Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index Hub Avg Int. Strength Num Of Links Community ConSurf
1R:R:I5 4.472544
2R:R:F9 8.3444
3R:R:L13 6.322554
4R:R:F17 14.535405
5R:R:F26 3.95408
6R:R:D45 6.5275468
7R:R:R55 10.1475419
8R:R:W66 5.78754
9R:R:F76 4.765433
10R:R:R83 6.154503
11R:R:W98 9.452579
12R:R:F106 7.212507
13R:R:F108 6.5425408
14R:R:F119 4.63489
15R:R:L141 6.8225408
16R:R:F175 4.52402
17R:R:F186 5.938504
18R:R:L201 4.3225409
19R:R:F236 5.15419
20R:R:F247 5.395403
21R:R:N260 6.1545
22R:R:I263 7.0725404
23R:R:Q266 7.15453
24R:R:Y272 13.3675415
25R:R:S274 5.0275407
26R:R:H276 13.894519
27R:R:L282 2.98506
28R:R:L287 7.06409
29W:W:?1 10.13610
30L:L:?2 10.4651000
   

Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index Node1 Node2 Recurrence Int. Strength Hub1? Hub2? Community ConSurf1 ConSurf2
1R:R:F9 R:R:I5 23.90846.28YesYes444
2R:R:K6 R:R:N260 13.71015.6NoYes045
3R:R:F9 R:R:I263 34.52316.28YesYes044
4R:R:F9 R:R:L264 17.164612.18YesNo044
5R:R:I263 R:R:L13 53.46887.14YesYes044
6R:R:L13 R:R:W66 21.4459.11YesYes544
7R:R:L13 R:R:V267 39.16984.47YesNo044
8R:R:L13 R:R:M270 36.58434.24YesNo044
9R:R:E16 R:R:V267 43.13425.7NoNo084
10R:R:E16 R:R:M270 39.4938.12NoNo084
11R:R:E16 R:R:S274 82.37588.62NoYes087
12R:R:F17 R:R:N21 11.68498.46YesNo056
13R:R:I56 R:R:N21 14.5724.25NoNo066
14R:R:I56 R:R:N24 20.30314.25NoNo069
15R:R:N24 R:R:R55 23.14716.03NoYes099
16R:R:H276 R:R:R55 21.911812.41YesYes199
17R:R:F236 R:R:H276 77.99484.53YesYes199
18R:R:C275 R:R:F236 82.06696.98NoYes049
19R:R:C275 R:R:S274 82.13883.44NoYes047
20R:R:F26 R:R:I281 19.67113.77YesNo089
21R:R:I281 R:R:L287 21.82567.14NoYes099
22R:R:L287 R:R:N284 40.555910.98YesNo099
23R:R:K286 R:R:N284 42.56684.2NoNo089
24R:R:D34 R:R:K286 44.38386.91NoNo068
25R:R:D34 R:R:R39 46.394710.72NoNo066
26R:R:K37 R:R:R39 48.362511.14NoNo066
27R:R:K37 R:R:V36 50.3163.04NoNo065
28R:R:V36 R:R:W35 52.25514.9NoNo055
29R:R:I41 R:R:W35 56.09023.52NoNo065
30R:R:D45 R:R:I41 57.78517YesNo686
31R:R:D45 R:R:S42 65.426610.31YesNo088
32R:R:S42 R:R:V44 69.06064.85NoNo086
33R:R:V44 R:R:Y107 70.68373.79NoNo069
34R:R:Y107 W:W:?1 1004.37NoYes090
35R:R:F237 W:W:?1 73.448715.14NoYes160
36R:R:F191 R:R:F237 83.35971.07NoNo076
37R:R:F188 R:R:F191 81.85871.07NoNo037
38R:R:F188 R:R:T184 81.11891.3NoNo035
39L:L:?2 R:R:T184 80.41514.41YesNo005
40L:L:?2 R:R:M268 27.743518.33YesNo005
41R:R:F247 R:R:M268 24.38243.73YesNo035
42R:R:F247 R:R:L264 17.95468.53YesNo034
43R:R:H276 W:W:?1 97.56548.79YesYes190
44R:R:I27 R:R:L287 13.4667.14NoYes099
45R:R:F106 R:R:I47 34.6385.02YesNo079
46R:R:I47 R:R:L103 36.56288.56NoNo099
47R:R:L103 R:R:Y107 38.52343.52NoNo099
48R:R:L51 R:R:R55 14.57217.01NoYes099
49L:L:?2 R:R:W89 26.350229.53YesNo004
50R:R:N93 R:R:W89 19.240214.69NoNo084
51R:R:L58 R:R:N93 17.38014.12NoNo048
52R:R:I92 R:R:L58 13.61684.28NoNo044
53R:R:F237 R:R:Y272 10.70816.19NoYes165
54R:R:C67 R:R:W66 15.9155.22NoYes044
55R:R:S69 R:R:W66 13.60963.71NoYes044
56R:R:F76 R:R:S69 14.27753.96YesNo034
57L:L:?2 R:R:F76 24.17413.64YesYes003
58R:R:S194 W:W:?1 82.54815.6NoYes080
59R:R:S194 R:R:T101 80.86046.4NoNo088
60R:R:T101 R:R:W98 79.15834.85NoYes089
61R:R:P190 R:R:W98 61.347317.57NoYes099
62R:R:I189 R:R:P190 55.72393.39NoNo069
63R:R:F186 R:R:I189 51.90326.28YesNo046
64R:R:F186 R:R:L147 44.06063.65YesNo044
65R:R:H151 R:R:L147 40.08196.43NoNo924
66R:R:H151 R:R:L178 38.1937.71NoNo023
67R:R:F175 R:R:L178 36.27553.65YesNo023
68R:R:F175 R:R:S155 24.09516.61YesNo023
69R:R:I156 R:R:S155 21.96214.64NoNo033
70R:R:I156 R:R:R83 19.80033.76NoYes033
71R:R:H94 R:R:W98 15.577411.64NoYes759
72R:R:H94 R:R:L141 13.437216.71NoYes058
73R:R:F198 W:W:?1 61.548417.41NoYes070
74R:R:F198 R:R:I202 59.73148.79NoNo078
75R:R:I202 R:R:R228 57.892812.53NoNo085
76R:R:H227 R:R:R228 32.59125.64NoNo1095
77R:R:H227 R:R:L201 32.87855.14NoYes099
78R:R:F108 R:R:L201 27.39164.87YesYes089
79R:R:F108 R:R:M197 13.264912.44YesNo088
80R:R:F106 R:R:V126 21.416310.49YesNo077
81R:R:L109 R:R:V126 19.49877.45NoNo077
82R:R:L109 R:R:V129 10.04024.47NoNo276
83R:R:A112 R:R:F108 12.22352.77NoYes088
84R:R:K211 R:R:M212 11.00985.76NoNo059
85R:R:D221 R:R:M212 15.18245.54NoNo089
86R:R:D221 R:R:T224 19.51311.45NoNo087
87R:R:M205 R:R:T224 23.58523.01NoNo097
88R:R:M205 R:R:R228 23.64264.96NoNo1095
89R:R:V233 R:R:V279 25.19394.81NoNo077
90R:R:L257 R:R:N260 20.28871.37NoYes015
91R:R:L257 R:R:S250 13.53784.5NoNo013
92R:R:I262 R:R:Q266 15.76419.61NoYes013
93R:R:L282 R:R:V233 13.941.49YesNo067
94R:R:F9 R:R:N260 19.98718.46YesYes445
95R:R:I263 R:R:K6 16.5477.27YesNo044
96L:L:?2 R:R:I262 16.43218.54YesNo001
97R:R:R55 R:R:Y272 17.99055.14YesYes195
98R:R:Y272 W:W:?1 13.9049.47YesYes150
99R:R:H276 R:R:V279 20.331811.07YesNo197
Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Links and nodes colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:L85 R:R:S65 6.01 0 No No 2 4 1 2
R:R:F76 R:R:V68 5.24 3 Yes No 3 3 1 2
R:R:M81 R:R:V68 6.09 3 No No 3 3 2 2
R:R:F76 R:R:S69 3.96 3 Yes No 3 4 1 2
R:R:F76 R:R:M81 6.22 3 Yes No 3 3 1 2
L:L:?2 R:R:F76 3.64 0 Yes Yes 0 3 0 1
R:R:E79 R:R:F82 9.33 0 No No 2 2 2 1
R:R:F82 R:R:T86 5.19 0 No No 2 3 1 2
L:L:?2 R:R:F82 3.64 0 Yes No 0 2 0 1
L:L:?2 R:R:L85 9.66 0 Yes No 0 2 0 1
R:R:T90 R:R:W89 3.64 0 No No 5 4 2 1
R:R:N93 R:R:W89 14.69 0 No No 8 4 2 1
L:L:?2 R:R:W89 29.53 0 Yes No 0 4 0 1
L:L:?2 R:R:V180 5.94 0 Yes No 0 3 0 1
L:L:?2 R:R:S183 4.49 0 Yes No 0 7 0 1
L:L:?2 R:R:T184 4.41 0 Yes No 0 5 0 1
R:R:F247 R:R:M268 3.73 0 Yes No 3 5 2 1
R:R:I262 R:R:Q266 9.61 0 No Yes 1 3 1 2
L:L:?2 R:R:I262 8.54 0 Yes No 0 1 0 1
L:L:?2 R:R:S265 16.47 0 Yes No 0 4 0 1
L:L:?2 R:R:M268 18.33 0 Yes No 0 5 0 1
R:R:G269 R:R:M268 1.75 0 No No 4 5 2 1
R:R:F188 R:R:T184 1.3 0 No No 3 5 2 1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

2D representation of the interactions of this orthosteric/allosteric ligand.


Links and nodes colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:V44 R:R:Y107 3.79 0 No No 6 9 2 1
R:R:R55 R:R:Y272 5.14 1 Yes Yes 9 5 2 1
R:R:H276 R:R:R55 12.41 1 Yes Yes 9 9 1 2
R:R:S194 R:R:T101 6.4 0 No No 8 8 1 2
R:R:L103 R:R:Y107 3.52 0 No No 9 9 2 1
R:R:Y107 W:W:?1 4.37 0 No Yes 9 0 1 0
R:R:S194 W:W:?1 5.6 0 No Yes 8 0 1 0
R:R:F198 R:R:I202 8.79 0 No No 7 8 1 2
R:R:F198 W:W:?1 17.41 0 No Yes 7 0 1 0
R:R:F236 R:R:H276 4.53 1 Yes Yes 9 9 2 1
R:R:F236 R:R:V279 3.93 1 Yes No 9 7 2 2
R:R:F237 R:R:Y272 6.19 1 No Yes 6 5 1 1
R:R:F237 W:W:?1 15.14 1 No Yes 6 0 1 0
R:R:H276 R:R:Y272 32.67 1 Yes Yes 9 5 1 1
R:R:Y272 W:W:?1 9.47 1 Yes Yes 5 0 1 0
R:R:H276 R:R:V279 11.07 1 Yes No 9 7 1 2
R:R:H276 W:W:?1 8.79 1 Yes Yes 9 0 1 0
R:R:F191 R:R:F237 1.07 0 No No 7 6 2 1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB 8XQP_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.
Net Summary
Imin 3.39
Number of Linked Nodes 263
Number of Links 277
Number of Hubs 30
Number of Links mediated by Hubs 124
Number of Communities 10
Number of Nodes involved in Communities 38
Number of Links involved in Communities 43
Path Summary
Number Of Nodes in MetaPath 100
Number Of Links MetaPath 99
Number of Shortest Paths 42192
Length Of Smallest Path 3
Average Path Length 15.2087
Length of Longest Path 35
Minimum Path Strength 1.07
Average Path Strength 6.60944
Maximum Path Strength 24.595
Minimum Path Correlation 0.7
Average Path Correlation 0.931714
Maximum Path Correlation 1
Minimum % Of Corr. Nodes 3.44828
Average % Of Corr. Nodes 41.9935
Maximum % Of Corr. Nodes 100
Minimum Path Hubs % 0
Average Path Hubs % 33.1688
Maximum Path Hubs % 100
AnnotationTypeLinks
Gene OntologyMolecular Function• protein-containing complex binding   • binding   • G-protein beta/gamma-subunit complex binding   • protein binding   • signaling receptor binding   • G protein-coupled receptor binding   • guanyl nucleotide binding   • GTP binding   • nucleotide binding   • guanyl ribonucleotide binding   • purine ribonucleotide binding   • purine ribonucleoside triphosphate binding   • nucleoside phosphate binding   • ion binding   • purine nucleotide binding   • anion binding   • heterocyclic compound binding   • carbohydrate derivative binding   • ribonucleotide binding   • small molecule binding   • cation binding   • metal ion binding   • pyrophosphatase activity   • GTPase activity   • ribonucleoside triphosphate phosphatase activity   • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides   • hydrolase activity   • hydrolase activity, acting on acid anhydrides   • catalytic activity   • sensory perception of sweet taste   • multicellular organismal process   • system process   • sensory perception of chemical stimulus   • sensory perception   • nervous system process   • sensory perception of taste   • detection of light stimulus involved in visual perception   • detection of light stimulus   • response to light stimulus   • detection of external stimulus   • sensory perception of light stimulus   • response to stimulus   • response to external stimulus
Gene OntologyBiological Process• sensory perception of sweet taste   • multicellular organismal process   • system process   • sensory perception of chemical stimulus   • sensory perception   • nervous system process   • sensory perception of taste   • detection of light stimulus involved in visual perception   • detection of light stimulus   • response to light stimulus   • detection of external stimulus   • sensory perception of light stimulus   • response to stimulus   • response to external stimulus   • detection of abiotic stimulus   • detection of stimulus   • detection of light stimulus involved in sensory perception   • response to abiotic stimulus   • response to radiation   • visual perception   • detection of stimulus involved in sensory perception   • sensory perception of umami taste   • phototransduction   • cellular response to stimulus   • regulation of biological process   • regulation of cellular process   • signaling   • biological regulation   • detection of visible light   • cell communication   • cellular process   • signal transduction   • phototransduction, visible light   • adenylate cyclase-modulating G protein-coupled receptor signaling pathway   • G protein-coupled receptor signaling pathway   • response to chemical   • response to nicotine   • sensory perception of bitter taste   • membrane-bounded organelle   • intracellular anatomical structure   • axoneme   • ciliary plasm   • cilium   • intracellular membraneless organelle   • cytoplasmic region   • plasma membrane bounded cell projection cytoplasm   • plasma membrane bounded cell projection   • intracellular organelle   • cell projection   • cellular anatomical structure   • cytoskeleton   • organelle
Gene OntologyCellular Component• membrane-bounded organelle   • intracellular anatomical structure   • axoneme   • ciliary plasm   • cilium   • intracellular membraneless organelle   • cytoplasmic region   • plasma membrane bounded cell projection cytoplasm   • plasma membrane bounded cell projection   • intracellular organelle   • cell projection   • cellular anatomical structure   • cytoskeleton   • organelle   • membraneless organelle   • cytoplasm   • protein-containing complex   • extrinsic component of plasma membrane   • catalytic complex   • plasma membrane protein complex   • cytoplasmic side of membrane   • membrane   • plasma membrane   • membrane protein complex   • heterotrimeric G-protein complex   • side of membrane   • cell periphery   • cytoplasmic side of plasma membrane   • GTPase complex   • extrinsic component of membrane   • extrinsic component of cytoplasmic side of plasma membrane   • apical part of cell   • plasma membrane region   • apical plasma membrane   • acrosomal vesicle   • intracellular vesicle   • intracellular membrane-bounded organelle   • endomembrane system   • cytoplasmic vesicle   • secretory granule   • secretory vesicle   • vesicle   • protein binding   • binding   • enzyme binding   • GTPase binding   • protein-containing complex binding   • pyrophosphatase activity   • GTPase activity   • ribonucleoside triphosphate phosphatase activity   • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides   • hydrolase activity   • hydrolase activity, acting on acid anhydrides   • catalytic activity   • signaling receptor complex adaptor activity   • protein-macromolecule adaptor activity   • molecular adaptor activity   • signaling adaptor activity   • multicellular organismal process   • system process   • sensory perception of chemical stimulus   • sensory perception   • nervous system process   • sensory perception of taste   • developmental process   • sensory organ development   • eye development   • animal organ development   • retina development in camera-type eye   • visual system development   • multicellular organism development   • camera-type eye development   • anatomical structure development   • sensory system development   • system development   • cell population proliferation   • cellular process   • cellular response to stimulus   • regulation of biological process   • regulation of cellular process   • response to stimulus   • signaling   • biological regulation   • signal transduction   • cell communication   • response to ketone   • response to prostaglandin   • response to lipid   • response to endogenous stimulus   • response to alcohol   • cellular response to prostaglandin stimulus   • response to oxygen-containing compound   • cellular response to oxygen-containing compound   • cellular response to endogenous stimulus   • cellular response to prostaglandin E stimulus   • cellular response to chemical stimulus   • cellular response to alcohol   • response to hormone   • response to chemical   • cellular response to lipid   • response to prostaglandin E   • cellular response to ketone   • cellular response to hormone stimulus   • small GTPase-mediated signal transduction   • Ras protein signal transduction   • intracellular signal transduction   • intracellular signaling cassette   • phospholipase C-activating G protein-coupled receptor signaling pathway   • G protein-coupled receptor signaling pathway   • cellular response to nitrogen compound   • response to dopamine   • cellular response to dopamine   • response to monoamine   • response to catecholamine   • adenylate cyclase-activating dopamine receptor signaling pathway   • cellular response to catecholamine stimulus   • G protein-coupled dopamine receptor signaling pathway   • response to nitrogen compound   • adenylate cyclase-activating G protein-coupled receptor signaling pathway   • cellular response to monoamine stimulus   • adenylate cyclase-modulating G protein-coupled receptor signaling pathway   • synaptic signaling   • cellular response to acetylcholine   • cell-cell signaling   • acetylcholine receptor signaling pathway   • postsynaptic signal transduction   • G protein-coupled acetylcholine receptor signaling pathway   • response to acetylcholine   • extracellular exosome   • extracellular vesicle   • extracellular organelle   • extracellular region   • extracellular space   • extracellular membrane-bounded organelle   • non-motile cilium   • 9+0 non-motile cilium   • neuron projection   • photoreceptor disc membrane   • photoreceptor outer segment   • photoreceptor cell cilium   • organelle membrane   • cytosol   • vacuolar membrane   • lytic vacuole   • vacuole   • lytic vacuole membrane   • bounding membrane of organelle   • lysosomal membrane   • lysosome   • synapse   • cell junction   • cation binding   • ion binding   • metal ion binding   • small molecule binding   • hydrolase activity, acting on glycosyl bonds   • alpha-sialidase activity   • hydrolase activity, hydrolyzing O-glycosyl compounds   • exo-alpha-sialidase activity   • taste receptor activity   • molecular transducer activity   • transmembrane signaling receptor activity   • signaling receptor activity   • bitter taste receptor activity   • G protein-coupled receptor activity   • membrane lipid metabolic process   • sphingolipid catabolic process   • ceramide metabolic process   • ganglioside catabolic process   • carbohydrate derivative catabolic process   • glycosphingolipid catabolic process   • catabolic process   • lipid catabolic process   • glycolipid metabolic process   • glycosphingolipid metabolic process   • liposaccharide metabolic process   • carbohydrate derivative metabolic process   • primary metabolic process   • sphingolipid metabolic process   • membrane lipid catabolic process   • glycolipid catabolic process   • ceramide catabolic process   • metabolic process   • amide metabolic process   • ganglioside metabolic process   • lipid metabolic process   • carbohydrate metabolic process   • oligosaccharide catabolic process   • oligosaccharide metabolic process   • carbohydrate catabolic process   • detection of chemical stimulus involved in sensory perception of bitter taste   • detection of chemical stimulus involved in sensory perception of taste   • detection of stimulus   • detection of chemical stimulus   • sensory perception of bitter taste   • detection of stimulus involved in sensory perception   • detection of chemical stimulus involved in sensory perception   • G-protein beta-subunit binding   • fibroblast proliferation
SCOP2Domain Identifier• Transducin (heterotrimeric G protein), gamma chain
SCOP2Family Identifier• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations-• Orientations of Proteins in Membranes database (OPM)   • Protein Data Bank of Transmembrane Proteins (PDBTM)   • MemProtMD


Details about the values in these tables can be found in the corresponding documentation page .
CodeGOQ
PDB ResiduesW:W:?1
Environment DetailsOpen EMBL-EBI Page
CodeGOQ
Name8-methoxy-6-nitro-naphtho[1,2-e][1,3]benzodioxole-5-carboxylic acid
Synonyms
Identifier
FormulaC17 H11 N O7
Molecular Weight341.272
SMILES
PubChem2236
Formal Charge0
Total Atoms36
Total Chiral Atoms0
Total Bonds39
Total Aromatic Bonds16

CodeCLR
PDB ResiduesL:L:?2
Environment DetailsOpen EMBL-EBI Page
CodeCLR
NameCholesterol
Synonyms
  • Cholesterol
  • Cholesterin
  • Cholest-5-en-3beta-ol
  • (3β,14β,17α)-cholest-5-en-3-ol
Identifier
FormulaC27 H46 O
Molecular Weight386.654
SMILES
PubChem5997
Formal Charge0
Total Atoms74
Total Chiral Atoms8
Total Bonds77
Total Aromatic Bonds0

PDBsumOpen PDBsum Page
ChainR
ProteinReceptor
UniProtQ9NYV8
Sequence
>8XQP_nogp_Chain_R
GGVIKSIFT FVLIVEFII GNLGNSFIA LVNCIDWVK GRKISSVDR 
ILTALAISR ISLVWLIFG SWCVSVFFP ALFATEKMF RMLTNIWTV 
INHFSVWLA TGLGTFYFL KIANFSNSI FLYLKWRVK KVVLVLLLV 
TSVFLFLNI ALINIHINA SINGYRRNF TRFSSLIVL TSTVFIFIP 
FTLSLAMFL LLIFSMWKH RKKMQHTVK DASTKAHRG VKSVITFFL 
LYAIFSLSF FISVWTSER LEENLIILS QVMGMAYPS CHSCVLILG 
NKKLRQASL SVLLWLR


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  




This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
8RQLT2SensoryTaste2TAS2R14Homo sapiensFlufenamic acidFlufenamic acidchim(NtGi1-Gt3)/β1/γ23.032024-11-27doi.org/10.1038/s41467-024-54157-6
8RQL (No Gprot) T2SensoryTaste2TAS2R14Homo sapiensFlufenamic acidFlufenamic acid3.032024-11-27doi.org/10.1038/s41467-024-54157-6
8XQRT2SensoryTaste2TAS2R14Homo sapiens-Flufenamic acidGt3/β1/γ13.22024-07-10doi.org/10.1038/s41586-024-07569-9
8XQR (No Gprot) T2SensoryTaste2TAS2R14Homo sapiens-Flufenamic acid3.22024-07-10doi.org/10.1038/s41586-024-07569-9
8XQST2SensoryTaste2TAS2R14Homo sapiensCholesterolFlufenamic acidGi1/β1/γ13.32024-07-10doi.org/10.1038/s41586-024-07569-9
8XQS (No Gprot) T2SensoryTaste2TAS2R14Homo sapiensCholesterolFlufenamic acid3.32024-07-10doi.org/10.1038/s41586-024-07569-9
8XQLT2SensoryTaste2TAS2R14Homo sapiensCholesterolAristolochic acid AGt3/β1/γ12.992024-07-10doi.org/10.1038/s41586-024-07569-9
8XQL (No Gprot) T2SensoryTaste2TAS2R14Homo sapiensCholesterolAristolochic acid A2.992024-07-10doi.org/10.1038/s41586-024-07569-9
8XQNT2SensoryTaste2TAS2R14Homo sapiensCholesterolAristolochic acid AGi1/β1/γ13.052024-07-10doi.org/10.1038/s41586-024-07569-9
8XQN (No Gprot) T2SensoryTaste2TAS2R14Homo sapiensCholesterolAristolochic acid A3.052024-07-10doi.org/10.1038/s41586-024-07569-9
8XQOT2SensoryTaste2TAS2R14Homo sapiensCholesterolAristolochic acid AGi1/β1/γ12.772024-07-10doi.org/10.1038/s41586-024-07569-9
8XQO (No Gprot) T2SensoryTaste2TAS2R14Homo sapiensCholesterolAristolochic acid A2.772024-07-10doi.org/10.1038/s41586-024-07569-9
8XQPT2SensoryTaste2TAS2R14Homo sapiensCholesterolAristolochic acid AGt3/β1/γ13.292024-07-10doi.org/10.1038/s41586-024-07569-9
8XQP (No Gprot) T2SensoryTaste2TAS2R14Homo sapiensCholesterolAristolochic acid A3.292024-07-10doi.org/10.1038/s41586-024-07569-9
8XQTT2SensoryTaste2TAS2R14Homo sapiensCholesterol-Gi1/β1/γ12.942024-07-10doi.org/10.1038/s41586-024-07569-9
8XQT (No Gprot) T2SensoryTaste2TAS2R14Homo sapiensCholesterol-2.942024-07-10doi.org/10.1038/s41586-024-07569-9




You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 8XQP_nogp.zip



You can click to copy the link of this page to easily come back here later

or use this QR code to link and share this page.



You can also  read or  download a guide explaining the meaning of all files and numerical data.