psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:L559	R:R:V622	4.47	No	No	0	8	7
2	R:R:I790	R:R:L559	2.85	Yes	No	0	8	8
3	R:R:V622	R:R:W561	12.26	No	No	0	7	5
4	R:R:E563	R:R:P565	14.15	No	No	0	8	6
5	R:R:E563	R:R:T566	7.06	No	No	0	8	7
6	R:R:I567	R:R:T566	4.56	No	No	0	6	7
7	R:R:I790	R:R:T566	3.04	Yes	No	0	8	7
8	R:R:L793	R:R:V569	4.47	No	No	0	8	8
9	R:R:L794	R:R:V569	4.47	No	No	0	7	8
10	R:R:V569	R:R:V797	3.21	No	No	0	8	9
11	R:R:L572	R:R:V797	2.98	No	No	0	3	9
12	R:R:L572	R:R:L801	4.15	No	No	0	3	6
13	R:R:A573	R:R:V618	5.09	No	Yes	0	7	7
14	R:R:G576	R:R:Y615	2.9	No	Yes	0	6	8
15	R:R:F577	R:R:L612	7.31	No	No	0	6	4
16	R:R:F577	R:R:M616	4.98	No	No	0	6	6
17	R:R:L805	R:R:S579	3	No	No	0	2	4
18	R:R:L612	R:R:T580	2.95	No	No	0	4	8
19	R:R:T580	R:R:Y615	6.24	No	Yes	0	8	8
20	R:R:I583	R:R:L608	5.71	No	No	4	7	9
21	R:R:F808	R:R:I583	6.28	Yes	No	4	9	7
22	R:R:C812	R:R:I583	4.91	No	No	0	7	7
23	R:R:L584	R:R:L608	8.3	No	No	0	4	9
24	R:R:L584	R:R:T609	2.95	No	No	0	4	4
25	R:R:I586	R:R:I815	2.94	No	Yes	2	5	8
26	R:R:I586	R:R:L816	7.14	No	No	2	5	6
27	R:R:F587	R:R:V596	5.24	No	Yes	0	9	9
28	R:R:F587	R:R:F808	4.29	No	Yes	0	9	9
29	R:R:F605	R:R:W588	3.01	No	No	0	6	5
30	R:R:H590	R:R:R589	10.16	No	No	0	5	4
31	R:R:F591	R:R:V596	7.87	No	Yes	0	5	9
32	R:R:P594	R:R:T593	5.25	No	Yes	0	8	9
33	R:R:I595	R:R:T593	4.56	Yes	Yes	2	7	9
34	R:R:T593	R:R:V596	3.17	Yes	Yes	0	9	9
35	R:R:N822	R:R:T593	13.16	No	Yes	2	9	9
36	R:R:P594	R:R:P824	9.74	No	No	0	8	6
37	R:R:F827	R:R:P594	14.45	Yes	No	0	7	8
38	R:R:I595	R:R:K811	7.27	Yes	No	0	7	9
39	R:R:I595	R:R:I815	8.83	Yes	Yes	2	7	8
40	R:R:I595	R:R:N822	8.5	Yes	No	2	7	9
41	R:R:S598	R:R:Y756	5.09	No	Yes	1	9	9
42	R:R:F827	R:R:S598	5.28	Yes	No	1	7	9
43	R:R:A599	R:R:K811	3.21	No	No	0	9	9
44	R:R:G600	R:R:M603	3.49	No	No	0	9	8
45	R:R:G601	R:R:P602	4.06	No	No	0	8	6
46	R:R:C647	R:R:M603	6.48	No	No	0	7	8
47	R:R:C604	R:R:F808	5.59	No	Yes	0	9	9
48	R:R:C644	R:R:M607	3.24	No	Yes	0	7	8
49	R:R:C647	R:R:M607	3.24	No	Yes	0	7	8
50	R:R:I648	R:R:M607	4.37	No	Yes	0	7	8
51	R:R:F808	R:R:M607	3.73	Yes	Yes	0	9	8
52	R:R:F808	R:R:L608	14.61	Yes	No	4	9	9
53	R:R:C640	R:R:L610	3.17	Yes	No	0	7	8
54	R:R:I643	R:R:L610	4.28	Yes	No	0	7	8
55	R:R:C640	R:R:L611	3.17	Yes	No	0	7	9
56	R:R:M616	R:R:V613	3.04	No	No	0	6	6
57	R:R:L636	R:R:V613	2.98	No	No	0	6	6
58	R:R:A614	R:R:C640	3.61	No	Yes	0	6	7
59	R:R:L800	R:R:Y615	7.03	No	Yes	0	8	8
60	R:R:S804	R:R:Y615	3.82	No	Yes	0	8	8
61	R:R:C632	R:R:V617	3.42	No	No	5	6	6
62	R:R:L636	R:R:V617	8.94	No	No	5	6	6
63	R:R:P619	R:R:V618	3.53	No	Yes	0	6	7
64	R:R:F637	R:R:V618	3.93	No	Yes	0	8	7
65	R:R:V618	R:R:V797	3.21	Yes	No	0	7	9
66	R:R:T629	R:R:V620	3.17	No	No	0	6	6
67	R:R:R633	R:R:Y621	19.55	No	No	0	8	8
68	R:R:F637	R:R:Y621	9.28	No	No	0	8	8
69	R:R:L793	R:R:Y621	9.38	No	No	0	8	8
70	R:R:G623	R:R:P624	4.06	No	No	0	8	5
71	R:R:K626	R:R:S628	3.06	No	No	0	5	4
72	R:R:K626	R:R:T629	6.01	No	No	0	5	6
73	R:R:V627	S:S:A631	5.09	No	No	0	4	3
74	R:R:C632	R:R:L636	3.17	No	No	5	6	6
75	R:R:D792	R:R:R633	3.57	No	No	0	9	8
76	R:R:K689	R:R:P638	3.35	Yes	No	0	9	5
77	R:R:I643	R:R:L639	4.28	Yes	No	0	7	7
78	R:R:C640	R:R:L800	3.17	Yes	No	0	7	8
79	R:R:D735	R:R:F641	3.58	No	Yes	6	8	8
80	R:R:F641	R:R:Y769	11.35	Yes	Yes	6	8	8
81	R:R:F641	R:R:T796	5.19	Yes	No	0	8	8
82	R:R:F641	R:R:L800	6.09	Yes	No	0	8	8
83	R:R:I643	R:R:T642	3.04	Yes	No	0	7	8
84	R:R:K689	R:R:T642	18.02	Yes	No	0	9	8
85	R:R:I643	R:R:T686	3.04	Yes	No	0	7	7
86	R:R:C644	R:R:I803	3.27	No	No	0	7	8
87	R:R:D735	R:R:I645	8.4	No	No	0	8	7
88	R:R:I685	R:R:S646	6.19	No	No	0	5	9
89	R:R:C647	R:R:M682	3.24	No	No	0	7	7
90	R:R:I648	R:R:Y807	8.46	No	Yes	0	7	8
91	R:R:Q654	R:R:V650	4.3	No	No	0	8	8
92	R:R:I655	R:R:R651	3.76	No	No	0	9	9
93	R:R:E758	R:R:R651	6.98	No	No	0	9	9
94	R:R:R651	R:R:Y807	7.2	No	Yes	0	9	8
95	R:R:F653	R:R:W672	17.04	No	Yes	0	7	6
96	R:R:F653	R:R:F745	9.65	No	No	0	7	7
97	R:R:P678	R:R:Q654	11.05	Yes	No	0	8	8
98	R:R:I655	R:R:Y756	6.04	No	Yes	0	9	9
99	R:R:F745	R:R:V656	3.93	No	No	0	7	7
100	R:R:M748	R:R:V656	4.56	No	No	0	7	7
101	R:R:C657	R:R:Y669	4.03	No	No	0	6	7
102	R:R:F659	R:R:L752	4.87	Yes	Yes	1	9	8
103	R:R:F659	R:R:P753	7.22	Yes	Yes	1	9	9
104	R:R:F659	R:R:Y756	9.28	Yes	Yes	1	9	9
105	R:R:F659	R:R:Y834	6.19	Yes	Yes	1	9	6
106	R:R:K660	R:R:M748	4.32	No	No	0	6	7
107	R:R:E751	R:R:K660	6.75	No	No	0	7	6
108	R:R:M661	R:R:R664	4.96	No	No	0	7	7
109	R:R:F665	R:R:R664	6.41	No	No	0	5	7
110	R:R:A668	R:R:R667	4.15	No	No	0	5	5
111	R:R:R667	R:R:Y671	7.2	No	No	0	5	5
112	R:R:G677	R:R:W672	8.44	No	Yes	7	8	6
113	R:R:P678	R:R:W672	13.51	Yes	Yes	7	8	6
114	R:R:S681	R:R:W672	3.71	No	Yes	0	7	6
115	R:R:R674	R:R:Y675	13.38	No	No	0	7	6
116	R:R:G677	R:R:P678	4.06	No	Yes	7	8	8
117	R:R:F684	R:R:L688	4.87	No	No	0	3	6
118	R:R:I685	R:R:L738	5.71	No	No	0	5	9
119	R:R:K689	R:R:V693	4.55	Yes	No	0	9	7
120	R:R:K689	R:R:N731	4.2	Yes	No	0	9	7
121	R:R:M690	R:R:V693	3.04	No	No	0	4	7
122	R:R:I692	R:R:I695	2.94	No	Yes	0	6	4
123	R:R:F730	R:R:I692	3.77	No	No	0	4	6
124	R:R:M697	R:R:V694	3.04	No	No	0	7	4
125	R:R:M780	R:R:Y724	3.59	No	No	0	8	8
126	R:R:R725	R:R:S781	6.59	No	No	0	2	5
127	R:R:L728	R:R:T732	4.42	No	No	0	7	7
128	R:R:L729	R:R:T732	2.95	No	No	0	5	7
129	R:R:C777	R:R:L729	3.17	No	No	0	7	5
130	R:R:S773	R:R:T732	6.4	No	No	0	9	7
131	R:R:D735	R:R:Y769	12.64	No	Yes	6	8	8
132	R:R:F770	R:R:L736	12.18	No	No	0	6	6
133	R:R:M766	R:R:S739	6.13	No	No	0	9	8
134	R:R:G742	R:R:V741	3.68	No	Yes	0	9	4
135	R:R:F743	R:R:I762	3.77	Yes	No	0	8	9
136	R:R:F743	R:R:T763	3.89	Yes	No	0	8	9
137	R:R:F743	R:R:M766	7.46	Yes	No	0	8	9
138	R:R:K750	R:R:Y747	13.14	No	No	0	9	8
139	R:R:G749	R:R:L752	5.13	No	Yes	0	9	8
140	R:R:E751	R:R:Y834	10.1	No	Yes	0	7	6
141	R:R:L752	R:R:P753	3.28	Yes	Yes	1	8	9
142	R:R:L752	R:R:Y834	4.69	Yes	Yes	1	8	6
143	R:R:M830	R:R:P753	3.35	Yes	Yes	0	4	9
144	R:R:P753	R:R:Y834	15.3	Yes	Yes	1	9	6
145	R:R:N755	R:R:T754	5.85	No	No	0	8	7
146	R:R:F827	R:R:N755	10.87	Yes	No	0	7	8
147	R:R:M830	R:R:N755	5.61	Yes	No	0	4	8
148	R:R:F827	R:R:Y756	6.19	Yes	Yes	1	7	9
149	R:R:I831	R:R:Y756	4.84	No	Yes	0	7	9
150	R:R:A759	R:R:N757	3.13	No	No	0	9	9
151	R:R:E758	R:R:F761	4.66	No	Yes	0	9	5
152	R:R:F761	R:R:S765	5.28	Yes	No	0	5	9
153	R:R:F761	R:R:I803	3.77	Yes	No	0	5	8
154	R:R:F761	R:R:Y807	12.38	Yes	Yes	0	5	8
155	R:R:F768	R:R:S772	3.96	No	No	0	7	9
156	R:R:S773	R:R:Y769	3.82	No	Yes	0	9	8
157	R:R:N799	R:R:Y769	9.3	No	Yes	0	9	8
158	R:R:S772	R:R:V795	3.23	No	No	0	9	8
159	R:R:N799	R:R:S772	2.98	No	No	0	9	9
160	R:R:L776	R:R:M780	5.65	No	No	0	9	8
161	R:R:D792	R:R:L776	6.79	No	No	0	9	9
162	R:R:L776	R:R:V795	4.47	No	No	0	9	8
163	R:R:M780	R:R:V788	4.56	No	No	0	8	7
164	R:R:S784	R:R:Y783	6.36	No	No	0	6	8
165	R:R:V788	R:R:Y783	6.31	No	No	0	7	8
166	R:R:S784	R:R:V786	3.23	No	No	0	6	8
167	R:R:L787	R:R:V786	5.96	No	No	0	5	8
168	R:R:I790	R:R:L787	4.28	Yes	No	0	8	5
169	R:R:L793	R:R:T796	4.42	No	No	0	8	8
170	R:R:I803	R:R:N799	2.83	No	No	0	8	9
171	R:R:L805	R:R:S804	4.5	No	No	0	2	8
172	R:R:F808	R:R:Y807	11.35	Yes	Yes	0	9	8
173	R:R:K811	R:R:Y807	13.14	No	Yes	0	9	8
174	R:R:G809	R:R:P810	4.06	No	No	0	3	9
175	R:R:F817	R:R:Y813	9.28	No	No	0	5	8
176	R:R:Y813	R:R:Y818	2.98	No	Yes	0	8	6
177	R:R:I815	R:R:L816	2.85	Yes	No	2	8	6
178	R:R:I815	R:R:N822	7.08	Yes	No	2	8	9
179	R:R:R821	R:R:Y818	11.32	No	Yes	0	5	6
180	R:R:R821	R:R:Y826	11.32	No	No	0	5	5
181	R:R:P824	R:R:T823	3.5	No	No	0	6	7
182	R:R:M830	R:R:Y826	9.58	Yes	No	0	4	5
183	R:R:M836	R:R:Q832	4.08	No	No	0	7	8
184	R:R:T835	R:R:Y834	3.75	No	Yes	0	7	6
185	R:R:R837	R:R:Y834	7.2	No	Yes	0	7	6
186	S:S:E566	S:S:P567	3.14	No	No	0	7	3
187	S:S:P625	S:S:V569	3.53	No	No	0	7	7
188	S:S:L572	S:S:M795	4.24	Yes	Yes	0	8	7
189	S:S:G796	S:S:L572	3.42	No	Yes	0	7	8
190	S:S:L574	S:S:S577	3	No	No	0	3	4
191	S:S:L575	S:S:L799	5.54	No	No	0	3	8
192	S:S:L576	S:S:V621	2.98	No	Yes	0	6	7
193	S:S:L578	S:S:L803	4.15	No	No	0	4	6
194	S:S:A579	S:S:L803	3.15	No	No	0	6	6
195	S:S:G615	S:S:V583	5.52	No	No	0	4	7
196	S:S:L806	S:S:V583	5.96	Yes	No	0	8	7
197	S:S:A586	S:S:L611	3.15	No	Yes	0	7	9
198	S:S:L587	S:S:V591	2.98	No	No	3	4	4
199	S:S:C608	S:S:L587	3.17	No	No	3	6	4
200	S:S:L587	S:S:L611	5.54	No	Yes	3	4	9
201	S:S:C814	S:S:L589	6.35	No	No	0	8	5
202	S:S:L589	S:S:M818	4.24	No	No	0	5	6
203	S:S:F590	S:S:V599	9.18	Yes	No	0	9	9
204	S:S:F590	S:S:L611	6.09	Yes	Yes	3	9	9
205	S:S:F590	S:S:H810	3.39	Yes	Yes	3	9	9
206	S:S:C608	S:S:V591	3.42	No	No	3	6	4
207	S:S:H592	S:S:H593	9.55	No	No	0	3	5
208	S:S:H593	S:S:L817	9	No	No	0	5	8
209	S:S:D595	S:S:R594	10.72	No	No	0	5	5
210	S:S:P597	S:S:S596	5.34	No	No	0	8	9
211	S:S:L817	S:S:S596	3	No	No	0	8	9
212	S:S:N824	S:S:S596	2.98	No	No	0	9	9
213	S:S:P597	S:S:P826	3.9	No	No	0	8	6
214	S:S:F829	S:S:P597	4.33	Yes	No	0	6	8
215	S:S:L598	S:S:R813	4.86	Yes	Yes	0	7	9
216	S:S:L598	S:S:L816	4.15	Yes	No	0	7	8
217	S:S:L598	S:S:L817	9.69	Yes	No	0	7	8
218	S:S:F829	S:S:L598	7.31	Yes	Yes	0	6	7
219	S:S:A601	S:S:F829	4.16	No	Yes	0	9	6
220	S:S:Q654	S:S:S602	4.33	No	No	0	9	9
221	S:S:R813	S:S:S602	7.91	Yes	No	0	9	9
222	S:S:G603	S:S:Q654	3.29	No	No	0	9	9
223	S:S:G604	S:S:P605	4.06	No	No	0	8	6
224	S:S:L606	S:S:T650	8.84	No	No	0	8	8
225	S:S:L606	S:S:W682	9.11	No	No	0	8	5
226	S:S:C613	S:S:F609	4.19	No	No	0	8	6
227	S:S:F609	S:S:W682	5.01	No	No	0	6	5
228	S:S:H810	S:S:L611	15.43	Yes	Yes	3	9	9
229	S:S:L616	S:S:V612	2.98	No	No	0	5	4
230	S:S:C613	S:S:P643	3.77	No	Yes	0	8	6
231	S:S:C647	S:S:L614	7.94	No	No	0	7	9
232	S:S:L616	S:S:P643	3.28	No	Yes	0	5	6
233	S:S:P643	S:S:V617	5.3	Yes	No	0	6	5
234	S:S:L644	S:S:V617	2.98	Yes	No	0	8	5
235	S:S:V617	S:S:V802	3.21	No	No	0	5	8
236	S:S:C618	S:S:L799	3.17	No	No	0	8	8
237	S:S:C618	S:S:V802	5.12	No	No	0	8	8
238	S:S:S620	S:S:S640	3.26	No	No	0	6	7
239	S:S:M795	S:S:V621	7.61	Yes	Yes	0	7	7
240	S:S:L798	S:S:V621	4.47	No	Yes	0	8	7
241	S:S:L799	S:S:V621	10.43	No	Yes	0	8	7
242	S:S:L623	S:S:R632	3.64	No	No	0	5	6
243	S:S:F624	S:S:Q636	10.54	No	No	0	7	8
244	S:S:F624	S:S:Q794	9.37	No	No	0	7	8
245	S:S:F624	S:S:M795	6.22	No	Yes	0	7	7
246	S:S:M795	S:S:P625	3.35	Yes	No	0	7	7
247	S:S:P628	S:S:Q627	3.16	No	No	0	9	4
248	S:S:P630	S:S:S629	5.34	No	No	0	3	5
249	S:S:C633	S:S:Q636	4.58	No	No	0	9	8
250	S:S:L634	S:S:L700	4.15	No	No	0	5	7
251	S:S:H641	S:S:Q637	9.89	No	No	0	5	8
252	S:S:Q637	S:S:Y699	3.38	No	Yes	0	8	6
253	S:S:C696	S:S:P638	7.53	No	No	0	7	5
254	S:S:P638	S:S:Y699	8.34	No	Yes	10	5	6
255	S:S:L700	S:S:P638	4.93	No	No	10	7	5
256	S:S:L798	S:S:S640	4.5	No	No	0	8	7
257	S:S:A733	S:S:H641	4.39	No	No	0	6	5
258	S:S:H641	S:S:H734	8.36	No	No	0	5	7
259	S:S:L642	S:S:P643	3.28	No	Yes	0	7	6
260	S:S:L642	S:S:V693	4.47	No	No	0	7	4
261	S:S:L644	S:S:N737	4.12	Yes	Yes	0	8	7
262	S:S:C801	S:S:L644	3.17	No	Yes	0	9	8
263	S:S:G646	S:S:T645	3.64	No	No	0	6	7
264	S:S:E692	S:S:T645	14.11	No	No	0	9	7
265	S:S:N737	S:S:T645	7.31	Yes	No	0	7	7
266	S:S:G646	S:S:M689	3.49	No	No	0	6	7
267	S:S:L648	S:S:M768	2.83	No	Yes	0	7	9
268	S:S:S649	S:S:V685	4.85	No	No	0	9	8
269	S:S:A688	S:S:S649	3.42	No	No	0	4	9
270	S:S:L740	S:S:S649	3	No	No	0	9	9
271	S:S:F809	S:S:L651	6.09	Yes	No	0	8	7
272	S:S:F652	S:S:L740	6.09	No	No	0	8	9
273	S:S:F652	S:S:L743	3.65	No	No	0	8	4
274	S:S:L653	S:S:V684	5.96	Yes	No	0	7	6
275	S:S:F809	S:S:Q654	5.86	Yes	No	0	8	9
276	S:S:A655	S:S:C744	3.61	No	No	0	9	8
277	S:S:A655	S:S:T748	3.36	No	No	0	9	9
278	S:S:E657	S:S:E661	8.88	No	No	0	8	8
279	S:S:E657	S:S:R760	6.98	No	No	0	8	9
280	S:S:I658	S:S:R760	15.03	No	No	0	9	9
281	S:S:F659	S:S:L664	3.65	No	Yes	0	6	6
282	S:S:F659	S:S:G747	4.52	No	No	0	6	7
283	S:S:L672	S:S:V660	5.96	No	No	0	4	6
284	S:S:E661	S:S:S673	5.75	No	No	0	8	5
285	S:S:E663	S:S:S662	4.31	No	No	0	6	9
286	S:S:S662	S:S:V751	3.23	No	No	0	9	8
287	S:S:E663	S:S:L750	6.63	No	No	0	6	8
288	S:S:L664	S:S:P665	3.28	Yes	No	0	6	7
289	S:S:G674	S:S:S673	3.71	No	No	0	6	5
290	S:S:C675	S:S:W680	9.14	No	No	0	4	7
291	S:S:G678	S:S:R677	3	No	No	0	5	6
292	S:S:G678	S:S:P679	4.06	No	No	0	5	3
293	S:S:P679	S:S:W680	4.05	No	No	0	3	7
294	S:S:C696	S:S:E692	4.56	No	No	0	7	9
295	S:S:E692	S:S:T736	8.47	No	No	0	9	8
296	S:S:F703	S:S:W698	7.02	Yes	No	0	5	4
297	S:S:L732	S:S:W698	6.83	No	No	0	4	4
298	S:S:L700	S:S:Y699	9.38	No	Yes	10	7	6
299	S:S:F703	S:S:Y699	3.09	Yes	Yes	0	5	6
300	S:S:S729	S:S:Y699	7.63	No	Yes	0	6	6
301	S:S:F703	S:S:V728	3.93	Yes	No	0	5	3
302	S:S:F730	S:S:W727	8.02	No	No	0	7	3
303	S:S:F730	S:S:G731	3.01	No	No	0	7	4
304	S:S:F730	S:S:H734	7.92	No	No	0	7	7
305	S:S:H734	S:S:W775	16.93	No	Yes	0	7	9
306	S:S:N737	S:S:T736	2.92	Yes	No	0	7	8
307	S:S:N737	S:S:Y771	4.65	Yes	No	0	7	8
308	S:S:A741	S:S:M768	3.22	No	Yes	0	8	9
309	S:S:F742	S:S:L746	8.53	No	No	0	3	4
310	S:S:C744	S:S:L764	4.76	No	No	0	8	9
311	S:S:C744	S:S:M768	8.1	No	Yes	0	8	9
312	S:S:F745	S:S:F749	9.65	Yes	No	0	9	8
313	S:S:F745	S:S:T765	6.49	Yes	No	0	9	9
314	S:S:F745	S:S:M768	4.98	Yes	Yes	0	9	9
315	S:S:L764	S:S:T748	5.9	No	No	0	9	9
316	S:S:T748	S:S:T765	3.14	No	No	0	9	9
317	S:S:F749	S:S:L750	8.53	No	No	0	8	8
318	S:S:A761	S:S:V751	3.39	No	No	0	9	8
319	S:S:N759	S:S:S753	11.92	No	No	0	9	7
320	S:S:Q754	S:S:R757	7.01	No	No	0	8	9
321	S:S:R813	S:S:Y758	8.23	Yes	Yes	0	9	9
322	S:S:L816	S:S:Y758	3.52	No	Yes	0	8	9
323	S:S:F828	S:S:Y758	4.13	No	Yes	9	5	9
324	S:S:F829	S:S:Y758	11.35	Yes	Yes	9	6	9
325	S:S:G763	S:S:R762	3	No	Yes	0	5	9
326	S:S:F766	S:S:R762	12.83	No	Yes	0	9	9
327	S:S:P812	S:S:R762	2.88	No	Yes	0	9	9
328	S:S:F809	S:S:L764	4.87	Yes	No	0	8	9
329	S:S:A767	S:S:I805	3.25	No	No	0	9	7
330	S:S:F772	S:S:Y771	5.16	No	No	0	6	8
331	S:S:W775	S:S:Y771	15.43	Yes	No	0	9	8
332	S:S:T774	S:S:W775	4.85	No	Yes	0	9	9
333	S:S:L800	S:S:T774	2.95	No	No	0	6	9
334	S:S:F778	S:S:L782	8.53	Yes	No	0	9	8
335	S:S:A797	S:S:F778	6.93	No	Yes	0	8	9
336	S:S:P780	S:S:V779	3.53	No	No	0	9	6
337	S:S:L781	S:S:V785	2.98	No	No	11	7	7
338	S:S:L781	S:S:V793	2.98	No	No	11	7	8
339	S:S:L782	S:S:R790	3.64	No	No	0	8	7
340	S:S:L789	S:S:V785	2.98	No	No	0	5	7
341	S:S:V785	S:S:V793	4.81	No	No	11	7	8
342	S:S:R790	S:S:V787	5.23	No	No	0	7	7
343	S:S:P791	S:S:R790	2.88	No	No	0	6	7
344	S:S:H810	S:S:L806	3.86	Yes	Yes	0	9	8
345	S:S:F809	S:S:H810	14.71	Yes	Yes	0	8	9
346	S:S:F809	S:S:R813	8.55	Yes	Yes	0	8	9
347	S:S:L811	S:S:P812	4.93	No	No	0	4	9
348	S:S:R819	S:S:Y815	4.12	No	No	0	5	8
349	S:S:L816	S:S:Q820	5.32	No	No	0	8	6
350	S:S:L823	S:S:Q820	6.65	No	No	0	5	6
351	S:S:P826	S:S:T825	3.5	No	No	0	6	7
352	S:S:F828	S:S:T825	3.89	No	No	0	5	7
353	S:S:F828	S:S:F829	8.57	No	Yes	9	5	6
354	R:R:K689	R:R:L734	2.82	Yes	No	0	9	8
355	R:R:K760	R:R:L764	2.82	No	No	0	9	9
356	R:R:C657	R:R:F653	2.79	No	No	0	6	7
357	S:S:C814	S:S:F590	2.79	No	Yes	0	8	9
358	R:R:A668	R:R:F665	2.77	No	No	0	5	5
359	R:R:L688	R:R:L734	2.77	No	No	0	6	8
360	R:R:A802	R:R:F768	2.77	No	No	0	7	7
361	R:R:L794	R:R:L798	2.77	No	No	0	7	7
362	S:S:L571	S:S:L572	2.77	No	Yes	0	3	8
363	S:S:L576	S:S:L622	2.77	No	No	8	6	6
364	S:S:L580	S:S:L584	2.77	No	No	0	5	2
365	S:S:L580	S:S:L619	2.77	No	No	0	5	5
366	S:S:A607	S:S:F590	2.77	No	Yes	0	8	9
367	S:S:L614	S:S:L806	2.77	No	Yes	0	9	8
368	S:S:L623	S:S:L639	2.77	No	No	0	5	6
369	S:S:L644	S:S:L648	2.77	Yes	No	0	8	7
370	S:S:L653	S:S:L676	2.77	Yes	No	0	7	6
371	S:S:L686	S:S:L690	2.77	No	No	0	3	4
372	S:S:L695	S:S:L732	2.77	No	No	0	7	4
373	S:S:A702	S:S:F703	2.77	No	Yes	0	3	5
374	S:S:A741	S:S:F772	2.77	No	No	0	8	6
375	S:S:L623	S:S:Q636	2.66	No	No	0	5	8
376	R:R:H590	R:R:I586	2.65	No	No	0	5	5
377	R:R:F770	R:R:V774	2.62	No	No	0	6	6
378	S:S:F778	S:S:V793	2.62	Yes	No	0	9	8
379	R:R:F779	R:R:T778	2.59	No	No	0	7	8
380	S:S:F766	S:S:T765	2.59	No	No	0	9	9
381	S:S:A797	S:S:W775	2.59	No	Yes	0	8	9
382	S:S:V685	S:S:W682	2.45	No	No	0	8	5
383	R:R:F605	R:R:L584	2.44	No	No	0	6	4
384	S:S:F652	S:S:L653	2.44	No	Yes	0	8	7
385	S:S:F745	S:S:L769	2.44	Yes	No	0	9	8
386	S:S:F829	S:S:L830	2.44	Yes	No	0	6	8
387	S:S:N759	S:S:R762	2.41	No	Yes	0	9	9
388	R:R:M814	R:R:Y818	2.39	No	Yes	0	8	6
389	R:R:D839	R:R:R837	2.38	No	No	0	5	7
390	S:S:E663	S:S:F659	2.33	No	No	0	6	6
391	S:S:L664	S:S:W668	2.28	Yes	No	0	6	5
392	R:R:Q676	R:R:Y679	2.25	No	No	0	3	5
393	S:S:F742	S:S:F772	2.14	No	No	0	3	6
394	R:R:G600	R:R:G601	2.11	No	No	0	9	8
395	S:S:G603	S:S:G604	2.11	No	No	0	9	8
396	R:R:R674	R:R:Y671	2.06	No	No	0	7	5
397	R:R:F743	R:R:Y747	2.06	Yes	No	0	8	8
398	S:S:G626	S:S:P625	2.03	No	No	0	8	7
399	S:S:C613	S:S:G610	1.96	No	No	0	8	8
400	S:S:C647	S:S:G610	1.96	No	No	0	7	8
401	R:R:P624	R:R:P625	1.95	No	No	0	5	9
402	R:R:A649	R:R:G742	1.95	No	No	0	8	9
403	S:S:A770	S:S:G804	1.95	No	No	0	7	7
404	R:R:A564	R:R:P565	1.87	No	No	0	4	6
405	R:R:G785	R:R:S784	1.86	No	No	0	7	6
406	R:R:G623	R:R:V622	1.84	No	No	0	8	7
407	R:R:G677	R:R:V680	1.84	No	No	0	8	4
408	S:S:G588	S:S:V591	1.84	No	No	0	1	4
409	S:S:A579	S:S:C618	1.81	No	No	0	6	8
410	S:S:A767	S:S:A808	1.79	No	No	0	9	6
411	R:R:G696	R:R:I695	1.76	No	Yes	0	7	4
412	R:R:G576	R:R:L575	1.71	No	No	0	6	2
413	R:R:A746	R:R:S652	1.71	No	No	0	9	9
414	R:R:G806	R:R:L805	1.71	No	No	0	6	2
415	S:S:G615	S:S:L580	1.71	No	No	0	4	5
416	S:S:G581	S:S:L584	1.71	No	No	0	2	2
417	S:S:A631	S:S:S629	1.71	No	No	0	3	5
418	S:S:A669	S:S:V660	1.7	No	No	0	7	6
419	R:R:A825	R:R:T823	1.68	No	No	0	6	7
420	R:R:G833	R:R:Q832	1.64	No	No	0	4	8
421	S:S:C647	S:S:I805	1.64	No	No	0	7	7
422	S:S:C801	S:S:I805	1.64	No	No	0	9	7
423	R:R:S739	R:R:S765	1.63	No	No	0	8	9
424	R:R:S744	R:R:V741	1.62	No	Yes	0	4	4
425	R:R:V791	R:R:V795	1.6	No	No	0	7	8
426	R:R:T778	R:R:V774	1.59	No	No	0	8	6
427	R:R:A635	R:R:L631	1.58	No	No	0	5	5
428	R:R:P638	R:R:Q634	1.58	No	No	0	5	8
429	S:S:A568	S:S:L789	1.58	No	No	0	6	5
430	S:S:A792	S:S:L572	1.58	No	Yes	0	7	8
431	S:S:A681	S:S:L606	1.58	No	No	0	8	8
432	S:S:A635	S:S:L639	1.58	No	No	0	6	6
433	S:S:A681	S:S:L653	1.58	No	Yes	0	8	7
434	S:S:A656	S:S:L676	1.58	No	No	0	7	6
435	S:S:A669	S:S:L666	1.58	No	No	0	7	5
436	S:S:P755	S:S:Q754	1.58	No	No	0	9	8
437	S:S:A792	S:S:L789	1.58	No	No	0	7	5
438	S:S:P821	S:S:Q820	1.58	No	No	0	9	6
439	R:R:I695	R:R:V691	1.54	Yes	No	0	4	3
440	R:R:I695	R:R:V694	1.54	Yes	No	0	4	4
441	S:S:I658	S:S:V751	1.54	No	No	0	9	8
442	R:R:C630	R:R:Q634	1.53	No	No	0	9	8
443	R:R:M830	R:R:S829	1.53	Yes	No	0	4	5
444	R:R:I685	R:R:T642	1.52	No	No	0	5	8
445	R:R:M661	R:R:V656	1.52	No	No	0	7	7
446	R:R:M690	R:R:V694	1.52	No	No	0	4	4
447	R:R:M697	R:R:V693	1.52	No	No	0	7	7
448	R:R:M766	R:R:V740	1.52	No	No	0	9	2
449	R:R:I790	R:R:T789	1.52	Yes	No	0	8	7
450	R:R:L728	R:R:S727	1.5	No	No	0	7	6
451	S:S:G674	S:S:R677	1.5	No	No	0	6	6
452	R:R:L581	R:R:V585	1.49	No	No	0	3	1
453	R:R:L737	R:R:V741	1.49	No	Yes	0	4	4
454	S:S:L664	S:S:V660	1.49	Yes	No	0	6	6
455	S:S:L695	S:S:V691	1.49	No	No	0	7	5
456	S:S:D670	S:S:S667	1.47	No	No	0	4	6
457	R:R:F665	R:R:P666	1.44	No	No	0	5	7
458	S:S:F703	S:S:P704	1.44	Yes	No	0	5	7
459	R:R:I643	R:R:L606	1.43	Yes	No	0	7	6
460	S:S:E566	S:S:V569	1.43	No	No	0	7	7
461	S:S:E566	S:S:V788	1.43	No	No	0	7	7
462	S:S:Q786	S:S:V787	1.43	No	No	0	6	7
463	R:R:L631	R:R:M697	1.41	No	No	0	5	7
464	R:R:P678	R:R:Y679	1.39	Yes	No	0	8	5
465	R:R:P819	R:R:Y818	1.39	No	Yes	0	8	6
466	R:R:L581	R:R:L612	1.38	No	No	0	3	4
467	S:S:L573	S:S:L576	1.38	No	No	8	5	6
468	S:S:L573	S:S:L622	1.38	No	No	8	5	6
469	S:S:L582	S:S:L803	1.38	No	No	0	4	6
470	S:S:L582	S:S:L806	1.38	No	Yes	0	4	8
471	S:S:L683	S:S:L686	1.38	No	No	0	4	3
472	R:R:L752	R:R:N757	1.37	Yes	No	0	8	9
473	S:S:R632	S:S:S629	1.32	No	No	0	6	5
474	R:R:R597	R:R:V596	1.31	No	Yes	0	7	9
475	R:R:F745	R:R:V741	1.31	No	Yes	0	7	4
476	S:S:F778	S:S:V779	1.31	Yes	No	0	9	6
477	R:R:F768	R:R:T771	1.3	No	No	0	7	8
478	R:R:S670	R:R:Y671	1.27	No	No	0	4	5
479	R:R:L729	R:R:R725	1.21	No	No	0	5	2
480	R:R:D839	R:R:R838	1.19	No	No	0	5	4
481	S:S:D670	S:S:R671	1.19	No	No	0	4	4
482	R:R:F591	R:R:Q592	1.17	No	No	0	5	4

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:T593	6.535	4	2	9
2	R:R:I595	7.29	4	2	7
3	R:R:V596	4.3975	4	0	9
4	R:R:M607	3.645	4	0	8
5	R:R:Y615	4.9975	4	0	8
6	R:R:V618	3.94	4	0	7
7	R:R:C640	3.28	4	0	7
8	R:R:F641	6.5525	4	6	8
9	R:R:I643	3.214	5	0	7
10	R:R:F659	6.89	4	1	9
11	R:R:W672	10.675	4	7	6
12	R:R:P678	7.5025	4	7	8
13	R:R:K689	6.588	5	0	9
14	R:R:I695	1.945	4	0	4
15	R:R:V741	2.025	4	0	4
16	R:R:F743	4.295	4	0	8
17	R:R:L752	3.868	5	1	8
18	R:R:P753	7.2875	4	1	9
19	R:R:Y756	6.288	5	1	9
20	R:R:F761	6.5225	4	0	5
21	R:R:Y769	9.2775	4	6	8
22	R:R:I790	2.9225	4	0	8
23	R:R:Y807	10.506	5	0	8
24	R:R:F808	7.64167	6	4	9
25	R:R:I815	5.425	4	2	8
26	R:R:Y818	4.52	4	0	6
27	R:R:F827	9.1975	4	1	7
28	R:R:M830	5.0175	4	0	4
29	R:R:Y834	7.87167	6	1	6
30	S:S:L572	3.0025	4	0	8
31	S:S:F590	4.844	5	3	9
32	S:S:L598	6.5025	4	0	7
33	S:S:L611	7.5525	4	3	9
34	S:S:V621	6.3725	4	0	7
35	S:S:P643	3.9075	4	0	6
36	S:S:L644	3.26	4	0	8
37	S:S:L653	3.1875	4	0	7
38	S:S:L664	2.675	4	0	6
39	S:S:Y699	6.364	5	10	6
40	S:S:F703	3.65	5	0	5
41	S:S:N737	4.75	4	0	7
42	S:S:F745	5.89	4	0	9
43	S:S:Y758	6.8075	4	9	9
44	S:S:R762	5.28	4	0	9
45	S:S:M768	4.7825	4	0	9
46	S:S:W775	9.95	4	0	9
47	S:S:F778	4.8475	4	0	9
48	S:S:M795	5.355	4	0	7
49	S:S:L806	3.4925	4	0	8
50	S:S:F809	8.016	5	0	8
51	S:S:H810	9.3475	4	3	9
52	S:S:R813	7.3875	4	0	9
53	S:S:F829	6.36	6	9	6

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:I790	R:R:L787	17.0854	4.28	Yes	No	0	8	5
2	R:R:L787	R:R:V786	18.3395	5.96	No	No	0	5	8
3	R:R:S784	R:R:V786	19.5849	3.23	No	No	0	6	8
4	R:R:S784	R:R:Y783	22.0497	6.36	No	No	0	6	8
5	R:R:V788	R:R:Y783	23.2692	6.31	No	No	0	7	8
6	R:R:M780	R:R:V788	24.48	4.56	No	No	0	8	7
7	R:R:L776	R:R:M780	26.8757	5.65	No	No	0	9	8
8	R:R:L793	R:R:V569	11.4378	4.47	No	No	0	8	8
9	R:R:L800	R:R:Y615	22.0497	7.03	No	Yes	0	8	8
10	R:R:F641	R:R:L800	62.2962	6.09	Yes	No	0	8	8
11	R:R:F641	R:R:Y769	73.2368	11.35	Yes	Yes	6	8	8
12	R:R:N799	R:R:Y769	81.4876	9.3	No	Yes	0	9	8
13	R:R:N799	R:R:S772	34.733	2.98	No	No	0	9	9
14	R:R:S772	R:R:V795	30.4432	3.23	No	No	0	9	8
15	R:R:L776	R:R:V795	28.3935	4.47	No	No	0	9	8
16	R:R:L612	R:R:T580	11.9827	2.95	No	No	0	4	8
17	R:R:T580	R:R:Y615	13.2714	6.24	No	Yes	0	8	8
18	R:R:F808	R:R:M607	11.2216	3.73	Yes	Yes	0	9	8
19	R:R:C644	R:R:M607	12.1254	3.24	No	Yes	0	7	8
20	R:R:C644	R:R:I803	12.4281	3.27	No	No	0	7	8
21	R:R:I803	R:R:N799	100	2.83	No	No	0	8	9
22	R:R:F808	R:R:Y807	14.1838	11.35	Yes	Yes	0	9	8
23	R:R:F761	R:R:Y807	54.5859	12.38	Yes	Yes	0	5	8
24	R:R:F761	R:R:I803	89.9459	3.77	Yes	No	0	5	8
25	R:R:F827	R:R:Y756	19.2865	6.19	Yes	Yes	1	7	9
26	R:R:I655	R:R:Y756	82.3395	6.04	No	Yes	0	9	9
27	R:R:I655	R:R:R651	83.2822	3.76	No	No	0	9	9
28	R:R:E758	R:R:R651	38.0368	6.98	No	No	0	9	9
29	R:R:E758	R:R:F761	38.3005	4.66	No	Yes	0	9	5
30	R:R:R651	R:R:Y807	46.4995	7.2	No	Yes	0	9	8
31	R:R:C640	R:R:L800	44.7914	3.17	Yes	No	0	7	8
32	R:R:C640	R:R:L610	41.6043	3.17	Yes	No	0	7	8
33	R:R:I643	R:R:L610	40.5232	4.28	Yes	No	0	7	8
34	R:R:K689	R:R:T642	31.5632	18.02	Yes	No	0	9	8
35	R:R:I643	R:R:T642	36.1124	3.04	Yes	No	0	7	8
36	R:R:L793	R:R:T796	18.4043	4.42	No	No	0	8	8
37	R:R:F659	R:R:Y756	68.8562	9.28	Yes	Yes	1	9	9
38	R:R:F659	R:R:Y834	49.8854	6.19	Yes	Yes	1	9	6
39	R:R:E751	R:R:Y834	46.0757	10.1	No	Yes	0	7	6
40	R:R:E751	R:R:K660	44.7697	6.75	No	No	0	7	6
41	R:R:K660	R:R:M748	43.4551	4.32	No	No	0	6	7
42	R:R:M748	R:R:V656	42.1319	4.56	No	No	0	7	7
43	R:R:F745	R:R:V656	27.0054	3.93	No	No	0	7	7
44	R:R:F653	R:R:F745	18.3135	9.65	No	No	0	7	7
45	R:R:F653	R:R:W672	13.8508	17.04	No	Yes	0	7	6
46	R:R:F659	R:R:P753	12.4454	7.22	Yes	Yes	1	9	9
47	R:R:M661	R:R:V656	15.347	1.52	No	No	0	7	7
48	R:R:M661	R:R:R664	13.8508	4.96	No	No	0	7	7
49	R:R:F665	R:R:R664	12.3459	6.41	No	No	0	5	7
50	R:R:K689	R:R:V693	22.0497	4.55	Yes	No	0	9	7
51	R:R:I695	R:R:V694	13.12	1.54	Yes	No	0	4	4
52	R:R:M697	R:R:V693	11.7232	1.52	No	No	0	7	7
53	R:R:S773	R:R:Y769	10.6854	3.82	No	Yes	0	9	8
54	R:R:F761	R:R:S765	11.9092	5.28	Yes	No	0	5	9
55	R:R:S739	R:R:S765	10.6162	1.63	No	No	0	8	9
56	R:R:M830	R:R:P753	13.1935	3.35	Yes	Yes	0	4	9
57	R:R:F827	R:R:N755	15.6584	10.87	Yes	No	0	7	8
58	R:R:M830	R:R:N755	13.2714	5.61	Yes	No	0	4	8
59	R:R:R821	R:R:Y818	14.2659	11.32	No	Yes	0	5	6
60	R:R:R821	R:R:Y826	17.0941	11.32	No	No	0	5	5
61	R:R:M830	R:R:Y826	19.9135	9.58	Yes	No	0	4	5
62	R:R:F641	R:R:T796	19.4249	5.19	Yes	No	0	8	8
63	S:S:F624	S:S:Q636	10.3092	10.54	No	No	0	7	8
64	S:S:F624	S:S:M795	12.2724	6.22	No	Yes	0	7	7
65	S:S:M795	S:S:V621	20.0303	7.61	Yes	Yes	0	7	7
66	S:S:L799	S:S:V621	24.813	10.43	No	Yes	0	8	7
67	S:S:C618	S:S:L799	26.1189	3.17	No	No	0	8	8
68	S:S:A579	S:S:C618	12.147	1.81	No	No	0	6	8
69	S:S:A579	S:S:L803	11.7622	3.15	No	No	0	6	6
70	S:S:L582	S:S:L803	11.7535	1.38	No	No	0	4	6
71	S:S:L582	S:S:L806	12.2465	1.38	No	Yes	0	4	8
72	S:S:H810	S:S:L806	23.0357	3.86	Yes	Yes	0	9	8
73	S:S:F809	S:S:H810	26.6897	14.71	Yes	Yes	0	8	9
74	S:S:F809	S:S:R813	32.4108	8.55	Yes	Yes	0	8	9
75	S:S:L598	S:S:R813	16.6184	4.86	Yes	Yes	0	7	9
76	S:S:R813	S:S:Y758	14.4043	8.23	Yes	Yes	0	9	9
77	S:S:C618	S:S:V802	19.0357	5.12	No	No	0	8	8
78	S:S:V617	S:S:V802	19.3686	3.21	No	No	0	5	8
79	S:S:P643	S:S:V617	16.4584	5.3	Yes	No	0	6	5
80	S:S:C613	S:S:P643	14.1449	3.77	No	Yes	0	8	6
81	S:S:C613	S:S:F609	16.3892	4.19	No	No	0	8	6
82	S:S:F609	S:S:W682	15.4941	5.01	No	No	0	6	5
83	S:S:L644	S:S:V617	27.7405	2.98	Yes	No	0	8	5
84	S:S:L614	S:S:L806	12.8908	2.77	No	Yes	0	9	8
85	S:S:C647	S:S:L614	12.7092	7.94	No	No	0	7	9
86	S:S:L644	S:S:N737	33.76	4.12	Yes	Yes	0	8	7
87	S:S:N737	S:S:T645	14.9881	7.31	Yes	No	0	7	7
88	S:S:E692	S:S:T645	12.4065	14.11	No	No	0	9	7
89	S:S:C696	S:S:E692	22.867	4.56	No	No	0	7	9
90	S:S:C696	S:S:P638	21.1243	7.53	No	No	0	7	5
91	S:S:N737	S:S:T736	13.1286	2.92	Yes	No	0	7	8
92	S:S:E692	S:S:T736	12.2681	8.47	No	No	0	9	8
93	S:S:A797	S:S:F778	11.9611	6.93	No	Yes	0	8	9
94	S:S:A797	S:S:W775	12.5535	2.59	No	Yes	0	8	9
95	S:S:H734	S:S:W775	12.3503	16.93	No	Yes	0	7	9
96	S:S:P638	S:S:Y699	16.307	8.34	No	Yes	10	5	6
97	S:S:L644	S:S:L648	29.28	2.77	Yes	No	0	8	7
98	S:S:L648	S:S:M768	29.133	2.83	No	Yes	0	7	9
99	S:S:C744	S:S:M768	28.947	8.1	No	Yes	0	8	9
100	S:S:C744	S:S:L764	27.4205	4.76	No	No	0	8	9
101	S:S:L764	S:S:T748	11.1914	5.9	No	No	0	9	9
102	S:S:F809	S:S:L764	36.9384	4.87	Yes	No	0	8	9
103	S:S:F745	S:S:M768	31.1654	4.98	Yes	Yes	0	9	9
104	S:S:F745	S:S:T765	14.3351	6.49	Yes	No	0	9	9
105	S:S:T748	S:S:T765	10.7373	3.14	No	No	0	9	9
106	S:S:F745	S:S:F749	32.0389	9.65	Yes	No	0	9	8
107	S:S:F749	S:S:L750	30.9146	8.53	No	No	0	8	8
108	S:S:E663	S:S:L750	29.7816	6.63	No	No	0	6	8
109	S:S:E663	S:S:S662	17.9762	4.31	No	No	0	6	9
110	S:S:S662	S:S:V751	16.7481	3.23	No	No	0	9	8
111	S:S:I658	S:S:V751	14.2659	1.54	No	No	0	9	8
112	S:S:I658	S:S:R760	13.0119	15.03	No	No	0	9	9
113	S:S:E657	S:S:R760	11.7492	6.98	No	No	0	8	9
114	S:S:E657	S:S:E661	10.4778	8.88	No	No	0	8	8
115	S:S:E663	S:S:F659	11.7492	2.33	No	No	0	6	6
116	S:S:F703	S:S:Y699	18.0541	3.09	Yes	Yes	0	5	6
117	S:S:A741	S:S:M768	16.2205	3.22	No	Yes	0	8	9
118	S:S:F772	S:S:Y771	15.9697	5.16	No	No	0	6	8
119	S:S:W775	S:S:Y771	20.3892	15.43	Yes	No	0	9	8
120	S:S:A741	S:S:F772	15.7232	2.77	No	No	0	8	6

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 9O38_nogp

PDB Summary
PDB	9O38_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	2.83
Number of Linked Nodes	457
Number of Links	482
Number of Hubs	53
Number of Links mediated by Hubs	195
Number of Communities	11
Number of Nodes involved in Communities	43
Number of Links involved in Communities	49

Path Summary
Number Of Nodes in MetaPath	121
Number Of Links MetaPath	120
Number of Shortest Paths	68490
Length Of Smallest Path	3
Average Path Length	14.8097
Length of Longest Path	36
Minimum Path Strength	1.33
Average Path Strength	5.75929
Maximum Path Strength	16.18
Minimum Path Correlation	0.7
Average Path Correlation	0.971014
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	5.26316
Average % Of Corr. Nodes	70.8268
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	34.0504
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• binding • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • D1 dopamine receptor binding • protein binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • molecular function regulator activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • enzyme regulator activity • cyclase regulator activity • enzyme activator activity • cyclase activator activity • molecular function activator activity • adenylate cyclase regulator activity • adenylate cyclase activator activity • cation binding • metal ion binding • taste receptor activity • molecular transducer activity • transmembrane signaling receptor activity • signaling receptor activity • G protein-coupled receptor activity • developmental process • multicellular organismal process • epithelium development • ectodermal placode morphogenesis • epidermis development • molting cycle process • hair cycle • animal organ development • hair follicle placode formation • tissue development • ectodermal placode formation • anatomical structure morphogenesis • skin development • skin epidermis development • hair follicle development
Gene Ontology	Biological Process	• developmental process • multicellular organismal process • epithelium development • ectodermal placode morphogenesis • epidermis development • molting cycle process • hair cycle • animal organ development • hair follicle placode formation • tissue development • ectodermal placode formation • anatomical structure morphogenesis • skin development • skin epidermis development • hair follicle development • molting cycle • anatomical structure development • anatomical structure formation involved in morphogenesis • ectodermal placode development • hair cycle process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of smell • cellular response to stimulus • cellular response to nitrogen compound • response to stimulus • response to endogenous stimulus • response to peptide hormone • cellular response to peptide hormone stimulus • response to oxygen-containing compound • response to nitrogen compound • response to glucagon • cellular response to oxygen-containing compound • cellular response to glucagon stimulus • cellular response to endogenous stimulus • cellular response to chemical stimulus • response to hormone • response to chemical • cellular process • cellular response to hormone stimulus • multicellular organism development • skeletal system development • bone development • system development • regulation of body fluid levels • wound healing • homotypic cell-cell adhesion • cell activation • hemostasis • biological regulation • platelet aggregation • blood coagulation • cell adhesion • cell-cell adhesion • response to stress • coagulation • regulation of biological quality • response to wounding • platelet activation • response to fluid shear stress • vascular endothelial cell response to laminar fluid shear stress • response to laminar fluid shear stress • cellular response to stress • cellular response to laminar fluid shear stress • vascular endothelial cell response to fluid shear stress • cellular response to fluid shear stress • cognition • developmental growth • growth • response to ketone • response to prostaglandin • response to lipid • response to alcohol • cellular response to prostaglandin stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • cellular response to lipid • response to prostaglandin E • cellular response to ketone • regulation of biological process • regulation of cellular process • signaling • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cell communication • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • signal transduction • homeostatic process • positive regulation of biological process • adaptive thermogenesis • positive regulation of metabolic process • multicellular organismal-level homeostasis • regulation of cold-induced thermogenesis • cold-induced thermogenesis • temperature homeostasis • positive regulation of cold-induced thermogenesis • positive regulation of multicellular organismal process • metabolic process • regulation of multicellular organismal process • regulation of metabolic process • positive regulation of cellular process • regulation of localization • establishment of protein localization • nitrogen compound transport • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • transport • hormone secretion • protein localization to extracellular region • localization • peptide secretion • regulation of secretion by cell • secretion by cell • amide transport • signal release • intracellular protein localization • regulation of peptide hormone secretion • regulation of signaling • regulation of transport • secretion • regulation of hormone levels • regulation of peptide transport • regulation of establishment of protein localization • establishment of protein localization to extracellular region • export from cell • cell-cell signaling • regulation of protein transport • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • peptide transport • protein transport • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • hormone transport • regulation of cell communication • insulin secretion • adenylate cyclase-activating adrenergic receptor signaling pathway • adrenergic receptor signaling pathway • cellular localization • establishment of localization in cell • intracellular transport • regulation of defense response • regulation of response to external stimulus • negative regulation of inflammatory response • negative regulation of biological process • inflammatory response to antigenic stimulus • regulation of response to stress • regulation of immune system process • negative regulation of inflammatory response to antigenic stimulus • defense response • immune response • negative regulation of response to stimulus • negative regulation of immune response • regulation of inflammatory response to antigenic stimulus • response to external stimulus • regulation of inflammatory response • regulation of response to stimulus • negative regulation of immune system process • immune system process • negative regulation of response to external stimulus • negative regulation of defense response • regulation of immune response • inflammatory response • positive regulation of adenylate cyclase activity • positive regulation of molecular function • regulation of molecular function • positive regulation of cyclase activity • activation of adenylate cyclase activity • regulation of adenylate cyclase activity • regulation of catalytic activity • positive regulation of catalytic activity • positive regulation of lyase activity • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • cellular response to monoamine stimulus • renal system process • chemical homeostasis • multicellular organismal-level water homeostasis • multicellular organismal-level chemical homeostasis • renal water homeostasis • sensory perception of sweet taste • sensory perception of taste • sensory perception of umami taste • detection of chemical stimulus involved in sensory perception of sweet taste • detection of chemical stimulus involved in sensory perception of taste • detection of stimulus • detection of chemical stimulus • detection of stimulus involved in sensory perception • detection of chemical stimulus involved in sensory perception • cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex
Gene Ontology	Cellular Component	• cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • membrane-bounded organelle • extracellular vesicle • extracellular organelle • extracellular region • organelle • extracellular space • vesicle • extracellular membrane-bounded organelle • intracellular anatomical structure • cytoplasm • cytosol • Golgi apparatus subcompartment • Golgi apparatus • organelle subcompartment • trans-Golgi network membrane • intracellular membrane-bounded organelle • endomembrane system • intracellular organelle • trans-Golgi network • organelle membrane • taste receptor complex • sweet taste receptor complex • receptor complex • protein binding • binding • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular process • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • signal transduction • cell communication • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • response to oxygen-containing compound • cellular response to oxygen-containing compound • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to chemical stimulus • cellular response to alcohol • response to hormone • response to chemical • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection • photoreceptor cell cilium • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome • synapse • cell junction • G-protein beta-subunit binding • fibroblast proliferation • taste receptor activity • molecular transducer activity • transmembrane signaling receptor activity • signaling receptor activity • G protein-coupled receptor activity • sweet taste receptor activity • sensory perception of sweet taste • regulation of cytokinesis • positive regulation of cell division • regulation of cell cycle process • positive regulation of biological process • cytokinesis • positive regulation of cell cycle • regulation of cell division • positive regulation of cytokinesis • positive regulation of cell cycle process • cell division • cell cycle • regulation of cell cycle • positive regulation of cellular process • cell cycle process • detection of chemical stimulus involved in sensory perception of sweet taste • detection of chemical stimulus involved in sensory perception of taste • detection of stimulus • detection of chemical stimulus • detection of stimulus involved in sensory perception • detection of chemical stimulus involved in sensory perception
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q8TE23
Sequence	>9O38_nogp_Chain_R L P C L V L E W H E A P T I A V A L L A A L G F L S T L A I L V I F W R H F Q T P I V R S A G G P M C F L M L T L L V A Y M V V P V Y V G P P K V S T C L C R Q A L F L C F T I C I S I A V R S F Q I V C A F K M A S R F P R A Y S Y W V R Y Q G P Y V S M A F I T V L K M V I V V I G M L A Y R N S L L F N T S L D L L L S V V G F S F A Y M G K E L P T N Y N E A K F I T S M T F Y F T S S V S L C T F M S A Y S G V L T I V D L L V T V L N L L A I S L G Y F G P K C Y M I L F Y P E R N T P A Y F N S M I Q G Y T M R R D Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	S
Protein	Receptor
UniProt	Q7RTX0
Sequence	>9O38_nogp_Chain_S E P A V L L L L L L L S L A L G L V L A A L G L F V H H R D S P L V Q A S G G P L A C F G L V C L G L V C L S V L L F P G Q P S P A R C L A Q Q P L S H L P L T G C L S T L F L Q A A E I F V E S E L P L S W A D R L S G C L R G P W A W L V V L L A M L V E V A L C T W Y L V A F P W V S F G L A H A T N A T L A F L C F L G T F L V R S Q P G Y N R A R G L T F A M L A Y F I T W V S F V P L L A N V Q V V L R P A V Q M G A L L L C V L G I L A A F H L P R C Y L L M R Q P G L N T P E F F L R Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	9NOX	C	Sensory	Taste1	TAS1R2	Homo sapiens	-	-	chim(Gs-CtGt3)/β1/γ2	3	2025-04-09	doi.org/10.1016/j.cell.2025.04.021
	9NOX (No Gprot)	C	Sensory	Taste1	TAS1R2	Homo sapiens	-	-		3	2025-04-09	doi.org/10.1016/j.cell.2025.04.021
	9NOY	C	Sensory	Taste1	TAS1R2	Homo sapiens	-	-	-	3.7	2025-04-09	doi.org/10.1016/j.cell.2025.04.021
	9NOR	C	Sensory	Taste1	TAS1R2; TAS1R3	Homo sapiens	-	-	-	3.4	2025-04-09	doi.org/10.1016/j.cell.2025.04.021
	9NOS	C	Sensory	Taste1	TAS1R2; TAS1R3	Homo sapiens	-	-	-	3.5	2025-04-09	doi.org/10.1016/j.cell.2025.04.021
	9NOT	C	Sensory	Taste1	TAS1R2; TAS1R3	Homo sapiens	-	-	-	3.8	2025-04-09	doi.org/10.1016/j.cell.2025.04.021
	9O38	C	Sensory	Taste1	TAS1R2; TAS1R3	Homo sapiens	-	-	chim(Gs-CtGt3)/β1/γ2	3	2025-04-09	doi.org/10.1016/j.cell.2025.04.021
	9O38 (No Gprot)	C	Sensory	Taste1	TAS1R2; TAS1R3	Homo sapiens	-	-		3	2025-04-09	doi.org/10.1016/j.cell.2025.04.021
	9OQ0	C	Sensory	Taste1	TAS1R2; TAS1R3	Homo sapiens; mus musculus	-	-	-	3.67	2025-08-27	To be published
	9UT8	C	Sensory	Taste1	TAS1R2; TAS1R3	Homo sapiens	-	-	-	3.41	2025-07-16	doi.org/10.1038/s41586-025-09302-6
	9UTA	C	Sensory	Taste1	TAS1R2; TAS1R3	Homo sapiens	-	-	-	3.77	2025-07-16	doi.org/10.1038/s41586-025-09302-6
	9UTB	C	Sensory	Taste1	TAS1R2; TAS1R3	Homo sapiens	Sucralose	-	-	3.59	2025-07-16	doi.org/10.1038/s41586-025-09302-6

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