Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index Hub Avg Int. Strength Num Of Links Community ConSurf
1S:S:S26 3.584295
2S:S:Y35 6.58254245
3S:S:L40 6.26416
4S:S:F41 5.884548
5S:S:N68 4.4425444
6S:S:L71 3.3325446
7S:S:W72 8.49167645
8S:S:M76 4.8475448
9S:S:K77 7.318545
10S:S:E81 5.24447
11S:S:L89 5.4854187
12S:S:R94 3.415406
13S:S:Y97 8.998548
14S:S:L99 5.755447
15S:S:F100 10.1075404
16S:S:K111 6.4725405
17S:S:F116 6.038505
18S:S:L117 6.744514
19S:S:N130 11.24254194
20S:S:Q133 8.1454192
21S:S:V141 5.44417
22S:S:P144 8.5625415
23S:S:H145 8.414545
24S:S:L149 4.18667613
25S:S:T153 5.744516
26S:S:F156 6.042514
27S:S:F157 5.65143717
28S:S:F159 6.815415
29S:S:F160 13415
30S:S:L161 5.8854344
31S:S:M162 3.68286716
32S:S:Q164 5.96617
33S:S:Y167 8.97447
34S:S:F180 4.7575406
35S:S:F183 6.788508
36S:S:F184 9.75754136
37S:S:P188 8.1525437
38S:S:D190 6.9925438
39S:S:Q193 3.95439
40S:S:E203 6.25435
41S:S:F204 7.75167638
42S:S:W206 12.12439
43S:S:W208 6.5865149
44S:S:S214 5.2125437
45S:S:D216 6.16436
46S:S:Y218 6.85667638
47S:S:F226 5.2875406
48S:S:R233 5.5645364
49S:S:I237 4.9575425
50S:S:E240 6.71667625
51S:S:F274 8.215637
52S:S:F284 8.364394
53S:S:Y286 8.4025406
54S:S:W303 9.095397
55S:S:M318 3.765406
56S:S:T320 3.924538
57S:S:F324 6.5375436
58S:S:Y337 11.625447
59S:S:V338 3.545406
60S:S:H341 9.5625444
61S:S:C370 5.3954298
62S:S:H387 7.365445
63S:S:Q389 6.22167644
64S:S:Y394 11.284338
65S:S:Y398 10.924338
66S:S:S399 4.864138
67S:S:L404 7.484247
68S:S:H405 3.39254187
69S:S:L408 4.734244
70S:S:K422 6.79413
71S:S:L433 3.4525136
72S:S:F435 7.2065139
73S:S:F444 5.5345139
74S:S:N449 6.3125357
75S:S:Y454 5.626538
76S:S:D455 7.4425467
77S:S:L456 6.4425437
78S:S:W459 7.15406
79S:S:V471 4.92408
80S:S:R473 8.8625463
81S:S:F474 5.135436
82S:S:W487 6.5175838
83S:S:H488 5.716504
84S:S:P495 6.39437
85S:S:C499 5.3754149
86S:S:Q507 6.4885217
87S:S:W546 11.5075407
88S:S:S547 4.33488
89S:S:C554 6.3975489
90S:S:F561 5.89754226
91S:S:L562 3.97754428
92S:S:L572 3.0025408
93S:S:F590 4.8445159
94S:S:L598 6.5025407
95S:S:L611 7.55254159
96S:S:V621 6.3725407
97S:S:P625 3.9654427
98S:S:Q636 5.974448
99S:S:P643 3.9075406
100S:S:L644 3.26408
101S:S:L653 3.1875407
102S:S:E663 5.684456
103S:S:L664 2.675406
104S:S:Y699 6.3645166
105S:S:F703 6.5685165
106S:S:W711 6.0225403
107S:S:E717 9.82403
108S:S:V720 5.8454226
109S:S:H721 5.364126
110S:S:N737 4.75407
111S:S:F742 4.5403
112S:S:F745 5.89409
113S:S:L750 6.614458
114S:S:Y758 6.80754439
115S:S:R762 5.28409
116S:S:M768 4.7825409
117S:S:V787 5.115127
118S:S:R790 4.91254127
119S:S:M795 5.355407
120S:S:L806 3.4925408
121S:S:F809 8.016508
122S:S:H810 9.34754159
123S:S:R813 7.3875409
124S:S:F829 6.366436
125R:R:Y33 4.195405
126R:R:L38 5.63667617
127R:R:F39 6.158558
128R:R:L41 5.854555
129R:R:H42 5.3225457
130R:R:F53 5.4275402
131R:R:Y62 8.8675401
132R:R:V64 4.4875404
133R:R:L71 4.19555
134R:R:M72 5.6825455
135R:R:M75 4.256558
136R:R:F77 6.035408
137R:R:Y96 8.9675408
138R:R:I98 5.38457
139R:R:P110 4.99515
140R:R:F114 4.895416
141R:R:L115 5.726515
142R:R:L122 4.095414
143R:R:P123 5.2625413
144R:R:Y128 9.232504
145R:R:Y131 8.545414
146R:R:P141 5.672516
147R:R:V147 5.6375418
148R:R:V150 4.58517
149R:R:F153 5.16667614
150R:R:L154 5.1875416
151R:R:F157 9.024517
152R:R:L158 4.16254304
153R:R:L159 5.9875416
154R:R:Q161 5.694518
155R:R:T163 4.9275418
156R:R:Y164 6.958557
157R:R:I167 6.1975428
158R:R:L171 4.865417
159R:R:R172 11.4025418
160R:R:F177 6.37333615
161R:R:L180 4.54167618
162R:R:R182 7.264519
163R:R:P185 3.8154178
164R:R:H189 8.33754174
165R:R:E192 6.6085173
166R:R:M198 4.0775407
167R:R:F201 8.17833698
168R:R:W203 6.99167699
169R:R:W205 8.153336269
170R:R:I207 6.906528
171R:R:V208 4.5575405
172R:R:Y215 5.94714727
173R:R:R217 5.3156206
174R:R:N219 7.4825427
175R:R:R226 7.025404
176R:R:R230 4.4725404
177R:R:F236 9.21426
178R:R:E238 6.288525
179R:R:L264 5.295427
180R:R:Q266 5.234401
181R:R:V271 6.2725498
182R:R:V272 5.3025426
183R:R:F275 6.50667608
184R:R:S276 5.5975424
185R:R:P277 3.6275425
186R:R:L281 5.5475424
187R:R:F284 4.49833624
188R:R:F285 5.18833624
189R:R:E287 7.11754275
190R:R:V288 4.2125404
191R:R:Q291 6.49754274
192R:R:F293 5.55333623
193R:R:W298 5.79625828
194R:R:I299 4.51407
195R:R:W304 7.17627
196R:R:D307 7.73405
197R:R:H311 7.275424
198R:R:L316 5.79524
199R:R:L319 4.44526
200R:R:F322 7.66727
201R:R:V330 7.174104
202R:R:F335 6.7425458
203R:R:Q361 6.9125402
204R:R:F373 6.51405
205R:R:R383 5.3825425
206R:R:V385 6.102556
207R:R:Y386 6.1056107
208R:R:Y389 5.646676108
209R:R:Y393 8.2125108
210R:R:L403 3.64234
211R:R:C405 5.52754235
212R:R:C410 4.414235
213R:R:W418 8.595313
214R:R:L420 4.895477
215R:R:L421 5.464306
216R:R:I424 3.87254487
217R:R:F429 9.474509
218R:R:L431 7.19754107
219R:R:L432 4.40254104
220R:R:Q435 5.024253
221R:R:F437 3.9845254
222R:R:W453 7.7275425
223R:R:P461 4.162522
224R:R:F462 6.465424
225R:R:Y468 6.4756175
226R:R:P470 6.69754173
227R:R:R473 7.14754174
228R:R:I481 6.6325497
229R:R:W483 8.94833698
230R:R:P491 5.622509
231R:R:Q503 8.05754506
232R:R:H511 7.0454267
233R:R:C514 4.9454269
234R:R:T524 4.11254517
235R:R:F525 4.9325467
236R:R:N527 13.8525468
237R:R:C538 6.7875469
238R:R:E542 10.305466
239R:R:C551 6.3075469
240R:R:F558 5.39754527
241R:R:F577 4.9175406
242R:R:T593 3.9625409
243R:R:P594 3.705408
244R:R:M607 6.87408
245R:R:Y615 6.1525408
246R:R:V618 3.5154537
247R:R:Y621 11.9525408
248R:R:R633 11.005408
249R:R:Q634 5.825408
250R:R:F637 4.745408
251R:R:C640 2.4675407
252R:R:F641 6.5365118
253R:R:I643 5.195407
254R:R:I645 4.0625407
255R:R:R651 5.36333679
256R:R:V656 3.3375407
257R:R:F665 4.26405
258R:R:Y669 3.364507
259R:R:W672 6.405476
260R:R:P678 5.208578
261R:R:K689 7.282509
262R:R:D712 6.0325404
263R:R:I715 7.45404
264R:R:V718 3.07754527
265R:R:N721 5.6585556
266R:R:Y724 5.5954558
267R:R:L736 4.33754116
268R:R:N755 6.8125478
269R:R:E758 8.035479
270R:R:I762 3.9025479
271R:R:Y769 7.3125118
272R:R:N799 7.99254119
273R:R:I803 3.39754548
274R:R:Y807 7.754578
275R:R:I815 5.2225408
276H:H:?901 14.6583660
277H:H:?902 13.648500
278H:H:?904 11.57250
279H:H:?905 14.054500
280H:H:?906 16.93254190
281H:H:?907 14.5225320
   

Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index Node1 Node2 Recurrence Int. Strength Hub1? Hub2? Community ConSurf1 ConSurf2
1S:S:L74 S:S:V338 10.26012.98NoYes076
2S:S:N68 S:S:S67 18.53442.98YesNo441
3S:S:N68 S:S:W72 11.75545.65YesYes445
4S:S:F41 S:S:Y167 11.052512.38YesYes487
5S:S:F156 S:S:F157 13.40785.36YesYes147
6S:S:F183 S:S:Q164 23.244411.71YesYes087
7S:S:G168 S:S:H145 14.56254.77NoYes455
8S:S:F183 S:S:L174 30.338310.96YesNo088
9S:S:G168 S:S:V187 22.55235.52NoNo057
10S:S:S392 S:S:V187 11.42064.85NoNo077
11S:S:P188 S:S:V187 34.03983.53YesNo077
12S:S:P188 S:S:Y454 34.17359.74YesYes378
13S:S:Q193 S:S:Y454 37.96623.38YesYes398
14S:S:D190 S:S:Q193 18.64033.92YesYes389
15S:S:F274 S:S:Q193 19.64484.68YesYes379
16S:S:F274 S:S:L194 64.415910.96YesNo076
17S:S:I225 S:S:L194 32.37214.28NoNo036
18S:S:I225 S:S:R191 32.17227.52NoNo033
19S:S:E172 S:S:R191 32.135315.12NoNo053
20S:S:E172 S:S:S175 16.0725.75NoNo059
21S:S:E172 S:S:S189 16.02945.75NoNo058
22S:S:L174 S:S:R185 31.75474.86NoNo089
23S:S:N449 S:S:R185 31.82979.64YesNo079
24S:S:N449 S:S:S175 15.99168.94YesNo3579
25S:S:N449 S:S:S189 15.99164.47YesNo078
26S:S:D190 S:S:Y218 18.70688.05YesYes388
27S:S:F274 S:S:Y218 82.069816.5YesYes378
28S:S:F226 S:S:L194 34.26753.65YesNo066
29S:S:F226 S:S:I237 33.99283.77YesYes065
30S:S:E240 S:S:I237 34.10629.56YesYes255
31S:S:E240 S:S:H515 13.73813.69YesNo256
32R:R:E238 S:S:H515 14.74453.69YesNo256
33R:R:E238 R:R:F236 13.52054.66YesYes256
34R:R:F236 R:R:I207 12.624216.33YesYes268
35S:S:D216 S:S:Y218 50.45944.6YesYes368
36S:S:D216 S:S:S214 50.44958.83YesYes367
37S:S:A275 S:S:S214 1003.42NoYes047
38S:S:A275 S:S:L273 1003.15NoNo045
39S:S:L273 S:S:W303 10013.67NoYes057
40S:S:F284 S:S:W303 10010.02YesYes3947
41S:S:G219 S:S:Y218 50.39332.9NoYes088
42S:S:G219 S:S:S214 50.3953.71NoYes087
43S:S:E240 S:S:F514 20.23085.83YesNo254
44S:S:F284 S:S:M315 99.80027.46YesNo044
45S:S:M315 S:S:W459 99.57053.49NoYes046
46S:S:L468 S:S:W459 99.42943.42NoYes056
47S:S:K457 S:S:L468 99.36454.23NoNo055
48S:S:D455 S:S:K457 99.35075.53YesNo075
49S:S:D455 S:S:R327 49.626113.1YesNo675
50S:S:E453 S:S:R327 49.60143.49NoNo645
51S:S:D455 S:S:R473 49.6937.15YesYes673
52S:S:E453 S:S:R473 49.6196.98NoYes643
53S:S:E453 S:S:N475 99.16236.57NoNo644
54H:H:?901 S:S:N475 99.037127.11YesNo604
55H:H:?901 R:R:Q536 98.80423.58YesNo601
56R:R:F525 R:R:Q536 98.77235.86YesNo671
57R:R:C551 R:R:F525 98.1955.59YesYes697
58R:R:C551 R:R:S544 97.97891.72YesNo098
59R:R:E548 R:R:S544 97.92058.62NoNo058
60R:R:E548 R:R:Y545 48.9317.86NoNo2857
61R:R:K714 R:R:Y545 48.86833.58NoNo2847
62R:R:D712 R:R:K714 97.60666.91YesNo044
63R:R:D712 R:R:I715 94.86718.4YesYes044
64R:R:I715 R:R:V557 94.35056.14YesNo045
65R:R:I717 R:R:V557 94.22033.07NoNo065
66R:R:I717 R:R:V786 93.82963.07NoNo068
67R:R:L787 R:R:V786 93.69932.98NoNo058
68R:R:L787 R:R:Y783 92.39595.86NoNo058
69R:R:F779 R:R:Y783 92.135115.47NoNo078
70R:R:F779 S:S:W727 91.874217.04NoNo073
71S:S:F730 S:S:W727 91.74388.02NoNo073
72S:S:F730 S:S:H734 91.48287.92NoNo077
73S:S:H734 S:S:W775 88.701716.93NoNo079
74S:S:W775 S:S:Y771 88.309515.43NoNo098
75S:S:N737 S:S:Y771 35.67374.65YesNo078
76S:S:L644 S:S:N737 34.89074.12YesYes087
77S:S:L644 S:S:V617 32.99042.98YesNo085
78S:S:V617 S:S:V802 29.60053.21NoNo058
79S:S:C618 S:S:V802 29.46485.12NoNo088
80S:S:C618 S:S:L799 28.86413.17NoNo088
81S:S:L799 S:S:V621 28.591710.43NoYes087
82S:S:M795 S:S:V621 27.63567.61YesYes077
83S:S:M795 S:S:P625 24.21313.35YesYes077
84S:S:L562 S:S:P625 23.66794.93YesYes4287
85S:S:L562 S:S:P791 23.53824.93YesNo086
86S:S:P791 S:S:R790 23.40162.88NoYes067
87S:S:H721 S:S:R790 11.4297.9YesYes1267
88S:S:H721 S:S:L719 10.88013.86YesNo1267
89S:S:L714 S:S:L719 21.48522.77NoNo037
90S:S:T716 S:S:W546 18.732718.19NoYes047
91R:R:E548 R:R:F552 48.9314.66NoNo2854
92R:R:F552 R:R:K714 48.86839.93NoNo2844
93S:S:R790 S:S:V787 11.4295.23YesYes1277
94S:S:L719 S:S:V787 10.88012.98NoYes1277
95S:S:E717 S:S:L714 11.29386.63YesNo033
96R:R:Q237 S:S:F514 21.246712.88NoNo054
97S:S:F772 S:S:Y771 52.52435.16NoNo068
98S:S:A741 S:S:F772 51.72092.77NoNo086
99S:S:A741 S:S:M768 51.58993.22NoYes089
100S:S:F745 S:S:M768 44.73354.98YesYes099
101S:S:F745 S:S:F749 43.37159.65YesNo098
102R:R:T767 S:S:F749 38.89433.89NoNo088
103R:R:I648 R:R:M766 21.69182.92NoNo079
104R:R:I648 R:R:I762 21.75794.42NoYes779
105R:R:A746 R:R:I762 35.37633.25NoYes799
106R:R:A746 R:R:T763 38.4033.36NoNo099
107R:R:F743 R:R:T763 38.53895.19NoNo089
108R:R:F743 R:R:T767 38.75863.89NoNo088
109R:R:L223 R:R:V208 12.6882.98NoYes065
110R:R:Q237 R:R:V208 21.13514.3NoYes055
111R:R:I191 R:R:R226 11.18446.26NoYes064
112R:R:I191 R:R:L223 11.25025.71NoNo066
113R:R:L446 R:R:P185 10.85473.28NoYes058
114R:R:I645 R:R:M766 13.67682.92YesNo079
115R:R:I762 R:R:Y807 13.49224.84YesYes798
116R:R:K689 R:R:T642 10.524616.52YesNo098
117R:R:D735 R:R:T642 10.80147.23NoNo088
118S:S:H145 S:S:Y167 10.60387.62YesYes457
119R:R:L446 R:R:Y386 10.74.69NoYes057
120S:S:F157 S:S:Q164 20.08735.86YesYes177
Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


PDB Summary
PDB 9NOR
Class C
SubFamily Sensory
Type Taste1
SubType TAS1R2; TAS1R3
Species Homo Sapiens
Ligand -
Other Ligand(s) -
Protein Partners -
PDB Resolution 3.4
Date 2025-04-09
D.O.I. doi.org/10.1016/j.cell.2025.04.021
Net Summary
Imin 2.89
Number of Linked Nodes 1493
Number of Links 1803
Number of Hubs 281
Number of Links mediated by Hubs 991
Number of Communities 55
Number of Nodes involved in Communities 396
Number of Links involved in Communities 542
Path Summary
Number Of Nodes in MetaPath 121
Number Of Links MetaPath 120
Number of Shortest Paths 19542269
Length Of Smallest Path 3
Average Path Length 67.6477
Length of Longest Path 92
Minimum Path Strength 1.18
Average Path Strength 8.00592
Maximum Path Strength 33.27
Minimum Path Correlation 0.7
Average Path Correlation 1
Maximum Path Correlation 1
Minimum % Of Corr. Nodes 1.88679
Average % Of Corr. Nodes 63.2543
Maximum % Of Corr. Nodes 100
Minimum Path Hubs % 0
Average Path Hubs % 51.7411
Maximum Path Hubs % 100
AnnotationTypeLinks
Gene OntologyMolecular Function
Gene OntologyBiological Process• sensory perception of sweet taste   • multicellular organismal process   • system process   • sensory perception of chemical stimulus   • sensory perception   • nervous system process   • sensory perception of taste   • sensory perception of umami taste   • response to stimulus   • detection of chemical stimulus involved in sensory perception of sweet taste   • detection of chemical stimulus involved in sensory perception of taste   • detection of stimulus   • response to chemical   • detection of chemical stimulus   • detection of stimulus involved in sensory perception   • detection of chemical stimulus involved in sensory perception   • cellular response to stimulus   • regulation of biological process   • regulation of cellular process   • signaling   • biological regulation   • G protein-coupled receptor signaling pathway   • cellular process   • signal transduction   • cell communication   • cellular anatomical structure   • membrane   • membrane-bounded organelle   • intracellular organelle   • intracellular anatomical structure   • Golgi apparatus   • organelle   • cytoplasm   • intracellular membrane-bounded organelle   • endomembrane system   • cell periphery   • plasma membrane   • protein-containing complex   • taste receptor complex
Gene OntologyCellular Component• cellular anatomical structure   • membrane   • membrane-bounded organelle   • intracellular organelle   • intracellular anatomical structure   • Golgi apparatus   • organelle   • cytoplasm   • intracellular membrane-bounded organelle   • endomembrane system   • cell periphery   • plasma membrane   • protein-containing complex   • taste receptor complex   • sweet taste receptor complex   • receptor complex   • taste receptor activity   • molecular transducer activity   • transmembrane signaling receptor activity   • signaling receptor activity   • G protein-coupled receptor activity   • sweet taste receptor activity   • sensory perception of sweet taste   • multicellular organismal process   • system process   • sensory perception of chemical stimulus   • sensory perception   • nervous system process   • sensory perception of taste   • regulation of cytokinesis   • regulation of biological process   • regulation of cellular process   • positive regulation of cell division   • regulation of cell cycle process   • biological regulation   • positive regulation of biological process   • cytokinesis   • positive regulation of cell cycle   • regulation of cell division   • positive regulation of cytokinesis   • positive regulation of cell cycle process   • cellular process   • cell division   • cell cycle   • regulation of cell cycle   • positive regulation of cellular process   • cell cycle process   • response to stimulus   • detection of chemical stimulus involved in sensory perception of sweet taste   • detection of chemical stimulus involved in sensory perception of taste   • detection of stimulus   • response to chemical   • detection of chemical stimulus   • detection of stimulus involved in sensory perception   • detection of chemical stimulus involved in sensory perception   • cellular response to stimulus   • signaling   • G protein-coupled receptor signaling pathway   • signal transduction   • cell communication
SCOP2Domain Identifier
SCOP2Family Identifier
Membrane Protein Annotations-• Orientations of Proteins in Membranes database (OPM)   • Protein Data Bank of Transmembrane Proteins (PDBTM)   • MemProtMD


Details about the values in these tables can be found in the corresponding documentation page .
CodeNAG
PDB ResiduesH:H:?901 H:H:?902 H:H:?903 H:H:?904 H:H:?905 H:H:?906 H:H:?907 H:H:?908
Environment DetailsOpen EMBL-EBI Page
CodeNAG
NameN-Acetylglucosamine
SynonymsN-Acetylglucosamine
Identifier
FormulaC8 H15 N O6
Molecular Weight221.208
SMILES
PubChem24139
Formal Charge0
Total Atoms30
Total Chiral Atoms5
Total Bonds30
Total Aromatic Bonds0

PDBsumOpen PDBsum Page
ChainS
ProteinReceptor
UniProtQ7RTX0
Sequence
>9NOR_Chain_S
LCLSQQLRM KGDYVLGGL FPLGEARTR PSSPVCTRF SSNGLLWAL 
AMKMAVEEI NNKSDLLPG LRLGYDLFD TCSEPVVAM KPSLMFLAK 
AGSRDIAAY CNYTQYQPR VLAVIGPHS SELAMVTGK FFSFFLMPQ 
VSYGASMEL LSARETFPS FFRTVPSDR VQLTAAAEL LQEFGWNWV 
AALGSDDEY GRQGLSIFS ALAAARGIC IAHEGLVPL PKVQDVLHQ 
VNQSSVQVV LLFASVHAA HALFNYSIS SRLSPKVWV ASEAWLTSD 
LVMGLPGMA QMGTVLGFL QRGAQLHEF PQYVKTHLA LATDPAFCS 
ALQRCPQCD CITLQNVSA GLNHHQTFS VYAAVYSVA QALHNTLQC 
NASGCPAQD PVKPWQLLE NMYNLTFHV GGLPLRFDS SGNVDMEYD 
LKLWVWQGS VPRLHDVGR FNGSLRTER LKIRWHTSD NQKPVSRCS 
RQCQEGQVR RVKGFHSCC YDCVDCEAG SYRQNPDDI ACTFCGQDE 
WSPERSTRC FRRRSRFLA WGEPAVLLL LLLLSLALG LVLAALGLF 
VHHRDSPLV QASGGPLAC FGLVCLGLV CLSVLLFPG QPSPARCLA 
QQPLSHLPL TGCLSTLFL QAAEIFVES ELPLSWADR LSGCLRGPW 
AWLVVLLAM LVEVALCTW YLVAFPPEV VTDWHMLPT EALVHCRTR 
SWVSFGLAH ATNATLAFL CFLGTFLVR SQPGYNRAR GLTFAMLAY 
FITWVSFVP LLANVQVVL RPAVQMGAL LLCVLGILA AFHLPRCYL 
LMRQPGLNT PEFFLR


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

ChainR
ProteinReceptor
UniProtQ8TE23
Sequence
>9NOR_Chain_R
YFSFASCVC CLPCLVSDF YLPGDYLLG GLFSLHANM KNFLQVPMC 
KEYEVKVIG YNLMQAMRF AVEEINNDS SLLPGVLLG YEIVDVCYI 
SNNVQPVLY FLAHEDNLL PIQEDSNYI SRVVAVIGP DNSESVMTV 
ANFLSLLLP QITYSAISD ELRDKVRFP ALLRTTPSA DHHIEAMVQ 
LMLHFRWNW IIVLVSSDT YGRDNGQLL GERVARRDI CIAFQETLP 
TLQPNQNMT SEERQRLVT IVDKLQQST ARVVVVFPD LTLYHFNEV 
LRQNFTGAV WIASESWAI DPVLHNLTE LRHLGTFLG ITIQSVPIP 
GFSEFREWG TCNQECDNC LNATLSFNT ILRLSGERV VYSVYSAVY 
AVHALHSLL GCDKSTCTK RVVYPWQLL EEIWKVNFT LLDHQIFFD 
PQGDVALHL EIVQWQWDR SQNPFQVAS YYPLQRQLK NIQDISWHT 
INNTIPMSM CSKRQSGQK KKPGIHVCC FEIDCLPGT FLNHTEDEY 
ECQAPNNEW SYQSETSCF KRQLVFLEW HEAPTIAVA LLAALGFLS 
TLAILVIFW RHFQTPIVR SAGGPMCFL MLTLLVAYM VVPVYVGPP 
KVSTCLCRQ ALFLCFTIC ISIAVRSFQ IVCAFKMAS RFPRAYSYW 
VRYQGPYVS MAFITVLKM VIVVIGMLA TGLSPTTRT DPDDPKITI 
VSCNPNYRN SLLFNTSLD LLLSVVGFS FAYMGKELP TNYNEAKFI 
TSMTFYFTS SVSLCTFMS AYSGVLTIV DLLVTVLNL LAISLGYFG 
PKCYMILFY PERNTPAYF NS


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  




This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
9NOXCSensoryTaste1TAS1R2Homo sapiens--chim(Gs-CtGt3)/β1/γ232025-04-09doi.org/10.1016/j.cell.2025.04.021
9NOX (No Gprot) CSensoryTaste1TAS1R2Homo sapiens--32025-04-09doi.org/10.1016/j.cell.2025.04.021
9NOYCSensoryTaste1TAS1R2Homo sapiens---3.72025-04-09doi.org/10.1016/j.cell.2025.04.021
9NORCSensoryTaste1TAS1R2; TAS1R3Homo sapiens---3.42025-04-09doi.org/10.1016/j.cell.2025.04.021
9NOSCSensoryTaste1TAS1R2; TAS1R3Homo sapiens---3.52025-04-09doi.org/10.1016/j.cell.2025.04.021
9NOTCSensoryTaste1TAS1R2; TAS1R3Homo sapiens---3.82025-04-09doi.org/10.1016/j.cell.2025.04.021
9O38CSensoryTaste1TAS1R2; TAS1R3Homo sapiens--chim(Gs-CtGt3)/β1/γ232025-04-09doi.org/10.1016/j.cell.2025.04.021
9O38 (No Gprot) CSensoryTaste1TAS1R2; TAS1R3Homo sapiens--32025-04-09doi.org/10.1016/j.cell.2025.04.021
9OQ0CSensoryTaste1TAS1R2; TAS1R3Homo sapiens; mus musculus---3.672025-08-27To be published
9UT8CSensoryTaste1TAS1R2; TAS1R3Homo sapiens---3.412025-07-16doi.org/10.1038/s41586-025-09302-6
9UTACSensoryTaste1TAS1R2; TAS1R3Homo sapiens---3.772025-07-16doi.org/10.1038/s41586-025-09302-6
9UTBCSensoryTaste1TAS1R2; TAS1R3Homo sapiensSucralose--3.592025-07-16doi.org/10.1038/s41586-025-09302-6




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