Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index Hub Avg Int. Strength Num Of Links Community ConSurf
1L:L:K23 6.812510
2L:L:F26 6.54410
3R:R:L31 2.475403
4R:R:I37 5.27466
5R:R:I40 5.9175407
6R:R:L55 6.6575448
7R:R:Y67 7.49833627
8R:R:F76 3.87407
9R:R:F81 6.015405
10R:R:Q82 5.19465
11R:R:M109 6.305404
12R:R:Y113 8.482518
13R:R:R141 7.06167628
14R:R:K166 5.1525433
15R:R:F167 6.935434
16R:R:F170 6.328513
17R:R:L171 5.306501
18R:R:F183 5.666534
19R:R:D184 6.665413
20R:R:F195 5.8525406
21R:R:I225 4.3425407
22R:R:F232 8.88409
23R:R:F239 7.962516
24R:R:Q242 7.8675411
25R:R:W243 6.22143714
26R:R:H261 6.008512
27R:R:N275 6.805459
28R:R:Y279 8.072559
29R:R:F280 7.262548
   

Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index Node1 Node2 Recurrence Int. Strength Hub1? Hub2? Community ConSurf1 ConSurf2
1L:L:K23 R:R:W243 10.34996.96YesYes104
2L:L:F26 R:R:M109 13.16157.46YesYes004
3R:R:F81 R:R:M109 56.4567.46YesYes054
4R:R:C80 R:R:F81 48.24022.79NoYes045
5R:R:C80 R:R:L45 47.14511.59NoNo047
6R:R:I83 R:R:L45 41.6344.28NoNo067
7R:R:I83 R:R:L42 39.31655.71NoNo065
8R:R:L38 R:R:L42 38.13992.77NoNo055
9R:R:C86 R:R:L38 18.56577.94NoNo055
10R:R:C86 R:R:V34 17.28723.42NoNo054
11R:R:V34 R:R:Y89 16.008810.09NoNo042
12R:R:L31 R:R:Y89 14.72012.34YesNo032
13R:R:F93 R:R:L31 21.69823.65NoYes013
14R:R:L38 R:R:L87 18.42311.38NoNo054
15R:R:L87 R:R:L90 17.29231.38NoNo044
16R:R:F35 R:R:L90 15.99863.65NoNo044
17R:R:F35 R:R:L31 14.72522.44NoYes043
18R:R:M109 R:R:Q82 16.84924.08YesYes045
19R:R:I37 R:R:Q82 12.83044.12YesYes665
20R:R:F239 R:R:W243 24.33668.02YesYes164
21R:R:F239 R:R:Y113 34.126217.54YesYes168
22R:R:L117 R:R:Y113 93.26648.21NoYes088
23R:R:F232 R:R:L117 94.05086.09YesNo098
24R:R:F232 R:R:L120 51.26578.53YesNo099
25R:R:L120 R:R:Y279 50.236817.58NoYes099
26R:R:N275 R:R:Y279 22.09558.14YesYes599
27R:R:D75 R:R:N275 11.18525.39NoYes099
28R:R:V123 R:R:Y279 26.94953.79NoYes599
29R:R:F64 R:R:V123 24.51485.24NoNo579
30R:R:F64 R:R:V68 23.51653.93NoNo078
31R:R:F280 R:R:V68 22.31453.93YesNo088
32R:R:F280 R:R:L55 17.047813.4YesYes488
33R:R:L55 R:R:L69 10.01385.54YesNo487
34R:R:F232 R:R:L198 10013.4YesNo098
35R:R:L198 R:R:S124 98.0394.5NoNo089
36R:R:S124 R:R:S202 95.00844.89NoNo098
37R:R:I225 R:R:S202 93.82163.1YesNo078
38R:R:I225 R:R:L205 85.38684.28YesNo078
39R:R:L205 R:R:V131 84.80114.47NoNo088
40R:R:S130 R:R:V131 84.31213.23NoNo088
41R:R:S130 R:R:Y137 83.71117.63NoNo087
42R:R:E126 R:R:Y137 37.01425.61NoNo297
43R:R:E126 R:R:Y67 36.163613.47NoYes297
44R:R:R141 R:R:Y137 46.075518.52YesNo287
45R:R:R141 R:R:Y67 37.76295.14YesYes287
46R:R:M119 R:R:Y67 64.17263.59NoYes267
47R:R:M119 R:R:S70 60.03679.2NoNo269
48R:R:S70 R:R:W154 58.16747.41NoNo099
49R:R:F93 R:R:F94 19.03436.43NoNo013
50R:R:C95 R:R:F94 16.34491.4NoNo043
51R:R:C95 R:R:I97 13.64543.27NoNo045
52R:R:A115 R:R:W154 52.070511.67NoNo079
53R:R:A115 R:R:S157 50.01783.42NoNo078
54R:R:C111 R:R:S157 45.88195.16NoNo058
55R:R:C111 R:R:S161 41.70533.44NoNo057
56R:R:S161 R:R:T107 37.48794.8NoNo074
57R:R:L171 R:R:T107 35.36395.9YesNo014
58R:R:L198 R:R:S121 11.16494.5NoNo087
59R:R:S124 R:R:S201 12.44843.26NoNo098
60R:R:K166 R:R:L171 26.76627.05YesYes031
61R:R:F167 R:R:K166 20.21092.48YesYes343
62R:R:F195 R:R:F232 15.23467.5YesYes069
63R:R:F195 R:R:L237 11.20056.09YesNo066
64R:R:I225 R:R:L221 20.25164.28YesNo078
65R:R:I209 R:R:L221 18.95285.71NoNo068
66R:R:I209 R:R:S213 12.45869.29NoNo067
67R:R:L216 R:R:S213 11.10384.5NoNo047
68R:R:N271 R:R:N275 11.7715.45NoYes099
69R:R:F78 R:R:M109 59.12496.22NoYes064
70R:R:F78 R:R:Y113 57.68357.22NoYes168
71R:R:F239 R:R:Q242 10.82874.68YesYes161
Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Links and nodes colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
L:L:K23 R:R:F170 9.93 1 Yes Yes 0 3 0 1
L:L:K23 R:R:D184 8.3 1 Yes Yes 0 3 0 1
L:L:K23 R:R:W243 6.96 1 Yes Yes 0 4 0 1
L:L:K23 R:R:L247 4.23 1 Yes No 0 3 0 1
L:L:K23 R:R:W248 4.64 1 Yes No 0 3 0 1
L:L:N24 R:R:L247 4.12 0 No No 0 3 0 1
L:L:F26 R:R:T106 3.89 1 Yes No 0 5 0 1
L:L:F26 R:R:M109 7.46 1 Yes Yes 0 4 0 1
L:L:F26 R:R:W243 8.02 1 Yes Yes 0 4 0 1
L:L:F26 R:R:H261 6.79 1 Yes Yes 0 2 0 1
R:R:F78 R:R:M109 6.22 1 No Yes 6 4 2 1
R:R:F239 R:R:F78 4.29 1 Yes No 6 6 2 2
R:R:F81 R:R:M109 7.46 0 Yes Yes 5 4 2 1
R:R:M109 R:R:Q82 4.08 0 Yes Yes 4 5 1 2
R:R:S103 R:R:T106 3.2 1 No No 5 5 2 1
R:R:F170 R:R:S103 3.96 1 Yes No 3 5 1 2
R:R:F170 R:R:T106 9.08 1 Yes No 3 5 1 1
R:R:E164 R:R:F170 4.66 0 No Yes 4 3 2 1
R:R:F170 R:R:W243 4.01 1 Yes Yes 3 4 1 1
R:R:Q181 R:R:W248 13.14 0 No No 3 3 2 1
R:R:D184 R:R:T187 4.34 1 Yes No 3 4 1 2
R:R:D184 R:R:F244 9.55 1 Yes No 3 5 1 2
R:R:D184 R:R:W248 4.47 1 Yes No 3 3 1 1
R:R:F244 R:R:T187 9.08 1 No No 5 4 2 2
R:R:F239 R:R:Q242 4.68 1 Yes Yes 6 1 2 2
R:R:F239 R:R:W243 8.02 1 Yes Yes 6 4 2 1
R:R:Q242 R:R:W243 3.29 1 Yes Yes 1 4 2 1
R:R:H261 R:R:Q242 14.84 1 Yes Yes 2 1 1 2
R:R:F244 R:R:W243 9.02 1 No Yes 5 4 2 1
R:R:H261 R:R:W243 4.23 1 Yes Yes 2 4 1 1
R:R:H261 R:R:P262 3.05 1 Yes No 2 1 1 2
L:L:F25 R:R:N100 2.42 0 No No 0 1 0 1
R:R:F257 R:R:H261 1.13 0 No Yes 3 2 2 1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB 7VDL_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.
Net Summary
Imin 3.1
Number of Linked Nodes 242
Number of Links 264
Number of Hubs 29
Number of Links mediated by Hubs 109
Number of Communities 9
Number of Nodes involved in Communities 54
Number of Links involved in Communities 70
Path Summary
Number Of Nodes in MetaPath 72
Number Of Links MetaPath 71
Number of Shortest Paths 37108
Length Of Smallest Path 3
Average Path Length 17.9007
Length of Longest Path 47
Minimum Path Strength 1.36
Average Path Strength 6.24893
Maximum Path Strength 13.73
Minimum Path Correlation 0.7
Average Path Correlation 0.924039
Maximum Path Correlation 0.99
Minimum % Of Corr. Nodes 2.63158
Average % Of Corr. Nodes 41.658
Maximum % Of Corr. Nodes 100
Minimum Path Hubs % 0
Average Path Hubs % 31.5949
Maximum Path Hubs % 100
AnnotationTypeLinks
Gene OntologyMolecular Function• D2 dopamine receptor binding   • protein binding   • binding   • signaling receptor binding   • G protein-coupled receptor binding   • dopamine receptor binding   • phosphorus-oxygen lyase activity   • enzyme regulator activity   • cyclase regulator activity   • molecular function regulator activity   • cyclase activity   • adenylate cyclase regulator activity   • lyase activity   • catalytic activity   • adenylate cyclase activity   • guanyl nucleotide binding   • GTP binding   • nucleotide binding   • guanyl ribonucleotide binding   • purine ribonucleotide binding   • purine ribonucleoside triphosphate binding   • nucleoside phosphate binding   • ion binding   • purine nucleotide binding   • anion binding   • heterocyclic compound binding   • carbohydrate derivative binding   • ribonucleotide binding   • small molecule binding   • cation binding   • magnesium ion binding   • metal ion binding   • GDP binding   • G protein-coupled serotonin receptor binding   • protein-containing complex binding   • G-protein beta/gamma-subunit complex binding   • pyrophosphatase activity   • GTPase activity   • G protein activity   • ribonucleoside triphosphate phosphatase activity   • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides   • hydrolase activity   • hydrolase activity, acting on acid anhydrides   • cellular response to stimulus   • regulation of biological process   • regulation of cellular process   • response to stimulus   • signaling   • biological regulation   • adenylate cyclase-inhibiting serotonin receptor signaling pathway   • G protein-coupled serotonin receptor signaling pathway   • cell communication   • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway   • adenylate cyclase-modulating G protein-coupled receptor signaling pathway   • G protein-coupled receptor signaling pathway   • cellular process   • signal transduction
Gene OntologyBiological Process• cellular response to stimulus   • regulation of biological process   • regulation of cellular process   • response to stimulus   • signaling   • biological regulation   • adenylate cyclase-inhibiting serotonin receptor signaling pathway   • G protein-coupled serotonin receptor signaling pathway   • cell communication   • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway   • adenylate cyclase-modulating G protein-coupled receptor signaling pathway   • G protein-coupled receptor signaling pathway   • cellular process   • signal transduction   • response to hormone   • response to chemical   • response to endogenous stimulus   • response to peptide hormone   • response to oxygen-containing compound   • response to nitrogen compound   • cell division   • leukocyte migration   • immune system process   • mononuclear cell migration   • lymphocyte migration   • cell migration   • T cell migration   • cell motility   • regulation of steroid biosynthetic process   • regulation of cholesterol biosynthetic process   • regulation of cholesterol metabolic process   • steroid metabolic process   • regulation of lipid metabolic process   • sterol metabolic process   • positive regulation of biological process   • cholesterol metabolic process   • lipid biosynthetic process   • alcohol metabolic process   • regulation of primary metabolic process   • positive regulation of metabolic process   • regulation of small molecule metabolic process   • positive regulation of biosynthetic process   • positive regulation of lipid metabolic process   • small molecule metabolic process   • steroid biosynthetic process   • positive regulation of cellular process   • regulation of biosynthetic process   • secondary alcohol biosynthetic process   • regulation of alcohol biosynthetic process   • small molecule biosynthetic process   • regulation of steroid metabolic process   • cholesterol biosynthetic process   • positive regulation of cholesterol biosynthetic process   • primary metabolic process   • secondary alcohol metabolic process   • positive regulation of steroid biosynthetic process   • biosynthetic process   • sterol biosynthetic process   • positive regulation of lipid biosynthetic process   • regulation of sterol biosynthetic process   • alcohol biosynthetic process   • positive regulation of cholesterol metabolic process   • positive regulation of steroid metabolic process   • metabolic process   • regulation of lipid biosynthetic process   • positive regulation of small molecule metabolic process   • regulation of metabolic process   • positive regulation of alcohol biosynthetic process   • positive regulation of sterol biosynthetic process   • lipid metabolic process   • regulation of cytoskeleton organization   • regulation of cellular component organization   • microtubule cytoskeleton organization   • regulation of mitotic spindle organization   • mitotic cell cycle   • cellular component organization   • cell cycle   • cellular component organization or biogenesis   • regulation of cell cycle   • microtubule cytoskeleton organization involved in mitosis   • spindle organization   • cell cycle process   • regulation of cell cycle process   • regulation of microtubule-based process   • regulation of spindle organization   • regulation of organelle organization   • mitotic spindle organization   • organelle organization   • mitotic cell cycle process   • microtubule-based process   • cytoskeleton organization   • regulation of microtubule cytoskeleton organization   • protein localization   • positive regulation of protein localization to cell periphery   • regulation of localization   • protein localization to cell periphery   • cellular localization   • regulation of protein localization   • positive regulation of protein localization to cell cortex   • regulation of protein localization to cell periphery   • localization   • regulation of cellular localization   • regulation of protein localization to cell cortex   • cellular macromolecule localization   • macromolecule localization   • positive regulation of protein localization   • protein localization to cell cortex   • response to ketone   • response to prostaglandin   • response to lipid   • response to alcohol   • response to prostaglandin E   • cellular response to forskolin   • cellular response to oxygen-containing compound   • cellular response to chemical stimulus   • cellular response to alcohol   • response to forskolin   • cellular response to lipid   • cellular response to ketone   • midbody   • cellular anatomical structure   • membrane-bounded organelle   • intracellular anatomical structure   • nucleus   • membrane-enclosed lumen   • intracellular membraneless organelle   • intracellular membrane-bounded organelle   • nucleolus   • intracellular organelle lumen   • intracellular organelle   • organelle lumen   • organelle   • membraneless organelle
Gene OntologyCellular Component• midbody   • cellular anatomical structure   • membrane-bounded organelle   • intracellular anatomical structure   • nucleus   • membrane-enclosed lumen   • intracellular membraneless organelle   • intracellular membrane-bounded organelle   • nucleolus   • intracellular organelle lumen   • intracellular organelle   • organelle lumen   • organelle   • membraneless organelle   • nuclear lumen   • cell periphery   • cell cortex   • cytoplasm   • protein-containing complex   • extrinsic component of plasma membrane   • catalytic complex   • plasma membrane protein complex   • cytoplasmic side of membrane   • membrane   • plasma membrane   • membrane protein complex   • heterotrimeric G-protein complex   • side of membrane   • cytoplasmic side of plasma membrane   • GTPase complex   • extrinsic component of membrane   • extrinsic component of cytoplasmic side of plasma membrane   • extracellular exosome   • extracellular vesicle   • extracellular organelle   • extracellular region   • extracellular space   • vesicle   • extracellular membrane-bounded organelle   • centrosome   • microtubule organizing center   • cytoskeleton   • microtubule cytoskeleton   • centriolar satellite   • cytosol   • nucleoplasm   • vacuolar membrane   • lytic vacuole   • vacuole   • lytic vacuole membrane   • bounding membrane of organelle   • lysosomal membrane   • organelle membrane   • lysosome   • Golgi apparatus   • endomembrane system   • cilium   • plasma membrane bounded cell projection   • ciliary basal body   • cell projection   • protein binding   • binding   • enzyme binding   • GTPase binding   • protein-containing complex binding   • pyrophosphatase activity   • GTPase activity   • ribonucleoside triphosphate phosphatase activity   • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides   • hydrolase activity   • hydrolase activity, acting on acid anhydrides   • catalytic activity   • signaling receptor complex adaptor activity   • protein-macromolecule adaptor activity   • molecular adaptor activity   • signaling adaptor activity   • multicellular organismal process   • system process   • sensory perception of chemical stimulus   • sensory perception   • nervous system process   • sensory perception of taste   • developmental process   • sensory organ development   • eye development   • animal organ development   • retina development in camera-type eye   • visual system development   • multicellular organism development   • camera-type eye development   • anatomical structure development   • sensory system development   • system development   • cell population proliferation   • cellular process   • cellular response to stimulus   • regulation of biological process   • regulation of cellular process   • response to stimulus   • signaling   • biological regulation   • signal transduction   • cell communication   • response to ketone   • response to prostaglandin   • response to lipid   • response to endogenous stimulus   • response to alcohol   • cellular response to prostaglandin stimulus   • response to oxygen-containing compound   • cellular response to oxygen-containing compound   • cellular response to endogenous stimulus   • cellular response to prostaglandin E stimulus   • cellular response to chemical stimulus   • cellular response to alcohol   • response to hormone   • response to chemical   • cellular response to lipid   • response to prostaglandin E   • cellular response to ketone   • cellular response to hormone stimulus   • small GTPase-mediated signal transduction   • Ras protein signal transduction   • intracellular signal transduction   • intracellular signaling cassette   • phospholipase C-activating G protein-coupled receptor signaling pathway   • G protein-coupled receptor signaling pathway   • cellular response to nitrogen compound   • response to dopamine   • cellular response to dopamine   • response to monoamine   • response to catecholamine   • adenylate cyclase-activating dopamine receptor signaling pathway   • cellular response to catecholamine stimulus   • G protein-coupled dopamine receptor signaling pathway   • response to nitrogen compound   • adenylate cyclase-activating G protein-coupled receptor signaling pathway   • cellular response to monoamine stimulus   • adenylate cyclase-modulating G protein-coupled receptor signaling pathway   • synaptic signaling   • cellular response to acetylcholine   • cell-cell signaling   • acetylcholine receptor signaling pathway   • postsynaptic signal transduction   • G protein-coupled acetylcholine receptor signaling pathway   • response to acetylcholine   • non-motile cilium   • 9+0 non-motile cilium   • neuron projection   • photoreceptor disc membrane   • photoreceptor outer segment   • photoreceptor cell cilium   • synapse   • cell junction   • G-protein beta-subunit binding   • fibroblast proliferation   • neuropeptide binding   • peptide binding   • molecular transducer activity   • G protein-coupled receptor activity   • transmembrane signaling receptor activity   • signaling receptor activity   • mast cell secretagogue receptor activity   • sleep   • regulation of cytokinesis   • positive regulation of cell division   • regulation of cell cycle process   • positive regulation of biological process   • cytokinesis   • positive regulation of cell cycle   • regulation of cell division   • positive regulation of cytokinesis   • positive regulation of cell cycle process   • cell division   • cell cycle   • regulation of cell cycle   • positive regulation of cellular process   • cell cycle process   • establishment of organelle localization   • regulated exocytosis   • cellular localization   • transport   • cell activation involved in immune response   • leukocyte degranulation   • myeloid leukocyte activation   • myeloid leukocyte mediated immunity   • vesicle-mediated transport   • leukocyte activation   • localization   • secretion by cell   • organelle localization   • leukocyte activation involved in immune response   • establishment of localization in cell   • mast cell activation   • leukocyte mediated immunity   • mast cell mediated immunity   • immune response   • secretion   • cell activation   • vacuolar localization   • export from cell   • mast cell degranulation   • establishment of localization   • myeloid cell activation involved in immune response   • immune effector process   • mast cell activation involved in immune response   • exocytosis   • immune system process   • lysosome localization   • sensory perception of pain   • molecular function activator activity   • signaling receptor binding   • neuropeptide activity   • signaling receptor activator activity   • hormone activity   • molecular function regulator activity   • neuropeptide hormone activity   • signaling receptor regulator activity   • receptor ligand activity   • G protein-coupled receptor binding   • regulation of cell motility   • regulation of locomotion   • regulation of cell migration   • cell migration   • cell motility   • locomotion   • trans-synaptic signaling   • anterograde trans-synaptic signaling   • chemical synaptic transmission   • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
SCOP2Domain Identifier• Ras-like P-loop GTPases   • Transducin (heterotrimeric G protein), gamma chain
SCOP2Family Identifier• Ras-like P-loop GTPases   • Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations-• Orientations of Proteins in Membranes database (OPM)   • Protein Data Bank of Transmembrane Proteins (PDBTM)   • MemProtMD


Details about the values in these tables can be found in the corresponding documentation page .
PDBsumOpen PDBsum Page
ChainR
ProteinReceptor
UniProtQ96LB1
Sequence
>7VDL_nogp_Chain_R
TLIPVFLIL FIALVGLVG NGFVLWLLG FRMRRNAFS VYVLSLAGA 
DFLFLCFQI INCLVYLSN FFCSISINF PSFFTTVMT CAYLAGLSM 
LSTVSTERC LSVLWPIWY RCRRPRHLS AVVCVLLWA LSLLLSILE 
GKFCGFLFS DGDSGWCQT FDFITAAWL IFLFMVLCG SSLALLVRI 
LCGSRGLPL TRLYLTILL TVLVFLLCG LPFGIQWFL ILWIWKDSD 
VLFCHIHPV SVVLSSLNS SANPIIYFF VGSF


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  




This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
7VV6AOrphanOrphanMRGPRX2Homo sapiensC48/80--3.32021-12-0110.1038/s41586-021-04077-y
7VV4AOrphanOrphanMRGPRX2Homo sapiensCortistatin-14--2.972021-12-0110.1038/s41586-021-04077-y
7VV0AOrphanOrphanMRGPRX2Homo sapiensPAMP-12--3.52021-12-0110.1038/s41586-021-04077-y
7VV5AOrphanOrphanMRGPRX2Homo sapiensC48/80-Gi1/β1/γ22.762021-12-0110.1038/s41586-021-04077-y
7VV5 (No Gprot) AOrphanOrphanMRGPRX2Homo sapiensC48/80-2.762021-12-0110.1038/s41586-021-04077-y
7VV3AOrphanOrphanMRGPRX2Homo sapiens--Gi1/β1/γ22.972021-12-0110.1038/s41586-021-04077-y
7VV3 (No Gprot) AOrphanOrphanMRGPRX2Homo sapiens--2.972021-12-0110.1038/s41586-021-04077-y
7VUZAOrphanOrphanMRGPRX2Homo sapiens--Gi1/β1/γ22.892021-12-0110.1038/s41586-021-04077-y
7VUZ (No Gprot) AOrphanOrphanMRGPRX2Homo sapiens--2.892021-12-0110.1038/s41586-021-04077-y
7VUYAOrphanOrphanMRGPRX2Homo sapiens--Gi1/β1/γ22.842021-12-0110.1038/s41586-021-04077-y
7VUY (No Gprot) AOrphanOrphanMRGPRX2Homo sapiens--2.842021-12-0110.1038/s41586-021-04077-y
7VDMAOrphanOrphanMRGPRX2Homo sapiensSubstance-P-Gi1/β1/γ22.982021-12-0110.1038/s41586-021-04077-y
7VDM (No Gprot) AOrphanOrphanMRGPRX2Homo sapiensSubstance-P-2.982021-12-0110.1038/s41586-021-04077-y
7VDLAOrphanOrphanMRGPRX2Homo sapiensCortistatin-14-Gi1/β1/γ23.222021-12-0110.1038/s41586-021-04077-y
7VDL (No Gprot) AOrphanOrphanMRGPRX2Homo sapiensCortistatin-14-3.222021-12-0110.1038/s41586-021-04077-y
7VDHAOrphanOrphanMRGPRX2Homo sapiensC48/80-Gi1/β1/γ22.92021-12-0110.1038/s41586-021-04077-y
7VDH (No Gprot) AOrphanOrphanMRGPRX2Homo sapiensC48/80-2.92021-12-0110.1038/s41586-021-04077-y
7S8NAOrphanOrphanMRGPRX2Homo sapiensR-Zinc-3573-chim(NtGi2L-Gs-CtGq)/β1/γ22.92021-11-1710.1038/s41586-021-04126-6
7S8N (No Gprot) AOrphanOrphanMRGPRX2Homo sapiensR-Zinc-3573-2.92021-11-1710.1038/s41586-021-04126-6
7S8LAOrphanOrphanMRGPRX2Homo sapiensCortistatin-14-chim(NtGi2L-Gs-CtGq)/β1/γ22.452021-11-1710.1038/s41586-021-04126-6
7S8L (No Gprot) AOrphanOrphanMRGPRX2Homo sapiensCortistatin-14-2.452021-11-1710.1038/s41586-021-04126-6
7S8OAOrphanOrphanMRGPRX2Homo sapiensR-Zinc-3573-Gi1/β1/γ22.582021-11-1710.1038/s41586-021-04126-6
7S8O (No Gprot) AOrphanOrphanMRGPRX2Homo sapiensR-Zinc-3573-2.582021-11-1710.1038/s41586-021-04126-6
7S8MAOrphanOrphanMRGPRX2Homo sapiensCortistatin-14-Gi1/β1/γ22.542021-11-1710.1038/s41586-021-04126-6
7S8M (No Gprot) AOrphanOrphanMRGPRX2Homo sapiensCortistatin-14-2.542021-11-1710.1038/s41586-021-04126-6




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