psnGPCR

Press and hold down the left mouse button and move the mouse to rotate.
Press and hold down the central mouse button and move the mouse to translate.
Use the mouse wheel to zoom in or out.
Click on any atom on your molecule and the corresponding residue label will be placed beneath the viewer.

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:F27	4.89	Yes	Yes	1	0	5
2	L:L:?1	R:R:F88	4.89	Yes	Yes	0	0	7
3	L:L:?1	R:R:M118	6.82	Yes	Yes	0	0	7
4	L:L:?1	R:R:T119	4.74	Yes	Yes	1	0	5
5	L:L:?1	R:R:E204	4.26	Yes	No	0	0	5
6	L:L:?1	R:R:D208	10.9	Yes	Yes	1	0	5
7	L:L:?1	R:R:F211	4.89	Yes	Yes	1	0	5
8	L:L:?1	R:R:I280	8.03	Yes	No	1	0	6
9	L:L:?1	R:R:I284	4.59	Yes	No	1	0	5
10	L:L:?1	R:R:I287	4.59	Yes	No	0	0	5
11	R:R:R183	R:R:T23	7.76	Yes	No	0	3	8
12	R:R:R24	R:R:T195	6.47	No	No	0	5	4
13	R:R:I197	R:R:R24	3.76	No	No	0	4	5
14	R:R:F25	R:R:P26	4.33	Yes	No	0	5	5
15	R:R:F25	R:R:F27	7.5	Yes	Yes	0	5	5
16	R:R:F25	R:R:I287	5.02	Yes	No	0	5	5
17	R:R:F25	R:R:Q290	4.68	Yes	No	0	5	4
18	R:R:F25	R:R:I298	11.3	Yes	No	0	5	3
19	R:R:F25	R:R:F303	5.36	Yes	Yes	0	5	4
20	R:R:P26	R:R:S29	5.34	No	No	0	5	9
21	R:R:P26	R:R:R183	4.32	No	Yes	0	5	3
22	R:R:F115	R:R:F27	8.57	Yes	Yes	1	5	5
23	R:R:F177	R:R:F27	7.5	Yes	Yes	1	5	5
24	R:R:F28	R:R:V95	11.8	Yes	No	0	8	6
25	R:R:F28	R:R:V98	3.93	Yes	No	0	8	5
26	R:R:F115	R:R:F28	5.36	Yes	Yes	1	5	8
27	R:R:F28	R:R:F303	6.43	Yes	Yes	1	8	4
28	R:R:F28	R:R:V307	7.87	Yes	No	1	8	5
29	R:R:S29	R:R:W104	9.88	No	Yes	4	9	9
30	R:R:I193	R:R:S29	4.64	No	No	4	4	9
31	R:R:D30	R:R:K32	4.15	No	Yes	0	6	3
32	R:R:D30	R:R:P300	4.83	No	No	0	6	4
33	R:R:K32	R:R:R99	7.43	Yes	No	5	3	4
34	R:R:K32	R:R:S301	4.59	Yes	No	5	3	2
35	R:R:D34	R:R:H35	3.78	No	No	0	3	3
36	R:R:D34	R:R:L39	6.79	No	No	0	3	4
37	R:R:L37	R:R:R36	4.86	No	No	0	3	4
38	R:R:E43	R:R:V42	5.7	No	No	0	5	5
39	R:R:E43	R:R:F304	9.33	No	No	0	5	4
40	R:R:E43	R:R:W305	15.27	No	No	0	5	4
41	R:R:L96	R:R:T44	5.9	No	No	0	6	6
42	R:R:V46	R:R:W305	4.9	No	No	0	6	4
43	R:R:I92	R:R:L47	4.28	Yes	Yes	0	7	6
44	R:R:L47	R:R:L96	6.92	Yes	No	0	6	6
45	R:R:F304	R:R:L47	6.09	No	Yes	0	4	6
46	R:R:F51	R:R:I89	6.28	No	Yes	6	6	6
47	R:R:F51	R:R:I92	6.28	No	Yes	6	6	7
48	R:R:I89	R:R:S54	9.29	Yes	No	0	6	8
49	R:R:F82	R:R:N58	4.83	Yes	Yes	3	9	9
50	R:R:D85	R:R:N58	17.5	No	Yes	0	9	9
51	R:R:L86	R:R:N58	9.61	No	Yes	0	7	9
52	R:R:N58	R:R:P318	9.77	Yes	No	3	9	9
53	R:R:A61	R:R:F82	8.32	No	Yes	0	8	9
54	R:R:F82	R:R:L62	4.87	Yes	No	0	9	6
55	R:R:R67	R:R:V63	3.92	No	No	0	6	4
56	R:R:L64	R:R:N322	4.12	No	Yes	3	7	7
57	R:R:L64	R:R:T324	7.37	No	No	3	7	7
58	R:R:L79	R:R:V65	5.96	No	No	0	5	7
59	R:R:R68	R:R:T324	6.47	No	No	0	6	7
60	R:R:C76	R:R:E135	6.08	No	No	0	5	8
61	R:R:L159	R:R:L77	4.15	No	No	0	7	7
62	R:R:F82	R:R:V78	3.93	Yes	No	0	9	8
63	R:R:N80	R:R:V124	4.43	Yes	Yes	7	9	7
64	R:R:N80	R:R:T128	8.77	Yes	No	0	9	8
65	R:R:L159	R:R:N80	4.12	No	Yes	0	7	9
66	R:R:N80	R:R:W163	13.56	Yes	No	7	9	9
67	R:R:L81	R:R:T128	4.42	No	No	0	9	8
68	R:R:L129	R:R:L81	5.54	No	No	2	8	9
69	R:R:L81	R:R:Y321	3.52	No	Yes	2	9	9
70	R:R:F82	R:R:P318	4.33	Yes	No	3	9	9
71	R:R:F82	R:R:N322	4.83	Yes	Yes	3	9	7
72	R:R:L87	R:R:S121	9.01	No	No	0	6	8
73	R:R:F88	R:R:S121	6.61	Yes	No	0	7	8
74	R:R:F311	R:R:F88	9.65	Yes	Yes	0	7	7
75	R:R:I89	R:R:I92	5.89	Yes	Yes	6	6	7
76	R:R:F311	R:R:I92	12.56	Yes	Yes	0	7	7
77	R:R:L114	R:R:L94	6.92	No	No	0	6	5
78	R:R:V98	R:R:W104	13.48	No	Yes	0	5	9
79	R:R:R99	R:R:S301	3.95	No	No	5	4	2
80	R:R:F304	R:R:R99	27.79	No	No	0	4	4
81	R:R:C111	R:R:W104	5.22	No	Yes	4	9	9
82	R:R:I193	R:R:W104	5.87	No	Yes	4	4	9
83	R:R:C194	R:R:W104	10.45	No	Yes	4	9	9
84	R:R:G107	R:R:P108	4.06	No	No	0	8	3
85	R:R:P108	R:R:V179	5.3	No	No	0	3	5
86	R:R:C111	R:R:C194	7.28	No	No	4	9	9
87	R:R:H112	R:R:R178	4.51	No	No	0	7	4
88	R:R:F115	R:R:L114	3.65	Yes	No	0	5	6
89	R:R:L114	R:R:M118	4.24	No	Yes	0	6	7
90	R:R:F115	R:R:F177	7.5	Yes	Yes	1	5	5
91	R:R:L120	R:R:Y116	4.69	No	No	0	5	5
92	R:R:C174	R:R:Y116	9.41	No	No	0	4	5
93	R:R:F311	R:R:M118	3.73	Yes	Yes	0	7	7
94	R:R:L173	R:R:T119	4.42	No	Yes	0	5	5
95	R:R:F211	R:R:T119	3.89	Yes	Yes	1	5	5
96	R:R:G122	R:R:T125	3.64	No	No	0	7	9
97	R:R:N215	R:R:S123	8.94	Yes	No	0	6	6
98	R:R:V124	R:R:W163	18.39	Yes	No	7	7	9
99	R:R:S166	R:R:V124	4.85	No	Yes	0	8	7
100	R:R:F273	R:R:I126	3.77	Yes	No	2	9	8
101	R:R:I126	R:R:W277	14.09	No	Yes	2	8	9
102	R:R:L127	R:R:N215	4.12	No	Yes	0	6	6
103	R:R:F273	R:R:L129	3.65	Yes	No	2	9	8
104	R:R:L129	R:R:Y321	7.03	No	Yes	2	8	9
105	R:R:R136	R:R:V132	5.23	Yes	No	0	9	8
106	R:R:I223	R:R:S133	6.19	No	No	2	8	8
107	R:R:S133	R:R:S226	6.52	No	No	0	8	5
108	R:R:S133	R:R:Y227	5.09	No	Yes	2	8	9
109	R:R:L134	R:R:V222	4.47	No	No	0	5	6
110	R:R:E135	R:R:R136	3.49	No	Yes	0	8	9
111	R:R:R136	R:R:Y227	7.2	Yes	Yes	2	9	9
112	R:R:R136	R:R:Y321	5.14	Yes	Yes	2	9	9
113	R:R:M137	R:R:S226	9.2	No	No	0	8	5
114	R:R:K229	R:R:M137	5.76	Yes	No	0	5	8
115	R:R:I140	R:R:I230	4.42	No	No	0	8	8
116	R:R:L214	R:R:Y165	7.03	No	No	0	4	4
117	R:R:N215	R:R:Y165	9.3	Yes	No	0	6	4
118	R:R:L171	R:R:P172	4.93	No	No	0	5	8
119	R:R:P172	R:R:W207	12.16	No	Yes	0	8	6
120	R:R:F177	R:R:L173	3.65	Yes	No	0	5	5
121	R:R:L173	R:R:W207	7.97	No	Yes	0	5	6
122	R:R:F176	R:R:V175	3.93	No	No	0	5	4
123	R:R:F176	R:R:P199	7.22	No	No	0	5	6
124	R:R:F177	R:R:L196	12.18	Yes	No	0	5	5
125	R:R:P181	R:R:V180	5.3	No	No	0	2	4
126	R:R:I193	R:R:R183	6.26	No	Yes	0	4	3
127	R:R:L196	R:R:W198	17.08	No	Yes	0	5	7
128	R:R:E204	R:R:W198	31.62	No	Yes	0	5	7
129	R:R:W198	R:R:W207	11.25	Yes	Yes	0	7	6
130	R:R:P202	R:R:T200	3.5	No	No	0	3	3
131	R:R:E204	R:R:N291	9.2	No	No	0	5	2
132	R:R:D208	R:R:W207	7.82	Yes	Yes	0	5	6
133	R:R:F211	R:R:W207	7.02	Yes	Yes	0	5	6
134	R:R:D208	R:R:I284	4.2	Yes	No	1	5	5
135	R:R:D208	R:R:L288	6.79	Yes	No	0	5	4
136	R:R:F211	R:R:N215	9.67	Yes	Yes	0	5	6
137	R:R:I281	R:R:V212	4.61	No	No	0	7	6
138	R:R:L285	R:R:V212	4.47	No	No	0	6	6
139	R:R:F216	R:R:F273	4.29	Yes	Yes	0	8	9
140	R:R:F216	R:R:S278	5.28	Yes	No	0	8	7
141	R:R:F216	R:R:I281	13.82	Yes	No	0	8	7
142	R:R:P219	R:R:V218	3.53	No	No	0	9	5
143	R:R:I225	R:R:L221	7.14	No	No	0	4	2
144	R:R:I223	R:R:Y227	4.84	No	Yes	2	8	9
145	R:R:I225	R:R:K229	4.36	No	Yes	0	4	5
146	R:R:L266	R:R:Y227	4.69	No	Yes	0	8	9
147	R:R:L269	R:R:Y227	5.86	No	Yes	2	8	9
148	R:R:M270	R:R:Y227	4.79	No	Yes	0	8	9
149	R:R:Y227	R:R:Y321	3.97	Yes	Yes	2	9	9
150	R:R:K229	R:R:Q232	10.85	Yes	No	0	5	4
151	R:R:L231	R:R:L266	11.07	No	No	0	6	8
152	R:R:L262	R:R:T234	4.42	No	No	0	8	8
153	R:R:K235	R:R:R238	4.95	No	No	8	5	4
154	R:R:K235	R:R:K239	8.62	No	No	8	5	5
155	R:R:R240	R:R:S237	3.95	No	No	0	3	6
156	R:R:K239	R:R:R238	13.61	No	No	8	5	4
157	R:R:D259	R:R:R238	11.91	No	No	0	7	4
158	R:R:L241	R:R:Y247	4.69	No	Yes	0	5	4
159	R:R:H251	R:R:Y247	9.8	Yes	Yes	9	2	4
160	R:R:Q252	R:R:Y247	4.51	No	Yes	0	2	4
161	R:R:V255	R:R:Y247	7.57	No	Yes	9	5	4
162	R:R:H251	R:R:R254	4.51	Yes	No	0	2	4
163	R:R:H251	R:R:V255	4.15	Yes	No	9	2	5
164	R:R:R264	R:R:T265	3.88	No	No	0	7	8
165	R:R:F267	R:R:V271	9.18	No	No	0	5	5
166	R:R:L269	R:R:L320	4.15	No	No	0	8	8
167	R:R:L269	R:R:Y321	4.69	No	Yes	2	8	9
168	R:R:M276	R:R:S272	4.6	Yes	No	0	8	6
169	R:R:F273	R:R:F274	7.5	Yes	No	0	9	6
170	R:R:F273	R:R:W277	5.01	Yes	Yes	2	9	9
171	R:R:M276	R:R:N313	11.22	Yes	No	0	8	9
172	R:R:L316	R:R:M276	5.65	No	Yes	0	6	8
173	R:R:T310	R:R:W277	3.64	No	Yes	0	8	9
174	R:R:N313	R:R:W277	18.08	No	Yes	0	9	9
175	R:R:F309	R:R:P279	10.11	No	No	0	7	9
176	R:R:I280	R:R:I284	4.42	No	No	1	6	5
177	R:R:I280	R:R:T310	4.56	No	No	0	6	8
178	R:R:L286	R:R:V297	4.47	No	No	0	5	4
179	R:R:F292	R:R:L288	4.87	No	No	0	1	4
180	R:R:F292	R:R:I289	3.77	No	No	0	1	4
181	R:R:D295	R:R:K293	12.44	No	No	0	3	1
182	R:R:D295	R:R:V297	14.61	No	No	0	3	4
183	R:R:S301	R:R:W305	3.71	No	No	0	2	4
184	R:R:F303	R:R:V307	3.93	Yes	No	1	4	5
185	R:R:F311	R:R:V307	3.93	Yes	No	0	7	5
186	R:R:N313	R:R:N317	9.54	No	No	0	9	9
187	R:R:N322	R:R:T324	4.39	Yes	No	3	7	7
188	R:R:G57	R:R:L56	3.42	No	No	0	9	4
189	R:R:C76	R:R:V78	3.42	No	No	0	5	8
190	R:R:A84	R:R:V124	3.39	No	Yes	0	8	7
191	R:R:I92	R:R:P93	3.39	Yes	No	0	7	9
192	R:R:I126	R:R:P219	3.39	No	No	0	8	9
193	R:R:A130	R:R:V222	3.39	No	No	0	7	6
194	R:R:I201	R:R:P202	3.39	No	No	0	4	3
195	R:R:A170	R:R:T119	3.36	No	Yes	0	7	5
196	R:R:S314	R:R:S54	3.26	No	No	0	9	8
197	R:R:S192	R:R:V179	3.23	No	No	0	3	5
198	R:R:A91	R:R:M118	3.22	No	Yes	0	6	7
199	R:R:R70	R:R:R71	3.2	No	No	0	7	7
200	R:R:R261	R:R:R264	3.2	No	No	0	8	7
201	R:R:C60	R:R:L56	3.17	No	No	0	6	4
202	R:R:T195	R:R:V180	3.17	No	No	0	4	4
203	R:R:A110	R:R:L113	3.15	No	No	0	5	5
204	R:R:I50	R:R:V46	3.07	No	No	0	7	6
205	R:R:M270	R:R:V224	3.04	No	No	0	8	5
206	R:R:F88	R:R:G122	3.01	Yes	No	0	7	7
207	R:R:F274	R:R:G220	3.01	No	No	0	6	6
208	R:R:M323	R:R:T265	3.01	No	No	0	5	8
209	R:R:R36	R:R:W100	3	No	No	0	4	5
210	R:R:L120	R:R:S166	3	No	No	0	5	8
211	R:R:L134	R:R:S226	3	No	No	0	5	5
212	R:R:L55	R:R:V59	2.98	No	No	0	5	3
213	R:R:L87	R:R:V117	2.98	No	No	0	6	4
214	R:R:L302	R:R:V306	2.98	No	No	0	5	6
215	R:R:N322	R:R:V65	2.96	Yes	No	0	7	7
216	R:R:L49	R:R:T45	2.95	No	No	0	4	4
217	R:R:L214	R:R:T213	2.95	No	No	0	4	5
218	R:R:I201	R:R:I205	2.94	No	No	0	4	4
219	R:R:Q290	R:R:V297	2.87	No	No	0	4	4
220	R:R:I89	R:R:L55	2.85	Yes	No	0	6	5
221	R:R:I162	R:R:L127	2.85	No	No	0	7	6
222	R:R:I230	R:R:L266	2.85	No	No	0	8	8
223	R:R:I319	R:R:L320	2.85	No	No	0	7	8
224	R:R:Q252	R:R:T242	2.83	No	No	0	2	4
225	R:R:K32	R:R:L39	2.82	Yes	No	0	3	4
226	R:R:H142	R:R:V141	2.77	No	No	0	5	6
227	R:R:A169	R:R:F211	2.77	No	Yes	0	5	5
228	R:R:L268	R:R:L320	2.77	No	No	0	6	8
229	R:R:E102	R:R:I191	2.73	No	No	0	4	4
230	R:R:A40	R:R:W100	2.59	No	No	0	5	5
231	R:R:F303	R:R:T283	2.59	Yes	No	0	4	5
232	R:R:I197	R:R:R178	2.51	No	No	0	4	4
233	R:R:F309	R:R:M276	2.49	No	Yes	0	7	8
234	R:R:F216	R:R:L217	2.44	Yes	No	0	8	4
235	R:R:F263	R:R:L231	2.44	No	No	0	7	6
236	R:R:T101	R:R:W100	2.43	No	No	0	4	5
237	R:R:L302	R:R:W299	2.28	No	No	0	5	4
238	R:R:F263	R:R:F267	2.14	No	No	0	7	5
239	R:R:R183	R:R:R24	2.13	Yes	No	0	3	5
240	R:R:R68	R:R:R71	2.13	No	No	0	6	7
241	R:R:F176	R:R:W198	2	No	Yes	0	5	7
242	R:R:A73	R:R:G72	1.95	No	No	0	6	7
243	R:R:A154	R:R:G151	1.95	No	No	0	5	7
244	R:R:A167	R:R:G164	1.95	No	No	0	3	4
245	R:R:G203	R:R:T200	1.82	No	No	0	3	3
246	R:R:P279	R:R:V306	1.77	No	No	0	9	6
247	R:R:P199	R:R:T200	1.75	No	No	0	6	3
248	R:R:A315	R:R:S54	1.71	No	No	0	6	8
249	R:R:C60	R:R:V59	1.71	No	No	0	6	3
250	R:R:C111	R:R:V179	1.71	No	No	0	9	5
251	R:R:A315	R:R:V53	1.7	No	No	0	6	5
252	R:R:A312	R:R:I50	1.62	No	No	0	5	7
253	R:R:A103	R:R:I191	1.62	No	No	0	5	4
254	R:R:T44	R:R:V48	1.59	No	No	0	6	4
255	R:R:A308	R:R:L47	1.58	No	Yes	0	4	6
256	R:R:A131	R:R:L77	1.58	No	No	0	7	7
257	R:R:A167	R:R:L120	1.58	No	No	0	3	5
258	R:R:A246	R:R:L241	1.58	No	No	0	4	5
259	R:R:C83	R:R:N80	1.57	No	Yes	0	5	9
260	R:R:I233	R:R:V141	1.54	No	No	0	5	6
261	R:R:I205	R:R:V209	1.54	No	No	0	4	4
262	R:R:K229	R:R:S228	1.53	Yes	No	0	5	3
263	R:R:M137	R:R:V141	1.52	No	No	0	8	6
264	R:R:L37	R:R:V38	1.49	No	No	0	3	3
265	R:R:D259	R:R:V255	1.46	No	No	0	7	5
266	R:R:I275	R:R:M276	1.46	No	Yes	0	5	8
267	R:R:D259	R:R:T234	1.45	No	No	0	7	8
268	R:R:H251	R:R:S248	1.39	Yes	No	0	2	6
269	R:R:H35	R:R:V38	1.38	No	No	0	3	3
270	R:R:H142	R:R:V138	1.38	No	No	0	5	4
271	R:R:L158	R:R:L161	1.38	No	No	0	5	2
272	R:R:I191	R:R:Q182	1.37	No	No	0	4	2
273	R:R:I253	R:R:Q257	1.37	No	No	0	3	5
274	R:R:R254	R:R:S250	1.32	No	No	0	4	5
275	R:R:L79	R:R:R69	1.21	No	No	0	5	7
276	R:R:Q258	R:R:R254	1.17	No	No	0	6	4

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:?1	5.86	10	1	0
2	R:R:F25	6.365	6	0	5
3	R:R:F27	7.115	4	1	5
4	R:R:F28	7.078	5	1	8
5	R:R:K32	4.7475	4	5	3
6	R:R:L47	4.7175	4	0	6
7	R:R:N58	10.4275	4	3	9
8	R:R:N80	6.49	5	7	9
9	R:R:F82	5.185	6	3	9
10	R:R:F88	6.04	4	0	7
11	R:R:I89	6.0775	4	6	6
12	R:R:I92	6.48	5	6	7
13	R:R:W104	8.98	5	4	9
14	R:R:F115	6.27	4	1	5
15	R:R:M118	4.5025	4	0	7
16	R:R:T119	4.1025	4	1	5
17	R:R:V124	7.765	4	7	7
18	R:R:R136	5.265	4	2	9
19	R:R:F177	7.7075	4	1	5
20	R:R:R183	5.1175	4	0	3
21	R:R:W198	15.4875	4	0	7
22	R:R:W207	9.244	5	0	6
23	R:R:D208	7.4275	4	1	5
24	R:R:F211	5.648	5	1	5
25	R:R:N215	8.0075	4	0	6
26	R:R:F216	6.4575	4	0	8
27	R:R:Y227	5.20571	7	2	9
28	R:R:K229	5.625	4	0	5
29	R:R:Y247	6.6425	4	9	4
30	R:R:H251	4.9625	4	9	2
31	R:R:F273	4.844	5	2	9
32	R:R:M276	5.084	5	0	8
33	R:R:W277	10.205	4	2	9
34	R:R:F303	4.5775	4	1	4
35	R:R:F311	7.4675	4	0	7
36	R:R:Y321	4.87	5	2	9
37	R:R:N322	4.075	4	3	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:F27	28.6794	4.89	Yes	Yes	1	0	5
2	R:R:F25	R:R:F27	21.5362	7.5	Yes	Yes	0	5	5
3	R:R:F25	R:R:P26	30.9523	4.33	Yes	No	0	5	5
4	R:R:P26	R:R:R183	17.5638	4.32	No	Yes	0	5	3
5	L:L:?1	R:R:I287	20.3744	4.59	Yes	No	0	0	5
6	R:R:F25	R:R:I287	19.4612	5.02	Yes	No	0	5	5
7	R:R:R183	R:R:R24	12.9572	2.13	Yes	No	0	3	5
8	R:R:P26	R:R:S29	11.8056	5.34	No	No	0	5	9
9	L:L:?1	R:R:F88	33.6411	4.89	Yes	Yes	0	0	7
10	R:R:F311	R:R:F88	29.9376	9.65	Yes	Yes	0	7	7
11	L:L:?1	R:R:M118	31.3378	6.82	Yes	Yes	0	0	7
12	R:R:F311	R:R:M118	29.8463	3.73	Yes	Yes	0	7	7
13	R:R:F311	R:R:I92	63.5077	12.56	Yes	Yes	0	7	7
14	R:R:I92	R:R:L47	43.9856	4.28	Yes	Yes	0	7	6
15	R:R:F304	R:R:L47	36.0154	6.09	No	Yes	0	4	6
16	R:R:F304	R:R:R99	24.2301	27.79	No	No	0	4	4
17	R:R:K32	R:R:R99	20.9375	7.43	Yes	No	5	3	4
18	R:R:K32	R:R:L39	16.1585	2.82	Yes	No	0	3	4
19	R:R:D34	R:R:L39	14.4031	6.79	No	No	0	3	4
20	R:R:D34	R:R:H35	12.6376	3.78	No	No	0	3	3
21	R:R:H35	R:R:V38	10.862	1.38	No	No	0	3	3
22	R:R:E43	R:R:F304	10.5068	9.33	No	No	0	5	4
23	R:R:I89	R:R:I92	17.7515	5.89	Yes	Yes	6	6	7
24	L:L:?1	R:R:I280	96.6465	8.03	Yes	No	1	0	6
25	R:R:I280	R:R:T310	100	4.56	No	No	0	6	8
26	R:R:T310	R:R:W277	99.4064	3.64	No	Yes	0	8	9
27	R:R:F273	R:R:W277	88.098	5.01	Yes	Yes	2	9	9
28	R:R:F273	R:R:L129	82.1166	3.65	Yes	No	2	9	8
29	R:R:L129	R:R:Y321	62.1125	7.03	No	Yes	2	8	9
30	R:R:R136	R:R:Y321	27.3046	5.14	Yes	Yes	2	9	9
31	R:R:E135	R:R:R136	27.8525	3.49	No	Yes	0	8	9
32	R:R:C76	R:R:E135	26.4776	6.08	No	No	0	5	8
33	R:R:C76	R:R:V78	25.0926	3.42	No	No	0	5	8
34	R:R:F82	R:R:V78	23.6974	3.93	Yes	No	0	9	8
35	R:R:F82	R:R:N322	13.6472	4.83	Yes	Yes	3	9	7
36	R:R:L129	R:R:L81	19.1517	5.54	No	No	2	8	9
37	R:R:L81	R:R:T128	21.9877	4.42	No	No	0	9	8
38	R:R:N80	R:R:T128	20.5926	8.77	Yes	No	0	9	8
39	R:R:N80	R:R:V124	11.9679	4.43	Yes	Yes	7	9	7
40	R:R:C111	R:R:W104	11.2069	5.22	No	Yes	4	9	9
41	L:L:?1	R:R:F211	15.7476	4.89	Yes	Yes	1	0	5
42	R:R:F211	R:R:N215	10.4003	9.67	Yes	Yes	0	5	6
43	R:R:Y227	R:R:Y321	33.2961	3.97	Yes	Yes	2	9	9
44	R:R:S133	R:R:Y227	21.8406	5.09	No	Yes	2	8	9
45	R:R:S133	R:R:S226	20.5215	6.52	No	No	0	8	5
46	R:R:M137	R:R:S226	14.8394	9.2	No	No	0	8	5
47	R:R:L266	R:R:Y227	10.5423	4.69	No	Yes	0	8	9
48	L:L:?1	R:R:E204	15.7729	4.26	Yes	No	0	0	5
49	R:R:E204	R:R:W198	13.1247	31.62	No	Yes	0	5	7
50	R:R:F176	R:R:W198	13.8755	2	No	Yes	0	5	7
51	R:R:F176	R:R:P199	10.862	7.22	No	No	0	5	6
52	R:R:N313	R:R:W277	16.3462	18.08	No	Yes	0	9	9
53	R:R:M276	R:R:N313	13.4646	11.22	Yes	No	0	8	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?1	R:R:F27	4.89	1	Yes	Yes	0	5	0	1
L:L:?1	R:R:F88	4.89	1	Yes	Yes	0	7	0	1
L:L:?1	R:R:M118	6.82	1	Yes	Yes	0	7	0	1
L:L:?1	R:R:T119	4.74	1	Yes	Yes	0	5	0	1
L:L:?1	R:R:E204	4.26	1	Yes	No	0	5	0	1
L:L:?1	R:R:D208	10.9	1	Yes	Yes	0	5	0	1
L:L:?1	R:R:F211	4.89	1	Yes	Yes	0	5	0	1
L:L:?1	R:R:I280	8.03	1	Yes	No	0	6	0	1
L:L:?1	R:R:I284	4.59	1	Yes	No	0	5	0	1
L:L:?1	R:R:I287	4.59	1	Yes	No	0	5	0	1
R:R:F25	R:R:F27	7.5	0	Yes	Yes	5	5	2	1
R:R:F25	R:R:I287	5.02	0	Yes	No	5	5	2	1
R:R:F115	R:R:F27	8.57	1	Yes	Yes	5	5	2	1
R:R:F177	R:R:F27	7.5	1	Yes	Yes	5	5	2	1
R:R:F88	R:R:S121	6.61	0	Yes	No	7	8	1	2
R:R:F311	R:R:F88	9.65	0	Yes	Yes	7	7	2	1
R:R:F115	R:R:L114	3.65	1	Yes	No	5	6	2	2
R:R:L114	R:R:M118	4.24	0	No	Yes	6	7	2	1
R:R:F115	R:R:F177	7.5	1	Yes	Yes	5	5	2	2
R:R:F311	R:R:M118	3.73	0	Yes	Yes	7	7	2	1
R:R:L173	R:R:T119	4.42	0	No	Yes	5	5	2	1
R:R:F211	R:R:T119	3.89	1	Yes	Yes	5	5	1	1
R:R:F177	R:R:L173	3.65	1	Yes	No	5	5	2	2
R:R:L173	R:R:W207	7.97	0	No	Yes	5	6	2	2
R:R:E204	R:R:W198	31.62	0	No	Yes	5	7	1	2
R:R:W198	R:R:W207	11.25	0	Yes	Yes	7	6	2	2
R:R:E204	R:R:N291	9.2	0	No	No	5	2	1	2
R:R:D208	R:R:W207	7.82	1	Yes	Yes	5	6	1	2
R:R:F211	R:R:W207	7.02	1	Yes	Yes	5	6	1	2
R:R:D208	R:R:I284	4.2	1	Yes	No	5	5	1	1
R:R:D208	R:R:L288	6.79	1	Yes	No	5	4	1	2
R:R:F211	R:R:N215	9.67	1	Yes	Yes	5	6	1	2
R:R:I280	R:R:I284	4.42	1	No	No	6	5	1	1
R:R:I280	R:R:T310	4.56	1	No	No	6	8	1	2
R:R:A170	R:R:T119	3.36	0	No	Yes	7	5	2	1
R:R:A91	R:R:M118	3.22	0	No	Yes	6	7	2	1
R:R:F88	R:R:G122	3.01	0	Yes	No	7	7	1	2
R:R:A169	R:R:F211	2.77	0	No	Yes	5	5	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	8ID4_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.49
Number of Linked Nodes	256
Number of Links	276
Number of Hubs	37
Number of Links mediated by Hubs	138
Number of Communities	9
Number of Nodes involved in Communities	49
Number of Links involved in Communities	59

Path Summary
Number Of Nodes in MetaPath	54
Number Of Links MetaPath	53
Number of Shortest Paths	35393
Length Of Smallest Path	3
Average Path Length	12.9573
Length of Longest Path	32
Minimum Path Strength	1.245
Average Path Strength	6.15225
Maximum Path Strength	24.35
Minimum Path Correlation	0.7
Average Path Correlation	0.943215
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	5
Average % Of Corr. Nodes	63.014
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	46.762
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain • Ras-like P-loop GTPases
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain • Ras-like P-loop GTPases
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	EIC
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	EIC
Name	Linoleic acid
Synonyms	Sodium linolate
Identifier
Formula	C18 H32 O2
Molecular Weight	280.445
SMILES
PubChem	5280450
Formal Charge	0
Total Atoms	52
Total Chiral Atoms	0
Total Bonds	51
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q5NUL3
Sequence	>8ID4_nogp_Chain_R T R F P F F S D V K G D H R L V L A A V E T T V L V L I F A V S L L G N V C A L V L V A R R R R R G A C L V L N L F C A D L L F I S A I P L V L A V R W T E A W G P V A C H L L F Y V M T L S G S V T I L T L A A V S L E R M V C I V H L G R R A R A V L L A L I W G Y S A V A A L P L C V F F R V V P Q R I S I C T L I W P T I P G E I S W D V S F V T L N F L V P G L V I V I S Y S K I L Q I T K A S R K R L T V S L A Y S E S H Q I R V S Q Q D F R L F R T L F L L M V S F F I M W S P I I I T I L L I L I Q N F K Q D L V I W P S L F F W V V A F T F A N S A L N P I L Y N M T L Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8G59	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	TUG-891	-	chim(Gi1-CtGq)/β1/γ2	2.64	2023-03-08	doi.org/10.1126/science.add6220
	8G59 (No Gprot)	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	TUG-891	-		2.64	2023-03-08	doi.org/10.1126/science.add6220
	8ID3	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	9-Hydroxystearic acid	-	Gi1/β1/γ2	3.1	2023-03-15	doi.org/10.1126/science.add6220
	8ID3 (No Gprot)	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	9-Hydroxystearic acid	-		3.1	2023-03-15	doi.org/10.1126/science.add6220
	8ID4	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	Linoleic acid	-	Gi1/β1/γ2	3.1	2023-03-15	doi.org/10.1126/science.add6220
	8ID4 (No Gprot)	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	Linoleic acid	-		3.1	2023-03-15	doi.org/10.1126/science.add6220
	8ID6	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	Oleic acid	-	Gi1/β1/γ2	2.8	2023-03-15	doi.org/10.1126/science.add6220
	8ID6 (No Gprot)	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	Oleic acid	-		2.8	2023-03-15	doi.org/10.1126/science.add6220
	8ID8	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	TUG-891	-	Gi1/β1/γ2	3	2023-03-15	doi.org/10.1126/science.add6220
	8ID8 (No Gprot)	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	TUG-891	-		3	2023-03-15	doi.org/10.1126/science.add6220
	8ID9	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	Icosapent	-	Gi1/β1/γ2	3	2023-03-15	doi.org/10.1126/science.add6220
	8ID9 (No Gprot)	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	Icosapent	-		3	2023-03-15	doi.org/10.1126/science.add6220
	8H4I	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	Doconexent	-	chim(NtGi1-Gs)/β1/γ2	3.06	2023-06-21	doi.org/10.1038/s41422-023-00835-x
	8H4I (No Gprot)	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	Doconexent	-		3.06	2023-06-21	doi.org/10.1038/s41422-023-00835-x
	8H4K	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	GW9508	-	chim(NtGi1-Gs-CtGq)/β1/γ2	3.1	2023-06-21	doi.org/10.1038/s41422-023-00835-x
	8H4K (No Gprot)	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	GW9508	-		3.1	2023-06-21	doi.org/10.1038/s41422-023-00835-x
	8H4L	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	Doconexent	-	chim(NtGi1-Gs-CtGq)/β1/γ2	3.07	2023-06-21	doi.org/10.1038/s41422-023-00835-x
	8H4L (No Gprot)	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	Doconexent	-		3.07	2023-06-21	doi.org/10.1038/s41422-023-00835-x
	8IYS	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	TUG-891	GDP	chim(NtGi1L-Gq)/β1/γ2	2.95	2023-06-21	doi.org/10.1038/s41422-023-00835-x
	8IYS (No Gprot)	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	TUG-891	GDP		2.95	2023-06-21	doi.org/10.1038/s41422-023-00835-x
	8T3O	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	TUG-891	-	chim(NtGi2L-Gs-CtGq)/β1/γ2	3.06	2024-01-17	doi.org/10.1126/sciadv.adj2384
	8T3O (No Gprot)	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	TUG-891	-		3.06	2024-01-17	doi.org/10.1126/sciadv.adj2384
	8T3Q	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	Doconexent	-	chim(NtGi2L-Gs-CtGq)/β1/γ2	3.14	2024-01-24	doi.org/10.1126/sciadv.adj2384
	8T3Q (No Gprot)	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	Doconexent	-		3.14	2024-01-24	doi.org/10.1126/sciadv.adj2384

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 8ID4_nogp.zip

You can click to copy the link of this page to easily come back here later

or use this QR code to link and share this page.

You can also read or download a guide explaining the meaning of all files and numerical data.