psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	L:L:L2	3.77	Yes	No	0	0	0
2	L:L:?1	R:R:D106	14.77	Yes	Yes	2	0	5
3	L:L:?1	R:R:L109	8.79	Yes	No	0	0	8
4	L:L:?1	R:R:F110	16.57	Yes	Yes	2	0	7
5	L:L:?1	R:R:R201	11.02	Yes	Yes	2	0	5
6	L:L:?1	R:R:R205	22.03	Yes	Yes	2	0	5
7	L:L:?1	R:R:W254	6.2	Yes	Yes	0	0	9
8	L:L:?1	R:R:F257	6.63	Yes	No	0	0	7
9	L:L:I4	L:L:L2	4.28	No	No	0	0	0
10	L:L:L2	R:R:V105	5.96	No	No	0	0	6
11	L:L:F3	L:L:I5	7.54	Yes	No	0	0	0
12	L:L:F3	R:R:R205	3.21	Yes	Yes	0	0	5
13	L:L:F3	R:R:G264	4.52	Yes	No	0	0	4
14	L:L:F3	R:R:V284	7.87	Yes	No	0	0	5
15	L:L:I4	R:R:H102	5.3	No	No	0	0	6
16	L:L:I4	R:R:F178	5.02	No	No	0	0	4
17	L:L:I5	R:R:T177	7.6	No	No	0	0	3
18	L:L:I5	R:R:L268	5.71	No	Yes	0	0	3
19	R:R:S19	R:R:Y22	3.82	No	No	0	4	2
20	R:R:R26	R:R:Y22	4.12	No	No	0	4	2
21	R:R:I282	R:R:Y22	4.84	No	No	0	2	2
22	R:R:R26	R:R:T23	3.88	No	No	0	4	2
23	R:R:L28	R:R:P29	3.28	No	No	0	5	5
24	R:R:N285	R:R:P29	13.03	No	No	0	4	5
25	R:R:S289	R:R:V32	6.46	No	No	0	5	5
26	R:R:L33	R:R:L78	4.15	Yes	Yes	3	7	8
27	R:R:I82	R:R:L33	5.71	No	Yes	0	7	7
28	R:R:L33	R:R:M85	4.24	Yes	No	0	7	6
29	R:R:F292	R:R:L33	6.09	Yes	Yes	3	7	7
30	R:R:F293	R:R:T36	3.89	No	No	3	5	7
31	R:R:C296	R:R:T36	8.45	No	No	3	8	7
32	R:R:F37	R:R:V41	5.24	Yes	No	0	6	6
33	R:R:F37	R:R:L78	3.65	Yes	Yes	0	6	8
34	R:R:F37	R:R:P79	10.11	Yes	No	0	6	8
35	R:R:F72	R:R:V41	5.24	No	No	0	7	6
36	R:R:T75	R:R:V41	4.76	No	No	0	7	6
37	R:R:D71	R:R:N44	6.73	Yes	No	1	9	9
38	R:R:F72	R:R:N44	6.04	No	No	0	7	9
39	R:R:N44	R:R:P299	8.15	No	No	1	9	9
40	R:R:L313	R:R:L46	4.15	No	No	0	6	6
41	R:R:A68	R:R:V47	3.39	No	Yes	0	8	9
42	R:R:V303	R:R:V47	11.22	No	Yes	5	7	9
43	R:R:F304	R:R:V47	3.93	No	Yes	0	7	9
44	R:R:F309	R:R:V47	9.18	Yes	Yes	5	8	9
45	R:R:I48	R:R:L65	4.28	Yes	No	0	7	5
46	R:R:A68	R:R:I48	3.25	No	Yes	0	8	7
47	R:R:V50	R:R:W49	3.68	No	No	0	7	4
48	R:R:R54	R:R:W49	6	No	No	6	4	4
49	R:R:S316	R:R:W49	7.41	No	No	6	5	4
50	R:R:F309	R:R:V50	13.11	Yes	No	0	8	7
51	R:R:G52	R:R:R57	4.5	No	No	0	4	6
52	R:R:G52	R:R:L65	5.13	No	No	0	4	5
53	R:R:R54	R:R:S316	9.22	No	No	6	4	5
54	R:R:T58	R:R:T61	6.28	No	No	0	7	7
55	R:R:D122	R:R:V59	4.38	No	No	7	8	6
56	R:R:R137	R:R:V59	17	Yes	No	7	7	6
57	R:R:A142	R:R:V59	5.09	No	No	0	7	6
58	R:R:C63	R:R:I119	4.91	No	No	0	7	9
59	R:R:R123	R:R:Y64	4.12	Yes	No	0	9	8
60	R:R:V303	R:R:Y64	8.83	No	No	0	7	8
61	R:R:L115	R:R:N66	5.49	No	No	0	8	9
62	R:R:I146	R:R:N66	11.33	No	No	0	7	9
63	R:R:N66	R:R:W150	5.65	No	No	0	9	9
64	R:R:D71	R:R:L67	4.07	Yes	Yes	1	9	9
65	R:R:L115	R:R:L67	4.15	No	Yes	0	8	9
66	R:R:I116	R:R:L67	5.71	Yes	Yes	1	8	9
67	R:R:L67	R:R:N298	4.12	Yes	Yes	1	9	9
68	R:R:D71	R:R:S112	5.89	Yes	No	0	9	9
69	R:R:D71	R:R:N298	4.04	Yes	Yes	1	9	9
70	R:R:D71	R:R:P299	3.22	Yes	No	1	9	9
71	R:R:N108	R:R:S73	7.45	No	No	0	8	7
72	R:R:F74	R:R:T75	3.89	Yes	No	0	7	7
73	R:R:F74	R:R:L78	4.87	Yes	Yes	3	7	8
74	R:R:F74	R:R:V105	5.24	Yes	No	0	7	6
75	R:R:F74	R:R:N108	3.62	Yes	No	0	7	8
76	R:R:F74	R:R:L109	8.53	Yes	No	0	7	8
77	R:R:F292	R:R:F74	16.08	Yes	Yes	3	7	7
78	R:R:F74	R:R:S295	3.96	Yes	No	0	7	9
79	R:R:I101	R:R:T77	6.08	Yes	No	0	5	7
80	R:R:T77	R:R:V104	4.76	No	No	0	7	5
81	R:R:F292	R:R:L78	3.65	Yes	Yes	3	7	8
82	R:R:F80	R:R:F93	5.36	No	Yes	0	6	7
83	R:R:F80	R:R:I101	8.79	No	Yes	0	6	5
84	R:R:E89	R:R:S84	4.31	No	No	0	4	5
85	R:R:S84	R:R:W91	4.94	No	Yes	0	5	9
86	R:R:M85	R:R:N285	5.61	No	No	0	6	4
87	R:R:K90	R:R:M87	8.64	No	No	0	4	4
88	R:R:M87	R:R:P92	5.03	No	No	0	4	3
89	R:R:E89	R:R:Y175	3.37	No	Yes	0	4	3
90	R:R:D173	R:R:K90	15.21	No	No	4	3	4
91	R:R:K90	R:R:Y175	8.36	No	Yes	4	4	3
92	R:R:F93	R:R:W91	8.02	Yes	Yes	0	7	9
93	R:R:C98	R:R:W91	13.06	No	Yes	8	9	9
94	R:R:I101	R:R:W91	5.87	Yes	Yes	0	5	9
95	R:R:C176	R:R:W91	5.22	No	Yes	8	9	9
96	R:R:F93	R:R:L97	9.74	Yes	No	0	7	7
97	R:R:K99	R:R:W95	8.12	No	Yes	0	7	4
98	R:R:T165	R:R:W95	3.64	No	Yes	0	4	4
99	R:R:T166	R:R:W95	8.49	No	Yes	0	5	4
100	R:R:I101	R:R:L97	4.28	Yes	No	0	5	7
101	R:R:C98	R:R:H102	7.37	No	No	0	9	6
102	R:R:C176	R:R:C98	7.28	No	No	8	9	9
103	R:R:K99	R:R:L164	7.05	No	No	0	7	5
104	R:R:H102	R:R:L164	5.14	No	No	0	6	5
105	R:R:F161	R:R:I103	13.82	No	No	0	4	5
106	R:R:N108	R:R:V104	4.43	No	No	0	8	5
107	R:R:D106	R:R:F110	8.36	Yes	Yes	2	5	7
108	R:R:D106	R:R:T157	10.12	Yes	No	0	5	7
109	R:R:D106	R:R:V160	5.84	Yes	No	2	5	4
110	R:R:D106	R:R:R201	3.57	Yes	Yes	2	5	5
111	R:R:I107	R:R:L154	5.71	No	No	0	5	4
112	R:R:I107	R:R:T157	9.12	No	No	0	5	7
113	R:R:F110	R:R:F114	3.22	Yes	Yes	0	7	6
114	R:R:F110	R:R:L156	10.96	Yes	No	0	7	5
115	R:R:P213	R:R:V113	3.53	No	No	0	9	7
116	R:R:V113	R:R:W254	4.9	No	Yes	0	7	9
117	R:R:F114	R:R:L152	7.31	Yes	No	0	6	4
118	R:R:F250	R:R:I116	3.77	No	Yes	0	9	8
119	R:R:I116	R:R:N298	8.5	Yes	Yes	1	8	9
120	R:R:I116	R:R:Y302	10.88	Yes	Yes	1	8	9
121	R:R:F118	R:R:V145	7.87	No	No	0	7	5
122	R:R:F118	R:R:I146	5.02	No	No	0	7	7
123	R:R:I119	R:R:R123	7.52	No	Yes	1	9	9
124	R:R:I119	R:R:Y302	6.04	No	Yes	1	9	9
125	R:R:A120	R:R:V217	3.39	No	No	0	9	8
126	R:R:A120	R:R:C220	3.61	No	No	0	9	7
127	R:R:D122	R:R:R137	11.91	No	Yes	7	8	7
128	R:R:R123	R:R:Y221	10.29	Yes	Yes	1	9	8
129	R:R:R123	R:R:Y302	6.17	Yes	Yes	1	9	9
130	R:R:C124	R:R:C220	7.28	No	No	0	8	7
131	R:R:C124	R:R:L223	4.76	No	No	0	8	3
132	R:R:I125	R:R:W132	3.52	No	Yes	0	5	5
133	R:R:A133	R:R:C126	3.61	No	No	0	5	8
134	R:R:C126	R:R:R137	6.96	No	Yes	0	8	7
135	R:R:I224	R:R:V127	12.29	No	No	0	8	8
136	R:R:K227	R:R:V127	4.55	No	No	0	5	8
137	R:R:L128	R:R:L223	6.92	No	No	0	7	3
138	R:R:H129	R:R:V131	4.15	No	No	0	6	5
139	R:R:H129	R:R:W132	5.29	No	Yes	0	6	5
140	R:R:N135	R:R:V131	4.43	No	No	0	4	5
141	R:R:H136	R:R:W132	14.81	No	Yes	0	3	5
142	R:R:H136	R:R:N135	3.83	No	No	0	3	4
143	R:R:G148	R:R:P149	4.06	No	No	0	3	7
144	R:R:G148	R:R:I151	3.53	No	No	0	3	3
145	R:R:I208	R:R:L156	5.71	No	No	0	5	5
146	R:R:F161	R:R:T157	5.19	No	No	0	4	7
147	R:R:L158	R:R:P159	3.28	No	No	0	4	8
148	R:R:R201	R:R:V160	3.92	Yes	No	2	5	4
149	R:R:F163	R:R:L162	4.87	No	No	0	5	5
150	R:R:F163	R:R:W183	13.03	No	No	0	5	4
151	R:R:F163	R:R:M197	9.95	No	No	0	5	1
152	R:R:N179	R:R:T165	4.39	No	No	0	3	4
153	R:R:C176	R:R:T166	5.07	No	No	0	9	5
154	R:R:N179	R:R:V167	4.43	No	No	0	3	1
155	R:R:I169	R:R:P170	3.39	Yes	No	0	1	3
156	R:R:D173	R:R:I169	5.6	No	Yes	4	3	1
157	R:R:I169	R:R:Y175	3.63	Yes	Yes	4	1	3
158	R:R:D173	R:R:Y175	6.9	No	Yes	4	3	3
159	R:R:F178	R:R:M197	4.98	No	No	0	4	1
160	R:R:F178	R:R:R201	8.55	No	Yes	0	4	5
161	R:R:A181	R:R:N179	4.69	No	No	0	5	3
162	R:R:F180	R:R:R190	4.28	Yes	No	0	6	5
163	R:R:A194	R:R:F180	8.32	No	Yes	0	3	6
164	R:R:F180	R:R:M197	3.73	Yes	No	0	6	1
165	R:R:P187	R:R:T186	3.5	No	No	0	5	6
166	R:R:E189	R:R:T186	15.52	No	No	0	3	6
167	R:R:E188	R:R:P187	7.86	No	No	0	3	5
168	R:R:F273	R:R:L191	7.31	No	No	0	5	1
169	R:R:I195	R:R:L268	4.28	No	Yes	0	1	3
170	R:R:I195	R:R:K269	4.36	No	No	0	1	4
171	R:R:L198	R:R:L268	5.54	No	Yes	0	4	3
172	R:R:R201	R:R:R205	4.26	Yes	Yes	2	5	5
173	R:R:G202	R:R:R205	4.5	No	Yes	0	4	5
174	R:R:G202	R:R:T265	5.46	No	No	0	4	4
175	R:R:I204	R:R:I208	4.42	No	No	0	4	5
176	R:R:Q258	R:R:R205	8.18	Yes	Yes	2	8	5
177	R:R:A261	R:R:R205	5.53	No	Yes	0	5	5
178	R:R:F206	R:R:F210	4.29	Yes	Yes	2	6	9
179	R:R:F206	R:R:L211	7.31	Yes	No	0	6	4
180	R:R:F206	R:R:Q258	3.51	Yes	Yes	2	6	8
181	R:R:F206	R:R:L262	14.61	Yes	No	0	6	5
182	R:R:F210	R:R:M214	4.98	Yes	Yes	0	9	6
183	R:R:F210	R:R:F255	8.57	Yes	Yes	0	9	6
184	R:R:F210	R:R:Q258	16.4	Yes	Yes	2	9	8
185	R:R:L212	R:R:P213	4.93	No	No	0	5	9
186	R:R:F250	R:R:M214	3.73	No	Yes	0	9	6
187	R:R:F251	R:R:M214	7.46	No	Yes	0	6	6
188	R:R:L243	R:R:Y221	7.03	No	Yes	0	8	8
189	R:R:V246	R:R:Y221	6.31	Yes	Yes	1	8	8
190	R:R:Y221	R:R:Y302	5.96	Yes	Yes	1	8	9
191	R:R:K227	R:R:K231	7.18	No	No	0	5	5
192	R:R:I228	R:R:M233	4.37	No	No	0	8	3
193	R:R:I228	R:R:I234	7.36	No	No	0	8	4
194	R:R:H229	R:R:I234	3.98	No	No	0	3	4
195	R:R:K230	R:R:K231	5.75	No	No	0	4	5
196	R:R:I234	R:R:L240	5.71	No	No	0	4	5
197	R:R:R241	R:R:S237	3.95	No	No	0	5	4
198	R:R:L301	R:R:V246	8.94	No	Yes	1	8	8
199	R:R:V246	R:R:Y302	5.05	Yes	Yes	1	8	9
200	R:R:F250	R:R:W254	10.02	No	Yes	0	9	9
201	R:R:F251	R:R:F255	16.08	No	Yes	0	6	6
202	R:R:C253	R:R:L290	4.76	No	No	0	8	8
203	R:R:C253	R:R:N294	9.45	No	No	0	8	9
204	R:R:Q258	R:R:W254	3.29	Yes	Yes	0	8	9
205	R:R:A291	R:R:W254	7.78	No	Yes	0	8	9
206	R:R:N294	R:R:W254	6.78	No	Yes	0	9	9
207	R:R:F255	R:R:P256	4.33	Yes	No	0	6	9
208	R:R:F255	R:R:L259	4.87	Yes	No	0	6	5
209	R:R:F257	R:R:T287	9.08	No	No	0	7	7
210	R:R:A291	R:R:F257	5.55	No	No	0	8	7
211	R:R:T287	R:R:V260	7.93	No	No	0	7	5
212	R:R:L263	R:R:W267	6.83	No	No	0	5	3
213	R:R:G264	R:R:M271	3.49	No	No	0	4	1
214	R:R:G264	R:R:I280	3.53	No	No	0	4	4
215	R:R:V266	R:R:W267	8.58	No	No	0	4	3
216	R:R:W267	R:R:Y277	25.08	No	No	0	3	3
217	R:R:L268	R:R:M271	4.24	Yes	No	0	3	1
218	R:R:L268	R:R:L272	5.54	Yes	No	0	3	3
219	R:R:E270	R:R:Y277	3.37	No	No	0	2	3
220	R:R:F273	R:R:Y274	7.22	No	No	0	5	5
221	R:R:K276	R:R:Y274	7.17	No	No	0	1	5
222	R:R:K276	R:R:Y277	3.58	No	No	0	1	3
223	R:R:I279	R:R:L283	5.71	No	No	0	3	6
224	R:R:F292	R:R:S288	3.96	Yes	No	0	7	6
225	R:R:C296	R:R:F293	4.19	No	No	3	8	5
226	R:R:F293	R:R:L297	4.87	No	No	0	5	6
227	R:R:N294	R:R:N298	6.81	No	Yes	0	9	9
228	R:R:F304	R:R:M300	13.68	No	No	0	7	7
229	R:R:L301	R:R:Y302	5.86	No	Yes	1	8	9
230	R:R:F309	R:R:V303	7.87	Yes	No	5	8	7
231	R:R:F304	R:R:L313	3.65	No	No	0	7	6
232	R:R:Q307	R:R:R310	7.01	No	No	0	5	8
233	R:R:E311	R:R:H315	12.31	No	No	0	4	4
234	R:R:C220	R:R:L121	3.17	No	No	0	7	7
235	R:R:T58	R:R:T60	3.14	No	No	0	7	7
236	R:R:T168	R:R:T174	3.14	No	No	0	2	5
237	R:R:K144	R:R:S140	3.06	No	No	0	1	4
238	R:R:M143	R:R:V139	3.04	No	No	0	4	3
239	R:R:I203	R:R:T199	3.04	No	No	0	4	3
240	R:R:F72	R:R:G45	3.01	No	No	0	7	4
241	R:R:M55	R:R:T61	3.01	No	No	0	5	7
242	R:R:F114	R:R:G111	3.01	Yes	No	0	6	7
243	R:R:L297	R:R:S249	3	No	No	0	6	7
244	R:R:L28	R:R:V32	2.98	No	No	0	5	5
245	R:R:L39	R:R:V35	2.98	No	No	0	5	5
246	R:R:L81	R:R:V105	2.98	No	No	0	6	6
247	R:R:L100	R:R:V104	2.98	No	No	0	5	5
248	R:R:L78	R:R:T36	2.95	Yes	No	3	8	7
249	R:R:I146	R:R:I62	2.94	No	No	0	7	7
250	R:R:I279	R:R:I282	2.94	No	No	0	3	2
251	R:R:I62	R:R:M143	2.92	No	No	0	7	4
252	R:R:K231	R:R:M233	2.88	No	No	0	5	3
253	R:R:P239	R:R:R238	2.88	No	No	0	7	7
254	R:R:I48	R:R:L69	2.85	Yes	No	0	7	6
255	R:R:I125	R:R:L121	2.85	No	No	0	5	7
256	R:R:I216	R:R:L212	2.85	No	No	0	6	5
257	R:R:I219	R:R:L223	2.85	No	No	0	3	3
258	R:R:I224	R:R:L243	2.85	No	No	0	8	8
259	R:R:I169	R:R:N171	2.83	Yes	No	0	1	4
260	R:R:K227	R:R:L128	2.82	No	No	0	5	7
261	R:R:L42	R:R:L46	2.77	No	No	0	4	6
262	R:R:A51	R:R:F309	2.77	No	Yes	0	7	8
263	R:R:A153	R:R:F114	2.77	No	Yes	0	8	6
264	R:R:L158	R:R:L162	2.77	No	No	0	4	5
265	R:R:L259	R:R:L263	2.77	No	No	0	5	5
266	R:R:N135	R:R:Q134	2.64	No	No	0	4	5
267	R:R:F37	R:R:V38	2.62	Yes	No	0	6	5
268	R:R:R312	R:R:V50	2.62	No	No	0	5	7
269	R:R:R137	R:R:T60	2.59	Yes	No	0	7	7
270	R:R:A70	R:R:W150	2.59	No	No	0	8	9
271	R:R:V247	R:R:Y221	2.52	No	Yes	0	8	8
272	R:R:F53	R:R:I48	2.51	No	Yes	0	4	7
273	R:R:M55	R:R:R312	2.48	No	No	0	5	5
274	R:R:S182	R:R:W183	2.47	No	No	0	7	4
275	R:R:G184	R:R:G185	2.11	No	No	0	3	3
276	R:R:G209	R:R:P213	2.03	No	No	0	6	9
277	R:R:F96	R:R:W95	2	No	Yes	0	1	4
278	R:R:C296	R:R:G40	1.96	No	No	0	8	8
279	R:R:A20	R:R:G21	1.95	No	No	0	4	4
280	R:R:P286	R:R:P29	1.95	No	No	0	6	5
281	R:R:A120	R:R:G117	1.95	No	No	0	9	7
282	R:R:G21	R:R:S19	1.86	No	No	0	4	4
283	R:R:G148	R:R:V147	1.84	No	No	0	3	4
284	R:R:G306	R:R:V305	1.84	No	No	0	8	7
285	R:R:G185	R:R:T186	1.82	No	No	0	3	6
286	R:R:G34	R:R:I82	1.76	No	No	0	5	7
287	R:R:G275	R:R:K278	1.74	No	No	0	1	1
288	R:R:G40	R:R:L39	1.71	No	No	0	8	5
289	R:R:G43	R:R:L42	1.71	No	No	0	8	4
290	R:R:E89	R:R:G88	1.64	No	No	0	4	3
291	R:R:L240	R:R:P239	1.64	No	No	0	5	7
292	R:R:C253	R:R:I252	1.64	No	No	0	8	6
293	R:R:A218	R:R:M214	1.61	No	Yes	0	5	6
294	R:R:V31	R:R:V32	1.6	No	No	0	6	5
295	R:R:V242	R:R:V246	1.6	No	Yes	0	8	8
296	R:R:V242	R:R:V305	1.6	No	No	0	8	7
297	R:R:A86	R:R:L30	1.58	No	No	0	4	5
298	R:R:A225	R:R:L243	1.58	No	No	0	5	8
299	R:R:A245	R:R:L301	1.58	No	No	0	6	8
300	R:R:T56	R:R:T58	1.57	No	No	0	6	7
301	R:R:T166	R:R:T174	1.57	No	No	0	5	5
302	R:R:I203	R:R:V207	1.54	No	No	0	4	4
303	R:R:I208	R:R:V207	1.54	No	No	0	5	4
304	R:R:H129	R:R:P130	1.53	No	No	0	6	8
305	R:R:I27	R:R:T23	1.52	No	No	0	6	2
306	R:R:F93	R:R:G94	1.51	Yes	No	0	7	8
307	R:R:G184	R:R:R190	1.5	No	No	0	3	5
308	R:R:L141	R:R:T138	1.47	No	No	0	3	6
309	R:R:I279	R:R:I280	1.47	No	No	0	3	4
310	R:R:I195	R:R:K192	1.45	No	No	0	1	5
311	R:R:G275	R:R:Y274	1.45	No	No	0	1	5
312	R:R:F114	R:R:P149	1.44	Yes	No	0	6	7
313	R:R:I282	R:R:L25	1.43	No	No	0	2	3
314	R:R:I82	R:R:L30	1.43	No	No	0	7	5
315	R:R:H315	R:R:I314	1.33	No	No	0	4	3
316	R:R:R238	R:R:S236	1.32	No	No	0	7	6
317	R:R:F180	R:R:V193	1.31	Yes	No	0	6	4
318	R:R:L141	R:R:W132	1.14	No	Yes	0	3	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:?1	11.2225	8	2	0
2	L:L:F3	5.785	4	0	0
3	R:R:L33	5.0475	4	3	7
4	R:R:F37	5.405	4	0	6
5	R:R:V47	6.93	4	5	9
6	R:R:I48	3.2225	4	0	7
7	R:R:L67	4.5125	4	1	9
8	R:R:D71	4.79	5	1	9
9	R:R:F74	6.59857	7	3	7
10	R:R:L78	3.854	5	3	8
11	R:R:W91	7.422	5	8	9
12	R:R:F93	6.1575	4	0	7
13	R:R:W95	5.5625	4	0	4
14	R:R:I101	6.255	4	0	5
15	R:R:D106	8.532	5	2	5
16	R:R:F110	9.7775	4	2	7
17	R:R:F114	3.55	5	0	6
18	R:R:I116	7.215	4	1	8
19	R:R:R123	7.025	4	1	9
20	R:R:W132	6.19	4	0	5
21	R:R:R137	9.615	4	7	7
22	R:R:I169	3.8625	4	4	1
23	R:R:Y175	5.565	4	4	3
24	R:R:F180	4.41	4	0	6
25	R:R:R201	6.264	5	2	5
26	R:R:R205	7.95167	6	2	5
27	R:R:F206	7.43	4	2	6
28	R:R:F210	8.56	4	2	9
29	R:R:M214	4.445	4	0	6
30	R:R:Y221	6.422	5	1	8
31	R:R:V246	5.475	4	1	8
32	R:R:W254	6.495	6	0	9
33	R:R:F255	8.4625	4	0	6
34	R:R:Q258	7.845	4	2	8
35	R:R:L268	5.062	5	0	3
36	R:R:F292	7.445	4	3	7
37	R:R:N298	5.8675	4	1	9
38	R:R:Y302	6.66	6	1	9
39	R:R:F309	8.2325	4	5	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	L:L:L2	36.114	3.77	Yes	No	0	0	0
2	L:L:I4	L:L:L2	41.101	4.28	No	No	0	0	0
3	L:L:?1	R:R:R205	39.9413	22.03	Yes	Yes	2	0	5
4	L:L:F3	R:R:R205	47.6463	3.21	Yes	Yes	0	0	5
5	L:L:F3	L:L:I5	15.7125	7.54	Yes	No	0	0	0
6	L:L:F3	R:R:G264	28.244	4.52	Yes	No	0	0	4
7	L:L:I4	R:R:H102	46.7846	5.3	No	No	0	0	6
8	L:L:?1	R:R:R201	17.4497	11.02	Yes	Yes	2	0	5
9	R:R:F178	R:R:R201	30.1279	8.55	No	Yes	0	4	5
10	L:L:I5	R:R:L268	11.8577	5.71	No	Yes	0	0	3
11	R:R:G264	R:R:I280	24.7376	3.53	No	No	0	4	4
12	R:R:I279	R:R:I280	22.6933	1.47	No	No	0	3	4
13	R:R:I279	R:R:I282	18.5773	2.94	No	No	0	3	2
14	R:R:I282	R:R:Y22	14.617	4.84	No	No	0	2	2
15	L:L:?1	R:R:L109	51.0061	8.79	Yes	No	0	0	8
16	R:R:F74	R:R:L109	50.1398	8.53	Yes	No	0	7	8
17	R:R:F74	R:R:L78	30.7788	4.87	Yes	Yes	3	7	8
18	R:R:L33	R:R:L78	18.3664	4.15	Yes	Yes	3	7	8
19	R:R:L33	R:R:M85	21.5978	4.24	Yes	No	0	7	6
20	R:R:M85	R:R:N285	19.2098	5.61	No	No	0	6	4
21	R:R:N285	R:R:P29	16.4963	13.03	No	No	0	4	5
22	R:R:L28	R:R:P29	11.0327	3.28	No	No	0	5	5
23	R:R:F292	R:R:F74	19.4527	16.08	Yes	Yes	3	7	7
24	R:R:F292	R:R:L33	16.6384	6.09	Yes	Yes	3	7	7
25	R:R:I82	R:R:L33	11.0327	5.71	No	Yes	0	7	7
26	R:R:L78	R:R:T36	11.656	2.95	Yes	No	3	8	7
27	L:L:?1	R:R:W254	94.3439	6.2	Yes	Yes	0	0	9
28	R:R:N294	R:R:W254	16.6201	6.78	No	Yes	0	9	9
29	R:R:N294	R:R:N298	14.4016	6.81	No	Yes	0	9	9
30	R:R:D71	R:R:N44	10.6981	6.73	Yes	No	1	9	9
31	R:R:F250	R:R:W254	84.975	10.02	No	Yes	0	9	9
32	R:R:F250	R:R:I116	99.0329	3.77	No	Yes	0	9	8
33	R:R:I116	R:R:Y302	100	10.88	Yes	Yes	1	8	9
34	R:R:R123	R:R:Y302	45.0841	6.17	Yes	Yes	1	9	9
35	R:R:R123	R:R:Y64	50.5661	4.12	Yes	No	0	9	8
36	R:R:V303	R:R:Y64	49.4202	8.83	No	No	0	7	8
37	R:R:V303	R:R:V47	21.1074	11.22	No	Yes	5	7	9
38	R:R:A68	R:R:V47	11.3444	3.39	No	Yes	0	8	9
39	R:R:F309	R:R:V303	26.9515	7.87	Yes	No	5	8	7
40	R:R:F309	R:R:V50	25.1043	13.11	Yes	No	0	8	7
41	R:R:R312	R:R:V50	18.9989	2.62	No	No	0	5	7
42	R:R:M55	R:R:R312	17.4451	2.48	No	No	0	5	5
43	R:R:M55	R:R:T61	15.8867	3.01	No	No	0	5	7
44	R:R:T58	R:R:T61	14.3191	6.28	No	No	0	7	7
45	R:R:T58	R:R:T60	11.1564	3.14	No	No	0	7	7
46	R:R:I116	R:R:L67	19.274	5.71	Yes	Yes	1	8	9
47	R:R:L115	R:R:L67	23.005	4.15	No	Yes	0	8	9
48	R:R:L115	R:R:N66	20.7453	5.49	No	No	0	8	9
49	R:R:I146	R:R:N66	13.9112	11.33	No	No	0	7	9
50	R:R:F74	R:R:N108	15.7721	3.62	Yes	No	0	7	8
51	R:R:C98	R:R:H102	33.3501	7.37	No	No	0	9	6
52	R:R:C98	R:R:W91	25.6314	13.06	No	Yes	8	9	9
53	R:R:N108	R:R:V104	13.1686	4.43	No	No	0	8	5
54	R:R:T77	R:R:V104	10.5927	4.76	No	No	0	7	5
55	R:R:S84	R:R:W91	18.4397	4.94	No	Yes	0	5	9
56	R:R:E89	R:R:S84	16.7942	4.31	No	No	0	4	5
57	R:R:E89	R:R:Y175	13.4757	3.37	No	Yes	0	4	3
58	R:R:H102	R:R:L164	12.6186	5.14	No	No	0	6	5
59	R:R:K99	R:R:L164	11.0969	7.05	No	No	0	7	5
60	L:L:?1	R:R:F110	20.9653	16.57	Yes	Yes	2	0	7
61	R:R:F110	R:R:F114	12.3894	3.22	Yes	Yes	0	7	6
62	R:R:Y221	R:R:Y302	45.8817	5.96	Yes	Yes	1	8	9
63	R:R:L243	R:R:Y221	50.4056	7.03	No	Yes	0	8	8
64	R:R:I224	R:R:L243	47.8847	2.85	No	No	0	8	8
65	R:R:I224	R:R:V127	46.5234	12.29	No	No	0	8	8
66	R:R:K227	R:R:V127	45.3225	4.55	No	No	0	5	8
67	R:R:K227	R:R:L128	29.5916	2.82	No	No	0	5	7
68	R:R:L128	R:R:L223	28.1111	6.92	No	No	0	7	3
69	R:R:C124	R:R:L223	25.118	4.76	No	No	0	8	3
70	R:R:C124	R:R:C220	23.6054	7.28	No	No	0	8	7
71	R:R:C220	R:R:L121	17.4634	3.17	No	No	0	7	7
72	R:R:I125	R:R:L121	15.905	2.85	No	No	0	5	7
73	R:R:I125	R:R:W132	14.3374	3.52	No	Yes	0	5	5
74	R:R:F178	R:R:M197	27.3777	4.98	No	No	0	4	1
75	R:R:F180	R:R:M197	16.3909	3.73	Yes	No	0	6	1
76	R:R:F180	R:R:R190	11.624	4.28	Yes	No	0	6	5
77	R:R:G184	R:R:R190	10.116	1.5	No	No	0	3	5
78	R:R:Q258	R:R:R205	33.4601	8.18	Yes	Yes	2	8	5
79	R:R:F210	R:R:Q258	24.1509	16.4	Yes	Yes	2	9	8
80	R:R:F210	R:R:F255	29.0737	8.57	Yes	Yes	0	9	6
81	R:R:F255	R:R:L259	30.7421	4.87	Yes	No	0	6	5
82	R:R:L259	R:R:L263	28.2119	2.77	No	No	0	5	5
83	R:R:L263	R:R:W267	25.6726	6.83	No	No	0	5	3
84	R:R:W267	R:R:Y277	20.5665	25.08	No	No	0	3	3
85	R:R:K276	R:R:Y277	15.4238	3.58	No	No	0	1	3
86	R:R:K276	R:R:Y274	12.8386	7.17	No	No	0	1	5
87	R:R:Q258	R:R:W254	28.7161	3.29	Yes	Yes	0	8	9
88	R:R:F250	R:R:M214	18.811	3.73	No	Yes	0	9	6
89	R:R:K227	R:R:K231	16.0838	7.18	No	No	0	5	5
90	R:R:K231	R:R:M233	12.9395	2.88	No	No	0	5	3
91	R:R:I228	R:R:M233	11.3535	4.37	No	No	0	8	3
92	L:L:I4	R:R:F178	15.5658	5.02	No	No	0	0	4
93	R:R:R201	R:R:R205	13.0036	4.26	Yes	Yes	2	5	5

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?1	R:R:D106	14.77	2	Yes	Yes	0	5	0	1
L:L:?1	R:R:L109	8.79	2	Yes	No	0	8	0	1
L:L:?1	R:R:F110	16.57	2	Yes	Yes	0	7	0	1
L:L:?1	R:R:R201	11.02	2	Yes	Yes	0	5	0	1
L:L:?1	R:R:R205	22.03	2	Yes	Yes	0	5	0	1
L:L:?1	R:R:W254	6.2	2	Yes	Yes	0	9	0	1
L:L:?1	R:R:F257	6.63	2	Yes	No	0	7	0	1
L:L:L2	R:R:V105	5.96	0	No	No	0	6	0	1
L:L:F3	R:R:R205	3.21	0	Yes	Yes	0	5	0	1
L:L:F3	R:R:G264	4.52	0	Yes	No	0	4	0	1
L:L:F3	R:R:V284	7.87	0	Yes	No	0	5	0	1
L:L:I4	R:R:H102	5.3	0	No	No	0	6	0	1
L:L:I4	R:R:F178	5.02	0	No	No	0	4	0	1
L:L:I5	R:R:T177	7.6	0	No	No	0	3	0	1
L:L:I5	R:R:L268	5.71	0	No	Yes	0	3	0	1
R:R:F74	R:R:V105	5.24	3	Yes	No	7	6	2	1
R:R:F74	R:R:L109	8.53	3	Yes	No	7	8	2	1
R:R:C98	R:R:H102	7.37	8	No	No	9	6	2	1
R:R:H102	R:R:L164	5.14	0	No	No	6	5	1	2
R:R:D106	R:R:F110	8.36	2	Yes	Yes	5	7	1	1
R:R:D106	R:R:T157	10.12	2	Yes	No	5	7	1	2
R:R:D106	R:R:V160	5.84	2	Yes	No	5	4	1	2
R:R:D106	R:R:R201	3.57	2	Yes	Yes	5	5	1	1
R:R:F110	R:R:F114	3.22	2	Yes	Yes	7	6	1	2
R:R:F110	R:R:L156	10.96	2	Yes	No	7	5	1	2
R:R:V113	R:R:W254	4.9	0	No	Yes	7	9	2	1
R:R:R201	R:R:V160	3.92	2	Yes	No	5	4	1	2
R:R:F178	R:R:M197	4.98	0	No	No	4	1	1	2
R:R:F178	R:R:R201	8.55	0	No	Yes	4	5	1	1
R:R:I195	R:R:L268	4.28	0	No	Yes	1	3	2	1
R:R:L198	R:R:L268	5.54	0	No	Yes	4	3	2	1
R:R:R201	R:R:R205	4.26	2	Yes	Yes	5	5	1	1
R:R:G202	R:R:R205	4.5	0	No	Yes	4	5	2	1
R:R:Q258	R:R:R205	8.18	2	Yes	Yes	8	5	2	1
R:R:A261	R:R:R205	5.53	0	No	Yes	5	5	2	1
R:R:F250	R:R:W254	10.02	0	No	Yes	9	9	2	1
R:R:Q258	R:R:W254	3.29	2	Yes	Yes	8	9	2	1
R:R:A291	R:R:W254	7.78	0	No	Yes	8	9	2	1
R:R:N294	R:R:W254	6.78	0	No	Yes	9	9	2	1
R:R:F257	R:R:T287	9.08	0	No	No	7	7	1	2
R:R:A291	R:R:F257	5.55	0	No	No	8	7	2	1
R:R:G264	R:R:M271	3.49	0	No	No	4	1	1	2
R:R:G264	R:R:I280	3.53	0	No	No	4	4	1	2
R:R:L268	R:R:M271	4.24	0	Yes	No	3	1	1	2
R:R:L268	R:R:L272	5.54	0	Yes	No	3	3	1	2
R:R:L81	R:R:V105	2.98	0	No	No	6	6	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	7WVV_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.21
Number of Linked Nodes	287
Number of Links	318
Number of Hubs	39
Number of Links mediated by Hubs	139
Number of Communities	8
Number of Nodes involved in Communities	44
Number of Links involved in Communities	57

Path Summary
Number Of Nodes in MetaPath	94
Number Of Links MetaPath	93
Number of Shortest Paths	56681
Length Of Smallest Path	3
Average Path Length	13.5166
Length of Longest Path	31
Minimum Path Strength	1.305
Average Path Strength	6.49008
Maximum Path Strength	19.3
Minimum Path Correlation	0.7
Average Path Correlation	0.9325
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	3.84615
Average % Of Corr. Nodes	53.1169
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	40.2098
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain • G protein-coupled receptor-like
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain • G protein-coupled receptor-like
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	FME
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	FME
Name	N-Formylmethionine
Synonyms	Formyl-methionine N-Formylmethionine N-formyl-L-methionine (2S)-2-(formylamino)-4-(methylthio)butanoic acid L-N-Formylmethionine
Identifier
Formula	C6 H11 N O3 S
Molecular Weight	177.221
SMILES
PubChem	439750
Formal Charge	0
Total Atoms	22
Total Chiral Atoms	1
Total Bonds	21
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P25090
Sequence	>7WVV_nogp_Chain_R S A G Y T V L R I L P L V V L G V T F V L G V L G N G L V I W V A G F R M T R T V T T I C Y L N L A L A D F S F T A T L P F L I V S M A M G E K W P F G W F L C K L I H I V V D I N L F G S V F L I G F I A L D R C I C V L H P V W A Q N H R T V S L A M K V I V G P W I L A L V L T L P V F L F L T T V T I P N G D T Y C T F N F A S W G G T P E E R L K V A I T M L T A R G I I R F V I G F L L P M S I V A I C Y G L I A A K I H K K G M I K S S R P L R V L T A V V A S F F I C W F P F Q L V A L L G T V W L K E M L F Y G K Y K I I D I L V N P T S S L A F F N S C L N P M L Y V F V G Q D F R E R L I H S Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	6OMM	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	WKYMVX	-	Gi1/β1/γ2	3.17	2020-02-26	doi.org/10.1038/s41467-020-14728-9
	6OMM (No Gprot)	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	WKYMVX	-		3.17	2020-02-26	doi.org/10.1038/s41467-020-14728-9
	6LW5	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	WKYMVm	-	-	2.8	2020-03-25	doi.org/10.1038/s41467-020-15009-1
	7T6S	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	PubChem 24776341	-	Gi1/β1/γ2	3	2022-03-30	doi.org/10.1038/s41467-022-28586-0
	7T6S (No Gprot)	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	PubChem 24776341	-		3	2022-03-30	doi.org/10.1038/s41467-022-28586-0
	7T6U	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	CGEN-855A	-	Gi1/β1/γ2	2.9	2022-03-30	doi.org/10.1038/s41467-022-28586-0
	7T6U (No Gprot)	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	CGEN-855A	-		2.9	2022-03-30	doi.org/10.1038/s41467-022-28586-0
	7T6V	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	fMLFII	-	Gi1/β1/γ2	3.1	2022-03-30	doi.org/10.1038/s41467-022-28586-0
	7T6V (No Gprot)	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	fMLFII	-		3.1	2022-03-30	doi.org/10.1038/s41467-022-28586-0
	7WVV	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	fMLFII	-	Gi2/β1/γ2	2.9	2022-04-13	doi.org/10.1038/s41467-022-29361-x
	7WVV (No Gprot)	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	fMLFII	-		2.9	2022-04-13	doi.org/10.1038/s41467-022-29361-x
	7WVW	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	fMYFINILTL	-	Gi2/β1/γ2	3.1	2022-04-13	doi.org/10.1038/s41467-022-29361-x
	7WVW (No Gprot)	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	fMYFINILTL	-		3.1	2022-04-13	doi.org/10.1038/s41467-022-29361-x
	7WVX	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	Humanin	-	Gi2/β1/γ2	2.8	2022-04-13	doi.org/10.1038/s41467-022-29361-x
	7WVX (No Gprot)	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	Humanin	-		2.8	2022-04-13	doi.org/10.1038/s41467-022-29361-x
	7WVY	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	Amyloid-β42	-	Gi2/β1/γ2	3	2022-04-13	doi.org/10.1038/s41467-022-29361-x
	7WVY (No Gprot)	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	Amyloid-β42	-		3	2022-04-13	doi.org/10.1038/s41467-022-29361-x
	8Y62	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	C16:0 Ceramide	-	Gi1/β1/γ2	3.2	2025-02-05	doi.org/10.1126/science.ado4188
	8Y62 (No Gprot)	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	C16:0 Ceramide	-		3.2	2025-02-05	doi.org/10.1126/science.ado4188
	8Y63	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	C20:0 Ceramide	-	Gi1/β1/γ2	3.2	2025-02-05	doi.org/10.1126/science.ado4188
	8Y63 (No Gprot)	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	C20:0 Ceramide	-		3.2	2025-02-05	doi.org/10.1126/science.ado4188
	9JHJ	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	C18:0 Ceramide	-	Gi1/β1/γ2	3.2	2025-03-19	doi.org/10.1126/science.ado4188
	9JHJ (No Gprot)	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	C18:0 Ceramide	-		3.2	2025-03-19	doi.org/10.1126/science.ado4188

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