psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:Y175	7.72	Yes	Yes	0	0	3
2	L:L:?1	R:R:T177	9.71	Yes	No	0	0	3
3	L:L:?1	R:R:F178	4.01	Yes	No	0	0	4
4	L:L:?1	R:R:R205	15.01	Yes	Yes	0	0	5
5	L:L:?1	R:R:F257	4.01	Yes	Yes	0	0	7
6	R:R:L28	R:R:V24	4.47	No	No	0	5	4
7	R:R:P286	R:R:P29	7.79	No	No	0	6	5
8	R:R:I82	R:R:L30	5.71	No	No	0	7	5
9	R:R:S289	R:R:V32	8.08	No	No	0	5	5
10	R:R:L33	R:R:L78	6.92	No	Yes	0	7	8
11	R:R:I82	R:R:L33	8.56	No	No	0	7	7
12	R:R:F292	R:R:L33	6.09	Yes	No	0	7	7
13	R:R:F37	R:R:G34	6.02	No	No	0	6	5
14	R:R:L39	R:R:V35	5.96	No	No	0	5	5
15	R:R:F293	R:R:T36	6.49	Yes	No	1	5	7
16	R:R:C296	R:R:T36	6.76	No	No	1	8	7
17	R:R:F37	R:R:V38	3.93	No	No	0	6	5
18	R:R:F37	R:R:L78	3.65	No	Yes	0	6	8
19	R:R:C296	R:R:L39	4.76	No	No	0	8	5
20	R:R:G40	R:R:T75	5.46	No	No	0	8	7
21	R:R:T75	R:R:V41	7.93	No	No	0	7	6
22	R:R:G43	R:R:L42	3.42	No	No	0	8	4
23	R:R:L42	R:R:L46	5.54	No	No	0	4	6
24	R:R:G43	R:R:P299	4.06	No	No	0	8	9
25	R:R:D71	R:R:N44	5.39	Yes	No	0	9	9
26	R:R:F72	R:R:N44	6.04	No	No	0	7	9
27	R:R:N44	R:R:P299	6.52	No	No	0	9	9
28	R:R:G45	R:R:I48	3.53	No	No	6	4	7
29	R:R:G45	R:R:W49	4.22	No	No	6	4	4
30	R:R:L313	R:R:L46	5.54	No	No	0	6	6
31	R:R:V303	R:R:V47	9.62	No	No	0	7	9
32	R:R:I48	R:R:W49	7.05	No	No	6	7	4
33	R:R:F309	R:R:V50	9.18	Yes	No	0	8	7
34	R:R:L313	R:R:V50	7.45	No	No	0	6	7
35	R:R:A51	R:R:F309	4.16	No	Yes	0	7	8
36	R:R:G52	R:R:L65	3.42	No	No	0	4	5
37	R:R:D308	R:R:M55	5.54	No	Yes	0	6	5
38	R:R:M55	R:R:R312	4.96	Yes	No	0	5	5
39	R:R:I62	R:R:R57	6.26	Yes	No	0	7	6
40	R:R:T58	R:R:T61	4.71	No	No	0	7	7
41	R:R:R137	R:R:V59	20.92	Yes	No	0	7	6
42	R:R:A142	R:R:V59	5.09	No	No	0	7	6
43	R:R:T60	R:R:Y64	7.49	No	Yes	0	7	8
44	R:R:R137	R:R:T60	3.88	Yes	No	0	7	7
45	R:R:A142	R:R:I62	4.87	No	Yes	0	7	7
46	R:R:I62	R:R:M143	5.83	Yes	No	0	7	4
47	R:R:C63	R:R:I119	4.91	No	Yes	0	7	9
48	R:R:I119	R:R:Y64	3.63	Yes	Yes	1	9	8
49	R:R:R123	R:R:Y64	7.2	Yes	Yes	1	9	8
50	R:R:Y302	R:R:Y64	4.96	Yes	Yes	1	9	8
51	R:R:V303	R:R:Y64	7.57	No	Yes	0	7	8
52	R:R:I146	R:R:N66	18.41	No	No	0	7	9
53	R:R:N66	R:R:W150	6.78	No	No	0	9	9
54	R:R:D71	R:R:L67	6.79	Yes	No	5	9	9
55	R:R:L115	R:R:L67	5.54	No	No	0	8	9
56	R:R:L67	R:R:N298	6.87	No	Yes	5	9	9
57	R:R:A70	R:R:W150	3.89	No	No	0	8	9
58	R:R:D71	R:R:S112	8.83	Yes	No	0	9	9
59	R:R:D71	R:R:S295	8.83	Yes	No	0	9	9
60	R:R:D71	R:R:N298	6.73	Yes	Yes	5	9	9
61	R:R:N108	R:R:S73	10.43	No	No	0	8	7
62	R:R:F74	R:R:L78	17.05	Yes	Yes	0	7	8
63	R:R:F74	R:R:V105	5.24	Yes	No	0	7	6
64	R:R:F74	R:R:L109	7.31	Yes	No	2	7	8
65	R:R:F292	R:R:F74	11.79	Yes	Yes	2	7	7
66	R:R:F74	R:R:S295	6.61	Yes	No	0	7	9
67	R:R:L78	R:R:T75	7.37	Yes	No	0	8	7
68	R:R:I101	R:R:T77	9.12	No	No	0	5	7
69	R:R:T77	R:R:V104	7.93	No	No	0	7	5
70	R:R:T77	R:R:V105	7.93	No	No	0	7	6
71	R:R:F80	R:R:W91	6.01	Yes	Yes	8	6	9
72	R:R:F80	R:R:F93	8.57	Yes	No	8	6	7
73	R:R:F80	R:R:I101	23.86	Yes	No	0	6	5
74	R:R:S84	R:R:W91	3.71	No	Yes	0	5	9
75	R:R:M85	R:R:N285	9.82	No	No	0	6	4
76	R:R:M87	R:R:P92	8.39	No	No	0	4	3
77	R:R:G88	R:R:K90	3.49	No	No	0	3	4
78	R:R:D173	R:R:K90	15.21	No	No	3	3	4
79	R:R:K90	R:R:Y175	11.94	No	Yes	3	4	3
80	R:R:P92	R:R:W91	4.05	No	Yes	0	3	9
81	R:R:F93	R:R:W91	20.04	No	Yes	8	7	9
82	R:R:C98	R:R:W91	22.2	No	Yes	0	9	9
83	R:R:F93	R:R:L97	4.87	No	No	0	7	7
84	R:R:K99	R:R:W95	22.05	No	Yes	9	7	4
85	R:R:T165	R:R:W95	3.64	No	Yes	0	4	4
86	R:R:T166	R:R:W95	8.49	No	Yes	9	5	4
87	R:R:F96	R:R:L100	3.65	No	No	0	1	5
88	R:R:C98	R:R:H102	5.9	No	No	0	9	6
89	R:R:C176	R:R:C98	5.46	No	No	0	9	9
90	R:R:K99	R:R:L164	5.64	No	No	0	7	5
91	R:R:K99	R:R:T166	6.01	No	No	9	7	5
92	R:R:H102	R:R:L164	3.86	No	No	0	6	5
93	R:R:F161	R:R:I103	6.28	No	No	0	4	5
94	R:R:N108	R:R:V104	4.43	No	No	0	8	5
95	R:R:D106	R:R:T157	5.78	No	No	0	5	7
96	R:R:D106	R:R:V160	13.15	No	No	10	5	4
97	R:R:D106	R:R:R201	4.76	No	Yes	10	5	5
98	R:R:I107	R:R:N108	5.66	No	No	0	5	8
99	R:R:L109	R:R:W254	6.83	No	Yes	2	8	9
100	R:R:F292	R:R:L109	3.65	Yes	No	2	7	8
101	R:R:F110	R:R:F114	4.29	No	No	0	7	6
102	R:R:F110	R:R:L156	13.4	No	No	0	7	5
103	R:R:P213	R:R:V113	7.07	Yes	No	0	9	7
104	R:R:F114	R:R:L152	6.09	No	No	0	6	4
105	R:R:L115	R:R:P149	4.93	No	No	0	8	7
106	R:R:L115	R:R:W150	3.42	No	No	0	8	9
107	R:R:F250	R:R:I116	8.79	Yes	No	0	9	8
108	R:R:I116	R:R:N298	8.5	No	Yes	0	8	9
109	R:R:I116	R:R:Y302	10.88	No	Yes	0	8	9
110	R:R:G117	R:R:I216	3.53	No	Yes	0	7	6
111	R:R:F118	R:R:V145	3.93	No	No	0	7	5
112	R:R:F118	R:R:I146	5.02	No	No	0	7	7
113	R:R:I119	R:R:R123	5.01	Yes	Yes	1	9	9
114	R:R:I119	R:R:Y302	7.25	Yes	Yes	1	9	9
115	R:R:A120	R:R:Y221	5.34	No	Yes	0	9	8
116	R:R:C126	R:R:D122	4.67	No	No	7	8	8
117	R:R:D122	R:R:R137	10.72	No	Yes	7	8	7
118	R:R:R123	R:R:Y221	16.46	Yes	Yes	1	9	8
119	R:R:R123	R:R:Y302	8.23	Yes	Yes	1	9	9
120	R:R:C124	R:R:C220	7.28	No	No	0	8	7
121	R:R:I125	R:R:W132	7.05	No	Yes	0	5	5
122	R:R:A133	R:R:C126	3.61	No	No	0	5	8
123	R:R:C126	R:R:R137	6.96	No	Yes	7	8	7
124	R:R:I224	R:R:V127	7.68	No	No	0	8	8
125	R:R:L128	R:R:L223	4.15	No	No	0	7	3
126	R:R:K227	R:R:L128	5.64	No	No	0	5	7
127	R:R:H129	R:R:W132	4.23	No	Yes	0	6	5
128	R:R:H136	R:R:W132	14.81	No	Yes	0	3	5
129	R:R:H136	R:R:N135	7.65	No	No	0	3	4
130	R:R:S140	R:R:T138	6.4	No	No	0	4	6
131	R:R:G148	R:R:P149	4.06	No	No	0	3	7
132	R:R:I204	R:R:L156	12.85	No	No	0	4	5
133	R:R:L158	R:R:L162	11.07	No	No	0	4	5
134	R:R:R201	R:R:V160	5.23	Yes	No	10	5	4
135	R:R:F163	R:R:F180	11.79	No	Yes	11	5	6
136	R:R:F163	R:R:W183	7.02	No	No	0	5	4
137	R:R:F163	R:R:M197	3.73	No	No	11	5	1
138	R:R:N179	R:R:V167	4.43	No	No	0	3	1
139	R:R:T168	R:R:T174	9.42	No	No	0	2	5
140	R:R:I169	R:R:P170	6.77	Yes	No	0	1	3
141	R:R:I169	R:R:N171	5.66	Yes	No	0	1	4
142	R:R:D173	R:R:I169	9.8	No	Yes	3	3	1
143	R:R:I169	R:R:Y175	3.63	Yes	Yes	3	1	3
144	R:R:D173	R:R:Y175	21.84	No	Yes	3	3	3
145	R:R:F178	R:R:L198	3.65	No	No	0	4	4
146	R:R:F178	R:R:R201	6.41	No	Yes	0	4	5
147	R:R:A181	R:R:N179	4.69	No	No	0	5	3
148	R:R:A194	R:R:F180	8.32	No	Yes	0	3	6
149	R:R:F180	R:R:M197	4.98	Yes	No	11	6	1
150	R:R:G185	R:R:R190	4.5	No	No	0	3	5
151	R:R:E189	R:R:T186	8.47	No	No	0	3	6
152	R:R:I195	R:R:K269	5.82	No	No	0	1	4
153	R:R:L268	R:R:T199	5.9	No	No	0	3	3
154	R:R:R201	R:R:R205	7.46	Yes	Yes	0	5	5
155	R:R:Q258	R:R:R205	7.01	Yes	Yes	0	8	5
156	R:R:A261	R:R:R205	5.53	No	Yes	0	5	5
157	R:R:F206	R:R:S211	3.96	No	No	0	6	4
158	R:R:F206	R:R:Q258	5.86	No	Yes	0	6	8
159	R:R:F206	R:R:L262	9.74	No	No	0	6	5
160	R:R:I208	R:R:V207	9.22	No	No	0	5	4
161	R:R:G209	R:R:P213	4.06	No	Yes	0	6	9
162	R:R:F210	R:R:M214	7.46	Yes	No	4	9	6
163	R:R:F210	R:R:F251	4.29	Yes	No	4	9	6
164	R:R:F210	R:R:F255	9.65	Yes	Yes	4	9	6
165	R:R:F210	R:R:Q258	10.54	Yes	Yes	0	9	8
166	R:R:L212	R:R:P213	4.93	No	Yes	0	5	9
167	R:R:I216	R:R:L212	4.28	Yes	No	0	6	5
168	R:R:F250	R:R:P213	4.33	Yes	Yes	0	9	9
169	R:R:F250	R:R:M214	8.71	Yes	No	0	9	6
170	R:R:F251	R:R:M214	7.46	No	No	4	6	6
171	R:R:I216	R:R:S215	4.64	Yes	No	0	6	3
172	R:R:V217	R:R:V247	4.81	No	No	0	8	8
173	R:R:I224	R:R:Y221	6.04	No	Yes	1	8	8
174	R:R:L243	R:R:Y221	8.21	No	Yes	1	8	8
175	R:R:V246	R:R:Y221	7.57	No	Yes	1	8	8
176	R:R:Y221	R:R:Y302	3.97	Yes	Yes	1	8	9
177	R:R:I224	R:R:L243	8.56	No	No	1	8	8
178	R:R:K231	R:R:M233	4.32	No	No	0	5	3
179	R:R:I234	R:R:L240	4.28	No	No	0	4	5
180	R:R:K235	R:R:S236	6.12	No	No	0	5	6
181	R:R:Q307	R:R:R238	4.67	No	Yes	0	5	7
182	R:R:V242	R:R:V305	6.41	No	No	0	8	7
183	R:R:L301	R:R:V246	7.45	Yes	No	1	8	8
184	R:R:V246	R:R:Y302	5.05	No	Yes	1	8	9
185	R:R:L297	R:R:S249	9.01	No	No	1	6	7
186	R:R:L301	R:R:S249	4.5	Yes	No	1	8	7
187	R:R:F250	R:R:W254	4.01	Yes	Yes	0	9	9
188	R:R:F251	R:R:F255	15	No	Yes	4	6	6
189	R:R:F257	R:R:W254	4.01	Yes	Yes	2	7	9
190	R:R:A291	R:R:W254	5.19	No	Yes	2	8	9
191	R:R:N294	R:R:W254	9.04	No	Yes	0	9	9
192	R:R:F255	R:R:P256	4.33	Yes	No	0	6	9
193	R:R:P256	R:R:T287	5.25	No	No	0	9	7
194	R:R:L290	R:R:P256	4.93	No	No	0	8	9
195	R:R:F257	R:R:Q258	5.86	Yes	Yes	0	7	8
196	R:R:F257	R:R:T287	5.19	Yes	No	0	7	7
197	R:R:F257	R:R:S288	6.61	Yes	No	0	7	6
198	R:R:A291	R:R:F257	5.55	No	Yes	2	8	7
199	R:R:T287	R:R:V260	6.35	No	No	0	7	5
200	R:R:V266	R:R:W267	3.68	No	No	0	4	3
201	R:R:W267	R:R:Y277	17.36	No	No	0	3	3
202	R:R:F273	R:R:K269	7.44	Yes	No	0	5	4
203	R:R:D281	R:R:M271	6.93	No	No	0	4	1
204	R:R:F273	R:R:L272	8.53	Yes	No	0	5	3
205	R:R:F273	R:R:Y274	5.16	Yes	No	0	5	5
206	R:R:I279	R:R:Y277	3.63	No	No	0	3	3
207	R:R:I282	R:R:L283	5.71	No	No	0	2	6
208	R:R:F292	R:R:S288	6.61	Yes	No	0	7	6
209	R:R:C296	R:R:F293	5.59	No	Yes	1	8	5
210	R:R:F293	R:R:L297	6.09	Yes	No	1	5	6
211	R:R:N294	R:R:N298	10.9	No	Yes	0	9	9
212	R:R:L297	R:R:L301	4.15	No	Yes	1	6	8
213	R:R:F304	R:R:P299	4.33	No	No	0	7	9
214	R:R:F304	R:R:M300	3.73	No	No	0	7	7
215	R:R:L301	R:R:Y302	5.86	Yes	Yes	1	8	9
216	R:R:F309	R:R:V303	7.87	Yes	No	0	8	7
217	R:R:F304	R:R:F309	7.5	No	Yes	0	7	8
218	R:R:I314	R:R:R310	3.76	No	No	0	3	8
219	R:R:A68	R:R:V47	3.39	No	No	0	8	9
220	R:R:I228	R:R:P239	3.39	No	No	0	8	7
221	R:R:E270	R:R:Y274	3.37	No	No	0	2	5
222	R:R:L25	R:R:P286	3.28	No	No	0	3	6
223	R:R:L158	R:R:P159	3.28	No	No	0	4	8
224	R:R:C253	R:R:I252	3.27	No	No	0	8	6
225	R:R:N285	R:R:P29	3.26	No	No	0	4	5
226	R:R:A153	R:R:I107	3.25	No	No	0	8	5
227	R:R:F53	R:R:R54	3.21	No	No	0	4	4
228	R:R:C220	R:R:L121	3.17	No	No	0	7	7
229	R:R:C124	R:R:L128	3.17	No	No	0	8	7
230	R:R:T177	R:R:V167	3.17	No	No	0	3	1
231	R:R:A86	R:R:L30	3.15	No	No	0	4	5
232	R:R:T199	R:R:T265	3.14	No	No	0	3	4
233	R:R:I62	R:R:V139	3.07	Yes	No	0	7	3
234	R:R:I203	R:R:T265	3.04	No	No	0	4	4
235	L:L:?1	R:R:F110	3.01	Yes	No	0	0	7
236	R:R:M55	R:R:T61	3.01	Yes	No	0	5	7
237	R:R:L81	R:R:S84	3	No	No	0	6	5
238	R:R:L25	R:R:V24	2.98	No	No	0	3	4
239	R:R:L141	R:R:V145	2.98	No	No	0	3	5
240	R:R:L262	R:R:V266	2.98	No	No	0	5	4
241	R:R:I204	R:R:I208	2.94	No	No	0	4	5
242	R:R:I282	R:R:K278	2.91	No	No	0	2	1
243	R:R:F80	R:R:P79	2.89	Yes	No	0	6	8
244	R:R:P239	R:R:R238	2.88	No	Yes	0	7	7
245	R:R:I48	R:R:L65	2.85	No	No	0	7	5
246	R:R:I107	R:R:L154	2.85	No	No	0	5	4
247	R:R:I216	R:R:L121	2.85	Yes	No	0	6	7
248	R:R:I219	R:R:L223	2.85	No	No	0	3	3
249	R:R:I280	R:R:L263	2.85	No	No	0	4	5
250	R:R:L268	R:R:M271	2.83	No	No	0	3	1
251	R:R:C253	R:R:F293	2.79	No	Yes	0	8	5
252	R:R:L25	R:R:L283	2.77	No	No	0	3	6
253	R:R:L259	R:R:L263	2.77	No	No	0	5	5
254	R:R:D281	R:R:K278	2.77	No	No	0	4	1
255	R:R:H229	R:R:I234	2.65	No	No	0	3	4
256	R:R:R54	R:R:S316	2.64	No	No	0	4	5
257	R:R:R312	R:R:S316	2.64	No	No	0	5	5
258	R:R:R312	R:R:V50	2.62	No	No	0	5	7
259	R:R:F180	R:R:V193	2.62	Yes	No	0	6	4
260	R:R:R238	R:R:V305	2.62	Yes	No	0	7	7
261	R:R:D308	R:R:E311	2.6	No	No	0	6	4
262	R:R:E311	R:R:Q307	2.55	No	No	0	4	5
263	R:R:V247	R:R:Y221	2.52	No	Yes	0	8	8
264	R:R:F273	R:R:L191	2.44	Yes	No	0	5	1
265	R:R:F255	R:R:L259	2.44	Yes	No	0	6	5
266	R:R:L65	R:R:R57	2.43	No	No	0	5	6
267	R:R:F96	R:R:W95	2	No	Yes	0	1	4
268	R:R:A70	R:R:G111	1.95	No	No	0	8	7
269	R:R:A225	R:R:G222	1.95	No	No	0	5	3
270	R:R:G306	R:R:V305	1.84	No	No	0	8	7
271	R:R:G172	R:R:T168	1.82	No	No	0	4	2
272	R:R:P29	R:R:S289	1.78	No	No	0	5	5
273	R:R:G148	R:R:I151	1.76	No	No	0	3	3
274	R:R:G172	R:R:I169	1.76	No	Yes	0	4	1
275	R:R:G264	R:R:I280	1.76	No	No	0	4	4
276	R:R:P187	R:R:T186	1.75	No	No	0	5	6
277	R:R:G232	R:R:M233	1.75	No	No	0	4	3
278	R:R:G94	R:R:L97	1.71	No	No	0	8	7
279	R:R:I234	R:R:P239	1.69	No	No	0	4	7
280	R:R:E89	R:R:G88	1.64	No	No	0	4	3
281	R:R:S288	R:R:V284	1.62	No	No	0	6	5
282	R:R:A200	R:R:M197	1.61	No	No	0	1	1
283	R:R:V31	R:R:V35	1.6	No	No	0	6	5
284	R:R:T138	R:R:V139	1.59	No	No	0	6	3
285	R:R:T196	R:R:V193	1.59	No	No	0	1	4
286	R:R:A194	R:R:L191	1.58	No	No	0	3	1
287	R:R:A225	R:R:L243	1.58	No	No	0	5	8
288	R:R:A245	R:R:L301	1.58	No	Yes	0	6	8
289	R:R:I27	R:R:V31	1.54	No	No	0	6	6
290	R:R:I82	R:R:V83	1.54	No	No	0	7	5
291	R:R:I146	R:R:V147	1.54	No	No	0	7	4
292	R:R:I151	R:R:V155	1.54	No	No	0	3	4
293	R:R:I203	R:R:V207	1.54	No	No	0	4	4
294	R:R:H129	R:R:P130	1.53	No	No	0	6	8
295	R:R:M55	R:R:T56	1.51	Yes	No	0	5	6
296	R:R:L69	R:R:S73	1.5	No	No	0	6	7
297	R:R:N135	R:R:V131	1.48	No	No	0	4	5
298	R:R:I195	R:R:K192	1.45	No	No	0	1	5
299	R:R:K227	R:R:K230	1.44	No	No	0	5	4
300	R:R:K230	R:R:K231	1.44	No	No	0	4	5
301	R:R:I314	R:R:L313	1.43	No	No	0	3	6
302	R:R:L272	R:R:M271	1.41	No	No	0	3	1
303	R:R:R238	R:R:S236	1.32	Yes	No	0	7	6
304	R:R:A133	R:R:W132	1.3	No	Yes	0	5	5
305	R:R:E188	R:R:E189	1.27	No	No	0	3	3
306	R:R:F180	R:R:R190	1.07	Yes	No	0	6	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:?1	7.245	6	0	0
2	R:R:M55	3.755	4	0	5
3	R:R:I62	5.0075	4	0	7
4	R:R:Y64	6.17	5	1	8
5	R:R:D71	7.314	5	5	9
6	R:R:F74	9.6	5	2	7
7	R:R:L78	8.7475	4	0	8
8	R:R:F80	10.3325	4	8	6
9	R:R:W91	11.202	5	8	9
10	R:R:W95	9.045	4	9	4
11	R:R:I119	5.2	4	1	9
12	R:R:R123	9.225	4	1	9
13	R:R:W132	6.8475	4	0	5
14	R:R:R137	10.62	4	7	7
15	R:R:I169	5.524	5	3	1
16	R:R:Y175	11.2825	4	3	3
17	R:R:F180	5.756	5	11	6
18	R:R:R201	5.965	4	10	5
19	R:R:R205	8.7525	4	0	5
20	R:R:F210	7.985	4	4	9
21	R:R:P213	5.0975	4	0	9
22	R:R:I216	3.825	4	0	6
23	R:R:Y221	7.15857	7	1	8
24	R:R:R238	2.8725	4	0	7
25	R:R:F250	6.46	4	0	9
26	R:R:W254	5.816	5	2	9
27	R:R:F255	7.855	4	4	6
28	R:R:F257	5.205	6	2	7
29	R:R:Q258	7.3175	4	0	8
30	R:R:F273	5.8925	4	0	5
31	R:R:F292	7.035	4	2	7
32	R:R:F293	5.24	4	1	5
33	R:R:N298	8.25	4	5	9
34	R:R:L301	4.708	5	1	8
35	R:R:Y302	6.6	7	1	9
36	R:R:F309	7.1775	4	0	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:F110	70.3128	3.01	Yes	No	0	0	7
2	R:R:F110	R:R:L156	66.093	13.4	No	No	0	7	5
3	R:R:I204	R:R:L156	64.6478	12.85	No	No	0	4	5
4	R:R:I204	R:R:I208	63.1916	2.94	No	No	0	4	5
5	R:R:I208	R:R:V207	61.7243	9.22	No	No	0	5	4
6	R:R:I203	R:R:V207	60.246	1.54	No	No	0	4	4
7	R:R:I203	R:R:T265	58.7567	3.04	No	No	0	4	4
8	R:R:T199	R:R:T265	57.2563	3.14	No	No	0	3	4
9	R:R:L268	R:R:T199	55.7174	5.9	No	No	0	3	3
10	R:R:L268	R:R:M271	54.1949	2.83	No	No	0	3	1
11	R:R:D281	R:R:M271	23.4045	6.93	No	No	0	4	1
12	R:R:D281	R:R:K278	21.6614	2.77	No	No	0	4	1
13	R:R:I282	R:R:K278	19.9073	2.91	No	No	0	2	1
14	R:R:I282	R:R:L283	18.1422	5.71	No	No	0	2	6
15	R:R:L25	R:R:L283	16.366	2.77	No	No	0	3	6
16	R:R:L25	R:R:P286	10.9714	3.28	No	No	0	3	6
17	L:L:?1	R:R:F257	97.253	4.01	Yes	Yes	0	0	7
18	R:R:F257	R:R:S288	31.3751	6.61	Yes	No	0	7	6
19	R:R:F292	R:R:S288	30.0734	6.61	Yes	No	0	7	6
20	R:R:F292	R:R:L33	11.6774	6.09	Yes	No	0	7	7
21	R:R:F257	R:R:W254	88.7528	4.01	Yes	Yes	2	7	9
22	R:R:L109	R:R:W254	44.906	6.83	No	Yes	2	8	9
23	R:R:F74	R:R:L109	41.4088	7.31	Yes	No	2	7	8
24	R:R:F74	R:R:L78	19.7088	17.05	Yes	Yes	0	7	8
25	R:R:F292	R:R:F74	25.5944	11.79	Yes	Yes	2	7	7
26	R:R:F250	R:R:W254	75.7902	4.01	Yes	Yes	0	9	9
27	R:R:F250	R:R:I116	86.2982	8.79	Yes	No	0	9	8
28	R:R:I116	R:R:Y302	100	10.88	No	Yes	0	8	9
29	R:R:L301	R:R:Y302	23.4927	5.86	Yes	Yes	1	8	9
30	R:R:L297	R:R:L301	18.8593	4.15	No	Yes	1	6	8
31	R:R:F293	R:R:L297	17.0721	6.09	Yes	No	1	5	6
32	R:R:N294	R:R:W254	14.4244	9.04	No	Yes	0	9	9
33	R:R:N294	R:R:N298	14.2093	10.9	No	Yes	0	9	9
34	R:R:D71	R:R:N298	21.4739	6.73	Yes	Yes	5	9	9
35	R:R:D71	R:R:N44	22.5385	5.39	Yes	No	0	9	9
36	R:R:N44	R:R:P299	20.5086	6.52	No	No	0	9	9
37	R:R:Y302	R:R:Y64	71.3939	4.96	Yes	Yes	1	9	8
38	R:R:T60	R:R:Y64	44.8894	7.49	No	Yes	0	7	8
39	R:R:R137	R:R:T60	43.2125	3.88	Yes	No	0	7	7
40	R:R:R137	R:R:V59	24.2981	20.92	Yes	No	0	7	6
41	R:R:A142	R:R:V59	22.4999	5.09	No	No	0	7	6
42	R:R:A142	R:R:I62	20.6851	4.87	No	Yes	0	7	7
43	R:R:I62	R:R:R57	11.4457	6.26	Yes	No	0	7	6
44	R:R:V303	R:R:Y64	40.6255	7.57	No	Yes	0	7	8
45	R:R:F309	R:R:V303	36.7864	7.87	Yes	No	0	8	7
46	R:R:F309	R:R:V50	42.7437	9.18	Yes	No	0	8	7
47	R:R:R312	R:R:V50	36.2127	2.62	No	No	0	5	7
48	R:R:M55	R:R:R312	29.9906	4.96	Yes	No	0	5	5
49	R:R:D308	R:R:M55	23.581	5.54	No	Yes	0	6	5
50	R:R:L67	R:R:N298	15.3842	6.87	No	Yes	5	9	9
51	R:R:L115	R:R:L67	21.6945	5.54	No	No	0	8	9
52	R:R:L115	R:R:W150	14.1927	3.42	No	No	0	8	9
53	R:R:F74	R:R:S295	30.3271	6.61	Yes	No	0	7	9
54	R:R:F74	R:R:V105	71.1788	5.24	Yes	No	0	7	6
55	R:R:T77	R:R:V105	68.9448	7.93	No	No	0	7	6
56	R:R:T77	R:R:V104	17.6402	7.93	No	No	0	7	5
57	R:R:N108	R:R:V104	15.1525	4.43	No	No	0	8	5
58	R:R:I101	R:R:T77	50.6757	9.12	No	No	0	5	7
59	R:R:F80	R:R:I101	48.3424	23.86	Yes	No	0	6	5
60	R:R:F80	R:R:W91	36.483	6.01	Yes	Yes	8	6	9
61	L:L:?1	R:R:Y175	19.8632	7.72	Yes	Yes	0	0	3
62	R:R:C98	R:R:W91	24.8497	22.2	No	Yes	0	9	9
63	R:R:C98	R:R:H102	19.9073	5.9	No	No	0	9	6
64	R:R:H102	R:R:L164	17.4362	3.86	No	No	0	6	5
65	R:R:K99	R:R:L164	15.1415	5.64	No	No	0	7	5
66	R:R:K99	R:R:W95	10.1219	22.05	No	Yes	9	7	4
67	L:L:?1	R:R:R205	14.8877	15.01	Yes	Yes	0	0	5
68	R:R:R201	R:R:R205	14.2093	7.46	Yes	Yes	0	5	5
69	R:R:D106	R:R:R201	10.3481	4.76	No	Yes	10	5	5
70	R:R:F250	R:R:P213	28.4682	4.33	Yes	Yes	0	9	9
71	R:R:L212	R:R:P213	23.9506	4.93	No	Yes	0	5	9
72	R:R:I216	R:R:L212	22.4226	4.28	Yes	No	0	6	5
73	R:R:Y221	R:R:Y302	16.0296	3.97	Yes	Yes	1	8	9
74	R:R:C126	R:R:R137	16.9728	6.96	No	Yes	7	8	7
75	R:R:I216	R:R:L121	17.7726	2.85	Yes	No	0	6	7
76	R:R:C220	R:R:L121	16.2006	3.17	No	No	0	7	7
77	R:R:C124	R:R:C220	14.6175	7.28	No	No	0	8	7
78	R:R:A133	R:R:C126	15.1746	3.61	No	No	0	5	8
79	R:R:A133	R:R:W132	13.3157	1.3	No	Yes	0	5	5
80	R:R:C124	R:R:L128	13.0233	3.17	No	No	0	8	7
81	R:R:L272	R:R:M271	31.7888	1.41	No	No	0	3	1
82	R:R:F273	R:R:L272	30.1009	8.53	Yes	No	0	5	3
83	R:R:F273	R:R:L191	19.7363	2.44	Yes	No	0	5	1
84	R:R:A194	R:R:L191	18.1036	1.58	No	No	0	3	1
85	R:R:A194	R:R:F180	16.3109	8.32	No	Yes	0	3	6
86	R:R:I169	R:R:Y175	11.0486	3.63	Yes	Yes	3	1	3
87	R:R:Q258	R:R:R205	17.1217	7.01	Yes	Yes	0	8	5
88	R:R:F257	R:R:Q258	26.5376	5.86	Yes	Yes	0	7	8
89	R:R:F206	R:R:Q258	18.4125	5.86	No	Yes	0	6	8
90	R:R:F206	R:R:L262	13.2054	9.74	No	No	0	6	5
91	R:R:F210	R:R:Q258	17.552	10.54	Yes	Yes	0	9	8
92	R:R:F210	R:R:M214	15.7869	7.46	Yes	No	4	9	6
93	R:R:F250	R:R:M214	23.3273	8.71	Yes	No	0	9	6
94	R:R:F210	R:R:F255	12.7586	9.65	Yes	Yes	4	9	6
95	R:R:F257	R:R:T287	11.3189	5.19	Yes	No	0	7	7
96	R:R:D308	R:R:E311	21.9538	2.6	No	No	0	6	4
97	R:R:E311	R:R:Q307	20.3155	2.55	No	No	0	4	5
98	R:R:Q307	R:R:R238	18.6552	4.67	No	Yes	0	5	7
99	R:R:L262	R:R:V266	10.5852	2.98	No	No	0	5	4
100	R:R:F304	R:R:P299	15.9248	4.33	No	No	0	7	9
101	R:R:F255	R:R:L259	16.6749	2.44	Yes	No	0	6	5
102	R:R:L259	R:R:L263	12.5214	2.77	No	No	0	5	5
103	R:R:D71	R:R:S295	29.5659	8.83	Yes	No	0	9	9
104	R:R:F304	R:R:F309	15.1746	7.5	No	Yes	0	7	8
105	R:R:I116	R:R:N298	24.2098	8.5	No	Yes	0	8	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?1	R:R:Y175	7.72	0	Yes	Yes	0	3	0	1
L:L:?1	R:R:T177	9.71	0	Yes	No	0	3	0	1
L:L:?1	R:R:F178	4.01	0	Yes	No	0	4	0	1
L:L:?1	R:R:R205	15.01	0	Yes	Yes	0	5	0	1
L:L:?1	R:R:F257	4.01	0	Yes	Yes	0	7	0	1
R:R:D173	R:R:K90	15.21	3	No	No	3	4	2	2
R:R:K90	R:R:Y175	11.94	3	No	Yes	4	3	2	1
R:R:F110	R:R:F114	4.29	0	No	No	7	6	1	2
R:R:F110	R:R:L156	13.4	0	No	No	7	5	1	2
R:R:D173	R:R:I169	9.8	3	No	Yes	3	1	2	2
R:R:I169	R:R:Y175	3.63	3	Yes	Yes	1	3	2	1
R:R:D173	R:R:Y175	21.84	3	No	Yes	3	3	2	1
R:R:F178	R:R:L198	3.65	0	No	No	4	4	1	2
R:R:F178	R:R:R201	6.41	0	No	Yes	4	5	1	2
R:R:R201	R:R:R205	7.46	10	Yes	Yes	5	5	2	1
R:R:Q258	R:R:R205	7.01	0	Yes	Yes	8	5	2	1
R:R:A261	R:R:R205	5.53	0	No	Yes	5	5	2	1
R:R:F257	R:R:W254	4.01	2	Yes	Yes	7	9	1	2
R:R:A291	R:R:W254	5.19	2	No	Yes	8	9	2	2
R:R:F257	R:R:Q258	5.86	2	Yes	Yes	7	8	1	2
R:R:F257	R:R:T287	5.19	2	Yes	No	7	7	1	2
R:R:F257	R:R:S288	6.61	2	Yes	No	7	6	1	2
R:R:A291	R:R:F257	5.55	2	No	Yes	8	7	2	1
R:R:T177	R:R:V167	3.17	0	No	No	3	1	1	2
L:L:?1	R:R:F110	3.01	0	Yes	No	0	7	0	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	8Y63_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.42
Number of Linked Nodes	278
Number of Links	306
Number of Hubs	36
Number of Links mediated by Hubs	137
Number of Communities	11
Number of Nodes involved in Communities	49
Number of Links involved in Communities	60

Path Summary
Number Of Nodes in MetaPath	106
Number Of Links MetaPath	105
Number of Shortest Paths	50960
Length Of Smallest Path	3
Average Path Length	14.7014
Length of Longest Path	38
Minimum Path Strength	1.44
Average Path Strength	6.54547
Maximum Path Strength	21.12
Minimum Path Correlation	0.7
Average Path Correlation	0.932123
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	2.77778
Average % Of Corr. Nodes	51.9837
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	38.9429
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain • Ras-like P-loop GTPases • G protein-coupled receptor-like
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain • Ras-like P-loop GTPases • G protein-coupled receptor-like
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	_L_
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	_L_
Name
Synonyms
Identifier
Formula
Molecular Weight
SMILES
PubChem
Formal Charge
Total Atoms
Total Chiral Atoms
Total Bonds
Total Aromatic Bonds


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P25090
Sequence	>8Y63_nogp_Chain_R V L R I L P L V V L G V T F V L G V L G N G L V I W V A G F R M T R T V T T I C Y L N L A L A D F S F T A T L P F L I V S M A M G E K W P F G W F L C K L I H I V V D I N L F G S V F L I G F I A L D R C I C V L H P V W A Q N H R T V S L A M K V I V G P W I L A L V L T L P V F L F L T T V T I P N G D T Y C T F N F A S W G T P E E R L K V A I T M L T A R I I R F V I G F S L P M S I V A I C Y G L I A A K I H K K G M I K S S R P L R V L T A V V A S F F I C W F P F Q L V A L L G T V W L K E M L F Y G Y K I I D I L V N P T S S L A F F N S C L N P M L Y V F V G Q D F R E R L I H S L Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	6OMM	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	WKYMVX	-	Gi1/β1/γ2	3.17	2020-02-26	doi.org/10.1038/s41467-020-14728-9
	6OMM (No Gprot)	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	WKYMVX	-		3.17	2020-02-26	doi.org/10.1038/s41467-020-14728-9
	6LW5	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	WKYMVm	-	-	2.8	2020-03-25	doi.org/10.1038/s41467-020-15009-1
	7T6S	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	TC-FPR 43	-	Gi1/β1/γ2	3	2022-03-30	doi.org/10.1038/s41467-022-28586-0
	7T6S (No Gprot)	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	TC-FPR 43	-		3	2022-03-30	doi.org/10.1038/s41467-022-28586-0
	7T6U	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	CGEN-855A	-	Gi1/β1/γ2	2.9	2022-03-30	doi.org/10.1038/s41467-022-28586-0
	7T6U (No Gprot)	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	CGEN-855A	-		2.9	2022-03-30	doi.org/10.1038/s41467-022-28586-0
	7T6V	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	fMLFII	-	Gi1/β1/γ2	3.1	2022-03-30	doi.org/10.1038/s41467-022-28586-0
	7T6V (No Gprot)	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	fMLFII	-		3.1	2022-03-30	doi.org/10.1038/s41467-022-28586-0
	7WVV	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	fMLFII	-	Gi2/β1/γ2	2.9	2022-04-13	doi.org/10.1038/s41467-022-29361-x
	7WVV (No Gprot)	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	fMLFII	-		2.9	2022-04-13	doi.org/10.1038/s41467-022-29361-x
	7WVW	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	fMYFINILTL	-	Gi2/β1/γ2	3.1	2022-04-13	doi.org/10.1038/s41467-022-29361-x
	7WVW (No Gprot)	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	fMYFINILTL	-		3.1	2022-04-13	doi.org/10.1038/s41467-022-29361-x
	7WVX	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	Humanin	-	Gi2/β1/γ2	2.8	2022-04-13	doi.org/10.1038/s41467-022-29361-x
	7WVX (No Gprot)	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	Humanin	-		2.8	2022-04-13	doi.org/10.1038/s41467-022-29361-x
	7WVY	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	Amyloid-β42	-	Gi2/β1/γ2	3	2022-04-13	doi.org/10.1038/s41467-022-29361-x
	7WVY (No Gprot)	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	Amyloid-β42	-		3	2022-04-13	doi.org/10.1038/s41467-022-29361-x
	8Y62	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	C16:0 Ceramide	-	Gi1/β1/γ2	3.2	2025-02-05	doi.org/10.1126/science.ado4188
	8Y62 (No Gprot)	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	C16:0 Ceramide	-		3.2	2025-02-05	doi.org/10.1126/science.ado4188
	8Y63	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	C20:0 Ceramide	-	Gi1/β1/γ2	3.2	2025-02-05	doi.org/10.1126/science.ado4188
	8Y63 (No Gprot)	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	C20:0 Ceramide	-		3.2	2025-02-05	doi.org/10.1126/science.ado4188
	9JHJ	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	C18:0 Ceramide	-	Gi1/β1/γ2	3.2	2025-03-19	doi.org/10.1126/science.ado4188
	9JHJ (No Gprot)	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	C18:0 Ceramide	-		3.2	2025-03-19	doi.org/10.1126/science.ado4188
	8ZBW	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	Quin-C1	-	Gi2/β1/γ2	2.58	2025-09-10	doi.org/10.1038/s41401-025-01525-7
	8ZBW (No Gprot)	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	Quin-C1	-		2.58	2025-09-10	doi.org/10.1038/s41401-025-01525-7

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

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