Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index Hub Avg Int. Strength Num Of Links Community ConSurf
1E:E:Y32 8.836515
2E:E:R37 12.2971713
3E:E:W59 6.7275407
4E:E:Y66 5.69833619
5E:E:W74 7.61254126
6E:E:M76 10.365414
7E:E:W84 5.56407
8E:E:V89 5.512518
9E:E:F92 10.542515
10E:E:F93 8.11833619
11E:E:H97 7.146519
12E:E:Y100 10.5883618
13E:E:F101 6.29419
14E:E:D113 6.1275439
15E:E:P114 5.38833639
16E:E:S141 4.0575499
17L:L:T6 5.412540
18L:L:F15 8.55400
19L:L:T36 3.15754190
20L:L:P37 7.0025400
21L:L:?38 6.1175420
22R:R:Q52 8.4175416
23R:R:Y53 6.3725411
24R:R:Y56 8.425613
25R:R:M59 4.5415
26R:R:Y65 144143
27R:R:W76 10.2125418
28R:R:D77 7.9425429
29R:R:W79 10.298526
30R:R:L80 10.0725425
31R:R:W82 8.58714729
32R:R:T85 5.68427
33R:R:Y98 7.35833624
34R:R:F99 10.8525425
35R:R:D101 5.82404
36R:R:F102 7.378524
37R:R:D103 6.055453
38R:R:E106 5.184554
39R:R:K110 13.595428
40R:R:C112 4.98429
41R:R:W118 11.526529
42R:R:N124 5.9175485
43R:R:W128 8.53455
44R:R:S129 6.41527
45R:R:N130 11.6275458
46R:R:Y131 8.98167625
47R:R:F137 7.245451
48R:R:Y149 6.97254175
49R:R:I153 4.264177
50R:R:H156 10.43407
51R:R:L163 3.9025408
52R:R:F170 5.262578
53R:R:F173 5.136107
54R:R:L176 4.13254109
55R:R:V181 4.83479
56R:R:M187 6.7575448
57R:R:F188 4.835408
58R:R:T190 6.3625449
59R:R:Y191 7.15714748
60R:R:H201 4.395406
61R:R:P216 5.534204
62R:R:H226 4.1425406
63R:R:Y234 8.276547
64R:R:F235 5.9275465
65R:R:W236 8.34143749
66R:R:M237 5.6449
67R:R:L238 4.992508
68R:R:I242 4.936507
69R:R:Y243 8.07598
70R:R:V249 5.42254216
71R:R:Q257 5.1595
72R:R:L259 6.41405
73R:R:W261 9.74754132
74R:R:Y262 4.728597
75R:R:L265 4.505467
76R:R:W267 8.125449
77R:R:F269 5.62167663
78R:R:P270 4.508569
79R:R:H277 7.9675437
80R:R:R281 8.325637
81R:R:F285 8.00167636
82R:R:D287 6.15433
83R:R:W290 9.01667639
84R:R:T295 9.15434
85R:R:L297 6.1525434
86R:R:Y299 3.5975407
87R:R:H302 6.0025446
88R:R:P304 4.0975469
89R:R:I354 6.415406
90R:R:Q355 6.4925448
91R:R:F356 5.68625847
92R:R:R362 7.974114
93R:R:Y372 7.56254117
94R:R:H377 7.29754157
95R:R:H381 8.6175409
96R:R:Q383 7.3275449
97R:R:F385 7.91405
98R:R:F393 3.9525478
99R:R:T401 3.7025107
100R:R:Q405 3.23404
   

Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index Node1 Node2 Recurrence Int. Strength Hub1? Hub2? Community ConSurf1 ConSurf2
1E:E:F101 E:E:H97 14.56927.92YesYes199
2E:E:H97 R:R:Y56 24.9886.53YesYes193
3E:E:W59 R:R:Y53 10.82096.75YesYes071
4E:E:R37 E:E:V89 13.780115.69YesYes138
5L:L:P37 R:R:R126 97.69682.88YesNo004
6L:L:?38 L:L:P37 85.97784.06YesYes000
7L:L:?38 R:R:D77 38.019710.08YesYes209
8R:R:D77 R:R:W82 39.893710.05YesYes299
9R:R:T75 R:R:W82 73.71893.64NoYes059
10E:E:D90 R:R:T75 74.26312.89NoNo085
11E:E:D90 E:E:V89 29.81322.92NoYes088
12L:L:?38 R:R:S129 46.68857.43YesYes207
13R:R:S129 R:R:W82 39.87873.71YesYes279
14R:R:N124 R:R:R126 97.64144.82YesNo854
15R:R:P86 R:R:T85 13.31933.5NoYes027
16R:R:P86 R:R:Y65 11.37038.34NoYes023
17L:L:S34 R:R:N124 97.85537.45NoYes805
18L:L:S34 R:R:H121 98.23738.37NoNo004
19R:R:H121 R:R:W128 98.448414.81NoYes045
20H:H:?502 R:R:W128 97.95256.13NoYes505
21H:H:?502 R:R:M133 99.91235.07NoNo505
22R:R:E106 R:R:M133 99.47314.06YesNo545
23R:R:D103 R:R:E106 1006.5YesYes534
24R:R:D103 R:R:P104 93.69644.83YesNo033
25R:R:E294 R:R:P104 95.90024.72NoNo033
26L:L:K1 R:R:E294 95.923710.8NoNo003
27L:L:K1 R:R:H296 22.59755.24NoNo002
28E:E:D113 R:R:H296 22.23255.04YesNo092
29L:L:?0 R:R:Y299 79.23893.15NoYes007
30L:L:?0 L:L:K1 80.49875.05NoNo000
31E:E:T130 R:R:P304 11.366.99NoYes699
32R:R:T190 R:R:W236 11.05786.06YesYes499
33R:R:M187 R:R:T190 20.45526.02YesYes489
34R:R:M187 R:R:M237 37.96587.22YesYes489
35R:R:M237 R:R:Y234 62.17833.59YesYes497
36L:L:T6 R:R:Y234 61.46988.74YesYes407
37L:L:T4 L:L:T6 82.52744.71NoYes400
38L:L:T4 R:R:Y299 86.41283.75NoYes007
39R:R:C232 R:R:W267 12.30773.92NoYes089
40R:R:T190 R:R:W267 12.71556.06YesYes499
41R:R:E240 R:R:M187 24.23415.41NoYes098
42R:R:E240 R:R:L183 14.34033.98NoNo098
43R:R:L183 R:R:Y243 13.85337.03NoYes088
44L:L:C2 R:R:H302 12.73714.42NoYes406
45L:L:C2 R:R:L298 12.39694.76NoNo006
46R:R:H277 R:R:R281 12.00712.41YesYes377
47R:R:H277 R:R:L298 11.62465.14YesNo076
48L:L:N3 R:R:W361 10.210515.82NoNo004
49R:R:D103 R:R:K141 11.27185.53YesNo033
50L:L:F15 R:R:K141 10.878619.85YesNo003
51L:L:T6 R:R:F356 30.48793.89YesYes407
52R:R:L298 R:R:V293 11.01512.98NoNo066
53L:L:E14 R:R:V293 10.23725.7NoNo006
54R:R:F99 R:R:W79 13.20919.02YesYes256
55R:R:S91 R:R:W82 10.13313.71NoYes059
56R:R:M237 R:R:Y191 25.55864.79YesYes498
57R:R:L163 R:R:Y191 33.14583.52YesYes088
58R:R:F356 R:R:Q383 28.83824.68YesYes479
59R:R:Q383 R:R:Y191 28.596110.15YesYes498
60R:R:F188 R:R:L163 24.30586.09YesYes088
61R:R:V387 R:R:Y191 24.78963.79NoYes098
62R:R:F188 R:R:V387 24.2193.93YesNo089
63R:R:F170 R:R:F188 39.18385.36YesYes088
64R:R:F170 R:R:V398 31.46052.62YesNo089
65R:R:N395 R:R:V398 30.26228.87NoNo099
66R:R:E397 R:R:N395 29.06293.94NoNo099
67R:R:E397 R:R:L176 12.1143.98NoYes1099
68R:R:E397 R:R:T401 15.74834.23NoYes1097
69R:R:E240 R:R:H184 11.872312.31NoNo099
70R:R:H184 R:R:Y391 10.96454.36NoNo098
71E:E:D90 R:R:Y56 44.44816.9NoYes083
72E:E:F101 E:E:Y100 12.01124.13YesYes198
73L:L:P37 R:R:W79 11.181717.57YesYes006
Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Links and nodes colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
E:E:F83 R:R:N124 4.83 8 No Yes 5 5 2 1
E:E:F83 R:R:R126 20.31 8 No No 5 4 2 1
E:E:D113 R:R:H296 5.04 3 Yes No 9 2 2 1
E:E:I123 R:R:Y299 3.63 0 No Yes 9 7 2 1
L:L:?0 R:R:Y299 3.15 0 No Yes 0 7 0 1
L:L:K1 R:R:E294 10.8 0 No No 0 3 0 1
L:L:K1 R:R:H296 5.24 0 No No 0 2 0 1
L:L:C2 R:R:L298 4.76 4 No No 0 6 0 1
L:L:C2 R:R:H302 4.42 4 No Yes 0 6 0 1
L:L:N3 R:R:W361 15.82 0 No No 0 4 0 1
L:L:T4 R:R:Y299 3.75 4 No Yes 0 7 0 1
L:L:T4 R:R:H302 5.48 4 No Yes 0 6 0 1
L:L:A5 R:R:F356 5.55 0 No Yes 0 7 0 1
L:L:T6 R:R:Y234 8.74 4 Yes Yes 0 7 0 1
L:L:T6 R:R:H302 8.21 4 Yes Yes 0 6 0 1
L:L:T6 R:R:F356 3.89 4 Yes Yes 0 7 0 1
L:L:C7 R:R:H302 5.9 4 No Yes 0 6 0 1
L:L:A8 R:R:H377 2.93 0 No Yes 0 7 0 1
L:L:T9 R:R:H381 6.85 0 No Yes 0 9 0 1
L:L:Q10 R:R:H226 3.71 0 No Yes 0 6 0 1
L:L:L12 R:R:L148 4.15 15 No No 0 5 0 1
L:L:L12 R:R:H377 7.71 15 No Yes 0 7 0 1
L:L:A13 R:R:H201 2.93 0 No Yes 0 6 0 1
L:L:E14 R:R:L291 3.98 16 No No 0 6 0 1
L:L:E14 R:R:V293 5.7 16 No No 0 6 0 1
L:L:F15 R:R:K141 19.85 0 Yes No 0 3 0 1
L:L:F15 R:R:L142 3.65 0 Yes No 0 2 0 1
L:L:L16 R:R:A145 3.15 0 No No 0 4 0 1
L:L:L16 R:R:Y149 3.52 0 No Yes 0 5 0 1
L:L:R17 R:R:V212 5.23 16 No No 0 3 0 1
L:L:R17 R:R:L291 8.5 16 No No 0 6 0 1
L:L:H18 R:R:P104 3.05 0 No No 0 3 0 1
L:L:S20 R:R:Y146 5.09 18 No No 0 2 0 1
L:L:F23 R:R:Y146 7.22 18 No No 0 2 0 1
L:L:F23 R:R:P207 5.78 18 No No 0 3 0 1
L:L:P29 R:R:N135 4.89 0 No No 0 3 0 1
L:L:T30 R:R:F99 14.27 0 No Yes 0 5 0 1
L:L:T30 R:R:D101 8.67 0 No Yes 0 4 0 1
L:L:S34 R:R:H121 8.37 8 No No 0 4 0 1
L:L:S34 R:R:E123 8.62 8 No No 0 4 0 1
L:L:S34 R:R:N124 7.45 8 No Yes 0 5 0 1
L:L:P37 R:R:W79 17.57 0 Yes Yes 0 6 0 1
L:L:P37 R:R:R126 2.88 0 Yes No 0 4 0 1
L:L:?38 R:R:D77 10.08 2 Yes Yes 0 9 0 1
L:L:?38 R:R:S129 7.43 2 Yes Yes 0 7 0 1
L:L:?38 R:R:Y131 2.9 2 Yes Yes 0 5 0 1
L:L:?101 R:R:W361 3.63 0 No No 0 4 0 1
R:R:M48 R:R:W79 4.65 2 No Yes 6 6 2 1
R:R:M48 R:R:Y98 10.78 2 No Yes 6 4 2 2
R:R:D77 R:R:W82 10.05 2 Yes Yes 9 9 1 2
R:R:D77 R:R:S129 5.89 2 Yes Yes 9 7 1 1
R:R:D77 R:R:Y131 5.75 2 Yes Yes 9 5 1 1
R:R:W79 R:R:Y98 4.82 2 Yes Yes 6 4 1 2
R:R:F99 R:R:W79 9.02 2 Yes Yes 5 6 1 1
R:R:W79 R:R:Y131 15.43 2 Yes Yes 6 5 1 1
R:R:L80 R:R:V108 4.47 2 Yes No 5 7 2 2
R:R:L80 R:R:Y131 7.03 2 Yes Yes 5 5 2 1
R:R:V108 R:R:W82 4.9 2 No Yes 7 9 2 2
R:R:K110 R:R:W82 22.05 2 Yes Yes 8 9 2 2
R:R:S129 R:R:W82 3.71 2 Yes Yes 7 9 1 2
R:R:C95 R:R:F102 5.59 2 No Yes 9 4 2 1
R:R:C134 R:R:C95 7.28 2 No No 9 9 2 2
R:R:F99 R:R:Y98 6.19 2 Yes Yes 5 4 1 2
R:R:F102 R:R:F99 13.93 2 Yes Yes 4 5 1 1
R:R:D101 R:R:F102 3.58 0 Yes Yes 4 4 1 1
R:R:D101 R:R:N135 9.42 0 Yes No 4 3 1 1
R:R:C134 R:R:F102 11.17 2 No Yes 9 4 2 1
R:R:D103 R:R:P104 4.83 5 Yes No 3 3 2 1
R:R:D103 R:R:K141 5.53 5 Yes No 3 3 2 1
R:R:E294 R:R:P104 4.72 0 No No 3 3 1 1
R:R:V108 R:R:Y131 13.88 2 No Yes 7 5 2 1
R:R:K110 R:R:S129 6.12 2 Yes Yes 8 7 2 1
R:R:H121 R:R:P122 6.1 0 No No 4 5 1 2
R:R:H121 R:R:W128 14.81 0 No Yes 4 5 1 2
R:R:E123 R:R:N124 6.57 8 No Yes 4 5 1 1
R:R:N124 R:R:R126 4.82 8 Yes No 5 4 1 1
R:R:S129 R:R:Y131 8.9 2 Yes Yes 7 5 1 1
R:R:N135 R:R:T138 2.92 0 No No 3 2 1 2
R:R:L142 R:R:Y146 14.07 0 No No 2 2 1 1
R:R:L148 R:R:Y374 3.52 15 No No 5 6 1 2
R:R:H377 R:R:L148 9 15 Yes No 7 5 1 1
R:R:Y149 R:R:Y150 2.98 17 Yes No 5 4 1 2
R:R:I153 R:R:Y149 9.67 17 Yes Yes 7 5 2 1
R:R:L202 R:R:Y149 11.72 17 No Yes 7 5 2 1
R:R:A152 R:R:H381 7.32 0 No Yes 7 9 2 1
R:R:I153 R:R:L202 4.28 17 Yes No 7 7 2 2
R:R:H156 R:R:I198 17.23 0 Yes No 7 7 2 2
R:R:H156 R:R:H381 10.75 0 Yes Yes 7 9 2 1
R:R:H226 R:R:I197 5.3 0 Yes No 6 5 1 2
R:R:H226 R:R:I198 3.98 0 Yes No 6 7 1 2
R:R:H201 R:R:V205 8.3 0 Yes No 6 7 1 2
R:R:H201 R:R:H226 3.58 0 Yes Yes 6 6 1 1
R:R:P207 R:R:V206 5.3 0 No No 3 3 1 2
R:R:N288 R:R:V212 2.96 0 No No 4 3 2 1
R:R:M230 R:R:Y234 3.59 0 No Yes 6 7 2 1
R:R:M237 R:R:Y234 3.59 4 Yes Yes 9 7 2 1
R:R:V305 R:R:Y234 15.14 0 No Yes 7 7 2 1
R:R:F356 R:R:Y234 10.32 4 Yes Yes 7 7 1 1
R:R:M237 R:R:Q383 6.8 4 Yes Yes 9 9 2 2
R:R:H277 R:R:L298 5.14 3 Yes No 7 6 2 1
R:R:C289 R:R:L291 4.76 0 No No 9 6 2 1
R:R:L298 R:R:V293 2.98 0 No No 6 6 1 1
R:R:W361 R:R:Y299 3.86 0 No Yes 4 7 1 1
R:R:L309 R:R:V305 2.98 0 No No 7 7 2 2
R:R:F356 R:R:L309 3.65 4 Yes No 7 7 1 2
R:R:G353 R:R:Q355 4.93 4 No Yes 9 8 2 2
R:R:F356 R:R:G353 3.01 4 Yes No 7 9 1 2
R:R:F356 R:R:Q355 9.37 4 Yes Yes 7 8 1 2
R:R:Q355 R:R:Q383 7.68 4 Yes Yes 8 9 2 2
R:R:F356 R:R:I380 5.02 4 Yes No 7 6 1 2
R:R:F356 R:R:Q383 4.68 4 Yes Yes 7 9 1 2
R:R:H377 R:R:H381 9.55 15 Yes Yes 7 9 1 1
L:L:F15 R:R:A145 2.77 0 Yes No 0 4 0 1
R:R:H201 R:R:V206 2.77 0 Yes No 6 3 1 2
L:L:V32 R:R:F102 2.62 0 No Yes 0 4 0 1
R:R:G209 R:R:V212 1.84 0 No No 3 3 1 1
L:L:N22 R:R:G209 1.7 0 No No 0 3 0 1
R:R:M306 R:R:P360 1.68 0 No No 4 5 1 2
R:R:D101 R:R:P100 1.61 0 Yes No 4 4 1 2
L:L:T6 R:R:M306 1.51 4 Yes No 0 4 0 1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB 9BP3_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.
Net Summary
Imin 2.88
Number of Linked Nodes 498
Number of Links 607
Number of Hubs 100
Number of Links mediated by Hubs 349
Number of Communities 21
Number of Nodes involved in Communities 156
Number of Links involved in Communities 217
Path Summary
Number Of Nodes in MetaPath 74
Number Of Links MetaPath 73
Number of Shortest Paths 368201
Length Of Smallest Path 3
Average Path Length 24.6268
Length of Longest Path 50
Minimum Path Strength 1.19
Average Path Strength 6.28838
Maximum Path Strength 22.81
Minimum Path Correlation 0.7
Average Path Correlation 0.966539
Maximum Path Correlation 1
Minimum % Of Corr. Nodes 2.5641
Average % Of Corr. Nodes 49.0831
Maximum % Of Corr. Nodes 100
Minimum Path Hubs % 0
Average Path Hubs % 49.7329
Maximum Path Hubs % 100
AnnotationTypeLinks
Gene OntologyMolecular Function
Gene OntologyBiological Process
Gene OntologyCellular Component
SCOP2Domain Identifier• Transducin (heterotrimeric G protein), gamma chain   • G protein-coupled receptor-like   • RAMP1-like
SCOP2Family Identifier• Transducin (heterotrimeric G protein), gamma chain   • G protein-coupled receptor-like   • RAMP1-like
Membrane Protein Annotations-• Orientations of Proteins in Membranes database (OPM)   • Protein Data Bank of Transmembrane Proteins (PDBTM)   • MemProtMD


Details about the values in these tables can be found in the corresponding documentation page .
CodeNAG
PDB ResiduesH:H:?501 H:H:?502 H:H:?503
Environment DetailsOpen EMBL-EBI Page
CodeNAG
NameN-Acetylglucosamine
SynonymsN-Acetylglucosamine
Identifier
FormulaC8 H15 N O6
Molecular Weight221.208
SMILES
PubChem24139
Formal Charge0
Total Atoms30
Total Chiral Atoms5
Total Bonds30
Total Aromatic Bonds0

CodeGGL
PDB ResiduesL:L:?0
Environment DetailsOpen EMBL-EBI Page
CodeGGL
NameGlutamic acid
SynonymsGlutamic acid
Identifier
FormulaC5 H9 N O4
Molecular Weight147.129
SMILES
PubChem44272391
Formal Charge0
Total Atoms19
Total Chiral Atoms1
Total Bonds18
Total Aromatic Bonds0

CodeNH2
PDB ResiduesL:L:?38
Environment DetailsOpen EMBL-EBI Page
CodeNH2
NameAMINO GROUP
Synonyms
Identifier
FormulaH2 N
Molecular Weight16.023
SMILES
PubChem123329
Formal Charge0
Total Atoms3
Total Chiral Atoms0
Total Bonds2
Total Aromatic Bonds0

CodeA1B
PDB ResiduesL:L:?101
Environment DetailsOpen EMBL-EBI Page
CodeA1B
Name1-deoxy-alpha-L-xylulofuranose-1,2-borate
Synonyms
Identifier
FormulaC5 H10 B O6
Molecular Weight176.94
SMILES
PubChem118797262
Formal Charge-1
Total Atoms22
Total Chiral Atoms3
Total Bonds23
Total Aromatic Bonds0

PDBsumOpen PDBsum Page
ChainE
ProteinRAMP1
UniProtO60894
Sequence
>9BP3_nogp_Chain_E
YGALLRELC LTQFQVDME AVGETLWCD WGRTIRSYR ELADCTWHM 
AEKLGCFWP NAEVDRFFL AVHGRYFRS CPISGRAVR DPPGSILYP 
FIVVPITVT LLVTALVVW QSKRTE


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

ChainR
ProteinReceptor
UniProtP30988
Sequence
>9BP3_nogp_Chain_R
YVVGRKKMM DAQYKCYDR MQQLPAYQG EGPYCNRTW DGWLCWDDT 
PAGVLSYQF CPDYFPDFD PSEKVTKYC DEKGVWFKH PENNRTWSN 
YTMCNAFTP EKLKNAYVL YYLAIVGHS LSIFTLVIS LGIFVFFRS 
LGCQRVTLH KNMFLTYIL NSMIIIIHL VEVVPNGEL VRRDPVSCK 
ILHFFHQYM MACNYFWML CEGIYLHTL IVVAVFTEK QRLRWYYLL 
GWGFPLVPT TIHAITRAV YFNDNCWLS VETHLLYII HGPVMAALV 
VNFFFLLNI VRVLVTKMR ETHEAESHM YLKAVKATM ILVPLLGIQ 
FVVFPWRPS NKMLGKIYD YVMHSLIHF QGFFVATIY CFCNNEVQT 
TVKRQWAQF


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  




This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
9AUCB1PeptideCalcitoninCT (AMY1)Homo sapiensCalcitonin gene-related peptide-1-Gs/β1/γ2; RAMP12.42024-04-24doi.org/10.1021/acs.biochem.4c00114
9AUC (No Gprot) B1PeptideCalcitoninCT (AMY1)Homo sapiensCalcitonin gene-related peptide-1-2.42024-04-24doi.org/10.1021/acs.biochem.4c00114
7TYFB1PeptideCalcitoninCT (AMY1)Homo sapiensAmylin-Gs/β1/γ2; RAMP12.22022-03-23doi.org/10.1126/science.abm9609
7TYF (No Gprot) B1PeptideCalcitoninCT (AMY1)Homo sapiensAmylin-2.22022-03-23doi.org/10.1126/science.abm9609
7TYWB1PeptideCalcitoninCT (AMY1)Homo sapiensCalcitonin-1-Gs/β1/γ2; RAMP132022-03-23doi.org/10.1126/science.abm9609
7TYW (No Gprot) B1PeptideCalcitoninCT (AMY1)Homo sapiensCalcitonin-1-32022-03-23doi.org/10.1126/science.abm9609
9BLWB1PeptideCalcitoninCT (AMY1)Homo sapiensCagrilintide backbone (non-acylated)-Gs/β1/γ2; RAMP13.22025-04-16To be published
9BLW (No Gprot) B1PeptideCalcitoninCT (AMY1)Homo sapiensCagrilintide backbone (non-acylated)-3.22025-04-16To be published
9BP3B1PeptideCalcitoninCT (AMY1)Homo sapiensCagrilintide-Gs/β1/γ2; RAMP12.22025-04-23To be published
9BP3 (No Gprot) B1PeptideCalcitoninCT (AMY1)Homo sapiensCagrilintide-2.22025-04-23To be published




You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 9BP3_nogp.zip



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