Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index Hub Avg Int. Strength Num Of Links Community ConSurf
1S:S:L40 6.26416
2S:S:F41 6.4425408
3S:S:F65 4.534334
4S:S:N68 4.125484
5S:S:W72 8.52333685
6S:S:M76 4.91254308
7S:S:K77 6.2475465
8S:S:E82 5.024568
9S:S:Y97 8.266508
10S:S:F100 10.375404
11S:S:K111 4.62405
12S:S:F116 6.214505
13S:S:L117 6.75414
14S:S:D124 4.185401
15S:S:V141 5.44417
16S:S:P144 8.5625415
17S:S:H145 8.096585
18S:S:L149 4.696513
19S:S:T153 5.32616
20S:S:F156 5.838514
21S:S:F157 5.85143717
22S:S:F159 7.375415
23S:S:F160 12.6575415
24S:S:M162 3.62143716
25S:S:Q164 5.56833617
26S:S:Y167 8.4875487
27S:S:M171 4.6754357
28S:S:F183 6.37833618
29S:S:F184 9.1375406
30S:S:L200 4.565447
31S:S:E203 5.67445
32S:S:F204 7.71333648
33S:S:W206 10.618549
34S:S:W208 7.07609
35S:S:S214 5.21254127
36S:S:D216 6.52754126
37S:S:Y218 6.6356128
38S:S:R220 3.682505
39S:S:Q221 4.79254354
40S:S:L273 4.8245175
41S:S:F274 8.2156127
42S:S:F284 8.174174
43S:S:Y286 8.2125376
44S:S:W297 6.375408
45S:S:W303 7.606676177
46S:S:L304 4.315406
47S:S:V309 4.24254174
48S:S:T320 3.924548
49S:S:F324 5.812546
50S:S:L331 5.6675466
51S:S:F334 6.788567
52S:S:Y337 10.79467
53S:S:V338 3.545406
54S:S:C370 5.3954288
55S:S:H387 7.5775485
56S:S:Q389 6.90833684
57S:S:Y394 9.2775468
58S:S:Y398 9.89468
59S:S:S399 4.864228
60S:S:L404 6.554297
61S:S:C415 4.55508
62S:S:K422 5.4825413
63S:S:Q425 5.2775417
64S:S:M430 5.2025406
65S:S:L433 4.538336226
66S:S:F435 10.184229
67S:S:F444 6.294229
68S:S:N449 6.312517
69S:S:Y454 4.79333648
70S:S:D455 11.0354237
71S:S:L456 5.42447
72S:S:W459 6.968506
73S:S:W461 8.4425402
74S:S:V471 4.9275408
75S:S:R473 9.97254233
76S:S:F474 4.57286746
77S:S:W487 7.772548
78S:S:H488 5.716504
79S:S:P495 6.0525407
80S:S:Q507 7.2565187
81S:S:C517 4.44754369
82S:S:C518 4.33754369
83S:S:C538 3.455409
84S:S:C541 4.8375499
85S:S:W546 10.8625497
86S:S:S547 3.9498
87S:S:P548 6.82498
88S:S:C554 7.105499
89S:S:F561 5.86754196
90S:S:L587 3.5375404
91S:S:F590 4.8285409
92S:S:P597 4.97754148
93S:S:L598 6.5825407
94S:S:L611 7.6154409
95S:S:C618 3.015408
96S:S:F624 7.29407
97S:S:Q636 5.974418
98S:S:Q637 6.92254118
99S:S:P638 5.994115
100S:S:P643 4.32406
101S:S:E663 8.12754426
102S:S:L664 3.3525406
103S:S:Y699 5.953336116
104S:S:F703 7.6325115
105S:S:W711 5.5425403
106S:S:V720 6.1754196
107S:S:N737 5.1175407
108S:S:F745 5.3525409
109S:S:F749 5.645408
110S:S:L750 4.33254428
111S:S:Y758 6.80254149
112S:S:Y771 5.1475408
113S:S:W775 6.388509
114S:S:F778 4.722509
115S:S:V779 2.825406
116S:S:R790 4.6975407
117S:S:M795 5.296507
118S:S:F809 7.802508
119S:S:H810 9.314409
120S:S:R813 7.5625409
121S:S:Q820 1.685406
122S:S:F829 6.5325146
123R:R:Y33 3.8854455
124R:R:L38 4.64333617
125R:R:F39 5.634538
126R:R:L41 5.838535
127R:R:H42 5.265437
128R:R:M45 3.7025401
129R:R:F53 5.37402
130R:R:Y62 8.8675401
131R:R:V64 3.795404
132R:R:L71 4.19535
133R:R:M72 6.0975435
134R:R:M75 4.40833638
135R:R:F77 5.108538
136R:R:I82 6.0775409
137R:R:L88 4.3875408
138R:R:Y96 7.885638
139R:R:E97 7.8654255
140R:R:I98 6.16437
141R:R:Q109 5.9775414
142R:R:P110 5.355415
143R:R:Y113 7.75254253
144R:R:F114 5.2725416
145R:R:L115 4.948515
146R:R:L122 3.874344
147R:R:P123 5.26254343
148R:R:Y128 9.206504
149R:R:Y131 9.0854344
150R:R:P141 5.318516
151R:R:V147 5.195418
152R:R:V150 4.58517
153R:R:F153 5.37614
154R:R:L154 5.1875416
155R:R:F157 10.975417
156R:R:L158 3.864314
157R:R:Q161 5.694518
158R:R:T163 4.9275418
159R:R:Y164 5.74537
160R:R:L171 4.865417
161R:R:R172 10.068518
162R:R:F177 5.73833615
163R:R:L180 4.576518
164R:R:L181 7.42254266
165R:R:R182 7.264519
166R:R:P185 4.25254158
167R:R:H189 7.6854154
168R:R:E192 6.3745153
169R:R:F201 9.26558
170R:R:W203 7.472559
171R:R:W205 7.884297209
172R:R:I206 4.8275458
173R:R:I207 7.192528
174R:R:V208 4.93405
175R:R:Y215 6.208507
176R:R:R217 4.7775406
177R:R:R230 3.9125404
178R:R:I232 4.4325457
179R:R:C233 4.24754209
180R:R:E238 6.014525
181R:R:L264 6.025427
182R:R:V271 6.2725458
183R:R:V272 5.675426
184R:R:F275 6.09833608
185R:R:S276 5.6225424
186R:R:L281 5.85424
187R:R:F284 4.13833624
188R:R:F285 5.21333624
189R:R:E287 6.985425
190R:R:Q291 6.7825424
191R:R:F293 5.6825403
192R:R:V297 4.2175458
193R:R:W298 6.66429728
194R:R:I299 4.51407
195R:R:W304 7.17627
196R:R:D307 7.05405
197R:R:L316 5.2025424
198R:R:L319 4.44526
199R:R:F322 7.04571727
200R:R:I325 4.07407
201R:R:V330 7.7725434
202R:R:I332 4.545436
203R:R:F335 6.78438
204R:R:Q361 6.855252
205R:R:F373 5.995405
206R:R:R383 6.625425
207R:R:V385 5.492536
208R:R:Y386 6.495637
209R:R:V388 4.4375438
210R:R:Y389 6.26167638
211R:R:V392 3.9175409
212R:R:Y393 8.512538
213R:R:Y416 6.734324
214R:R:W418 9.2585323
215R:R:L421 5.5854316
216R:R:E423 6.2775405
217R:R:F429 8.965639
218R:R:L431 6.018537
219R:R:L432 4.03434
220R:R:Q435 5.07754243
221R:R:F437 4.374244
222R:R:Q452 4.0725458
223R:R:P461 4.778522
224R:R:F462 6.825424
225R:R:Y468 6.293336155
226R:R:P470 6.31754153
227R:R:R473 7.14754154
228R:R:I481 6.11457
229R:R:W483 7.06858
230R:R:H484 5.24404
231R:R:P491 6.59459
232R:R:K504 5.324485
233R:R:K505 9.655408
234R:R:I510 5.8625405
235R:R:F525 3.584107
236R:R:N527 13.174108
237R:R:C538 5.364109
238R:R:E542 8.91254106
239R:R:R554 6.495278
240R:R:T593 4.3275409
241R:R:I595 5.1975407
242R:R:M607 5.18578
243R:R:Y615 6.7025408
244R:R:V618 3.515407
245R:R:Y621 11.6275408
246R:R:F637 5.0725408
247R:R:F641 6.7745138
248R:R:I643 4.8407
249R:R:I648 4.975477
250R:R:R651 6.042579
251R:R:F653 5.35254167
252R:R:F665 4.035405
253R:R:W672 6.50254166
254R:R:P678 6.014168
255R:R:Y679 6.5375405
256R:R:K689 6.53409
257R:R:D712 5.3275404
258R:R:P713 3.77254274
259R:R:N721 6.4685516
260R:R:L736 6.474136
261R:R:S739 4.44254138
262R:R:N755 5.645478
263R:R:E758 8.582579
264R:R:I762 4.402579
265R:R:Y769 7.0825138
266R:R:M780 4.19408
267R:R:Y807 8.41678
268R:R:F808 6.395479
269R:R:I815 4.595408
270H:H:?901 13.41867100
271H:H:?902 17.7525400
272H:H:?904 11.15437240
273H:H:?905 13.854500
274H:H:?906 16.6354210
275H:H:?907 17.4554330
   

Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index Node1 Node2 Recurrence Int. Strength Hub1? Hub2? Community ConSurf1 ConSurf2
1S:S:E82 S:S:M78 55.07324.06YesNo687
2S:S:M78 S:S:Y337 55.289414.37NoYes677
3S:S:K77 S:S:Y337 55.46183.58YesYes657
4S:S:K77 S:S:Y97 56.497711.94YesYes058
5S:S:L99 S:S:Y97 28.6038.21NoYes078
6S:S:L29 S:S:L99 28.643612.46NoNo057
7S:S:L29 S:S:R369 28.68693.64NoNo051
8S:S:Q389 S:S:S392 14.57382.89YesNo047
9S:S:S392 S:S:T186 14.95513.2NoNo079
10S:S:A396 S:S:T186 15.03263.36NoNo099
11S:S:A396 S:S:V165 15.11975.09NoNo097
12S:S:S399 S:S:V165 15.23073.23YesNo087
13S:S:M430 S:S:P163 19.54223.35YesNo067
14S:S:G96 S:S:Y97 28.49412.9NoYes098
15S:S:G96 S:S:V36 28.53463.68NoNo095
16S:S:D98 S:S:V36 28.57792.92NoNo055
17S:S:M162 S:S:P163 23.04123.35YesNo067
18S:S:M162 S:S:V141 12.12783.04YesYes167
19S:S:F116 S:S:V141 50.84783.93YesYes057
20S:S:F157 S:S:M162 11.24464.98YesYes176
21S:S:F156 S:S:F157 31.72975.36YesYes147
22R:R:F153 S:S:F156 23.47786.43YesYes144
23R:R:F153 R:R:L115 18.23693.65YesYes145
24R:R:L115 R:R:L154 20.33964.15YesYes156
25R:R:L154 R:R:L159 18.72538.3YesNo066
26R:R:L159 R:R:P160 18.63173.28NoNo068
27R:R:L421 R:R:P160 16.95958.21YesNo068
28S:S:F100 S:S:F116 53.64648.57YesYes045
29S:S:D98 S:S:F100 28.62413.58NoYes054
30S:S:F100 S:S:R369 29.009519.24YesNo041
31H:H:?905 S:S:E82 54.84434.76YesYes008
32S:S:F160 S:S:L117 10.685715.83YesYes154
33S:S:F159 S:S:F160 16.710311.79YesYes155
34S:S:Q164 S:S:V141 55.52084.3YesYes177
35S:S:F157 S:S:Q164 44.43024.68YesYes177
36S:S:F183 S:S:Q164 10010.54YesYes187
37S:S:F183 S:S:R185 99.94333.21YesNo189
38S:S:N449 S:S:R185 99.96339.64YesNo179
39S:S:N449 S:S:S175 49.93628.94YesNo179
40S:S:E172 S:S:S175 49.92194.31NoNo059
41S:S:E172 S:S:R191 99.74716.28NoNo053
42S:S:I225 S:S:R191 99.66727.52NoNo033
43S:S:I225 S:S:L194 99.58745.71NoNo036
44S:S:F274 S:S:L194 94.68810.96YesNo076
45S:S:N449 S:S:S189 49.93622.98YesNo078
46S:S:E172 S:S:S189 49.90482.87NoNo058
47S:S:F274 S:S:Q193 84.03064.68YesNo079
48S:S:Q193 S:S:Y454 83.94763.38NoYes098
49S:S:E301 S:S:Y454 82.54553.37NoYes088
50S:S:F274 S:S:Y218 10.675716.5YesYes1278
51H:H:?905 R:R:F373 54.36057.65YesYes005
52R:R:F373 R:R:I376 53.10945.02YesNo053
53R:R:I376 R:R:P461 53.0335.08NoYes032
54R:R:H311 R:R:P461 24.02953.05NoYes242
55R:R:H311 R:R:W455 23.944312.7NoNo043
56R:R:F322 R:R:W455 23.63596.01YesNo073
57R:R:F322 R:R:W298 42.252214.03YesYes278
58R:R:L264 R:R:W298 19.5433.42YesYes278
59R:R:I207 R:R:L264 18.9297.14YesYes287
60R:R:F236 R:R:I207 19.82516.33NoYes268
61R:R:E238 R:R:F236 19.55364.66YesNo256
62R:R:E238 S:S:H515 13.63163.69YesNo056
63R:R:F462 R:R:P461 28.58324.33YesYes242
64R:R:F462 R:R:W453 27.11929.02YesNo245
65R:R:F322 R:R:W453 23.973610.02YesNo275
66R:R:V272 R:R:W298 19.17486.13YesYes268
67R:R:I207 R:R:V272 19.26196.14YesYes286
68R:R:A269 R:R:W205 19.99453.89NoYes079
69R:R:A269 R:R:I207 20.36393.25NoYes078
70S:S:E301 S:S:L325 82.40813.98NoNo085
71S:S:K457 S:S:L325 81.28717.05NoNo055
72S:S:D455 S:S:K457 81.11475.53YesNo075
73S:S:D455 S:S:R473 80.64315.96YesYes2373
74S:S:R473 S:S:R479 80.37076.4YesNo033
75H:H:?901 S:S:R479 80.19773.27YesNo003
76H:H:?901 R:R:F525 79.79124.37YesYes1007
77R:R:C538 R:R:F525 79.55732.79YesYes1097
78R:R:C538 R:R:C551 78.98367.28YesNo1099
79R:R:C551 R:R:S544 78.93571.72NoNo098
80R:R:E548 R:R:S544 78.84868.62NoNo058
81R:R:E548 R:R:Y545 78.56148.98NoNo4957
82R:R:D712 R:R:Y545 78.48725.75YesNo047
83R:R:D712 R:R:P713 78.33853.22YesYes044
84R:R:P713 R:R:R554 77.95064.32YesYes2748
85R:R:R554 R:R:T716 77.81425.17YesNo087
86R:R:T706 R:R:T716 77.72673.14NoNo037
87R:R:T706 R:R:V718 77.63921.59NoNo037
88R:R:P625 R:R:V718 77.4645.3NoNo097
89R:R:P625 R:R:T629 77.02561.75NoNo096
90R:R:C630 R:R:T629 76.76213.38NoNo096
91R:R:C630 R:R:C720 76.67427.28NoNo099
92R:R:C720 R:R:R633 75.15218.36NoNo098
93R:R:R633 R:R:Y621 74.783928.81NoYes088
94R:R:L793 R:R:Y621 43.52867.03NoYes088
95R:R:L793 R:R:V569 43.42952.98NoNo088
96R:R:I790 R:R:V569 43.13273.07NoNo088
97R:R:I790 R:R:L787 42.8364.28NoNo085
98R:R:L787 R:R:Y783 42.73725.86NoNo058
99R:R:F779 R:R:Y783 41.695314.44NoNo078
100R:R:F779 S:S:W727 41.505620.04NoNo073
101S:S:F730 S:S:W727 41.41087.02NoNo073
102S:S:F730 S:S:H734 41.22146.79NoNo077
103S:S:H734 S:S:W775 37.43812.7NoYes079
104S:S:F778 S:S:W775 16.04633.01YesYes099
105S:S:F778 S:S:L782 14.26849.74YesNo098
106S:S:L782 S:S:R790 14.19117.29NoYes087
107S:S:E717 S:S:R560 12.252313.96NoNo035
108S:S:E717 S:S:T716 12.0037.06NoNo034
109S:S:T716 S:S:W546 11.753820.62NoYes047
110S:S:W775 S:S:Y771 23.04816.75YesYes098
111S:S:N737 S:S:Y771 12.51484.65YesYes078
112S:S:L644 S:S:V617 18.5725.96NoNo085
113S:S:C801 S:S:Y771 10.29154.03NoYes098
114S:S:P643 S:S:V617 17.01965.3YesNo065
115S:S:L616 S:S:P643 16.04723.28NoYes056
116S:S:L616 S:S:V612 15.84661.49NoNo054
117S:S:L587 S:S:V612 15.6461.49YesNo044
118S:S:L587 S:S:L611 14.44258.3YesYes049
119S:S:H810 S:S:L611 12.772714.14YesYes4099
120S:S:F809 S:S:H810 11.63514.71YesYes089
121R:R:F637 R:R:Y621 32.42037.22YesYes088
122R:R:F637 R:R:V618 32.02043.93YesYes087
123R:R:V618 R:R:V797 31.72213.21YesNo079
124R:R:L572 R:R:V797 31.62324.47NoNo039
125R:R:L572 R:R:L801 31.52474.15NoNo036
126R:R:L801 R:R:Y615 31.42624.69NoYes068
127R:R:L800 R:R:Y615 30.14610.55NoYes088
128R:R:F641 R:R:L800 29.94933.65YesNo088
129R:R:F641 R:R:I645 26.25427.54YesNo087
130R:R:I645 R:R:M766 25.86092.92NoNo079
131R:R:I648 R:R:M766 26.0062.92YesNo079
132R:R:I648 R:R:I762 11.06962.94YesYes779
133R:R:A394 R:R:F429 16.39012.77NoYes089
134R:R:A394 R:R:F438 16.41162.77NoNo088
135R:R:F438 R:R:L181 16.34159.74NoYes2686
136R:R:L181 R:R:W425 16.556611.39YesNo065
137R:R:L421 R:R:W425 16.63846.83YesNo065
138R:R:F429 R:R:L431 15.59223.65YesYes397
139R:R:L446 R:R:P185 21.86043.28NoYes058
140R:R:L446 R:R:Y386 21.87363.52NoYes057
141R:R:L431 R:R:Y386 15.5165.86YesYes377
142R:R:C495 R:R:W205 11.885114.37NoYes2099
143R:R:C495 R:R:S496 11.51473.44NoNo098
144R:R:F515 R:R:S496 11.143813.21NoNo078
145R:R:F515 R:R:K505 10.772819.85NoYes078
146R:R:H189 R:R:P185 14.23364.58YesYes1548
Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


PDB Summary
PDB 9NOS
Class C
SubFamily Sensory
Type Taste1
SubType TAS1R2; TAS1R3
Species Homo Sapiens
Ligand -
Other Ligand(s) -
Protein Partners -
PDB Resolution 3.5
Date 2025-04-09
D.O.I. doi.org/10.1016/j.cell.2025.04.021
Net Summary
Imin 2.87
Number of Linked Nodes 1489
Number of Links 1788
Number of Hubs 275
Number of Links mediated by Hubs 974
Number of Communities 52
Number of Nodes involved in Communities 370
Number of Links involved in Communities 510
Path Summary
Number Of Nodes in MetaPath 147
Number Of Links MetaPath 146
Number of Shortest Paths 8691456
Length Of Smallest Path 3
Average Path Length 53.1842
Length of Longest Path 103
Minimum Path Strength 1.24
Average Path Strength 6.56289
Maximum Path Strength 30.805
Minimum Path Correlation 0.71
Average Path Correlation 0.999362
Maximum Path Correlation 1
Minimum % Of Corr. Nodes 1.85185
Average % Of Corr. Nodes 53.5103
Maximum % Of Corr. Nodes 100
Minimum Path Hubs % 0
Average Path Hubs % 45.2684
Maximum Path Hubs % 100
AnnotationTypeLinks
Gene OntologyMolecular Function
Gene OntologyBiological Process• sensory perception of sweet taste   • multicellular organismal process   • system process   • sensory perception of chemical stimulus   • sensory perception   • nervous system process   • sensory perception of taste   • sensory perception of umami taste   • response to stimulus   • detection of chemical stimulus involved in sensory perception of sweet taste   • detection of chemical stimulus involved in sensory perception of taste   • detection of stimulus   • response to chemical   • detection of chemical stimulus   • detection of stimulus involved in sensory perception   • detection of chemical stimulus involved in sensory perception   • cellular response to stimulus   • regulation of biological process   • regulation of cellular process   • signaling   • biological regulation   • G protein-coupled receptor signaling pathway   • cellular process   • signal transduction   • cell communication   • cellular anatomical structure   • membrane   • membrane-bounded organelle   • intracellular organelle   • intracellular anatomical structure   • Golgi apparatus   • organelle   • cytoplasm   • intracellular membrane-bounded organelle   • endomembrane system   • cell periphery   • plasma membrane   • protein-containing complex   • taste receptor complex
Gene OntologyCellular Component• cellular anatomical structure   • membrane   • membrane-bounded organelle   • intracellular organelle   • intracellular anatomical structure   • Golgi apparatus   • organelle   • cytoplasm   • intracellular membrane-bounded organelle   • endomembrane system   • cell periphery   • plasma membrane   • protein-containing complex   • taste receptor complex   • sweet taste receptor complex   • receptor complex   • taste receptor activity   • molecular transducer activity   • transmembrane signaling receptor activity   • signaling receptor activity   • G protein-coupled receptor activity   • sweet taste receptor activity   • sensory perception of sweet taste   • multicellular organismal process   • system process   • sensory perception of chemical stimulus   • sensory perception   • nervous system process   • sensory perception of taste   • regulation of cytokinesis   • regulation of biological process   • regulation of cellular process   • positive regulation of cell division   • regulation of cell cycle process   • biological regulation   • positive regulation of biological process   • cytokinesis   • positive regulation of cell cycle   • regulation of cell division   • positive regulation of cytokinesis   • positive regulation of cell cycle process   • cellular process   • cell division   • cell cycle   • regulation of cell cycle   • positive regulation of cellular process   • cell cycle process   • response to stimulus   • detection of chemical stimulus involved in sensory perception of sweet taste   • detection of chemical stimulus involved in sensory perception of taste   • detection of stimulus   • response to chemical   • detection of chemical stimulus   • detection of stimulus involved in sensory perception   • detection of chemical stimulus involved in sensory perception   • cellular response to stimulus   • signaling   • G protein-coupled receptor signaling pathway   • signal transduction   • cell communication
SCOP2Domain Identifier
SCOP2Family Identifier
Membrane Protein Annotations-• Orientations of Proteins in Membranes database (OPM)   • Protein Data Bank of Transmembrane Proteins (PDBTM)   • MemProtMD


Details about the values in these tables can be found in the corresponding documentation page .
CodeNAG
PDB ResiduesH:H:?901 H:H:?902 H:H:?903 H:H:?904 H:H:?905 H:H:?906 H:H:?907 H:H:?908
Environment DetailsOpen EMBL-EBI Page
CodeNAG
NameN-Acetylglucosamine
SynonymsN-Acetylglucosamine
Identifier
FormulaC8 H15 N O6
Molecular Weight221.208
SMILES
PubChem24139
Formal Charge0
Total Atoms30
Total Chiral Atoms5
Total Bonds30
Total Aromatic Bonds0

PDBsumOpen PDBsum Page
ChainS
ProteinReceptor
UniProtQ7RTX0
Sequence
>9NOS_Chain_S
LCLSQQLRM KGDYVLGGL FPLGEARTR PSSPVCTRF SSNGLLWAL 
AMKMAVEEI NNKSDLLPG LRLGYDLFD TCSEPVVAM KPSLMFLAK 
AGSRDIAAY CNYTQYQPR VLAVIGPHS SELAMVTGK FFSFFLMPQ 
VSYGASMEL LSARETFPS FFRTVPSDR VQLTAAAEL LQEFGWNWV 
AALGSDDEY GRQGLSIFS ALAAARGIC IAHEGLVPL PKVQDVLHQ 
VNQSSVQVV LLFASVHAA HALFNYSIS SRLSPKVWV ASEAWLTSD 
LVMGLPGMA QMGTVLGFL QRGAQLHEF PQYVKTHLA LATDPAFCS 
ALQRCPQCD CITLQNVSA GLNHHQTFS VYAAVYSVA QALHNTLQC 
NASGCPAQD PVKPWQLLE NMYNLTFHV GGLPLRFDS SGNVDMEYD 
LKLWVWQGS VPRLHDVGR FNGSLRTER LKIRWHTSD NQKPVSRCS 
RQCQEGQVR RVKGFHSCC YDCVDCEAG SYRQNPDDI ACTFCGQDE 
WSPERSTRC FRRRSRFLA WGEPAVLLL LLLLSLALG LVLAALGLF 
VHHRDSPLV QASGGPLAC FGLVCLGLV CLSVLLFPG QPSPARCLA 
QQPLSHLPL TGCLSTLFL QAAEIFVES ELPLSWADR LSGCLRGPW 
AWLVVLLAM LVEVALCTW YLVAFPPEV VTDWHMLPT EALVHCRTR 
SWVSFGLAH ATNATLAFL CFLGTFLVR SQPGYNRAR GLTFAMLAY 
FITWVSFVP LLANVQVVL RPAVQMGAL LLCVLGILA AFHLPRCYL 
LMRQPGLNT PEFFLR


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

ChainR
ProteinReceptor
UniProtQ8TE23
Sequence
>9NOS_Chain_R
YFSFASCVC CLPCLVSDF YLPGDYLLG GLFSLHANM KNFLQVPMC 
KEYEVKVIG YNLMQAMRF AVEEINNDS SLLPGVLLG YEIVDVCYI 
SNNVQPVLY FLAHEDNLL PIQEDSNYI SRVVAVIGP DNSESVMTV 
ANFLSLLLP QITYSAISD ELRDKVRFP ALLRTTPSA DHHIEAMVQ 
LMLHFRWNW IIVLVSSDT YGRDNGQLL GERVARRDI CIAFQETLP 
TLQPNQNMT SEERQRLVT IVDKLQQST ARVVVVFPD LTLYHFNEV 
LRQNFTGAV WIASESWAI DPVLHNLTE LRHLGTFLG ITIQSVPIP 
GFSEFREWG TCNQECDNC LNATLSFNT ILRLSGERV VYSVYSAVY 
AVHALHSLL GCDKSTCTK RVVYPWQLL EEIWKVNFT LLDHQIFFD 
PQGDVALHL EIVQWQWDR SQNPFQVAS YYPLQRQLK NIQDISWHT 
INNTIPMSM CSKRQSGQK KKPGIHVCC FEIDCLPGT FLNHTEDEY 
ECQAPNNEW SYQSETSCF KRQLVFLEW HEAPTIAVA LLAALGFLS 
TLAILVIFW RHFQTPIVR SAGGPMCFL MLTLLVAYM VVPVYVGPP 
KVSTCLCRQ ALFLCFTIC ISIAVRSFQ IVCAFKMAS RFPRAYSYW 
VRYQGPYVS MAFITVLKM VIVVIGMLA TGLSPTTRT DPDDPKITI 
VSCNPNYRN SLLFNTSLD LLLSVVGFS FAYMGKELP TNYNEAKFI 
TSMTFYFTS SVSLCTFMS AYSGVLTIV DLLVTVLNL LAISLGYFG 
PKCYMILFY PERNTPAYF NS


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  




This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
9NOXCSensoryTaste1TAS1R2Homo sapiens--chim(Gs-CtGt3)/β1/γ232025-04-09doi.org/10.1016/j.cell.2025.04.021
9NOX (No Gprot) CSensoryTaste1TAS1R2Homo sapiens--32025-04-09doi.org/10.1016/j.cell.2025.04.021
9NOYCSensoryTaste1TAS1R2Homo sapiens---3.72025-04-09doi.org/10.1016/j.cell.2025.04.021
9NORCSensoryTaste1TAS1R2; TAS1R3Homo sapiens---3.42025-04-09doi.org/10.1016/j.cell.2025.04.021
9NOSCSensoryTaste1TAS1R2; TAS1R3Homo sapiens---3.52025-04-09doi.org/10.1016/j.cell.2025.04.021
9NOTCSensoryTaste1TAS1R2; TAS1R3Homo sapiens---3.82025-04-09doi.org/10.1016/j.cell.2025.04.021
9O38CSensoryTaste1TAS1R2; TAS1R3Homo sapiens--chim(Gs-CtGt3)/β1/γ232025-04-09doi.org/10.1016/j.cell.2025.04.021
9O38 (No Gprot) CSensoryTaste1TAS1R2; TAS1R3Homo sapiens--32025-04-09doi.org/10.1016/j.cell.2025.04.021
9OQ0CSensoryTaste1TAS1R2; TAS1R3Homo sapiens; mus musculus---3.672025-08-27To be published
9UT8CSensoryTaste1TAS1R2; TAS1R3Homo sapiens---3.412025-07-16doi.org/10.1038/s41586-025-09302-6
9UTACSensoryTaste1TAS1R2; TAS1R3Homo sapiens---3.772025-07-16doi.org/10.1038/s41586-025-09302-6
9UTBCSensoryTaste1TAS1R2; TAS1R3Homo sapiensSucralose--3.592025-07-16doi.org/10.1038/s41586-025-09302-6




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