensory	Taste2	TAS2R14	Homo sapiens	Cholesterol	Aristolochic acid A	Gi1/β1/γ1	3.05	2024-07-10	10.1038/s41586-024-07569-9
	8XQN (No Gprot)	T2	Sensory	Taste2	TAS2R14	Homo sapiens	Cholesterol	Aristolochic acid A		3.05	2024-07-10	10.1038/s41586-024-07569-9
	8XQR	T2	Sensory	Taste2	TAS2R14	Homo sapiens	-	Flufenamic acid	Gt3/β1/γ1	3.2	2024-07-10	10.1038/s41586-024-07569-9
	8XQR (No Gprot)	T2	Sensory	Taste2	TAS2R14	Homo sapiens	-	Flufenamic acid		3.2	2024-07-10	10.1038/s41586-024-07569-9
	8XQP	T2	Sensory	Taste2	TAS2R14	Homo sapiens	Cholesterol	Aristolochic acid A	Gt3/β1/γ1	3.29	2024-07-10	10.1038/s41586-024-07569-9
	8XQP (No Gprot)	T2	Sensory	Taste2	TAS2R14	Homo sapiens	Cholesterol	Aristolochic acid A		3.29	2024-07-10	10.1038/s41586-024-07569-9
	8XQL	T2	Sensory	Taste2	TAS2R14	Homo sapiens	Cholesterol	Aristolochic acid A	Gt3/β1/γ1	2.99	2024-07-10	10.1038/s41586-024-07569-9
	8XQL (No Gprot)	T2	Sensory	Taste2	TAS2R14	Homo sapiens	Cholesterol	Aristolochic acid A		2.99	2024-07-10	10.1038/s41586-024-07569-9

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 8XQL_nogp.zip

You can click to copy the link of this page to easily come back here later

or use this QR code to link and share this page.

You can also read or download a guide explaining the meaning of all files and numerical data.