psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:F27	4.89	Yes	Yes	1	0	5
2	L:L:?1	R:R:F88	4.89	Yes	Yes	0	0	7
3	L:L:?1	R:R:M118	6.82	Yes	Yes	0	0	7
4	L:L:?1	R:R:T119	4.74	Yes	Yes	1	0	5
5	L:L:?1	R:R:E204	4.26	Yes	No	0	0	5
6	L:L:?1	R:R:D208	10.9	Yes	Yes	1	0	5
7	L:L:?1	R:R:F211	4.89	Yes	Yes	1	0	5
8	L:L:?1	R:R:I280	8.03	Yes	No	1	0	6
9	L:L:?1	R:R:I284	4.59	Yes	No	1	0	5
10	L:L:?1	R:R:I287	4.59	Yes	No	0	0	5
11	R:R:R183	R:R:T23	7.76	Yes	No	0	3	8
12	R:R:R24	R:R:T195	6.47	No	No	0	5	4
13	R:R:I197	R:R:R24	3.76	No	No	0	4	5
14	R:R:F25	R:R:P26	4.33	Yes	No	0	5	5
15	R:R:F25	R:R:F27	7.5	Yes	Yes	0	5	5
16	R:R:F25	R:R:I287	5.02	Yes	No	0	5	5
17	R:R:F25	R:R:Q290	4.68	Yes	No	0	5	4
18	R:R:F25	R:R:I298	11.3	Yes	No	0	5	3
19	R:R:F25	R:R:F303	5.36	Yes	Yes	0	5	4
20	R:R:P26	R:R:S29	5.34	No	No	0	5	9
21	R:R:P26	R:R:R183	4.32	No	Yes	0	5	3
22	R:R:F115	R:R:F27	8.57	Yes	Yes	1	5	5
23	R:R:F177	R:R:F27	7.5	Yes	Yes	1	5	5
24	R:R:F28	R:R:V95	11.8	Yes	No	0	8	6
25	R:R:F28	R:R:V98	3.93	Yes	No	0	8	5
26	R:R:F115	R:R:F28	5.36	Yes	Yes	1	5	8
27	R:R:F28	R:R:F303	6.43	Yes	Yes	1	8	4
28	R:R:F28	R:R:V307	7.87	Yes	No	1	8	5
29	R:R:S29	R:R:W104	9.88	No	Yes	4	9	9
30	R:R:I193	R:R:S29	4.64	No	No	4	4	9
31	R:R:D30	R:R:K32	4.15	No	Yes	0	6	3
32	R:R:D30	R:R:P300	4.83	No	No	0	6	4
33	R:R:K32	R:R:R99	7.43	Yes	No	5	3	4
34	R:R:K32	R:R:S301	4.59	Yes	No	5	3	2
35	R:R:D34	R:R:H35	3.78	No	No	0	3	3
36	R:R:D34	R:R:L39	6.79	No	No	0	3	4
37	R:R:L37	R:R:R36	4.86	No	No	0	3	4
38	R:R:E43	R:R:V42	5.7	No	No	0	5	5
39	R:R:E43	R:R:F304	9.33	No	No	0	5	4
40	R:R:E43	R:R:W305	15.27	No	No	0	5	4
41	R:R:L96	R:R:T44	5.9	No	No	0	6	6
42	R:R:V46	R:R:W305	4.9	No	No	0	6	4
43	R:R:I92	R:R:L47	4.28	Yes	Yes	0	7	6
44	R:R:L47	R:R:L96	6.92	Yes	No	0	6	6
45	R:R:F304	R:R:L47	6.09	No	Yes	0	4	6
46	R:R:F51	R:R:I89	6.28	No	Yes	6	6	6
47	R:R:F51	R:R:I92	6.28	No	Yes	6	6	7
48	R:R:I89	R:R:S54	9.29	Yes	No	0	6	8
49	R:R:F82	R:R:N58	4.83	Yes	Yes	3	9	9
50	R:R:D85	R:R:N58	17.5	No	Yes	0	9	9
51	R:R:L86	R:R:N58	9.61	No	Yes	0	7	9
52	R:R:N58	R:R:P318	9.77	Yes	No	3	9	9
53	R:R:A61	R:R:F82	8.32	No	Yes	0	8	9
54	R:R:F82	R:R:L62	4.87	Yes	No	0	9	6
55	R:R:R67	R:R:V63	3.92	No	No	0	6	4
56	R:R:L64	R:R:N322	4.12	No	Yes	3	7	7
57	R:R:L64	R:R:T324	7.37	No	No	3	7	7
58	R:R:L79	R:R:V65	5.96	No	No	0	5	7
59	R:R:R68	R:R:T324	6.47	No	No	0	6	7
60	R:R:C76	R:R:E135	6.08	No	No	0	5	8
61	R:R:L159	R:R:L77	4.15	No	No	0	7	7
62	R:R:F82	R:R:V78	3.93	Yes	No	0	9	8
63	R:R:N80	R:R:V124	4.43	Yes	Yes	7	9	7
64	R:R:N80	R:R:T128	8.77	Yes	No	0	9	8
65	R:R:L159	R:R:N80	4.12	No	Yes	0	7	9
66	R:R:N80	R:R:W163	13.56	Yes	No	7	9	9
67	R:R:L81	R:R:T128	4.42	No	No	0	9	8
68	R:R:L129	R:R:L81	5.54	No	No	2	8	9
69	R:R:L81	R:R:Y321	3.52	No	Yes	2	9	9
70	R:R:F82	R:R:P318	4.33	Yes	No	3	9	9
71	R:R:F82	R:R:N322	4.83	Yes	Yes	3	9	7
72	R:R:L87	R:R:S121	9.01	No	No	0	6	8
73	R:R:F88	R:R:S121	6.61	Yes	No	0	7	8
74	R:R:F311	R:R:F88	9.65	Yes	Yes	0	7	7
75	R:R:I89	R:R:I92	5.89	Yes	Yes	6	6	7
76	R:R:F311	R:R:I92	12.56	Yes	Yes	0	7	7
77	R:R:L114	R:R:L94	6.92	No	No	0	6	5
78	R:R:V98	R:R:W104	13.48	No	Yes	0	5	9
79	R:R:R99	R:R:S301	3.95	No	No	5	4	2
80	R:R:F304	R:R:R99	27.79	No	No	0	4	4
81	R:R:C111	R:R:W104	5.22	No	Yes	4	9	9
82	R:R:I193	R:R:W104	5.87	No	Yes	4	4	9
83	R:R:C194	R:R:W104	10.45	No	Yes	4	9	9
84	R:R:G107	R:R:P108	4.06	No	No	0	8	3
85	R:R:P108	R:R:V179	5.3	No	No	0	3	5
86	R:R:C111	R:R:C194	7.28	No	No	4	9	9
87	R:R:H112	R:R:R178	4.51	No	No	0	7	4
88	R:R:F115	R:R:L114	3.65	Yes	No	0	5	6
89	R:R:L114	R:R:M118	4.24	No	Yes	0	6	7
90	R:R:F115	R:R:F177	7.5	Yes	Yes	1	5	5
91	R:R:L120	R:R:Y116	4.69	No	No	0	5	5
92	R:R:C174	R:R:Y116	9.41	No	No	0	4	5
93	R:R:F311	R:R:M118	3.73	Yes	Yes	0	7	7
94	R:R:L173	R:R:T119	4.42	No	Yes	0	5	5
95	R:R:F211	R:R:T119	3.89	Yes	Yes	1	5	5
96	R:R:G122	R:R:T125	3.64	No	No	0	7	9
97	R:R:N215	R:R:S123	8.94	Yes	No	0	6	6
98	R:R:V124	R:R:W163	18.39	Yes	No	7	7	9
99	R:R:S166	R:R:V124	4.85	No	Yes	0	8	7
100	R:R:F273	R:R:I126	3.77	Yes	No	2	9	8
101	R:R:I126	R:R:W277	14.09	No	Yes	2	8	9
102	R:R:L127	R:R:N215	4.12	No	Yes	0	6	6
103	R:R:F273	R:R:L129	3.65	Yes	No	2	9	8
104	R:R:L129	R:R:Y321	7.03	No	Yes	2	8	9
105	R:R:R136	R:R:V132	5.23	Yes	No	0	9	8
106	R:R:I223	R:R:S133	6.19	No	No	2	8	8
107	R:R:S133	R:R:S226	6.52	No	No	0	8	5
108	R:R:S133	R:R:Y227	5.09	No	Yes	2	8	9
109	R:R:L134	R:R:V222	4.47	No	No	0	5	6
110	R:R:E135	R:R:R136	3.49	No	Yes	0	8	9
111	R:R:R136	R:R:Y227	7.2	Yes	Yes	2	9	9
112	R:R:R136	R:R:Y321	5.14	Yes	Yes	2	9	9
113	R:R:M137	R:R:S226	9.2	No	No	0	8	5
114	R:R:K229	R:R:M137	5.76	Yes	No	0	5	8
115	R:R:I140	R:R:I230	4.42	No	No	0	8	8
116	R:R:L214	R:R:Y165	7.03	No	No	0	4	4
117	R:R:N215	R:R:Y165	9.3	Yes	No	0	6	4
118	R:R:L171	R:R:P172	4.93	No	No	0	5	8
119	R:R:P172	R:R:W207	12.16	No	Yes	0	8	6
120	R:R:F177	R:R:L173	3.65	Yes	No	0	5	5
121	R:R:L173	R:R:W207	7.97	No	Yes	0	5	6
122	R:R:F176	R:R:V175	3.93	No	No	0	5	4
123	R:R:F176	R:R:P199	7.22	No	No	0	5	6
124	R:R:F177	R:R:L196	12.18	Yes	No	0	5	5
125	R:R:P181	R:R:V180	5.3	No	No	0	2	4
126	R:R:I193	R:R:R183	6.26	No	Yes	0	4	3
127	R:R:L196	R:R:W198	17.08	No	Yes	0	5	7
128	R:R:E204	R:R:W198	31.62	No	Yes	0	5	7
129	R:R:W198	R:R:W207	11.25	Yes	Yes	0	7	6
130	R:R:P202	R:R:T200	3.5	No	No	0	3	3
131	R:R:E204	R:R:N291	9.2	No	No	0	5	2
132	R:R:D208	R:R:W207	7.82	Yes	Yes	0	5	6
133	R:R:F211	R:R:W207	7.02	Yes	Yes	0	5	6
134	R:R:D208	R:R:I284	4.2	Yes	No	1	5	5
135	R:R:D208	R:R:L288	6.79	Yes	No	0	5	4
136	R:R:F211	R:R:N215	9.67	Yes	Yes	0	5	6
137	R:R:I281	R:R:V212	4.61	No	No	0	7	6
138	R:R:L285	R:R:V212	4.47	No	No	0	6	6
139	R:R:F216	R:R:F273	4.29	Yes	Yes	0	8	9
140	R:R:F216	R:R:S278	5.28	Yes	No	0	8	7
141	R:R:F216	R:R:I281	13.82	Yes	No	0	8	7
142	R:R:P219	R:R:V218	3.53	No	No	0	9	5
143	R:R:I225	R:R:L221	7.14	No	No	0	4	2
144	R:R:I223	R:R:Y227	4.84	No	Yes	2	8	9
145	R:R:I225	R:R:K229	4.36	No	Yes	0	4	5
146	R:R:L266	R:R:Y227	4.69	No	Yes	0	8	9
147	R:R:L269	R:R:Y227	5.86	No	Yes	2	8	9
148	R:R:M270	R:R:Y227	4.79	No	Yes	0	8	9
149	R:R:Y227	R:R:Y321	3.97	Yes	Yes	2	9	9
150	R:R:K229	R:R:Q232	10.85	Yes	No	0	5	4
151	R:R:L231	R:R:L266	11.07	No	No	0	6	8
152	R:R:L262	R:R:T234	4.42	No	No	0	8	8
153	R:R:K235	R:R:R238	4.95	No	No	8	5	4
154	R:R:K235	R:R:K239	8.62	No	No	8	5	5
155	R:R:R240	R:R:S237	3.95	No	No	0	3	6
156	R:R:K239	R:R:R238	13.61	No	No	8	5	4
157	R:R:D259	R:R:R238	11.91	No	No	0	7	4
158	R:R:L241	R:R:Y247	4.69	No	Yes	0	5	4
159	R:R:H251	R:R:Y247	9.8	Yes	Yes	9	2	4
160	R:R:Q252	R:R:Y247	4.51	No	Yes	0	2	4
161	R:R:V255	R:R:Y247	7.57	No	Yes	9	5	4
162	R:R:H251	R:R:R254	4.51	Yes	No	0	2	4
163	R:R:H251	R:R:V255	4.15	Yes	No	9	2	5
164	R:R:R264	R:R:T265	3.88	No	No	0	7	8
165	R:R:F267	R:R:V271	9.18	No	No	0	5	5
166	R:R:L269	R:R:L320	4.15	No	No	0	8	8
167	R:R:L269	R:R:Y321	4.69	No	Yes	2	8	9
168	R:R:M276	R:R:S272	4.6	Yes	No	0	8	6
169	R:R:F273	R:R:F274	7.5	Yes	No	0	9	6
170	R:R:F273	R:R:W277	5.01	Yes	Yes	2	9	9
171	R:R:M276	R:R:N313	11.22	Yes	No	0	8	9
172	R:R:L316	R:R:M276	5.65	No	Yes	0	6	8
173	R:R:T310	R:R:W277	3.64	No	Yes	0	8	9
174	R:R:N313	R:R:W277	18.08	No	Yes	0	9	9
175	R:R:F309	R:R:P279	10.11	No	No	0	7	9
176	R:R:I280	R:R:I284	4.42	No	No	1	6	5
177	R:R:I280	R:R:T310	4.56	No	No	0	6	8
178	R:R:L286	R:R:V297	4.47	No	No	0	5	4
179	R:R:F292	R:R:L288	4.87	No	No	0	1	4
180	R:R:F292	R:R:I289	3.77	No	No	0	1	4
181	R:R:D295	R:R:K293	12.44	No	No	0	3	1
182	R:R:D295	R:R:V297	14.61	No	No	0	3	4
183	R:R:S301	R:R:W305	3.71	No	No	0	2	4
184	R:R:F303	R:R:V307	3.93	Yes	No	1	4	5
185	R:R:F311	R:R:V307	3.93	Yes	No	0	7	5
186	R:R:N313	R:R:N317	9.54	No	No	0	9	9
187	R:R:N322	R:R:T324	4.39	Yes	No	3	7	7
188	R:R:G57	R:R:L56	3.42	No	No	0	9	4
189	R:R:C76	R:R:V78	3.42	No	No	0	5	8
190	R:R:A84	R:R:V124	3.39	No	Yes	0	8	7
191	R:R:I92	R:R:P93	3.39	Yes	No	0	7	9
192	R:R:I126	R:R:P219	3.39	No	No	0	8	9
193	R:R:A130	R:R:V222	3.39	No	No	0	7	6
194	R:R:I201	R:R:P202	3.39	No	No	0	4	3
195	R:R:A170	R:R:T119	3.36	No	Yes	0	7	5
196	R:R:S314	R:R:S54	3.26	No	No	0	9	8
197	R:R:S192	R:R:V179	3.23	No	No	0	3	5
198	R:R:A91	R:R:M118	3.22	No	Yes	0	6	7
199	R:R:R70	R:R:R71	3.2	No	No	0	7	7
200	R:R:R261	R:R:R264	3.2	No	No	0	8	7
201	R:R:C60	R:R:L56	3.17	No	No	0	6	4
202	R:R:T195	R:R:V180	3.17	No	No	0	4	4
203	R:R:A110	R:R:L113	3.15	No	No	0	5	5
204	R:R:I50	R:R:V46	3.07	No	No	0	7	6
205	R:R:M270	R:R:V224	3.04	No	No	0	8	5
206	R:R:F88	R:R:G122	3.01	Yes	No	0	7	7
207	R:R:F274	R:R:G220	3.01	No	No	0	6	6
208	R:R:M323	R:R:T265	3.01	No	No	0	5	8
209	R:R:R36	R:R:W100	3	No	No	0	4	5
210	R:R:L120	R:R:S166	3	No	No	0	5	8
211	R:R:L134	R:R:S226	3	No	No	0	5	5
212	R:R:L55	R:R:V59	2.98	No	No	0	5	3
213	R:R:L87	R:R:V117	2.98	No	No	0	6	4
214	R:R:L302	R:R:V306	2.98	No	No	0	5	6
215	R:R:N322	R:R:V65	2.96	Yes	No	0	7	7
216	R:R:L49	R:R:T45	2.95	No	No	0	4	4
217	R:R:L214	R:R:T213	2.95	No	No	0	4	5
218	R:R:I201	R:R:I205	2.94	No	No	0	4	4
219	R:R:Q290	R:R:V297	2.87	No	No	0	4	4
220	R:R:I89	R:R:L55	2.85	Yes	No	0	6	5
221	R:R:I162	R:R:L127	2.85	No	No	0	7	6
222	R:R:I230	R:R:L266	2.85	No	No	0	8	8
223	R:R:I319	R:R:L320	2.85	No	No	0	7	8
224	R:R:Q252	R:R:T242	2.83	No	No	0	2	4
225	R:R:K32	R:R:L39	2.82	Yes	No	0	3	4
226	R:R:H142	R:R:V141	2.77	No	No	0	5	6
227	R:R:A169	R:R:F211	2.77	No	Yes	0	5	5
228	R:R:L268	R:R:L320	2.77	No	No	0	6	8
229	R:R:E102	R:R:I191	2.73	No	No	0	4	4
230	R:R:A40	R:R:W100	2.59	No	No	0	5	5
231	R:R:F303	R:R:T283	2.59	Yes	No	0	4	5
232	R:R:I197	R:R:R178	2.51	No	No	0	4	4
233	R:R:F309	R:R:M276	2.49	No	Yes	0	7	8
234	R:R:F216	R:R:L217	2.44	Yes	No	0	8	4
235	R:R:F263	R:R:L231	2.44	No	No	0	7	6
236	R:R:T101	R:R:W100	2.43	No	No	0	4	5
237	R:R:L302	R:R:W299	2.28	No	No	0	5	4
238	R:R:F263	R:R:F267	2.14	No	No	0	7	5
239	R:R:R183	R:R:R24	2.13	Yes	No	0	3	5
240	R:R:R68	R:R:R71	2.13	No	No	0	6	7
241	R:R:F176	R:R:W198	2	No	Yes	0	5	7
242	R:R:A73	R:R:G72	1.95	No	No	0	6	7
243	R:R:A154	R:R:G151	1.95	No	No	0	5	7
244	R:R:A167	R:R:G164	1.95	No	No	0	3	4
245	R:R:G203	R:R:T200	1.82	No	No	0	3	3
246	R:R:P279	R:R:V306	1.77	No	No	0	9	6
247	R:R:P199	R:R:T200	1.75	No	No	0	6	3
248	R:R:A315	R:R:S54	1.71	No	No	0	6	8
249	R:R:C60	R:R:V59	1.71	No	No	0	6	3
250	R:R:C111	R:R:V179	1.71	No	No	0	9	5
251	R:R:A315	R:R:V53	1.7	No	No	0	6	5
252	R:R:A312	R:R:I50	1.62	No	No	0	5	7
253	R:R:A103	R:R:I191	1.62	No	No	0	5	4
254	R:R:T44	R:R:V48	1.59	No	No	0	6	4
255	R:R:A308	R:R:L47	1.58	No	Yes	0	4	6
256	R:R:A131	R:R:L77	1.58	No	No	0	7	7
257	R:R:A167	R:R:L120	1.58	No	No	0	3	5
258	R:R:A246	R:R:L241	1.58	No	No	0	4	5
259	R:R:C83	R:R:N80	1.57	No	Yes	0	5	9
260	R:R:I233	R:R:V141	1.54	No	No	0	5	6
261	R:R:I205	R:R:V209	1.54	No	No	0	4	4
262	R:R:K229	R:R:S228	1.53	Yes	No	0	5	3
263	R:R:M137	R:R:V141	1.52	No	No	0	8	6
264	R:R:L37	R:R:V38	1.49	No	No	0	3	3
265	R:R:D259	R:R:V255	1.46	No	No	0	7	5
266	R:R:I275	R:R:M276	1.46	No	Yes	0	5	8
267	R:R:D259	R:R:T234	1.45	No	No	0	7	8
268	R:R:H251	R:R:S248	1.39	Yes	No	0	2	6
269	R:R:H35	R:R:V38	1.38	No	No	0	3	3
270	R:R:H142	R:R:V138	1.38	No	No	0	5	4
271	R:R:L158	R:R:L161	1.38	No	No	0	5	2
272	R:R:I191	R:R:Q182	1.37	No	No	0	4	2
273	R:R:I253	R:R:Q257	1.37	No	No	0	3	5
274	R:R:R254	R:R:S250	1.32	No	No	0	4	5
275	R:R:L79	R:R:R69	1.21	No	No	0	5	7
276	R:R:Q258	R:R:R254	1.17	No	No	0	6	4

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:?1	5.86	10	1	0
2	R:R:F25	6.365	6	0	5
3	R:R:F27	7.115	4	1	5
4	R:R:F28	7.078	5	1	8
5	R:R:K32	4.7475	4	5	3
6	R:R:L47	4.7175	4	0	6
7	R:R:N58	10.4275	4	3	9
8	R:R:N80	6.49	5	7	9
9	R:R:F82	5.185	6	3	9
10	R:R:F88	6.04	4	0	7
11	R:R:I89	6.0775	4	6	6
12	R:R:I92	6.48	5	6	7
13	R:R:W104	8.98	5	4	9
14	R:R:F115	6.27	4	1	5
15	R:R:M118	4.5025	4	0	7
16	R:R:T119	4.1025	4	1	5
17	R:R:V124	7.765	4	7	7
18	R:R:R136	5.265	4	2	9
19	R:R:F177	7.7075	4	1	5
20	R:R:R183	5.1175	4	0	3
21	R:R:W198	15.4875	4	0	7
22	R:R:W207	9.244	5	0	6
23	R:R:D208	7.4275	4	1	5
24	R:R:F211	5.648	5	1	5
25	R:R:N215	8.0075	4	0	6
26	R:R:F216	6.4575	4	0	8
27	R:R:Y227	5.20571	7	2	9
28	R:R:K229	5.625	4	0	5
29	R:R:Y247	6.6425	4	9	4
30	R:R:H251	4.9625	4	9	2
31	R:R:F273	4.844	5	2	9
32	R:R:M276	5.084	5	0	8
33	R:R:W277	10.205	4	2	9
34	R:R:F303	4.5775	4	1	4
35	R:R:F311	7.4675	4	0	7
36	R:R:Y321	4.87	5	2	9
37	R:R:N322	4.075	4	3	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:F27	28.6794	4.89	Yes	Yes	1	0	5
2	R:R:F25	R:R:F27	21.5362	7.5	Yes	Yes	0	5	5
3	R:R:F25	R:R:P26	30.9523	4.33	Yes	No	0	5	5
4	R:R:P26	R:R:R183	17.5638	4.32	No	Yes	0	5	3
5	L:L:?1	R:R:I287	20.3744	4.59	Yes	No	0	0	5
6	R:R:F25	R:R:I287	19.4612	5.02	Yes	No	0	5	5
7	R:R:R183	R:R:R24	12.9572	2.13	Yes	No	0	3	5
8	R:R:P26	R:R:S29	11.8056	5.34	No	No	0	5	9
9	L:L:?1	R:R:F88	33.6411	4.89	Yes	Yes	0	0	7
10	R:R:F311	R:R:F88	29.9376	9.65	Yes	Yes	0	7	7
11	L:L:?1	R:R:M118	31.3378	6.82	Yes	Yes	0	0	7
12	R:R:F311	R:R:M118	29.8463	3.73	Yes	Yes	0	7	7
13	R:R:F311	R:R:I92	63.5077	12.56	Yes	Yes	0	7	7
14	R:R:I92	R:R:L47	43.9856	4.28	Yes	Yes	0	7	6
15	R:R:F304	R:R:L47	36.0154	6.09	No	Yes	0	4	6
16	R:R:F304	R:R:R99	24.2301	27.79	No	No	0	4	4
17	R:R:K32	R:R:R99	20.9375	7.43	Yes	No	5	3	4
18	R:R:K32	R:R:L39	16.1585	2.82	Yes	No	0	3	4
19	R:R:D34	R:R:L39	14.4031	6.79	No	No	0	3	4
20	R:R:D34	R:R:H35	12.6376	3.78	No	No	0	3	3
21	R:R:H35	R:R:V38	10.862	1.38	No	No	0	3	3
22	R:R:E43	R:R:F304	10.5068	9.33	No	No	0	5	4
23	R:R:I89	R:R:I92	17.7515	5.89	Yes	Yes	6	6	7
24	L:L:?1	R:R:I280	96.6465	8.03	Yes	No	1	0	6
25	R:R:I280	R:R:T310	100	4.56	No	No	0	6	8
26	R:R:T310	R:R:W277	99.4064	3.64	No	Yes	0	8	9
27	R:R:F273	R:R:W277	88.098	5.01	Yes	Yes	2	9	9
28	R:R:F273	R:R:L129	82.1166	3.65	Yes	No	2	9	8
29	R:R:L129	R:R:Y321	62.1125	7.03	No	Yes	2	8	9
30	R:R:R136	R:R:Y321	27.3046	5.14	Yes	Yes	2	9	9
31	R:R:E135	R:R:R136	27.8525	3.49	No	Yes	0	8	9
32	R:R:C76	R:R:E135	26.4776	6.08	No	No	0	5	8
33	R:R:C76	R:R:V78	25.0926	3.42	No	No	0	5	8
34	R:R:F82	R:R:V78	23.6974	3.93	Yes	No	0	9	8
35	R:R:F82	R:R:N322	13.6472	4.83	Yes	Yes	3	9	7
36	R:R:L129	R:R:L81	19.1517	5.54	No	No	2	8	9
37	R:R:L81	R:R:T128	21.9877	4.42	No	No	0	9	8
38	R:R:N80	R:R:T128	20.5926	8.77	Yes	No	0	9	8
39	R:R:N80	R:R:V124	11.9679	4.43	Yes	Yes	7	9	7
40	R:R:C111	R:R:W104	11.2069	5.22	No	Yes	4	9	9
41	L:L:?1	R:R:F211	15.7476	4.89	Yes	Yes	1	0	5
42	R:R:F211	R:R:N215	10.4003	9.67	Yes	Yes	0	5	6
43	R:R:Y227	R:R:Y321	33.2961	3.97	Yes	Yes	2	9	9
44	R:R:S133	R:R:Y227	21.8406	5.09	No	Yes	2	8	9
45	R:R:S133	R:R:S226	20.5215	6.52	No	No	0	8	5
46	R:R:M137	R:R:S226	14.8394	9.2	No	No	0	8	5
47	R:R:L266	R:R:Y227	10.5423	4.69	No	Yes	0	8	9
48	L:L:?1	R:R:E204	15.7729	4.26	Yes	No	0	0	5
49	R:R:E204	R:R:W198	13.1247	31.62	No	Yes	0	5	7
50	R:R:F176	R:R:W198	13.8755	2	No	Yes	0	5	7
51	R:R:F176	R:R:P199	10.862	7.22	No	No	0	5	6
52	R:R:N313	R:R:W277	16.3462	18.08	No	Yes	0	9	9
53	R:R:M276	R:R:N313	13.4646	11.22	Yes	No	0	8	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?1	R:R:F27	4.89	1	Yes	Yes	0	5	0	1
L:L:?1	R:R:F88	4.89	1	Yes	Yes	0	7	0	1
L:L:?1	R:R:M118	6.82	1	Yes	Yes	0	7	0	1
L:L:?1	R:R:T119	4.74	1	Yes	Yes	0	5	0	1
L:L:?1	R:R:E204	4.26	1	Yes	No	0	5	0	1
L:L:?1	R:R:D208	10.9	1	Yes	Yes	0	5	0	1
L:L:?1	R:R:F211	4.89	1	Yes	Yes	0	5	0	1
L:L:?1	R:R:I280	8.03	1	Yes	No	0	6	0	1
L:L:?1	R:R:I284	4.59	1	Yes	No	0	5	0	1
L:L:?1	R:R:I287	4.59	1	Yes	No	0	5	0	1
R:R:F25	R:R:F27	7.5	0	Yes	Yes	5	5	2	1
R:R:F25	R:R:I287	5.02	0	Yes	No	5	5	2	1
R:R:F115	R:R:F27	8.57	1	Yes	Yes	5	5	2	1
R:R:F177	R:R:F27	7.5	1	Yes	Yes	5	5	2	1
R:R:F88	R:R:S121	6.61	0	Yes	No	7	8	1	2
R:R:F311	R:R:F88	9.65	0	Yes	Yes	7	7	2	1
R:R:F115	R:R:L114	3.65	1	Yes	No	5	6	2	2
R:R:L114	R:R:M118	4.24	0	No	Yes	6	7	2	1
R:R:F115	R:R:F177	7.5	1	Yes	Yes	5	5	2	2
R:R:F311	R:R:M118	3.73	0	Yes	Yes	7	7	2	1
R:R:L173	R:R:T119	4.42	0	No	Yes	5	5	2	1
R:R:F211	R:R:T119	3.89	1	Yes	Yes	5	5	1	1
R:R:F177	R:R:L173	3.65	1	Yes	No	5	5	2	2
R:R:L173	R:R:W207	7.97	0	No	Yes	5	6	2	2
R:R:E204	R:R:W198	31.62	0	No	Yes	5	7	1	2
R:R:W198	R:R:W207	11.25	0	Yes	Yes	7	6	2	2
R:R:E204	R:R:N291	9.2	0	No	No	5	2	1	2
R:R:D208	R:R:W207	7.82	1	Yes	Yes	5	6	1	2
R:R:F211	R:R:W207	7.02	1	Yes	Yes	5	6	1	2
R:R:D208	R:R:I284	4.2	1	Yes	No	5	5	1	1
R:R:D208	R:R:L288	6.79	1	Yes	No	5	4	1	2
R:R:F211	R:R:N215	9.67	1	Yes	Yes	5	6	1	2
R:R:I280	R:R:I284	4.42	1	No	No	6	5	1	1
R:R:I280	R:R:T310	4.56	1	No	No	6	8	1	2
R:R:A170	R:R:T119	3.36	0	No	Yes	7	5	2	1
R:R:A91	R:R:M118	3.22	0	No	Yes	6	7	2	1
R:R:F88	R:R:G122	3.01	0	Yes	No	7	7	1	2
R:R:A169	R:R:F211	2.77	0	No	Yes	5	5	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	8ID4_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.49
Number of Linked Nodes	256
Number of Links	276
Number of Hubs	37
Number of Links mediated by Hubs	138
Number of Communities	9
Number of Nodes involved in Communities	49
Number of Links involved in Communities	59

Path Summary
Number Of Nodes in MetaPath	54
Number Of Links MetaPath	53
Number of Shortest Paths	35393
Length Of Smallest Path	3
Average Path Length	12.9573
Length of Longest Path	32
Minimum Path Strength	1.245
Average Path Strength	6.15225
Maximum Path Strength	24.35
Minimum Path Correlation	0.7
Average Path Correlation	0.943205
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	5
Average % Of Corr. Nodes	63.0099
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	46.762
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• molecular transducer activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • protein binding • binding • arrestin family protein binding • fatty acid binding • organic acid binding • ion binding • anion binding • lipid binding • carboxylic acid binding • monocarboxylic acid binding • small molecule binding • taste receptor activity • positive regulation of cytosolic calcium ion concentration • biological regulation • regulation of biological quality • regulation of localization • nitrogen compound transport • regulation of hormone secretion • regulation of cellular process • regulation of peptide secretion • transport • signaling • negative regulation of signaling • negative regulation of biological process • negative regulation of transport • hormone secretion
Gene Ontology	Biological Process	• positive regulation of cytosolic calcium ion concentration • biological regulation • regulation of biological quality • regulation of localization • nitrogen compound transport • regulation of hormone secretion • regulation of cellular process • regulation of peptide secretion • transport • signaling • negative regulation of signaling • negative regulation of biological process • negative regulation of transport • hormone secretion • somatostatin secretion • negative regulation of cell communication • cell communication • negative regulation of peptide secretion • negative regulation of somatostatin secretion • peptide secretion • localization • secretion by cell • regulation of secretion by cell • negative regulation of secretion • amide transport • signal release • negative regulation of hormone secretion • negative regulation of cellular process • negative regulation of secretion by cell • regulation of peptide hormone secretion • regulation of biological process • regulation of signaling • negative regulation of peptide hormone secretion • secretion • regulation of transport • regulation of hormone levels • regulation of peptide transport • cell-cell signaling • export from cell • establishment of localization • regulation of secretion • peptide transport • regulation of somatostatin secretion • peptide hormone secretion • hormone transport • regulation of cell communication • cellular process • cellular response to stimulus • positive regulation of cell communication • positive regulation of signal transduction • response to stimulus • positive regulation of biological process • regulation of signal transduction • intracellular signal transduction • positive regulation of response to stimulus • positive regulation of ERK1 and ERK2 cascade • regulation of intracellular signal transduction • intracellular signaling cassette • signal transduction • positive regulation of cellular process • positive regulation of MAPK cascade • positive regulation of intracellular signal transduction • regulation of MAPK cascade • regulation of response to stimulus • MAPK cascade • ERK1 and ERK2 cascade • regulation of ERK1 and ERK2 cascade • positive regulation of signaling • negative regulation of programmed cell death • regulation of apoptotic process • regulation of programmed cell death • cell death • negative regulation of apoptotic process • apoptotic process • programmed cell death • regulation of defense response • regulation of response to external stimulus • negative regulation of inflammatory response • defense response • negative regulation of response to stimulus • response to external stimulus • regulation of inflammatory response • response to stress • negative regulation of response to external stimulus • regulation of response to stress • negative regulation of defense response • inflammatory response • hexose transmembrane transport • carbohydrate transport • transmembrane transport • regulation of transmembrane transport • D-glucose transmembrane transport • regulation of D-glucose transmembrane transport • monosaccharide transmembrane transport • carbohydrate transmembrane transport • multicellular organismal process • interleukin-1 production • regulation of interleukin-1 beta production • negative regulation of interleukin-1 beta production • negative regulation of interleukin-1 production • regulation of cytokine production • cytokine production • regulation of multicellular organismal process • negative regulation of macromolecule metabolic process • regulation of biosynthetic process • regulation of interleukin-1 production • negative regulation of metabolic process • negative regulation of cytokine production • regulation of macromolecule metabolic process • gene expression • macromolecule biosynthetic process • regulation of gene expression • negative regulation of gene expression • biosynthetic process • negative regulation of biosynthetic process • interleukin-1 beta production • negative regulation of macromolecule biosynthetic process • regulation of macromolecule biosynthetic process • metabolic process • macromolecule metabolic process • negative regulation of multicellular organismal process • regulation of metabolic process • adenylate cyclase-activating G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • ghrelin secretion • homeostatic process • adaptive thermogenesis • positive regulation of metabolic process • multicellular organismal-level homeostasis • regulation of cold-induced thermogenesis • cold-induced thermogenesis • temperature homeostasis • positive regulation of cold-induced thermogenesis • positive regulation of multicellular organismal process • developmental process • regulation of osteoblast differentiation • cellular developmental process • regulation of developmental process • regulation of cell differentiation • osteoblast differentiation • positive regulation of developmental process • positive regulation of osteoblast differentiation • ossification • positive regulation of cell differentiation • cell differentiation • phospholipase C-activating G protein-coupled receptor signaling pathway • fat cell differentiation • positive regulation of brown fat cell differentiation • positive regulation of fat cell differentiation • regulation of brown fat cell differentiation • brown fat cell differentiation • regulation of fat cell differentiation • glucagon secretion • positive regulation of secretion by cell • positive regulation of hormone secretion • positive regulation of secretion • regulation of glucagon secretion • positive regulation of peptide secretion • positive regulation of glucagon secretion • positive regulation of peptide hormone secretion • positive regulation of transport • white fat cell differentiation • membrane-bounded organelle • cell projection • cellular anatomical structure • organelle • cilium • plasma membrane bounded cell projection • cell periphery • plasma membrane • membrane • intracellular organelle • intracellular anatomical structure • intracellular membrane-bounded organelle • intracellular vesicle • cytoplasmic vesicle
Gene Ontology	Cellular Component	• membrane-bounded organelle • cell projection • cellular anatomical structure • organelle • cilium • plasma membrane bounded cell projection • cell periphery • plasma membrane • membrane • intracellular organelle • intracellular anatomical structure • intracellular membrane-bounded organelle • intracellular vesicle • cytoplasmic vesicle • cytoplasm • vesicle • endocytic vesicle • ciliary membrane • bounding membrane of organelle • plasma membrane region • organelle membrane • cell projection membrane • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • lysosomal membrane • lysosome • endosome membrane • endosome • endomembrane system • cytoplasmic vesicle membrane • vesicle membrane • intracellular membraneless organelle • ciliary basal body • microtubule organizing center • cytoskeleton • membraneless organelle • microtubule cytoskeleton • D2 dopamine receptor binding • protein binding • binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • phosphorus-oxygen lyase activity • enzyme regulator activity • cyclase regulator activity • molecular function regulator activity • cyclase activity • adenylate cyclase regulator activity • lyase activity • catalytic activity • adenylate cyclase activity • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • cation binding • magnesium ion binding • metal ion binding • GDP binding • G protein-coupled serotonin receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • cell communication • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • response to hormone • response to chemical • response to endogenous stimulus • response to peptide hormone • response to oxygen-containing compound • response to nitrogen compound • cell division • leukocyte migration • immune system process • mononuclear cell migration • lymphocyte migration • cell migration • T cell migration • cell motility • regulation of steroid biosynthetic process • regulation of cholesterol biosynthetic process • regulation of cholesterol metabolic process • steroid metabolic process • regulation of lipid metabolic process • sterol metabolic process • positive regulation of biological process • cholesterol metabolic process • lipid biosynthetic process • alcohol metabolic process • regulation of primary metabolic process • positive regulation of metabolic process • regulation of small molecule metabolic process • positive regulation of biosynthetic process • positive regulation of lipid metabolic process • small molecule metabolic process • steroid biosynthetic process • positive regulation of cellular process • regulation of biosynthetic process • secondary alcohol biosynthetic process • regulation of alcohol biosynthetic process • small molecule biosynthetic process • regulation of steroid metabolic process • cholesterol biosynthetic process • positive regulation of cholesterol biosynthetic process • primary metabolic process • secondary alcohol metabolic process • positive regulation of steroid biosynthetic process • biosynthetic process • sterol biosynthetic process • positive regulation of lipid biosynthetic process • regulation of sterol biosynthetic process • alcohol biosynthetic process • positive regulation of cholesterol metabolic process • positive regulation of steroid metabolic process • metabolic process • regulation of lipid biosynthetic process • positive regulation of small molecule metabolic process • regulation of metabolic process • positive regulation of alcohol biosynthetic process • positive regulation of sterol biosynthetic process • lipid metabolic process • regulation of cytoskeleton organization • regulation of cellular component organization • microtubule cytoskeleton organization • regulation of mitotic spindle organization • mitotic cell cycle • cellular component organization • cell cycle • cellular component organization or biogenesis • regulation of cell cycle • microtubule cytoskeleton organization involved in mitosis • spindle organization • cell cycle process • regulation of cell cycle process • regulation of microtubule-based process • regulation of spindle organization • regulation of organelle organization • mitotic spindle organization • organelle organization • mitotic cell cycle process • microtubule-based process • cytoskeleton organization • regulation of microtubule cytoskeleton organization • protein localization • positive regulation of protein localization to cell periphery • regulation of localization • protein localization to cell periphery • cellular localization • regulation of protein localization • positive regulation of protein localization to cell cortex • regulation of protein localization to cell periphery • localization • regulation of cellular localization • regulation of protein localization to cell cortex • cellular macromolecule localization • macromolecule localization • positive regulation of protein localization • protein localization to cell cortex • response to ketone • response to prostaglandin • response to lipid • response to alcohol • response to prostaglandin E • cellular response to forskolin • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to alcohol • response to forskolin • cellular response to lipid • cellular response to ketone • midbody • nucleus • membrane-enclosed lumen • nucleolus • intracellular organelle lumen • organelle lumen • nuclear lumen • cell cortex • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular region • extracellular space • extracellular membrane-bounded organelle • centrosome • centriolar satellite • cytosol • nucleoplasm • Golgi apparatus • enzyme binding • GTPase binding • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • photoreceptor cell cilium • synapse • cell junction • G-protein beta-subunit binding • fibroblast proliferation
SCOP2	Domain Identifier	• Ras-like P-loop GTPases • Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Ras-like P-loop GTPases • Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	EIC
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	EIC
Name	Linoleic acid
Synonyms	9Z,12Z-octadecadienoic acid
Identifier
Formula	C18 H32 O2
Molecular Weight	280.445
SMILES
PubChem	5280450
Formal Charge	0
Total Atoms	52
Total Chiral Atoms	0
Total Bonds	51
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q5NUL3
Sequence	>8ID4_nogp_Chain_R T R F P F F S D V K G D H R L V L A A V E T T V L V L I F A V S L L G N V C A L V L V A R R R R R G A C L V L N L F C A D L L F I S A I P L V L A V R W T E A W G P V A C H L L F Y V M T L S G S V T I L T L A A V S L E R M V C I V H L G R R A R A V L L A L I W G Y S A V A A L P L C V F F R V V P Q R I S I C T L I W P T I P G E I S W D V S F V T L N F L V P G L V I V I S Y S K I L Q I T K A S R K R L T V S L A Y S E S H Q I R V S Q Q D F R L F R T L F L L M V S F F I M W S P I I I T I L L I L I Q N F K Q D L V I W P S L F F W V V A F T F A N S A L N P I L Y N M T L Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8T3Q	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	Docosa-4,7,10,13,16,19-Hexaenoic acid	-	chim(NtGi2L-Gs-CtGq)/β1/γ2	3.14	2024-01-24	10.1126/sciadv.adj2384
	8T3Q (No Gprot)	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	Docosa-4,7,10,13,16,19-Hexaenoic acid	-		3.14	2024-01-24	10.1126/sciadv.adj2384
	8T3O	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	TUG-891	2Y5	chim(NtGi2L-Gs-CtGq)/β1/γ2	3.06	2024-01-17	10.1126/sciadv.adj2384
	8T3O (No Gprot)	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	TUG-891	2Y5		3.06	2024-01-17	10.1126/sciadv.adj2384
	8H4L	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	Doconexent	-	chim(NtGi1-Gs-CtGq)/β1/γ2	3.07	2023-06-21	10.1038/s41422-023-00835-x
	8H4L (No Gprot)	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	Doconexent	-		3.07	2023-06-21	10.1038/s41422-023-00835-x
	8H4K	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	GW9508	-	chim(NtGi1-Gs-CtGq)/β1/γ2	3.1	2023-06-21	10.1038/s41422-023-00835-x
	8H4K (No Gprot)	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	GW9508	-		3.1	2023-06-21	10.1038/s41422-023-00835-x
	8H4I	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	Doconexent	-	chim(NtGi1-Gs)/β1/γ2	3.06	2023-06-21	10.1038/s41422-023-00835-x
	8H4I (No Gprot)	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	Doconexent	-		3.06	2023-06-21	10.1038/s41422-023-00835-x
	8IYS	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	TUG-891	GDP	chim(NtGi1L-Gq)/β1/γ2	2.95	2023-06-21	10.1038/s41422-023-00835-x
	8IYS (No Gprot)	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	TUG-891	GDP		2.95	2023-06-21	10.1038/s41422-023-00835-x
	8ID9	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	Eicosapentaenoic acid	-	Gi1/β1/γ2	3	2023-03-15	10.1126/science.add6220
	8ID9 (No Gprot)	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	Eicosapentaenoic acid	-		3	2023-03-15	10.1126/science.add6220
	8ID8	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	TUG-891	-	Gi1/β1/γ2	3	2023-03-15	10.1126/science.add6220
	8ID8 (No Gprot)	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	TUG-891	-		3	2023-03-15	10.1126/science.add6220
	8ID6	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	Oleic acid	-	Gi1/β1/γ2	2.8	2023-03-15	10.1126/science.add6220
	8ID6 (No Gprot)	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	Oleic acid	-		2.8	2023-03-15	10.1126/science.add6220
	8ID4	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	Linoleic acid	-	Gi1/β1/γ2	3.1	2023-03-15	10.1126/science.add6220
	8ID4 (No Gprot)	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	Linoleic acid	-		3.1	2023-03-15	10.1126/science.add6220
	8ID3	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	9-Hydroxystearic acid	-	Gi1/β1/γ2	3.1	2023-03-15	10.1126/science.add6220
	8ID3 (No Gprot)	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	9-Hydroxystearic acid	-		3.1	2023-03-15	10.1126/science.add6220
	8G59	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	TUG-891	-	chim(Gi1-CtGq)/β1/γ2	2.64	2023-03-08	10.1126/science.add6220
	8G59 (No Gprot)	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	TUG-891	-		2.64	2023-03-08	10.1126/science.add6220

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