psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?2	L:L:D1	7.79	Yes	No	1	0	0
2	L:L:D1	L:L:M3	4.16	No	Yes	1	0	0
3	L:L:?2	L:L:M3	8.11	Yes	Yes	1	0	0
4	L:L:?2	R:R:P101	5.89	Yes	No	1	0	5
5	L:L:?2	R:R:F107	5.24	Yes	Yes	1	0	8
6	L:L:?2	R:R:F185	5.24	Yes	No	1	0	4
7	L:L:?2	R:R:M195	16.22	Yes	No	1	0	4
8	L:L:?2	R:R:R197	13.94	Yes	No	1	0	4
9	L:L:M3	R:R:E344	5.41	Yes	Yes	1	0	1
10	L:L:M3	R:R:S348	4.6	Yes	No	0	0	5
11	L:L:G4	R:R:R197	4.5	No	No	1	0	4
12	L:L:G4	R:R:R336	4.5	No	Yes	1	0	4
13	L:L:G4	R:R:E344	8.19	No	Yes	1	0	1
14	L:L:W5	R:R:N333	5.65	Yes	No	0	0	7
15	L:L:W5	R:R:R336	15.99	Yes	Yes	0	0	4
16	L:L:W5	R:R:A343	3.89	Yes	No	0	0	4
17	L:L:W5	R:R:L347	4.56	Yes	No	0	0	5
18	L:L:W5	R:R:I352	17.62	Yes	No	0	0	5
19	L:L:M6	R:R:N98	7.01	No	Yes	1	0	7
20	L:L:M6	R:R:M121	4.33	No	Yes	1	0	7
21	L:L:M6	R:R:C196	4.86	No	No	1	0	9
22	L:L:D7	R:R:Y176	9.2	No	Yes	0	0	7
23	L:L:D7	R:R:H210	5.04	No	No	0	0	6
24	L:L:D7	R:R:N333	4.04	No	No	0	0	7
25	L:L:F8	R:R:V125	7.87	No	No	0	0	7
26	L:L:F8	R:R:F330	5.36	No	Yes	0	0	7
27	L:L:?9	R:R:N98	10.2	No	Yes	0	0	7
28	L:L:?9	R:R:L356	6.85	No	No	0	0	6
29	R:R:V43	R:R:W39	4.9	No	Yes	0	5	1
30	R:R:N102	R:R:Q44	6.6	No	Yes	5	6	4
31	R:R:Q44	R:R:S353	10.11	Yes	No	5	4	5
32	R:R:F354	R:R:Q44	4.68	No	Yes	5	4	4
33	R:R:I45	R:R:L103	4.28	No	No	0	5	5
34	R:R:L357	R:R:L47	4.15	No	No	0	7	5
35	R:R:L99	R:R:Y48	15.24	No	No	0	6	7
36	R:R:L357	R:R:Y48	12.89	No	No	0	7	7
37	R:R:Y360	R:R:Y48	4.96	Yes	No	0	7	7
38	R:R:L50	R:R:L54	6.92	No	No	0	4	5
39	R:R:I51	R:R:L357	4.28	No	No	0	7	7
40	R:R:F52	R:R:V56	5.24	Yes	No	0	5	6
41	R:R:C91	R:R:F52	4.19	No	Yes	8	7	5
42	R:R:F52	R:R:M95	4.98	Yes	No	8	5	7
43	R:R:F52	R:R:P96	4.33	Yes	No	0	5	8
44	R:R:N59	R:R:S55	4.47	Yes	No	0	9	8
45	R:R:C91	R:R:S55	6.89	No	No	0	7	8
46	R:R:L88	R:R:V56	4.47	No	No	0	7	6
47	R:R:L57	R:R:L61	4.15	No	No	0	4	7
48	R:R:G58	R:R:P367	4.06	No	No	0	8	9
49	R:R:A84	R:R:N59	4.69	No	Yes	0	9	9
50	R:R:D87	R:R:N59	6.73	Yes	Yes	0	9	9
51	R:R:N59	R:R:P367	11.4	Yes	No	0	9	9
52	R:R:C371	R:R:V62	6.83	No	No	0	8	9
53	R:R:I63	R:R:L81	4.28	No	No	0	7	6
54	R:R:F385	R:R:T64	5.19	Yes	No	0	6	4
55	R:R:F377	R:R:V65	3.93	Yes	Yes	0	9	8
56	R:R:F381	R:R:V65	5.24	No	Yes	7	7	8
57	R:R:T384	R:R:V65	12.69	No	Yes	7	6	8
58	R:R:F385	R:R:V65	3.93	Yes	Yes	7	6	8
59	R:R:L66	R:R:M72	4.24	No	No	0	7	8
60	R:R:L66	R:R:N77	5.49	No	No	0	7	9
61	R:R:I67	R:R:L81	4.28	No	No	0	3	6
62	R:R:R68	R:R:T384	11.64	No	No	0	5	6
63	R:R:N69	R:R:R71	6.03	No	No	0	6	6
64	R:R:M72	R:R:N69	14.02	No	No	0	8	6
65	R:R:K70	R:R:R73	13.61	No	No	0	7	8
66	R:R:N77	R:R:T74	5.85	No	No	0	9	7
67	R:R:A158	R:R:I78	4.87	No	Yes	0	7	5
68	R:R:A134	R:R:F79	4.16	No	Yes	0	8	8
69	R:R:F79	R:R:I135	3.77	Yes	No	0	8	9
70	R:R:E138	R:R:F79	5.83	Yes	Yes	0	9	8
71	R:R:F79	R:R:V161	5.24	Yes	No	0	8	6
72	R:R:F79	R:R:I162	3.77	Yes	No	0	8	7
73	R:R:L80	R:R:Y370	4.69	No	Yes	0	8	9
74	R:R:N131	R:R:S82	5.96	No	No	0	8	9
75	R:R:I162	R:R:S82	7.74	No	No	0	7	9
76	R:R:S82	R:R:W166	6.18	No	No	0	9	9
77	R:R:D87	R:R:L83	5.43	Yes	No	6	9	9
78	R:R:L132	R:R:L83	4.15	No	No	6	8	9
79	R:R:L83	R:R:N366	6.87	No	No	6	9	9
80	R:R:S86	R:R:V127	4.85	No	Yes	0	8	8
81	R:R:S128	R:R:S86	4.89	No	No	0	9	8
82	R:R:D87	R:R:S128	4.42	Yes	No	0	9	9
83	R:R:D87	R:R:S363	11.78	Yes	No	0	9	9
84	R:R:D87	R:R:N366	9.42	Yes	No	6	9	9
85	R:R:L88	R:R:L92	4.15	No	No	0	7	5
86	R:R:F93	R:R:M89	7.46	No	No	0	5	7
87	R:R:C94	R:R:L90	4.76	No	Yes	0	7	8
88	R:R:L90	R:R:S124	9.01	Yes	No	0	8	6
89	R:R:L90	R:R:V125	5.96	Yes	No	0	8	7
90	R:R:L90	R:R:S363	6.01	Yes	No	0	8	9
91	R:R:C91	R:R:M95	6.48	No	No	8	7	7
92	R:R:F120	R:R:F93	17.15	No	No	0	5	5
93	R:R:C94	R:R:M121	8.1	No	Yes	0	7	7
94	R:R:C94	R:R:Y360	8.06	No	Yes	0	7	7
95	R:R:M95	R:R:Y360	8.38	No	Yes	0	7	7
96	R:R:F109	R:R:F97	8.57	Yes	No	0	6	6
97	R:R:F97	R:R:T117	9.08	No	No	0	6	6
98	R:R:M121	R:R:N98	4.21	Yes	Yes	1	7	7
99	R:R:N98	R:R:Y360	9.3	Yes	Yes	0	7	7
100	R:R:L103	R:R:L99	8.3	No	No	0	5	6
101	R:R:F109	R:R:I100	5.02	Yes	No	0	6	5
102	R:R:F107	R:R:P101	5.78	Yes	No	1	8	5
103	R:R:N102	R:R:S353	5.96	No	No	5	6	5
104	R:R:I108	R:R:L104	4.28	No	No	0	4	4
105	R:R:D106	R:R:K187	9.68	No	No	0	4	2
106	R:R:F107	R:R:F109	8.57	Yes	Yes	0	8	6
107	R:R:C114	R:R:F107	5.59	No	Yes	1	9	8
108	R:R:F107	R:R:L182	4.87	Yes	Yes	0	8	5
109	R:R:C196	R:R:F107	11.17	No	Yes	1	9	8
110	R:R:F109	R:R:I108	7.54	Yes	No	0	6	4
111	R:R:F109	R:R:V113	7.87	Yes	No	0	6	5
112	R:R:K115	R:R:S111	4.59	No	No	0	5	4
113	R:R:N181	R:R:S111	5.96	No	No	0	5	4
114	R:R:C114	R:R:C196	7.28	No	No	1	9	9
115	R:R:F120	R:R:T116	3.89	No	No	0	5	4
116	R:R:M121	R:R:T118	4.52	Yes	No	0	7	6
117	R:R:T118	R:R:Y176	6.24	No	Yes	0	6	7
118	R:R:S180	R:R:T118	9.59	No	No	0	6	6
119	R:R:F120	R:R:Y119	6.19	No	Yes	0	5	6
120	R:R:T123	R:R:Y119	7.49	No	Yes	9	6	6
121	R:R:F170	R:R:Y119	5.16	No	Yes	9	4	6
122	R:R:P177	R:R:Y119	12.52	No	Yes	0	6	6
123	R:R:S169	R:R:T123	6.4	No	No	0	8	6
124	R:R:F170	R:R:T123	6.49	No	No	9	4	6
125	R:R:V125	R:R:W326	6.13	No	Yes	0	7	8
126	R:R:S126	R:R:S169	6.52	No	No	0	7	8
127	R:R:L217	R:R:S126	9.01	No	No	0	7	7
128	R:R:N131	R:R:V127	5.91	No	Yes	0	8	8
129	R:R:T165	R:R:V127	4.76	No	Yes	0	7	8
130	R:R:V127	R:R:W166	14.71	Yes	No	0	8	9
131	R:R:S169	R:R:V127	4.85	No	Yes	0	8	8
132	R:R:F322	R:R:T129	5.19	Yes	No	0	9	8
133	R:R:L132	R:R:N366	5.49	No	No	6	8	9
134	R:R:I135	R:R:R139	6.26	No	No	4	9	9
135	R:R:I135	R:R:Y370	6.04	No	Yes	4	9	9
136	R:R:A136	R:R:Y229	6.67	No	Yes	0	9	9
137	R:R:L137	R:R:V224	4.47	No	No	0	6	7
138	R:R:E138	R:R:W152	6.54	Yes	Yes	3	9	5
139	R:R:E138	R:R:Q153	8.92	Yes	Yes	3	9	7
140	R:R:E138	R:R:H157	8.62	Yes	Yes	3	9	7
141	R:R:R139	R:R:Y229	6.17	No	Yes	4	9	9
142	R:R:R139	R:R:Y370	8.23	No	Yes	4	9	9
143	R:R:C144	R:R:Y140	8.06	No	No	0	7	8
144	R:R:L231	R:R:Y140	8.21	No	No	0	5	8
145	R:R:S141	R:R:S149	4.89	No	Yes	3	6	8
146	R:R:S141	R:R:W152	4.94	No	Yes	3	6	5
147	R:R:Q153	R:R:S141	4.33	Yes	No	3	7	6
148	R:R:K145	R:R:Q148	4.07	No	No	0	6	5
149	R:R:S149	R:R:W152	7.41	Yes	Yes	3	8	5
150	R:R:Q153	R:R:S149	8.66	Yes	Yes	3	7	8
151	R:R:Q153	R:R:W152	15.33	Yes	Yes	3	7	5
152	R:R:H157	R:R:W152	8.46	Yes	Yes	3	7	5
153	R:R:S156	R:R:T154	4.8	No	No	0	5	8
154	R:R:H157	R:R:V161	4.15	Yes	No	0	7	6
155	R:R:F170	R:R:W166	4.01	No	No	0	4	9
156	R:R:I172	R:R:M173	4.37	No	No	0	6	8
157	R:R:M173	R:R:Y176	4.79	No	Yes	0	8	7
158	R:R:P175	R:R:Y179	4.17	No	No	0	8	5
159	R:R:F198	R:R:Y176	20.63	No	Yes	0	5	7
160	R:R:W209	R:R:Y176	10.61	No	Yes	0	8	7
161	R:R:I178	R:R:Y179	15.71	No	No	0	5	5
162	R:R:F198	R:R:Y179	6.19	No	No	0	5	5
163	R:R:L182	R:R:N194	5.49	Yes	No	0	5	3
164	R:R:A193	R:R:F185	8.32	No	No	0	3	4
165	R:R:F185	R:R:M195	12.44	No	No	1	4	4
166	R:R:M195	R:R:R197	4.96	No	No	1	4	4
167	R:R:F198	R:R:L200	6.09	No	Yes	0	5	4
168	R:R:L200	R:R:M205	4.24	Yes	No	0	4	4
169	R:R:L200	R:R:Q206	5.32	Yes	No	0	4	5
170	R:R:L200	R:R:W209	5.69	Yes	No	0	4	8
171	R:R:M205	R:R:P201	6.71	No	No	0	4	5
172	R:R:M205	R:R:N202	11.22	No	No	0	4	5
173	R:R:D203	R:R:Q207	9.14	No	No	0	2	4
174	R:R:H210	R:R:Q206	9.89	No	No	0	6	5
175	R:R:Q207	R:R:Y338	24.8	No	No	0	4	5
176	R:R:F212	R:R:W209	8.02	No	No	0	5	8
177	R:R:A337	R:R:H210	8.78	No	No	0	6	6
178	R:R:F212	R:R:L213	4.87	No	No	0	5	7
179	R:R:L213	R:R:L217	6.92	No	No	0	7	7
180	R:R:L214	R:R:L215	4.15	Yes	No	0	7	3
181	R:R:F218	R:R:L214	4.87	Yes	Yes	2	8	7
182	R:R:F330	R:R:L214	8.53	Yes	Yes	2	7	7
183	R:R:F330	R:R:L217	4.87	Yes	No	0	7	7
184	R:R:F218	R:R:W326	4.01	Yes	Yes	2	8	8
185	R:R:F218	R:R:M327	8.71	Yes	No	0	8	6
186	R:R:F218	R:R:F330	11.79	Yes	Yes	2	8	7
187	R:R:F219	R:R:I220	8.79	No	No	0	6	6
188	R:R:F219	R:R:V223	5.24	No	No	0	6	4
189	R:R:M225	R:R:Y229	4.79	No	Yes	0	8	9
190	R:R:L315	R:R:Y229	9.38	No	Yes	0	8	9
191	R:R:I318	R:R:Y229	6.04	No	Yes	4	9	9
192	R:R:V319	R:R:Y229	3.79	No	Yes	0	8	9
193	R:R:Y229	R:R:Y370	4.96	Yes	Yes	4	9	9
194	R:R:I312	R:R:S233	6.19	No	No	0	8	6
195	R:R:L315	R:R:S233	4.5	No	No	0	8	6
196	R:R:E235	R:R:L234	3.98	No	No	0	6	4
197	R:R:K308	R:R:L236	7.05	No	No	0	8	9
198	R:R:L305	R:R:Y237	4.69	No	No	0	4	6
199	R:R:K309	R:R:L305	5.64	No	No	0	6	4
200	R:R:R310	R:R:R313	7.46	No	No	0	8	7
201	R:R:M314	R:R:M373	4.33	No	No	0	9	7
202	R:R:I318	R:R:I369	5.89	No	No	0	9	9
203	R:R:I318	R:R:Y370	6.04	No	Yes	4	9	9
204	R:R:F322	R:R:W326	7.02	Yes	Yes	2	9	8
205	R:R:C325	R:R:W326	3.92	No	Yes	0	8	8
206	R:R:F330	R:R:W326	6.01	Yes	Yes	2	7	8
207	R:R:S359	R:R:W326	8.65	No	Yes	0	7	8
208	R:R:S362	R:R:W326	8.65	No	Yes	0	9	8
209	R:R:I329	R:R:N333	7.08	No	No	0	7	7
210	R:R:I329	R:R:L356	4.28	No	No	0	7	6
211	R:R:I329	R:R:S359	4.64	No	No	0	7	7
212	R:R:A343	R:R:W335	7.78	No	Yes	0	4	5
213	R:R:R346	R:R:W335	4	No	Yes	0	4	5
214	R:R:L347	R:R:W335	4.56	No	Yes	0	5	5
215	R:R:R336	R:R:T340	3.88	Yes	No	1	4	2
216	R:R:E344	R:R:R336	4.65	Yes	Yes	1	1	4
217	R:R:D339	R:R:S342	11.78	No	No	0	4	4
218	R:R:E344	R:R:T340	7.06	Yes	No	1	1	2
219	R:R:P351	R:R:T350	5.25	No	No	0	4	3
220	R:R:I352	R:R:I355	4.42	No	No	0	5	6
221	R:R:F354	R:R:S353	7.93	No	No	5	4	5
222	R:R:L356	R:R:Y360	8.21	No	Yes	0	6	7
223	R:R:S359	R:R:Y360	3.82	No	Yes	0	7	7
224	R:R:C371	R:R:F377	8.38	No	Yes	0	8	9
225	R:R:F372	R:R:F377	10.72	No	Yes	0	6	9
226	R:R:K375	R:R:R378	12.38	No	No	0	6	9
227	R:R:K375	R:R:L379	21.15	No	No	0	6	5
228	R:R:F381	R:R:F385	8.57	No	Yes	7	7	6
229	R:R:F385	R:R:T384	11.67	Yes	No	7	6	6
230	R:R:F377	R:R:M72	3.73	Yes	No	0	9	8
231	R:R:F381	R:R:M382	3.73	No	No	0	7	5
232	R:R:F212	R:R:L216	3.65	No	No	0	5	5
233	R:R:I232	R:R:Y140	3.63	No	No	0	9	8
234	R:R:I312	R:R:Y237	3.63	No	No	0	8	6
235	R:R:P184	R:R:V183	3.53	No	No	0	1	3
236	R:R:P221	R:R:T129	3.5	No	No	0	9	8
237	R:R:G122	R:R:M173	3.49	No	No	0	6	8
238	R:R:A84	R:R:V62	3.39	No	No	0	9	9
239	R:R:A158	R:R:V75	3.39	No	No	0	7	7
240	R:R:I220	R:R:P221	3.39	No	No	0	6	9
241	R:R:I355	R:R:P328	3.39	No	No	0	6	9
242	R:R:L358	R:R:P328	3.28	No	No	0	8	9
243	R:R:C364	R:R:I51	3.27	No	No	0	7	7
244	R:R:N194	R:R:P184	3.26	No	No	0	3	1
245	R:R:A84	R:R:I63	3.25	No	No	0	9	7
246	R:R:F322	R:R:F323	3.22	Yes	No	2	9	6
247	R:R:V133	R:R:V224	3.21	No	No	0	7	7
248	R:R:A193	R:R:K187	3.21	No	No	0	3	2
249	R:R:C364	R:R:L54	3.17	No	No	0	7	5
250	R:R:T60	R:R:V56	3.17	No	No	0	4	6
251	R:R:T74	R:R:T76	3.14	No	No	0	7	8
252	R:R:I63	R:R:V85	3.07	No	No	0	7	6
253	R:R:I369	R:R:V317	3.07	No	No	0	9	7
254	R:R:C144	R:R:E235	3.04	No	No	0	7	6
255	R:R:A142	R:R:Q153	3.03	No	Yes	0	8	7
256	R:R:F322	R:R:G222	3.01	Yes	No	2	9	6
257	R:R:F323	R:R:G222	3.01	No	No	2	6	6
258	R:R:L182	R:R:S111	3	Yes	No	0	5	4
259	R:R:L47	R:R:V43	2.98	No	No	0	5	5
260	R:R:L231	R:R:V227	2.98	No	No	0	5	5
261	R:R:L236	R:R:V311	2.98	No	No	0	9	9
262	R:R:L321	R:R:V317	2.98	No	No	0	6	7
263	R:R:L324	R:R:V320	2.98	No	No	0	5	6
264	R:R:L321	R:R:V365	2.98	No	No	0	6	7
265	R:R:L130	R:R:T165	2.95	No	No	0	6	7
266	R:R:I162	R:R:I78	2.94	No	Yes	0	7	5
267	R:R:I143	R:R:I232	2.94	No	No	0	9	9
268	R:R:I369	R:R:M314	2.92	No	No	0	9	9
269	R:R:I78	R:R:K155	2.91	Yes	No	0	5	4
270	R:R:I232	R:R:L315	2.85	No	No	0	9	8
271	R:R:K308	R:R:L305	2.82	No	No	0	8	4
272	R:R:L99	R:R:Q44	2.66	No	Yes	0	6	4
273	R:R:L147	R:R:Q148	2.66	No	No	0	7	5
274	R:R:N189	R:R:Q191	2.64	No	No	0	4	2
275	R:R:A42	R:R:W39	2.59	No	Yes	0	6	1
276	R:R:T174	R:R:Y119	2.5	No	Yes	0	4	6
277	R:R:T211	R:R:Y338	2.5	No	No	0	6	5
278	R:R:S342	R:R:W335	2.47	No	Yes	0	4	5
279	R:R:F372	R:R:L61	2.44	No	No	0	6	7
280	R:R:F385	R:R:L61	2.44	Yes	No	0	6	7
281	R:R:Q40	R:R:W39	2.19	No	Yes	0	1	1
282	R:R:G349	R:R:P351	2.03	No	No	0	3	4
283	R:R:A383	R:R:G380	1.95	No	No	0	5	8
284	R:R:G349	R:R:S348	1.86	No	No	0	3	5
285	R:R:G380	R:R:V65	1.84	No	Yes	0	8	8
286	R:R:A136	R:R:A228	1.79	No	No	0	9	6
287	R:R:P221	R:R:V133	1.77	No	No	0	9	7
288	R:R:G110	R:R:L182	1.71	No	Yes	0	7	5
289	R:R:C364	R:R:T361	1.69	No	No	0	7	5
290	R:R:K145	R:R:P146	1.67	No	No	0	6	8
291	R:R:A332	R:R:I352	1.62	No	No	0	5	5
292	R:R:P41	R:R:Q40	1.58	No	No	0	4	1
293	R:R:A334	R:R:L214	1.58	No	Yes	0	6	7
294	R:R:I316	R:R:V320	1.54	No	No	0	7	6
295	R:R:A341	R:R:D339	1.54	No	No	0	1	4
296	R:R:K145	R:R:S149	1.53	No	Yes	0	6	8
297	R:R:A337	R:R:Q207	1.52	No	No	0	6	4
298	R:R:L321	R:R:V320	1.49	No	No	0	6	6
299	R:R:N202	R:R:V204	1.48	No	No	0	5	2
300	R:R:K105	R:R:K187	1.44	No	No	0	4	2
301	R:R:F385	R:R:P386	1.44	Yes	No	0	6	1
302	R:R:I78	R:R:L159	1.43	Yes	No	0	5	5
303	R:R:I172	R:R:L168	1.43	No	No	0	6	5
304	R:R:H157	R:R:T154	1.37	Yes	No	0	7	8
305	R:R:L199	R:R:Q206	1.33	No	No	0	4	5
306	R:R:L234	R:R:Q238	1.33	No	No	0	4	5
307	R:R:F372	R:R:I368	1.26	No	No	0	6	6
308	R:R:K155	R:R:R73	1.24	No	No	0	4	8
309	R:R:K309	R:R:R313	1.24	No	No	0	6	7
310	R:R:M314	R:R:R313	1.24	No	No	0	9	7
311	R:R:V151	R:R:W152	1.23	No	Yes	0	5	5
312	R:R:F52	R:R:L53	1.22	Yes	No	0	5	4
313	R:R:L147	R:R:R150	1.21	No	No	0	7	6
314	R:R:E38	R:R:W39	1.09	No	Yes	0	3	1
315	R:R:F377	R:R:R378	1.07	Yes	No	0	9	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:?2	8.91857	7	1	0
2	L:L:M3	5.57	4	1	0
3	L:L:W5	9.542	5	0	0
4	R:R:W39	2.6925	4	0	1
5	R:R:Q44	6.0125	4	5	4
6	R:R:F52	3.992	5	8	5
7	R:R:N59	6.8225	4	0	9
8	R:R:V65	5.526	5	7	8
9	R:R:I78	3.0375	4	0	5
10	R:R:F79	4.554	5	0	8
11	R:R:D87	7.556	5	6	9
12	R:R:L90	6.435	4	0	8
13	R:R:N98	7.68	4	1	7
14	R:R:F107	6.87	6	1	8
15	R:R:F109	7.514	5	0	6
16	R:R:Y119	6.772	5	9	6
17	R:R:M121	5.29	4	1	7
18	R:R:V127	7.016	5	0	8
19	R:R:E138	7.4775	4	3	9
20	R:R:S149	5.6225	4	3	8
21	R:R:W152	7.31833	6	3	5
22	R:R:Q153	8.054	5	3	7
23	R:R:H157	5.65	4	3	7
24	R:R:Y176	10.294	5	0	7
25	R:R:L182	3.7675	4	0	5
26	R:R:L200	5.335	4	0	4
27	R:R:L214	4.7825	4	2	7
28	R:R:F218	7.345	4	2	8
29	R:R:Y229	5.97143	7	4	9
30	R:R:F322	4.61	4	2	9
31	R:R:W326	6.34143	7	2	8
32	R:R:F330	7.312	5	2	7
33	R:R:W335	4.7025	4	0	5
34	R:R:R336	7.255	4	1	4
35	R:R:E344	6.3275	4	1	1
36	R:R:Y360	7.12167	6	0	7
37	R:R:Y370	5.992	5	4	9
38	R:R:F377	5.566	5	0	9
39	R:R:F385	5.54	6	7	6

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:W5	R:R:R336	10.0057	15.99	Yes	Yes	0	0	4
2	L:L:W5	R:R:N333	23.9444	5.65	Yes	No	0	0	7
3	L:L:?2	R:R:F107	11.7505	5.24	Yes	Yes	1	0	8
4	R:R:C196	R:R:F107	23.4853	11.17	No	Yes	1	9	8
5	L:L:M6	R:R:C196	24.892	4.86	No	No	1	0	9
6	L:L:M6	R:R:M121	18.8586	4.33	No	Yes	1	0	7
7	R:R:C94	R:R:M121	24.3782	8.1	No	Yes	0	7	7
8	R:R:C94	R:R:L90	35.3959	4.76	No	Yes	0	7	8
9	R:R:N98	R:R:Y360	10.459	9.3	Yes	Yes	0	7	7
10	R:R:S359	R:R:Y360	20.8359	3.82	No	Yes	0	7	7
11	R:R:S359	R:R:W326	32.8169	8.65	No	Yes	0	7	8
12	R:R:F330	R:R:W326	35.1888	6.01	Yes	Yes	2	7	8
13	R:R:Y360	R:R:Y48	27.6118	4.96	Yes	No	0	7	7
14	R:R:L357	R:R:Y48	17.2955	12.89	No	No	0	7	7
15	R:R:M95	R:R:Y360	12.9697	8.38	No	Yes	0	7	7
16	R:R:C91	R:R:S55	13.7805	6.89	No	No	0	7	8
17	R:R:N59	R:R:S55	13.8977	4.47	Yes	No	0	9	8
18	R:R:L90	R:R:S363	39.0282	6.01	Yes	No	0	8	9
19	R:R:D87	R:R:S363	39.1298	11.78	Yes	No	0	9	9
20	R:R:D87	R:R:N59	28.5047	6.73	Yes	Yes	0	9	9
21	R:R:A84	R:R:N59	30.6344	4.69	No	Yes	0	9	9
22	R:R:A84	R:R:V62	26.1015	3.39	No	No	0	9	9
23	R:R:C371	R:R:V62	25.1793	6.83	No	No	0	8	9
24	R:R:C371	R:R:F377	24.3196	8.38	No	Yes	0	8	9
25	R:R:D87	R:R:S128	51.8825	4.42	Yes	No	0	9	9
26	R:R:S128	R:R:S86	51.8571	4.89	No	No	0	9	8
27	R:R:S86	R:R:V127	52.0193	4.85	No	Yes	0	8	8
28	R:R:N131	R:R:V127	49.8564	5.91	No	Yes	0	8	8
29	R:R:N131	R:R:S82	49.5535	5.96	No	No	0	8	9
30	R:R:I162	R:R:S82	100	7.74	No	No	0	7	9
31	R:R:V127	R:R:W166	50.7493	14.71	Yes	No	0	8	9
32	R:R:S82	R:R:W166	51.2768	6.18	No	No	0	9	9
33	R:R:F79	R:R:I162	93.482	3.77	Yes	No	0	8	7
34	R:R:F79	R:R:I135	68.7794	3.77	Yes	No	0	8	9
35	R:R:I135	R:R:Y370	43.4185	6.04	No	Yes	4	9	9
36	R:R:F330	R:R:L217	37.8988	4.87	Yes	No	0	7	7
37	R:R:L217	R:R:S126	53.6586	9.01	No	No	0	7	7
38	R:R:S126	R:R:S169	53.8305	6.52	No	No	0	7	8
39	R:R:I135	R:R:R139	24.4348	6.26	No	No	4	9	9
40	R:R:R139	R:R:Y229	23.4872	6.17	No	Yes	4	9	9
41	R:R:Y229	R:R:Y370	23.4403	4.96	Yes	Yes	4	9	9
42	R:R:E138	R:R:F79	24.9253	5.83	Yes	Yes	0	9	8
43	R:R:E138	R:R:Q153	10.3222	8.92	Yes	Yes	3	9	7
44	R:R:L315	R:R:Y229	36.8027	9.38	No	Yes	0	8	9
45	R:R:I232	R:R:L315	19.6733	2.85	No	No	0	9	8
46	R:R:I232	R:R:Y140	15.3846	3.63	No	No	0	9	8
47	R:R:E138	R:R:W152	10.2284	6.54	Yes	Yes	3	9	5
48	R:R:K145	R:R:S149	11.5453	1.53	No	Yes	0	6	8
49	R:R:W209	R:R:Y176	11.1956	10.61	No	Yes	0	8	7
50	R:R:F212	R:R:W209	17.0415	8.02	No	No	0	5	8
51	R:R:F212	R:R:L213	17.8152	4.87	No	No	0	5	7
52	R:R:L315	R:R:S233	15.2635	4.5	No	No	0	8	6
53	R:R:I312	R:R:S233	13.0888	6.19	No	No	0	8	6
54	R:R:I312	R:R:Y237	10.9181	3.63	No	No	0	8	6
55	R:R:I318	R:R:Y370	18.0633	6.04	No	Yes	4	9	9
56	R:R:I318	R:R:I369	17.4537	5.89	No	No	0	9	9
57	R:R:I329	R:R:N333	25.2594	7.08	No	No	0	7	7
58	R:R:I329	R:R:S359	21.7346	4.64	No	No	0	7	7
59	R:R:S169	R:R:V127	51.9431	4.85	No	Yes	0	8	8
60	R:R:C94	R:R:Y360	14.2377	8.06	No	Yes	0	7	7
61	R:R:L213	R:R:L217	18.4287	6.92	No	No	0	7	7

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?2	R:R:P101	5.89	1	Yes	No	0	5	0	1
L:L:?2	R:R:F107	5.24	1	Yes	Yes	0	8	0	1
L:L:?2	R:R:F185	5.24	1	Yes	No	0	4	0	1
L:L:?2	R:R:M195	16.22	1	Yes	No	0	4	0	1
L:L:?2	R:R:R197	13.94	1	Yes	No	0	4	0	1
L:L:M3	R:R:E344	5.41	1	Yes	Yes	0	1	0	1
L:L:M3	R:R:S348	4.6	1	Yes	No	0	5	0	1
L:L:G4	R:R:R197	4.5	1	No	No	0	4	0	1
L:L:G4	R:R:R336	4.5	1	No	Yes	0	4	0	1
L:L:G4	R:R:E344	8.19	1	No	Yes	0	1	0	1
L:L:W5	R:R:N333	5.65	0	Yes	No	0	7	0	1
L:L:W5	R:R:R336	15.99	0	Yes	Yes	0	4	0	1
L:L:W5	R:R:A343	3.89	0	Yes	No	0	4	0	1
L:L:W5	R:R:L347	4.56	0	Yes	No	0	5	0	1
L:L:W5	R:R:I352	17.62	0	Yes	No	0	5	0	1
L:L:M6	R:R:N98	7.01	1	No	Yes	0	7	0	1
L:L:M6	R:R:M121	4.33	1	No	Yes	0	7	0	1
L:L:M6	R:R:C196	4.86	1	No	No	0	9	0	1
L:L:D7	R:R:Y176	9.2	0	No	Yes	0	7	0	1
L:L:D7	R:R:H210	5.04	0	No	No	0	6	0	1
L:L:D7	R:R:N333	4.04	0	No	No	0	7	0	1
L:L:F8	R:R:V125	7.87	0	No	No	0	7	0	1
L:L:F8	R:R:F330	5.36	0	No	Yes	0	7	0	1
L:L:?9	R:R:N98	10.2	0	No	Yes	0	7	0	1
L:L:?9	R:R:L356	6.85	0	No	No	0	6	0	1
R:R:C94	R:R:L90	4.76	0	No	Yes	7	8	2	2
R:R:L90	R:R:V125	5.96	0	Yes	No	8	7	2	1
R:R:C94	R:R:M121	8.1	0	No	Yes	7	7	2	1
R:R:C94	R:R:Y360	8.06	0	No	Yes	7	7	2	2
R:R:M121	R:R:N98	4.21	1	Yes	Yes	7	7	1	1
R:R:N98	R:R:Y360	9.3	1	Yes	Yes	7	7	1	2
R:R:F107	R:R:P101	5.78	1	Yes	No	8	5	1	1
R:R:F107	R:R:F109	8.57	1	Yes	Yes	8	6	1	2
R:R:C114	R:R:F107	5.59	1	No	Yes	9	8	2	1
R:R:F107	R:R:L182	4.87	1	Yes	Yes	8	5	1	2
R:R:C196	R:R:F107	11.17	1	No	Yes	9	8	1	1
R:R:C114	R:R:C196	7.28	1	No	No	9	9	2	1
R:R:M121	R:R:T118	4.52	1	Yes	No	7	6	1	2
R:R:T118	R:R:Y176	6.24	0	No	Yes	6	7	2	1
R:R:V125	R:R:W326	6.13	0	No	Yes	7	8	1	2
R:R:M173	R:R:Y176	4.79	0	No	Yes	8	7	2	1
R:R:F198	R:R:Y176	20.63	0	No	Yes	5	7	2	1
R:R:W209	R:R:Y176	10.61	0	No	Yes	8	7	2	1
R:R:A193	R:R:F185	8.32	0	No	No	3	4	2	1
R:R:F185	R:R:M195	12.44	1	No	No	4	4	1	1
R:R:M195	R:R:R197	4.96	1	No	No	4	4	1	1
R:R:H210	R:R:Q206	9.89	0	No	No	6	5	1	2
R:R:A337	R:R:H210	8.78	0	No	No	6	6	2	1
R:R:F218	R:R:L214	4.87	2	Yes	Yes	8	7	2	2
R:R:F330	R:R:L214	8.53	2	Yes	Yes	7	7	1	2
R:R:F330	R:R:L217	4.87	2	Yes	No	7	7	1	2
R:R:F218	R:R:W326	4.01	2	Yes	Yes	8	8	2	2
R:R:F218	R:R:F330	11.79	2	Yes	Yes	8	7	2	1
R:R:F330	R:R:W326	6.01	2	Yes	Yes	7	8	1	2
R:R:I329	R:R:N333	7.08	0	No	No	7	7	2	1
R:R:I329	R:R:L356	4.28	0	No	No	7	6	2	1
R:R:A343	R:R:W335	7.78	0	No	Yes	4	5	1	2
R:R:L347	R:R:W335	4.56	0	No	Yes	5	5	1	2
R:R:R336	R:R:T340	3.88	1	Yes	No	4	2	1	2
R:R:E344	R:R:R336	4.65	1	Yes	Yes	1	4	1	1
R:R:E344	R:R:T340	7.06	1	Yes	No	1	2	1	2
R:R:I352	R:R:I355	4.42	0	No	No	5	6	1	2
R:R:L356	R:R:Y360	8.21	0	No	Yes	6	7	1	2
R:R:G349	R:R:S348	1.86	0	No	No	3	5	2	1
R:R:A332	R:R:I352	1.62	0	No	No	5	5	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	9BKK_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.77
Number of Linked Nodes	271
Number of Links	315
Number of Hubs	39
Number of Links mediated by Hubs	159
Number of Communities	9
Number of Nodes involved in Communities	53
Number of Links involved in Communities	72

Path Summary
Number Of Nodes in MetaPath	62
Number Of Links MetaPath	61
Number of Shortest Paths	86707
Length Of Smallest Path	3
Average Path Length	16.1037
Length of Longest Path	32
Minimum Path Strength	1.24
Average Path Strength	6.21266
Maximum Path Strength	16.97
Minimum Path Correlation	0.7
Average Path Correlation	0.931265
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	3.84615
Average % Of Corr. Nodes	46.6495
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	33.7213
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process	• cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • cell communication • cholecystokinin signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • developmental process • multicellular organismal process • head development • forebrain development • animal organ development • brain development • nervous system development • multicellular organism development • central nervous system development • anatomical structure development • system development • regulation of localization • regulation of hormone secretion • transport • hormone secretion • localization • regulation of secretion by cell • secretion by cell • signal release • regulation of biological quality • regulation of signaling • regulation of transport • secretion • regulation of hormone levels • export from cell • cell-cell signaling • establishment of localization • regulation of secretion • regulation of cell communication • hormone transport • phospholipase C-activating G protein-coupled receptor signaling pathway • neuron migration • cellular developmental process • generation of neurons • neurogenesis • cell differentiation • cell migration • cell motility • cellular response to endogenous stimulus • cellular response to chemical stimulus • response to hormone • response to endogenous stimulus • response to chemical • cellular response to hormone stimulus • axonogenesis • cell projection organization • plasma membrane bounded cell projection morphogenesis • cell development • neuron projection development • cell morphogenesis • cellular component organization • cell projection morphogenesis • neuron differentiation • neuron projection morphogenesis • cellular component organization or biogenesis • plasma membrane bounded cell projection organization • axon development • cell morphogenesis involved in neuron differentiation • anatomical structure morphogenesis • neuron development • cellular anatomical structure • membrane • intracellular anatomical structure • cytoplasm • cytosol • cell periphery • plasma membrane • membrane-bounded organelle • nucleus • membrane-enclosed lumen • intracellular membrane-bounded organelle • intracellular organelle lumen • intracellular organelle • nucleoplasm
Gene Ontology	Cellular Component	• cellular anatomical structure • membrane • intracellular anatomical structure • cytoplasm • cytosol • cell periphery • plasma membrane • membrane-bounded organelle • nucleus • membrane-enclosed lumen • intracellular membrane-bounded organelle • intracellular organelle lumen • intracellular organelle • nucleoplasm • organelle lumen • organelle • nuclear lumen • hormone activity • protein binding • binding • molecular function activator activity • signaling receptor binding • molecular function regulator activity • signaling receptor regulator activity • receptor ligand activity • signaling receptor activator activity • neuropeptide activity • neuropeptide hormone activity • peptide hormone receptor binding • hormone receptor binding • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • cell communication • cholecystokinin signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • developmental process • multicellular organismal process • neuron migration • cellular developmental process • nervous system development • generation of neurons • neurogenesis • multicellular organism development • cell differentiation • anatomical structure development • cell migration • cell motility • system development • behavior • eating behavior • feeding behavior • axonogenesis • cell projection organization • plasma membrane bounded cell projection morphogenesis • cell development • neuron projection development • cell morphogenesis • cellular component organization • cell projection morphogenesis • neuron differentiation • neuron projection morphogenesis • cellular component organization or biogenesis • plasma membrane bounded cell projection organization • axon development • cell morphogenesis involved in neuron differentiation • anatomical structure morphogenesis • neuron development • digestion • extracellular region • axon • cell projection • neuron projection • plasma membrane bounded cell projection • extracellular space • G-protein beta-subunit binding • fibroblast proliferation • cell population proliferation • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to oxygen-containing compound • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to monoamine stimulus • response to chemical • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • response to hormone • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • extracellular vesicle • extracellular organelle • vesicle • extracellular membrane-bounded organelle • synapse • cell junction • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • camera-type eye development • sensory system development • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • cilium • photoreceptor disc membrane • photoreceptor outer segment • photoreceptor cell cilium • organelle membrane • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome • enzyme regulator activity • cyclase regulator activity • adenylate cyclase regulator activity • mu-type opioid receptor binding • G protein-coupled receptor binding • opioid receptor binding • beta-2 adrenergic receptor binding • adrenergic receptor binding • ionotropic glutamate receptor binding • glutamate receptor binding • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • corticotropin-releasing hormone receptor binding • corticotropin-releasing hormone receptor 1 binding • neuropeptide receptor binding • D1 dopamine receptor binding • dopamine receptor binding • G-protein beta/gamma-subunit complex binding • G protein activity • enzyme activator activity • cyclase activator activity • adenylate cyclase activator activity • cation binding • metal ion binding • insulin-like growth factor receptor binding • skeletal system development • bone development • regulation of body fluid levels • wound healing • homotypic cell-cell adhesion • cell activation • hemostasis • platelet aggregation • blood coagulation • cell adhesion • cell-cell adhesion • response to stress • coagulation • regulation of biological quality • response to wounding • platelet activation • developmental growth • growth • homeostatic process • positive regulation of biological process • adaptive thermogenesis • positive regulation of metabolic process • multicellular organismal-level homeostasis • regulation of cold-induced thermogenesis • cold-induced thermogenesis • temperature homeostasis • positive regulation of cold-induced thermogenesis • positive regulation of multicellular organismal process • metabolic process • regulation of multicellular organismal process • regulation of metabolic process • positive regulation of cellular process • serotonin receptor signaling pathway • adenylate cyclase-activating serotonin receptor signaling pathway • apical part of cell • plasma membrane region • apical plasma membrane
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	TYS
PDB Residues	L:L:?2
Environment Details	Open EMBL-EBI Page
Code	TYS
Name	O-SULFO-L-TYROSINE
Synonyms
Identifier
Formula	C9 H11 N O6 S
Molecular Weight	261.252
SMILES
PubChem	514186
Formal Charge	0
Total Atoms	28
Total Chiral Atoms	1
Total Bonds	28
Total Aromatic Bonds	6


Code	NH2
PDB Residues	L:L:?9
Environment Details	Open EMBL-EBI Page
Code	NH2
Name	AMINO GROUP
Synonyms
Identifier
Formula	H2 N
Molecular Weight	16.023
SMILES
PubChem	123329
Formal Charge	0
Total Atoms	3
Total Chiral Atoms	0
Total Bonds	2
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P32238
Sequence	>9BKK_nogp_Chain_R E W Q P A V Q I L L Y S L I F L L S V L G N T L V I T V L I R N K R M R T V T N I F L L S L A V S D L M L C L F C M P F N L I P N L L K D F I F G S A V C K T T T Y F M G T S V S V S T L N L V A I A L E R Y S A I C K P L Q S R V W Q T K S H A L K V I A A T W C L S F T I M T P Y P I Y S N L V P F T K N N N Q T A N M C R F L L P N D V M Q Q S W H T F L L L L L F F I P G V V M A V A Y G L I S L E L Y Q L M A K K R V I R M L I V I V V L F F L C W M P I F S A N A W R A Y D T A S A E R R L S G T P I S F I L L L S Y T S S C V N P I I Y C F M N K R F R L G F M A T F P Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	7XOU	A	Peptide	Cholecystokinin	CCK_A	Homo sapiens	Cholecystokinin-8	-	Gs/β1/γ2	3.2	2022-07-20	doi.org/10.1038/s41421-022-00420-3
	7XOU (No Gprot)	A	Peptide	Cholecystokinin	CCK_A	Homo sapiens	Cholecystokinin-8	-		3.2	2022-07-20	doi.org/10.1038/s41421-022-00420-3
	7XOV	A	Peptide	Cholecystokinin	CCK_A	Homo sapiens	SR146131	-	Gs/β1/γ2	3	2022-07-20	doi.org/10.1038/s41421-022-00420-3
	7XOV (No Gprot)	A	Peptide	Cholecystokinin	CCK_A	Homo sapiens	SR146131	-		3	2022-07-20	doi.org/10.1038/s41421-022-00420-3
	7EZH	A	Peptide	Cholecystokinin	CCK_A	Homo sapiens	Cholecystokinin-8	-	Gi1/β1/γ2	3.2	2021-08-25	doi.org/10.1038/s41589-021-00841-3
	7EZH (No Gprot)	A	Peptide	Cholecystokinin	CCK_A	Homo sapiens	Cholecystokinin-8	-		3.2	2021-08-25	doi.org/10.1038/s41589-021-00841-3
	7EZK	A	Peptide	Cholecystokinin	CCK_A	Homo sapiens	Cholecystokinin-8	-	chim(NtGi1-Gs)/β1/γ2	3.1	2021-08-25	doi.org/10.1038/s41589-021-00841-3
	7EZK (No Gprot)	A	Peptide	Cholecystokinin	CCK_A	Homo sapiens	Cholecystokinin-8	-		3.1	2021-08-25	doi.org/10.1038/s41589-021-00841-3
	7EZM	A	Peptide	Cholecystokinin	CCK_A	Homo sapiens	Cholecystokinin-8	-	chim(NtGsL-Gq)/β1/γ2	2.9	2021-08-25	doi.org/10.1038/s41589-021-00841-3
	7EZM (No Gprot)	A	Peptide	Cholecystokinin	CCK_A	Homo sapiens	Cholecystokinin-8	-		2.9	2021-08-25	doi.org/10.1038/s41589-021-00841-3
	7F8U	A	Peptide	Cholecystokinin	CCK_A	Homo sapiens	Lintitript	-	-	2.8	2021-10-13	doi.org/10.1038/s41589-021-00866-8
	7F8Y	A	Peptide	Cholecystokinin	CCK_A	Homo sapiens	Devazepide	-	-	2.5	2021-10-13	doi.org/10.1038/s41589-021-00866-8
	7F8X	A	Peptide	Cholecystokinin	CCK_A	Homo sapiens	NN9056	-	-	3	2021-12-29	doi.org/10.1038/s41589-021-00866-8
	7MBX	A	Peptide	Cholecystokinin	CCK_A	Homo sapiens	Cholecystokinin-8	-	Gs/β1/γ1	1.95	2021-05-26	doi.org/10.1371/journal.pbio.3001295
	7MBX (No Gprot)	A	Peptide	Cholecystokinin	CCK_A	Homo sapiens	Cholecystokinin-8	-		1.95	2021-05-26	doi.org/10.1371/journal.pbio.3001295
	7MBY	A	Peptide	Cholecystokinin	CCK_A	Homo sapiens	Cholecystokinin-8	-	chim(NtGi1L-Gs-CtGq)/β1/γ2	2.44	2021-05-26	doi.org/10.1371/journal.pbio.3001295
	7MBY (No Gprot)	A	Peptide	Cholecystokinin	CCK_A	Homo sapiens	Cholecystokinin-8	-		2.44	2021-05-26	doi.org/10.1371/journal.pbio.3001295
	9BKJ	A	Peptide	Cholecystokinin	CCK_A	Homo sapiens	Cholecystokinin-8	-	chim(NtGi1-Gs-CtGq)/β1/γ2	2.59	2024-05-22	doi.org/10.1371/journal.pbio.3002673
	9BKJ (No Gprot)	A	Peptide	Cholecystokinin	CCK_A	Homo sapiens	Cholecystokinin-8	-		2.59	2024-05-22	doi.org/10.1371/journal.pbio.3002673
	9BKK	A	Peptide	Cholecystokinin	CCK_A	Homo sapiens	Cholecystokinin-8	-	chim(NtGi1-Gs-CtGq)/β1/γ2	2.51	2024-05-22	doi.org/10.1371/journal.pbio.3002673
	9BKK (No Gprot)	A	Peptide	Cholecystokinin	CCK_A	Homo sapiens	Cholecystokinin-8	-		2.51	2024-05-22	doi.org/10.1371/journal.pbio.3002673

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