psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	1x29	NT.R54	7.23	No	No	0	5	4
2	1x30	NT.R54	4.28	No	No	0	4	4
3	1x30	1x33	6.01	No	No	0	4	1
4	1x34	1x35	7.31	No	No	0	5	6
5	1x34	1x38	8.71	No	Yes	0	5	5
6	1x35	1x39	11.72	No	Yes	0	6	7
7	1x38	1x39	4.79	Yes	Yes	0	5	7
8	1x38	7x39	6.13	Yes	No	0	5	5
9	1x39	2x57	11.72	Yes	Yes	0	7	8
10	1x39	7x38	6.95	Yes	Yes	0	7	5
11	1x43	2x57	4.76	No	Yes	0	6	8
12	1x45	7x47	6.83	No	No	0	5	7
13	1x45	7x51	3.93	No	No	0	5	6
14	1x46	7x47	3.92	No	No	0	8	7
15	1x47	2x51	4.28	No	No	0	5	7
16	1x47	2x55	4.15	No	No	0	5	4
17	1x49	7x50	4.06	No	No	0	7	9
18	1x50	2x50	10.77	No	Yes	0	9	9
19	1x50	7x50	9.77	No	No	0	9	9
20	1x52	8x54	5.54	No	Yes	0	6	6
21	1x53	7x53	5.05	No	Yes	0	9	9
22	1x56	8x50	7.78	No	Yes	2	6	8
23	1x56	8x54	4.42	No	Yes	2	6	6
24	1x56	Allo3	4.21	No	Yes	2	6	0
25	1x57	I1x48	17.91	Yes	No	4	7	6
26	1x57	I1x51	5.97	Yes	No	4	7	6
27	1x57	2x41	6.24	Yes	No	0	7	5
28	1x57	2x44	16.41	Yes	No	0	7	6
29	1x60	I1x50	3.65	No	No	0	5	7
30	1x60	8x53	21.5	No	No	0	5	5
31	1x60	8x57	3.65	No	No	0	5	5
32	I1x48	I1x51	24.42	No	No	4	6	6
33	8x49	I1x50	4.23	Yes	No	0	7	7
34	2x37	2x39	4.71	No	Yes	2	7	7
35	2x37	2x40	13.01	No	No	2	7	8
36	2x37	Allo3	14.33	No	Yes	2	7	0
37	2x38	2x42	7.18	Yes	Yes	0	6	7
38	2x38	3x49	9.7	Yes	No	0	6	8
39	2x38	4x42	4.6	Yes	No	0	6	8
40	2x39	3x46	4.56	Yes	No	0	7	8
41	2x39	3x49	7.23	Yes	No	0	7	8
42	2x39	Allo3	15.17	Yes	Yes	2	7	0
43	2x40	8x49	8.3	No	Yes	2	8	7
44	2x40	Allo3	25.61	No	Yes	2	8	0
45	2x42	3x45	13.44	Yes	No	0	7	6
46	2x42	3x46	6.04	Yes	No	0	7	8
47	2x42	4x45	5.09	Yes	No	0	7	5
48	2x43	7x53	11.72	No	Yes	2	7	9
49	2x43	Allo3	7.91	No	Yes	2	7	0
50	2x45	4x46	11.02	No	No	0	9	7
51	2x45	4x50	7.91	No	Yes	0	9	9
52	2x46	2x50	4.07	No	Yes	0	9	9
53	2x46	3x42	4.15	No	No	0	9	8
54	2x48	4x50	3.68	No	Yes	0	5	9
55	2x49	4x50	3.89	No	Yes	0	8	9
56	2x50	7x45	10.72	Yes	Yes	1	9	9
57	2x50	7x46	10.89	Yes	Yes	1	9	8
58	2x50	7x49	4.04	Yes	No	1	9	9
59	2x53	2x57	3.65	Yes	Yes	1	6	8
60	2x53	3x32	11.35	Yes	Yes	1	6	6
61	2x53	3x35	5.28	Yes	No	0	6	8
62	2x53	7x42	5.59	Yes	Yes	1	6	7
63	2x53	7x46	4.19	Yes	Yes	1	6	8
64	2x54	7x46	4.76	No	Yes	0	5	8
65	2x56	3x28	6.08	No	No	0	6	5
66	2x57	7x42	6.35	Yes	Yes	1	8	7
67	2x59	E1x52	9.65	No	Yes	0	6	7
68	2x59	3x24	13.93	No	No	0	6	5
69	2x60	E1x50	5.62	Yes	Yes	0	6	9
70	2x60	3x28	10.57	Yes	No	0	6	5
71	2x60	3x29	4.01	Yes	No	0	6	5
72	2x60	7x38	5.79	Yes	Yes	0	6	5
73	2x62	E1x51	6.31	No	No	3	3	2
74	2x62	E1x52	8.25	No	Yes	3	3	7
75	2x63	E1x50	7.41	No	Yes	0	5	9
76	2x63	E2.R209	9.22	No	No	0	5	4
77	E1x50	E1x52	14.03	Yes	Yes	3	9	7
78	3x25	E1x50	3.92	No	Yes	3	9	9
79	E1x50	E2.L199	6.83	Yes	No	0	9	4
80	E1x50	E2x50	20.89	Yes	No	3	9	9
81	E1x51	E1x52	7.87	No	Yes	3	2	7
82	3x22	E2.L199	5.96	No	No	0	2	4
83	3x24	3x27	3.65	No	No	0	5	4
84	3x24	3x28	7.54	No	No	0	5	5
85	3x25	E2x50	7.28	No	No	3	9	9
86	3x29	4x65	13.21	No	No	0	5	5
87	3x29	E2x52	9.74	No	No	0	5	5
88	3x31	3x34	5.83	No	Yes	0	4	5
89	3x32	3x33	4.78	Yes	Yes	1	6	5
90	3x32	6x48	13.53	Yes	Yes	1	6	8
91	3x32	6x51	8.94	Yes	Yes	1	6	6
92	3x32	6x52	10.47	Yes	Yes	1	6	8
93	3x33	3x37	3.72	Yes	No	0	5	7
94	3x33	4x61	10.8	Yes	No	0	5	4
95	3x33	6x52	6.99	Yes	Yes	1	5	8
96	3x34	4x54	6.02	Yes	No	0	5	3
97	3x34	4x57	6.13	Yes	No	0	5	7
98	3x36	3x37	9.65	Yes	No	0	7	7
99	3x36	3x40	4.98	Yes	Yes	1	7	7
100	3x36	5x47	10.72	Yes	Yes	1	7	8
101	3x36	6x48	12.88	Yes	Yes	1	7	8
102	3x36	6x52	12.08	Yes	Yes	1	7	8
103	3x37	5x461	9.03	No	No	0	7	5
104	3x38	3x39	3.71	No	No	0	6	9
105	3x38	4x50	8.65	No	Yes	0	6	9
106	3x39	6x44	4.52	No	Yes	0	9	9
107	3x40	5x47	8.71	Yes	Yes	1	7	8
108	3x40	5x50	6.71	Yes	No	0	7	9
109	3x40	6x44	6.22	Yes	Yes	1	7	9
110	3x41	4x49	4.7	Yes	No	0	5	6
111	3x41	4x52	9.11	Yes	No	0	5	4
112	3x41	5x49	4.9	Yes	No	0	5	5
113	3x41	5x50	16.21	Yes	No	0	5	9
114	3x42	4x49	5.71	No	No	0	8	6
115	3x43	6x41	7.45	No	No	0	8	7
116	3x43	6x44	3.65	No	Yes	0	8	9
117	3x44	3x47	4.5	Yes	Yes	5	7	9
118	3x44	3x48	4.28	Yes	No	0	7	5
119	3x44	5x53	4.73	Yes	No	0	7	7
120	3x44	5x54	7.07	Yes	No	5	7	7
121	3x46	6x37	8.83	No	No	0	8	7
122	3x47	5x54	6.13	Yes	No	5	9	7
123	3x47	5x58	10.17	Yes	Yes	0	9	8
124	3x49	3x50	15.48	No	No	0	8	9
125	3x50	3x53	5.53	No	No	0	9	8
126	3x50	Allo3	11.81	No	Yes	0	9	0
127	3x51	3x55	6.31	Yes	No	0	8	7
128	3x51	5x56	7.22	Yes	No	0	8	3
129	3x51	5x57	4.03	Yes	No	0	8	7
130	4x38	I2x57	3.92	No	No	0	6	7
131	4x43	4x46	6.47	No	No	0	3	7
132	4x59	4x62	4.28	No	No	0	4	4
133	4x60	5x43	4.74	No	Yes	0	8	5
134	4x64	E2.I213	4.84	No	No	0	4	4
135	4x64	5x36	6.19	No	Yes	6	4	4
136	4x64	5x40	4.51	No	No	6	4	5
137	E2.D198	E2.I213	4.2	No	No	0	4	4
138	E2.Q200	E2x51	4.33	No	No	0	3	4
139	E2.S202	E2.S204	6.52	No	No	0	1	6
140	E2.E205	E2.Q206	7.65	No	No	0	4	5
141	E2.I213	E2.V217	7.68	No	No	0	4	2
142	5x34	5x37	5.47	No	No	0	1	2
143	5x36	5x37	11.3	Yes	No	0	4	2
144	5x36	5x40	15.23	Yes	No	6	4	5
145	5x36	6x59	11.67	Yes	No	0	4	4
146	5x38	5x39	4.56	No	No	0	1	4
147	5x39	5x43	4.12	No	Yes	0	4	5
148	5x40	5x43	8.96	No	Yes	0	5	5
149	5x47	5x48	3.65	Yes	No	0	8	4
150	5x47	5x51	8.53	Yes	No	0	8	6
151	5x54	6x41	4.56	No	No	0	7	7
152	5x56	5x60	3.93	No	No	0	3	3
153	5x58	6x37	4.84	Yes	No	0	8	7
154	6x29	6x31	15.77	No	No	0	5	5
155	6x34	6x36	7.68	Yes	No	0	5	7
156	6x34	Allo3	4.08	Yes	Yes	0	5	0
157	6x35	6x38	4.36	No	No	0	5	4
158	6x36	7x56	10.75	No	No	0	7	6
159	6x36	8x47	3.68	No	No	0	7	8
160	6x40	7x49	10.35	No	No	0	8	9
161	6x40	7x52	4.47	No	No	0	8	7
162	6x43	6x47	7.87	No	Yes	0	6	7
163	6x44	6x48	4.68	Yes	Yes	1	9	8
164	6x44	7x45	13.9	Yes	Yes	1	9	9
165	6x46	6x47	5.24	No	Yes	0	5	7
166	6x47	7x40	3.65	Yes	No	0	7	7
167	6x47	7x43	3.93	Yes	No	0	7	5
168	6x47	7x45	8.55	Yes	Yes	0	7	9
169	6x48	7x45	8.18	Yes	Yes	1	8	9
170	6x51	6x52	5.81	Yes	Yes	1	6	8
171	6x51	6x55	8.83	Yes	No	0	6	5
172	6x51	7x34	6.95	Yes	No	0	6	4
173	6x51	7x37	3.75	Yes	Yes	0	6	6
174	6x51	7x38	12.91	Yes	Yes	0	6	5
175	6x54	7x37	6.35	No	Yes	0	5	6
176	6x58	7x30	3.99	No	No	0	5	6
177	7x28	7x32	4.36	No	No	0	3	2
178	7x38	7x42	5.38	Yes	Yes	0	5	7
179	7x45	7x46	5.57	Yes	Yes	1	9	8
180	7x45	7x49	4.82	Yes	No	1	9	9
181	7x53	8x50	4.13	Yes	Yes	2	9	8
182	7x53	Allo3	6.03	Yes	Yes	2	9	0
183	7x55	7x56	6.28	No	No	0	7	6
184	8x49	8x53	11.06	Yes	No	2	7	5
185	8x49	Allo3	22.57	Yes	Yes	2	7	0
186	8x50	8x54	7.31	Yes	Yes	2	8	6
187	8x50	Allo3	4.18	Yes	Yes	2	8	0
188	8x52	8x56	12.59	No	No	0	5	4
189	8x53	Allo3	4.66	No	Yes	2	5	0
190	8x54	8x57	4.15	Yes	No	0	6	5
191	2x62	2x66	3.58	No	No	0	3	4
192	1x33	1x37	3.52	No	No	0	1	5
193	6x50	7x37	3.5	No	Yes	0	9	6
194	3x47	5x57	3.44	Yes	No	0	9	7
195	1x46	2x54	3.42	No	No	0	8	5
196	1x53	2x47	3.39	No	No	0	9	9
197	I2x54	I2x55	3.39	No	No	0	5	4
198	4x59	4x60	3.39	No	No	0	4	8
199	6x28	6x30	3.39	No	No	0	3	6
200	6x54	7x33	3.39	No	No	0	5	5
201	6x58	7x34	3.38	No	No	0	5	4
202	7x23	7x24	3.38	No	No	0	5	5
203	6x49	6x50	3.28	No	No	0	5	9
204	1x42	7x42	3.27	No	Yes	0	6	7
205	1x43	1x47	3.17	No	No	0	6	5
206	6x39	7x52	3.15	No	No	0	5	7
207	1x54	1x58	3.07	No	No	0	7	2
208	5x45	5x46	3.07	No	No	0	4	4
209	6x34	8x48	3.07	Yes	No	0	5	5
210	2x41	4x43	3	No	No	0	5	3
211	1x54	2x44	2.98	No	No	0	7	6
212	2x48	2x52	2.98	No	No	0	5	6
213	5x45	5x48	2.98	No	No	0	4	4
214	7x48	7x52	2.98	No	No	0	6	7
215	3x40	6x45	2.92	Yes	No	0	7	5
216	3x54	5x64	2.91	Yes	No	0	8	5
217	3x54	5x65	2.85	Yes	No	0	8	8
218	3x26	4x62	2.82	No	No	0	7	4
219	4x39	4x43	2.82	No	No	0	2	3
220	3x21	E1x50	2.81	No	Yes	0	7	9
221	3x22	3x23	2.77	No	No	0	2	1
222	4x52	4x56	2.77	No	No	0	4	5
223	5x48	5x52	2.77	No	No	0	4	4
224	7x54	8x50	2.77	No	Yes	0	7	8
225	4x56	5x43	2.66	No	Yes	0	5	5
226	6x58	7x31	2.64	No	No	0	5	4
227	3x51	3x52	2.52	Yes	No	0	8	6
228	1x31	NT.R54	2.48	No	No	0	4	4
229	1x44	1x48	2.44	No	No	0	5	4
230	5x36	6x56	2.44	Yes	No	0	4	5
231	4x40	I2.R170	2.43	No	No	0	4	5
232	3x51	5x61	2.42	Yes	No	0	8	8
233	5x58	5x61	2.42	Yes	No	0	8	8
234	5x58	6x38	2.42	Yes	No	0	8	4
235	3x34	4x50	2.33	Yes	Yes	0	5	9
236	7x34	7x35	2.3	No	No	0	4	5
237	1x43	2x58	1.88	No	No	0	6	9
238	1x36	2x61	1.87	Yes	No	0	6	7
239	1x36	2x64	1.87	Yes	No	0	6	5
240	1x36	2x65	1.87	Yes	No	0	6	4
241	4x48	4x51	1.76	No	No	0	2	4
242	1x48	1x49	1.71	No	No	0	4	7
243	E1x49	E2.A207	1.71	No	No	0	5	1
244	3x38	4x53	1.71	No	No	0	6	7
245	6x53	6x56	1.71	No	No	0	6	5
246	1x35	1x36	1.64	No	Yes	0	6	6
247	3x53	3x54	1.62	No	Yes	0	8	8
248	5x41	5x45	1.6	No	No	0	4	4
249	7x36	7x37	1.59	No	Yes	0	5	6
250	3x30	4x62	1.58	No	No	0	5	4
251	1x41	1x45	1.54	No	No	0	5	5
252	4x47	4x51	1.54	No	No	0	3	4
253	4x51	4x55	1.54	No	No	0	4	4
254	6x38	6x42	1.54	No	No	0	4	4
255	2x38	4x38	1.52	Yes	No	0	6	6
256	6x48	7x41	1.52	Yes	No	0	8	8
257	7x24	7x25	1.52	No	No	0	5	5
258	5x51	5x55	1.5	No	No	0	6	4
259	4x55	4x56	1.49	No	No	0	4	5
260	1x37	1x38	1.46	No	Yes	0	5	5
261	2x38	4x41	1.46	Yes	No	0	6	3
262	E2.Q200	E2.T214	1.42	No	No	0	3	5
263	E2.L199	E2.M208	1.41	No	No	0	4	5
264	5x44	6x56	1.41	No	No	0	5	5
265	7x32	7x35	1.4	No	No	0	2	5
266	7x54	8x51	1.38	No	No	0	7	8
267	5x65	6x31	1.37	No	No	0	8	5
268	7x26	7x29	1.33	No	No	0	3	3
269	E1x49	E2.R209	1.32	No	No	0	5	4
270	E2.R201	E2.S203	1.32	No	No	0	1	2
271	E2.D198	E2.Q200	1.31	No	No	0	4	3
272	3x54	6x30	1.25	Yes	No	0	8	6
273	6x30	6x34	1.25	No	Yes	0	6	5
274	E2.E215	E2.H216	1.23	No	No	0	6	2
275	I2x55	I2x56	1.13	No	No	0	4	3
276	I1x49	I2x57	1.07	No	No	0	6	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg. Int. Strength	Num. Of Links	Community	ConSurf
1	1x36	1.8125	4	0	6
2	1x38	5.2725	4	0	5
3	1x39	8.795	4	0	7
4	1x57	11.6325	4	4	7
5	2x38	4.892	5	0	6
6	2x39	7.9175	4	2	7
7	2x42	7.9375	4	0	7
8	2x50	8.098	5	1	9
9	2x53	6.012	5	1	6
10	2x57	6.62	4	1	8
11	2x60	6.4975	4	0	6
12	E1x50	8.78714	7	3	9
13	E1x52	9.95	4	3	7
14	3x32	9.814	5	1	6
15	3x33	6.5725	4	1	5
16	3x34	5.0775	4	0	5
17	3x36	10.062	5	1	7
18	3x40	5.908	5	1	7
19	3x41	8.73	4	0	5
20	3x44	5.145	4	5	7
21	3x47	6.06	4	5	9
22	3x51	4.5	5	0	8
23	3x54	2.1575	4	0	8
24	4x50	5.292	5	0	9
25	5x36	9.366	5	6	4
26	5x43	5.12	4	0	5
27	5x47	7.9025	4	1	8
28	5x58	4.9625	4	0	8
29	6x34	4.02	4	0	5
30	6x44	6.594	5	1	9
31	6x47	5.848	5	0	7
32	6x48	8.158	5	1	8
33	6x51	7.865	6	1	6
34	6x52	8.8375	4	1	8
35	7x37	3.7975	4	0	6
36	7x38	7.7575	4	0	5
37	7x42	5.1475	4	1	7
38	7x45	8.62333	6	1	9
39	7x46	6.3525	4	1	8
40	7x53	6.7325	4	2	9
41	8x49	11.54	4	2	7
42	8x50	5.234	5	2	8
43	8x54	5.355	4	2	6
44	Allo3	10.96	11	2	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	1x30	1x33	11.0271	6.01	No	No	0	4	1
2	1x33	1x37	13.7565	3.52	No	No	0	1	5
3	1x37	1x38	16.4743	1.46	No	Yes	0	5	5
4	1x38	1x39	24.2701	4.79	Yes	Yes	0	5	7
5	1x35	1x39	16.255	11.72	No	Yes	0	6	7
6	1x39	2x57	25.176	11.72	Yes	Yes	0	7	8
7	1x39	7x38	20.3751	6.95	Yes	Yes	0	7	5
8	1x43	2x57	15.9492	4.76	No	Yes	0	6	8
9	2x53	2x57	38.5632	3.65	Yes	Yes	1	6	8
10	2x53	7x46	30.8656	4.19	Yes	Yes	1	6	8
11	2x54	7x46	10.0346	4.76	No	Yes	0	5	8
12	2x53	3x32	26.0531	11.35	Yes	Yes	1	6	6
13	3x32	6x48	61.7023	13.53	Yes	Yes	1	6	8
14	6x44	6x48	58.1535	4.68	Yes	Yes	1	9	8
15	3x43	6x44	100	3.65	No	Yes	0	8	9
16	3x43	6x41	99.2152	7.45	No	No	0	8	7
17	5x54	6x41	98.4074	4.56	No	No	0	7	7
18	3x47	5x54	93.8661	6.13	Yes	No	5	9	7
19	3x47	5x58	86.9763	10.17	Yes	Yes	0	9	8
20	5x58	6x37	84.045	4.84	Yes	No	0	8	7
21	3x46	6x37	82.9429	8.83	No	No	0	8	7
22	2x39	3x46	70.3058	4.56	Yes	No	0	7	8
23	2x39	Allo3	56.607	15.17	Yes	Yes	2	7	0
24	6x51	7x38	46.5609	12.91	Yes	Yes	0	6	5
25	3x32	6x51	41.6734	8.94	Yes	Yes	1	6	6
26	7x45	7x46	27.79	5.57	Yes	Yes	1	9	8
27	6x44	7x45	37.9631	13.9	Yes	Yes	1	9	9
28	3x39	6x44	34.7721	4.52	No	Yes	0	9	9
29	3x38	3x39	33.3064	3.71	No	No	0	6	9
30	3x38	4x50	30.3405	8.65	No	Yes	0	6	9
31	2x45	4x50	18.015	7.91	No	Yes	0	9	9
32	2x45	4x46	16.4166	11.02	No	No	0	9	7
33	4x43	4x46	14.8125	6.47	No	No	0	3	7
34	2x41	4x43	11.5695	3	No	No	0	5	3
35	1x57	2x41	10.0692	6.24	Yes	No	0	7	5
36	2x42	3x46	12.487	6.04	Yes	No	0	7	8
37	2x39	3x49	11.8927	7.23	Yes	No	0	7	8
38	2x60	7x38	37.2245	5.79	Yes	Yes	0	6	5
39	2x60	E1x50	25.1991	5.62	Yes	Yes	0	6	9
40	6x51	6x52	17.4264	5.81	Yes	Yes	1	6	8
41	3x36	6x52	20.577	12.08	Yes	Yes	1	7	8
42	3x36	3x40	20.7271	4.98	Yes	Yes	1	7	7
43	3x40	5x50	46.5493	6.71	Yes	No	0	7	9
44	3x41	5x50	45.2856	16.21	Yes	No	0	5	9
45	3x41	4x52	46.8609	9.11	Yes	No	0	5	4
46	3x49	3x50	10.8944	15.48	No	No	0	8	9
47	3x50	Allo3	11.2983	11.81	No	Yes	0	9	0
48	3x50	3x53	17.4207	5.53	No	No	0	9	8
49	4x52	4x56	45.401	2.77	No	No	0	4	5
50	4x56	5x43	37.9284	2.66	No	Yes	0	5	5
51	5x40	5x43	25.3722	8.96	No	Yes	0	5	5
52	4x64	5x40	11.7946	4.51	No	No	6	4	5
53	4x64	E2.I213	10.5193	4.84	No	No	0	4	4
54	5x36	5x40	11.9504	15.23	Yes	No	6	4	5
55	3x53	3x54	14.5355	1.62	No	Yes	0	8	8
56	3x54	5x65	13.2198	2.85	Yes	No	0	8	8
57	6x34	Allo3	19.5326	4.08	Yes	Yes	0	5	0
58	6x30	6x34	10.4212	1.25	No	Yes	0	6	5
59	6x51	7x34	10.5078	6.95	Yes	No	0	6	4
60	1x35	1x36	11.0964	1.64	No	Yes	0	6	6
61	3x40	6x44	37.4264	6.22	Yes	Yes	1	7	9
62	2x53	7x42	10.3116	5.59	Yes	Yes	1	6	7

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
1x53	7x53	5.05	0	No	Yes	9	9	2	1
1x56	8x50	7.78	2	No	Yes	6	8	1	1
1x56	8x54	4.42	2	No	Yes	6	6	1	2
1x56	Allo3	4.21	2	No	Yes	6	0	1	0
1x60	I1x50	3.65	0	No	No	5	7	2	2
1x60	8x53	21.5	0	No	No	5	5	2	1
8x49	I1x50	4.23	2	Yes	No	7	7	1	2
2x37	2x39	4.71	2	No	Yes	7	7	1	1
2x37	2x40	13.01	2	No	No	7	8	1	1
2x37	Allo3	14.33	2	No	Yes	7	0	1	0
2x39	3x46	4.56	2	Yes	No	7	8	1	2
2x39	3x49	7.23	2	Yes	No	7	8	1	2
2x39	Allo3	15.17	2	Yes	Yes	7	0	1	0
2x40	8x49	8.3	2	No	Yes	8	7	1	1
2x40	Allo3	25.61	2	No	Yes	8	0	1	0
2x43	7x53	11.72	2	No	Yes	7	9	1	1
2x43	Allo3	7.91	2	No	Yes	7	0	1	0
3x49	3x50	15.48	0	No	No	8	9	2	1
3x50	3x53	5.53	0	No	No	9	8	1	2
3x50	Allo3	11.81	0	No	Yes	9	0	1	0
6x34	6x36	7.68	0	Yes	No	5	7	1	2
6x34	Allo3	4.08	0	Yes	Yes	5	0	1	0
7x53	8x50	4.13	2	Yes	Yes	9	8	1	1
7x53	Allo3	6.03	2	Yes	Yes	9	0	1	0
8x49	8x53	11.06	2	Yes	No	7	5	1	1
8x49	Allo3	22.57	2	Yes	Yes	7	0	1	0
8x50	8x54	7.31	2	Yes	Yes	8	6	1	2
8x50	Allo3	4.18	2	Yes	Yes	8	0	1	0
8x53	Allo3	4.66	2	No	Yes	5	0	1	0
6x34	8x48	3.07	0	Yes	No	5	5	1	2
7x54	8x50	2.77	0	No	Yes	7	8	2	1
6x30	6x34	1.25	0	No	Yes	6	5	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
100.00	Single	6QZH	HY-133073; Na	6QZH-CCR7-HY-133073; Na
53.33	Single	6LFL	PubChem 153466996	6LFL-CXCR2-PubChem 153466996
47.06	Single	5LWE	Vercirnon	5LWE-CCR9-Vercirnon
47.06	Consensus	ccr9_off_allo	Other Ligand	5LWE-CCR9-Vercirnon
35.71	Single	5T1A	PubChem 68764898; PubChem 12093170	5T1A-CCR2-PubChem 68764898; PubChem 12093170
33.33	Consensus	ccr2_off_allo	Other Ligand	5T1A-CCR2-PubChem 68764898; PubChem 12093170 6GPX-CCR2-MK0812
23.53	Single	5X7D	PubChem 129318963	5X7D-β₂-(S)-Carazolol-PubChem 129318963
22.22	Single	3VG9	Antibody	3VG9-A_2A-ZM241385-Antibody
21.05	Single	8FN0	PubChem 118610427	8FN0-NTS₁-Neurotensin/neuromedin N-PubChem 118610427-chim(NtGi1-Go)/&β;1/&γ;2
21.05	Single	8JPC	PubChem 118610427; GDP; Mg	8JPC-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
20.69	Single	3VGA	Antibody	3VGA-A_2A-ZM241385-Antibody
20.00	Single	8JPB	PubChem 118610427; GDP; Mg	8JPB-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
17.65	Consensus	nts1_on_allo	Other Ligand	8JPB-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
15.79	Single	8JPF	PubChem 118610427	8JPF-NTS₁-Neurotensin-PubChem 118610427
15.79	Single	8JR9	PCO371	8JR9-PTH1-PCO371-chim(NtGi1-Gs)/&β;1/&γ;2
15.00	Single	8GW8	KHF	8GW8-PTH1-KHF-Gs/&β;1/&γ;2
9.52	Consensus	ffa3_on_allo	Other Ligand	8J20-FFA3-Valeric acid-AR420626-Gi1/&β;1/&γ;2
9.09	Single	8J20	AR420626	8J20-FFA3-Valeric acid-AR420626-Gi1/&β;1/&γ;2
8.70	Single	8TB7	PubChem 168510218	8TB7-GPR61-PubChem 168510218
8.33	Single	7EVM	PubChem 156022738	7EVM-GLP-1-PubChem 156022738-Gs/&β;1/&γ;2
7.14	Single	4PXF	Octyl Beta-D-Glucopyranoside	4PXF-Rhodopsin-Octyl Beta-D-Glucopyranoside-Arrestin1_Finger_loop
7.14	Single	7DUQ	PubChem 156022738	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/&β;1/&γ;2
5.00	Single	7EJX	(1R;2R)-2-PCCA	7EJX-GPR88-(1R;2R)-2-PCCA-Gi1/&β;1/&γ;2
4.55	Single	5XF1	NNC0640	5XF1-Glucagon-NNC0640
4.17	Single	8JD5	BQI; HZE; PEF	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/&β;1/&γ;2
4.00	Single	8JD3	HZR; PEF	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/&β;1/&γ;2
3.85	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
3.57	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2

Consensus Members
	Id	Members
	6QZH	6QZH-CCR7-HY-133073; Na

Net Summary
I_min	3.65
Number of Linked Nodes	251
Number of Links	276
Number of Hubs	44
Number of Links mediated by Hubs	159
Number of Communities	6
Number of Nodes involved in Communities	42
Number of Links involved in Communities	59

Path Summary
Number Of Nodes in MetaPath	63
Number Of Links MetaPath	62
Number of Shortest Paths	38879
Length Of Smallest Path	3
Average Path Length	13.2422
Length of Longest Path	28
Minimum Path Strength	1.365
Average Path Strength	6.83525
Maximum Path Strength	18.87
Minimum Path Correlation	0.7
Average Path Correlation	0.925731
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	4.16667
Average % Of Corr. Nodes	52.7708
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	50.9758
Maximum Path Hubs %	100

Details about the values in these tables can be found in the corresponding documentation page .

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download ccr7_off_allo.zip

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You can also read or download a guide explaining the meaning of all files and numerical data.