psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:A25	L:L:I64	3.25	No	No	0	3	8
2	L:L:G29	L:L:I102	5.29	No	No	0	6	5
3	L:L:L30	L:L:V52	4.47	No	No	0	8	7
4	L:L:L30	L:L:L68	11.07	No	No	0	8	8
5	L:L:I102	L:L:V32	3.07	No	No	0	5	6
6	L:L:R113	L:L:V32	6.54	No	No	0	7	6
7	L:L:E36	L:L:R113	23.26	No	No	0	5	7
8	L:L:E36	L:L:V115	11.41	No	No	12	5	3
9	L:L:E36	R:R:Y21	14.59	No	Yes	12	5	3
10	L:L:F37	L:L:L72	4.87	No	Yes	0	8	8
11	L:L:F37	R:R:Y21	9.28	No	Yes	0	8	3
12	L:L:H38	L:L:R78	10.16	No	No	0	9	2
13	L:L:H40	R:R:Y21	8.71	No	Yes	0	8	3
14	L:L:F70	L:L:V52	3.93	No	No	0	6	7
15	L:L:E53	L:L:F70	10.49	No	No	0	5	6
16	L:L:E69	L:L:S54	7.19	No	No	0	7	4
17	L:L:D57	L:L:I64	5.6	No	No	0	6	8
18	L:L:P59	L:L:T58	5.25	No	No	0	2	3
19	L:L:F60	L:L:T58	11.67	Yes	No	0	4	3
20	L:L:F65	L:L:T58	5.19	Yes	No	0	8	3
21	L:L:F60	L:L:P61	4.33	Yes	No	0	4	4
22	L:L:F60	L:L:Q139	12.88	Yes	No	0	4	5
23	L:L:I64	L:L:V66	4.61	No	No	0	8	9
24	L:L:C101	L:L:F65	4.19	Yes	Yes	0	9	8
25	L:L:F65	L:L:K103	3.72	Yes	No	0	8	9
26	L:L:F65	L:L:Q139	36.31	Yes	No	0	8	5
27	L:L:I102	L:L:V66	7.68	No	No	0	5	9
28	L:L:E69	L:L:R67	17.45	No	No	0	7	6
29	L:L:C101	L:L:R67	4.18	Yes	No	0	9	6
30	L:L:F70	L:L:K71	7.44	No	No	0	6	4
31	L:L:K71	L:L:K97	14.37	No	No	0	4	4
32	L:L:C98	L:L:L72	4.76	No	Yes	0	8	8
33	L:L:Q74	L:L:R78	3.5	No	No	0	9	2
34	L:L:C117	L:L:C98	7.28	No	No	0	9	8
35	L:L:H116	L:L:L99	6.43	No	No	0	8	7
36	L:L:A100	L:L:V115	3.39	No	No	0	8	3
37	L:L:C101	L:L:L114	6.35	Yes	Yes	13	9	7
38	L:L:C101	L:L:C135	7.28	Yes	No	13	9	9
39	L:L:G112	R:R:S26	3.71	No	No	0	5	4
40	L:L:R113	R:R:E25	8.14	No	No	0	7	7
41	L:L:C135	L:L:L114	6.35	No	Yes	13	9	7
42	L:L:L114	L:L:V138	4.47	Yes	No	0	7	8
43	L:L:L114	R:R:L24	8.3	Yes	No	0	7	4
44	L:L:V115	R:R:Y21	6.31	No	Yes	12	3	3
45	L:L:H116	R:R:D20	11.35	No	No	0	8	2
46	L:L:H116	R:R:Y22	7.62	No	No	0	8	5
47	L:L:Q134	R:R:Y22	7.89	No	No	0	6	5
48	L:L:Q134	R:R:L24	5.32	No	No	0	6	4
49	L:L:F150	L:L:R137	9.62	Yes	No	0	4	5
50	L:L:R137	R:R:Q192	5.84	No	No	0	5	4
51	L:L:F148	R:R:S26	10.57	No	No	0	1	4
52	L:L:F148	R:R:F181	7.5	No	Yes	0	1	4
53	L:L:Q153	L:L:Y149	4.51	Yes	Yes	3	6	5
54	L:L:F154	L:L:Y149	4.13	Yes	Yes	3	6	5
55	L:L:Y149	R:R:E269	8.98	Yes	No	3	5	4
56	L:L:Y149	R:R:I272	7.25	Yes	No	0	5	2
57	L:L:Y149	R:R:M282	11.97	Yes	Yes	3	5	4
58	L:L:F150	L:L:Q153	3.51	Yes	Yes	3	4	6
59	L:L:F150	R:R:V179	3.93	Yes	Yes	3	4	1
60	L:L:F150	R:R:F181	4.29	Yes	Yes	0	4	4
61	L:L:F150	R:R:Y188	15.47	Yes	Yes	3	4	3
62	L:L:P151	R:R:Y188	5.56	No	Yes	0	9	3
63	L:L:F154	L:L:Q153	12.88	Yes	Yes	3	6	6
64	L:L:Q153	R:R:L186	3.99	Yes	No	0	6	3
65	L:L:F154	R:R:M282	4.98	Yes	Yes	3	6	4
66	L:L:F154	R:R:Q283	4.68	Yes	No	0	6	3
67	L:L:F154	R:R:I286	7.54	Yes	Yes	3	6	4
68	L:L:F156	R:R:F86	4.29	Yes	Yes	6	9	7
69	L:L:F156	R:R:Y93	12.38	Yes	Yes	6	9	6
70	L:L:F156	R:R:F294	6.43	Yes	No	6	9	7
71	L:L:S157	R:R:S114	4.89	Yes	No	9	5	5
72	L:L:S157	R:R:Q118	5.78	Yes	Yes	0	5	5
73	L:L:S157	R:R:R176	3.95	Yes	Yes	9	5	4
74	R:R:S23	R:R:Y21	12.72	No	Yes	0	5	3
75	R:R:E180	R:R:S23	4.31	No	No	0	1	5
76	R:R:F181	R:R:L28	4.87	Yes	No	0	4	2
77	R:R:H279	R:R:L28	5.14	No	No	0	1	2
78	R:R:A284	R:R:V37	5.09	No	No	0	2	3
79	R:R:H38	R:R:L42	3.86	No	No	0	5	5
80	R:R:P287	R:R:S41	3.56	No	No	0	4	5
81	R:R:L42	R:R:Y45	3.52	No	Yes	0	5	8
82	R:R:A98	R:R:L42	4.73	No	No	0	4	5
83	R:R:G291	R:R:L44	3.42	No	No	0	4	5
84	R:R:Y45	R:R:Y93	8.94	Yes	Yes	6	8	6
85	R:R:I94	R:R:Y45	6.04	No	Yes	0	6	8
86	R:R:V97	R:R:Y45	3.79	No	Yes	0	5	8
87	R:R:T290	R:R:Y45	7.49	No	Yes	6	6	8
88	R:R:G291	R:R:Y45	5.79	No	Yes	0	4	8
89	R:R:L47	R:R:L51	5.54	No	No	0	4	5
90	R:R:F49	R:R:L90	8.53	No	No	0	7	7
91	R:R:F49	R:R:P91	5.78	No	No	0	7	9
92	R:R:C298	R:R:G52	3.92	No	No	0	7	8
93	R:R:I53	R:R:P54	3.39	No	No	0	6	4
94	R:R:F84	R:R:I53	3.77	No	No	0	7	6
95	R:R:D83	R:R:N56	6.73	Yes	Yes	14	9	9
96	R:R:N56	R:R:P301	6.52	Yes	No	14	9	9
97	R:R:F62	R:R:I58	3.77	Yes	No	0	7	6
98	R:R:T63	R:R:V59	3.17	Yes	No	0	7	8
99	R:R:A80	R:R:V59	3.39	No	No	0	8	8
100	R:R:V305	R:R:V59	3.21	No	No	0	6	8
101	R:R:A80	R:R:I60	3.25	No	No	0	8	7
102	R:R:F62	R:R:W61	11.02	Yes	No	0	7	4
103	R:R:F62	R:R:K66	4.96	Yes	No	0	7	5
104	R:R:F315	R:R:F62	8.57	No	Yes	0	5	7
105	R:R:G64	R:R:T63	3.64	Yes	Yes	8	3	7
106	R:R:T63	R:R:W67	3.64	Yes	Yes	8	7	6
107	R:R:T63	R:R:T73	3.14	Yes	No	0	7	8
108	R:R:L77	R:R:T63	4.42	No	Yes	8	6	7
109	R:R:G64	R:R:K69	3.49	Yes	No	0	3	7
110	R:R:G64	R:R:L77	3.42	Yes	No	8	3	6
111	R:R:K310	R:R:W67	3.48	No	Yes	8	6	6
112	R:R:F311	R:R:W67	5.01	Yes	Yes	0	8	6
113	R:R:R314	R:R:W67	12	No	Yes	8	6	6
114	R:R:W67	V:V:D68	6.7	Yes	No	0	6	8
115	R:R:W67	V:V:L69	7.97	Yes	No	0	6	8
116	R:R:K68	R:R:T70	4.5	No	Yes	0	7	7
117	R:R:K68	V:V:D68	9.68	No	No	0	7	8
118	R:R:K69	R:R:L74	4.23	No	No	0	7	6
119	R:R:T70	R:R:V71	3.17	Yes	Yes	0	7	6
120	R:R:T70	R:R:T73	4.71	Yes	No	0	7	8
121	R:R:T70	V:V:E67	7.06	Yes	No	0	7	7
122	R:R:V71	R:R:W75	7.36	Yes	Yes	4	6	7
123	R:R:R149	R:R:V71	10.46	Yes	Yes	4	7	6
124	R:R:S154	R:R:V71	8.08	No	Yes	4	7	6
125	R:R:T72	V:V:E67	4.23	No	No	0	7	7
126	R:R:I131	R:R:W75	3.52	No	Yes	0	8	7
127	R:R:D134	R:R:W75	8.93	No	Yes	0	8	7
128	R:R:S154	R:R:W75	3.71	No	Yes	4	7	7
129	R:R:I158	R:R:W75	4.7	Yes	Yes	4	7	7
130	R:R:F76	R:R:I131	5.02	No	No	0	8	8
131	R:R:F76	R:R:Y304	6.19	No	Yes	0	8	9
132	R:R:F76	R:R:V305	9.18	No	No	0	8	6
133	R:R:F127	R:R:N78	7.25	Yes	No	4	7	9
134	R:R:I158	R:R:N78	11.33	Yes	No	4	7	9
135	R:R:N78	R:R:W162	3.39	No	Yes	4	9	9
136	R:R:D83	R:R:L79	5.43	Yes	No	0	9	9
137	R:R:F127	R:R:L79	3.65	Yes	No	0	7	9
138	R:R:L128	R:R:L79	4.15	No	No	0	9	9
139	R:R:A82	R:R:N120	3.13	No	Yes	0	8	8
140	R:R:D83	R:R:S297	7.36	Yes	No	0	9	8
141	R:R:D83	R:R:P301	3.22	Yes	No	14	9	9
142	R:R:F84	R:R:L88	7.31	No	No	0	7	5
143	R:R:I85	R:R:N120	8.5	No	Yes	0	6	8
144	R:R:F86	R:R:N120	7.25	Yes	Yes	0	7	8
145	R:R:F294	R:R:F86	16.08	No	Yes	6	7	7
146	R:R:F89	R:R:N113	3.62	No	No	0	6	5
147	R:R:F89	R:R:T116	7.78	No	No	0	6	5
148	R:R:I94	R:R:L90	5.71	No	No	0	6	7
149	R:R:F294	R:R:L90	9.74	No	No	0	7	7
150	R:R:L92	R:R:W103	3.42	No	Yes	0	6	9
151	R:R:Y93	R:R:Y96	3.97	Yes	No	0	6	6
152	R:R:T290	R:R:Y93	7.49	No	Yes	6	6	6
153	R:R:F101	R:R:Y96	15.47	No	No	0	4	6
154	R:R:W103	R:R:Y96	11.58	Yes	No	0	9	6
155	R:R:F101	R:R:V97	3.93	No	No	0	4	5
156	R:R:H102	R:R:M99	5.25	No	No	0	5	4
157	R:R:H184	R:R:N100	6.38	No	No	0	3	3
158	R:R:H102	R:R:H184	3.58	No	No	0	5	3
159	R:R:H102	R:R:T185	4.11	No	No	0	5	4
160	R:R:F105	R:R:W103	25.05	No	Yes	0	7	9
161	R:R:C110	R:R:W103	5.22	No	Yes	9	9	9
162	R:R:C187	R:R:W103	5.22	No	Yes	9	9	9
163	R:R:F105	R:R:P104	7.22	No	No	0	7	3
164	R:R:F105	R:R:L109	6.09	No	No	0	7	5
165	R:R:I107	R:R:T178	6.08	No	No	0	4	5
166	R:R:C110	R:R:R176	5.57	No	Yes	9	9	4
167	R:R:C110	R:R:C187	7.28	No	No	9	9	9
168	R:R:R176	R:R:S114	10.54	Yes	No	9	4	5
169	R:R:F115	R:R:L173	3.65	No	No	0	6	4
170	R:R:N120	R:R:T116	4.39	Yes	No	0	8	5
171	R:R:G169	R:R:Q118	3.29	No	Yes	0	7	5
172	R:R:A172	R:R:Q118	4.55	No	Yes	0	4	5
173	R:R:K210	R:R:Q118	5.42	No	Yes	0	6	5
174	R:R:L119	R:R:W162	5.69	No	Yes	0	5	9
175	R:R:F122	R:R:M121	4.98	Yes	No	0	6	7
176	R:R:M121	R:R:W259	4.65	No	Yes	0	7	8
177	R:R:F122	R:R:F126	3.22	Yes	No	0	6	5
178	R:R:F122	R:R:I168	7.54	Yes	No	0	6	5
179	R:R:F122	R:R:K210	3.72	Yes	No	0	6	6
180	R:R:A123	R:R:W162	5.19	No	Yes	0	6	9
181	R:R:P218	R:R:V125	3.53	Yes	No	0	9	7
182	R:R:F126	R:R:I161	6.28	No	Yes	0	5	7
183	R:R:F126	R:R:L164	4.87	No	No	0	5	4
184	R:R:F127	R:R:I158	3.77	Yes	Yes	4	7	7
185	R:R:F127	R:R:I161	7.54	Yes	Yes	0	7	7
186	R:R:F127	R:R:W162	6.01	Yes	Yes	4	7	9
187	R:R:L128	R:R:N300	5.49	No	No	0	9	9
188	R:R:L128	R:R:Y304	8.21	No	Yes	0	9	9
189	R:R:P218	R:R:T129	3.5	Yes	No	0	9	7
190	R:R:T129	R:R:T221	4.71	No	No	0	7	6
191	R:R:I161	R:R:V130	3.07	Yes	No	0	7	6
192	R:R:M222	R:R:S132	4.6	No	No	0	8	9
193	R:R:C225	R:R:S132	3.44	No	No	0	6	9
194	R:R:S132	R:R:Y226	10.17	No	Yes	0	9	9
195	R:R:L133	R:R:T221	4.42	No	No	0	6	6
196	R:R:C225	R:R:L133	3.17	No	No	0	6	6
197	R:R:D134	R:R:R149	14.29	No	Yes	0	8	7
198	R:R:H135	R:R:L139	9	No	Yes	0	9	8
199	R:R:H135	R:R:H244	5.97	No	No	0	9	7
200	R:R:H135	V:V:V71	5.54	No	No	0	9	9
201	R:R:I140	R:R:Y136	13.3	No	No	0	7	7
202	R:R:C225	R:R:Y136	8.06	No	No	0	6	7
203	R:R:C228	R:R:Y136	6.72	No	No	0	4	7
204	R:R:H138	R:R:S145	6.97	No	No	4	8	6
205	R:R:H138	R:R:H146	5.97	No	No	4	8	5
206	R:R:H138	R:R:R149	6.77	No	Yes	4	8	7
207	R:R:L139	R:R:L229	6.92	Yes	No	0	8	7
208	R:R:L139	V:V:L74	4.15	Yes	Yes	0	8	7
209	R:R:L139	V:V:F245	3.65	Yes	No	0	8	6
210	R:R:H141	R:R:I140	7.95	No	No	0	6	7
211	R:R:I140	R:R:K232	4.36	No	No	0	7	5
212	R:R:P142	V:V:S246	3.56	No	No	0	8	7
213	R:R:P142	V:V:A248	5.61	No	No	0	8	6
214	R:R:H146	R:R:S145	5.58	No	No	4	5	6
215	R:R:H146	R:R:R149	3.39	No	Yes	4	5	7
216	R:R:H148	R:R:R147	10.16	No	No	0	3	5
217	R:R:N153	R:R:T150	5.85	No	No	0	4	6
218	R:R:K152	R:R:N153	4.2	No	No	0	5	4
219	R:R:I158	R:R:S154	3.1	Yes	No	4	7	7
220	R:R:I161	R:R:V157	3.07	Yes	No	0	7	6
221	R:R:G170	R:R:P171	4.06	No	No	0	4	8
222	R:R:L206	R:R:P171	3.28	No	No	0	5	8
223	R:R:F175	R:R:Y174	4.13	No	No	0	4	5
224	R:R:F175	R:R:F191	5.36	No	Yes	0	4	5
225	R:R:F175	R:R:R202	6.41	No	No	0	4	1
226	R:R:N189	R:R:R176	3.62	No	Yes	0	4	4
227	R:R:D177	R:R:V179	5.84	No	Yes	3	5	1
228	R:R:D177	R:R:Y188	11.49	No	Yes	3	5	3
229	R:R:D177	R:R:N190	14.81	No	No	3	5	3
230	R:R:T178	R:R:T185	3.14	No	No	0	5	4
231	R:R:C187	R:R:T178	3.38	No	No	0	9	5
232	R:R:V179	R:R:Y188	6.31	Yes	Yes	3	1	3
233	R:R:F181	R:R:L186	4.87	Yes	No	0	4	3
234	R:R:N190	R:R:Y188	10.47	No	Yes	3	3	3
235	R:R:F191	R:R:N189	12.08	Yes	No	0	5	4
236	R:R:K193	R:R:N190	12.59	No	No	0	2	3
237	R:R:F191	R:R:H203	13.58	Yes	No	0	5	4
238	R:R:F191	R:R:L206	6.09	Yes	No	0	5	5
239	R:R:Q192	R:R:T199	7.09	No	No	0	4	6
240	R:R:K193	R:R:R202	3.71	No	No	0	2	1
241	R:R:L198	R:R:R202	4.86	No	No	0	4	1
242	R:R:H204	R:R:L200	10.29	No	No	0	4	2
243	R:R:H273	R:R:L200	3.86	No	No	0	3	2
244	R:R:H203	R:R:L270	6.43	No	Yes	0	4	5
245	R:R:H204	R:R:L270	11.57	No	Yes	0	4	5
246	R:R:K210	R:R:L206	4.23	No	No	0	6	5
247	R:R:L270	R:R:T207	8.84	Yes	No	0	5	5
248	R:R:I267	R:R:W208	8.22	No	No	0	5	4
249	R:R:L270	R:R:W208	5.69	Yes	No	0	5	4
250	R:R:F211	R:R:Y215	8.25	No	Yes	15	6	8
251	R:R:F211	R:R:H263	5.66	No	No	15	6	8
252	R:R:F211	R:R:I267	7.54	No	No	0	6	5
253	R:R:I212	R:R:I213	5.89	No	No	0	5	4
254	R:R:G214	R:R:P218	4.06	No	Yes	0	5	9
255	R:R:L219	R:R:Y215	4.69	No	Yes	0	6	8
256	R:R:T260	R:R:Y215	11.24	No	Yes	0	5	8
257	R:R:H263	R:R:Y215	22.87	No	Yes	15	8	8
258	R:R:L216	R:R:L220	4.15	No	No	0	4	4
259	R:R:I248	R:R:Y226	8.46	No	Yes	0	7	9
260	R:R:Y226	V:V:L72	5.86	Yes	Yes	0	9	7
261	R:R:H244	R:R:L229	3.86	No	No	0	7	7
262	R:R:F245	R:R:I230	8.79	No	No	0	6	4
263	R:R:R236	R:R:V233	7.85	No	No	0	5	8
264	R:R:R236	V:V:F245	5.34	No	No	0	5	6
265	R:R:R236	V:V:L316	7.29	No	No	0	5	5
266	R:R:R243	R:R:S241	6.59	No	No	0	7	7
267	R:R:R243	V:V:S75	5.27	No	No	0	7	6
268	R:R:H244	R:R:I248	7.95	No	No	0	7	7
269	R:R:F245	R:R:L249	3.65	No	No	0	6	4
270	R:R:L303	R:R:V250	4.47	No	No	0	8	6
271	R:R:V251	R:R:Y304	3.79	No	Yes	0	7	9
272	R:R:F255	R:R:W259	9.02	No	Yes	0	9	8
273	R:R:C258	R:R:L292	4.76	No	No	0	7	7
274	R:R:C258	R:R:N296	3.15	No	No	0	7	9
275	R:R:H263	R:R:W259	7.41	No	Yes	0	8	8
276	R:R:A293	R:R:W259	6.48	No	Yes	0	8	8
277	R:R:N296	R:R:W259	6.78	No	Yes	0	9	8
278	R:R:P261	R:R:T260	3.5	No	No	0	9	5
279	R:R:P261	R:R:S289	3.56	No	No	0	9	7
280	R:R:L292	R:R:P261	3.28	No	No	0	7	9
281	R:R:S266	R:R:Y262	3.82	No	No	0	5	6
282	R:R:F265	R:R:G285	6.02	No	No	0	4	6
283	R:R:F265	R:R:I286	3.77	No	Yes	0	4	4
284	R:R:F265	R:R:S289	5.28	No	No	0	4	7
285	R:R:T271	R:R:W268	9.7	No	No	0	4	4
286	R:R:W268	R:R:Y277	17.36	No	Yes	0	4	1
287	R:R:E269	R:R:M282	10.83	No	Yes	3	4	4
288	R:R:E269	R:R:I286	5.47	No	Yes	3	4	4
289	R:R:I272	R:R:Y277	14.51	No	Yes	0	2	1
290	R:R:N275	R:R:S276	4.47	No	No	0	3	3
291	R:R:V281	R:R:Y277	5.05	No	Yes	0	1	1
292	R:R:M282	R:R:Y277	10.78	Yes	Yes	0	4	1
293	R:R:H280	R:R:S278	4.18	No	No	0	3	2
294	R:R:H280	R:R:Q283	3.71	No	No	0	3	3
295	R:R:I286	R:R:M282	4.37	Yes	Yes	3	4	4
296	R:R:I286	R:R:P287	3.39	Yes	No	0	4	4
297	R:R:N296	R:R:N300	12.26	No	No	0	9	9
298	R:R:L306	R:R:P301	3.28	No	No	0	6	9
299	R:R:I302	R:R:L306	5.71	No	No	0	6	6
300	R:R:Y304	V:V:L72	4.69	Yes	Yes	0	9	7
301	R:R:V305	V:V:L69	4.47	No	No	0	6	8
302	R:R:F311	R:R:L306	6.09	Yes	No	0	8	6
303	R:R:F311	R:R:S308	3.96	Yes	No	0	8	8
304	R:R:K310	R:R:R314	7.43	No	No	8	6	6
305	R:R:F311	R:R:F315	6.43	Yes	No	0	8	5
306	R:R:?1357	R:R:C1358	4.05	Yes	No	0	6	5
307	R:R:?1357	V:V:K12	8.39	Yes	No	0	6	9
308	R:R:?1357	V:V:R166	7.23	Yes	No	0	6	5
309	R:R:?1359	R:R:C1358	3.91	No	No	0	4	5
310	R:R:C1358	V:V:P15	3.77	No	No	0	5	6
311	R:R:?1359	R:R:?1360	19.6	No	No	0	4	6
312	R:R:?1360	V:V:K12	17.37	No	No	0	6	9
313	R:R:?1360	V:V:R26	13.97	No	Yes	0	6	9
314	R:R:?1362	R:R:A1361	4.02	Yes	No	2	4	7
315	R:R:A1361	V:V:K11	4.82	No	Yes	2	7	9
316	R:R:?1362	R:R:?1363	17.02	Yes	Yes	2	4	7
317	R:R:?1362	V:V:R8	18.6	Yes	No	2	4	5
318	R:R:?1362	V:V:K11	3.6	Yes	Yes	2	4	9
319	R:R:?1363	R:R:?1364	20.02	Yes	Yes	2	7	5
320	R:R:?1363	V:V:R8	15.5	Yes	No	2	7	5
321	R:R:?1363	V:V:V9	6.33	Yes	No	0	7	8
322	R:R:?1363	V:V:K11	11.99	Yes	Yes	2	7	9
323	R:R:?1363	V:V:Y22	8.97	Yes	Yes	2	7	9
324	R:R:?1363	V:V:K108	6	Yes	No	2	7	9
325	R:R:?1364	R:R:L1365	8.24	Yes	Yes	2	5	5
326	R:R:?1364	V:V:R8	11.36	Yes	No	2	5	5
327	R:R:?1364	V:V:K108	6	Yes	No	2	5	9
328	R:R:L1365	V:V:T7	11.79	Yes	No	2	5	4
329	R:R:L1365	V:V:V9	4.47	Yes	No	0	5	8
330	R:R:L1365	V:V:R104	10.93	Yes	Yes	2	5	6
331	V:V:R104	V:V:T7	6.47	Yes	No	2	6	4
332	V:V:E352	V:V:F10	9.33	Yes	No	1	1	6
333	V:V:F10	V:V:H355	14.71	No	Yes	1	6	1
334	V:V:K11	V:V:Y22	10.75	Yes	Yes	2	9	9
335	V:V:K12	V:V:L167	8.46	No	No	0	9	8
336	V:V:S13	V:V:T20	4.8	No	No	0	5	7
337	V:V:P15	V:V:S14	3.56	No	Yes	0	6	7
338	V:V:K18	V:V:S14	10.71	Yes	Yes	0	5	7
339	V:V:S14	V:V:V165	3.23	Yes	No	0	7	8
340	V:V:K18	V:V:Y48	19.11	Yes	Yes	16	5	5
341	V:V:K18	V:V:N163	13.99	Yes	No	16	5	7
342	V:V:T20	V:V:Y22	4.99	No	Yes	0	7	9
343	V:V:V21	V:V:V42	3.21	No	No	0	6	5
344	V:V:V165	V:V:V21	3.21	No	No	0	8	6
345	V:V:L43	V:V:Y22	3.52	No	Yes	2	5	9
346	V:V:L105	V:V:Y22	4.69	No	Yes	0	9	9
347	V:V:L109	V:V:Y22	11.72	Yes	Yes	2	7	9
348	V:V:G24	V:V:L101	3.42	No	No	0	8	5
349	V:V:F28	V:V:K25	7.44	Yes	No	1	8	8
350	V:V:D36	V:V:K25	6.91	No	No	1	7	8
351	V:V:E352	V:V:K25	4.05	Yes	No	1	1	8
352	V:V:L167	V:V:R26	3.64	No	Yes	0	8	9
353	V:V:R26	V:V:V168	3.92	Yes	No	0	9	5
354	V:V:H355	V:V:R26	10.16	Yes	Yes	0	1	9
355	V:V:D27	V:V:R170	15.48	No	Yes	0	9	9
356	V:V:D27	V:V:P353	8.05	No	No	0	9	1
357	V:V:D36	V:V:F28	3.58	No	Yes	1	7	8
358	V:V:F28	V:V:V38	14.42	Yes	No	1	8	7
359	V:V:F28	V:V:I169	7.54	Yes	No	1	8	8
360	V:V:H31	V:V:V29	5.54	No	No	0	6	7
361	V:V:F174	V:V:V29	6.55	No	No	0	5	7
362	V:V:D30	V:V:L32	6.79	No	No	0	9	5
363	V:V:D30	V:V:Q173	10.44	No	No	0	9	9
364	V:V:H31	V:V:K34	7.86	No	No	0	6	3
365	V:V:D36	V:V:H31	6.3	No	No	0	7	6
366	V:V:I306	V:V:L32	4.28	No	No	0	5	5
367	V:V:I120	V:V:V35	10.75	Yes	No	0	5	7
368	V:V:F117	V:V:P37	5.78	No	No	0	4	6
369	V:V:I120	V:V:V38	3.07	Yes	No	0	5	7
370	V:V:I169	V:V:V38	3.07	No	No	1	8	7
371	V:V:D39	V:V:G40	3.35	No	No	0	7	8
372	V:V:D39	V:V:T99	5.78	No	No	0	7	8
373	V:V:D39	V:V:L101	9.5	No	No	0	7	5
374	V:V:F116	V:V:G40	6.02	Yes	No	0	9	8
375	V:V:L105	V:V:V41	7.45	No	No	0	9	7
376	V:V:P115	V:V:V41	3.53	No	No	0	6	7
377	V:V:F116	V:V:V42	3.93	Yes	No	0	9	5
378	V:V:L109	V:V:L43	11.07	Yes	No	2	7	5
379	V:V:D45	V:V:P46	11.27	No	No	0	8	5
380	V:V:D45	V:V:Y48	3.45	No	Yes	0	8	5
381	V:V:H112	V:V:P46	4.58	No	No	0	7	5
382	V:V:R52	V:V:Y48	6.17	No	Yes	0	6	5
383	V:V:V151	V:V:Y48	5.05	No	Yes	0	6	5
384	V:V:N163	V:V:Y48	4.65	No	Yes	16	7	5
385	V:V:F55	V:V:K53	7.44	Yes	No	10	3	5
386	V:V:K53	V:V:Q86	5.42	No	No	10	5	8
387	V:V:V151	V:V:V54	4.81	No	No	0	6	6
388	V:V:F55	V:V:Q86	7.03	Yes	No	10	3	8
389	V:V:F150	V:V:F55	5.36	Yes	Yes	10	5	3
390	V:V:F55	V:V:S154	3.96	Yes	No	0	3	4
391	V:V:F116	V:V:V56	10.49	Yes	No	11	9	7
392	V:V:F118	V:V:V56	3.93	Yes	No	11	8	7
393	V:V:T57	V:V:T84	4.71	No	No	0	6	4
394	V:V:F150	V:V:T57	5.19	Yes	No	0	5	6
395	V:V:F118	V:V:L58	10.96	Yes	No	0	8	7
396	V:V:I147	V:V:L58	4.28	No	No	0	6	7
397	V:V:D79	V:V:T59	7.23	No	No	0	8	7
398	V:V:I82	V:V:T59	6.08	No	No	0	4	7
399	V:V:L80	V:V:V60	5.96	No	No	0	7	7
400	V:V:F145	V:V:V60	7.87	No	No	0	7	7
401	V:V:A61	V:V:R77	4.15	No	No	0	8	8
402	V:V:F62	V:V:L80	4.87	Yes	No	0	9	7
403	V:V:F62	V:V:V143	5.24	Yes	No	0	9	9
404	V:V:F62	V:V:I242	6.28	Yes	Yes	17	9	7
405	V:V:F62	V:V:L244	8.53	Yes	No	0	9	7
406	V:V:F62	V:V:I318	5.02	Yes	Yes	17	9	8
407	V:V:L141	V:V:R63	3.64	No	No	0	7	8
408	V:V:L74	V:V:Y64	5.86	Yes	No	0	7	8
409	V:V:K78	V:V:Y64	14.33	No	No	0	9	8
410	V:V:L244	V:V:Y64	5.86	No	No	0	7	8
411	V:V:E67	V:V:F76	5.83	No	No	0	7	9
412	V:V:D70	V:V:G73	5.03	No	No	0	9	9
413	V:V:D70	V:V:L74	5.43	No	Yes	0	9	7
414	V:V:L72	V:V:V71	4.47	Yes	No	0	7	9
415	V:V:F76	V:V:L74	6.09	No	Yes	0	9	7
416	V:V:D79	V:V:R77	10.72	No	No	0	8	8
417	V:V:L80	V:V:P125	3.28	No	Yes	0	7	9
418	V:V:F81	V:V:P121	15.89	No	No	18	5	7
419	V:V:F81	V:V:L124	4.87	No	No	18	5	6
420	V:V:F116	V:V:Y85	3.09	Yes	Yes	11	9	3
421	V:V:F118	V:V:Y85	3.09	Yes	Yes	11	8	3
422	V:V:P98	V:V:Q102	4.74	No	No	0	4	8
423	V:V:D103	V:V:P98	4.83	No	No	0	5	4
424	V:V:Q102	V:V:T99	5.67	No	No	0	8	8
425	V:V:P115	V:V:Q102	9.47	No	No	0	6	8
426	V:V:L106	V:V:P115	8.21	No	No	0	3	6
427	V:V:A113	V:V:L109	3.15	No	Yes	0	8	7
428	V:V:F116	V:V:F118	3.22	Yes	Yes	11	9	8
429	V:V:I120	V:V:P121	3.39	Yes	No	0	5	7
430	V:V:I120	V:V:K171	4.36	Yes	No	0	5	9
431	V:V:L124	V:V:P121	4.93	No	No	18	6	7
432	V:V:L124	V:V:P125	4.93	No	Yes	0	6	9
433	V:V:P125	V:V:V143	8.84	Yes	No	0	9	9
434	V:V:G317	V:V:P125	4.06	No	Yes	0	9	9
435	V:V:Q173	V:V:S126	5.78	No	No	0	9	7
436	V:V:R170	V:V:S127	6.59	Yes	No	0	9	9
437	V:V:G292	V:V:S127	3.71	No	No	0	9	9
438	V:V:V128	V:V:V143	3.21	No	No	0	9	9
439	V:V:I318	V:V:V128	7.68	Yes	No	0	8	9
440	V:V:G292	V:V:T129	3.64	No	No	0	9	6
441	V:V:K293	V:V:T129	7.51	No	No	0	6	6
442	V:V:G287	V:V:L130	5.13	No	No	0	9	8
443	V:V:L288	V:V:Q131	7.99	No	No	1	6	9
444	V:V:L290	V:V:Q131	7.99	Yes	No	1	9	9
445	V:V:F145	V:V:K171	7.44	No	No	0	7	9
446	V:V:E146	V:V:R148	8.14	No	No	0	6	7
447	V:V:E146	V:V:R166	15.12	No	No	0	6	5
448	V:V:I147	V:V:I169	4.42	No	No	0	6	8
449	V:V:F150	V:V:R148	12.83	Yes	No	10	5	7
450	V:V:R148	V:V:S164	9.22	No	No	10	7	7
451	V:V:A149	V:V:V165	3.39	No	No	0	6	8
452	V:V:F150	V:V:S164	5.28	Yes	No	10	5	7
453	V:V:N163	V:V:R162	6.03	No	No	0	7	7
454	V:V:L294	V:V:V168	7.45	Yes	No	0	7	5
455	V:V:L294	V:V:R170	10.93	Yes	Yes	1	7	9
456	V:V:E297	V:V:R170	3.49	Yes	Yes	1	5	9
457	V:V:F174	V:V:P349	13	No	No	0	5	8
458	V:V:A175	V:V:L208	4.73	No	No	0	9	4
459	V:V:L208	V:V:P176	3.28	No	No	0	4	9
460	V:V:I306	V:V:P176	3.39	No	No	0	5	9
461	V:V:E177	V:V:K178	6.75	No	No	0	3	2
462	V:V:G180	V:V:P181	4.06	No	No	19	4	4
463	V:V:E207	V:V:G180	3.27	No	No	19	7	4
464	V:V:E207	V:V:P181	9.43	No	No	19	7	4
465	V:V:P183	V:V:Q182	3.16	No	No	0	9	6
466	V:V:L204	V:V:P183	6.57	Yes	No	0	7	9
467	V:V:E207	V:V:P183	3.14	No	No	0	7	9
468	V:V:S184	V:V:S203	6.52	No	No	0	4	6
469	V:V:E186	V:V:H199	9.85	No	Yes	0	5	5
470	V:V:T187	V:V:V338	4.76	No	Yes	0	7	7
471	V:V:H199	V:V:T188	8.21	Yes	No	0	5	6
472	V:V:R189	V:V:V336	9.15	No	No	0	8	7
473	V:V:K227	V:V:L198	5.64	No	No	0	8	6
474	V:V:L198	V:V:L328	5.54	No	No	0	6	6
475	V:V:E201	V:V:H199	9.85	No	Yes	0	7	5
476	V:V:H199	V:V:T222	5.48	Yes	No	0	5	5
477	V:V:L200	V:V:L328	12.46	No	No	0	5	6
478	V:V:L200	V:V:V338	5.96	No	Yes	0	5	7
479	V:V:A202	V:V:L340	4.73	No	Yes	0	7	6
480	V:V:L204	V:V:Y209	4.69	Yes	Yes	0	7	7
481	V:V:L204	V:V:V217	5.96	Yes	No	0	7	6
482	V:V:L204	V:V:L340	4.15	Yes	Yes	0	7	6
483	V:V:D205	V:V:K206	15.21	No	No	5	5	8
484	V:V:D205	V:V:Y209	9.2	No	Yes	5	5	7
485	V:V:K206	V:V:Y209	13.14	No	Yes	5	8	7
486	V:V:E213	V:V:K206	8.1	No	No	5	7	8
487	V:V:E213	V:V:Y209	5.61	No	Yes	5	7	7
488	V:V:L215	V:V:Y209	10.55	No	Yes	5	7	7
489	V:V:F342	V:V:Y209	4.13	No	Yes	5	6	7
490	V:V:P347	V:V:Y210	22.25	No	No	0	8	7
491	V:V:H211	V:V:N300	11.48	Yes	No	20	9	9
492	V:V:H211	V:V:S303	5.58	Yes	No	0	9	9
493	V:V:H211	V:V:L344	10.29	Yes	No	0	9	8
494	V:V:H211	V:V:H346	22.69	Yes	No	20	9	7
495	V:V:E213	V:V:P214	3.14	No	No	0	7	4
496	V:V:F342	V:V:L215	7.31	No	No	5	6	7
497	V:V:N216	V:V:T274	5.85	No	No	0	4	4
498	V:V:H220	V:V:N218	11.48	No	No	0	4	5
499	V:V:V219	V:V:V326	3.21	No	No	0	6	7
500	V:V:H220	V:V:S270	6.97	No	No	0	4	5
501	V:V:V221	V:V:V263	3.21	No	Yes	0	6	6
502	V:V:N224	V:V:T222	5.85	No	No	0	6	5
503	V:V:N223	V:V:V263	5.91	No	Yes	0	9	6
504	V:V:N223	V:V:P265	6.52	No	No	0	9	5
505	V:V:S225	V:V:T226	4.8	No	No	0	8	5
506	V:V:Q262	V:V:T228	5.67	No	No	0	6	5
507	V:V:P265	V:V:T228	5.25	No	No	0	5	5
508	V:V:V229	V:V:V263	3.21	No	Yes	0	8	6
509	V:V:I232	V:V:Q259	10.98	No	Yes	7	6	5
510	V:V:D261	V:V:I232	5.6	Yes	No	7	7	6
511	V:V:I232	V:V:Y273	8.46	No	Yes	7	6	4
512	V:V:E258	V:V:K233	6.75	No	No	0	6	6
513	V:V:V234	V:V:V326	4.81	No	No	0	5	7
514	V:V:Q256	V:V:S235	5.78	No	No	0	1	5
515	V:V:I275	V:V:V236	6.14	No	No	0	5	7
516	V:V:V236	V:V:V324	4.81	No	No	0	7	7
517	V:V:R237	V:V:Y239	10.29	Yes	Yes	0	6	3
518	V:V:K325	V:V:R237	9.9	No	Yes	0	7	6
519	V:V:A289	V:V:Q238	4.55	No	No	5	9	8
520	V:V:Q238	V:V:V320	4.3	No	Yes	5	8	9
521	V:V:Q238	V:V:Y322	18.04	No	Yes	5	8	9
522	V:V:Q249	V:V:Y239	5.64	No	Yes	0	6	3
523	V:V:R323	V:V:Y239	14.4	No	Yes	21	5	3
524	V:V:E339	V:V:Y239	4.49	No	Yes	21	7	3
525	V:V:A240	V:V:Y250	5.34	No	No	0	6	5
526	V:V:D241	V:V:Q249	10.44	No	No	0	6	6
527	V:V:D241	V:V:L319	4.07	No	No	0	6	5
528	V:V:I242	V:V:Y250	9.67	Yes	No	0	7	5
529	V:V:I242	V:V:I318	5.89	Yes	Yes	17	7	8
530	V:V:F245	V:V:L244	4.87	No	No	0	6	7
531	V:V:P253	V:V:V252	3.53	No	No	0	3	5
532	V:V:P253	V:V:Q256	3.16	No	No	0	3	1
533	V:V:P277	V:V:V254	3.53	No	No	0	9	9
534	V:V:N282	V:V:V254	7.39	No	No	0	9	9
535	V:V:A255	V:V:I275	3.25	No	No	0	7	5
536	V:V:D261	V:V:Q259	13.05	Yes	Yes	7	7	5
537	V:V:K271	V:V:Q259	9.49	No	Yes	7	8	5
538	V:V:Q259	V:V:Y273	16.91	Yes	Yes	7	5	4
539	V:V:D261	V:V:V263	4.38	Yes	Yes	7	7	6
540	V:V:D261	V:V:F269	17.91	Yes	No	7	7	4
541	V:V:S267	V:V:V263	3.23	No	Yes	0	6	6
542	V:V:F269	V:V:V263	6.55	No	Yes	7	4	6
543	V:V:P265	V:V:S264	3.56	No	No	0	5	4
544	V:V:F269	V:V:K271	8.69	No	No	7	4	8
545	V:V:K271	V:V:Y273	23.89	No	Yes	7	8	4
546	V:V:P277	V:V:T276	3.5	No	No	0	9	4
547	V:V:D281	V:V:N282	5.39	No	No	0	4	9
548	V:V:K285	V:V:N282	5.6	No	No	0	7	9
549	V:V:L288	V:V:L290	4.15	No	Yes	1	6	9
550	V:V:A289	V:V:V320	3.39	No	Yes	5	9	9
551	V:V:L290	V:V:T299	4.42	Yes	Yes	1	9	8
552	V:V:D291	V:V:T299	4.34	No	Yes	0	9	8
553	V:V:D291	V:V:N300	6.73	No	No	0	9	9
554	V:V:D291	V:V:S303	5.89	No	No	0	9	9
555	V:V:E297	V:V:K293	5.4	Yes	No	1	5	6
556	V:V:K293	V:V:T299	7.51	No	Yes	1	6	8
557	V:V:E297	V:V:L294	9.28	Yes	Yes	1	5	7
558	V:V:H355	V:V:L294	3.86	Yes	Yes	1	1	7
559	V:V:E297	V:V:T299	4.23	Yes	Yes	1	5	8
560	V:V:D298	V:V:E357	15.59	No	No	0	9	1
561	V:V:H346	V:V:N300	7.65	No	No	20	7	9
562	V:V:L301	V:V:Y322	5.86	No	Yes	0	9	9
563	V:V:A302	V:V:V320	5.09	No	Yes	0	9	9
564	V:V:S304	V:V:V343	3.23	No	No	0	8	4
565	V:V:L319	V:V:T305	4.42	No	No	0	5	9
566	V:V:V320	V:V:Y322	5.05	Yes	Yes	5	9	9
567	V:V:F342	V:V:Y322	6.19	No	Yes	5	6	9
568	V:V:L344	V:V:Y322	7.03	No	Yes	0	8	9
569	V:V:E339	V:V:R323	19.77	No	No	21	7	5
570	V:V:P341	V:V:R323	10.09	No	No	0	9	5
571	V:V:L340	V:V:V324	4.47	Yes	No	0	6	7
572	V:V:K325	V:V:S337	9.18	No	No	0	7	3
573	V:V:K327	V:V:V329	4.55	No	No	0	7	4
574	V:V:D335	V:V:K327	9.68	No	No	0	7	7
575	V:V:L328	V:V:V336	4.47	No	No	0	6	7
576	V:V:H346	V:V:P347	4.58	No	No	0	7	8
577	V:V:K348	V:V:P349	3.35	No	No	0	7	8
578	V:V:E351	V:V:K350	13.5	No	No	0	1	1
579	V:V:E352	V:V:P353	3.14	Yes	No	0	1	1
580	V:V:E352	V:V:H355	4.92	Yes	Yes	1	1	1
581	V:V:P354	V:V:V358	3.53	No	No	0	1	1
582	V:V:H355	V:V:R356	3.39	Yes	No	0	1	1
583	V:V:E360	V:V:R356	8.14	No	No	0	1	1
584	V:V:P359	V:V:V358	5.3	No	No	0	1	1
585	V:V:K171	V:V:S126	3.06	No	No	0	9	7
586	V:V:K233	V:V:S235	3.06	No	No	0	6	5
587	V:V:K227	V:V:V229	3.04	No	No	0	8	8
588	V:V:M345	V:V:V343	3.04	No	No	0	7	4
589	L:L:A55	L:L:Q26	3.03	No	No	0	6	8
590	V:V:F62	V:V:G142	3.01	Yes	No	0	9	9
591	V:V:F76	V:V:G65	3.01	No	No	0	9	9
592	L:L:G29	L:L:R28	3	No	No	0	6	7
593	R:R:L288	R:R:S41	3	No	No	0	5	5
594	V:V:L19	V:V:S14	3	No	Yes	0	5	7
595	V:V:L278	V:V:S280	3	No	No	0	3	4
596	R:R:L303	R:R:V251	2.98	No	No	0	8	7
597	V:V:L19	V:V:V44	2.98	No	No	0	5	4
598	V:V:L49	V:V:V44	2.98	No	No	0	5	4
599	V:V:L200	V:V:V326	2.98	No	No	0	5	7
600	V:V:L208	V:V:V343	2.98	No	No	0	4	4
601	V:V:L301	V:V:V254	2.98	No	No	0	9	9
602	V:V:L340	V:V:V338	2.98	Yes	Yes	0	6	7
603	V:V:N123	V:V:V315	2.96	No	No	0	6	5
604	V:V:N216	V:V:V272	2.96	No	No	0	4	5
605	R:R:T247	V:V:L72	2.95	No	Yes	0	7	7
606	R:R:L264	R:R:T260	2.95	No	No	0	5	5
607	R:R:I60	R:R:I81	2.94	No	No	0	7	5
608	R:R:I81	R:R:I85	2.94	No	No	0	5	6
609	R:R:I168	R:R:I213	2.94	No	No	0	5	4
610	R:R:I107	R:R:K111	2.91	No	No	0	4	7
611	R:R:I156	R:R:K152	2.91	No	No	0	3	5
612	R:R:W259	R:R:Y262	2.89	Yes	No	0	8	6
613	V:V:P253	V:V:R237	2.88	No	Yes	0	3	6
614	L:L:Q134	R:R:V179	2.87	No	Yes	0	6	1
615	R:R:K234	R:R:K235	2.87	No	No	0	5	4
616	R:R:I302	R:R:L299	2.85	No	No	0	6	7
617	R:R:G106	R:R:W103	2.81	No	Yes	0	7	9
618	V:V:K18	V:V:N16	2.8	Yes	No	0	5	8
619	L:L:F156	R:R:A117	2.77	Yes	No	6	9	6
620	R:R:A117	R:R:F86	2.77	No	Yes	6	6	7
621	V:V:L167	V:V:L23	2.77	No	No	0	8	8
622	V:V:H114	V:V:V44	2.77	No	No	0	3	4
623	V:V:D47	V:V:K50	2.77	No	No	0	4	4
624	V:V:A83	V:V:F81	2.77	No	No	0	4	5
625	V:V:A83	V:V:F118	2.77	No	Yes	0	4	8
626	V:V:L279	V:V:L290	2.77	No	Yes	0	8	9
627	R:R:L87	R:R:N56	2.75	No	Yes	0	6	9
628	V:V:D281	V:V:L278	2.71	No	No	0	4	3
629	V:V:A87	V:V:Y85	2.67	No	Yes	0	5	3
630	L:L:L72	L:L:Q74	2.66	Yes	No	0	8	9
631	L:L:E49	L:L:L34	2.65	No	No	0	6	8
632	R:R:F115	R:R:S166	2.64	No	No	0	6	4
633	R:R:E25	R:R:N182	2.63	No	No	0	7	3
634	V:V:F174	V:V:V172	2.62	No	No	0	5	6
635	V:V:S321	V:V:Y239	2.54	No	Yes	0	8	3
636	R:R:V252	R:R:Y226	2.52	No	Yes	0	7	9
637	R:R:F160	R:R:L164	2.44	No	No	0	3	4
638	R:R:F217	R:R:L216	2.44	No	No	0	6	4
639	R:R:F84	R:R:N56	2.42	No	Yes	0	7	9
640	R:R:F181	R:R:N182	2.42	Yes	No	0	4	3
641	V:V:D144	V:V:R63	2.38	No	No	0	8	8
642	R:R:Q312	R:R:R316	2.34	No	No	0	8	6
643	V:V:L257	V:V:Y273	2.34	No	Yes	0	4	4
644	R:R:L249	R:R:W246	2.28	No	No	0	4	6
645	L:L:F60	L:L:R140	2.14	Yes	No	0	4	4
646	V:V:F117	V:V:Y85	2.06	No	Yes	0	4	3
647	R:R:G55	R:R:P54	2.03	No	No	0	7	4
648	V:V:G180	V:V:P179	2.03	No	No	0	4	4
649	V:V:P97	V:V:P98	1.95	No	No	0	3	4
650	V:V:P353	V:V:P354	1.95	No	No	0	1	1
651	V:V:G17	V:V:S13	1.86	No	No	0	5	5
652	L:L:G112	L:L:V110	1.84	No	No	0	5	8
653	V:V:G212	V:V:T276	1.82	No	No	0	9	4
654	R:R:A48	R:R:C298	1.81	No	No	0	6	7
655	L:L:A100	L:L:A33	1.79	No	No	0	8	7
656	R:R:A123	R:R:A165	1.79	No	No	0	6	8
657	R:R:P196	R:R:T199	1.75	No	No	0	1	6
658	V:V:P214	V:V:T274	1.75	No	No	0	4	4
659	L:L:G63	L:L:K103	1.74	No	No	0	9	9
660	L:L:G29	L:L:L68	1.71	No	No	0	6	8
661	L:L:A155	L:L:S157	1.71	No	Yes	0	9	5
662	R:R:G52	R:R:L51	1.71	No	No	0	8	5
663	R:R:G52	R:R:L87	1.71	No	No	0	8	6
664	R:R:C258	R:R:V257	1.71	No	No	0	7	5
665	V:V:G65	V:V:L141	1.71	No	No	0	9	7
666	V:V:G110	V:V:L109	1.71	No	Yes	0	9	7
667	R:R:V143	V:V:A248	1.7	No	No	0	5	6
668	V:V:A185	V:V:V338	1.7	No	Yes	0	6	7
669	V:V:A140	V:V:T129	1.68	No	No	0	6	6
670	V:V:K178	V:V:P179	1.67	No	No	0	2	4
671	L:L:G152	L:L:Q153	1.64	No	Yes	0	9	6
672	R:R:C228	R:R:I224	1.64	No	No	0	4	4
673	V:V:L340	V:V:P341	1.64	Yes	No	0	6	9
674	R:R:S124	R:R:V125	1.62	No	No	0	9	7
675	V:V:A248	V:V:I242	1.62	No	Yes	0	6	7
676	V:V:D47	V:V:P46	1.61	No	No	0	4	5
677	L:L:S76	L:L:T75	1.6	No	No	0	3	9
678	R:R:V36	R:R:V40	1.6	No	No	0	3	6
679	R:R:V205	R:R:V209	1.6	No	No	0	3	2
680	R:R:V252	R:R:V256	1.6	No	No	0	7	5
681	R:R:V253	R:R:V257	1.6	No	No	0	5	5
682	V:V:S270	V:V:T268	1.6	No	No	0	5	7
683	V:V:T247	V:V:V243	1.59	No	No	0	6	6
684	R:R:A254	R:R:L299	1.58	No	No	0	7	7
685	R:R:A254	R:R:L303	1.58	No	No	0	7	8
686	V:V:P132	V:V:Q131	1.58	No	No	0	7	9
687	V:V:E357	V:V:P359	1.57	No	No	0	1	1
688	L:L:S147	R:R:I272	1.55	No	No	0	3	2
689	R:R:I201	R:R:V205	1.54	No	No	0	1	3
690	R:R:I213	R:R:V209	1.54	No	No	0	4	2
691	R:R:S241	V:V:K78	1.53	No	No	0	7	9
692	V:V:K231	V:V:V329	1.52	No	No	0	5	4
693	R:R:F65	R:R:G64	1.51	No	Yes	0	4	3
694	L:L:K71	L:L:T50	1.5	No	No	0	4	7
695	R:R:L119	R:R:S166	1.5	No	No	0	5	4
696	R:R:L167	R:R:S166	1.5	No	No	0	4	4
697	R:R:L219	R:R:S223	1.5	No	No	0	6	3
698	V:V:G287	V:V:R286	1.5	No	No	0	9	5
699	R:R:L288	R:R:V40	1.49	No	No	0	5	6
700	R:R:L51	R:R:V50	1.49	No	No	0	5	4
701	R:R:L144	R:R:V143	1.49	No	No	0	5	5
702	V:V:N218	V:V:S203	1.49	No	No	0	5	6
703	V:V:L319	V:V:V315	1.49	No	No	0	5	5
704	V:V:N218	V:V:V272	1.48	No	No	0	5	5
705	R:R:F217	R:R:P218	1.44	No	Yes	0	6	9
706	V:V:K233	V:V:K327	1.44	No	No	0	6	7
707	R:R:I159	R:R:L155	1.43	No	No	0	3	4
708	R:R:I159	R:R:L163	1.43	No	No	0	3	4
709	V:V:I318	V:V:L130	1.43	Yes	No	0	8	8
710	L:L:Q73	L:L:T50	1.42	No	No	0	7	7
711	V:V:E146	V:V:T59	1.41	No	No	0	6	7
712	L:L:A141	L:L:F148	1.39	No	No	0	6	1
713	L:L:L34	L:L:L72	1.38	No	Yes	0	8	8
714	R:R:L163	R:R:L167	1.38	No	No	0	4	4
715	R:R:L295	R:R:L299	1.38	No	No	0	5	7
716	V:V:D51	V:V:K50	1.38	No	No	0	3	4
717	V:V:D33	V:V:L32	1.36	No	No	0	4	5
718	L:L:L136	L:L:Q139	1.33	No	No	0	3	5
719	R:R:H141	R:R:I137	1.33	No	No	0	6	5
720	V:V:N123	V:V:Q122	1.32	No	No	0	6	4
721	L:L:R67	L:L:V56	1.31	No	No	0	6	1
722	R:R:H148	R:R:L144	1.29	No	No	0	3	5
723	V:V:R100	V:V:T99	1.29	No	No	0	4	8
724	R:R:S242	R:R:W246	1.24	No	No	0	5	6
725	R:R:K1367	V:V:R104	1.24	No	Yes	0	5	6
726	V:V:K153	V:V:R52	1.24	No	No	0	4	6
727	V:V:K251	V:V:R237	1.24	No	Yes	0	5	6
728	V:V:E201	V:V:H220	1.23	No	No	0	7	4
729	R:R:F231	R:R:L227	1.22	No	No	0	3	3
730	V:V:L279	V:V:R283	1.21	No	No	0	8	6
731	R:R:?1357	V:V:K295	1.2	Yes	No	0	6	8
732	R:R:H204	R:R:H274	1.19	No	No	0	4	3
733	R:R:I107	R:R:W108	1.17	No	No	0	4	1
734	V:V:H160	V:V:R162	1.13	No	No	0	5	7
735	V:V:R104	V:V:R107	1.07	Yes	No	0	6	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:F60	7.755	4	0	4
2	L:L:F65	12.3525	4	0	8
3	L:L:L72	3.4175	4	0	8
4	L:L:C101	5.5	4	13	9
5	L:L:L114	6.3675	4	13	7
6	L:L:Y149	7.368	5	3	5
7	L:L:F150	7.364	5	3	4
8	L:L:Q153	5.306	5	3	6
9	L:L:F154	6.842	5	3	6
10	L:L:F156	6.4675	4	6	9
11	L:L:S157	4.0825	4	9	5
12	R:R:Y21	10.322	5	12	3
13	R:R:Y45	5.92833	6	6	8
14	R:R:N56	4.605	4	14	9
15	R:R:F62	7.08	4	0	7
16	R:R:T63	3.602	5	8	7
17	R:R:G64	3.015	4	8	3
18	R:R:W67	6.46667	6	8	6
19	R:R:T70	4.86	4	0	7
20	R:R:V71	7.2675	4	4	6
21	R:R:W75	5.644	5	4	7
22	R:R:D83	5.685	4	14	9
23	R:R:F86	7.5975	4	6	7
24	R:R:Y93	8.195	4	6	6
25	R:R:W103	8.88333	6	9	9
26	R:R:Q118	4.76	4	0	5
27	R:R:N120	5.8175	4	0	8
28	R:R:F122	4.865	4	0	6
29	R:R:F127	5.644	5	4	7
30	R:R:L139	5.93	4	0	8
31	R:R:R149	8.7275	4	4	7
32	R:R:I158	5.725	4	4	7
33	R:R:I161	4.99	4	0	7
34	R:R:W162	5.07	4	4	9
35	R:R:R176	5.92	4	9	4
36	R:R:V179	4.7375	4	3	1
37	R:R:F181	4.79	5	0	4
38	R:R:Y188	9.86	5	3	3
39	R:R:F191	9.2775	4	0	5
40	R:R:Y215	11.7625	4	15	8
41	R:R:P218	3.1325	4	0	9
42	R:R:Y226	6.7525	4	0	9
43	R:R:W259	6.205	6	0	8
44	R:R:L270	8.1325	4	0	5
45	R:R:Y277	11.925	4	0	1
46	R:R:M282	8.586	5	3	4
47	R:R:I286	4.908	5	3	4
48	R:R:Y304	5.72	4	0	9
49	R:R:F311	5.3725	4	0	8
50	R:R:?1357	5.2175	4	0	6
51	R:R:?1362	10.81	4	2	4
52	R:R:?1363	12.2614	7	2	7
53	R:R:?1364	11.405	4	2	5
54	R:R:L1365	8.8575	4	2	5
55	V:V:K11	7.79	4	2	9
56	V:V:S14	5.125	4	0	7
57	V:V:K18	11.6525	4	16	5
58	V:V:Y22	7.44	6	2	9
59	V:V:R26	7.9225	4	0	9
60	V:V:F28	8.245	4	1	8
61	V:V:Y48	7.686	5	16	5
62	V:V:F55	5.9475	4	10	3
63	V:V:F62	5.49167	6	17	9
64	V:V:L72	4.4925	4	0	7
65	V:V:L74	5.3825	4	0	7
66	V:V:Y85	2.7275	4	11	3
67	V:V:R104	4.9275	4	2	6
68	V:V:L109	6.9125	4	2	7
69	V:V:F116	5.35	5	11	9
70	V:V:F118	4.794	5	11	8
71	V:V:I120	5.3925	4	0	5
72	V:V:P125	5.2775	4	0	9
73	V:V:F150	7.165	4	10	5
74	V:V:R170	9.1225	4	1	9
75	V:V:H199	8.3475	4	0	5
76	V:V:L204	5.3425	4	0	7
77	V:V:Y209	7.88667	6	5	7
78	V:V:H211	12.51	4	20	9
79	V:V:R237	6.0775	4	0	6
80	V:V:Y239	7.472	5	21	3
81	V:V:I242	5.865	4	17	7
82	V:V:Q259	12.6075	4	7	5
83	V:V:D261	10.235	4	7	7
84	V:V:V263	4.415	6	7	6
85	V:V:Y273	12.9	4	7	4
86	V:V:L290	4.8325	4	1	9
87	V:V:L294	7.88	4	1	7
88	V:V:E297	5.6	4	1	5
89	V:V:T299	5.125	4	1	8
90	V:V:I318	5.005	4	17	8
91	V:V:V320	4.4575	4	5	9
92	V:V:Y322	8.434	5	5	9
93	V:V:V338	3.85	4	0	7
94	V:V:L340	3.594	5	0	6
95	V:V:E352	5.36	4	1	1
96	V:V:H355	7.408	5	1	1

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:R113	R:R:E25	12.822	8.14	No	No	0	7	7
2	R:R:E25	R:R:N182	13.1838	2.63	No	No	0	7	3
3	R:R:F181	R:R:N182	13.5454	2.42	Yes	No	0	4	3
4	L:L:F150	L:L:Q153	14.271	3.51	Yes	Yes	3	4	6
5	L:L:F154	L:L:Q153	22.1253	12.88	Yes	Yes	3	6	6
6	L:L:F154	R:R:I286	23.168	7.54	Yes	Yes	3	6	4
7	R:R:C110	R:R:R176	11.9643	5.57	No	Yes	9	9	4
8	L:L:S157	R:R:R176	11.6445	3.95	Yes	Yes	9	5	4
9	R:R:K210	R:R:Q118	15.4679	5.42	No	Yes	0	6	5
10	R:R:F265	R:R:I286	26.6418	3.77	No	Yes	0	4	4
11	R:R:F265	R:R:S289	26.9881	5.28	No	No	0	4	7
12	R:R:P261	R:R:S289	27.1663	3.56	No	No	0	9	7
13	R:R:L292	R:R:P261	27.31	3.28	No	No	0	7	9
14	R:R:C258	R:R:L292	27.4712	4.76	No	No	0	7	7
15	R:R:C258	R:R:N296	27.9633	3.15	No	No	0	7	9
16	R:R:N296	R:R:N300	38.6835	12.26	No	No	0	9	9
17	R:R:L128	R:R:N300	38.8264	5.49	No	No	0	9	9
18	R:R:L128	R:R:L79	13.5522	4.15	No	No	0	9	9
19	R:R:L128	R:R:Y304	50.6748	8.21	No	Yes	0	9	9
20	R:R:F122	R:R:K210	25.5705	3.72	Yes	No	0	6	6
21	R:R:F122	R:R:F126	22.6732	3.22	Yes	No	0	6	5
22	R:R:F126	R:R:I161	23.9975	6.28	No	Yes	0	5	7
23	R:R:F127	R:R:I161	25.3391	7.54	Yes	Yes	0	7	7
24	R:R:F127	R:R:I158	20.6146	3.77	Yes	Yes	4	7	7
25	R:R:I158	R:R:W75	12.4929	4.7	Yes	Yes	4	7	7
26	R:R:V71	R:R:W75	12.7116	7.36	Yes	Yes	4	6	7
27	R:R:T70	R:R:V71	25.6451	3.17	Yes	Yes	0	7	6
28	R:R:I158	R:R:S154	12.1695	3.1	Yes	No	4	7	7
29	R:R:S154	R:R:V71	12.2946	8.08	No	Yes	4	7	6
30	R:R:T70	V:V:E67	36.1976	7.06	Yes	No	0	7	7
31	R:R:N296	R:R:W259	11.0345	6.78	No	Yes	0	9	8
32	R:R:Y304	V:V:L72	51.8919	4.69	Yes	Yes	0	9	7
33	R:R:S132	R:R:Y226	10.2406	10.17	No	Yes	0	9	9
34	V:V:L72	V:V:V71	54.3592	4.47	Yes	No	0	7	9
35	R:R:H135	V:V:V71	54.4614	5.54	No	No	0	9	9
36	R:R:H135	R:R:L139	58.3177	9	No	Yes	0	9	8
37	R:R:L139	V:V:F245	61.9433	3.65	Yes	No	0	8	6
38	V:V:F245	V:V:L244	62.2886	4.87	No	No	0	6	7
39	V:V:F62	V:V:L244	100	8.53	Yes	No	0	9	7
40	V:V:L74	V:V:Y64	37.2298	5.86	Yes	No	0	7	8
41	V:V:F62	V:V:L80	64.8108	4.87	Yes	No	0	9	7
42	V:V:L80	V:V:V60	28.783	5.96	No	No	0	7	7
43	V:V:F145	V:V:V60	28.73	7.87	No	No	0	7	7
44	V:V:F145	V:V:K171	28.6962	7.44	No	No	0	7	9
45	V:V:I120	V:V:K171	28.2435	4.36	Yes	No	0	5	9
46	V:V:I120	V:V:V38	83.0756	3.07	Yes	No	0	5	7
47	V:V:F28	V:V:V38	82.3409	14.42	Yes	No	1	8	7
48	V:V:F28	V:V:K25	81.8486	7.44	Yes	No	1	8	8
49	V:V:E352	V:V:K25	81.957	4.05	Yes	No	1	1	8
50	V:V:E352	V:V:H355	78.8694	4.92	Yes	Yes	1	1	1
51	V:V:H355	V:V:R26	13.7543	10.16	Yes	Yes	0	1	9
52	R:R:?1357	V:V:K12	11.687	8.39	Yes	No	0	6	9
53	V:V:L80	V:V:P125	36.0733	3.28	No	Yes	0	7	9
54	V:V:L124	V:V:P125	72.1584	4.93	No	Yes	0	6	9
55	V:V:L124	V:V:P121	55.4766	4.93	No	No	18	6	7
56	V:V:I120	V:V:P121	55.571	3.39	Yes	No	0	5	7
57	V:V:F62	V:V:V143	36.1741	5.24	Yes	No	0	9	9
58	V:V:P125	V:V:V143	36.3283	8.84	Yes	No	0	9	9
59	V:V:F81	V:V:L124	16.5653	4.87	No	No	18	5	6
60	V:V:A83	V:V:F81	16.6013	2.77	No	No	0	4	5
61	V:V:A83	V:V:F118	16.4404	2.77	No	Yes	0	4	8
62	V:V:F116	V:V:F118	16.5671	3.22	Yes	Yes	11	9	8
63	R:R:?1357	V:V:R166	13.2563	7.23	Yes	No	0	6	5
64	V:V:H355	V:V:L294	68.8475	3.86	Yes	Yes	1	1	7
65	V:V:E146	V:V:R166	12.4296	15.12	No	No	0	6	5
66	V:V:F76	V:V:L74	36.9181	6.09	No	Yes	0	9	7
67	V:V:E67	V:V:F76	36.3396	5.83	No	No	0	7	9
68	V:V:E297	V:V:L294	69.673	9.28	Yes	Yes	1	5	7
69	V:V:E297	V:V:T299	68.8366	4.23	Yes	Yes	1	5	8
70	V:V:D291	V:V:T299	67.1588	4.34	No	Yes	0	9	8
71	V:V:D291	V:V:N300	33.8812	6.73	No	No	0	9	9
72	V:V:H211	V:V:N300	32.747	11.48	Yes	No	20	9	9
73	V:V:H211	V:V:L344	64.9758	10.29	Yes	No	0	9	8
74	V:V:L344	V:V:Y322	64.4147	7.03	No	Yes	0	8	9
75	V:V:F342	V:V:Y322	55.4045	6.19	No	Yes	5	6	9
76	V:V:F342	V:V:Y209	54.262	4.13	No	Yes	5	6	7
77	V:V:L204	V:V:Y209	42.911	4.69	Yes	Yes	0	7	7
78	V:V:D291	V:V:S303	33.0198	5.89	No	No	0	9	9
79	V:V:H211	V:V:S303	32.7473	5.58	Yes	No	0	9	9
80	V:V:L204	V:V:L340	37.1922	4.15	Yes	Yes	0	7	6
81	V:V:L340	V:V:V338	18.724	2.98	Yes	Yes	0	6	7
82	V:V:L200	V:V:V338	16.9795	5.96	No	Yes	0	5	7
83	V:V:L200	V:V:L328	14.65	12.46	No	No	0	5	6
84	V:V:L198	V:V:L328	12.9002	5.54	No	No	0	6	6
85	V:V:K227	V:V:L198	12.3164	5.64	No	No	0	8	6
86	V:V:K227	V:V:V229	11.7324	3.04	No	No	0	8	8
87	V:V:V229	V:V:V263	11.1482	3.21	No	Yes	0	8	6
88	V:V:L340	V:V:P341	15.2327	1.64	Yes	No	0	6	9
89	V:V:P341	V:V:R323	14.65	10.09	No	No	0	9	5
90	V:V:R323	V:V:Y239	13.4808	14.4	No	Yes	21	5	3
91	R:R:F127	R:R:L79	10.8027	3.65	Yes	No	0	7	9
92	L:L:S157	R:R:Q118	13.5086	5.78	Yes	Yes	0	5	5
93	V:V:L244	V:V:Y64	37.6478	5.86	No	No	0	7	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:E36	R:R:Y21	14.59	12	No	Yes	5	3	0	1
L:L:F37	R:R:Y21	9.28	0	No	Yes	8	3	0	1
L:L:H40	R:R:Y21	8.71	0	No	Yes	8	3	0	1
L:L:G112	R:R:S26	3.71	0	No	No	5	4	0	1
L:L:R113	R:R:E25	8.14	0	No	No	7	7	0	1
L:L:L114	R:R:L24	8.3	13	Yes	No	7	4	0	1
L:L:V115	R:R:Y21	6.31	12	No	Yes	3	3	0	1
L:L:H116	R:R:D20	11.35	0	No	No	8	2	0	1
L:L:H116	R:R:Y22	7.62	0	No	No	8	5	0	1
L:L:Q134	R:R:Y22	7.89	0	No	No	6	5	0	1
L:L:Q134	R:R:L24	5.32	0	No	No	6	4	0	1
L:L:R137	R:R:Q192	5.84	0	No	No	5	4	0	1
L:L:F148	R:R:S26	10.57	0	No	No	1	4	0	1
L:L:F148	R:R:F181	7.5	0	No	Yes	1	4	0	1
L:L:Y149	R:R:E269	8.98	3	Yes	No	5	4	0	1
L:L:Y149	R:R:I272	7.25	3	Yes	No	5	2	0	1
L:L:Y149	R:R:M282	11.97	3	Yes	Yes	5	4	0	1
L:L:F150	R:R:V179	3.93	3	Yes	Yes	4	1	0	1
L:L:F150	R:R:F181	4.29	3	Yes	Yes	4	4	0	1
L:L:F150	R:R:Y188	15.47	3	Yes	Yes	4	3	0	1
L:L:P151	R:R:Y188	5.56	0	No	Yes	9	3	0	1
L:L:Q153	R:R:L186	3.99	3	Yes	No	6	3	0	1
L:L:F154	R:R:M282	4.98	3	Yes	Yes	6	4	0	1
L:L:F154	R:R:Q283	4.68	3	Yes	No	6	3	0	1
L:L:F154	R:R:I286	7.54	3	Yes	Yes	6	4	0	1
L:L:F156	R:R:F86	4.29	6	Yes	Yes	9	7	0	1
L:L:F156	R:R:Y93	12.38	6	Yes	Yes	9	6	0	1
L:L:F156	R:R:F294	6.43	6	Yes	No	9	7	0	1
L:L:S157	R:R:S114	4.89	9	Yes	No	5	5	0	1
L:L:S157	R:R:Q118	5.78	9	Yes	Yes	5	5	0	1
L:L:S157	R:R:R176	3.95	9	Yes	Yes	5	4	0	1
R:R:S23	R:R:Y21	12.72	0	No	Yes	5	3	2	1
R:R:F181	R:R:L28	4.87	0	Yes	No	4	2	1	2
R:R:Y45	R:R:Y93	8.94	6	Yes	Yes	8	6	2	1
R:R:T290	R:R:Y45	7.49	6	No	Yes	6	8	2	2
R:R:F86	R:R:N120	7.25	6	Yes	Yes	7	8	1	2
R:R:F294	R:R:F86	16.08	6	No	Yes	7	7	1	1
R:R:F294	R:R:L90	9.74	6	No	No	7	7	1	2
R:R:Y93	R:R:Y96	3.97	6	Yes	No	6	6	1	2
R:R:T290	R:R:Y93	7.49	6	No	Yes	6	6	2	1
R:R:C110	R:R:R176	5.57	9	No	Yes	9	4	2	1
R:R:R176	R:R:S114	10.54	9	Yes	No	4	5	1	1
R:R:G169	R:R:Q118	3.29	0	No	Yes	7	5	2	1
R:R:A172	R:R:Q118	4.55	0	No	Yes	4	5	2	1
R:R:K210	R:R:Q118	5.42	0	No	Yes	6	5	2	1
R:R:N189	R:R:R176	3.62	0	No	Yes	4	4	2	1
R:R:D177	R:R:V179	5.84	3	No	Yes	5	1	2	1
R:R:D177	R:R:Y188	11.49	3	No	Yes	5	3	2	1
R:R:D177	R:R:N190	14.81	3	No	No	5	3	2	2
R:R:V179	R:R:Y188	6.31	3	Yes	Yes	1	3	1	1
R:R:F181	R:R:L186	4.87	0	Yes	No	4	3	1	1
R:R:N190	R:R:Y188	10.47	3	No	Yes	3	3	2	1
R:R:Q192	R:R:T199	7.09	0	No	No	4	6	1	2
R:R:F265	R:R:I286	3.77	0	No	Yes	4	4	2	1
R:R:E269	R:R:M282	10.83	3	No	Yes	4	4	1	1
R:R:E269	R:R:I286	5.47	3	No	Yes	4	4	1	1
R:R:I272	R:R:Y277	14.51	0	No	Yes	2	1	1	2
R:R:M282	R:R:Y277	10.78	3	Yes	Yes	4	1	1	2
R:R:H280	R:R:Q283	3.71	0	No	No	3	3	2	1
R:R:I286	R:R:M282	4.37	3	Yes	Yes	4	4	1	1
R:R:I286	R:R:P287	3.39	3	Yes	No	4	4	1	2
L:L:Q134	R:R:V179	2.87	0	No	Yes	6	1	0	1
L:L:F156	R:R:A117	2.77	6	Yes	No	9	6	0	1
R:R:A117	R:R:F86	2.77	6	No	Yes	6	7	1	1
R:R:E25	R:R:N182	2.63	0	No	No	7	3	1	2
R:R:F181	R:R:N182	2.42	0	Yes	No	4	3	1	2
L:L:S147	R:R:I272	1.55	0	No	No	3	2	0	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	9UYM_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.07
Number of Linked Nodes	655
Number of Links	735
Number of Hubs	96
Number of Links mediated by Hubs	353
Number of Communities	21
Number of Nodes involved in Communities	127
Number of Links involved in Communities	165

Path Summary
Number Of Nodes in MetaPath	94
Number Of Links MetaPath	93
Number of Shortest Paths	996806
Length Of Smallest Path	3
Average Path Length	34.4741
Length of Longest Path	67
Minimum Path Strength	1.155
Average Path Strength	6.03183
Maximum Path Strength	24.595
Minimum Path Correlation	0.7
Average Path Correlation	0.973881
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	2.27273
Average % Of Corr. Nodes	37.6988
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	42.235
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• vasopressin receptor activity • peptide receptor activity • molecular transducer activity • G protein-coupled receptor activity • G protein-coupled peptide receptor activity • signaling receptor activity • transmembrane signaling receptor activity • binding • adipokinetic hormone binding • peptide hormone binding • hormone binding • protein-hormone receptor activity • adipokinetic hormone receptor activity • neuropeptide binding • peptide binding • regulation of body fluid levels • hemostasis • biological regulation • regulation of biological quality • regulation of tube diameter • multicellular organismal process • regulation of biological process • system process • regulation of tube size • regulation of system process • positive regulation of biological process • positive regulation of vasoconstriction • circulatory system process • regulation of blood circulation
Gene Ontology	Biological Process	• regulation of body fluid levels • hemostasis • biological regulation • regulation of biological quality • regulation of tube diameter • multicellular organismal process • regulation of biological process • system process • regulation of tube size • regulation of system process • positive regulation of biological process • positive regulation of vasoconstriction • circulatory system process • regulation of blood circulation • vascular process in circulatory system • regulation of vasoconstriction • positive regulation of multicellular organismal process • regulation of multicellular organismal process • blood vessel diameter maintenance • vasoconstriction • blood circulation • regulation of anatomical structure size • renal system process • transport • homeostatic process • fluid transport • establishment of localization • water transport • renal water transport • localization • multicellular organismal-level homeostasis • chemical homeostasis • renal absorption • multicellular organismal-level water homeostasis • multicellular organismal-level chemical homeostasis • renal water absorption • renal water homeostasis • regulation of biosynthetic process • regulation of cellular process • regulation of macromolecule metabolic process • gene expression • macromolecule biosynthetic process • positive regulation of macromolecule biosynthetic process • regulation of gene expression • positive regulation of metabolic process • biosynthetic process • positive regulation of gene expression • positive regulation of biosynthetic process • regulation of macromolecule biosynthetic process • metabolic process • cellular process • positive regulation of macromolecule metabolic process • macromolecule metabolic process • regulation of metabolic process • positive regulation of cellular process • cellular response to stimulus • response to stimulus • signaling • cell communication • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • signal transduction • cellular response to endogenous stimulus • cellular response to chemical stimulus • response to hormone • response to endogenous stimulus • response to chemical • cellular response to hormone stimulus • response to peptide • response to cytokine • regulation of systemic arterial blood pressure by hormone • regulation of systemic arterial blood pressure mediated by a chemical signal • regulation of blood pressure • regulation of systemic arterial blood pressure • endocrine process • regulation of systemic arterial blood pressure by vasopressin • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cell population proliferation • positive regulation of cell population proliferation • regulation of cell population proliferation • positive regulation of cell communication • regulation of signaling • positive regulation of signal transduction • positive regulation of intracellular signal transduction • regulation of signal transduction • intracellular signal transduction • positive regulation of response to stimulus • regulation of intracellular signal transduction • regulation of response to stimulus • regulation of cell communication • positive regulation of signaling • regulation of urine volume • renal water retention • negative regulation of urine volume • developmental process • head development • forebrain development • animal organ development • brain development • nervous system development • multicellular organism development • central nervous system development • anatomical structure development • telencephalon development • system development • negative regulation of cell population proliferation • negative regulation of cellular process • negative regulation of biological process • positive regulation of adenylate cyclase activity • positive regulation of molecular function • regulation of molecular function • positive regulation of cyclase activity • activation of adenylate cyclase activity • regulation of adenylate cyclase activity • regulation of catalytic activity • positive regulation of catalytic activity • positive regulation of lyase activity • positive regulation of systemic arterial blood pressure • positive regulation of blood pressure • neuropeptide signaling pathway • glucose homeostasis • carbohydrate homeostasis • cellular anatomical structure • membrane • membrane-bounded organelle • intracellular anatomical structure • intracellular vesicle • intracellular organelle • bounding membrane of organelle • cytoplasmic vesicle • vesicle membrane • clathrin-coated vesicle • endocytic vesicle membrane • coated vesicle • vesicle • endocytic vesicle
Gene Ontology	Cellular Component	• cellular anatomical structure • membrane • membrane-bounded organelle • intracellular anatomical structure • intracellular vesicle • intracellular organelle • bounding membrane of organelle • cytoplasmic vesicle • vesicle membrane • clathrin-coated vesicle • endocytic vesicle membrane • coated vesicle • vesicle • endocytic vesicle • clathrin-coated vesicle membrane • clathrin-coated endocytic vesicle membrane • intracellular membrane-bounded organelle • clathrin-coated endocytic vesicle • cytoplasmic vesicle membrane • coated vesicle membrane • organelle • cytoplasm • organelle membrane • cell periphery • plasma membrane • Golgi apparatus • endomembrane system • endosome • perinuclear region of cytoplasm • endoplasmic reticulum • nucleus • membrane-enclosed lumen • intracellular organelle lumen • nucleoplasm • organelle lumen • nuclear lumen • cell projection • neuron projection • plasma membrane bounded cell projection • protein binding • binding • protein kinase B binding • kinase binding • enzyme binding • protein kinase binding • protein-macromolecule adaptor activity • molecular adaptor activity • angiotensin receptor binding • signaling receptor binding • G protein-coupled receptor binding • D1 dopamine receptor binding • dopamine receptor binding • ubiquitin protein ligase binding • ubiquitin-like protein ligase binding • arrestin family protein binding • GTPase regulator activity • enzyme regulator activity • enzyme activator activity • GTPase activator activity • molecular function activator activity • nucleoside-triphosphatase regulator activity • molecular function regulator activity • insulin-like growth factor receptor binding • molecular function inhibitor activity • enzyme inhibitor activity • transcription coactivator activity • transcription regulator activity • transcription coregulator activity • cellular response to nitrogen compound • cellular response to stimulus • response to dopamine • regulation of cellular process • response to stimulus • signaling • cellular response to dopamine • response to monoamine • beta-arrestin-dependent dopamine receptor signaling pathway • cell communication • response to catecholamine • cellular response to catecholamine stimulus • signal transduction • regulation of biological process • cell surface receptor signaling pathway • biological regulation • response to oxygen-containing compound • response to nitrogen compound • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to monoamine stimulus • response to chemical • cellular process • multicellular organismal process • regulation of tumor necrosis factor production • negative regulation of biological process • negative regulation of tumor necrosis factor production • cytokine production • regulation of cytokine production • negative regulation of cellular process • regulation of multicellular organismal process • negative regulation of macromolecule metabolic process • regulation of biosynthetic process • negative regulation of metabolic process • tumor necrosis factor superfamily cytokine production • negative regulation of cytokine production • regulation of macromolecule metabolic process • gene expression • macromolecule biosynthetic process • tumor necrosis factor production • regulation of gene expression • negative regulation of gene expression • regulation of tumor necrosis factor superfamily cytokine production • biosynthetic process • negative regulation of biosynthetic process • negative regulation of macromolecule biosynthetic process • negative regulation of tumor necrosis factor superfamily cytokine production • metabolic process • regulation of macromolecule biosynthetic process • macromolecule metabolic process • negative regulation of multicellular organismal process • regulation of metabolic process • localization • import into cell • receptor internalization • transport • receptor-mediated endocytosis • endocytosis • establishment of localization • vesicle-mediated transport • interleukin-6 production • regulation of interleukin-6 production • negative regulation of interleukin-6 production • negative regulation of post-translational protein modification • regulation of protein modification process • regulation of protein ubiquitination • regulation of primary metabolic process • protein ubiquitination • negative regulation of protein modification process • protein metabolic process • negative regulation of protein ubiquitination • regulation of protein modification by small protein conjugation or removal • protein modification process • negative regulation of protein metabolic process • negative regulation of protein modification by small protein conjugation or removal • regulation of post-translational protein modification • regulation of protein metabolic process • primary metabolic process • macromolecule modification • post-translational protein modification • protein modification by small protein conjugation • protein modification by small protein conjugation or removal • positive regulation of biological process • positive regulation of macromolecule biosynthetic process • positive regulation of metabolic process • positive regulation of gene expression • positive regulation of biosynthetic process • positive regulation of macromolecule metabolic process • positive regulation of cellular process • negative adaptation of signaling pathway • negative regulation of signaling • desensitization of G protein-coupled receptor signaling pathway • regulation of signal transduction • negative regulation of G protein-coupled receptor signaling pathway • negative regulation of cell communication • regulation of G protein-coupled receptor signaling pathway • regulation of signaling • negative regulation of response to stimulus • negative regulation of signal transduction • regulation of response to stimulus • adaptation of signaling pathway • regulation of cell communication • G protein-coupled receptor signaling pathway • trans-synaptic signaling • modulation of chemical synaptic transmission • cell-cell signaling • chemical synaptic transmission • synaptic signaling • regulation of trans-synaptic signaling • anterograde trans-synaptic signaling • cell chemotaxis • chemotaxis • response to external stimulus • taxis • cell migration • cell motility • locomotion • regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction • negative regulation of intracellular signal transduction • negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction • intracellular signal transduction • regulation of intracellular signal transduction • intracellular signaling cassette • phosphatidylinositol 3-kinase/protein kinase B signal transduction • postsynaptic signal transduction • muscle hypertrophy • regulation of muscle adaptation • system process • positive regulation of cardiac muscle hypertrophy • regulation of system process • striated muscle hypertrophy • regulation of muscle system process • muscle system process • regulation of cardiac muscle hypertrophy • regulation of muscle hypertrophy • muscle adaptation • positive regulation of muscle hypertrophy • cardiac muscle hypertrophy • positive regulation of multicellular organismal process • adult walking behavior • adult locomotory behavior • behavior • adult behavior • locomotory behavior • walking behavior • cellular response to growth factor stimulus • cell surface receptor protein serine/threonine kinase signaling pathway • cellular response to transforming growth factor beta stimulus • response to endogenous stimulus • cellular response to endogenous stimulus • response to transforming growth factor beta • transforming growth factor beta receptor signaling pathway • response to growth factor • transforming growth factor beta receptor superfamily signaling pathway • enzyme-linked receptor protein signaling pathway • G protein-coupled receptor internalization • positive regulation of response to biotic stimulus • pattern recognition receptor signaling pathway • toll-like receptor signaling pathway • response to biotic stimulus • immune response-activating signaling pathway • positive regulation of immune response • regulation of immune system process • positive regulation of immune system process • innate immune response-activating signaling pathway • immune response • response to other organism • regulation of innate immune response • defense response to other organism • regulation of pattern recognition receptor signaling pathway • positive regulation of defense response • activation of innate immune response • regulation of immune response • regulation of toll-like receptor signaling pathway • activation of immune response • regulation of defense response • regulation of response to biotic stimulus • biological process involved in interspecies interaction between organisms • regulation of response to external stimulus • positive regulation of response to stimulus • positive regulation of response to external stimulus • immune response-regulating signaling pathway • regulation of response to stress • response to stress • innate immune response • response to external biotic stimulus • positive regulation of innate immune response • defense response • defense response to symbiont • negative regulation of toll-like receptor signaling pathway • negative regulation of immune system process • immune system process • positive regulation of cell communication • positive regulation of signal transduction • positive regulation of ERK1 and ERK2 cascade • positive regulation of MAPK cascade • positive regulation of intracellular signal transduction • regulation of MAPK cascade • MAPK cascade • ERK1 and ERK2 cascade • regulation of ERK1 and ERK2 cascade • positive regulation of signaling • RNA metabolic process • nucleobase-containing compound biosynthetic process • nucleic acid metabolic process • RNA biosynthetic process • nucleobase-containing compound metabolic process • DNA-templated transcription • nucleic acid biosynthetic process • transcription by RNA polymerase II • negative regulation of canonical NF-kappaB signal transduction • canonical NF-kappaB signal transduction • regulation of canonical NF-kappaB signal transduction • establishment of protein localization • protein transport • macromolecule localization • intracellular protein localization • regulation of localization • regulation of cellular component organization • positive regulation of cellular component organization • regulation of receptor internalization • cellular component organization • positive regulation of endocytosis • cellular component organization or biogenesis • positive regulation of receptor-mediated endocytosis • regulation of endocytosis • regulation of transport • regulation of receptor-mediated endocytosis • regulation of vesicle-mediated transport • positive regulation of receptor internalization • positive regulation of transport • interleukin-1 production • regulation of interleukin-1 beta production • negative regulation of interleukin-1 beta production • negative regulation of interleukin-1 production • regulation of interleukin-1 production • interleukin-1 beta production • positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction • catabolic process • proteasomal protein catabolic process • protein catabolic process • proteasome-mediated ubiquitin-dependent protein catabolic process • macromolecule catabolic process • modification-dependent macromolecule catabolic process • modification-dependent protein catabolic process • ubiquitin-dependent protein catabolic process • regulation of immune effector process • lymphocyte mediated immunity • negative regulation of lymphocyte mediated immunity • negative regulation of natural killer cell mediated immunity • leukocyte mediated immunity • natural killer cell mediated immunity • regulation of natural killer cell mediated immunity • negative regulation of immune response • negative regulation of immune effector process • leukocyte mediated cytotoxicity • immune effector process • regulation of leukocyte mediated immunity • negative regulation of response to external stimulus • negative regulation of defense response • natural killer cell mediated cytotoxicity • regulation of cell killing • negative regulation of natural killer cell mediated cytotoxicity • regulation of natural killer cell mediated cytotoxicity • negative regulation of response to biotic stimulus • negative regulation of leukocyte mediated cytotoxicity • negative regulation of cell killing • regulation of leukocyte mediated cytotoxicity • regulation of lymphocyte mediated immunity • negative regulation of leukocyte mediated immunity • cell killing • negative regulation of innate immune response • regulation of postsynaptic membrane potential • chemical synaptic transmission, postsynaptic • regulation of biological quality • nervous system process • excitatory postsynaptic potential • regulation of membrane potential • cellular developmental process • regulation of developmental process • regulation of cell differentiation • regulation of striated muscle cell differentiation • regulation of cardiac muscle cell differentiation • muscle cell differentiation • striated muscle tissue development • muscle structure development • positive regulation of developmental process • multicellular organism development • positive regulation of cell differentiation • positive regulation of cardiocyte differentiation • cell differentiation • positive regulation of striated muscle cell differentiation • anatomical structure development • muscle tissue development • positive regulation of cardiac muscle cell differentiation • system development • developmental process • heart development • cardiac muscle tissue development • animal organ development • cardiac muscle cell differentiation • tissue development • positive regulation of muscle cell differentiation • cardiocyte differentiation • circulatory system development • regulation of muscle cell differentiation • regulation of cardiocyte differentiation • striated muscle cell differentiation • positive regulation of synaptic transmission • regulation of synaptic transmission, dopaminergic • positive regulation of synaptic transmission, dopaminergic • synaptic transmission, dopaminergic • regulation of interleukin-12 production • negative regulation of interleukin-12 production • interleukin-12 production • sensory perception • sensory perception of pain • cellular homeostasis • chemical homeostasis • homeostatic process • glucose homeostasis • carbohydrate homeostasis • intracellular chemical homeostasis • intracellular glucose homeostasis • actomyosin structure organization • actin cytoskeleton organization • actin filament organization • cellular component biogenesis • organelle organization • cellular component assembly • actin filament bundle organization • contractile actin filament bundle assembly • actin filament-based process • actin filament bundle assembly • stress fiber assembly • supramolecular fiber organization • cytoskeleton organization • negative regulation of interleukin-8 production • interleukin-8 production • regulation of interleukin-8 production • positive regulation of DNA-templated transcription • regulation of RNA metabolic process • regulation of nucleobase-containing compound metabolic process • regulation of RNA biosynthetic process • regulation of transcription by RNA polymerase II • positive regulation of transcription by RNA polymerase II • positive regulation of RNA metabolic process • positive regulation of RNA biosynthetic process • regulation of DNA-templated transcription • small GTPase-mediated signal transduction • regulation of small GTPase mediated signal transduction • Rho protein signal transduction • regulation of Rho protein signal transduction • positive regulation of Rho protein signal transduction • positive regulation of small GTPase mediated signal transduction • Notch signaling pathway • negative regulation of Notch signaling pathway • regulation of Notch signaling pathway • positive regulation of phosphorylation • regulation of protein phosphorylation • positive regulation of protein metabolic process • positive regulation of phosphate metabolic process • positive regulation of protein modification process • phosphate-containing compound metabolic process • positive regulation of protein phosphorylation • phosphorus metabolic process • protein phosphorylation • positive regulation of phosphorus metabolic process • phosphorylation • regulation of phosphorus metabolic process • regulation of phosphorylation • clathrin-coated pit • cytosol • synapse • cell junction • glutamatergic synapse • postsynapse • pseudopodium • membraneless organelle • intracellular membraneless organelle • chromatin • chromosome • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • lysosomal membrane • lysosome • Golgi membrane • nuclear body • humoral immune response • antimicrobial humoral response • defense response to fungus • antifungal humoral response • response to fungus • positive regulation of locomotion • regulation of chemotaxis • positive regulation of chemotaxis • regulation of locomotion • response to activity • digestive system development • tube development • embryo development • digestive tract development • embryonic organ development • embryonic digestive tract development • lipid catabolic process • regulation of lipid metabolic process • regulation of catabolic process • regulation of lipid catabolic process • lipid metabolic process • response to nutrient levels • response to caloric restriction • regulation of cell motility • macrophage migration • positive regulation of cell migration • regulation of mononuclear cell migration • regulation of leukocyte chemotaxis • regulation of leukocyte migration • positive regulation of macrophage migration • positive regulation of leukocyte chemotaxis • granulocyte migration • leukocyte migration • macrophage chemotaxis • regulation of granulocyte chemotaxis • regulation of macrophage migration • positive regulation of cell motility • regulation of cell migration • myeloid leukocyte migration • positive regulation of mononuclear cell migration • regulation of macrophage chemotaxis • positive regulation of leukocyte migration • granulocyte chemotaxis • mononuclear cell migration • positive regulation of macrophage chemotaxis • leukocyte chemotaxis • antifungal innate immune response • response to peptide hormone • insulin receptor signaling pathway • cell surface receptor protein tyrosine kinase signaling pathway • response to hormone • cellular response to hormone stimulus • cellular response to peptide hormone stimulus • response to insulin • cellular response to insulin stimulus • defense response to Gram-negative bacterium • defense response to bacterium • response to bacterium • inflammatory response • fat cell differentiation • positive regulation of fat cell differentiation • regulation of fat cell differentiation • positive regulation of systemic arterial blood pressure • regulation of systemic arterial blood pressure • circulatory system process • regulation of blood pressure • positive regulation of blood pressure • blood circulation • diterpenoid metabolic process • retinoid metabolic process • terpenoid metabolic process • isoprenoid metabolic process • defense response to Gram-positive bacterium • vesicle lumen • cytoplasmic vesicle lumen • secretory granule lumen • platelet dense granule lumen • platelet dense granule • secretory granule • secretory vesicle • extracellular matrix • external encapsulating structure • extracellular region • extracellular space
SCOP2	Domain Identifier
SCOP2	Family Identifier
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	SEP
PDB Residues	R:R:?1357 R:R:?1362 R:R:?1363 R:R:?1364
Environment Details	Open EMBL-EBI Page
Code	SEP
Name	Dexfosfoserine
Synonyms	PHOSPHONOSERINE
Identifier
Formula	C3 H8 N O6 P
Molecular Weight	185.072
SMILES
PubChem	57689797
Formal Charge	0
Total Atoms	19
Total Chiral Atoms	1
Total Bonds	18
Total Aromatic Bonds	0


Code	TPO
PDB Residues	R:R:?1359 R:R:?1360
Environment Details	Open EMBL-EBI Page
Code	TPO
Name	PHOSPHOTHREONINE
Synonyms	PHOSPHONOTHREONINE
Identifier
Formula	C4 H10 N O6 P
Molecular Weight	199.099
SMILES
PubChem	139055008
Formal Charge	0
Total Atoms	22
Total Chiral Atoms	2
Total Bonds	21
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	L
Protein	Chemerin-9
UniProt	Q99969
Sequence	>9UYM_nogp_Chain_L E A Q R R G L Q V A L E E F H K H E T S V E S A V D T P F P A G I F V R L E F K L Q Q T S C R K C L A C I K K V L G R L V H C T Q C L R V Q R A G H S F Y F P G Q F A F S Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	R
Protein	Receptor
UniProt	P46091
Sequence	>9UYM_nogp_Chain_R D Y Y S L E S D L G V V H W V S L V L Y C L A F V L G I P G N A I V I W F T G F K W K K T V T T L W F L N L A I A D F I F L L F L P L Y I S Y V A M N F H W P F G I W L C K A N S F T A Q L N M F A S V F F L T V I S L D H Y I H L I H P V L S H R H R T L K N S L I V I I F I W L L A S L I G G P A L Y F R D T V E F N N H T L C Y N N F Q K P D L T L I R H H V L T W V K F I I G Y L F P L L T M S I C Y L C L I F K V K K R S S S R H F W T I L V V V V A F V V C W T P Y H L F S I W E L T I H H N S Y S H H V M Q A G I P L S T G L A F L N S C L N P I L Y V L I S K K F Q A R F R S S ?C ??A ???L A K Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	V
Protein	Arrestin
UniProt	P32121
Sequence	>9UYM_nogp_Chain_V T R V F K K S S P N K L T V Y L G K R D F V D H L D K V D P V D G V V L V D P D Y L K D R K V F V T L T A F R Y G R E D L D V L G L S F R K D L F I A T Y Q A F P P T R L Q D R L L R K L G Q H A H P F F F T I P Q N L P S V T L Q P A G V D F E I R A F A K S H K R N S V R L V I R K V Q F A P E K P G P Q P S A E T T R L H L E A S L D K E L Y Y H G E P L N V N V H V T N N S T K T V K K I K V S V R Q Y A D I L F S T A Q Y K P V A Q L E Q D D Q V S P S S T F K V Y T I T P L L S D N R E K R G L A L D G K L K H E D T N L A S S T I V V L G I L V S Y R V K V K L V D V S V E L P F V L M H P K P P G V S L V V V S K E E P H R E V P E N Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8JJP	A	Protein	Chemerin	CML2	Homo sapiens	Chemerin-9	-	Gi1/β1/γ2	2.9	2024-08-21	doi.org/10.1371/journal.pbio.3002838
	8JJP (No Gprot)	A	Protein	Chemerin	CML2	Homo sapiens	Chemerin-9	-		2.9	2024-08-21	doi.org/10.1371/journal.pbio.3002838
	8XGM	A	Protein	Chemerin	CML2	Homo sapiens	Chemerin	-	Gi1/β1/γ2	3.29	2024-08-21	doi.org/10.1371/journal.pbio.3002838
	8XGM (No Gprot)	A	Protein	Chemerin	CML2	Homo sapiens	Chemerin	-		3.29	2024-08-21	doi.org/10.1371/journal.pbio.3002838
	9L3Y	A	Protein	Chemerin	CML2	Homo sapiens	Chemerin	-	Gi1/β1/γ2	3.6	2025-03-12	doi.org/10.1093/procel/pwae073
	9L3Y (No Gprot)	A	Protein	Chemerin	CML2	Homo sapiens	Chemerin	-		3.6	2025-03-12	doi.org/10.1093/procel/pwae073
	9UYH	A	Protein	Chemerin	CML2	Homo sapiens	Chemerin-9	-	Arrestin2	3.3	2025-11-19	10.1126/science.adt8794
	9UYH (No Gprot)	A	Protein	Chemerin	CML2	Homo sapiens	Chemerin-9	-		3.3	2025-11-19	10.1126/science.adt8794
	9UYI	A	Protein	Chemerin	CML2	Homo sapiens	Chemerin-9	-	Arrestin2	3.2	2025-11-19	10.1126/science.adt8794
	9UYI (No Gprot)	A	Protein	Chemerin	CML2	Homo sapiens	Chemerin-9	-		3.2	2025-11-19	10.1126/science.adt8794
	9UYJ	A	Protein	Chemerin	CML2	Homo sapiens	Chemerin-9	-	Arrestin2	3.3	2025-11-19	10.1126/science.adt8794
	9UYJ (No Gprot)	A	Protein	Chemerin	CML2	Homo sapiens	Chemerin-9	-		3.3	2025-11-19	10.1126/science.adt8794
	9UYL	A	Protein	Chemerin	CML2	Homo sapiens	Chemerin-9	-	Arrestin2	3.3	2025-11-19	10.1126/science.adt8794
	9UYL (No Gprot)	A	Protein	Chemerin	CML2	Homo sapiens	Chemerin-9	-		3.3	2025-11-19	10.1126/science.adt8794
	9UYM	A	Protein	Chemerin	CML2	Homo sapiens	Chemerin-9	-	chim(Arrestin3-CtArrestin2)	3.5	2025-11-19	10.1126/science.adt8794
	9UYM (No Gprot)	A	Protein	Chemerin	CML2	Homo sapiens	Chemerin-9	-		3.5	2025-11-19	10.1126/science.adt8794
	9UYN	A	Protein	Chemerin	CML2	Homo sapiens	-	-	Arrestin2	2.9	2025-11-19	10.1126/science.adt8794
	9UYN (No Gprot)	A	Protein	Chemerin	CML2	Homo sapiens	-	-		2.9	2025-11-19	10.1126/science.adt8794

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