Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index Hub Avg Int. Strength Num Of Links Community ConSurf
1L:L:D1 8.6075400
2L:L:R5 7.135420
3L:L:H6 5.57440
4R:R:P29 3.5405
5R:R:L33 5.3825407
6R:R:N44 5.9725459
7R:R:G52 3.22404
8R:R:M55 4.315415
9R:R:Y64 4.08418
10R:R:D71 6.3975459
11R:R:F74 7.75637
12R:R:E89 4.962504
13R:R:W91 9.415629
14R:R:F93 5.69333607
15R:R:H102 7.9125426
16R:R:D106 7.8675405
17R:R:F110 8.52407
18R:R:V113 5.47407
19R:R:I116 8.75408
20R:R:I119 5.115419
21R:R:A120 3.5725419
22R:R:R123 7.5375419
23R:R:L128 4.215407
24R:R:R137 9.9375407
25R:R:F163 11.5625495
26R:R:L164 5.4775425
27R:R:Y175 5.855473
28R:R:N179 4.2625403
29R:R:F180 6.2375496
30R:R:F210 7.6465109
31R:R:Y221 5.06857718
32R:R:K227 5.195405
33R:R:R238 2.6475407
34R:R:V246 3.7275418
35R:R:F250 6.665489
36R:R:W254 8.08489
37R:R:F255 9.2175406
38R:R:L268 4.815443
39R:R:M271 2.5175401
40R:R:F292 7.404537
41R:R:N294 6.11589
42R:R:Y302 7.552519
43R:R:F309 7.968518
   

Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index Node1 Node2 Recurrence Int. Strength Hub1? Hub2? Community ConSurf1 ConSurf2
1R:R:Q258 R:R:R205 29.81528.18NoNo085
2R:R:R201 R:R:R205 29.49695.33NoNo055
3L:L:R5 R:R:R201 27.65914.26YesNo005
4L:L:E3 L:L:R5 41.3458.14NoYes000
5L:L:D1 R:R:V113 16.00110.22YesYes007
6R:R:V113 R:R:W254 16.544.9YesYes079
7L:L:E3 R:R:F292 41.10114.66NoYes007
8R:R:F292 R:R:L33 29.43536.09YesYes077
9R:R:L33 R:R:M85 40.20534.24YesNo076
10R:R:M85 R:R:N285 36.9794.21NoNo064
11L:L:I41 R:R:N285 29.353214.16NoNo004
12L:L:I41 R:R:V284 28.23156.14NoNo005
13L:L:F4 R:R:V284 27.10477.87NoNo005
14L:L:F4 L:L:H6 25.96776.79NoYes000
15L:L:D1 R:R:F110 12.7498.36YesYes007
16R:R:D106 R:R:F110 10.8479.55YesYes057
17R:R:D106 R:R:V160 10.03344.38YesNo054
18R:R:L164 R:R:V160 10.07194.47YesNo054
19L:L:R5 R:R:H102 52.217711.28YesYes206
20L:L:H6 R:R:L268 13.18533.86YesYes403
21R:R:H102 R:R:W91 47.93385.29YesYes269
22R:R:F93 R:R:W91 48.449713.03YesYes079
23R:R:F93 R:R:P92 53.75774.33YesNo073
24R:R:M87 R:R:P92 52.01493.35NoNo043
25R:R:K90 R:R:M87 50.300310.08NoNo044
26R:R:K90 R:R:Y175 46.86869.55NoYes743
27R:R:E89 R:R:Y175 39.98974.49YesYes043
28R:R:E89 R:R:T177 31.30132.82YesNo043
29L:L:D7 R:R:T177 29.494410.12NoNo003
30L:L:D7 L:L:Y10 27.831111.49NoNo000
31L:L:Y10 R:R:V167 22.35633.79NoNo001
32R:R:N179 R:R:V167 20.52365.91YesNo031
33R:R:L33 R:R:L78 14.67156.92YesNo078
34R:R:F292 R:R:F74 40.464615YesYes377
35R:R:F74 R:R:L78 15.25156.09YesNo078
36R:R:F250 R:R:W254 12.13313.03YesYes899
37R:R:F250 R:R:I116 39.73566.28YesYes098
38R:R:I116 R:R:L67 72.23565.71YesNo089
39R:R:D71 R:R:L67 76.04728.14YesNo099
40R:R:D71 R:R:N44 25.83166.73YesYes599
41R:R:G40 R:R:N44 14.23773.39NoYes089
42R:R:F72 R:R:N44 11.59917.25NoYes079
43R:R:I116 R:R:Y302 10014.51YesYes089
44R:R:I119 R:R:Y302 31.1736.04YesYes199
45R:R:I119 R:R:Y64 28.98873.63YesYes198
46R:R:V303 R:R:Y64 26.04475.05NoYes178
47R:R:F309 R:R:V303 18.89637.87YesNo187
48R:R:R123 R:R:Y302 29.9827.2YesYes199
49R:R:R123 R:R:Y64 31.43995.14YesYes198
50R:R:F72 R:R:I48 10.44922.51NoNo077
51R:R:T60 R:R:Y64 32.97482.5NoYes078
52R:R:R137 R:R:T60 25.90863.88YesNo077
53R:R:L115 R:R:L67 16.52724.15NoNo089
54R:R:I146 R:R:L115 11.90712.85NoNo078
55R:R:D71 R:R:S295 84.00675.89YesNo099
56R:R:F74 R:R:N108 33.67813.62YesNo078
57R:R:I101 R:R:W91 18.16225.87NoYes059
58R:R:I101 R:R:T77 31.03956.08NoNo057
59R:R:T77 R:R:V104 31.31936.35NoNo075
60R:R:N108 R:R:V104 31.73774.43NoNo085
61R:R:F80 R:R:F93 13.02365.36NoYes067
62R:R:F80 R:R:I101 13.608817.58NoNo065
63R:R:C98 R:R:H102 11.23467.37NoYes296
64R:R:C176 R:R:W91 14.93589.14NoYes299
65R:R:C176 R:R:C98 10.23877.28NoNo299
66R:R:C176 R:R:T166 22.68226.76NoNo095
67R:R:T166 R:R:W95 15.16688.49NoNo054
68R:R:Y221 R:R:Y302 26.05754.96YesYes189
69R:R:A120 R:R:Y221 23.06475.34YesYes198
70R:R:A120 R:R:C220 20.76753.61YesNo097
71R:R:C124 R:R:C220 18.40097.28NoNo087
72R:R:C126 R:R:R137 16.67356.96NoYes087
73R:R:A133 R:R:C126 14.41223.61NoNo058
74R:R:C124 R:R:L128 17.213.17NoYes087
75R:R:K227 R:R:L128 12.38712.82YesYes057
76R:R:A133 R:R:I125 12.02261.62NoNo055
77R:R:A181 R:R:N179 14.98723.13NoYes053
78R:R:A181 R:R:R190 13.13144.15NoNo055
79R:R:P187 R:R:R190 11.27057.21NoNo055
80R:R:I195 R:R:L268 11.01645.71NoYes013
81R:R:F210 R:R:Q258 26.94316.4YesNo098
82R:R:F210 R:R:M214 26.85327.46YesNo096
83R:R:V246 R:R:Y302 15.77265.05YesYes189
84R:R:V242 R:R:V246 13.53181.6NoYes088
85R:R:V242 R:R:V305 12.33321.6NoNo087
86R:R:F74 R:R:S295 84.21976.61YesNo079
87R:R:F250 R:R:M214 28.57033.73YesNo096
Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Links and nodes colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
L:L:D1 R:R:F110 8.36 0 Yes Yes 0 7 0 1
L:L:D1 R:R:V113 10.22 0 Yes Yes 0 7 0 1
L:L:D1 R:R:G209 6.71 0 Yes No 0 6 0 1
L:L:D1 R:R:Q258 9.14 0 Yes No 0 8 0 1
L:L:E3 R:R:L81 10.6 0 No No 0 6 0 1
L:L:E3 R:R:F292 4.66 0 No Yes 0 7 0 1
L:L:F4 R:R:V284 7.87 0 No No 0 5 0 1
L:L:R5 R:R:H102 11.28 2 Yes Yes 0 6 0 1
L:L:R5 R:R:L164 4.86 2 Yes Yes 0 5 0 1
L:L:R5 R:R:R201 4.26 2 Yes No 0 5 0 1
L:L:H6 R:R:L268 3.86 4 Yes Yes 0 3 0 1
L:L:H6 R:R:L272 9 4 Yes No 0 3 0 1
L:L:D7 R:R:T177 10.12 0 No No 0 3 0 1
L:L:S8 R:R:L272 4.5 0 No No 0 3 0 1
L:L:G9 R:R:N179 5.09 0 No Yes 0 3 0 1
L:L:Y10 R:R:V167 3.79 0 No No 0 1 0 1
L:L:V39 R:R:D281 10.22 0 No No 0 4 0 1
L:L:V40 R:R:E89 12.84 0 No Yes 0 4 0 1
L:L:I41 R:R:V284 6.14 0 No No 0 5 0 1
L:L:I41 R:R:N285 14.16 0 No No 0 4 0 1
R:R:N285 R:R:P29 3.26 0 No Yes 4 5 1 2
R:R:L33 R:R:M85 4.24 0 Yes No 7 6 2 2
R:R:F292 R:R:L33 6.09 3 Yes Yes 7 7 1 2
R:R:F74 R:R:V105 7.87 3 Yes No 7 6 2 2
R:R:F74 R:R:L109 7.31 3 Yes No 7 8 2 2
R:R:F292 R:R:F74 15 3 Yes Yes 7 7 1 2
R:R:L81 R:R:V105 5.96 0 No No 6 6 1 2
R:R:M85 R:R:N285 4.21 0 No No 6 4 2 1
R:R:E89 R:R:Y175 4.49 0 Yes Yes 4 3 1 2
R:R:C98 R:R:W91 16.98 2 No Yes 9 9 2 2
R:R:H102 R:R:W91 5.29 2 Yes Yes 6 9 1 2
R:R:C98 R:R:H102 7.37 2 No Yes 9 6 2 1
R:R:H102 R:R:L164 7.71 2 Yes Yes 6 5 1 1
R:R:D106 R:R:F110 9.55 0 Yes Yes 5 7 1 1
R:R:D106 R:R:T157 14.45 0 Yes No 5 7 1 2
R:R:D106 R:R:V160 4.38 0 Yes No 5 4 1 2
R:R:F292 R:R:L109 7.31 3 Yes No 7 8 1 2
R:R:F110 R:R:F114 6.43 0 Yes No 7 6 1 2
R:R:F110 R:R:L156 9.74 0 Yes No 7 5 1 2
R:R:P213 R:R:V113 3.53 0 No Yes 9 7 2 1
R:R:V113 R:R:W254 4.9 0 Yes Yes 7 9 1 2
R:R:L164 R:R:V160 4.47 2 Yes No 5 4 1 2
R:R:F178 R:R:L164 4.87 0 No Yes 4 5 2 1
R:R:N179 R:R:V167 5.91 0 Yes No 3 1 1 1
R:R:F178 R:R:R201 7.48 0 No No 4 5 2 1
R:R:I195 R:R:L268 5.71 0 No Yes 1 3 2 1
R:R:L198 R:R:L268 5.54 0 No Yes 4 3 2 1
R:R:R201 R:R:R205 5.33 0 No No 5 5 1 2
R:R:Q258 R:R:R205 8.18 0 No No 8 5 1 2
R:R:F210 R:R:Q258 16.4 10 Yes No 9 8 2 1
R:R:L268 R:R:L272 4.15 4 Yes No 3 3 1 1
R:R:D281 R:R:K278 5.53 0 No No 4 1 1 2
R:R:F292 R:R:S288 3.96 3 Yes No 7 6 1 2
R:R:S112 R:R:V113 3.23 0 No Yes 9 7 2 1
R:R:A181 R:R:N179 3.13 0 No Yes 5 3 2 1
L:L:A2 R:R:D106 3.09 0 No Yes 0 5 0 1
L:L:A42 R:R:E89 3.02 0 No Yes 0 4 0 1
R:R:N179 R:R:T165 2.92 0 Yes No 3 4 1 2
R:R:I280 R:R:M271 2.92 0 No Yes 4 1 2 1
R:R:E89 R:R:T177 2.82 0 Yes No 4 3 1 1
R:R:D281 R:R:M271 2.77 0 No Yes 4 1 1 1
L:L:H6 R:R:M271 2.63 4 Yes Yes 0 1 0 1
R:R:G264 R:R:M271 1.75 0 No Yes 4 1 2 1
R:R:E89 R:R:G88 1.64 0 Yes No 4 3 1 2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB 7WVY_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.
Net Summary
Imin 3.26
Number of Linked Nodes 298
Number of Links 324
Number of Hubs 43
Number of Links mediated by Hubs 153
Number of Communities 11
Number of Nodes involved in Communities 46
Number of Links involved in Communities 54
Path Summary
Number Of Nodes in MetaPath 88
Number Of Links MetaPath 87
Number of Shortest Paths 78762
Length Of Smallest Path 3
Average Path Length 16.3928
Length of Longest Path 41
Minimum Path Strength 1.19
Average Path Strength 6.59784
Maximum Path Strength 25.865
Minimum Path Correlation 0.7
Average Path Correlation 0.932598
Maximum Path Correlation 1
Minimum % Of Corr. Nodes 4
Average % Of Corr. Nodes 45.9139
Maximum % Of Corr. Nodes 100
Minimum Path Hubs % 0
Average Path Hubs % 44.2751
Maximum Path Hubs % 100
AnnotationTypeLinks
Gene OntologyMolecular Function• binding   • tetrapyrrole binding   • heme binding   • electron transfer activity   • cation binding   • transition metal ion binding   • iron ion binding   • ion binding   • metal ion binding   • small molecule binding   • molecular transducer activity   • signaling receptor activity   • amide binding   • amyloid-beta binding   • peptide binding   • G protein-coupled receptor activity   • transmembrane signaling receptor activity   • complement receptor activity   • immune receptor activity   • cargo receptor activity   • RAGE receptor binding   • protein binding   • signaling receptor binding   • scavenger receptor binding   • peptide receptor activity   • N-formyl peptide receptor activity   • G protein-coupled peptide receptor activity   • electron transport chain   • metabolic process   • cellular process   • generation of precursor metabolites and energy   • positive regulation of cytosolic calcium ion concentration   • biological regulation   • regulation of biological quality   • regulation of biological process   • regulation of cellular process   • reactive oxygen species metabolic process   • positive regulation of biological process   • regulation of superoxide metabolic process   • positive regulation of reactive oxygen species metabolic process   • superoxide metabolic process
Gene OntologyBiological Process• electron transport chain   • metabolic process   • cellular process   • generation of precursor metabolites and energy   • positive regulation of cytosolic calcium ion concentration   • biological regulation   • regulation of biological quality   • regulation of biological process   • regulation of cellular process   • reactive oxygen species metabolic process   • positive regulation of biological process   • regulation of superoxide metabolic process   • positive regulation of reactive oxygen species metabolic process   • superoxide metabolic process   • positive regulation of metabolic process   • superoxide anion generation   • positive regulation of superoxide anion generation   • regulation of superoxide anion generation   • regulation of metabolic process   • regulation of reactive oxygen species metabolic process   • positive regulation of cellular process   • cellular response to stimulus   • positive regulation of cell communication   • positive regulation of signal transduction   • response to stimulus   • signaling   • regulation of signal transduction   • intracellular signal transduction   • cell communication   • positive regulation of response to stimulus   • positive regulation of ERK1 and ERK2 cascade   • regulation of intracellular signal transduction   • intracellular signaling cassette   • signal transduction   • regulation of signaling   • positive regulation of MAPK cascade   • positive regulation of intracellular signal transduction   • regulation of MAPK cascade   • regulation of response to stimulus   • MAPK cascade   • regulation of cell communication   • ERK1 and ERK2 cascade   • regulation of ERK1 and ERK2 cascade   • positive regulation of signaling   • immune response-regulating cell surface receptor signaling pathway   • complement receptor mediated signaling pathway   • immune response-activating signaling pathway   • immune response-regulating signaling pathway   • positive regulation of immune response   • regulation of immune system process   • positive regulation of immune system process   • cell surface receptor signaling pathway   • immune response-activating cell surface receptor signaling pathway   • immune response   • immune system process   • regulation of immune response   • activation of immune response   • regulation of defense response   • regulation of response to external stimulus   • negative regulation of inflammatory response   • defense response   • negative regulation of response to stimulus   • negative regulation of biological process   • response to external stimulus   • regulation of inflammatory response   • response to stress   • negative regulation of response to external stimulus   • regulation of response to stress   • negative regulation of defense response   • inflammatory response   • positive chemotaxis   • chemotaxis   • taxis   • response to chemical   • locomotion   • regulation of localization   • import into cell   • positive regulation of cellular component organization   • regulation of cellular component organization   • transport   • vesicle-mediated transport   • cellular component organization   • localization   • positive regulation of endocytosis   • phagocytosis   • cellular component organization or biogenesis   • regulation of endocytosis   • regulation of transport   • regulation of phagocytosis   • regulation of vesicle-mediated transport   • establishment of localization   • positive regulation of phagocytosis   • positive regulation of transport   • endocytosis   • regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction   • positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction   • phosphatidylinositol 3-kinase/protein kinase B signal transduction   • calcium-mediated signaling   • defense response to bacterium   • biological process involved in interspecies interaction between organisms   • response to other organism   • response to bacterium   • response to external biotic stimulus   • response to biotic stimulus   • neuron apoptotic process   • negative regulation of neuron apoptotic process   • negative regulation of programmed cell death   • regulation of apoptotic process   • regulation of programmed cell death   • cell death   • negative regulation of apoptotic process   • negative regulation of cellular process   • apoptotic process   • programmed cell death   • regulation of neuron apoptotic process   • multicellular organismal process   • cellular developmental process   • astrocyte differentiation   • cell development   • astrocyte activation   • glial cell development   • multicellular organism development   • neurogenesis   • astrocyte development   • gliogenesis   • cell differentiation   • anatomical structure development   • system development   • developmental process   • cell activation   • nervous system development   • central nervous system development   • glial cell differentiation   • glial cell activation   • neuroinflammatory response   • positive regulation of monocyte chemotaxis   • positive regulation of locomotion   • regulation of cell motility   • positive regulation of chemotaxis   • positive regulation of cell migration   • regulation of monocyte chemotaxis   • positive regulation of response to external stimulus   • positive regulation of cell motility   • regulation of cell migration   • myeloid leukocyte migration   • positive regulation of mononuclear cell migration   • cell migration   • cell motility   • regulation of mononuclear cell migration   • cell chemotaxis   • regulation of leukocyte chemotaxis   • regulation of leukocyte migration   • positive regulation of leukocyte migration   • positive regulation of leukocyte chemotaxis   • regulation of chemotaxis   • monocyte chemotaxis   • leukocyte migration   • cellular response to chemical stimulus   • regulation of locomotion   • mononuclear cell migration   • leukocyte chemotaxis   • phospholipase C-activating G protein-coupled receptor signaling pathway   • G protein-coupled receptor signaling pathway   • cell adhesion   • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway   • adenylate cyclase-modulating G protein-coupled receptor signaling pathway   • positive regulation of response to biotic stimulus   • regulation of response to biotic stimulus   • innate immune response   • positive regulation of innate immune response   • regulation of innate immune response   • defense response to symbiont   • defense response to other organism   • positive regulation of defense response   • cellular response to nitrogen compound   • response to oxygen-containing compound   • response to nitrogen compound   • cellular response to amyloid-beta   • cellular response to oxygen-containing compound   • response to amyloid-beta   • myeloid leukocyte activation   • leukocyte activation   • macrophage activation   • leukocyte activation involved in inflammatory response   • microglial cell activation   • receptor-mediated endocytosis   • cellular anatomical structure   • periplasmic space   • membrane-bounded organelle   • intracellular anatomical structure   • tertiary granule membrane   • membrane   • intracellular vesicle   • intracellular membrane-bounded organelle   • endomembrane system   • tertiary granule   • intracellular organelle   • cytoplasmic vesicle membrane   • bounding membrane of organelle   • vesicle membrane
Gene OntologyCellular Component• cellular anatomical structure   • periplasmic space   • membrane-bounded organelle   • intracellular anatomical structure   • tertiary granule membrane   • membrane   • intracellular vesicle   • intracellular membrane-bounded organelle   • endomembrane system   • tertiary granule   • intracellular organelle   • cytoplasmic vesicle membrane   • bounding membrane of organelle   • vesicle membrane   • cytoplasmic vesicle   • organelle   • secretory granule   • secretory vesicle   • cytoplasm   • vesicle   • organelle membrane   • secretory granule membrane   • specific granule membrane   • specific granule   • cell periphery   • plasma membrane   • ficolin-1-rich granule membrane   • ficolin-1-rich granule   • protein binding   • binding   • enzyme binding   • GTPase binding   • protein-containing complex binding   • pyrophosphatase activity   • GTPase activity   • ribonucleoside triphosphate phosphatase activity   • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides   • hydrolase activity   • hydrolase activity, acting on acid anhydrides   • catalytic activity   • signaling receptor complex adaptor activity   • protein-macromolecule adaptor activity   • molecular adaptor activity   • signaling adaptor activity   • multicellular organismal process   • system process   • sensory perception of chemical stimulus   • sensory perception   • nervous system process   • sensory perception of taste   • developmental process   • sensory organ development   • eye development   • animal organ development   • retina development in camera-type eye   • visual system development   • multicellular organism development   • camera-type eye development   • anatomical structure development   • sensory system development   • system development   • cell population proliferation   • cellular process   • cellular response to stimulus   • regulation of biological process   • regulation of cellular process   • response to stimulus   • signaling   • biological regulation   • signal transduction   • cell communication   • response to ketone   • response to prostaglandin   • response to lipid   • response to endogenous stimulus   • response to alcohol   • cellular response to prostaglandin stimulus   • response to oxygen-containing compound   • cellular response to oxygen-containing compound   • cellular response to endogenous stimulus   • cellular response to prostaglandin E stimulus   • cellular response to chemical stimulus   • cellular response to alcohol   • response to hormone   • response to chemical   • cellular response to lipid   • response to prostaglandin E   • cellular response to ketone   • cellular response to hormone stimulus   • small GTPase-mediated signal transduction   • Ras protein signal transduction   • intracellular signal transduction   • intracellular signaling cassette   • phospholipase C-activating G protein-coupled receptor signaling pathway   • G protein-coupled receptor signaling pathway   • cellular response to nitrogen compound   • response to dopamine   • cellular response to dopamine   • response to monoamine   • response to catecholamine   • adenylate cyclase-activating dopamine receptor signaling pathway   • cellular response to catecholamine stimulus   • G protein-coupled dopamine receptor signaling pathway   • response to nitrogen compound   • adenylate cyclase-activating G protein-coupled receptor signaling pathway   • cellular response to monoamine stimulus   • adenylate cyclase-modulating G protein-coupled receptor signaling pathway   • synaptic signaling   • cellular response to acetylcholine   • cell-cell signaling   • acetylcholine receptor signaling pathway   • postsynaptic signal transduction   • G protein-coupled acetylcholine receptor signaling pathway   • response to acetylcholine   • protein-containing complex   • extrinsic component of plasma membrane   • catalytic complex   • plasma membrane protein complex   • cytoplasmic side of membrane   • membrane protein complex   • heterotrimeric G-protein complex   • side of membrane   • cytoplasmic side of plasma membrane   • GTPase complex   • extrinsic component of membrane   • extrinsic component of cytoplasmic side of plasma membrane   • extracellular exosome   • extracellular vesicle   • extracellular organelle   • extracellular region   • extracellular space   • extracellular membrane-bounded organelle   • non-motile cilium   • 9+0 non-motile cilium   • cilium   • neuron projection   • photoreceptor disc membrane   • photoreceptor outer segment   • plasma membrane bounded cell projection   • cell projection   • photoreceptor cell cilium   • cytosol   • vacuolar membrane   • lytic vacuole   • vacuole   • lytic vacuole membrane   • lysosomal membrane   • lysosome   • synapse   • cell junction   • G-protein beta-subunit binding   • fibroblast proliferation   • guanyl nucleotide binding   • GTP binding   • nucleotide binding   • guanyl ribonucleotide binding   • purine ribonucleotide binding   • purine ribonucleoside triphosphate binding   • nucleoside phosphate binding   • ion binding   • purine nucleotide binding   • anion binding   • heterocyclic compound binding   • carbohydrate derivative binding   • ribonucleotide binding   • small molecule binding   • G-protein beta/gamma-subunit complex binding   • signaling receptor binding   • G protein-coupled receptor binding   • cation binding   • metal ion binding   • positive regulation of cell population proliferation   • positive regulation of biological process   • positive regulation of neural precursor cell proliferation   • regulation of cell population proliferation   • neural precursor cell proliferation   • positive regulation of cellular process   • regulation of neural precursor cell proliferation   • reactive oxygen species metabolic process   • regulation of superoxide metabolic process   • positive regulation of reactive oxygen species metabolic process   • superoxide metabolic process   • positive regulation of metabolic process   • superoxide anion generation   • metabolic process   • positive regulation of superoxide anion generation   • regulation of superoxide anion generation   • regulation of metabolic process   • regulation of reactive oxygen species metabolic process   • regulation of calcium ion transport   • regulation of localization   • transport   • regulation of transport   • regulation of monoatomic ion transport   • establishment of localization   • metal ion transport   • calcium ion transport   • localization   • monoatomic ion transport   • regulation of metal ion transport   • monoatomic cation transport   • positive regulation of cell communication   • positive regulation of signal transduction   • regulation of signal transduction   • positive regulation of response to stimulus   • positive regulation of ERK1 and ERK2 cascade   • regulation of intracellular signal transduction   • regulation of signaling   • positive regulation of MAPK cascade   • positive regulation of intracellular signal transduction   • regulation of MAPK cascade   • regulation of response to stimulus   • MAPK cascade   • regulation of cell communication   • ERK1 and ERK2 cascade   • regulation of ERK1 and ERK2 cascade   • positive regulation of signaling   • negative regulation of signaling   • negative regulation of biological process   • negative regulation of G protein-coupled receptor signaling pathway   • negative regulation of cell communication   • negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway   • adrenergic receptor signaling pathway   • negative regulation of cellular process   • regulation of G protein-coupled receptor signaling pathway   • adenylate cyclase-activating adrenergic receptor signaling pathway   • negative regulation of response to stimulus   • negative regulation of signal transduction   • negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway   • regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway   • cell division   • regulation of body fluid levels   • renal system process   • positive regulation of urine volume   • regulation of urine volume   • regulation of biological quality   • regulation of vascular associated smooth muscle cell proliferation   • positive regulation of vascular associated smooth muscle cell proliferation   • regulation of smooth muscle cell proliferation   • smooth muscle cell proliferation   • positive regulation of smooth muscle cell proliferation   • muscle cell proliferation   • vascular associated smooth muscle cell proliferation   • gamma-aminobutyric acid signaling pathway   • purinergic nucleotide receptor signaling pathway   • cell surface receptor signaling pathway   • G protein-coupled purinergic receptor signaling pathway   • G protein-coupled adenosine receptor signaling pathway   • regulation of molecular function   • regulation of adenylate cyclase activity   • regulation of catalytic activity   • negative regulation of molecular function   • negative regulation of catalytic activity   • negative regulation of adenylate cyclase activity   • regulated exocytosis   • regulation of calcium ion-dependent exocytosis   • negative regulation of transport   • negative regulation of regulated secretory pathway   • vesicle-mediated transport   • regulation of regulated secretory pathway   • secretion by cell   • regulation of secretion by cell   • negative regulation of secretion   • negative regulation of exocytosis   • negative regulation of secretion by cell   • calcium-ion regulated exocytosis   • secretion   • negative regulation of calcium ion-dependent exocytosis   • export from cell   • regulation of vesicle-mediated transport   • regulation of secretion   • exocytosis   • regulation of exocytosis   • regulation of programmed cell death   • negative regulation of apoptotic signaling pathway   • negative regulation of programmed cell death   • regulation of apoptotic process   • cell death   • apoptotic signaling pathway   • negative regulation of apoptotic process   • apoptotic process   • programmed cell death   • regulation of apoptotic signaling pathway   • positive regulation of locomotion   • regulation of cell motility   • positive regulation of cell migration   • regulation of locomotion   • positive regulation of cell motility   • regulation of cell migration   • cell migration   • cell motility   • locomotion   • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway   • trans-synaptic signaling   • modulation of chemical synaptic transmission   • negative regulation of synaptic transmission   • chemical synaptic transmission   • regulation of trans-synaptic signaling   • anterograde trans-synaptic signaling   • response to nutrient levels   • response to nutrient   • midbody   • dense core granule   • neuronal dense core vesicle   • centrosome   • microtubule organizing center   • cytoskeleton   • membraneless organelle   • intracellular membraneless organelle   • microtubule cytoskeleton   • somatodendritic compartment   • dendrite   • dendritic tree   • nucleus   • membrane-enclosed lumen   • intracellular organelle lumen   • nucleoplasm   • organelle lumen   • nuclear lumen   • neuron to neuron synapse   • hippocampal mossy fiber to CA3 synapse   • cell body   • ciliary basal body   • DNA binding   • nucleic acid binding   • enzyme regulator activity   • enzyme activator activity   • peptidase regulator activity   • molecular function activator activity   • molecular function regulator activity   • peptidase activator activity   • transition metal ion binding   • growth factor receptor binding   • PTB domain binding   • protein domain specific binding   • identical protein binding   • signaling receptor regulator activity   • receptor ligand activity   • signaling receptor activator activity   • molecular function inhibitor activity   • serine-type endopeptidase inhibitor activity   • enzyme inhibitor activity   • peptidase inhibitor activity   • endopeptidase regulator activity   • endopeptidase inhibitor activity   • protein serine/threonine kinase binding   • kinase binding   • protein kinase binding   • heparin binding   • glycosaminoglycan binding   • sulfur compound binding   • negative regulation of long-term synaptic potentiation   • long-term synaptic potentiation   • regulation of synaptic plasticity   • positive regulation of synaptic transmission   • regulation of long-term synaptic potentiation   • regulation of synapse structure or activity   • regulation of postsynaptic membrane potential   • regulation of system process   • chemical synaptic transmission, postsynaptic   • modulation of excitatory postsynaptic potential   • regulation of multicellular organismal process   • regulation of nervous system process   • excitatory postsynaptic potential   • regulation of membrane potential   • regulation of calcium-mediated signaling   • positive regulation of calcium-mediated signaling   • calcium-mediated signaling   • cellular component organization   • extracellular matrix organization   • cellular component organization or biogenesis   • extracellular structure organization   • external encapsulating structure organization   • regulation of multicellular organism growth   • regulation of growth   • regulation of developmental growth   • regulation of developmental process   • developmental growth   • growth   • multicellular organism growth   • axonogenesis   • cellular developmental process   • cell projection organization   • plasma membrane bounded cell projection morphogenesis   • cell development   • neuron projection development   • cell morphogenesis   • neurogenesis   • cell projection morphogenesis   • neuron differentiation   • neuron projection morphogenesis   • cell differentiation   • plasma membrane bounded cell projection organization   • nervous system development   • axon development   • cell morphogenesis involved in neuron differentiation   • generation of neurons   • anatomical structure morphogenesis   • neuron development   • cell growth   • collateral sprouting in absence of injury   • collateral sprouting   • developmental cell growth   • developmental growth involved in morphogenesis   • positive regulation of macromolecule biosynthetic process   • positive regulation of biosynthetic process   • regulation of cytokine production   • cytokine production   • positive regulation of macromolecule metabolic process   • regulation of biosynthetic process   • regulation of macromolecule metabolic process   • gene expression   • macromolecule biosynthetic process   • regulation of chemokine production   • regulation of gene expression   • biosynthetic process   • positive regulation of gene expression   • chemokine production   • positive regulation of chemokine production   • positive regulation of multicellular organismal process   • regulation of macromolecule biosynthetic process   • macromolecule metabolic process   • positive regulation of cytokine production   • astrocyte differentiation   • astrocyte activation   • glial cell development   • astrocyte development   • gliogenesis   • response to stress   • defense response   • cell activation   • central nervous system development   • glial cell differentiation   • glial cell activation   • inflammatory response   • neuroinflammatory response   • Notch signaling pathway   • myeloid leukocyte activation   • leukocyte activation   • macrophage activation   • immune system process   • leukocyte activation involved in inflammatory response   • microglial cell activation   • neuron recognition   • axon choice point recognition   • cell recognition   • axon midline choice point recognition   • axon guidance   • neuron projection guidance   • positive regulation of protein metabolic process   • regulation of protein metabolic process   • primary metabolic process   • regulation of primary metabolic process   • protein metabolic process   • ribonucleotide catabolic process   • pyridine nucleotide catabolic process   • aerobic respiration   • oxoacid metabolic process   • carbohydrate catabolic process   • carbohydrate derivative metabolic process   • organophosphate catabolic process   • regulation of generation of precursor metabolites and energy   • positive regulation of phosphate metabolic process   • nucleoside phosphate catabolic process   • organic acid metabolic process   • regulation of ATP metabolic process   • nucleobase-containing compound metabolic process   • regulation of purine nucleotide catabolic process   • positive regulation of nucleotide catabolic process   • regulation of small molecule metabolic process   • glycolytic process   • regulation of nucleotide metabolic process   • phosphate-containing compound metabolic process   • pyridine-containing compound metabolic process   • small molecule metabolic process   • regulation of nucleobase-containing compound metabolic process   • purine ribonucleotide catabolic process   • phosphorus metabolic process   • nucleoside phosphate metabolic process   • nicotinamide nucleotide metabolic process   • pyruvate metabolic process   • regulation of carbohydrate catabolic process   • positive regulation of phosphorus metabolic process   • purine nucleoside diphosphate metabolic process   • purine-containing compound catabolic process   • nucleotide metabolic process   • regulation of purine nucleotide metabolic process   • nucleobase-containing compound catabolic process   • positive regulation of ATP metabolic process   • nucleoside diphosphate metabolic process   • purine nucleoside diphosphate catabolic process   • nucleoside diphosphate catabolic process   • regulation of phosphorus metabolic process   • regulation of nucleotide catabolic process   • positive regulation of carbohydrate metabolic process   • nucleoside triphosphate metabolic process   • monocarboxylic acid metabolic process   • purine ribonucleotide metabolic process   • pyridine-containing compound catabolic process   • ribose phosphate metabolic process   • cellular respiration   • ATP metabolic process   • catabolic process   • energy derivation by oxidation of organic compounds   • positive regulation of nucleotide metabolic process   • positive regulation of purine nucleotide catabolic process   • purine nucleotide metabolic process   • ribonucleotide metabolic process   • nucleobase-containing small molecule metabolic process   • purine ribonucleoside triphosphate metabolic process   • ribonucleoside diphosphate metabolic process   • ribonucleoside diphosphate catabolic process   • regulation of carbohydrate metabolic process   • nucleotide catabolic process   • purine nucleoside triphosphate metabolic process   • carbohydrate metabolic process   • purine nucleotide catabolic process   • carbohydrate derivative catabolic process   • positive regulation of glycolytic process   • ADP catabolic process   • carboxylic acid metabolic process   • generation of precursor metabolites and energy   • regulation of catabolic process   • regulation of glycolytic process   • purine-containing compound metabolic process   • positive regulation of purine nucleotide metabolic process   • positive regulation of catabolic process   • ADP metabolic process   • organophosphate metabolic process   • purine ribonucleoside diphosphate metabolic process   • positive regulation of small molecule metabolic process   • purine ribonucleoside diphosphate catabolic process   • myeloid leukocyte differentiation   • mononuclear cell differentiation   • microglia differentiation   • hemopoiesis   • macrophage differentiation   • microglia development   • myeloid cell differentiation   • myeloid cell development   • leukocyte differentiation   • regulation of cellular component organization   • positive regulation of cellular component organization   • positive regulation of amyloid fibril formation   • regulation of amyloid fibril formation   • amyloid fibril formation   • positive regulation of supramolecular fiber organization   • regulation of supramolecular fiber organization   • supramolecular fiber organization   • positive regulation of long-term synaptic potentiation   • cellular localization   • intracellular transport   • axo-dendritic transport   • establishment of localization in cell   • microtubule-based transport   • transport along microtubule   • cytoskeleton-dependent intracellular transport   • microtubule-based movement   • microtubule-based process   • cell junction organization   • synapse organization   • cellular response to metal ion   • response to metal ion   • cellular response to manganese ion   • response to manganese ion   • regulation of Wnt signaling pathway   • Wnt signaling pathway   • response to lead ion   • ligand-gated ion channel signaling pathway   • ionotropic glutamate receptor signaling pathway   • glutamate receptor signaling pathway   • regulation of non-canonical NF-kappaB signal transduction   • non-canonical NF-kappaB signal transduction   • positive regulation of non-canonical NF-kappaB signal transduction   • cell activation involved in immune response   • astrocyte activation involved in immune response   • immune response   • immune effector process   • negative regulation of metabolic process   • negative regulation of gene expression   • negative regulation of biosynthetic process   • negative regulation of macromolecule biosynthetic process   • negative regulation of macromolecule metabolic process   • positive regulation of cell cycle   • mitotic cell cycle   • regulation of mitotic cell cycle   • positive regulation of mitotic cell cycle   • cell cycle   • regulation of cell cycle   • regulation of tumor necrosis factor production   • positive regulation of tumor necrosis factor superfamily cytokine production   • tumor necrosis factor superfamily cytokine production   • positive regulation of tumor necrosis factor production   • tumor necrosis factor production   • regulation of tumor necrosis factor superfamily cytokine production   • neuron projection maintenance   • neuron projection organization   • cellular response to amyloid-beta   • response to amyloid-beta   • behavior   • learning   • learning or memory   • cognition   • regulation of defense response   • regulation of response to external stimulus   • response to external stimulus   • regulation of inflammatory response   • positive regulation of response to external stimulus   • positive regulation of inflammatory response   • regulation of response to stress   • positive regulation of defense response   • inorganic ion homeostasis   • homeostatic process   • intracellular copper ion homeostasis   • copper ion homeostasis   • cellular homeostasis   • chemical homeostasis   • intracellular monoatomic cation homeostasis   • monoatomic ion homeostasis   • intracellular chemical homeostasis   • monoatomic cation homeostasis   • intracellular monoatomic ion homeostasis   • developmental maturation   • neuron remodeling   • anatomical structure maturation   • neuron maturation   • cell maturation   • reproductive process   • multicellular organismal reproductive process   • reproductive behavior   • mating behavior   • translation   • protein biosynthetic process   • post-transcriptional regulation of gene expression   • regulation of translation   • cellular response to growth factor stimulus   • cellular response to nerve growth factor stimulus   • response to nerve growth factor   • response to growth factor   • interleukin-1 production   • regulation of interleukin-1 beta production   • positive regulation of interleukin-1 beta production   • positive regulation of interleukin-1 production   • regulation of interleukin-1 production   • interleukin-1 beta production   • regulation of neuronal synaptic plasticity   • regulation of long-term neuronal synaptic plasticity   • positive regulation of JNK cascade   • JNK cascade   • regulation of JNK cascade   • regulation of lymphocyte migration   • positive regulation of mononuclear cell migration   • regulation of immune system process   • regulation of mononuclear cell migration   • positive regulation of immune system process   • positive regulation of lymphocyte migration   • regulation of leukocyte migration   • positive regulation of T cell migration   • lymphocyte migration   • positive regulation of leukocyte migration   • leukocyte migration   • regulation of T cell migration   • mononuclear cell migration   • T cell migration   • cell adhesion   • NMDA selective glutamate receptor signaling pathway   • positive regulation of DNA-templated transcription   • RNA metabolic process   • RNA biosynthetic process   • nucleic acid biosynthetic process   • DNA-templated transcription   • regulation of RNA metabolic process   • transcription by RNA polymerase II   • regulation of RNA biosynthetic process   • regulation of transcription by RNA polymerase II   • positive regulation of transcription by RNA polymerase II   • nucleobase-containing compound biosynthetic process   • nucleic acid metabolic process   • positive regulation of RNA metabolic process   • positive regulation of RNA biosynthetic process   • regulation of DNA-templated transcription   • locomotory behavior   • response to norepinephrine   • cellular response to norepinephrine stimulus   • adult locomotory behavior   • adult behavior   • interleukin-6 production   • positive regulation of interleukin-6 production   • regulation of interleukin-6 production   • import into cell   • endocytosis   • regulation of presynapse assembly   • cellular component biogenesis   • cellular component assembly   • regulation of presynapse organization   • cell junction assembly   • regulation of synapse assembly   • presynapse organization   • regulation of cellular component biogenesis   • regulation of cell junction assembly   • regulation of synapse organization   • synapse assembly   • presynapse assembly   • spontaneous synaptic transmission   • regulation of spontaneous synaptic transmission   • response to peptide   • response to cytokine   • response to interleukin-1   • response to organophosphorus   • response to purine-containing compound   • response to cAMP   • cellular response to cAMP   • response to light stimulus   • visual learning   • visual behavior   • associative learning   • response to radiation   • response to abiotic stimulus   • response to copper ion   • cellular response to copper ion   • dendrite development   • negative regulation of cell population proliferation   • perikaryon   • neuronal cell body   • axon   • cell leading edge   • growth cone lamellipodium   • growth cone   • distal axon   • site of polarized growth   • lamellipodium   • receptor complex   • endoplasmic reticulum lumen   • endoplasmic reticulum   • endosome   • recycling endosome   • neuron spine   • dendritic spine   • postsynapse   • mitochondrial membrane   • organelle inner membrane   • mitochondrion   • mitochondrial inner membrane   • organelle envelope   • mitochondrial envelope   • glial cell projection   • astrocyte projection   • cell surface   • membrane microdomain   • membrane raft   • main axon   • growth cone filopodium   • actin-based cell projection   • filopodium   • Golgi apparatus subcompartment   • Golgi apparatus   • organelle subcompartment   • trans-Golgi network membrane   • trans-Golgi network   • clathrin-coated pit   • amyloid-beta complex   • organelle envelope lumen   • nuclear envelope lumen   • nuclear envelope   • dendritic shaft   • perinuclear region of cytoplasm   • vesicle lumen   • cytoplasmic vesicle lumen   • secretory granule lumen   • platelet alpha granule   • platelet alpha granule lumen   • Golgi-associated vesicle   • early endosome   • Golgi lumen   • endosome membrane   • early endosome membrane   • endosome lumen
SCOP2Domain Identifier• G protein-coupled receptor-like   • Transducin (heterotrimeric G protein), gamma chain
SCOP2Family Identifier• G protein-coupled receptor-like   • Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations-• Orientations of Proteins in Membranes database (OPM)   • Protein Data Bank of Transmembrane Proteins (PDBTM)   • MemProtMD


Details about the values in these tables can be found in the corresponding documentation page .
PDBsumOpen PDBsum Page
ChainR
ProteinReceptor
UniProtP25090
Sequence
>7WVY_nogp_Chain_R
SAGYTVLRI LPLVVLGVT FVLGVLGNG LVIWVAGFR MTRTVTTIC 
YLNLALADF SFTATLPFL IVSMAMGEK WPFGWFLCK LIHIVVDIN 
LFGSVFLIG FIALDRCIC VLHPVWAQN HRTVSLAMK VIVGPWILA 
LVLTLPVFL FLTTVTIPN GDTYCTFNF ASWGGTPEE RLKVAITML 
TARGIIRFV IGFLLPMSI VAICYGLIA AKIHKKGMI KSSRPLRVL 
TAVVASFFI CWFPFQLVA LLGTVWLKE MLFYGKYKI IDILVNPTS 
SLAFFNSCL NPMLYVFVG QDFRERLIH S


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  




This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
6OMMAPeptideFormylpeptideFPR2-ALXHomo sapiensWKYMVX-Gi1/β1/γ23.172020-02-26doi.org/10.1038/s41467-020-14728-9
6OMM (No Gprot) APeptideFormylpeptideFPR2-ALXHomo sapiensWKYMVX-3.172020-02-26doi.org/10.1038/s41467-020-14728-9
6LW5APeptideFormylpeptideFPR2-ALXHomo sapiensWKYMVm--2.82020-03-25doi.org/10.1038/s41467-020-15009-1
7T6SAPeptideFormylpeptideFPR2-ALXHomo sapiensPubChem 24776341-Gi1/β1/γ232022-03-30doi.org/10.1038/s41467-022-28586-0
7T6S (No Gprot) APeptideFormylpeptideFPR2-ALXHomo sapiensPubChem 24776341-32022-03-30doi.org/10.1038/s41467-022-28586-0
7T6UAPeptideFormylpeptideFPR2-ALXHomo sapiensCGEN-855A-Gi1/β1/γ22.92022-03-30doi.org/10.1038/s41467-022-28586-0
7T6U (No Gprot) APeptideFormylpeptideFPR2-ALXHomo sapiensCGEN-855A-2.92022-03-30doi.org/10.1038/s41467-022-28586-0
7T6VAPeptideFormylpeptideFPR2-ALXHomo sapiensfMLFII-Gi1/β1/γ23.12022-03-30doi.org/10.1038/s41467-022-28586-0
7T6V (No Gprot) APeptideFormylpeptideFPR2-ALXHomo sapiensfMLFII-3.12022-03-30doi.org/10.1038/s41467-022-28586-0
7WVVAPeptideFormylpeptideFPR2-ALXHomo sapiensfMLFII-Gi2/β1/γ22.92022-04-13doi.org/10.1038/s41467-022-29361-x
7WVV (No Gprot) APeptideFormylpeptideFPR2-ALXHomo sapiensfMLFII-2.92022-04-13doi.org/10.1038/s41467-022-29361-x
7WVWAPeptideFormylpeptideFPR2-ALXHomo sapiensfMYFINILTL-Gi2/β1/γ23.12022-04-13doi.org/10.1038/s41467-022-29361-x
7WVW (No Gprot) APeptideFormylpeptideFPR2-ALXHomo sapiensfMYFINILTL-3.12022-04-13doi.org/10.1038/s41467-022-29361-x
7WVXAPeptideFormylpeptideFPR2-ALXHomo sapiensHumanin-Gi2/β1/γ22.82022-04-13doi.org/10.1038/s41467-022-29361-x
7WVX (No Gprot) APeptideFormylpeptideFPR2-ALXHomo sapiensHumanin-2.82022-04-13doi.org/10.1038/s41467-022-29361-x
7WVYAPeptideFormylpeptideFPR2-ALXHomo sapiensAmyloid-β42-Gi2/β1/γ232022-04-13doi.org/10.1038/s41467-022-29361-x
7WVY (No Gprot) APeptideFormylpeptideFPR2-ALXHomo sapiensAmyloid-β42-32022-04-13doi.org/10.1038/s41467-022-29361-x
8Y62APeptideFormylpeptideFPR2-ALXHomo sapiensC16:0 Ceramide-Gi1/β1/γ23.22025-02-05doi.org/10.1126/science.ado4188
8Y62 (No Gprot) APeptideFormylpeptideFPR2-ALXHomo sapiensC16:0 Ceramide-3.22025-02-05doi.org/10.1126/science.ado4188
8Y63APeptideFormylpeptideFPR2-ALXHomo sapiensC20:0 Ceramide-Gi1/β1/γ23.22025-02-05doi.org/10.1126/science.ado4188
8Y63 (No Gprot) APeptideFormylpeptideFPR2-ALXHomo sapiensC20:0 Ceramide-3.22025-02-05doi.org/10.1126/science.ado4188
9JHJAPeptideFormylpeptideFPR2-ALXHomo sapiensC18:0 Ceramide-Gi1/β1/γ23.22025-03-19doi.org/10.1126/science.ado4188
9JHJ (No Gprot) APeptideFormylpeptideFPR2-ALXHomo sapiensC18:0 Ceramide-3.22025-03-19doi.org/10.1126/science.ado4188




You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 7WVY_nogp.zip



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