psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	E:E:C27	E:E:E29	3.04	No	No	0	8	5
2	E:E:C27	E:E:L80	4.76	No	No	13	8	6
3	E:E:C27	E:E:C82	7.28	No	No	13	8	8
4	E:E:A30	E:E:Q28	3.03	No	No	0	4	4
5	E:E:E29	E:E:N86	5.26	No	Yes	0	5	9
6	E:E:L35	E:E:N31	5.49	Yes	No	0	2	2
7	E:E:A77	E:E:Y32	4	No	Yes	0	8	5
8	E:E:N86	E:E:Y32	12.79	Yes	Yes	1	9	5
9	E:E:E88	E:E:Y32	3.37	Yes	Yes	1	4	5
10	E:E:V89	E:E:Y32	3.79	No	Yes	1	8	5
11	E:E:E88	E:E:G33	6.55	Yes	No	0	4	5
12	E:E:L35	E:E:L39	4.15	Yes	No	14	2	1
13	E:E:K79	E:E:L35	2.82	No	Yes	0	2	2
14	E:E:L36	E:E:T73	2.95	No	No	0	5	9
15	E:E:F92	E:E:L36	8.53	Yes	No	0	5	5
16	E:E:L41	E:E:R37	4.86	No	No	0	5	3
17	E:E:L39	E:E:M76	4.24	No	No	0	1	4
18	E:E:C40	E:E:C72	7.28	No	No	0	9	9
19	E:E:L41	E:E:Q45	3.99	No	No	0	5	4
20	E:E:F92	E:E:L41	7.31	Yes	No	0	5	5
21	E:E:Q45	E:E:T42	2.83	No	No	0	4	2
22	E:E:Q43	E:E:V46	4.3	No	No	1	1	1
23	E:E:D47	E:E:Q43	6.53	Yes	No	1	5	1
24	E:E:F44	E:E:M48	3.73	Yes	Yes	1	9	9
25	E:E:F44	E:E:L69	14.61	Yes	No	0	9	8
26	E:E:F44	E:E:V96	3.93	Yes	No	0	9	8
27	E:E:F44	E:E:Y100	3.09	Yes	Yes	1	9	8
28	E:E:D47	E:E:V46	4.38	Yes	No	1	5	1
29	E:E:D47	E:E:R64	3.57	Yes	No	1	5	5
30	E:E:D47	E:E:S65	5.89	Yes	No	1	5	4
31	E:E:M48	E:E:W56	12.8	Yes	Yes	1	9	5
32	E:E:M48	E:E:T62	3.01	Yes	No	1	9	8
33	E:E:M48	E:E:Y100	13.17	Yes	Yes	1	9	8
34	E:E:F101	E:E:M48	4.98	Yes	Yes	1	9	9
35	E:E:E53	E:E:W56	6.54	No	Yes	0	4	5
36	E:E:W56	E:E:Y100	14.47	Yes	Yes	1	5	8
37	E:E:C104	E:E:C57	7.28	No	No	0	9	9
38	E:E:D58	E:E:G60	3.35	No	No	0	5	4
39	E:E:T62	E:E:W59	3.64	No	Yes	1	8	7
40	E:E:I63	E:E:W59	10.57	No	Yes	1	5	7
41	E:E:W59	R:R:D50	4.47	Yes	No	1	7	2
42	E:E:W59	R:R:Y53	19.29	Yes	Yes	1	7	1
43	E:E:F101	E:E:T62	5.19	Yes	No	1	9	8
44	E:E:I63	R:R:M49	4.37	No	Yes	1	5	4
45	E:E:I63	R:R:D50	2.8	No	No	1	5	2
46	E:E:R64	E:E:S65	6.59	No	No	1	5	4
47	E:E:E68	E:E:R64	3.49	No	No	0	4	5
48	E:E:F93	E:E:Y66	10.32	Yes	Yes	1	9	9
49	E:E:H97	E:E:Y66	6.53	Yes	Yes	1	9	9
50	E:E:F101	E:E:Y66	4.13	Yes	Yes	1	9	9
51	E:E:Y66	R:R:Y53	5.96	Yes	Yes	1	9	1
52	E:E:R67	R:R:R45	3.2	No	Yes	1	5	7
53	E:E:R67	R:R:K46	3.71	No	No	0	5	4
54	E:E:R67	R:R:M49	3.72	No	Yes	1	5	4
55	E:E:F92	E:E:L69	7.31	Yes	No	0	5	8
56	E:E:F93	E:E:L69	4.87	Yes	No	0	9	8
57	E:E:A70	R:R:M49	3.22	No	Yes	1	8	4
58	E:E:A70	R:R:Q52	3.03	No	Yes	1	8	6
59	E:E:D71	E:E:H75	8.82	No	No	0	3	2
60	E:E:D71	R:R:R45	4.76	No	Yes	0	3	7
61	E:E:T73	E:E:W84	8.49	No	Yes	1	9	7
62	E:E:T73	E:E:V89	7.93	No	No	1	9	8
63	E:E:H75	E:E:W74	12.7	No	No	0	2	6
64	E:E:E78	E:E:W74	22.9	No	No	0	4	6
65	E:E:W74	E:E:W84	5.62	No	Yes	0	6	7
66	E:E:K79	E:E:L80	4.23	No	No	0	2	6
67	E:E:C82	E:E:L80	3.17	No	No	13	8	6
68	E:E:F83	R:R:N124	9.67	No	No	0	5	5
69	E:E:F83	R:R:R126	23.52	No	No	0	5	4
70	E:E:P85	E:E:W84	18.92	No	Yes	0	9	7
71	E:E:V89	E:E:W84	6.13	No	Yes	1	8	7
72	E:E:W84	L:L:?37	3.69	Yes	Yes	1	7	0
73	E:E:W84	R:R:Q52	4.38	Yes	Yes	1	7	6
74	E:E:P85	R:R:W76	4.05	No	Yes	0	9	8
75	E:E:P85	R:R:G78	4.06	No	No	0	9	5
76	E:E:E88	E:E:N86	3.94	Yes	Yes	1	4	9
77	E:E:E88	E:E:R91	10.47	Yes	No	0	4	3
78	E:E:D90	R:R:Y56	8.05	No	Yes	1	8	3
79	E:E:D90	R:R:T75	2.89	No	No	0	8	5
80	E:E:D90	R:R:W76	4.47	No	Yes	1	8	8
81	E:E:F92	E:E:V96	5.24	Yes	No	0	5	8
82	E:E:F93	R:R:Q52	9.37	Yes	Yes	1	9	6
83	E:E:F93	R:R:Y56	15.47	Yes	Yes	1	9	3
84	E:E:L94	R:R:Y56	3.52	No	Yes	1	7	3
85	E:E:L94	R:R:M59	4.24	No	Yes	1	7	5
86	E:E:H97	R:R:Y53	7.62	Yes	Yes	1	9	1
87	E:E:H97	R:R:Y56	10.89	Yes	Yes	1	9	3
88	E:E:H97	R:R:D57	13.87	Yes	No	1	9	4
89	E:E:H97	R:R:Q60	6.18	Yes	No	1	9	3
90	E:E:G98	E:E:R102	6	No	No	0	5	5
91	E:E:R99	E:E:Y100	10.29	No	Yes	0	4	8
92	E:E:F101	E:E:Y100	4.13	Yes	Yes	1	9	8
93	E:E:F101	R:R:Y53	14.44	Yes	Yes	1	9	1
94	E:E:S103	R:R:Q61	4.33	No	No	0	7	3
95	E:E:R109	E:E:R112	8.53	No	No	0	6	4
96	E:E:P115	E:E:R109	2.88	No	No	0	9	6
97	E:E:R109	R:R:Y284	7.2	No	No	0	6	2
98	E:E:V111	R:R:F285	9.18	No	Yes	0	5	6
99	E:E:D113	E:E:P114	3.22	Yes	Yes	0	9	9
100	E:E:D113	R:R:F285	5.97	Yes	Yes	2	9	6
101	E:E:D113	R:R:T295	8.67	Yes	Yes	2	9	4
102	E:E:D113	R:R:H296	3.78	Yes	No	0	9	2
103	E:E:L119	E:E:P114	3.28	No	Yes	0	8	9
104	E:E:P114	R:R:Y284	15.3	Yes	No	0	9	2
105	E:E:P114	R:R:L297	4.93	Yes	Yes	0	9	4
106	E:E:G116	E:E:Y120	5.79	No	No	0	5	5
107	E:E:L119	R:R:H296	3.86	No	No	0	8	2
108	E:E:F122	R:R:T280	3.89	No	No	0	9	4
109	E:E:P126	E:E:V125	3.53	No	No	0	9	6
110	E:E:P126	R:R:I300	3.39	No	Yes	0	9	8
111	E:E:I127	R:R:G303	3.53	No	No	6	8	4
112	E:E:I127	R:R:P304	6.77	No	No	6	8	9
113	E:E:T130	R:R:F235	3.89	No	Yes	6	9	5
114	E:E:T130	R:R:F269	6.49	No	Yes	6	9	3
115	E:E:T130	R:R:P304	6.99	No	No	6	9	9
116	E:E:V133	R:R:F269	11.8	No	Yes	0	8	3
117	E:E:T134	R:R:L238	7.37	No	Yes	0	8	8
118	E:E:V137	R:R:I242	4.61	No	Yes	0	9	7
119	E:E:V137	R:R:L265	7.45	No	Yes	0	9	7
120	E:E:V138	R:R:I242	6.14	No	Yes	0	9	7
121	E:E:Q140	E:E:W139	10.95	Yes	No	0	8	6
122	E:E:Q140	E:E:R143	5.84	Yes	No	10	8	7
123	E:E:Q140	R:R:R258	10.51	Yes	Yes	10	8	5
124	E:E:Q140	R:R:W261	16.43	Yes	Yes	10	8	2
125	E:E:S141	R:R:T246	7.99	No	No	0	9	7
126	E:E:K142	R:R:V250	4.55	No	No	0	9	5
127	E:E:R143	R:R:R258	10.66	No	Yes	10	7	5
128	H:H:?1	L:L:K24	3.71	Yes	No	5	0	0
129	H:H:?1	L:L:?101	5.32	Yes	Yes	5	0	0
130	H:H:?1	R:R:Y150	7.19	Yes	Yes	5	0	4
131	H:H:?1	R:R:I153	5	Yes	No	5	0	7
132	H:H:?1	R:R:S157	9.21	Yes	No	0	0	7
133	H:H:?2	R:R:N73	32.03	No	No	0	0	4
134	H:H:?3	R:R:N125	27.11	No	No	0	0	7
135	H:H:?4	R:R:W128	7.15	Yes	Yes	1	0	5
136	H:H:?4	R:R:N130	28.34	Yes	Yes	1	0	8
137	H:H:?4	R:R:M133	7.61	Yes	Yes	1	0	5
138	L:L:A1	R:R:E294	4.53	No	No	0	0	3
139	L:L:C2	L:L:T4	3.38	Yes	Yes	2	0	0
140	L:L:C2	L:L:C7	7.28	Yes	No	2	0	0
141	L:L:C2	R:R:L298	4.76	Yes	No	0	0	6
142	L:L:C2	R:R:H302	4.42	Yes	Yes	2	0	6
143	L:L:D3	R:R:W361	10.05	No	No	0	0	4
144	L:L:T4	L:L:T6	4.71	Yes	Yes	2	0	0
145	L:L:C7	L:L:T4	3.38	No	Yes	2	0	0
146	L:L:T4	R:R:M306	4.52	Yes	No	2	0	4
147	L:L:A5	R:R:F356	4.16	No	Yes	0	0	7
148	L:L:T6	R:R:Y234	8.74	Yes	Yes	0	0	7
149	L:L:T6	R:R:H302	9.58	Yes	Yes	2	0	6
150	L:L:T6	R:R:M306	6.02	Yes	No	2	0	4
151	L:L:C7	R:R:H302	10.32	No	Yes	2	0	6
152	L:L:R11	L:L:V8	3.92	No	No	0	0	0
153	L:L:V8	R:R:H377	6.92	No	Yes	0	0	7
154	L:L:V8	R:R:I380	4.61	No	No	0	0	6
155	L:L:T9	R:R:I198	3.04	No	Yes	0	0	7
156	L:L:H10	R:R:H226	7.17	No	No	0	0	6
157	L:L:H10	R:R:M230	6.57	No	Yes	2	0	6
158	L:L:H10	R:R:H302	8.36	No	Yes	2	0	6
159	L:L:R11	R:R:V293	3.92	No	No	0	0	6
160	L:L:L12	L:L:L16	4.15	No	No	0	0	0
161	L:L:L12	R:R:L148	2.77	No	Yes	7	0	5
162	L:L:L12	R:R:H377	6.43	No	Yes	7	0	7
163	L:L:A13	R:R:H201	2.93	No	Yes	0	0	6
164	L:L:L15	L:L:S19	3	No	No	15	0	0
165	L:L:L15	R:R:K141	4.23	No	No	0	0	3
166	L:L:L15	R:R:L142	4.15	No	Yes	15	0	2
167	L:L:L16	R:R:A145	3.15	No	No	0	0	4
168	L:L:L16	R:R:Y149	3.52	No	Yes	0	0	5
169	L:L:S17	R:R:L291	4.5	No	Yes	0	0	6
170	L:L:R18	R:R:P104	5.76	No	No	0	0	3
171	L:L:S19	R:R:L142	6.01	No	Yes	15	0	2
172	L:L:G21	L:L:K24	3.49	No	No	0	0	0
173	L:L:F27	L:L:V22	5.24	No	No	0	0	0
174	L:L:V23	R:R:L142	4.47	No	Yes	0	0	2
175	L:L:V23	R:R:Y146	10.09	No	No	0	0	2
176	L:L:?101	L:L:K24	12.36	Yes	No	5	0	0
177	L:L:F27	R:R:D101	4.78	No	Yes	0	0	4
178	L:L:P29	L:L:V28	3.53	No	No	0	0	0
179	L:L:T30	R:R:F99	20.75	Yes	Yes	1	0	5
180	L:L:T30	R:R:D101	8.67	Yes	Yes	1	0	4
181	L:L:T30	R:R:F102	5.19	Yes	Yes	1	0	4
182	L:L:T30	R:R:N135	2.92	Yes	No	1	0	3
183	L:L:S34	R:R:H121	6.97	No	No	0	0	4
184	L:L:S34	R:R:E123	10.06	No	No	0	0	4
185	L:L:K35	R:R:N124	4.2	No	No	0	0	5
186	L:L:?37	L:L:A36	3.83	Yes	No	0	0	0
187	L:L:?37	R:R:D77	3.3	Yes	Yes	1	0	9
188	L:L:?37	R:R:G78	8.32	Yes	No	1	0	5
189	L:L:?37	R:R:W79	9.23	Yes	Yes	1	0	6
190	L:L:?37	R:R:R126	7.87	Yes	No	0	0	4
191	L:L:?37	R:R:W128	6.46	Yes	Yes	1	0	5
192	L:L:?37	R:R:S129	6.08	Yes	Yes	1	0	7
193	L:L:?37	R:R:Y131	3.8	Yes	Yes	1	0	5
194	L:L:?101	R:R:Y146	11.3	Yes	No	5	0	2
195	L:L:?101	R:R:Y150	10.28	Yes	Yes	5	0	4
196	L:L:?101	R:R:L151	3.64	Yes	No	0	0	5
197	L:L:?101	R:R:V154	3.92	Yes	No	0	0	6
198	R:R:G44	R:R:K47	5.23	No	No	0	4	4
199	R:R:M49	R:R:R45	4.96	Yes	Yes	1	4	7
200	R:R:D97	R:R:K47	6.91	No	No	0	2	4
201	R:R:M48	R:R:W79	5.82	No	Yes	1	6	6
202	R:R:M48	R:R:Y98	9.58	No	Yes	1	6	4
203	R:R:M49	R:R:Q52	5.44	Yes	Yes	1	4	6
204	R:R:Q52	R:R:Y56	5.64	Yes	Yes	1	6	3
205	R:R:Q52	R:R:W76	12.05	Yes	Yes	1	6	8
206	R:R:D57	R:R:Y53	13.79	No	Yes	1	4	1
207	R:R:C55	R:R:M59	3.24	No	Yes	1	9	5
208	R:R:C55	R:R:W76	10.45	No	Yes	1	9	8
209	R:R:C55	R:R:C81	7.28	No	No	1	9	9
210	R:R:M59	R:R:Y56	3.59	Yes	Yes	1	5	3
211	R:R:W76	R:R:Y56	8.68	Yes	Yes	1	8	3
212	R:R:D57	R:R:Q60	5.22	No	No	1	4	3
213	R:R:L62	R:R:R58	3.64	No	No	0	3	3
214	R:R:D83	R:R:R58	5.96	No	No	0	5	3
215	R:R:M59	R:R:R74	9.93	Yes	No	0	5	4
216	R:R:L62	R:R:P63	6.57	No	No	0	3	1
217	R:R:E68	R:R:Y65	5.61	No	Yes	4	1	3
218	R:R:Y65	R:R:Y71	17.87	Yes	No	4	3	3
219	R:R:D84	R:R:Y65	4.6	No	Yes	4	4	3
220	R:R:P86	R:R:Y65	5.56	Yes	Yes	4	2	3
221	R:R:E68	R:R:P86	6.29	No	Yes	4	1	2
222	R:R:G69	R:R:P70	4.06	No	No	0	1	1
223	R:R:D84	R:R:Y71	8.05	No	No	4	4	3
224	R:R:C72	R:R:T85	3.38	No	Yes	4	9	7
225	R:R:C112	R:R:C72	5.46	No	No	4	9	9
226	R:R:C72	R:R:W118	5.22	No	Yes	4	9	9
227	R:R:N73	R:R:R74	3.62	No	No	0	4	4
228	R:R:D84	R:R:R74	19.06	No	No	0	4	4
229	R:R:T75	R:R:W118	12.13	No	Yes	0	5	9
230	R:R:C81	R:R:W76	3.92	No	Yes	1	9	8
231	R:R:D77	R:R:G78	3.35	Yes	No	1	9	5
232	R:R:D77	R:R:L80	4.07	Yes	Yes	1	9	5
233	R:R:D77	R:R:W82	8.93	Yes	No	0	9	9
234	R:R:D77	R:R:S129	4.42	Yes	Yes	1	9	7
235	R:R:D77	R:R:Y131	5.75	Yes	Yes	1	9	5
236	R:R:W79	R:R:Y98	5.79	Yes	Yes	1	6	4
237	R:R:F99	R:R:W79	9.02	Yes	Yes	1	5	6
238	R:R:F102	R:R:W79	7.02	Yes	Yes	1	4	6
239	R:R:W79	R:R:Y131	19.29	Yes	Yes	1	6	5
240	R:R:L80	R:R:Q93	3.99	Yes	No	0	5	6
241	R:R:L80	R:R:P96	11.49	Yes	Yes	1	5	9
242	R:R:L80	R:R:V108	4.47	Yes	No	1	5	7
243	R:R:L80	R:R:Y131	5.86	Yes	Yes	1	5	5
244	R:R:Q93	R:R:W82	19.71	No	No	0	6	9
245	R:R:K110	R:R:W82	19.73	Yes	No	0	8	9
246	R:R:P86	R:R:T85	3.5	Yes	Yes	4	2	7
247	R:R:S91	R:R:T85	6.4	No	Yes	0	5	7
248	R:R:C112	R:R:T85	3.38	No	Yes	4	9	7
249	R:R:T85	R:R:W118	8.49	Yes	Yes	4	7	9
250	R:R:P86	R:R:V89	10.6	Yes	No	0	2	5
251	R:R:G88	R:R:Y111	2.9	No	No	0	8	4
252	R:R:L90	R:R:Y92	5.86	No	No	1	4	4
253	R:R:L90	R:R:T109	4.42	No	Yes	1	4	5
254	R:R:L90	R:R:Y111	5.86	No	No	0	4	4
255	R:R:K107	R:R:Y92	11.94	No	No	0	3	4
256	R:R:T109	R:R:Y92	6.24	Yes	No	1	5	4
257	R:R:F94	R:R:K107	7.44	No	No	0	3	3
258	R:R:C95	R:R:P96	3.77	No	Yes	1	9	9
259	R:R:C95	R:R:F102	6.98	No	Yes	1	9	4
260	R:R:C134	R:R:C95	7.28	No	No	1	9	9
261	R:R:P96	R:R:Y98	13.91	Yes	Yes	1	9	4
262	R:R:F102	R:R:P96	2.89	Yes	Yes	1	4	9
263	R:R:F99	R:R:Y98	3.09	Yes	Yes	1	5	4
264	R:R:D101	R:R:F99	3.58	Yes	Yes	1	4	5
265	R:R:F102	R:R:F99	12.86	Yes	Yes	1	4	5
266	R:R:D101	R:R:N135	12.12	Yes	No	1	4	3
267	R:R:C134	R:R:F102	5.59	No	Yes	1	9	4
268	R:R:F102	R:R:N135	7.25	Yes	No	1	4	3
269	R:R:D103	R:R:P104	6.44	Yes	No	0	3	3
270	R:R:D103	R:R:S105	8.83	Yes	No	1	3	1
271	R:R:D103	R:R:E106	6.5	Yes	Yes	1	3	4
272	R:R:D103	R:R:K141	2.77	Yes	No	0	3	3
273	R:R:E106	R:R:S105	4.31	Yes	No	1	4	1
274	R:R:E106	R:R:M133	2.71	Yes	Yes	1	4	5
275	R:R:E106	R:R:F137	3.5	Yes	No	0	4	1
276	R:R:V108	R:R:Y131	10.09	No	Yes	1	7	5
277	R:R:N130	R:R:T109	4.39	Yes	Yes	1	8	5
278	R:R:M133	R:R:T109	3.01	Yes	Yes	1	5	5
279	R:R:K110	R:R:W118	15.08	Yes	Yes	0	8	9
280	R:R:K110	R:R:T127	3	Yes	No	0	8	4
281	R:R:K110	R:R:S129	10.71	Yes	Yes	0	8	7
282	R:R:C112	R:R:W118	5.22	No	Yes	4	9	9
283	R:R:D113	R:R:E114	10.39	No	No	0	5	2
284	R:R:H121	R:R:P122	10.68	No	No	0	4	5
285	R:R:H121	R:R:W128	19.04	No	Yes	0	4	5
286	R:R:E123	R:R:N124	13.15	No	No	0	4	5
287	R:R:N130	R:R:W128	7.91	Yes	Yes	1	8	5
288	R:R:S129	R:R:Y131	5.09	Yes	Yes	1	7	5
289	R:R:N130	R:R:T132	4.39	Yes	No	0	8	6
290	R:R:M133	R:R:N130	5.61	Yes	Yes	1	5	8
291	R:R:A136	R:R:F137	8.32	No	No	0	2	1
292	R:R:F137	R:R:K366	6.2	No	No	0	1	3
293	R:R:P139	R:R:T138	3.5	No	No	0	3	2
294	R:R:K370	R:R:N144	2.8	No	No	7	4	4
295	R:R:N144	R:R:Y374	4.65	No	Yes	7	4	6
296	R:R:Y146	R:R:Y150	3.97	No	Yes	5	2	4
297	R:R:V147	R:R:Y374	5.05	No	Yes	0	4	6
298	R:R:D373	R:R:L148	5.43	No	Yes	0	5	5
299	R:R:L148	R:R:Y374	4.69	Yes	Yes	7	5	6
300	R:R:H377	R:R:L148	18	Yes	Yes	7	7	5
301	R:R:Y149	R:R:Y150	11.91	Yes	Yes	5	5	4
302	R:R:I153	R:R:Y149	8.46	No	Yes	5	7	5
303	R:R:L202	R:R:Y149	4.69	Yes	Yes	5	7	5
304	R:R:L151	R:R:S378	6.01	No	No	0	5	5
305	R:R:F382	R:R:L151	3.65	No	No	0	7	5
306	R:R:A152	R:R:H381	7.32	No	No	0	7	9
307	R:R:I153	R:R:L202	2.85	No	Yes	5	7	7
308	R:R:F382	R:R:G155	9.03	No	No	0	7	8
309	R:R:H156	R:R:S195	11.16	No	No	0	7	7
310	R:R:H156	R:R:I198	11.93	No	Yes	0	7	7
311	R:R:H156	R:R:H381	10.75	No	No	0	7	9
312	R:R:I199	R:R:S157	3.1	No	No	0	7	7
313	R:R:F385	R:R:L158	7.31	Yes	No	0	5	4
314	R:R:G384	R:R:S159	3.71	No	No	0	9	9
315	R:R:I160	R:R:S195	4.64	No	No	0	5	7
316	R:R:F161	R:R:I165	3.77	No	No	0	4	5
317	R:R:F385	R:R:T162	7.78	Yes	No	0	5	6
318	R:R:A388	R:R:T162	3.36	No	No	0	8	6
319	R:R:F393	R:R:T162	3.89	Yes	No	0	8	6
320	R:R:F188	R:R:L163	4.87	Yes	No	0	8	8
321	R:R:I192	R:R:L163	5.71	No	No	0	7	8
322	R:R:A388	R:R:L163	3.15	No	No	0	8	8
323	R:R:F393	R:R:I165	3.77	Yes	No	0	8	5
324	R:R:F188	R:R:S166	5.28	Yes	No	0	8	9
325	R:R:A388	R:R:S166	3.42	No	No	0	8	9
326	R:R:C392	R:R:S166	6.89	No	No	0	9	9
327	R:R:L167	R:R:V171	2.98	No	No	0	6	4
328	R:R:K185	R:R:L167	4.23	No	No	0	6	6
329	R:R:F173	R:R:I169	7.54	Yes	No	0	7	8
330	R:R:F170	R:R:V181	10.49	Yes	Yes	11	8	9
331	R:R:F170	R:R:K185	3.72	Yes	No	11	8	6
332	R:R:F170	R:R:F188	5.36	Yes	Yes	0	8	8
333	R:R:C392	R:R:F170	6.98	No	Yes	0	9	8
334	R:R:F172	R:R:F173	8.57	No	Yes	8	2	7
335	R:R:F172	R:R:Q405	5.86	No	No	8	2	4
336	R:R:F173	R:R:T401	3.89	Yes	Yes	8	7	7
337	R:R:F173	R:R:Q405	9.37	Yes	No	8	7	4
338	R:R:L176	R:R:S175	3	No	No	8	9	8
339	R:R:S175	R:R:T401	3.2	No	Yes	8	8	7
340	R:R:L176	R:R:V398	4.47	No	No	0	9	9
341	R:R:L176	R:R:T401	2.95	No	Yes	8	9	7
342	R:R:C178	R:R:R180	5.57	No	No	11	8	9
343	R:R:C178	R:R:V181	3.42	No	Yes	11	8	9
344	R:R:Q179	R:R:Y243	9.02	Yes	Yes	12	7	8
345	R:R:K256	R:R:Q179	4.07	No	Yes	0	5	7
346	R:R:Q179	R:R:Q257	3.84	Yes	Yes	12	7	5
347	R:R:L259	R:R:Q179	6.65	Yes	Yes	0	5	7
348	R:R:R180	R:R:V181	3.92	No	Yes	11	9	9
349	R:R:H184	R:R:R180	6.77	No	No	0	9	9
350	R:R:K185	R:R:V181	3.04	No	Yes	11	6	9
351	R:R:L183	R:R:Y243	7.03	No	Yes	0	8	8
352	R:R:L183	R:R:L259	4.15	No	Yes	0	8	5
353	R:R:E240	R:R:H184	8.62	No	No	0	9	9
354	R:R:N186	R:R:W236	13.56	No	Yes	3	9	9
355	R:R:N186	R:R:Y263	9.3	No	No	3	9	5
356	R:R:M187	R:R:T190	3.01	Yes	Yes	3	8	9
357	R:R:M187	R:R:Y191	8.38	Yes	Yes	3	8	8
358	R:R:M187	R:R:M237	2.89	Yes	Yes	3	8	9
359	R:R:E240	R:R:M187	8.12	No	Yes	3	9	8
360	R:R:L351	R:R:M187	2.83	Yes	Yes	3	9	8
361	R:R:F188	R:R:V387	5.24	Yes	No	0	8	9
362	R:R:L189	R:R:L193	5.54	No	No	0	3	6
363	R:R:N233	R:R:T190	8.77	No	Yes	3	9	9
364	R:R:T190	R:R:W236	4.85	Yes	Yes	3	9	9
365	R:R:T190	R:R:W267	3.64	Yes	No	3	9	9
366	R:R:N233	R:R:Y191	15.12	No	Yes	3	9	8
367	R:R:M237	R:R:Y191	5.99	Yes	Yes	3	9	8
368	R:R:Q383	R:R:Y191	14.65	Yes	Yes	3	9	8
369	R:R:G384	R:R:Y191	7.24	No	Yes	0	9	8
370	R:R:V387	R:R:Y191	3.79	No	Yes	0	9	8
371	R:R:L193	R:R:M229	7.07	No	No	0	6	4
372	R:R:I198	R:R:N194	5.66	Yes	No	0	7	8
373	R:R:M230	R:R:N194	2.8	Yes	No	0	6	8
374	R:R:H226	R:R:I197	5.3	No	No	0	6	5
375	R:R:I197	R:R:M229	2.92	No	No	0	5	4
376	R:R:I198	R:R:L202	2.85	Yes	Yes	0	7	7
377	R:R:H226	R:R:I198	3.98	No	Yes	0	6	7
378	R:R:E204	R:R:I200	2.73	No	No	0	4	6
379	R:R:H201	R:R:V205	11.07	Yes	No	0	6	7
380	R:R:H201	R:R:V206	2.77	Yes	No	0	6	3
381	R:R:L202	R:R:V206	2.98	Yes	No	0	7	3
382	R:R:E204	R:R:V203	4.28	No	No	0	4	3
383	R:R:P207	R:R:V206	5.3	No	No	0	3	3
384	R:R:E210	R:R:N208	5.26	No	No	0	3	3
385	R:R:L211	R:R:N208	8.24	No	No	0	1	3
386	R:R:E210	R:R:R213	3.49	No	No	0	3	2
387	R:R:E210	R:R:R214	15.12	No	No	0	3	4
388	R:R:L211	R:R:R214	3.64	No	No	0	1	4
389	R:R:L211	R:R:P216	3.28	No	No	0	1	4
390	R:R:C289	R:R:V212	6.83	No	Yes	16	9	3
391	R:R:L291	R:R:V212	2.98	Yes	Yes	16	6	3
392	R:R:D215	R:R:K220	8.3	No	No	0	6	7
393	R:R:P216	R:R:S218	3.56	No	No	0	4	3
394	R:R:I221	R:R:V217	3.07	No	No	0	4	3
395	R:R:C219	R:R:C289	7.28	No	No	0	9	9
396	R:R:K220	R:R:N286	4.2	No	No	2	7	7
397	R:R:K220	R:R:W290	18.57	No	Yes	2	7	9
398	R:R:F225	R:R:I221	3.77	No	No	0	5	4
399	R:R:H223	R:R:Q227	13.6	No	Yes	0	5	7
400	R:R:H223	R:R:W290	10.58	No	Yes	0	5	9
401	R:R:F224	R:R:F225	4.29	Yes	No	0	5	5
402	R:R:F224	R:R:T274	5.19	Yes	No	0	5	6
403	R:R:A278	R:R:F224	2.77	No	Yes	0	6	5
404	R:R:M230	R:R:Q227	2.72	Yes	Yes	2	6	7
405	R:R:H277	R:R:Q227	9.89	Yes	Yes	2	7	7
406	R:R:I301	R:R:Q227	6.86	Yes	Yes	2	7	7
407	R:R:M229	R:R:Y228	5.99	No	No	0	4	8
408	R:R:C232	R:R:Y228	9.41	No	No	0	8	8
409	R:R:L271	R:R:Y228	4.69	No	No	0	4	8
410	R:R:M230	R:R:Y234	4.79	Yes	Yes	0	6	7
411	R:R:H302	R:R:M230	7.88	Yes	Yes	2	6	6
412	R:R:C232	R:R:W267	5.22	No	No	0	8	9
413	R:R:C232	R:R:P270	5.65	No	Yes	0	8	9
414	R:R:M237	R:R:N233	2.8	Yes	No	3	9	9
415	R:R:M237	R:R:Y234	3.59	Yes	Yes	0	9	7
416	R:R:V305	R:R:Y234	7.57	No	Yes	0	7	7
417	R:R:F356	R:R:Y234	11.35	Yes	Yes	0	7	7
418	R:R:F235	R:R:F269	8.57	Yes	Yes	6	5	3
419	R:R:F235	R:R:P270	5.78	Yes	Yes	6	5	9
420	R:R:A308	R:R:F235	2.77	No	Yes	0	7	5
421	R:R:C239	R:R:W236	7.84	No	Yes	0	7	9
422	R:R:W236	R:R:Y263	3.86	Yes	No	3	9	5
423	R:R:G266	R:R:W236	8.44	No	Yes	0	9	9
424	R:R:W236	R:R:W267	14.99	Yes	No	3	9	9
425	R:R:M237	R:R:Q383	5.44	Yes	Yes	3	9	9
426	R:R:I242	R:R:L238	7.14	Yes	Yes	0	7	8
427	R:R:L238	R:R:L265	2.77	Yes	Yes	0	8	7
428	R:R:A308	R:R:L238	3.15	No	Yes	0	7	8
429	R:R:L238	R:R:V311	2.98	Yes	No	0	8	6
430	R:R:L238	R:R:N312	5.49	Yes	No	0	8	9
431	R:R:C239	R:R:Y262	5.38	No	Yes	0	7	7
432	R:R:C239	R:R:L265	4.76	No	Yes	0	7	7
433	R:R:E240	R:R:L351	10.6	No	Yes	3	9	9
434	R:R:I242	R:R:Y262	4.84	Yes	Yes	0	7	7
435	R:R:F315	R:R:I242	3.77	No	Yes	0	8	7
436	R:R:L247	R:R:Y243	8.21	No	Yes	12	8	8
437	R:R:Q257	R:R:Y243	6.76	Yes	Yes	12	5	8
438	R:R:Y243	R:R:Y262	5.96	Yes	Yes	12	8	7
439	R:R:I319	R:R:L244	4.28	No	No	0	9	9
440	R:R:L244	R:R:L348	2.77	No	No	0	9	9
441	R:R:H245	R:R:V249	13.84	Yes	No	17	8	6
442	R:R:H245	R:R:V250	2.77	Yes	No	0	8	5
443	R:R:F315	R:R:H245	23.76	No	Yes	0	8	8
444	R:R:H245	R:R:N318	11.48	Yes	No	17	8	8
445	R:R:Q257	R:R:T246	4.25	Yes	No	0	5	7
446	R:R:L247	R:R:Q257	3.99	No	Yes	12	8	5
447	R:R:I248	R:R:V249	3.07	No	No	0	7	6
448	R:R:I248	R:R:V322	3.07	No	No	0	7	8
449	R:R:N318	R:R:V249	8.87	No	No	17	8	6
450	R:R:Q257	R:R:T254	4.25	Yes	No	0	5	6
451	R:R:E255	R:R:K256	4.05	No	No	0	6	5
452	R:R:Q257	R:R:Y262	4.51	Yes	Yes	12	5	7
453	R:R:R258	R:R:R260	10.66	Yes	No	10	5	3
454	R:R:R258	R:R:W261	11	Yes	Yes	10	5	2
455	R:R:L259	R:R:Y263	8.21	Yes	No	0	5	5
456	R:R:R260	R:R:W261	3	No	Yes	10	3	2
457	R:R:F269	R:R:L265	3.65	Yes	Yes	0	3	7
458	R:R:F269	R:R:P270	4.33	Yes	Yes	6	3	9
459	R:R:P273	R:R:V272	5.3	No	No	0	6	4
460	R:R:I301	R:R:T274	6.08	Yes	No	0	7	6
461	R:R:I276	R:R:I300	4.42	No	Yes	0	5	8
462	R:R:H277	R:R:R281	11.28	Yes	Yes	2	7	7
463	R:R:H277	R:R:L298	3.86	Yes	No	0	7	6
464	R:R:H277	R:R:I300	3.98	Yes	Yes	0	7	8
465	R:R:H277	R:R:I301	7.95	Yes	Yes	2	7	7
466	R:R:L297	R:R:T280	11.79	Yes	No	0	4	4
467	R:R:I300	R:R:T280	4.56	Yes	No	0	8	4
468	R:R:F285	R:R:R281	7.48	Yes	Yes	2	6	7
469	R:R:D287	R:R:R281	3.57	No	Yes	2	3	7
470	R:R:R281	R:R:W290	13	Yes	Yes	2	7	9
471	R:R:R281	R:R:T295	5.17	Yes	Yes	2	7	4
472	R:R:L297	R:R:R281	4.86	Yes	Yes	2	4	7
473	R:R:V283	R:R:Y284	8.83	No	No	0	3	2
474	R:R:D287	R:R:F285	3.58	No	Yes	2	3	6
475	R:R:F285	R:R:S292	6.61	Yes	No	2	6	4
476	R:R:F285	R:R:T295	20.75	Yes	Yes	2	6	4
477	R:R:N286	R:R:W290	3.39	No	Yes	2	7	9
478	R:R:D287	R:R:S292	5.89	No	No	2	3	4
479	R:R:C289	R:R:L291	4.76	No	Yes	16	9	6
480	R:R:E294	R:R:S292	2.87	No	No	0	3	4
481	R:R:E294	R:R:V293	2.85	No	No	0	3	6
482	R:R:L298	R:R:V293	2.98	No	No	0	6	6
483	R:R:L297	R:R:T295	4.42	Yes	Yes	2	4	4
484	R:R:G303	R:R:P304	4.06	No	No	6	4	9
485	R:R:F356	R:R:L309	3.65	Yes	No	0	7	7
486	R:R:F314	R:R:V310	5.24	No	No	0	5	4
487	R:R:F315	R:R:V311	5.24	No	No	0	8	6
488	R:R:L352	R:R:N312	8.24	Yes	No	0	9	9
489	R:R:F313	R:R:L317	7.31	Yes	No	0	6	5
490	R:R:F313	R:R:V357	5.24	Yes	No	0	6	7
491	R:R:L316	R:R:V320	2.98	No	No	0	9	7
492	R:R:L316	R:R:L348	4.15	No	No	0	9	9
493	R:R:I354	R:R:L316	7.14	Yes	No	0	6	9
494	R:R:N318	R:R:R321	8.44	No	No	0	8	8
495	R:R:T345	R:R:V320	3.17	No	No	0	9	7
496	R:R:K326	R:R:V322	3.04	No	No	0	9	8
497	R:R:R328	R:R:V324	6.54	No	No	0	6	5
498	R:R:E332	R:R:M327	2.71	No	Yes	0	5	7
499	R:R:M327	R:R:M337	5.78	Yes	Yes	0	7	7
500	R:R:K340	R:R:M327	2.88	No	Yes	0	8	7
501	R:R:E332	R:R:T330	8.47	No	No	0	5	5
502	R:R:H336	R:R:S335	5.58	No	No	0	6	6
503	R:R:M337	R:R:Y338	4.79	Yes	No	0	7	7
504	R:R:K340	R:R:K343	2.87	No	No	0	8	8
505	R:R:M346	R:R:V342	4.56	No	No	0	8	8
506	R:R:I347	R:R:I390	5.89	No	No	3	8	8
507	R:R:I347	R:R:Y391	6.04	No	Yes	3	8	8
508	R:R:L348	R:R:Y391	3.52	No	Yes	0	9	8
509	R:R:P350	R:R:V349	5.3	No	No	0	9	8
510	R:R:I354	R:R:V349	7.68	Yes	No	0	6	8
511	R:R:Q355	R:R:V349	2.87	Yes	No	0	8	8
512	R:R:F386	R:R:P350	4.33	No	No	0	5	9
513	R:R:L351	R:R:L352	2.77	Yes	Yes	0	9	9
514	R:R:L351	R:R:Y391	11.72	Yes	Yes	3	9	8
515	R:R:I354	R:R:L352	4.28	Yes	Yes	0	6	9
516	R:R:G353	R:R:Q355	4.93	No	Yes	3	9	8
517	R:R:F356	R:R:G353	3.01	Yes	No	3	7	9
518	R:R:F356	R:R:Q355	9.37	Yes	Yes	3	7	8
519	R:R:Q355	R:R:Q383	8.96	Yes	Yes	3	8	9
520	R:R:F356	R:R:I380	7.54	Yes	No	0	7	6
521	R:R:F356	R:R:Q383	4.68	Yes	Yes	3	7	9
522	R:R:F359	R:R:V358	7.87	No	No	0	6	5
523	R:R:F359	R:R:Y372	4.13	No	Yes	9	6	7
524	R:R:F359	R:R:M376	3.73	No	No	9	6	7
525	R:R:P363	R:R:R362	2.88	Yes	Yes	9	7	4
526	R:R:G369	R:R:R362	6	No	Yes	9	4	4
527	R:R:R362	R:R:Y372	7.2	Yes	Yes	9	4	7
528	R:R:D373	R:R:R362	13.1	No	Yes	0	5	4
529	R:R:L368	R:R:P363	3.28	No	Yes	0	3	7
530	R:R:G369	R:R:P363	4.06	No	Yes	9	4	7
531	R:R:P363	R:R:Y372	9.74	Yes	Yes	9	7	7
532	R:R:M367	R:R:N365	2.8	No	No	0	4	4
533	R:R:L368	R:R:N365	8.24	No	No	0	3	4
534	R:R:K370	R:R:M367	2.88	No	No	0	4	4
535	R:R:K370	R:R:Y374	3.58	No	Yes	7	4	6
536	R:R:M376	R:R:Y372	14.37	No	Yes	9	7	7
537	R:R:L379	R:R:V375	2.98	No	No	0	5	4
538	R:R:I380	R:R:M376	2.92	No	No	0	6	7
539	R:R:H377	R:R:H381	9.55	Yes	No	0	7	9
540	R:R:F382	R:R:F386	3.22	No	No	0	7	5
541	R:R:F385	R:R:F386	4.29	Yes	No	0	5	5
542	R:R:F385	R:R:T389	7.78	Yes	No	0	5	5
543	R:R:V387	R:R:Y391	5.05	No	Yes	0	9	8
544	R:R:F393	R:R:T389	6.49	Yes	No	0	8	5
545	R:R:I390	R:R:Y391	3.63	No	Yes	3	8	8
546	R:R:C392	R:R:F393	2.79	No	Yes	0	9	8
547	R:R:E397	R:R:N395	15.77	No	No	0	9	9
548	R:R:N395	R:R:V398	7.39	No	No	0	9	9
549	R:R:N396	R:R:T400	2.92	No	No	0	6	4
550	R:R:R404	R:R:T401	3.88	No	Yes	0	7	7
551	R:R:F409	R:R:Q405	3.51	No	No	0	3	4
552	R:R:F409	R:R:W406	3.01	No	No	0	3	6
553	L:L:C2	R:R:Y299	2.69	Yes	No	0	0	7
554	R:R:A51	R:R:Y98	2.67	No	Yes	0	8	4
555	R:R:L379	R:R:Q355	2.66	No	Yes	0	5	8
556	E:E:N31	E:E:Q28	2.64	No	No	0	2	4
557	E:E:F44	E:E:S65	2.64	Yes	No	1	9	4
558	E:E:R102	E:E:S103	2.64	No	No	0	5	7
559	E:E:V129	R:R:F269	2.62	No	Yes	0	7	3
560	L:L:V32	R:R:F102	2.62	No	Yes	0	0	4
561	R:R:F170	R:R:V398	2.62	Yes	No	0	8	9
562	R:R:F173	R:R:V402	2.62	Yes	No	0	7	5
563	R:R:H201	R:R:L291	2.57	Yes	Yes	0	6	6
564	R:R:V203	R:R:Y149	2.52	No	Yes	0	3	5
565	E:E:F122	E:E:I118	2.51	No	No	0	9	7
566	R:R:F313	R:R:I354	2.51	Yes	Yes	0	6	6
567	R:R:M337	R:R:R328	2.48	Yes	No	0	7	6
568	E:E:V137	R:R:W261	2.45	No	Yes	0	9	2
569	L:L:T4	R:R:W361	2.43	Yes	No	0	0	4
570	E:E:I123	R:R:Y299	2.42	No	No	0	9	7
571	R:R:K47	R:R:Y98	2.39	No	Yes	0	4	4
572	H:H:?4	R:R:F119	2.19	Yes	No	0	0	4
573	R:R:F313	R:R:F314	2.14	Yes	No	0	6	5
574	L:L:G20	L:L:G21	2.11	No	No	0	0	0
575	E:E:G116	E:E:P115	2.03	No	No	0	5	9
576	R:R:G268	R:R:P270	2.03	No	Yes	0	6	9
577	R:R:C178	R:R:G177	1.96	No	No	0	8	7
578	E:E:C104	E:E:P105	1.88	No	No	0	9	7
579	R:R:C219	R:R:P216	1.88	No	No	0	9	4
580	R:R:A231	R:R:P270	1.87	No	Yes	0	5	9
581	L:L:G14	L:L:S17	1.86	No	No	0	0	0
582	R:R:G209	R:R:V212	1.84	No	Yes	0	3	3
583	L:L:V22	R:R:P100	1.77	No	No	0	0	4
584	R:R:G116	R:R:K115	1.74	No	No	0	9	5
585	R:R:G241	R:R:L352	1.71	No	Yes	0	8	9
586	R:R:G268	R:R:L264	1.71	No	No	0	6	3
587	R:R:A333	R:R:S335	1.71	No	No	0	5	6
588	E:E:A110	E:E:V111	1.7	No	No	0	4	5
589	L:L:G33	L:L:N31	1.7	No	No	0	0	0
590	R:R:A251	R:R:V250	1.7	No	No	0	6	5
591	R:R:I301	R:R:P273	1.69	Yes	No	0	7	6
592	R:R:C394	R:R:T389	1.69	No	No	0	5	5
593	R:R:M306	R:R:P360	1.68	No	No	0	4	5
594	E:E:G98	R:R:Q60	1.64	No	No	0	5	3
595	R:R:E68	R:R:G67	1.64	No	No	0	1	2
596	E:E:C40	E:E:M76	1.62	No	No	0	9	4
597	E:E:I127	R:R:A307	1.62	No	No	0	8	3
598	L:L:P29	R:R:D101	1.61	No	Yes	0	0	4
599	R:R:V320	R:R:V324	1.6	No	No	0	7	5
600	E:E:T128	E:E:V124	1.59	No	No	0	5	6
601	E:E:L131	R:R:A307	1.58	No	No	0	8	3
602	R:R:A344	R:R:L323	1.58	No	No	0	9	9
603	R:R:T400	R:R:T401	1.57	No	Yes	0	4	7
604	E:E:A87	E:E:N86	1.56	No	Yes	0	4	9
605	R:R:I160	R:R:V164	1.54	No	No	0	5	4
606	R:R:I192	R:R:V164	1.54	No	No	0	7	4
607	R:R:I371	R:R:V375	1.54	No	No	0	5	4
608	R:R:K115	R:R:V117	1.52	No	No	0	5	5
609	R:R:K120	R:R:V117	1.52	No	No	0	1	5
610	R:R:I279	R:R:T275	1.52	No	No	0	3	3
611	R:R:A407	R:R:Q408	1.52	No	No	0	4	7
612	E:E:A34	E:E:E38	1.51	No	No	0	2	4
613	E:E:A50	E:E:E49	1.51	No	No	0	5	3
614	R:R:L222	R:R:V205	1.49	No	No	0	6	7
615	R:R:N288	R:R:V212	1.48	No	Yes	0	4	3
616	R:R:L142	R:R:T138	1.47	Yes	No	0	2	2
617	R:R:L259	R:R:T182	1.47	Yes	No	0	5	5
618	R:R:D113	R:R:V117	1.46	No	No	0	5	5
619	R:R:I160	R:R:M196	1.46	No	No	0	5	4
620	R:R:I192	R:R:M196	1.46	No	No	0	7	4
621	R:R:D83	R:R:T85	1.45	No	Yes	0	5	7
622	E:E:G52	E:E:W56	1.41	No	Yes	0	5	5
623	R:R:L323	R:R:M327	1.41	No	Yes	0	9	7
624	R:R:E329	R:R:T325	1.41	No	No	0	6	7
625	E:E:P121	E:E:Y120	1.39	No	No	0	7	5
626	R:R:K403	R:R:Q399	1.36	No	No	0	6	7
627	R:R:E140	R:R:K143	1.35	No	No	0	2	1
628	R:R:E334	R:R:M337	1.35	No	Yes	0	6	7
629	E:E:E38	E:E:L35	1.33	No	Yes	14	4	2
630	E:E:E38	E:E:L39	1.33	No	No	14	4	1
631	R:R:R45	R:R:V42	1.31	Yes	No	0	7	1
632	R:R:F224	R:R:T275	1.3	Yes	No	0	5	3
633	R:R:A282	R:R:W290	1.3	No	Yes	0	3	9
634	E:E:L136	E:E:W139	1.14	No	No	0	7	6
635	R:R:E114	R:R:Y111	1.12	No	No	0	2	4

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	E:E:Y32	5.9875	4	1	5
2	E:E:L35	3.4475	4	14	2
3	E:E:F44	5.6	5	1	9
4	E:E:D47	5.0925	4	1	5
5	E:E:M48	7.538	5	1	9
6	E:E:W56	8.805	4	1	5
7	E:E:W59	9.4925	4	1	7
8	E:E:Y66	6.735	4	1	9
9	E:E:W84	7.87167	6	1	7
10	E:E:N86	5.8875	4	1	9
11	E:E:E88	6.0825	4	1	4
12	E:E:F92	7.0975	4	0	5
13	E:E:F93	10.0075	4	1	9
14	E:E:H97	9.018	5	1	9
15	E:E:Y100	9.03	5	1	8
16	E:E:F101	6.574	5	1	9
17	E:E:D113	5.41	4	2	9
18	E:E:P114	6.6825	4	0	9
19	E:E:Q140	10.9325	4	10	8
20	H:H:?1	6.086	5	5	0
21	H:H:?4	11.3225	4	1	0
22	L:L:C2	4.506	5	2	0
23	L:L:T4	3.684	5	2	0
24	L:L:T6	7.2625	4	2	0
25	L:L:T30	9.3825	4	1	0
26	L:L:?37	5.84222	9	1	0
27	L:L:?101	7.80333	6	5	0
28	R:R:R45	3.5575	4	1	7
29	R:R:M49	4.342	5	1	4
30	R:R:Q52	6.65167	6	1	6
31	R:R:Y53	12.22	5	1	1
32	R:R:Y56	7.97714	7	1	3
33	R:R:M59	5.25	4	1	5
34	R:R:Y65	8.41	4	4	3
35	R:R:W76	7.27	6	1	8
36	R:R:D77	4.97	6	1	9
37	R:R:W79	9.36167	6	1	6
38	R:R:L80	5.976	5	1	5
39	R:R:T85	4.43333	6	4	7
40	R:R:P86	6.4875	4	4	2
41	R:R:P96	8.015	4	1	9
42	R:R:Y98	6.23833	6	1	4
43	R:R:F99	9.86	5	1	5
44	R:R:D101	6.152	5	1	4
45	R:R:F102	6.3	8	1	4
46	R:R:D103	6.135	4	1	3
47	R:R:E106	4.255	4	1	4
48	R:R:T109	4.515	4	1	5
49	R:R:K110	12.13	4	0	8
50	R:R:W118	9.228	5	4	9
51	R:R:W128	10.14	4	1	5
52	R:R:S129	6.575	4	1	7
53	R:R:N130	10.128	5	1	8
54	R:R:Y131	8.31333	6	1	5
55	R:R:M133	4.735	4	1	5
56	R:R:L142	4.025	4	15	2
57	R:R:L148	7.7225	4	7	5
58	R:R:Y149	6.22	5	5	5
59	R:R:Y150	8.3375	4	5	4
60	R:R:F170	5.834	5	11	8
61	R:R:F173	6.398	5	8	7
62	R:R:Q179	5.895	4	12	7
63	R:R:V181	5.2175	4	11	9
64	R:R:M187	5.046	5	3	8
65	R:R:F188	5.1875	4	0	8
66	R:R:T190	5.0675	4	3	9
67	R:R:Y191	9.195	6	3	8
68	R:R:I198	5.492	5	0	7
69	R:R:H201	4.835	4	0	6
70	R:R:L202	3.3425	4	5	7
71	R:R:V212	3.2825	4	16	3
72	R:R:F224	3.3875	4	0	5
73	R:R:Q227	8.2675	4	2	7
74	R:R:M230	4.952	5	2	6
75	R:R:Y234	7.208	5	0	7
76	R:R:F235	5.2525	4	6	5
77	R:R:W236	8.92333	6	3	9
78	R:R:M237	4.142	5	3	9
79	R:R:L238	4.81667	6	0	8
80	R:R:I242	5.3	5	0	7
81	R:R:Y243	7.396	5	12	8
82	R:R:H245	12.9625	4	17	8
83	R:R:Q257	4.6	6	12	5
84	R:R:R258	10.7075	4	10	5
85	R:R:L259	5.12	4	0	5
86	R:R:W261	8.22	4	10	2
87	R:R:Y262	5.1725	4	12	7
88	R:R:L265	4.6575	4	0	7
89	R:R:F269	6.24333	6	6	3
90	R:R:P270	3.932	5	6	9
91	R:R:H277	7.392	5	2	7
92	R:R:R281	7.56	6	2	7
93	R:R:F285	8.92833	6	2	6
94	R:R:W290	9.368	5	2	9
95	R:R:L291	3.7025	4	16	6
96	R:R:T295	9.7525	4	2	4
97	R:R:L297	6.5	4	2	4
98	R:R:I300	4.0875	4	0	8
99	R:R:I301	5.645	4	2	7
100	R:R:H302	8.112	5	2	6
101	R:R:F313	4.3	4	0	6
102	R:R:M327	3.195	4	0	7
103	R:R:M337	3.6	4	0	7
104	R:R:L351	6.98	4	3	9
105	R:R:L352	4.25	4	0	9
106	R:R:I354	5.4025	4	0	6
107	R:R:Q355	5.758	5	3	8
108	R:R:F356	6.25143	7	3	7
109	R:R:R362	7.295	4	9	4
110	R:R:P363	4.99	4	9	7
111	R:R:Y372	8.86	4	9	7
112	R:R:Y374	4.4925	4	7	6
113	R:R:H377	10.225	4	7	7
114	R:R:Q383	8.4325	4	3	9
115	R:R:F385	6.79	4	0	5
116	R:R:Y391	5.992	5	3	8
117	R:R:F393	4.235	4	0	8
118	R:R:T401	3.098	5	8	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	E:E:N86	E:E:Y32	11.1515	12.79	Yes	Yes	1	9	5
2	E:E:V89	E:E:Y32	14.4061	3.79	No	Yes	1	8	5
3	E:E:F44	E:E:L69	10.3081	14.61	Yes	No	0	9	8
4	E:E:V89	E:E:W84	14.5022	6.13	No	Yes	1	8	7
5	E:E:W84	R:R:Q52	37.3855	4.38	Yes	Yes	1	7	6
6	E:E:F93	R:R:Q52	18.6135	9.37	Yes	Yes	1	9	6
7	E:E:F93	E:E:L69	10.8704	4.87	Yes	No	0	9	8
8	R:R:Q52	R:R:Y56	10.2925	5.64	Yes	Yes	1	6	3
9	E:E:W84	L:L:?37	60.0738	3.69	Yes	Yes	1	7	0
10	L:L:?37	R:R:W128	93.0651	6.46	Yes	Yes	1	0	5
11	H:H:?4	R:R:W128	47.5466	7.15	Yes	Yes	1	0	5
12	H:H:?4	R:R:M133	47.896	7.61	Yes	Yes	1	0	5
13	R:R:E106	R:R:M133	99.3145	2.71	Yes	Yes	1	4	5
14	R:R:D103	R:R:E106	99.3064	6.5	Yes	Yes	1	3	4
15	R:R:D103	R:R:K141	99.7125	2.77	Yes	No	0	3	3
16	L:L:L15	R:R:K141	99.757	4.23	No	No	0	0	3
17	L:L:L15	R:R:L142	99.5806	4.15	No	Yes	15	0	2
18	L:L:V23	R:R:L142	99.9624	4.47	No	Yes	0	0	2
19	L:L:V23	R:R:Y146	100	10.09	No	No	0	0	2
20	R:R:Y146	R:R:Y150	56.047	3.97	No	Yes	5	2	4
21	R:R:Y149	R:R:Y150	56.3159	11.91	Yes	Yes	5	5	4
22	R:R:L202	R:R:Y149	48.4797	4.69	Yes	Yes	5	7	5
23	R:R:I198	R:R:L202	50.7006	2.85	Yes	Yes	0	7	7
24	R:R:I198	R:R:N194	31.3287	5.66	Yes	No	0	7	8
25	R:R:M230	R:R:N194	31.2257	2.8	Yes	No	0	6	8
26	R:R:M230	R:R:Q227	21.9566	2.72	Yes	Yes	2	6	7
27	R:R:H277	R:R:Q227	13.8595	9.89	Yes	Yes	2	7	7
28	R:R:H277	R:R:R281	10.3677	11.28	Yes	Yes	2	7	7
29	R:R:N130	R:R:W128	48.8702	7.91	Yes	Yes	1	8	5
30	R:R:M133	R:R:N130	47.881	5.61	Yes	Yes	1	5	8
31	R:R:H226	R:R:I198	17.2604	3.98	No	Yes	0	6	7
32	R:R:H226	R:R:I197	13.3064	5.3	No	No	0	6	5
33	R:R:I197	R:R:M229	13.0108	2.92	No	No	0	5	4
34	R:R:M229	R:R:Y228	12.4919	5.99	No	No	0	4	8
35	R:R:C232	R:R:Y228	12.3195	9.41	No	No	0	8	8
36	R:R:C232	R:R:P270	11.6467	5.65	No	Yes	0	8	9
37	L:L:?101	R:R:Y146	43.9889	11.3	Yes	No	5	0	2
38	L:L:?101	R:R:L151	44.2365	3.64	Yes	No	0	0	5
39	R:R:F382	R:R:L151	43.8119	3.65	No	No	0	7	5
40	R:R:F382	R:R:F386	43.6499	3.22	No	No	0	7	5
41	R:R:F386	R:R:P350	28.2303	4.33	No	No	0	5	9
42	R:R:P350	R:R:V349	28.1111	5.3	No	No	0	9	8
43	R:R:I354	R:R:V349	27.2174	7.68	Yes	No	0	6	8
44	R:R:I354	R:R:L352	20.456	4.28	Yes	Yes	0	6	9
45	R:R:L352	R:R:N312	22.1579	8.24	Yes	No	0	9	9
46	R:R:L238	R:R:N312	21.8386	5.49	Yes	No	0	8	9
47	R:R:I242	R:R:L238	12.4288	7.14	Yes	Yes	0	7	8
48	R:R:F315	R:R:H245	11.0775	23.76	No	Yes	0	8	8
49	R:R:M230	R:R:Y234	23.9726	4.79	Yes	Yes	0	6	7
50	R:R:L202	R:R:V206	12.9854	2.98	Yes	No	0	7	3
51	R:R:H201	R:R:V206	11.8804	2.77	Yes	No	0	6	3
52	L:L:?37	R:R:W79	14.4478	9.23	Yes	Yes	1	0	6
53	L:L:?37	R:R:S129	11.1562	6.08	Yes	Yes	1	0	7
54	R:R:K110	R:R:S129	10.8698	10.71	Yes	Yes	0	8	7
55	R:R:F385	R:R:F386	17.8262	4.29	Yes	No	0	5	5
56	R:R:M237	R:R:Y234	23.2917	3.59	Yes	Yes	0	9	7
57	R:R:C392	R:R:F393	13.2648	2.79	No	Yes	0	9	8
58	R:R:C392	R:R:F170	12.3658	6.98	No	Yes	0	9	8
59	R:R:F170	R:R:V398	12.0875	2.62	Yes	No	0	8	9
60	R:R:M187	R:R:M237	12.6834	2.89	Yes	Yes	3	8	9
61	R:R:M187	R:R:T190	12.3305	3.01	Yes	Yes	3	8	9
62	R:R:T190	R:R:W236	18.1027	4.85	Yes	Yes	3	9	9
63	R:R:N233	R:R:T190	11.4871	8.77	No	Yes	3	9	9
64	R:R:C239	R:R:W236	10.6216	7.84	No	Yes	0	7	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
E:E:T73	E:E:W84	8.49	1	No	Yes	9	7	2	1
E:E:T73	E:E:V89	7.93	1	No	No	9	8	2	2
E:E:W74	E:E:W84	5.62	0	No	Yes	6	7	2	1
E:E:F83	R:R:N124	9.67	0	No	No	5	5	2	1
E:E:F83	R:R:R126	23.52	0	No	No	5	4	2	1
E:E:P85	E:E:W84	18.92	0	No	Yes	9	7	2	1
E:E:V89	E:E:W84	6.13	1	No	Yes	8	7	2	1
E:E:W84	L:L:?37	3.69	1	Yes	Yes	7	0	1	0
E:E:W84	R:R:Q52	4.38	1	Yes	Yes	7	6	1	2
E:E:P85	R:R:G78	4.06	0	No	No	9	5	2	1
H:H:?1	L:L:K24	3.71	5	Yes	No	0	0	1	0
H:H:?1	L:L:?101	5.32	5	Yes	Yes	0	0	1	0
H:H:?1	R:R:Y150	7.19	5	Yes	Yes	0	4	1	1
H:H:?1	R:R:I153	5	5	Yes	No	0	7	1	2
H:H:?1	R:R:S157	9.21	5	Yes	No	0	7	1	2
H:H:?4	R:R:W128	7.15	1	Yes	Yes	0	5	2	1
H:H:?4	R:R:N130	28.34	1	Yes	Yes	0	8	2	2
L:L:A1	R:R:E294	4.53	0	No	No	0	3	0	1
L:L:C2	R:R:L298	4.76	2	Yes	No	0	6	0	1
L:L:C2	R:R:H302	4.42	2	Yes	Yes	0	6	0	1
L:L:D3	R:R:W361	10.05	0	No	No	0	4	0	1
L:L:T4	R:R:M306	4.52	2	Yes	No	0	4	0	1
L:L:A5	R:R:F356	4.16	0	No	Yes	0	7	0	1
L:L:T6	R:R:Y234	8.74	2	Yes	Yes	0	7	0	1
L:L:T6	R:R:H302	9.58	2	Yes	Yes	0	6	0	1
L:L:T6	R:R:M306	6.02	2	Yes	No	0	4	0	1
L:L:C7	R:R:H302	10.32	2	No	Yes	0	6	0	1
L:L:V8	R:R:H377	6.92	0	No	Yes	0	7	0	1
L:L:V8	R:R:I380	4.61	0	No	No	0	6	0	1
L:L:T9	R:R:I198	3.04	0	No	Yes	0	7	0	1
L:L:H10	R:R:H226	7.17	2	No	No	0	6	0	1
L:L:H10	R:R:M230	6.57	2	No	Yes	0	6	0	1
L:L:H10	R:R:H302	8.36	2	No	Yes	0	6	0	1
L:L:R11	R:R:V293	3.92	0	No	No	0	6	0	1
L:L:L12	R:R:L148	2.77	7	No	Yes	0	5	0	1
L:L:L12	R:R:H377	6.43	7	No	Yes	0	7	0	1
L:L:A13	R:R:H201	2.93	0	No	Yes	0	6	0	1
L:L:L15	R:R:K141	4.23	15	No	No	0	3	0	1
L:L:L15	R:R:L142	4.15	15	No	Yes	0	2	0	1
L:L:L16	R:R:A145	3.15	0	No	No	0	4	0	1
L:L:L16	R:R:Y149	3.52	0	No	Yes	0	5	0	1
L:L:S17	R:R:L291	4.5	0	No	Yes	0	6	0	1
L:L:R18	R:R:P104	5.76	0	No	No	0	3	0	1
L:L:S19	R:R:L142	6.01	15	No	Yes	0	2	0	1
L:L:V23	R:R:L142	4.47	0	No	Yes	0	2	0	1
L:L:V23	R:R:Y146	10.09	0	No	No	0	2	0	1
L:L:F27	R:R:D101	4.78	0	No	Yes	0	4	0	1
L:L:T30	R:R:F99	20.75	1	Yes	Yes	0	5	0	1
L:L:T30	R:R:D101	8.67	1	Yes	Yes	0	4	0	1
L:L:T30	R:R:F102	5.19	1	Yes	Yes	0	4	0	1
L:L:T30	R:R:N135	2.92	1	Yes	No	0	3	0	1
L:L:S34	R:R:H121	6.97	0	No	No	0	4	0	1
L:L:S34	R:R:E123	10.06	0	No	No	0	4	0	1
L:L:K35	R:R:N124	4.2	0	No	No	0	5	0	1
L:L:?37	R:R:D77	3.3	1	Yes	Yes	0	9	0	1
L:L:?37	R:R:G78	8.32	1	Yes	No	0	5	0	1
L:L:?37	R:R:W79	9.23	1	Yes	Yes	0	6	0	1
L:L:?37	R:R:R126	7.87	1	Yes	No	0	4	0	1
L:L:?37	R:R:W128	6.46	1	Yes	Yes	0	5	0	1
L:L:?37	R:R:S129	6.08	1	Yes	Yes	0	7	0	1
L:L:?37	R:R:Y131	3.8	1	Yes	Yes	0	5	0	1
L:L:?101	R:R:Y146	11.3	5	Yes	No	0	2	0	1
L:L:?101	R:R:Y150	10.28	5	Yes	Yes	0	4	0	1
L:L:?101	R:R:L151	3.64	5	Yes	No	0	5	0	1
L:L:?101	R:R:V154	3.92	5	Yes	No	0	6	0	1
R:R:M48	R:R:W79	5.82	1	No	Yes	6	6	2	1
R:R:M48	R:R:Y98	9.58	1	No	Yes	6	4	2	2
R:R:D77	R:R:G78	3.35	1	Yes	No	9	5	1	1
R:R:D77	R:R:L80	4.07	1	Yes	Yes	9	5	1	2
R:R:D77	R:R:W82	8.93	1	Yes	No	9	9	1	2
R:R:D77	R:R:S129	4.42	1	Yes	Yes	9	7	1	1
R:R:D77	R:R:Y131	5.75	1	Yes	Yes	9	5	1	1
R:R:W79	R:R:Y98	5.79	1	Yes	Yes	6	4	1	2
R:R:F99	R:R:W79	9.02	1	Yes	Yes	5	6	1	1
R:R:F102	R:R:W79	7.02	1	Yes	Yes	4	6	1	1
R:R:W79	R:R:Y131	19.29	1	Yes	Yes	6	5	1	1
R:R:L80	R:R:P96	11.49	1	Yes	Yes	5	9	2	2
R:R:L80	R:R:V108	4.47	1	Yes	No	5	7	2	2
R:R:L80	R:R:Y131	5.86	1	Yes	Yes	5	5	2	1
R:R:K110	R:R:W82	19.73	0	Yes	No	8	9	2	2
R:R:C95	R:R:P96	3.77	1	No	Yes	9	9	2	2
R:R:C95	R:R:F102	6.98	1	No	Yes	9	4	2	1
R:R:C134	R:R:C95	7.28	1	No	No	9	9	2	2
R:R:P96	R:R:Y98	13.91	1	Yes	Yes	9	4	2	2
R:R:F102	R:R:P96	2.89	1	Yes	Yes	4	9	1	2
R:R:F99	R:R:Y98	3.09	1	Yes	Yes	5	4	1	2
R:R:D101	R:R:F99	3.58	1	Yes	Yes	4	5	1	1
R:R:F102	R:R:F99	12.86	1	Yes	Yes	4	5	1	1
R:R:D101	R:R:N135	12.12	1	Yes	No	4	3	1	1
R:R:C134	R:R:F102	5.59	1	No	Yes	9	4	2	1
R:R:F102	R:R:N135	7.25	1	Yes	No	4	3	1	1
R:R:D103	R:R:P104	6.44	1	Yes	No	3	3	2	1
R:R:D103	R:R:K141	2.77	1	Yes	No	3	3	2	1
R:R:V108	R:R:Y131	10.09	1	No	Yes	7	5	2	1
R:R:K110	R:R:S129	10.71	0	Yes	Yes	8	7	2	1
R:R:H121	R:R:P122	10.68	0	No	No	4	5	1	2
R:R:H121	R:R:W128	19.04	0	No	Yes	4	5	1	1
R:R:E123	R:R:N124	13.15	0	No	No	4	5	1	1
R:R:N130	R:R:W128	7.91	1	Yes	Yes	8	5	2	1
R:R:S129	R:R:Y131	5.09	1	Yes	Yes	7	5	1	1
R:R:Y146	R:R:Y150	3.97	5	No	Yes	2	4	1	1
R:R:D373	R:R:L148	5.43	0	No	Yes	5	5	2	1
R:R:L148	R:R:Y374	4.69	7	Yes	Yes	5	6	1	2
R:R:H377	R:R:L148	18	7	Yes	Yes	7	5	1	1
R:R:Y149	R:R:Y150	11.91	5	Yes	Yes	5	4	1	1
R:R:I153	R:R:Y149	8.46	5	No	Yes	7	5	2	1
R:R:L202	R:R:Y149	4.69	5	Yes	Yes	7	5	2	1
R:R:L151	R:R:S378	6.01	0	No	No	5	5	1	2
R:R:F382	R:R:L151	3.65	0	No	No	7	5	2	1
R:R:I153	R:R:L202	2.85	5	No	Yes	7	7	2	2
R:R:H156	R:R:I198	11.93	0	No	Yes	7	7	2	1
R:R:H156	R:R:H381	10.75	0	No	No	7	9	2	2
R:R:I198	R:R:N194	5.66	0	Yes	No	7	8	1	2
R:R:M230	R:R:N194	2.8	2	Yes	No	6	8	1	2
R:R:H226	R:R:I197	5.3	0	No	No	6	5	1	2
R:R:I198	R:R:L202	2.85	0	Yes	Yes	7	7	1	2
R:R:H226	R:R:I198	3.98	0	No	Yes	6	7	1	1
R:R:H201	R:R:V205	11.07	0	Yes	No	6	7	1	2
R:R:H201	R:R:V206	2.77	0	Yes	No	6	3	1	2
R:R:L202	R:R:V206	2.98	5	Yes	No	7	3	2	2
R:R:C289	R:R:V212	6.83	16	No	Yes	9	3	2	2
R:R:L291	R:R:V212	2.98	16	Yes	Yes	6	3	1	2
R:R:M230	R:R:Q227	2.72	2	Yes	Yes	6	7	1	2
R:R:H277	R:R:Q227	9.89	2	Yes	Yes	7	7	2	2
R:R:M230	R:R:Y234	4.79	2	Yes	Yes	6	7	1	1
R:R:H302	R:R:M230	7.88	2	Yes	Yes	6	6	1	1
R:R:M237	R:R:Y234	3.59	3	Yes	Yes	9	7	2	1
R:R:V305	R:R:Y234	7.57	0	No	Yes	7	7	2	1
R:R:F356	R:R:Y234	11.35	3	Yes	Yes	7	7	1	1
R:R:M237	R:R:Q383	5.44	3	Yes	Yes	9	9	2	2
R:R:H277	R:R:L298	3.86	2	Yes	No	7	6	2	1
R:R:C289	R:R:L291	4.76	16	No	Yes	9	6	2	1
R:R:E294	R:R:S292	2.87	0	No	No	3	4	1	2
R:R:E294	R:R:V293	2.85	0	No	No	3	6	1	1
R:R:L298	R:R:V293	2.98	0	No	No	6	6	1	1
R:R:F356	R:R:L309	3.65	3	Yes	No	7	7	1	2
R:R:G353	R:R:Q355	4.93	3	No	Yes	9	8	2	2
R:R:F356	R:R:G353	3.01	3	Yes	No	7	9	1	2
R:R:F356	R:R:Q355	9.37	3	Yes	Yes	7	8	1	2
R:R:Q355	R:R:Q383	8.96	3	Yes	Yes	8	9	2	2
R:R:F356	R:R:I380	7.54	3	Yes	No	7	6	1	1
R:R:F356	R:R:Q383	4.68	3	Yes	Yes	7	9	1	2
R:R:I380	R:R:M376	2.92	0	No	No	6	7	1	2
R:R:H377	R:R:H381	9.55	7	Yes	No	7	9	1	2
L:L:C2	R:R:Y299	2.69	2	Yes	No	0	7	0	1
L:L:V32	R:R:F102	2.62	0	No	Yes	0	4	0	1
R:R:H201	R:R:L291	2.57	0	Yes	Yes	6	6	1	1
R:R:V203	R:R:Y149	2.52	0	No	Yes	3	5	2	1
L:L:T4	R:R:W361	2.43	2	Yes	No	0	4	0	1
E:E:I123	R:R:Y299	2.42	0	No	No	9	7	2	1
L:L:V22	R:R:P100	1.77	0	No	No	0	4	0	1
R:R:M306	R:R:P360	1.68	2	No	No	4	5	1	2
L:L:P29	R:R:D101	1.61	0	No	Yes	0	4	0	1
R:R:L142	R:R:T138	1.47	15	Yes	No	2	2	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	9AUC_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	2.71
Number of Linked Nodes	500
Number of Links	635
Number of Hubs	118
Number of Links mediated by Hubs	413
Number of Communities	17
Number of Nodes involved in Communities	177
Number of Links involved in Communities	262

Path Summary
Number Of Nodes in MetaPath	65
Number Of Links MetaPath	64
Number of Shortest Paths	297578
Length Of Smallest Path	3
Average Path Length	19.8057
Length of Longest Path	41
Minimum Path Strength	1.41
Average Path Strength	5.82268
Maximum Path Strength	19.72
Minimum Path Correlation	0.7
Average Path Correlation	0.963429
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	3.33333
Average % Of Corr. Nodes	55.6178
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	57.1959
Maximum Path Hubs %	100

Details about the values in these tables can be found in the corresponding documentation page .


Code	PLM
PDB Residues	H:H:?1 L:L:?101
Environment Details	Open EMBL-EBI Page
Code	PLM
Name	Palmitic Acid
Synonyms	Palmitinsäure
Identifier
Formula	C16 H32 O2
Molecular Weight	256.424
SMILES
PubChem	985
Formal Charge	0
Total Atoms	50
Total Chiral Atoms	0
Total Bonds	49
Total Aromatic Bonds	0


Code	NAG
PDB Residues	H:H:?2 H:H:?3 H:H:?4
Environment Details	Open EMBL-EBI Page
Code	NAG
Name	N-Acetylglucosamine
Synonyms	N-Acetylglucosamine
Identifier
Formula	C8 H15 N O6
Molecular Weight	221.208
SMILES
PubChem	24139
Formal Charge	0
Total Atoms	30
Total Chiral Atoms	5
Total Bonds	30
Total Aromatic Bonds	0


Code	NFA
PDB Residues	L:L:?37
Environment Details	Open EMBL-EBI Page
Code	NFA
Name	Phenylalanylamide
Synonyms	Phenylalanine amide (S)-2-amino-3-phenylpropanamide Phenylalaninamide L-phenylalanine amide Phenylalanylamide
Identifier
Formula	C9 H12 N2 O
Molecular Weight	164.204
SMILES
PubChem	445694
Formal Charge	0
Total Atoms	24
Total Chiral Atoms	1
Total Bonds	24
Total Aromatic Bonds	6


PDBsum	Open PDBsum Page
Chain	E
Protein	RAMP1
UniProt	O60894
Sequence	>9AUC_nogp_Chain_E C Q E A N Y G A L L R E L C L T Q F Q V D M E A V G E T L W C D W G R T I R S Y R E L A D C T W H M A E K L G C F W P N A E V D R F F L A V H G R Y F R S C P I S G R A V R D P P G S I L Y P F I V V P I T V T L L V T A L V V W Q S K R Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	R
Protein	Receptor
UniProt	P30988
Sequence	>9AUC_nogp_Chain_R V V G R K K M M D A Q Y K C Y D R M Q Q L P A Y Q G E G P Y C N R T W D G W L C W D D T P A G V L S Y Q F C P D Y F P D F D P S E K V T K Y C D E K G V W F K H P E N N R T W S N Y T M C N A F T P E K L K N A Y V L Y Y L A I V G H S L S I F T L V I S L G I F V F F R S L G C Q R V T L H K N M F L T Y I L N S M I I I I H L V E V V P N G E L V R R D P V S C K I L H F F H Q Y M M A C N Y F W M L C E G I Y L H T L I V V A V F T E K Q R L R W Y Y L L G W G F P L V P T T I H A I T R A V Y F N D N C W L S V E T H L L Y I I H G P V M A A L V V N F F F L L N I V R V L V T K M R E T H E A E S H M Y L K A V K A T M I L V P L L G I Q F V V F P W R P S N K M L G K I Y D Y V M H S L I H F Q G F F V A T I Y C F C N N E V Q T T V K R Q W A Q F Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	9AUC	B1	Peptide	Calcitonin	CT (AMY1)	Homo sapiens	Calcitonin gene-related peptide-1	-	Gs/β1/γ2; RAMP1	2.4	2024-04-24	doi.org/10.1021/acs.biochem.4c00114
	9AUC (No Gprot)	B1	Peptide	Calcitonin	CT (AMY1)	Homo sapiens	Calcitonin gene-related peptide-1	-		2.4	2024-04-24	doi.org/10.1021/acs.biochem.4c00114
	7TYF	B1	Peptide	Calcitonin	CT (AMY1)	Homo sapiens	Amylin	-	Gs/β1/γ2; RAMP1	2.2	2022-03-23	doi.org/10.1126/science.abm9609
	7TYF (No Gprot)	B1	Peptide	Calcitonin	CT (AMY1)	Homo sapiens	Amylin	-		2.2	2022-03-23	doi.org/10.1126/science.abm9609
	7TYW	B1	Peptide	Calcitonin	CT (AMY1)	Homo sapiens	Calcitonin-1	-	Gs/β1/γ2; RAMP1	3	2022-03-23	doi.org/10.1126/science.abm9609
	7TYW (No Gprot)	B1	Peptide	Calcitonin	CT (AMY1)	Homo sapiens	Calcitonin-1	-		3	2022-03-23	doi.org/10.1126/science.abm9609
	9BLW	B1	Peptide	Calcitonin	CT (AMY1)	Homo sapiens	Cagrilintide backbone (non-acylated)	-	Gs/β1/γ2; RAMP1	3.2	2025-04-16	To be published
	9BLW (No Gprot)	B1	Peptide	Calcitonin	CT (AMY1)	Homo sapiens	Cagrilintide backbone (non-acylated)	-		3.2	2025-04-16	To be published
	9BP3	B1	Peptide	Calcitonin	CT (AMY1)	Homo sapiens	Cagrilintide	-	Gs/β1/γ2; RAMP1	2.2	2025-04-23	To be published
	9BP3 (No Gprot)	B1	Peptide	Calcitonin	CT (AMY1)	Homo sapiens	Cagrilintide	-		2.2	2025-04-23	To be published

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 9AUC_nogp.zip

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You can also read or download a guide explaining the meaning of all files and numerical data.