psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:V83	13.06	Yes	No	1	0	6
2	L:L:?1	R:R:Y86	9.25	Yes	Yes	0	0	5
3	L:L:?1	R:R:L104	13.35	Yes	No	0	0	5
4	L:L:?1	R:R:F107	16.02	Yes	Yes	1	0	6
5	L:L:?1	R:R:R111	8.52	Yes	Yes	0	0	7
6	L:L:?1	R:R:C177	4.17	Yes	No	1	0	9
7	L:L:?1	R:R:F180	6.41	Yes	Yes	1	0	4
8	L:L:?1	R:R:L280	8.49	Yes	No	1	0	5
9	L:L:?1	R:R:Y284	8.22	Yes	No	0	0	7
10	R:R:E12	R:R:N17	17.09	No	No	0	4	6
11	R:R:I13	R:R:I169	10.3	No	No	0	4	1
12	R:R:K16	R:R:T185	4.5	No	No	0	4	4
13	R:R:C18	R:R:C183	7.28	No	No	0	8	1
14	R:R:C18	R:R:T263	3.38	No	No	0	8	3
15	R:R:C19	R:R:F21	5.59	No	No	0	3	3
16	R:R:C19	R:R:C266	7.28	No	No	0	3	6
17	R:R:F21	R:R:Y269	6.19	No	Yes	0	3	4
18	R:R:D273	R:R:F21	7.17	No	No	0	4	3
19	R:R:R22	R:R:S91	9.22	No	No	4	5	4
20	R:R:A174	R:R:R22	6.91	No	No	4	3	5
21	R:R:R22	R:R:V176	3.92	No	No	0	5	1
22	R:R:D23	R:R:F25	3.58	No	No	5	5	5
23	R:R:D23	R:R:L274	8.14	No	No	5	5	3
24	R:R:F25	R:R:V29	3.93	No	No	0	5	4
25	R:R:F25	R:R:L274	4.87	No	No	5	5	3
26	R:R:I26	R:R:L30	8.56	No	Yes	6	4	6
27	R:R:I26	R:R:Y87	13.3	No	No	6	4	5
28	R:R:K28	R:R:V29	3.04	No	No	0	3	4
29	R:R:L30	R:R:Y87	5.86	Yes	No	6	6	5
30	R:R:P31	R:R:P32	5.84	No	No	0	6	4
31	R:R:E37	R:R:V33	4.28	No	No	0	7	6
32	R:R:L34	R:R:L80	9.69	No	No	0	8	8
33	R:R:L34	R:R:M84	2.83	No	Yes	0	8	7
34	R:R:F40	R:R:L36	8.53	No	No	0	5	4
35	R:R:E37	R:R:M285	5.41	No	No	0	7	5
36	R:R:E37	R:R:M288	4.06	No	No	0	7	6
37	R:R:F38	R:R:L42	6.09	Yes	Yes	2	6	6
38	R:R:F38	R:R:I77	3.77	Yes	Yes	2	6	5
39	R:R:F38	R:R:L80	3.65	Yes	No	0	6	8
40	R:R:F38	R:R:P81	10.11	Yes	No	2	6	9
41	R:R:F38	R:R:M84	6.22	Yes	Yes	2	6	7
42	R:R:F40	R:R:M288	6.22	No	No	0	5	6
43	R:R:G41	R:R:I77	5.29	No	Yes	0	8	5
44	R:R:F74	R:R:L42	3.65	No	Yes	2	7	6
45	R:R:I77	R:R:L42	4.28	Yes	Yes	2	5	6
46	R:R:I78	R:R:L42	2.85	No	Yes	2	4	6
47	R:R:G44	R:R:P291	4.06	No	No	0	7	9
48	R:R:D73	R:R:N45	4.04	Yes	Yes	0	9	9
49	R:R:F74	R:R:N45	6.04	No	Yes	0	7	9
50	R:R:I77	R:R:N45	2.83	Yes	Yes	0	5	9
51	R:R:I51	R:R:L47	2.85	Yes	No	0	7	5
52	R:R:F67	R:R:L49	3.65	No	No	0	6	7
53	R:R:F54	R:R:W50	7.02	No	No	0	4	4
54	R:R:H55	R:R:W50	6.35	No	No	0	5	4
55	R:R:F52	R:R:I51	3.77	No	Yes	0	7	7
56	R:R:I51	R:R:L56	2.85	Yes	No	0	7	6
57	R:R:F301	R:R:I51	3.77	No	Yes	0	8	7
58	R:R:F52	R:R:R63	5.34	No	No	0	7	7
59	R:R:F52	R:R:Y295	7.22	No	Yes	0	7	5
60	R:R:C53	R:R:F54	16.76	No	No	0	2	4
61	R:R:F67	R:R:W59	8.02	No	No	0	6	6
62	R:R:I139	R:R:S61	4.64	No	No	0	7	7
63	R:R:A144	R:R:S61	3.42	No	No	0	8	7
64	R:R:D124	R:R:S62	2.94	No	No	0	8	8
65	R:R:R63	R:R:S300	7.91	No	No	0	7	6
66	R:R:I64	R:R:N141	5.66	No	No	0	6	3
67	R:R:A144	R:R:I64	4.87	No	No	0	8	6
68	R:R:F65	R:R:V120	6.55	No	No	0	6	6
69	R:R:F65	R:R:I147	5.02	No	No	0	6	4
70	R:R:L66	R:R:V121	2.98	No	No	0	8	8
71	R:R:L66	R:R:Y295	8.21	No	Yes	0	8	5
72	R:R:F67	R:R:V71	5.24	No	No	0	6	5
73	R:R:F117	R:R:N68	12.08	Yes	No	3	7	9
74	R:R:N68	R:R:S148	7.45	No	No	0	9	6
75	R:R:N68	R:R:W152	4.52	No	Yes	3	9	9
76	R:R:L69	R:R:S114	3	Yes	No	0	9	9
77	R:R:F117	R:R:L69	6.09	Yes	Yes	0	7	9
78	R:R:L118	R:R:L69	4.15	No	Yes	0	8	9
79	R:R:D290	R:R:L69	4.07	No	Yes	0	9	9
80	R:R:L69	R:R:Y295	4.69	Yes	Yes	0	9	5
81	R:R:A70	R:R:Y295	5.34	No	Yes	0	8	5
82	R:R:L75	R:R:V71	2.98	No	No	0	6	5
83	R:R:D73	R:R:S114	4.42	Yes	No	0	9	9
84	R:R:D73	R:R:S287	7.36	Yes	No	0	9	8
85	R:R:D290	R:R:D73	7.98	No	Yes	0	9	9
86	R:R:F74	R:R:I78	11.3	No	No	2	7	4
87	R:R:L75	R:R:N110	6.87	No	No	0	6	8
88	R:R:L76	R:R:N110	6.87	No	No	0	6	8
89	R:R:I77	R:R:S287	4.64	Yes	No	0	5	8
90	R:R:C79	R:R:M106	3.24	No	No	0	6	5
91	R:R:C79	R:R:F107	4.19	No	Yes	0	6	6
92	R:R:M84	R:R:P81	3.35	Yes	No	2	7	9
93	R:R:F107	R:R:V83	5.24	Yes	No	1	6	6
94	R:R:D85	R:R:F95	5.97	No	No	0	4	7
95	R:R:Y86	R:R:Y87	6.95	Yes	No	0	5	5
96	R:R:W93	R:R:Y86	7.72	Yes	Yes	0	9	5
97	R:R:V176	R:R:Y86	3.79	No	Yes	0	1	5
98	R:R:K94	R:R:R89	3.71	No	No	0	3	4
99	R:R:D92	R:R:S91	5.89	No	No	0	3	4
100	R:R:A174	R:R:S91	3.42	No	No	4	3	4
101	R:R:C100	R:R:W93	6.53	No	Yes	1	9	9
102	R:R:C177	R:R:W93	16.98	No	Yes	1	9	9
103	R:R:F95	R:R:P99	2.89	No	No	0	7	5
104	R:R:G96	R:R:P99	4.06	No	No	0	8	5
105	R:R:D97	R:R:R101	13.1	No	No	0	3	7
106	R:R:D97	R:R:L168	9.5	No	No	0	3	4
107	R:R:I98	R:R:P99	3.39	No	No	0	1	5
108	R:R:I98	R:R:R101	5.01	No	No	0	1	7
109	R:R:C100	R:R:C177	7.28	No	No	1	9	9
110	R:R:L167	R:R:R101	4.86	No	No	0	4	7
111	R:R:F107	R:R:V103	5.24	Yes	No	0	6	5
112	R:R:L104	R:R:S179	3	No	No	0	5	5
113	R:R:F105	R:R:M109	4.98	No	Yes	3	5	5
114	R:R:F105	R:R:T159	7.78	No	No	3	5	6
115	R:R:F105	R:R:L163	14.61	No	No	0	5	4
116	R:R:M109	R:R:W152	4.65	Yes	Yes	3	5	9
117	R:R:M109	R:R:T155	3.01	Yes	No	0	5	7
118	R:R:M109	R:R:V156	3.04	Yes	No	0	5	4
119	R:R:M109	R:R:T159	9.03	Yes	No	3	5	6
120	R:R:F193	R:R:R111	3.21	No	Yes	0	5	7
121	R:R:F244	R:R:R111	3.21	No	Yes	0	9	7
122	R:R:R111	R:R:T283	5.17	Yes	No	0	7	8
123	R:R:I116	R:R:Q112	5.49	No	Yes	0	5	7
124	R:R:Q112	R:R:T155	7.09	Yes	No	0	7	7
125	R:R:L158	R:R:Q112	7.99	No	Yes	7	4	7
126	R:R:M192	R:R:Q112	5.44	No	Yes	7	5	7
127	R:R:E196	R:R:Q112	10.19	No	Yes	0	6	7
128	R:R:F117	R:R:G113	3.01	Yes	No	0	7	6
129	R:R:G113	R:R:T155	3.64	No	No	0	6	7
130	R:R:I115	R:R:P200	3.39	No	No	0	8	9
131	R:R:F244	R:R:I115	6.28	No	No	0	9	8
132	R:R:I116	R:R:L151	5.71	No	No	0	5	7
133	R:R:F117	R:R:L151	4.87	Yes	No	0	7	7
134	R:R:F117	R:R:W152	12.03	Yes	Yes	3	7	9
135	R:R:L118	R:R:Y294	5.86	No	No	0	8	9
136	R:R:P200	R:R:T119	3.5	No	No	0	9	7
137	R:R:I203	R:R:T119	4.56	No	No	0	6	7
138	R:R:I204	R:R:T119	3.04	Yes	No	0	8	7
139	R:R:R125	R:R:V121	5.23	No	No	0	9	8
140	R:R:D124	R:R:R128	10.72	No	No	0	8	8
141	R:R:R125	R:R:Y294	4.12	No	No	0	9	9
142	R:R:F127	R:R:Y126	5.16	Yes	Yes	0	5	8
143	R:R:V130	R:R:Y126	10.09	No	Yes	0	7	8
144	R:R:C207	R:R:Y126	9.41	No	Yes	0	6	8
145	R:R:R210	R:R:Y126	4.12	No	Yes	0	4	8
146	R:R:I211	R:R:Y126	3.63	No	Yes	0	8	8
147	R:R:F127	R:R:H134	5.66	Yes	No	0	5	5
148	R:R:F127	R:R:L136	7.31	Yes	No	0	5	4
149	R:R:N137	R:R:R128	4.82	No	No	0	4	8
150	R:R:I211	R:R:V129	7.68	No	No	0	8	8
151	R:R:H131	R:R:V130	6.92	No	No	0	6	7
152	R:R:S214	R:R:V130	3.23	No	No	0	5	7
153	R:R:H133	R:R:P132	4.58	No	No	0	5	8
154	R:R:I139	R:R:T143	7.6	No	No	0	7	3
155	R:R:S140	R:R:T143	4.8	No	No	0	6	3
156	R:R:I146	R:R:W142	11.74	No	No	0	3	4
157	R:R:I147	R:R:L151	2.85	No	No	0	4	7
158	R:R:I154	R:R:L150	2.85	No	No	0	4	3
159	R:R:I154	R:R:L158	2.85	No	No	0	4	4
160	R:R:L158	R:R:M192	4.24	No	No	7	4	5
161	R:R:L163	R:R:V160	2.98	No	No	0	4	4
162	R:R:H161	R:R:L162	3.86	No	Yes	1	8	3
163	R:R:H161	R:R:K165	13.1	No	No	1	8	4
164	R:R:H161	R:R:R187	13.54	No	No	0	8	1
165	R:R:K165	R:R:L162	4.23	No	Yes	1	4	3
166	R:R:L162	R:R:S179	3	Yes	No	1	3	5
167	R:R:H189	R:R:L162	9	No	Yes	1	5	3
168	R:R:K165	R:R:L167	2.82	No	No	0	4	4
169	R:R:I169	R:R:V176	6.14	No	No	0	1	1
170	R:R:N175	R:R:Q170	11.88	No	No	0	3	2
171	R:R:F277	R:R:I178	3.77	No	No	0	5	3
172	R:R:H189	R:R:S179	9.76	No	No	1	5	5
173	R:R:F180	R:R:H189	6.79	Yes	No	1	4	5
174	R:R:F180	R:R:F193	5.36	Yes	No	0	4	5
175	R:R:F180	R:R:R251	4.28	Yes	Yes	1	4	6
176	R:R:F180	R:R:F276	10.72	Yes	Yes	1	4	4
177	R:R:F180	R:R:L280	4.87	Yes	No	1	4	5
178	R:R:I182	R:R:Y269	3.63	No	Yes	0	2	4
179	R:R:D273	R:R:I182	9.8	No	No	0	4	2
180	R:R:C183	R:R:T185	3.38	No	No	0	1	4
181	R:R:H184	R:R:L258	5.14	No	No	0	3	3
182	R:R:M192	R:R:W188	3.49	No	No	0	5	4
183	R:R:E190	R:R:R251	6.98	No	Yes	1	4	6
184	R:R:E190	R:R:F255	12.83	No	No	1	4	5
185	R:R:F193	R:R:S247	3.96	No	No	0	5	6
186	R:R:I252	R:R:L194	2.85	No	No	0	6	4
187	R:R:F197	R:R:F198	7.5	Yes	No	0	8	4
188	R:R:F197	R:R:L201	3.65	Yes	Yes	0	8	6
189	R:R:F197	R:R:L245	3.65	Yes	No	0	8	5
190	R:R:F197	R:R:V248	7.87	Yes	No	0	8	8
191	R:R:L199	R:R:P200	3.28	No	No	0	5	9
192	R:R:I203	R:R:L199	2.85	No	No	0	6	5
193	R:R:L201	R:R:L205	6.92	Yes	No	0	6	4
194	R:R:F240	R:R:L201	3.65	No	Yes	0	9	6
195	R:R:F240	R:R:I204	3.77	No	Yes	0	9	8
196	R:R:F206	R:R:R210	6.41	No	No	0	3	4
197	R:R:I233	R:R:S208	3.1	No	No	0	7	8
198	R:R:R210	R:R:W213	3	No	No	0	4	4
199	R:R:I212	R:R:I230	2.94	No	Yes	8	5	5
200	R:R:Q217	R:R:W213	21.9	No	No	0	5	4
201	R:R:Q217	R:R:S214	2.89	No	No	0	5	5
202	R:R:I226	R:R:L215	5.71	No	No	0	7	8
203	R:R:I230	R:R:L215	2.85	Yes	No	0	5	8
204	R:R:M220	R:R:R218	6.2	No	No	0	3	6
205	R:R:H223	R:R:K225	6.55	No	No	0	3	5
206	R:R:F232	R:R:R228	14.97	No	No	0	7	7
207	R:R:P299	R:R:R228	10.09	No	No	0	5	7
208	R:R:F232	R:R:T231	3.89	No	No	0	7	6
209	R:R:F232	R:R:S297	9.25	No	No	0	7	6
210	R:R:V236	R:R:V293	3.21	No	No	0	7	7
211	R:R:V236	R:R:Y294	11.36	No	No	0	7	9
212	R:R:C243	R:R:M285	3.24	Yes	No	0	8	5
213	R:R:C243	R:R:N286	3.15	Yes	No	0	8	9
214	R:R:F244	R:R:N286	7.25	No	No	0	9	9
215	R:R:L245	R:R:P246	3.28	No	No	0	5	9
216	R:R:L245	R:R:V249	2.98	No	No	0	5	5
217	R:R:P246	R:R:T279	3.5	No	No	0	9	6
218	R:R:F282	R:R:P246	5.78	No	No	0	7	9
219	R:R:S247	R:R:T279	3.2	No	No	0	6	6
220	R:R:I254	R:R:V250	3.07	No	No	1	5	4
221	R:R:F276	R:R:V250	5.24	Yes	No	1	4	4
222	R:R:T279	R:R:V250	4.76	No	No	0	6	4
223	R:R:F255	R:R:R251	5.34	No	Yes	1	5	6
224	R:R:F276	R:R:R251	7.48	Yes	Yes	1	4	6
225	R:R:H253	R:R:L257	9	No	No	0	5	2
226	R:R:I254	R:R:V272	3.07	No	No	0	5	4
227	R:R:F276	R:R:I254	3.77	Yes	No	1	4	5
228	R:R:L257	R:R:V268	2.98	No	No	0	2	1
229	R:R:L257	R:R:V272	2.98	No	No	0	2	4
230	R:R:L258	R:R:Y269	5.86	No	Yes	0	3	4
231	R:R:Q264	R:R:T263	4.25	No	No	0	1	3
232	R:R:T283	R:R:Y284	7.49	No	No	0	8	7
233	R:R:N286	R:R:S287	4.47	No	No	0	9	8
234	R:R:L289	R:R:M288	4.24	No	No	0	7	6
235	R:R:F296	R:R:P291	4.33	No	No	0	7	9
236	R:R:V292	R:R:V293	3.21	No	No	0	6	7
237	R:R:S298	R:R:S300	3.26	No	No	0	8	6
238	R:R:M109	R:R:N110	2.8	Yes	No	0	5	8
239	R:R:P291	R:R:Y295	2.78	No	Yes	0	9	5
240	R:R:A27	R:R:R90	2.77	No	No	0	4	3
241	R:R:F282	R:R:S281	2.64	No	No	0	7	5
242	R:R:E267	R:R:N265	2.63	No	No	0	1	4
243	R:R:F127	R:R:V123	2.62	Yes	No	0	5	6
244	R:R:A72	R:R:W152	2.59	No	Yes	0	8	9
245	R:R:S261	R:R:Y269	2.54	No	Yes	0	4	4
246	R:R:V272	R:R:Y269	2.52	No	Yes	0	4	4
247	R:R:F277	R:R:I26	2.51	No	No	0	5	4
248	R:R:F38	R:R:I39	2.51	Yes	No	0	6	5
249	R:R:F95	R:R:K94	2.48	No	No	0	7	3
250	R:R:T260	R:R:W256	2.43	No	No	0	1	4
251	R:R:D24	R:R:R90	2.38	No	No	0	4	3
252	R:R:I64	R:R:W59	2.35	No	No	0	6	6
253	R:R:G262	R:R:S261	1.86	No	No	0	3	4
254	R:R:G157	R:R:V160	1.84	No	No	0	4	4
255	R:R:P299	R:R:S298	1.78	No	No	0	5	8
256	R:R:P31	R:R:V88	1.77	No	No	0	6	3
257	R:R:G35	R:R:M84	1.75	No	Yes	0	5	7
258	R:R:G44	R:R:L43	1.71	No	No	0	7	4
259	R:R:G202	R:R:L201	1.71	No	Yes	0	3	6
260	R:R:A237	R:R:S208	1.71	No	No	0	7	8
261	R:R:C243	R:R:V239	1.71	Yes	No	0	8	7
262	R:R:G46	R:R:N45	1.7	No	Yes	0	1	9
263	R:R:G172	R:R:N171	1.7	No	No	0	3	2
264	R:R:A108	R:R:T159	1.68	No	No	0	5	6
265	R:R:L30	R:R:P31	1.64	Yes	No	0	6	6
266	R:R:C207	R:R:I203	1.64	No	No	0	6	6
267	R:R:C243	R:R:I242	1.64	Yes	No	0	8	5
268	R:R:A122	R:R:I204	1.62	No	Yes	0	9	8
269	R:R:A237	R:R:M234	1.61	No	No	0	7	5
270	R:R:V235	R:R:V239	1.6	No	No	0	5	7
271	R:R:V235	R:R:V293	1.6	No	No	0	5	7
272	R:R:S261	R:R:T260	1.6	No	No	0	4	1
273	R:R:I13	R:R:S181	1.55	No	No	0	4	5
274	R:R:I204	R:R:S208	1.55	Yes	No	0	8	8
275	R:R:I13	R:R:V20	1.54	No	No	0	4	2
276	R:R:K60	R:R:S58	1.53	No	No	0	7	6
277	R:R:H131	R:R:P132	1.53	No	No	0	6	8
278	R:R:I230	R:R:T231	1.52	Yes	No	0	5	6
279	R:R:L66	R:R:S62	1.5	No	No	0	8	8
280	R:R:L30	R:R:V29	1.49	Yes	No	0	6	4
281	R:R:L194	R:R:V248	1.49	No	No	0	4	8
282	R:R:L201	R:R:V241	1.49	Yes	No	0	6	4
283	R:R:N171	R:R:V20	1.48	No	No	0	2	2
284	R:R:N265	R:R:V268	1.48	No	No	0	4	1
285	R:R:L258	R:R:T263	1.47	No	No	0	3	3
286	R:R:A135	R:R:H134	1.46	No	No	0	5	5
287	R:R:I278	R:R:L30	1.43	No	Yes	0	5	6
288	R:R:G153	R:R:W152	1.41	No	Yes	0	4	9
289	R:R:A48	R:R:F296	1.39	No	No	0	8	7
290	R:R:A191	R:R:F186	1.39	No	No	0	2	3
291	R:R:H259	R:R:T260	1.37	No	No	0	2	1
292	R:R:D23	R:R:D24	1.33	No	No	0	5	4
293	R:R:H55	R:R:I51	1.33	No	Yes	0	5	7
294	R:R:E196	R:R:L195	1.33	No	No	0	6	5
295	R:R:I212	R:R:R216	1.25	No	No	8	5	4
296	R:R:I230	R:R:R216	1.25	Yes	No	8	5	4
297	R:R:S140	R:R:W142	1.24	No	No	0	6	4
298	R:R:D221	R:R:R222	1.19	No	No	0	3	4
299	R:R:F82	R:R:W93	1	No	Yes	0	6	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:?1	9.72111	9	1	0
2	R:R:L30	3.796	5	6	6
3	R:R:F38	5.39167	6	2	6
4	R:R:L42	4.2175	4	2	6
5	R:R:N45	3.6525	4	0	9
6	R:R:I51	2.914	5	0	7
7	R:R:L69	4.4	5	0	9
8	R:R:D73	5.95	4	0	9
9	R:R:I77	4.162	5	2	5
10	R:R:M84	3.5375	4	2	7
11	R:R:Y86	6.9275	4	0	5
12	R:R:W93	8.0575	4	1	9
13	R:R:F107	7.6725	4	1	6
14	R:R:M109	4.585	6	3	5
15	R:R:R111	5.0275	4	0	7
16	R:R:Q112	7.24	5	7	7
17	R:R:F117	7.616	5	3	7
18	R:R:Y126	6.482	5	0	8
19	R:R:F127	5.1875	4	0	5
20	R:R:W152	5.04	5	3	9
21	R:R:L162	5.0225	4	1	3
22	R:R:F180	6.405	6	1	4
23	R:R:F197	5.6675	4	0	8
24	R:R:L201	3.484	5	0	6
25	R:R:I204	2.495	4	0	8
26	R:R:I230	2.14	4	8	5
27	R:R:C243	2.435	4	0	8
28	R:R:R251	6.02	4	1	6
29	R:R:Y269	4.148	5	0	4
30	R:R:F276	6.8025	4	1	4
31	R:R:Y295	5.648	5	0	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:Y86	23.8813	9.25	Yes	Yes	0	0	5
2	L:L:?1	R:R:F180	31.8679	6.41	Yes	Yes	1	0	4
3	R:R:F180	R:R:F276	35.0618	10.72	Yes	Yes	1	4	4
4	R:R:F276	R:R:I254	31.236	3.77	Yes	No	1	4	5
5	R:R:I254	R:R:V272	31.4543	3.07	No	No	0	5	4
6	R:R:V272	R:R:Y269	24.3887	2.52	No	Yes	0	4	4
7	R:R:L258	R:R:Y269	10.001	5.86	No	Yes	0	3	4
8	R:R:Y86	R:R:Y87	13.6103	6.95	Yes	No	0	5	5
9	R:R:L30	R:R:Y87	10.5524	5.86	Yes	No	6	6	5
10	L:L:?1	R:R:R111	58.426	8.52	Yes	Yes	0	0	7
11	R:R:F244	R:R:R111	89.8861	3.21	No	Yes	0	9	7
12	R:R:F244	R:R:N286	100	7.25	No	No	0	9	9
13	R:R:C243	R:R:N286	11.1498	3.15	Yes	No	0	8	9
14	R:R:N286	R:R:S287	96.7659	4.47	No	No	0	9	8
15	R:R:I77	R:R:S287	11.5921	4.64	Yes	No	0	5	8
16	R:R:D73	R:R:S287	92.9363	7.36	Yes	No	0	9	8
17	R:R:D73	R:R:S114	48.4978	4.42	Yes	No	0	9	9
18	R:R:L69	R:R:S114	48.1513	3	Yes	No	0	9	9
19	R:R:L69	R:R:Y295	40.0536	4.69	Yes	Yes	0	9	5
20	R:R:D290	R:R:D73	48.5898	7.98	No	Yes	0	9	9
21	R:R:D290	R:R:L69	48.2432	4.07	No	Yes	0	9	9
22	R:R:F52	R:R:Y295	25.6103	7.22	No	Yes	0	7	5
23	R:R:F117	R:R:L69	60.5859	6.09	Yes	Yes	0	7	9
24	R:R:F117	R:R:W152	31.0847	12.03	Yes	Yes	3	7	9
25	R:R:M109	R:R:W152	27.9253	4.65	Yes	Yes	3	5	9
26	R:R:M109	R:R:N110	19.1077	2.8	Yes	No	0	5	8
27	R:R:L75	R:R:N110	16.7602	6.87	No	No	0	6	8
28	R:R:L75	R:R:V71	15.5807	2.98	No	No	0	6	5
29	R:R:F67	R:R:V71	14.3973	5.24	No	No	0	6	5
30	R:R:F67	R:R:W59	12.0172	8.02	No	No	0	6	6
31	R:R:I64	R:R:W59	10.9239	2.35	No	No	0	6	6
32	R:R:F117	R:R:L151	15.1881	4.87	Yes	No	0	7	7
33	L:L:?1	R:R:L104	10.4605	13.35	Yes	No	0	0	5
34	R:R:K165	R:R:L162	22.7918	4.23	No	Yes	1	4	3
35	R:R:K165	R:R:L167	20.9555	2.82	No	No	0	4	4
36	R:R:L167	R:R:R101	19.0694	4.86	No	No	0	4	7
37	R:R:I98	R:R:R101	13.3882	5.01	No	No	0	1	7
38	R:R:I98	R:R:P99	11.4868	3.39	No	No	0	1	5
39	R:R:F180	R:R:H189	20.3064	6.79	Yes	No	1	4	5
40	R:R:H189	R:R:L162	19.0254	9	No	Yes	1	5	3
41	R:R:F117	R:R:G113	11.529	3.01	Yes	No	0	7	6
42	R:R:G113	R:R:T155	10.428	3.64	No	No	0	6	7
43	R:R:F193	R:R:R111	33.3212	3.21	No	Yes	0	5	7
44	R:R:I116	R:R:L151	10.4394	5.71	No	No	0	5	7
45	R:R:F244	R:R:I115	41.3787	6.28	No	No	0	9	8
46	R:R:I115	R:R:P200	40.7391	3.39	No	No	0	8	9
47	R:R:P200	R:R:T119	24.4595	3.5	No	No	0	9	7
48	R:R:I203	R:R:T119	15.8909	4.56	No	No	0	6	7
49	R:R:L199	R:R:P200	15.7281	3.28	No	No	0	5	9
50	R:R:I203	R:R:L199	15.0101	2.85	No	No	0	6	5
51	R:R:C207	R:R:I203	29.3059	1.64	No	No	0	6	6
52	R:R:C207	R:R:Y126	27.7894	9.41	No	Yes	0	6	8
53	R:R:F180	R:R:F193	27.4964	5.36	Yes	No	0	4	5
54	R:R:P246	R:R:T279	10.3916	3.5	No	No	0	9	6
55	R:R:F52	R:R:R63	15.1958	5.34	No	No	0	7	7
56	R:R:R63	R:R:S300	14.091	7.91	No	No	0	7	6
57	R:R:S298	R:R:S300	12.9976	3.26	No	No	0	8	6
58	R:R:P299	R:R:S298	11.7913	1.78	No	No	0	5	8
59	R:R:P299	R:R:R228	10.5716	10.09	No	No	0	5	7

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?1	R:R:V83	13.06	1	Yes	No	0	6	0	1
L:L:?1	R:R:Y86	9.25	1	Yes	Yes	0	5	0	1
L:L:?1	R:R:L104	13.35	1	Yes	No	0	5	0	1
L:L:?1	R:R:F107	16.02	1	Yes	Yes	0	6	0	1
L:L:?1	R:R:R111	8.52	1	Yes	Yes	0	7	0	1
L:L:?1	R:R:C177	4.17	1	Yes	No	0	9	0	1
L:L:?1	R:R:F180	6.41	1	Yes	Yes	0	4	0	1
L:L:?1	R:R:L280	8.49	1	Yes	No	0	5	0	1
L:L:?1	R:R:Y284	8.22	1	Yes	No	0	7	0	1
R:R:C79	R:R:F107	4.19	0	No	Yes	6	6	2	1
R:R:F107	R:R:V83	5.24	1	Yes	No	6	6	1	1
R:R:Y86	R:R:Y87	6.95	0	Yes	No	5	5	1	2
R:R:W93	R:R:Y86	7.72	1	Yes	Yes	9	5	2	1
R:R:V176	R:R:Y86	3.79	0	No	Yes	1	5	2	1
R:R:C100	R:R:W93	6.53	1	No	Yes	9	9	2	2
R:R:C177	R:R:W93	16.98	1	No	Yes	9	9	1	2
R:R:C100	R:R:C177	7.28	1	No	No	9	9	2	1
R:R:F107	R:R:V103	5.24	1	Yes	No	6	5	1	2
R:R:L104	R:R:S179	3	0	No	No	5	5	1	2
R:R:F193	R:R:R111	3.21	0	No	Yes	5	7	2	1
R:R:F244	R:R:R111	3.21	0	No	Yes	9	7	2	1
R:R:R111	R:R:T283	5.17	0	Yes	No	7	8	1	2
R:R:H189	R:R:S179	9.76	1	No	No	5	5	2	2
R:R:F180	R:R:H189	6.79	1	Yes	No	4	5	1	2
R:R:F180	R:R:F193	5.36	1	Yes	No	4	5	1	2
R:R:F180	R:R:R251	4.28	1	Yes	Yes	4	6	1	2
R:R:F180	R:R:F276	10.72	1	Yes	Yes	4	4	1	2
R:R:F180	R:R:L280	4.87	1	Yes	No	4	5	1	1
R:R:F276	R:R:R251	7.48	1	Yes	Yes	4	6	2	2
R:R:T283	R:R:Y284	7.49	0	No	No	8	7	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	9KT6_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	2.82
Number of Linked Nodes	272
Number of Links	299
Number of Hubs	31
Number of Links mediated by Hubs	126
Number of Communities	8
Number of Nodes involved in Communities	47
Number of Links involved in Communities	57

Path Summary
Number Of Nodes in MetaPath	60
Number Of Links MetaPath	59
Number of Shortest Paths	82652
Length Of Smallest Path	3
Average Path Length	15.6186
Length of Longest Path	35
Minimum Path Strength	1.385
Average Path Strength	5.3212
Maximum Path Strength	14.685
Minimum Path Correlation	0.7
Average Path Correlation	0.922933
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	3.7037
Average % Of Corr. Nodes	45.6989
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	35.8686
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process	• cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • G protein-coupled receptor signaling pathway • cellular process • signal transduction • cell communication • negative regulation of catabolic process • lipid catabolic process • catabolic process • regulation of lipid metabolic process • negative regulation of metabolic process • negative regulation of biological process • primary metabolic process • regulation of catabolic process • regulation of lipid catabolic process • regulation of primary metabolic process • negative regulation of cellular process • metabolic process • regulation of metabolic process • negative regulation of lipid metabolic process • negative regulation of lipid catabolic process • lipid metabolic process • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • cellular anatomical structure • cell junction • cell periphery • plasma membrane • membrane • protein binding • binding • G-protein beta-subunit binding • fibroblast proliferation • cell population proliferation • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to oxygen-containing compound • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to monoamine stimulus • response to chemical • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • response to hormone • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • membrane-bounded organelle • extracellular vesicle • extracellular organelle • extracellular region • organelle • extracellular space • vesicle • extracellular membrane-bounded organelle • synapse • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection • photoreceptor cell cilium • organelle membrane • intracellular anatomical structure • cytoplasm • cytosol • vacuolar membrane • lytic vacuole • vacuole • intracellular membrane-bounded organelle • intracellular organelle • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome • D2 dopamine receptor binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • enzyme regulator activity • adenylate cyclase inhibitor activity • cyclase regulator activity • molecular function inhibitor activity • cyclase inhibitor activity • molecular function regulator activity • enzyme inhibitor activity • adenylate cyclase regulator activity • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • cation binding • magnesium ion binding • metal ion binding • GDP binding • G protein-coupled serotonin receptor binding • G-protein beta/gamma-subunit complex binding • G protein activity • neuropeptide signaling pathway • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • response to peptide hormone • cell division • leukocyte migration • immune system process • mononuclear cell migration • lymphocyte migration • cell migration • T cell migration • cell motility • regulation of steroid biosynthetic process • regulation of cholesterol biosynthetic process • regulation of cholesterol metabolic process • steroid metabolic process • sterol metabolic process • positive regulation of biological process • cholesterol metabolic process • lipid biosynthetic process • alcohol metabolic process • positive regulation of metabolic process • regulation of small molecule metabolic process • positive regulation of biosynthetic process • positive regulation of lipid metabolic process • small molecule metabolic process • steroid biosynthetic process • positive regulation of cellular process • regulation of biosynthetic process • secondary alcohol biosynthetic process • regulation of alcohol biosynthetic process • small molecule biosynthetic process • regulation of steroid metabolic process • cholesterol biosynthetic process • positive regulation of cholesterol biosynthetic process • secondary alcohol metabolic process • positive regulation of steroid biosynthetic process • biosynthetic process • sterol biosynthetic process • positive regulation of lipid biosynthetic process • regulation of sterol biosynthetic process • alcohol biosynthetic process • positive regulation of cholesterol metabolic process • positive regulation of steroid metabolic process • regulation of lipid biosynthetic process • positive regulation of small molecule metabolic process • positive regulation of alcohol biosynthetic process • positive regulation of sterol biosynthetic process • cell surface receptor signaling pathway • response to cytokine • response to chemokine • cytokine-mediated signaling pathway • cellular response to chemokine • chemokine-mediated signaling pathway • response to peptide • cellular response to cytokine stimulus • relaxation of smooth muscle • regulation of system process • regulation of muscle system process • muscle system process • relaxation of muscle • positive regulation of relaxation of smooth muscle • positive regulation of relaxation of muscle • positive regulation of multicellular organismal process • regulation of multicellular organismal process • regulation of relaxation of smooth muscle • regulation of relaxation of muscle • negative regulation of protein transport • regulation of localization • establishment of protein localization • nitrogen compound transport • negative regulation of transport • localization • negative regulation of secretion • negative regulation of hormone secretion • negative regulation of secretion by cell • intracellular protein localization • regulation of biological quality • regulation of peptide hormone secretion • negative regulation of peptide hormone secretion • regulation of hormone levels • establishment of protein localization to extracellular region • negative regulation of establishment of protein localization • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • negative regulation of protein secretion • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • transport • negative regulation of signaling • hormone secretion • negative regulation of cell communication • protein localization to extracellular region • negative regulation of peptide secretion • peptide secretion • regulation of secretion by cell • secretion by cell • signal release • negative regulation of protein localization • regulation of signaling • regulation of transport • secretion • regulation of peptide transport • regulation of establishment of protein localization • export from cell • regulation of protein transport • peptide transport • negative regulation of insulin secretion • protein transport • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • hormone transport • regulation of cell communication • insulin secretion • regulation of cytoskeleton organization • regulation of cellular component organization • microtubule cytoskeleton organization • regulation of mitotic spindle organization • mitotic cell cycle • cellular component organization • cell cycle • cellular component organization or biogenesis • regulation of cell cycle • microtubule cytoskeleton organization involved in mitosis • spindle organization • cell cycle process • regulation of cell cycle process • regulation of microtubule-based process • regulation of spindle organization • regulation of organelle organization • mitotic spindle organization • organelle organization • mitotic cell cycle process • microtubule-based process • cytoskeleton organization • regulation of microtubule cytoskeleton organization • positive regulation of protein localization to cell periphery • protein localization to cell periphery • positive regulation of protein localization to cell cortex • regulation of protein localization to cell periphery • regulation of protein localization to cell cortex • positive regulation of protein localization • protein localization to cell cortex • cellular response to forskolin • response to forskolin • midbody • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • nucleolus • intracellular organelle lumen • organelle lumen • membraneless organelle • nuclear lumen • cell cortex • centrosome • microtubule organizing center • cytoskeleton • microtubule cytoskeleton • centriolar satellite • sperm principal piece • 9+2 motile cilium • sperm flagellum • motile cilium • nucleoplasm • Golgi apparatus • endomembrane system • ciliary basal body
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain • Ras-like P-loop GTPases
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain • Ras-like P-loop GTPases
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	P9X
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	P9X
Name	(5~{S})-5-methyl-4-oxidanylidene-5-phenyl-furan-2-carboxylic acid
Synonyms	Acifran
Identifier
Formula	C12 H10 O4
Molecular Weight	218.205
SMILES
PubChem	76969700
Formal Charge	0
Total Atoms	26
Total Chiral Atoms	1
Total Bonds	27
Total Aromatic Bonds	6


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P49019
Sequence	>9KT6_nogp_Chain_R L E I D K K N C C V F R D D F I A K V L P P V L G L E F I F G L L G N G L A L W I F C F H L K S W K S S R I F L F N L A V A D F L L I I C L P F V M D Y Y V R R S D W K F G D I P C R L V L F M F A M N R Q G S I I F L T V V A V D R Y F R V V H P H H A L N K I S N W T A A I I S C L L W G I T V G L T V H L L K K K L L I Q N G T A N V C I S F S I C H T F R W H E A M F L L E F F L P L G I I L F C S A R I I W S L R Q R Q M D R H A K I K R A I T F I M V V A I V F V I C F L P S V V V R I H I F W L L H T S G T Q N C E V Y R S V D L A F F I T L S F T Y M N S M L D P V V Y Y F S S P S F Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8IHJ	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₃	Homo sapiens	Acifran	-	Gi1/β1/γ2	3.07	2023-08-30	doi.org/10.1038/s41467-023-41650-7
	8IHJ (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₃	Homo sapiens	Acifran	-		3.07	2023-08-30	doi.org/10.1038/s41467-023-41650-7
	8IHK	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₃	Homo sapiens	Acifran	-	-	3.21	2023-08-30	doi.org/10.1038/s41467-023-41650-7
	9JKS	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₃	Homo sapiens	PubChem 44250176	-	Gi1/β1/γ2	3.31	2025-10-29	To be published
	9JKS (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₃	Homo sapiens	PubChem 44250176	-		3.31	2025-10-29	To be published
	9JKT	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₃	Homo sapiens	(2R)-2-hydroxy-3-phenylpropanoic acid	-	Gi1/β1/γ2	3.05	2025-10-29	To be published
	9JKT (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₃	Homo sapiens	(2R)-2-hydroxy-3-phenylpropanoic acid	-		3.05	2025-10-29	To be published
	9JKV	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₃	Homo sapiens	PubChem 2736690	-	Gi1/β1/γ2	3.26	2025-10-29	To be published
	9JKV (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₃	Homo sapiens	PubChem 2736690	-		3.26	2025-10-29	To be published
	9JKX	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₃	Homo sapiens	Acifran	-	Gi1/β1/γ2	3.18	2025-10-29	To be published
	9JKX (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₃	Homo sapiens	Acifran	-		3.18	2025-10-29	To be published
	8JEF	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₃	Homo sapiens	PubChem 11367166	-	Gi1/β1/γ2	2.96	2024-12-18	doi.org/10.1016/j.celrep.2024.114895
	8JEF (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₃	Homo sapiens	PubChem 11367166	-		2.96	2024-12-18	doi.org/10.1016/j.celrep.2024.114895
	9KT6	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₃	Homo sapiens	Acifran	-	Gi1/β1/γ2	3.01	2025-12-10	10.1021/acs.jmedchem.4c02567
	9KT6 (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₃	Homo sapiens	Acifran	-		3.01	2025-12-10	10.1021/acs.jmedchem.4c02567
	9JIC	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₃	Homo sapiens	-	-	Gi1/β1/γ2	3.4	2025-12-17	10.1016/j.celrep.2024.114895
	9JIC (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₃	Homo sapiens	-	-		3.4	2025-12-17	10.1016/j.celrep.2024.114895
	9JID	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₃	Homo sapiens	Niacin	-	Gi1/β1/γ2	2.78	2025-12-17	10.1016/j.celrep.2024.114895
	9JID (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₃	Homo sapiens	Niacin	-		2.78	2025-12-17	10.1016/j.celrep.2024.114895

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