psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:R554	R:R:T708	6.47	No	No	0	8	4
2	R:R:L556	R:R:V718	2.98	No	No	0	4	7
3	R:R:E560	R:R:F558	10.49	No	No	0	6	7
4	R:R:F558	R:R:P624	14.45	No	No	0	7	5
5	R:R:F558	R:R:P625	4.33	No	No	0	7	9
6	R:R:E563	R:R:L559	2.65	No	Yes	7	8	8
7	R:R:L559	R:R:T566	4.42	Yes	No	7	8	7
8	R:R:L559	R:R:V622	4.47	Yes	Yes	7	8	7
9	R:R:L559	R:R:T789	2.95	Yes	No	0	8	7
10	R:R:I790	R:R:L559	4.28	No	Yes	0	8	8
11	R:R:E560	R:R:H562	4.92	No	No	0	6	3
12	R:R:I567	R:R:W561	3.52	No	No	0	6	5
13	R:R:A570	R:R:W561	3.89	No	No	0	5	5
14	R:R:V622	R:R:W561	14.71	Yes	No	0	7	5
15	R:R:E563	R:R:T566	9.88	No	No	7	8	7
16	R:R:I790	R:R:P565	3.39	No	No	0	8	6
17	R:R:T566	R:R:V622	4.76	No	Yes	7	7	7
18	R:R:I567	R:R:L571	2.85	No	No	0	6	2
19	R:R:V569	R:R:V618	3.21	No	Yes	9	8	7
20	R:R:L793	R:R:V569	2.98	No	No	9	8	8
21	R:R:L794	R:R:V569	2.98	No	No	0	7	8
22	R:R:L572	R:R:V797	2.98	No	No	0	3	9
23	R:R:L572	R:R:L798	2.77	No	No	0	3	7
24	R:R:L572	R:R:L801	4.15	No	No	0	3	6
25	R:R:A573	R:R:V618	3.39	No	Yes	0	7	7
26	R:R:A573	R:R:V797	3.39	No	No	0	7	9
27	R:R:G576	R:R:L575	3.42	No	No	0	6	2
28	R:R:L575	R:R:S579	3	No	No	0	2	4
29	R:R:G576	R:R:Y615	2.9	No	Yes	0	6	8
30	R:R:F577	R:R:L578	3.65	No	No	0	6	3
31	R:R:F577	R:R:L612	4.87	No	Yes	0	6	4
32	R:R:F577	R:R:Y615	8.25	No	Yes	0	6	8
33	R:R:L612	R:R:T580	4.42	Yes	No	0	4	8
34	R:R:T580	R:R:Y615	9.99	No	Yes	0	8	8
35	R:R:S804	R:R:T580	6.4	No	No	0	8	8
36	R:R:L581	R:R:V585	2.98	No	No	0	3	1
37	R:R:I583	R:R:L608	2.85	No	No	0	7	9
38	R:R:C812	R:R:I583	3.27	No	No	0	7	7
39	R:R:L584	R:R:L608	2.77	No	No	0	4	9
40	R:R:L584	R:R:L612	4.15	No	Yes	0	4	4
41	R:R:C812	R:R:I586	4.91	No	No	0	7	5
42	R:R:I586	R:R:I815	2.94	No	Yes	0	5	8
43	R:R:I586	R:R:L816	2.85	No	No	0	5	6
44	R:R:F587	R:R:V596	7.87	No	No	0	9	9
45	R:R:F587	R:R:I815	3.77	No	Yes	0	9	8
46	R:R:R589	R:R:W588	10	No	No	0	4	5
47	R:R:F591	R:R:W588	5.01	No	No	0	5	5
48	R:R:H590	R:R:T593	6.85	No	Yes	0	5	9
49	R:R:H590	R:R:I815	3.98	No	Yes	0	5	8
50	R:R:F591	R:R:Q592	4.68	No	No	0	5	4
51	R:R:F591	R:R:F605	4.29	No	No	0	5	6
52	R:R:P594	R:R:T593	5.25	No	Yes	0	8	9
53	R:R:T593	R:R:V596	3.17	Yes	No	0	9	9
54	R:R:N822	R:R:T593	8.77	No	Yes	0	9	9
55	R:R:P594	R:R:Y756	5.56	No	Yes	0	8	9
56	R:R:P594	R:R:P824	5.84	No	No	0	8	6
57	R:R:I595	R:R:Y756	3.63	Yes	Yes	4	7	9
58	R:R:I595	R:R:K811	4.36	Yes	No	4	7	9
59	R:R:I595	R:R:M814	2.92	Yes	No	4	7	8
60	R:R:I595	R:R:I815	4.42	Yes	Yes	0	7	8
61	R:R:N755	R:R:S598	7.45	No	No	0	8	9
62	R:R:F827	R:R:S598	3.96	No	No	0	7	9
63	R:R:A599	R:R:C604	3.61	No	No	0	9	9
64	R:R:G600	R:R:R651	3	No	Yes	0	9	9
65	R:R:G601	R:R:P602	4.06	No	No	0	8	6
66	R:R:P602	R:R:Y679	2.78	No	Yes	0	6	5
67	R:R:C647	R:R:M603	3.24	No	No	0	7	8
68	R:R:M603	R:R:Y679	4.79	No	Yes	10	8	5
69	R:R:M603	R:R:M682	7.22	No	No	10	8	7
70	R:R:C604	R:R:F605	8.38	No	No	0	9	6
71	R:R:L606	R:R:L610	8.3	No	Yes	0	6	8
72	R:R:L611	R:R:M607	2.83	No	Yes	11	9	8
73	R:R:C644	R:R:M607	6.48	No	Yes	11	7	8
74	R:R:C647	R:R:M607	3.24	No	Yes	0	7	8
75	R:R:I648	R:R:M607	4.37	Yes	Yes	0	7	8
76	R:R:F808	R:R:M607	8.71	No	Yes	0	9	8
77	R:R:F808	R:R:L608	6.09	No	No	0	9	9
78	R:R:C640	R:R:L610	3.17	No	Yes	0	7	8
79	R:R:I643	R:R:L610	8.56	No	Yes	0	7	8
80	R:R:C644	R:R:L610	3.17	No	Yes	0	7	8
81	R:R:C644	R:R:L611	4.76	No	No	11	7	9
82	R:R:I803	R:R:L611	4.28	No	No	0	8	9
83	R:R:M616	R:R:V613	3.04	No	No	0	6	6
84	R:R:A614	R:R:L800	3.15	No	No	0	6	8
85	R:R:L800	R:R:Y615	7.03	No	Yes	0	8	8
86	R:R:F637	R:R:V617	13.11	Yes	No	0	8	6
87	R:R:P619	R:R:V618	3.53	No	Yes	0	6	7
88	R:R:L793	R:R:V618	5.96	No	Yes	9	8	7
89	R:R:T629	R:R:V620	3.17	No	No	0	6	6
90	R:R:R633	R:R:Y621	21.61	Yes	No	0	8	8
91	R:R:L793	R:R:Y621	18.76	No	No	0	8	8
92	R:R:G623	R:R:V622	3.68	No	Yes	0	8	7
93	R:R:G623	R:R:P624	4.06	No	No	0	8	5
94	R:R:K626	R:R:P624	6.69	No	No	0	5	5
95	R:R:P625	R:R:R633	2.88	No	Yes	0	9	8
96	R:R:P625	R:R:V718	8.84	No	No	0	9	7
97	R:R:L631	R:R:V627	2.98	No	No	12	5	4
98	R:R:L702	R:R:V627	2.98	No	No	12	8	4
99	R:R:P704	R:R:V627	3.53	No	No	0	6	4
100	R:R:R633	R:R:T629	6.47	Yes	No	0	8	6
101	R:R:C630	R:R:P704	5.65	No	No	0	9	6
102	R:R:C630	R:R:C720	7.28	No	No	0	9	9
103	R:R:L631	R:R:L702	6.92	No	No	12	5	8
104	R:R:C632	R:R:F637	5.59	No	Yes	0	6	8
105	R:R:C720	R:R:R633	12.54	No	Yes	0	9	8
106	R:R:M697	R:R:Q634	12.23	No	No	0	7	8
107	R:R:C720	R:R:Q634	3.05	No	No	0	9	8
108	R:R:N721	R:R:Q634	2.64	Yes	No	0	6	8
109	R:R:F637	R:R:L636	3.65	Yes	No	0	8	6
110	R:R:I643	R:R:L639	4.28	No	No	0	7	7
111	R:R:F641	R:R:I645	8.79	No	Yes	3	8	7
112	R:R:F641	R:R:Y769	11.35	No	Yes	3	8	8
113	R:R:F641	R:R:L800	4.87	No	No	0	8	8
114	R:R:K689	R:R:T642	15.02	Yes	No	0	9	8
115	R:R:I645	R:R:L738	2.85	Yes	No	0	7	9
116	R:R:I645	R:R:Y769	9.67	Yes	Yes	3	7	8
117	R:R:I645	R:R:I803	2.94	Yes	No	0	7	8
118	R:R:C647	R:R:R651	2.79	No	Yes	0	7	9
119	R:R:I648	R:R:I762	2.94	Yes	Yes	0	7	9
120	R:R:I648	R:R:M766	7.29	Yes	No	0	7	9
121	R:R:I648	R:R:I803	2.94	Yes	No	0	7	8
122	R:R:M682	R:R:V650	7.61	No	No	0	7	8
123	R:R:E758	R:R:R651	10.47	Yes	Yes	4	9	9
124	R:R:R651	R:R:Y807	5.14	Yes	Yes	4	9	8
125	R:R:G742	R:R:S652	3.71	No	No	0	9	9
126	R:R:F745	R:R:S652	3.96	Yes	No	0	7	9
127	R:R:I762	R:R:S652	4.64	Yes	No	0	9	9
128	R:R:F653	R:R:F745	8.57	No	Yes	0	7	7
129	R:R:P678	R:R:Q654	3.16	Yes	No	0	8	8
130	R:R:I655	R:R:T754	4.56	No	No	0	9	7
131	R:R:E758	R:R:I655	5.47	Yes	No	0	9	9
132	R:R:C657	R:R:V656	5.12	No	No	0	6	7
133	R:R:F745	R:R:V656	3.93	Yes	No	0	7	7
134	R:R:C657	R:R:K660	6.47	No	No	0	6	6
135	R:R:F659	R:R:K660	16.13	No	No	0	9	6
136	R:R:M661	R:R:Y669	11.97	No	Yes	6	7	7
137	R:R:M661	R:R:W672	4.65	No	Yes	6	7	6
138	R:R:A662	R:R:Y669	2.67	No	Yes	0	7	7
139	R:R:F665	R:R:R664	18.17	No	No	0	5	7
140	R:R:W672	R:R:Y669	2.89	Yes	Yes	6	6	7
141	R:R:V673	R:R:Y669	10.09	No	Yes	0	6	7
142	R:R:W672	R:R:Y671	3.86	Yes	No	0	6	5
143	R:R:R674	R:R:Y671	4.12	No	No	0	7	5
144	R:R:G677	R:R:W672	8.44	No	Yes	6	8	6
145	R:R:P678	R:R:W672	12.16	Yes	Yes	6	8	6
146	R:R:R674	R:R:Y675	7.2	No	No	0	7	6
147	R:R:Q676	R:R:Y679	6.76	No	Yes	0	3	5
148	R:R:G677	R:R:P678	4.06	No	Yes	6	8	8
149	R:R:M682	R:R:Y679	4.79	No	Yes	10	7	5
150	R:R:I685	R:R:L738	4.28	No	No	0	5	9
151	R:R:L688	R:R:L734	2.77	No	Yes	0	6	8
152	R:R:K689	R:R:V693	3.04	Yes	No	0	9	7
153	R:R:K689	R:R:N731	6.99	Yes	No	3	9	7
154	R:R:K689	R:R:L734	4.23	Yes	Yes	0	9	8
155	R:R:D735	R:R:K689	6.91	No	Yes	3	8	9
156	R:R:M690	R:R:V694	6.09	No	No	0	4	4
157	R:R:M697	R:R:T700	3.01	No	No	0	7	6
158	R:R:L702	R:R:M697	2.83	No	No	0	8	7
159	R:R:P722	R:R:T705	5.25	No	No	0	6	3
160	R:R:T706	R:R:V718	4.76	No	No	0	3	7
161	R:R:I717	R:R:R707	7.52	No	No	0	6	6
162	R:R:D709	R:R:P710	6.44	Yes	No	0	3	4
163	R:R:D709	R:R:D711	10.65	Yes	No	0	3	5
164	R:R:D709	R:R:G785	5.03	Yes	No	0	3	7
165	R:R:D709	R:R:V786	7.3	Yes	No	0	3	8
166	R:R:D712	R:R:P713	6.44	No	No	0	4	4
167	R:R:D712	R:R:K714	4.15	No	No	0	4	4
168	R:R:I715	R:R:K714	2.91	Yes	No	0	4	4
169	R:R:I717	R:R:V786	6.14	No	No	0	6	8
170	R:R:S719	R:R:T789	3.2	No	No	0	5	7
171	R:R:N721	R:R:P722	3.26	Yes	No	0	6	6
172	R:R:N721	R:R:Y724	4.65	Yes	Yes	0	6	8
173	R:R:N721	R:R:S727	5.96	Yes	No	0	6	6
174	R:R:L728	R:R:N721	2.75	No	Yes	0	7	6
175	R:R:R725	R:R:Y724	18.52	No	Yes	0	2	8
176	R:R:M780	R:R:Y724	5.99	Yes	Yes	0	8	8
177	R:R:F730	R:R:N726	7.25	No	No	0	4	2
178	R:R:L728	R:R:M780	2.83	No	Yes	0	7	8
179	R:R:F730	R:R:L729	3.65	No	No	0	4	5
180	R:R:D735	R:R:N731	5.39	No	No	3	8	7
181	R:R:C777	R:R:T732	5.07	No	No	0	7	7
182	R:R:L734	R:R:L737	2.77	Yes	No	0	8	4
183	R:R:L734	R:R:L738	5.54	Yes	No	0	8	9
184	R:R:D735	R:R:Y769	6.9	No	Yes	3	8	8
185	R:R:S739	R:R:Y769	7.63	No	Yes	0	8	8
186	R:R:F770	R:R:S739	5.28	Yes	No	0	6	8
187	R:R:G742	R:R:V741	3.68	No	No	0	9	4
188	R:R:F745	R:R:V741	3.93	Yes	No	0	7	4
189	R:R:F743	R:R:T767	6.49	No	No	13	8	8
190	R:R:F743	S:S:F754	4.29	No	Yes	13	8	9
191	R:R:A746	R:R:I762	3.25	No	Yes	0	9	9
192	R:R:A746	R:R:T763	3.36	No	No	0	9	9
193	R:R:K750	R:R:Y747	9.55	No	No	0	9	8
194	R:R:Y747	S:S:F754	9.28	No	Yes	0	8	9
195	R:R:Y747	S:S:T770	3.75	No	No	0	8	9
196	R:R:G749	R:R:L752	3.42	No	No	0	9	8
197	R:R:K750	S:S:Q757	8.14	No	No	0	9	9
198	R:R:E751	S:S:Q757	3.82	No	No	0	7	9
199	R:R:L752	R:R:P753	3.28	No	No	0	8	9
200	R:R:N755	R:R:T754	5.85	No	No	0	8	7
201	R:R:E758	R:R:N755	14.46	Yes	No	0	9	8
202	R:R:M814	R:R:Y756	3.59	No	Yes	4	8	9
203	R:R:Y756	R:R:Y826	4.96	Yes	Yes	4	9	5
204	R:R:M830	R:R:Y756	9.58	No	Yes	4	4	9
205	R:R:K760	R:R:N757	2.8	No	No	0	9	9
206	R:R:E758	R:R:Y807	4.49	Yes	Yes	4	9	8
207	R:R:E758	R:R:K811	8.1	Yes	No	4	9	9
208	R:R:F761	R:R:P810	20.23	No	No	0	5	9
209	R:R:I762	R:R:Y807	6.04	Yes	Yes	0	9	8
210	R:R:T763	S:S:F754	3.89	No	Yes	0	9	9
211	R:R:L764	S:S:L755	6.92	No	No	0	9	8
212	R:R:T767	S:S:F754	10.38	No	Yes	13	8	9
213	R:R:F768	R:R:S772	2.64	No	No	0	7	9
214	R:R:A802	R:R:F768	5.55	No	No	0	7	7
215	R:R:S773	R:R:Y769	7.63	No	Yes	0	9	8
216	R:R:N799	R:R:Y769	6.98	No	Yes	3	9	8
217	R:R:F770	R:R:V774	5.24	Yes	No	0	6	6
218	R:R:S772	R:R:V795	3.23	No	Yes	3	9	8
219	R:R:N799	R:R:S772	8.94	No	No	3	9	9
220	R:R:L776	R:R:M780	8.48	No	Yes	3	9	8
221	R:R:D792	R:R:L776	4.07	No	No	3	9	9
222	R:R:L776	R:R:V795	7.45	No	Yes	3	9	8
223	R:R:T778	S:S:V781	4.76	No	No	0	8	6
224	R:R:T778	S:S:V784	4.76	No	No	0	8	7
225	R:R:F779	R:R:Y783	11.35	No	No	0	7	8
226	R:R:M780	R:R:V788	3.04	Yes	No	0	8	7
227	R:R:D792	R:R:M780	5.54	No	Yes	3	9	8
228	R:R:G785	R:R:Y783	7.24	No	No	0	7	8
229	R:R:L787	R:R:Y783	5.86	No	No	0	5	8
230	R:R:I790	R:R:L787	2.85	No	No	0	8	5
231	R:R:L794	R:R:L798	5.54	No	No	0	7	7
232	R:R:N799	R:R:V795	2.96	No	Yes	3	9	8
233	R:R:F808	R:R:Y807	9.28	No	Yes	0	9	8
234	R:R:K811	R:R:Y807	7.17	No	Yes	4	9	8
235	R:R:G809	R:R:P810	4.06	No	No	0	3	9
236	R:R:F817	R:R:L816	3.65	No	No	0	5	6
237	R:R:R821	R:R:Y818	30.87	No	No	0	5	6
238	R:R:E820	R:R:Y826	4.49	No	Yes	0	7	5
239	R:R:R821	R:R:Y826	11.32	No	Yes	0	5	5
240	R:R:P824	R:R:T823	3.5	No	No	0	6	7
241	R:R:S829	R:R:Y826	5.09	No	Yes	0	5	5
242	R:R:M830	R:R:Y826	4.79	No	Yes	4	4	5
243	R:R:I831	R:R:N828	4.25	No	No	0	7	6
244	S:S:R562	S:S:V723	3.92	No	No	0	8	7
245	S:S:E725	S:S:P564	3.14	Yes	No	0	7	4
246	S:S:K565	S:S:L719	2.82	No	Yes	8	5	4
247	S:S:E722	S:S:K565	20.25	No	No	8	5	5
248	S:S:K565	S:S:L724	4.23	No	Yes	8	5	6
249	S:S:F566	S:S:R632	8.55	Yes	No	5	7	4
250	S:S:F566	S:S:P633	4.33	Yes	No	5	7	9
251	S:S:E725	S:S:F566	3.5	Yes	Yes	5	7	7
252	S:S:L567	S:S:V574	2.98	No	No	0	9	7
253	S:S:L567	S:S:P796	4.93	No	No	0	9	8
254	S:S:A568	S:S:E571	4.53	No	No	0	7	7
255	S:S:P630	S:S:W569	5.4	No	No	0	7	5
256	S:S:G631	S:S:W569	4.22	No	No	0	8	5
257	S:S:G570	S:S:L575	3.42	No	No	0	4	5
258	S:S:E571	S:S:P572	3.14	No	No	0	7	4
259	S:S:E571	S:S:Y794	4.49	No	No	0	7	4
260	S:S:L578	S:S:V574	2.98	No	No	0	4	7
261	S:S:L577	S:S:M800	7.07	No	Yes	0	8	7
262	S:S:L577	S:S:L804	2.77	No	Yes	0	8	8
263	S:S:L580	S:S:V584	2.98	No	Yes	14	3	6
264	S:S:L580	S:S:L804	8.3	No	Yes	14	3	8
265	S:S:L581	S:S:L804	4.15	No	Yes	0	7	8
266	S:S:C623	S:S:V584	3.42	No	Yes	0	8	6
267	S:S:L804	S:S:V584	2.98	Yes	Yes	14	8	6
268	S:S:L585	S:S:L589	2.77	No	No	0	7	4
269	S:S:A588	S:S:L811	3.15	No	Yes	0	7	8
270	S:S:A591	S:S:L616	3.15	No	Yes	0	6	9
271	S:S:L592	S:S:L616	5.54	No	Yes	0	5	9
272	S:S:I617	S:S:L592	2.85	No	No	0	4	5
273	S:S:C819	S:S:L594	4.76	No	No	0	7	6
274	S:S:L594	S:S:L823	8.3	No	No	0	6	5
275	S:S:S595	S:S:V604	3.23	No	No	0	9	9
276	S:S:F612	S:S:S595	3.96	Yes	No	0	8	9
277	S:S:C613	S:S:S595	3.44	No	No	0	7	9
278	S:S:H597	S:S:H598	22.69	No	No	0	4	5
279	S:S:H598	S:S:S601	2.79	No	No	0	5	9
280	S:S:H598	S:S:L822	9	No	No	0	5	9
281	S:S:S610	S:S:W599	4.94	No	No	0	5	5
282	S:S:D600	S:S:Q605	3.92	No	No	0	4	7
283	S:S:S601	S:S:V604	3.23	No	No	0	9	9
284	S:S:N829	S:S:S601	8.94	No	No	0	9	9
285	S:S:N829	S:S:P602	4.89	No	No	0	9	9
286	S:S:P602	S:S:Q831	3.16	No	No	0	9	6
287	S:S:L603	S:S:L822	11.07	No	No	0	8	9
288	S:S:L603	S:S:N829	4.12	No	No	0	8	9
289	S:S:F834	S:S:L603	8.53	Yes	No	0	5	8
290	S:S:A606	S:S:F834	5.55	No	Yes	0	9	5
291	S:S:F612	S:S:S607	3.96	Yes	No	2	8	9
292	S:S:Q659	S:S:S607	2.89	Yes	No	2	9	9
293	S:S:K818	S:S:S607	7.65	Yes	No	2	9	9
294	S:S:G608	S:S:R682	4.5	No	No	0	9	7
295	S:S:S610	S:S:W687	4.94	No	Yes	0	5	4
296	S:S:A686	S:S:Q611	6.06	No	No	0	7	7
297	S:S:Q611	S:S:W687	9.86	No	Yes	0	7	4
298	S:S:F612	S:S:L616	3.65	Yes	Yes	2	8	9
299	S:S:F612	S:S:F814	5.36	Yes	Yes	2	8	9
300	S:S:F612	S:S:H815	10.18	Yes	Yes	2	8	9
301	S:S:F612	S:S:K818	4.96	Yes	Yes	2	8	9
302	S:S:C618	S:S:F614	6.98	No	No	0	8	5
303	S:S:F614	S:S:W687	6.01	No	Yes	0	5	4
304	S:S:G615	S:S:T655	3.64	No	No	0	8	8
305	S:S:H815	S:S:L616	11.57	Yes	Yes	2	9	9
306	S:S:C618	S:S:G651	3.92	No	No	0	8	7
307	S:S:C652	S:S:L619	4.76	No	No	0	7	9
308	S:S:L619	S:S:L811	2.77	No	Yes	0	9	8
309	S:S:L621	S:S:P648	3.28	No	No	0	5	7
310	S:S:A645	S:S:F622	2.77	No	Yes	0	8	6
311	S:S:F622	S:S:L649	17.05	Yes	No	0	6	8
312	S:S:F622	S:S:I803	11.3	Yes	No	0	6	9
313	S:S:A807	S:S:F622	2.77	No	Yes	0	8	6
314	S:S:A645	S:S:S625	3.42	No	No	0	8	8
315	S:S:M800	S:S:V626	4.56	Yes	No	0	7	7
316	S:S:I803	S:S:V626	3.07	No	No	0	9	7
317	S:S:L804	S:S:V626	4.47	Yes	No	0	8	7
318	S:S:F629	S:S:Q641	18.74	No	No	0	9	8
319	S:S:F629	S:S:Q799	7.03	No	No	0	9	8
320	S:S:F629	S:S:M800	4.98	No	Yes	0	9	7
321	S:S:M800	S:S:P630	8.39	Yes	No	0	7	7
322	S:S:P633	S:S:R632	4.32	No	No	5	9	4
323	S:S:E725	S:S:R632	10.47	Yes	No	5	7	4
324	S:S:E725	S:S:P633	4.72	Yes	No	5	7	9
325	S:S:S634	S:S:S637	6.52	No	No	0	5	6
326	S:S:C638	S:S:P710	3.77	No	No	0	9	8
327	S:S:C638	S:S:C727	7.28	No	No	0	9	9
328	S:S:L639	S:S:L705	4.15	No	No	0	6	7
329	S:S:C727	S:S:Q641	6.1	No	No	0	9	8
330	S:S:H646	S:S:Q642	6.18	Yes	Yes	1	5	8
331	S:S:Q642	S:S:Y704	6.76	Yes	Yes	1	8	7
332	S:S:L735	S:S:Q642	5.32	No	Yes	1	8	8
333	S:S:Q642	S:S:V738	4.3	Yes	Yes	1	8	7
334	S:S:Q642	S:S:Q799	6.4	Yes	No	0	8	8
335	S:S:C701	S:S:P643	3.77	No	No	0	7	6
336	S:S:P643	S:S:Y704	5.56	No	Yes	0	6	7
337	S:S:L705	S:S:P643	4.93	No	No	0	7	6
338	S:S:H646	S:S:V738	5.54	Yes	Yes	1	5	7
339	S:S:H646	S:S:H739	15.53	Yes	Yes	1	5	7
340	S:S:H646	S:S:N742	3.83	Yes	Yes	1	5	8
341	S:S:L647	S:S:P648	3.28	No	No	0	7	7
342	S:S:L647	S:S:T694	2.95	No	No	0	7	7
343	S:S:E697	S:S:L647	6.63	Yes	No	0	9	7
344	S:S:L649	S:S:N742	13.73	No	Yes	0	8	8
345	S:S:E697	S:S:T650	12.7	Yes	No	1	9	8
346	S:S:T650	S:S:T741	6.28	No	Yes	1	8	8
347	S:S:N742	S:S:T650	8.77	Yes	No	1	8	8
348	S:S:L653	S:S:L656	2.77	Yes	No	0	7	7
349	S:S:L653	S:S:N742	4.12	Yes	Yes	0	7	8
350	S:S:L653	S:S:L745	8.3	Yes	No	0	7	9
351	S:S:L653	S:S:M773	2.83	Yes	No	0	7	9
352	S:S:S654	S:S:V690	6.46	No	No	0	9	7
353	S:S:L745	S:S:S654	3	No	No	0	9	9
354	S:S:F657	S:S:L658	6.09	No	No	0	8	7
355	S:S:F657	S:S:L745	4.87	No	No	0	8	9
356	S:S:F657	S:S:L748	6.09	No	No	0	8	4
357	S:S:Q659	S:S:R765	4.67	Yes	Yes	0	9	9
358	S:S:F814	S:S:Q659	8.2	Yes	Yes	2	9	9
359	S:S:K818	S:S:Q659	4.07	Yes	Yes	2	9	9
360	S:S:A660	S:S:C749	3.61	No	No	0	9	9
361	S:S:E662	S:S:R682	12.79	No	No	0	8	7
362	S:S:E662	S:S:R765	9.3	No	Yes	0	8	9
363	S:S:R765	S:S:T663	11.64	Yes	No	0	9	9
364	S:S:E668	S:S:F664	7	No	No	0	6	6
365	S:S:L669	S:S:V665	2.98	No	Yes	0	7	7
366	S:S:L677	S:S:V665	7.45	No	Yes	0	5	7
367	S:S:E666	S:S:R765	3.49	No	Yes	0	8	9
368	S:S:S667	S:S:V756	3.23	No	No	0	9	8
369	S:S:L669	S:S:P670	4.93	No	No	16	7	8
370	S:S:L669	S:S:W673	3.42	No	No	16	7	6
371	S:S:P670	S:S:W673	4.05	No	No	16	8	6
372	S:S:S672	S:S:W673	3.71	No	No	0	6	6
373	S:S:L677	S:S:W676	7.97	No	No	0	5	5
374	S:S:W676	S:S:Y680	15.43	No	No	0	5	6
375	S:S:L677	S:S:L681	4.15	No	No	0	5	5
376	S:S:L684	S:S:L688	6.92	No	No	0	3	4
377	S:S:L700	S:S:V696	4.47	Yes	No	0	7	5
378	S:S:C701	S:S:E697	6.08	No	Yes	0	7	9
379	S:S:E697	S:S:T741	15.52	Yes	Yes	1	9	8
380	S:S:L700	S:S:L737	5.54	Yes	No	0	7	3
381	S:S:L700	S:S:T741	2.95	Yes	Yes	0	7	8
382	S:S:A707	S:S:W703	7.78	No	No	17	4	4
383	S:S:F708	S:S:W703	8.02	No	No	17	5	4
384	S:S:L737	S:S:W703	6.83	No	No	0	3	4
385	S:S:P710	S:S:Y704	6.95	No	Yes	0	8	7
386	S:S:S734	S:S:Y704	3.82	Yes	Yes	0	6	7
387	S:S:L737	S:S:Y704	4.69	No	Yes	0	3	7
388	S:S:V738	S:S:Y704	8.83	Yes	Yes	1	7	7
389	S:S:A707	S:S:F708	5.55	No	No	17	4	5
390	S:S:F708	S:S:S734	3.96	No	Yes	0	5	6
391	S:S:P709	S:S:R730	12.97	No	No	0	8	6
392	S:S:E711	S:S:R730	5.82	No	No	0	5	6
393	S:S:H726	S:S:V713	4.15	No	No	0	6	3
394	S:S:T714	S:S:W716	7.28	No	No	5	3	5
395	S:S:T714	S:S:V723	3.17	No	No	5	3	7
396	S:S:E725	S:S:T714	8.47	Yes	No	5	7	3
397	S:S:D715	S:S:V718	11.69	No	No	0	7	6
398	S:S:V723	S:S:W716	7.36	No	No	5	7	5
399	S:S:L724	S:S:V718	4.47	Yes	No	0	6	6
400	S:S:L719	S:S:P720	4.93	Yes	No	0	4	3
401	S:S:E722	S:S:L719	7.95	No	Yes	8	5	4
402	S:S:L719	S:S:L724	2.77	Yes	Yes	8	4	6
403	S:S:L724	S:S:V792	2.98	Yes	No	0	6	7
404	S:S:H726	S:S:H728	7.17	No	No	0	6	6
405	S:S:H726	S:S:V792	5.54	No	No	0	6	7
406	S:S:S734	S:S:V729	4.85	Yes	No	0	6	6
407	S:S:S731	S:S:V733	4.85	No	No	0	9	3
408	S:S:L735	S:S:V738	2.98	No	Yes	1	8	7
409	S:S:H739	S:S:L735	7.71	Yes	No	1	7	8
410	S:S:H739	S:S:V738	4.15	Yes	Yes	1	7	7
411	S:S:H739	S:S:W780	12.7	Yes	Yes	1	7	9
412	S:S:N742	S:S:T741	5.85	Yes	Yes	1	8	8
413	S:S:L748	S:S:M744	4.24	No	No	0	4	5
414	S:S:A746	S:S:Y776	2.67	No	Yes	1	8	8
415	S:S:A746	S:S:F777	4.16	No	No	1	8	7
416	S:S:F747	S:S:L751	8.53	No	No	0	3	5
417	S:S:C749	S:S:L769	4.76	No	No	0	9	9
418	S:S:C749	S:S:M773	8.1	No	No	0	9	9
419	S:S:F750	S:S:F754	23.58	No	Yes	0	8	9
420	S:S:F750	S:S:L774	3.65	No	No	0	8	8
421	S:S:A766	S:S:T753	3.36	No	No	0	9	9
422	S:S:L769	S:S:T753	7.37	No	No	0	9	9
423	S:S:T753	S:S:T770	4.71	No	No	0	9	9
424	S:S:F754	S:S:L755	6.09	Yes	No	0	9	8
425	S:S:Q757	S:S:S758	2.89	No	No	0	9	8
426	S:S:Q759	S:S:R762	9.35	No	No	0	8	7
427	S:S:R765	S:S:Y763	6.17	Yes	Yes	0	9	9
428	S:S:K818	S:S:Y763	5.97	Yes	Yes	2	9	9
429	S:S:F833	S:S:Y763	6.19	No	Yes	2	4	9
430	S:S:F834	S:S:Y763	9.28	Yes	Yes	2	5	9
431	S:S:N764	S:S:R767	7.23	No	No	0	9	9
432	S:S:F771	S:S:R767	9.62	No	No	0	9	9
433	S:S:F814	S:S:L769	4.87	Yes	No	0	9	9
434	S:S:A772	S:S:T813	3.36	No	No	0	9	6
435	S:S:F777	S:S:Y776	5.16	No	Yes	1	7	8
436	S:S:W780	S:S:Y776	10.61	Yes	Yes	1	9	8
437	S:S:C806	S:S:Y776	4.03	No	Yes	1	9	8
438	S:S:T779	S:S:V805	4.76	No	No	0	8	7
439	S:S:F783	S:S:W780	10.02	Yes	Yes	1	9	9
440	S:S:A802	S:S:W780	5.19	No	Yes	1	8	9
441	S:S:C806	S:S:W780	9.14	No	Yes	1	9	9
442	S:S:F783	S:S:L787	7.31	Yes	Yes	1	9	8
443	S:S:F783	S:S:V798	5.24	Yes	Yes	1	9	8
444	S:S:A802	S:S:F783	5.55	No	Yes	1	8	9
445	S:S:P785	S:S:V784	5.3	No	No	0	9	7
446	S:S:L786	S:S:V798	5.96	No	Yes	0	7	8
447	S:S:L787	S:S:Q795	3.99	Yes	No	0	8	6
448	S:S:L787	S:S:V798	4.47	Yes	Yes	1	8	8
449	S:S:G801	S:S:L804	3.42	No	Yes	0	7	8
450	S:S:L808	S:S:V812	2.98	No	No	0	6	2
451	S:S:H815	S:S:I810	2.65	Yes	No	0	9	8
452	S:S:H815	S:S:L811	3.86	Yes	Yes	2	9	8
453	S:S:L811	S:S:L816	2.77	Yes	No	2	8	3
454	S:S:F814	S:S:H815	11.31	Yes	Yes	2	9	9
455	S:S:F814	S:S:K818	8.69	Yes	Yes	2	9	9
456	S:S:W824	S:S:Y820	4.82	No	No	0	4	8
457	S:S:L828	S:S:V821	2.98	No	No	0	4	8
458	S:S:L823	S:S:W824	14.81	No	No	0	5	4
459	S:S:L825	S:S:L828	5.54	No	No	0	6	4
460	S:S:F833	S:S:L828	15.83	No	No	0	4	4
461	S:S:E832	S:S:Q831	3.82	No	No	15	6	6
462	S:S:L835	S:S:Q831	2.66	No	No	15	7	6
463	S:S:E832	S:S:L835	2.65	No	No	15	6	7
464	S:S:F833	S:S:F834	6.43	No	Yes	2	4	5
465	R:R:F684	R:R:V680	2.62	No	No	0	3	4
466	R:R:F770	R:R:V740	2.62	Yes	No	0	6	2
467	S:S:C613	S:S:W599	2.61	No	No	0	7	5
468	S:S:F771	S:S:T813	2.59	No	No	0	9	6
469	R:R:S784	R:R:Y724	2.54	No	Yes	0	6	8
470	S:S:V573	S:S:Y794	2.52	No	No	0	7	4
471	R:R:F745	R:R:M748	2.49	Yes	No	0	7	7
472	R:R:F761	R:R:M814	2.49	No	No	0	5	8
473	R:R:F770	R:R:L736	2.44	Yes	No	0	6	6
474	S:S:L787	S:S:W732	2.28	Yes	No	0	8	3
475	R:R:H590	R:R:R589	2.26	No	No	0	5	4
476	S:S:Q605	S:S:W599	2.19	No	No	0	7	5
477	S:S:G608	S:S:G609	2.11	No	No	0	9	8
478	R:R:F817	R:R:Y813	2.06	No	No	0	5	8
479	R:R:G806	R:R:P810	2.03	No	No	0	6	9
480	S:S:G761	S:S:P760	2.03	No	No	0	7	9
481	S:S:C618	S:S:G615	1.96	No	No	0	8	8
482	R:R:A649	R:R:G742	1.95	No	No	0	8	9
483	R:R:A699	R:R:G696	1.95	No	No	0	4	7
484	S:S:P709	S:S:P710	1.95	No	No	0	8	8
485	S:S:A775	S:S:G809	1.95	No	No	0	8	7
486	R:R:A564	R:R:P565	1.87	No	No	0	4	6
487	R:R:G749	R:R:V656	1.84	No	No	0	9	7
488	S:S:G593	S:S:V596	1.84	No	No	0	3	4
489	R:R:G701	R:R:T700	1.82	No	No	0	8	6
490	S:S:A591	S:S:C819	1.81	No	No	0	6	7
491	R:R:P704	R:R:S703	1.78	No	No	0	6	4
492	R:R:P722	R:R:S703	1.78	No	No	0	6	4
493	R:R:S781	S:S:P785	1.78	No	No	0	5	9
494	R:R:P678	R:R:V650	1.77	Yes	No	0	8	8
495	S:S:P630	S:S:V574	1.77	No	No	0	7	7
496	R:R:P713	R:R:T708	1.75	No	No	0	4	4
497	S:S:P720	S:S:T721	1.75	No	No	0	3	4
498	R:R:C632	R:R:V620	1.71	No	No	0	6	6
499	S:S:G620	S:S:L585	1.71	No	No	0	4	7
500	S:S:G586	S:S:L589	1.71	No	No	0	2	4
501	S:S:G593	S:S:L592	1.71	No	No	0	3	5
502	S:S:A636	S:S:S634	1.71	No	No	0	4	5
503	S:S:C638	S:S:V712	1.71	No	No	0	9	5
504	S:S:A693	S:S:S654	1.71	No	No	0	5	9
505	S:S:C678	S:S:V665	1.71	No	Yes	0	7	7
506	S:S:G809	S:S:L808	1.71	No	No	0	7	6
507	R:R:A635	R:R:V693	1.7	No	No	0	5	7
508	R:R:A782	S:S:V784	1.7	No	No	0	8	7
509	S:S:A797	S:S:V573	1.7	No	No	0	7	7
510	S:S:A674	S:S:V665	1.7	No	Yes	0	7	7
511	S:S:C806	S:S:T779	1.69	No	No	0	9	8
512	R:R:A825	R:R:T823	1.68	No	No	0	6	7
513	S:S:L816	S:S:P817	1.64	No	No	0	3	9
514	S:S:L825	S:S:P826	1.64	No	No	0	6	9
515	S:S:S731	S:S:S734	1.63	No	Yes	0	9	6
516	R:R:S744	R:R:V740	1.62	No	No	0	4	2
517	S:S:S635	S:S:V712	1.62	No	No	0	3	5
518	S:S:A640	S:S:M644	1.61	No	No	0	6	5
519	S:S:A772	S:S:M773	1.61	No	No	0	9	9
520	R:R:S628	R:R:T629	1.6	No	No	0	4	6
521	R:R:S646	R:R:T686	1.6	No	No	0	9	7
522	R:R:V693	R:R:V694	1.6	No	No	0	7	4
523	R:R:V774	S:S:V781	1.6	No	No	0	6	6
524	R:R:V791	R:R:V795	1.6	No	Yes	0	7	8
525	S:S:V790	S:S:V798	1.6	No	Yes	0	7	8
526	S:S:C623	S:S:L585	1.59	No	No	0	8	7
527	S:S:G736	S:S:H739	1.59	No	Yes	0	5	7
528	S:S:A797	S:S:L567	1.58	No	No	0	7	9
529	S:S:A797	S:S:L577	1.58	No	No	0	7	8
530	S:S:A640	S:S:L628	1.58	No	No	0	6	6
531	S:S:A699	S:S:L700	1.58	No	Yes	0	3	7
532	S:S:A793	S:S:L724	1.58	No	Yes	0	8	6
533	S:S:P760	S:S:Q759	1.58	No	No	0	9	8
534	R:R:T706	R:R:T716	1.57	No	No	0	3	7
535	S:S:A788	S:S:N789	1.56	No	No	0	6	8
536	R:R:I685	R:R:S646	1.55	No	No	0	5	9
537	R:R:I715	R:R:V557	1.54	Yes	No	0	4	5
538	R:R:I695	R:R:V691	1.54	No	No	0	4	3
539	R:R:I715	R:R:V786	1.54	Yes	No	0	4	8
540	R:R:M766	R:R:S765	1.53	No	No	0	9	9
541	S:S:M644	S:S:S625	1.53	No	No	0	5	8
542	R:R:M690	R:R:V691	1.52	No	No	0	4	3
543	S:S:I740	S:S:T741	1.52	No	Yes	0	5	8
544	S:S:F566	S:S:G631	1.51	Yes	No	0	7	8
545	R:R:L805	R:R:S579	1.5	No	No	0	2	4
546	R:R:L805	R:R:S804	1.5	No	No	0	2	8
547	S:S:G683	S:S:R682	1.5	No	No	0	6	7
548	S:S:G768	S:S:R767	1.5	No	No	0	5	9
549	S:S:L808	S:S:V584	1.49	No	Yes	0	6	6
550	S:S:L658	S:S:V689	1.49	No	No	0	7	6
551	R:R:L736	R:R:T732	1.47	No	No	0	6	7
552	S:S:D715	S:S:S717	1.47	No	No	0	7	3
553	R:R:D792	R:R:T796	1.45	No	No	0	9	8
554	R:R:F637	R:R:P638	1.44	Yes	No	0	8	5
555	R:R:F665	R:R:P666	1.44	No	No	0	5	7
556	S:S:P564	S:S:R563	1.44	No	No	0	4	2
557	S:S:Q641	S:S:S637	1.44	No	No	0	8	6
558	S:S:E666	S:S:S667	1.44	No	No	0	8	9
559	R:R:Q676	R:R:V680	1.43	No	No	0	3	4
560	S:S:E668	S:S:V756	1.43	No	No	0	6	8
561	R:R:K760	R:R:L764	1.41	No	No	0	9	9
562	S:S:E832	S:S:T830	1.41	No	No	0	6	8
563	R:R:A668	R:R:F665	1.39	No	No	0	5	5
564	R:R:P819	R:R:Y818	1.39	No	No	0	8	6
565	R:R:L581	R:R:L612	1.38	No	Yes	0	3	4
566	S:S:L578	S:S:L627	1.38	No	No	0	4	7
567	S:S:L580	S:S:L583	1.38	No	No	0	3	3
568	S:S:L581	S:S:L627	1.38	No	No	0	7	7
569	S:S:L587	S:S:L811	1.38	No	Yes	2	4	8
570	S:S:L587	S:S:L816	1.38	No	No	2	4	3
571	S:S:L621	S:S:L624	1.38	No	No	0	5	6
572	R:R:I715	R:R:Q555	1.37	Yes	No	0	4	3
573	R:R:N723	R:R:N726	1.36	No	No	0	5	2
574	R:R:A668	R:R:Y671	1.33	No	No	0	5	5
575	S:S:A793	S:S:Y794	1.33	No	No	0	8	4
576	R:R:R664	R:R:S663	1.32	No	No	0	7	5
577	R:R:F637	R:R:V613	1.31	Yes	No	0	8	6
578	R:R:F684	R:R:V687	1.31	No	No	0	3	5
579	R:R:F770	R:R:T771	1.3	Yes	No	0	6	8
580	R:R:F730	R:R:I692	1.26	No	No	0	4	6
581	S:S:F695	S:S:L692	1.22	No	No	0	4	4
582	S:S:F750	S:S:L751	1.22	No	No	0	8	5
583	R:R:Q592	R:R:R597	1.17	No	No	0	4	7
584	S:S:L688	S:S:W687	1.14	No	Yes	0	4	4

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:L559	3.754	5	7	8
2	R:R:T593	6.01	4	0	9
3	R:R:I595	3.8325	4	4	7
4	R:R:M607	5.126	5	11	8
5	R:R:L610	5.8	4	0	8
6	R:R:L612	3.705	4	0	4
7	R:R:Y615	7.0425	4	0	8
8	R:R:V618	4.0225	4	9	7
9	R:R:V622	6.905	4	7	7
10	R:R:R633	10.875	4	0	8
11	R:R:F637	5.02	5	0	8
12	R:R:I645	6.0625	4	3	7
13	R:R:I648	4.385	4	0	7
14	R:R:R651	5.35	4	4	9
15	R:R:Y669	6.905	4	6	7
16	R:R:W672	6.4	5	6	6
17	R:R:P678	5.2875	4	6	8
18	R:R:Y679	4.78	4	10	5
19	R:R:K689	7.238	5	3	9
20	R:R:D709	7.355	4	0	3
21	R:R:I715	1.84	4	0	4
22	R:R:N721	3.852	5	0	6
23	R:R:Y724	7.925	4	0	8
24	R:R:L734	3.8275	4	0	8
25	R:R:F745	4.576	5	0	7
26	R:R:Y756	5.464	5	4	9
27	R:R:E758	8.598	5	4	9
28	R:R:I762	4.2175	4	0	9
29	R:R:Y769	8.36	6	3	8
30	R:R:F770	3.376	5	0	6
31	R:R:M780	5.176	5	3	8
32	R:R:V795	3.81	4	3	8
33	R:R:Y807	6.424	5	4	8
34	R:R:I815	3.7775	4	0	8
35	R:R:Y826	6.13	5	4	5
36	S:S:F566	4.4725	4	5	7
37	S:S:V584	2.7175	4	14	6
38	S:S:F612	5.345	6	2	8
39	S:S:L616	5.9775	4	2	9
40	S:S:F622	8.4725	4	0	6
41	S:S:Q642	5.792	5	1	8
42	S:S:H646	7.77	4	1	5
43	S:S:L653	4.505	4	0	7
44	S:S:Q659	4.9575	4	2	9
45	S:S:V665	3.46	4	0	7
46	S:S:W687	5.4875	4	0	4
47	S:S:E697	10.2325	4	1	9
48	S:S:L700	3.635	4	0	7
49	S:S:Y704	6.10167	6	1	7
50	S:S:L719	4.6175	4	8	4
51	S:S:L724	3.206	5	8	6
52	S:S:E725	6.06	5	5	7
53	S:S:S734	3.565	4	0	6
54	S:S:V738	5.16	5	1	7
55	S:S:H739	8.336	5	1	7
56	S:S:T741	6.424	5	1	8
57	S:S:N742	7.26	5	1	8
58	S:S:F754	9.585	6	13	9
59	S:S:Y763	6.9025	4	2	9
60	S:S:R765	7.054	5	0	9
61	S:S:Y776	5.6175	4	1	8
62	S:S:W780	9.532	5	1	9
63	S:S:F783	7.03	4	1	9
64	S:S:L787	4.5125	4	1	8
65	S:S:V798	4.3175	4	1	8
66	S:S:M800	6.25	4	0	7
67	S:S:L804	4.34833	6	14	8
68	S:S:L811	2.786	5	2	8
69	S:S:F814	7.686	5	2	9
70	S:S:H815	7.914	5	2	9
71	S:S:K818	6.268	5	2	9
72	S:S:F834	7.4475	4	2	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:F558	R:R:P625	33.7624	4.33	No	No	0	7	9
2	R:R:F558	R:R:P624	31.1734	14.45	No	No	0	7	5
3	R:R:G623	R:R:P624	29.4401	4.06	No	No	0	8	5
4	R:R:G623	R:R:V622	28.5713	3.68	No	Yes	0	8	7
5	R:R:L559	R:R:V622	22.4123	4.47	Yes	Yes	7	8	7
6	R:R:I790	R:R:L559	18.9027	4.28	No	Yes	0	8	8
7	R:R:I790	R:R:L787	16.2416	2.85	No	No	0	8	5
8	R:R:L787	R:R:Y783	15.3516	5.86	No	No	0	5	8
9	R:R:G785	R:R:Y783	13.5674	7.24	No	No	0	7	8
10	R:R:D709	R:R:G785	12.673	5.03	Yes	No	0	3	7
11	R:R:P625	R:R:R633	38.0482	2.88	No	Yes	0	9	8
12	R:R:R633	R:R:Y621	11.7867	21.61	Yes	No	0	8	8
13	R:R:L793	R:R:Y621	10.8887	18.76	No	No	0	8	8
14	R:R:N799	R:R:Y769	75.7167	6.98	No	Yes	3	9	8
15	R:R:N799	R:R:V795	74.1722	2.96	No	Yes	3	9	8
16	R:R:L776	R:R:V795	73.9717	7.45	No	Yes	3	9	8
17	R:R:L776	R:R:M780	72.8288	8.48	No	Yes	3	9	8
18	R:R:M780	R:R:Y724	36.6714	5.99	Yes	Yes	0	8	8
19	R:R:N721	R:R:Y724	35.5737	4.65	Yes	Yes	0	6	8
20	R:R:N721	R:R:Q634	65.2529	2.64	Yes	No	0	6	8
21	R:R:C720	R:R:Q634	59.5436	3.05	No	No	0	9	8
22	R:R:C720	R:R:R633	58.1128	12.54	No	Yes	0	9	8
23	R:R:L728	R:R:M780	35.8098	2.83	No	Yes	0	7	8
24	R:R:L728	R:R:N721	35.4527	2.75	No	Yes	0	7	6
25	R:R:I645	R:R:I803	86.6185	2.94	Yes	No	0	7	8
26	R:R:I645	R:R:Y769	79.3829	9.67	Yes	Yes	3	7	8
27	R:R:I648	R:R:M607	16.1753	4.37	Yes	Yes	0	7	8
28	R:R:I648	R:R:I803	79.5404	2.94	Yes	No	0	7	8
29	R:R:I595	R:R:K811	19.2242	4.36	Yes	No	4	7	9
30	R:R:K811	R:R:Y807	18.6804	7.17	No	Yes	4	9	8
31	R:R:I762	R:R:Y807	33.1654	6.04	Yes	Yes	0	9	8
32	R:R:I648	R:R:I762	83.2832	2.94	Yes	Yes	0	7	9
33	R:R:C647	R:R:M607	17.9763	3.24	No	Yes	0	7	8
34	R:R:C647	R:R:M603	25.5071	3.24	No	No	0	7	8
35	R:R:M603	R:R:M682	17.6717	7.22	No	No	10	8	7
36	R:R:M682	R:R:V650	16.789	7.61	No	No	0	7	8
37	R:R:P678	R:R:V650	15.813	1.77	Yes	No	0	8	8
38	R:R:P678	R:R:W672	12.8669	12.16	Yes	Yes	6	8	6
39	R:R:T763	S:S:F754	99.9752	3.89	No	Yes	0	9	9
40	R:R:A746	R:R:T763	99.9898	3.36	No	No	0	9	9
41	R:R:A746	R:R:I762	100	3.25	No	Yes	0	9	9
42	R:R:Y747	S:S:F754	99.7536	9.28	No	Yes	0	8	9
43	R:R:Y747	S:S:T770	99.5926	3.75	No	No	0	8	9
44	S:S:T753	S:S:T770	99.5576	4.71	No	No	0	9	9
45	S:S:L769	S:S:T753	99.4803	7.37	No	No	0	9	9
46	S:S:C749	S:S:L769	89.4509	4.76	No	No	0	9	9
47	S:S:C749	S:S:M773	89.0967	8.1	No	No	0	9	9
48	S:S:L653	S:S:M773	87.808	2.83	Yes	No	0	7	9
49	S:S:L653	S:S:N742	85.6433	4.12	Yes	Yes	0	7	8
50	S:S:H646	S:S:N742	40.9747	3.83	Yes	Yes	1	5	8
51	S:S:H646	S:S:Q642	27.1573	6.18	Yes	Yes	1	5	8
52	S:S:Q642	S:S:Q799	23.4925	6.4	Yes	No	0	8	8
53	S:S:F629	S:S:Q799	23.1186	7.03	No	No	0	9	8
54	S:S:F629	S:S:M800	21.3037	4.98	No	Yes	0	9	7
55	S:S:M800	S:S:P630	14.9639	8.39	Yes	No	0	7	7
56	S:S:P630	S:S:W569	10.8537	5.4	No	No	0	7	5
57	S:S:L649	S:S:N742	36.4585	13.73	No	Yes	0	8	8
58	S:S:F622	S:S:L649	36.0883	17.05	Yes	No	0	6	8
59	S:S:F622	S:S:I803	33.5241	11.3	Yes	No	0	6	9
60	S:S:I803	S:S:V626	33.1778	3.07	No	No	0	9	7
61	S:S:M800	S:S:V626	17.7569	4.56	Yes	No	0	7	7
62	S:S:L577	S:S:M800	21.6973	7.07	No	Yes	0	8	7
63	S:S:A797	S:S:L577	28.9591	1.58	No	No	0	7	8
64	S:S:A797	S:S:V573	25.4663	1.7	No	No	0	7	7
65	S:S:V573	S:S:Y794	24.2068	2.52	No	No	0	7	4
66	S:S:A793	S:S:Y794	19.1542	1.33	No	No	0	8	4
67	S:S:A793	S:S:L724	17.8874	1.58	No	Yes	0	8	6
68	S:S:L804	S:S:V626	17.4938	4.47	Yes	No	0	8	7
69	S:S:L577	S:S:L804	10.861	2.77	No	Yes	0	8	8
70	S:S:F814	S:S:L769	43.5104	4.87	Yes	No	0	9	9
71	S:S:F612	S:S:F814	18.7453	5.36	Yes	Yes	2	8	9
72	S:S:F612	S:S:S595	13.5003	3.96	Yes	No	0	8	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 9OQ0

PDB Summary
PDB	9OQ0
Class	C
SubFamily	Sensory
Type	Taste1
SubType	TAS1R2; TAS1R3
Species	Homo Sapiens; Mus Musculus
Ligand	-
Other Ligand(s)	-
Protein Partners	-
PDB Resolution	3.67
Date	2025-08-27
D.O.I.	To be published

Net Summary
I_min	2.64
Number of Linked Nodes	520
Number of Links	584
Number of Hubs	72
Number of Links mediated by Hubs	272
Number of Communities	17
Number of Nodes involved in Communities	100
Number of Links involved in Communities	129

Path Summary
Number Of Nodes in MetaPath	73
Number Of Links MetaPath	72
Number of Shortest Paths	253787
Length Of Smallest Path	3
Average Path Length	23.0004
Length of Longest Path	57
Minimum Path Strength	1.36
Average Path Strength	5.50207
Maximum Path Strength	21.095
Minimum Path Correlation	0.7
Average Path Correlation	0.965315
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	4
Average % Of Corr. Nodes	46.5109
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	39.5603
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process	• sensory perception of sweet taste • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • sensory perception of umami taste • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • G protein-coupled receptor signaling pathway • cellular process • signal transduction • cell communication • membrane-bounded organelle • intracellular organelle • cellular anatomical structure • intracellular anatomical structure • Golgi apparatus • organelle • cytoplasm • intracellular membrane-bounded organelle • endomembrane system • cell periphery • plasma membrane • membrane • protein-containing complex • taste receptor complex
Gene Ontology	Cellular Component	• membrane-bounded organelle • intracellular organelle • cellular anatomical structure • intracellular anatomical structure • Golgi apparatus • organelle • cytoplasm • intracellular membrane-bounded organelle • endomembrane system • cell periphery • plasma membrane • membrane • protein-containing complex • taste receptor complex • sweet taste receptor complex • receptor complex • taste receptor activity • molecular transducer activity • transmembrane signaling receptor activity • signaling receptor activity • G protein-coupled receptor activity • sweet taste receptor activity • sensory perception of sweet taste • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • regulation of cytokinesis • regulation of biological process • regulation of cellular process • positive regulation of cell division • regulation of cell cycle process • biological regulation • positive regulation of biological process • cytokinesis • positive regulation of cell cycle • regulation of cell division • positive regulation of cytokinesis • positive regulation of cell cycle process • cellular process • cell division • cell cycle • regulation of cell cycle • positive regulation of cellular process • cell cycle process • response to stimulus • detection of chemical stimulus involved in sensory perception of sweet taste • detection of chemical stimulus involved in sensory perception of taste • detection of stimulus • response to chemical • detection of chemical stimulus • detection of stimulus involved in sensory perception • detection of chemical stimulus involved in sensory perception • cellular response to stimulus • signaling • G protein-coupled receptor signaling pathway • signal transduction • cell communication
SCOP2	Domain Identifier
SCOP2	Family Identifier
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q8TE23
Sequence	>9OQ0_Chain_R R Q L V F L E W H E A P T I A V A L L A A L G F L S T L A I L V I F W R H F Q T P I V R S A G G P M C F L M L T L L L V A Y M V V P V Y V G P P K V S T C L C R Q A L F P L C F T I C I S C I A V R S F Q I V C A F K M A S R F P R A Y S Y W V R Y Q G P Y V S M A F I T V L K M V I V V I G M L A T G L S P T T R T D P D D P K I T I V S C N P N Y R N S L L F N T S L D L L L S V V G F S F A Y M G K E L P T N Y N E A K F I T L S M T F Y F T S S V S L C T F M S A Y S G V L V T I V D L L V T V L N L L A I S L G Y F G P K C Y M I L F Y P E R N T P A Y F N S M I Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	S
Protein	Receptor
UniProt	Q925D8
Sequence	>9OQ0_Chain_S P R R P K F L A W G E P V V L S L L L L L C L V L G L A L A A L G L S V H H W D S P L V Q A S G G S Q F C F G L I C L G L F C L S V L L F P G R P S S A S C L A Q Q P M A H L P L T G C L S T L F L Q A A E T F V E S E L P L S W A N W L C S Y L R G L W A W L V V L L A T F V E A A L C A W Y L I A F P P E V V T D W S V L P T E V L E H C H V R S W V S L G L V H I T N A M L A F L C F L G T F L V Q S Q P G R Y N R A R G L T F A M L A Y F I T W V S F V P L L A N V Q V A Y Q P A V Q M G A I L V C A L G I L V T F H L P K C Y V L L W L P K L N T Q E F F L Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	9NOX	C	Sensory	Taste1	TAS1R2	Homo sapiens	-	-	chim(Gs-CtGt3)/β1/γ2	3	2025-04-09	doi.org/10.1016/j.cell.2025.04.021
	9NOX (No Gprot)	C	Sensory	Taste1	TAS1R2	Homo sapiens	-	-		3	2025-04-09	doi.org/10.1016/j.cell.2025.04.021
	9NOY	C	Sensory	Taste1	TAS1R2	Homo sapiens	-	-	-	3.7	2025-04-09	doi.org/10.1016/j.cell.2025.04.021
	9NOR	C	Sensory	Taste1	TAS1R2; TAS1R3	Homo sapiens	-	-	-	3.4	2025-04-09	doi.org/10.1016/j.cell.2025.04.021
	9NOS	C	Sensory	Taste1	TAS1R2; TAS1R3	Homo sapiens	-	-	-	3.5	2025-04-09	doi.org/10.1016/j.cell.2025.04.021
	9NOT	C	Sensory	Taste1	TAS1R2; TAS1R3	Homo sapiens	-	-	-	3.8	2025-04-09	doi.org/10.1016/j.cell.2025.04.021
	9O38	C	Sensory	Taste1	TAS1R2; TAS1R3	Homo sapiens	-	-	chim(Gs-CtGt3)/β1/γ2	3	2025-04-09	doi.org/10.1016/j.cell.2025.04.021
	9O38 (No Gprot)	C	Sensory	Taste1	TAS1R2; TAS1R3	Homo sapiens	-	-		3	2025-04-09	doi.org/10.1016/j.cell.2025.04.021
	9OQ0	C	Sensory	Taste1	TAS1R2; TAS1R3	Homo sapiens; mus musculus	-	-	-	3.67	2025-08-27	To be published
	9UT8	C	Sensory	Taste1	TAS1R2; TAS1R3	Homo sapiens	-	-	-	3.41	2025-07-16	doi.org/10.1038/s41586-025-09302-6
	9UTA	C	Sensory	Taste1	TAS1R2; TAS1R3	Homo sapiens	-	-	-	3.77	2025-07-16	doi.org/10.1038/s41586-025-09302-6
	9UTB	C	Sensory	Taste1	TAS1R2; TAS1R3	Homo sapiens	Sucralose	-	-	3.59	2025-07-16	doi.org/10.1038/s41586-025-09302-6

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