psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:L12	R:R:T14	5.9	No	No	0	3	5
2	R:R:R15	R:R:T14	3.88	No	No	0	3	5
3	R:R:F20	R:R:F21	3.22	No	No	0	4	4
4	R:R:F20	R:R:L24	15.83	No	No	0	4	5
5	R:R:I73	R:R:M22	10.2	No	No	0	6	7
6	R:R:M22	R:R:W345	9.31	No	No	0	7	8
7	R:R:I29	R:R:V25	3.07	No	No	0	8	7
8	R:R:A26	R:R:I69	4.87	No	No	0	7	8
9	R:R:G65	R:R:I29	3.53	No	No	0	8	8
10	R:R:M30	R:R:V66	4.56	No	No	0	6	5
11	R:R:G32	R:R:L31	3.42	No	No	0	8	4
12	R:R:A58	R:R:N33	3.13	No	No	0	9	9
13	R:R:D61	R:R:N33	10.77	Yes	No	0	9	9
14	R:R:N33	R:R:P355	4.89	No	No	0	9	9
15	R:R:A58	R:R:V36	3.39	No	No	0	9	9
16	R:R:P359	R:R:V36	3.53	No	No	0	8	9
17	R:R:I37	R:R:I59	2.94	No	No	0	8	6
18	R:R:A39	R:R:F369	4.16	No	No	0	8	8
19	R:R:F40	R:R:R47	16.03	Yes	No	2	8	8
20	R:R:F40	R:R:S51	3.96	Yes	No	0	8	9
21	R:R:F40	R:R:Y52	4.13	Yes	No	2	8	6
22	R:R:F40	R:R:L55	6.09	Yes	No	0	8	7
23	R:R:I372	R:R:V42	6.14	No	No	0	6	6
24	R:R:D43	R:R:N45	12.12	No	No	0	7	6
25	R:R:D43	R:R:L46	6.79	No	Yes	0	7	9
26	R:R:K44	R:R:R47	7.43	No	No	0	7	8
27	R:R:L46	R:R:S51	3	Yes	No	0	9	9
28	R:R:L46	R:R:R364	3.64	Yes	No	0	9	7
29	R:R:R47	R:R:Y52	7.2	No	No	2	8	6
30	R:R:D111	R:R:R49	3.57	No	Yes	3	9	7
31	R:R:R49	R:R:Y122	4.12	Yes	No	3	7	8
32	R:R:F54	R:R:S50	3.96	Yes	No	0	8	8
33	R:R:I132	R:R:Y52	9.67	No	No	0	7	6
34	R:R:F53	R:R:L107	7.31	No	No	0	8	8
35	R:R:D111	R:R:F53	3.58	No	No	0	9	8
36	R:R:F54	R:R:I108	5.02	Yes	No	0	8	9
37	R:R:F54	R:R:Y358	3.09	Yes	Yes	0	8	9
38	R:R:F54	R:R:P359	5.78	Yes	No	0	8	8
39	R:R:F365	R:R:F54	8.57	No	Yes	0	8	8
40	R:R:N104	R:R:N56	12.26	Yes	No	0	8	9
41	R:R:M136	R:R:N56	12.62	No	No	0	8	9
42	R:R:N56	R:R:W140	7.91	No	Yes	0	9	9
43	R:R:D61	R:R:L57	4.07	Yes	No	0	9	9
44	R:R:L57	R:R:N104	4.12	No	Yes	0	9	8
45	R:R:I105	R:R:L57	4.28	No	No	0	9	9
46	R:R:A100	R:R:S60	3.42	No	No	4	8	9
47	R:R:N104	R:R:S60	2.98	Yes	No	0	8	9
48	R:R:S60	R:R:W140	7.41	No	Yes	4	9	9
49	R:R:D61	R:R:S101	4.42	Yes	No	0	9	9
50	R:R:D61	R:R:S351	5.89	Yes	No	0	9	9
51	R:R:D61	R:R:N354	5.39	Yes	No	0	9	9
52	R:R:F62	R:R:V66	5.24	No	No	0	8	5
53	R:R:F63	R:R:L97	3.65	No	No	0	6	6
54	R:R:G65	R:R:V64	3.68	No	No	0	8	8
55	R:R:L97	R:R:V64	5.96	No	No	0	6	8
56	R:R:I67	R:R:V66	6.14	No	No	0	6	5
57	R:R:I67	R:R:S68	3.1	No	No	0	6	8
58	R:R:S68	R:R:W90	3.71	No	Yes	0	8	7
59	R:R:D94	R:R:S68	7.36	No	No	0	8	8
60	R:R:I69	R:R:P70	3.39	No	No	0	8	9
61	R:R:L71	R:R:W90	3.42	No	Yes	0	5	7
62	R:R:T76	R:R:Y72	8.74	No	Yes	0	5	7
63	R:R:W90	R:R:Y72	8.68	Yes	Yes	0	7	7
64	R:R:E163	R:R:Y72	3.37	No	Yes	0	4	7
65	R:R:F344	R:R:Y72	6.19	Yes	Yes	0	6	7
66	R:R:I73	R:R:P74	5.08	No	No	0	6	5
67	R:R:H75	R:R:W80	4.23	No	No	0	6	9
68	R:R:F82	R:R:H75	20.36	Yes	No	0	6	6
69	R:R:E163	R:R:H75	3.69	No	No	0	4	6
70	R:R:L77	R:R:T76	4.42	Yes	No	0	6	5
71	R:R:F78	R:R:L77	3.65	No	Yes	0	5	6
72	R:R:F82	R:R:I86	3.77	Yes	No	0	6	5
73	R:R:C87	R:R:F82	5.59	No	Yes	0	9	6
74	R:R:C164	R:R:C87	7.28	No	No	0	9	9
75	R:R:V88	R:R:W157	3.68	No	Yes	0	7	6
76	R:R:F89	R:R:T93	6.49	No	No	0	4	5
77	R:R:L91	R:R:W90	5.69	No	Yes	0	6	7
78	R:R:L91	R:R:P166	4.93	No	Yes	0	6	7
79	R:R:I151	R:R:T92	4.56	No	No	0	7	6
80	R:R:L97	R:R:T93	2.95	No	No	0	6	5
81	R:R:D94	R:R:W348	10.05	No	Yes	1	8	8
82	L:L:?1	R:R:D94	4.56	Yes	No	1	0	8
83	R:R:N147	R:R:Y95	15.12	Yes	Yes	1	8	8
84	R:R:I151	R:R:Y95	6.04	No	Yes	0	7	8
85	R:R:P166	R:R:Y95	6.95	Yes	Yes	0	7	8
86	L:L:?1	R:R:Y95	18.91	Yes	Yes	1	0	8
87	R:R:T99	R:R:Y103	3.75	Yes	No	1	8	7
88	R:R:A143	R:R:T99	3.36	No	Yes	0	8	8
89	R:R:T99	R:R:V146	6.35	Yes	Yes	1	8	7
90	R:R:N147	R:R:T99	4.39	Yes	Yes	1	8	8
91	L:L:?1	R:R:T99	4.95	Yes	Yes	1	0	8
92	R:R:A100	R:R:W140	5.19	No	Yes	4	8	9
93	R:R:P186	R:R:V102	3.53	Yes	No	0	9	8
94	R:R:V102	R:R:W316	7.36	No	Yes	0	8	9
95	R:R:V146	R:R:Y103	3.79	Yes	No	1	7	7
96	R:R:N104	R:R:V139	2.96	Yes	No	0	8	8
97	R:R:I105	R:R:N354	5.66	No	No	0	9	9
98	R:R:I105	R:R:Y358	7.25	No	Yes	0	9	9
99	R:R:P186	R:R:V106	3.53	Yes	No	0	9	7
100	R:R:S109	R:R:V190	3.23	No	Yes	0	9	9
101	R:R:L114	R:R:Y110	11.72	No	No	0	5	6
102	R:R:F193	R:R:Y110	9.28	Yes	No	0	7	6
103	R:R:D111	R:R:Y122	8.05	No	No	3	9	8
104	R:R:R112	R:R:Y358	3.09	No	Yes	0	9	9
105	R:R:S117	R:R:Y113	10.17	No	No	0	7	9
106	R:R:F193	R:R:Y113	11.35	Yes	No	0	7	9
107	R:R:N196	R:R:Y113	4.65	No	No	0	6	9
108	R:R:S115	R:R:Y122	6.36	No	No	0	8	8
109	R:R:N118	R:R:S121	8.94	No	No	0	6	5
110	R:R:L130	R:R:V129	2.98	No	No	0	5	4
111	R:R:K131	R:R:T134	7.51	No	No	0	7	3
112	R:R:K131	R:R:L135	9.87	No	No	0	7	7
113	R:R:F144	R:R:G148	4.52	No	No	0	5	5
114	R:R:N147	R:R:V146	8.87	Yes	Yes	1	8	7
115	L:L:?1	R:R:V146	3	Yes	Yes	1	0	7
116	L:L:?1	R:R:N147	9.23	Yes	Yes	1	0	8
117	R:R:G148	R:R:P149	4.06	No	No	0	5	8
118	R:R:S154	R:R:W157	11.12	No	Yes	0	8	6
119	R:R:E165	R:R:P166	3.14	No	Yes	0	4	7
120	R:R:F168	R:R:P166	11.56	Yes	Yes	0	6	7
121	R:R:F168	R:R:F169	5.36	Yes	Yes	0	6	6
122	R:R:F168	R:R:I174	7.54	Yes	No	0	6	8
123	R:R:F169	R:R:L175	6.09	Yes	No	0	6	7
124	R:R:F169	R:R:Y340	3.09	Yes	Yes	0	6	5
125	L:L:?1	R:R:F169	4.09	Yes	Yes	0	0	6
126	R:R:E171	R:R:W172	7.63	No	No	0	6	4
127	R:R:I177	R:R:Y173	12.09	No	No	0	5	4
128	R:R:L175	R:R:T323	2.95	No	No	0	7	7
129	R:R:L175	R:R:S327	3	No	No	0	7	6
130	L:L:?1	R:R:T178	3.96	Yes	No	0	0	8
131	R:R:S179	R:R:S320	4.89	No	No	1	8	8
132	R:R:F180	R:R:L181	3.65	No	No	0	4	5
133	R:R:F180	R:R:V184	10.49	No	No	0	4	7
134	R:R:E182	R:R:F183	4.66	Yes	No	0	8	9
135	R:R:E182	R:R:W316	7.63	Yes	Yes	0	8	9
136	L:L:?1	R:R:E182	21.37	Yes	Yes	1	0	8
137	R:R:F183	R:R:V187	3.93	No	No	0	9	6
138	R:R:A317	R:R:F183	4.16	No	No	0	7	9
139	R:R:I185	R:R:P186	3.39	No	Yes	0	6	9
140	R:R:F312	R:R:P186	2.89	No	Yes	0	9	9
141	R:R:N194	R:R:V190	2.96	No	Yes	0	9	9
142	R:R:L309	R:R:V190	2.98	No	Yes	0	8	9
143	R:R:F193	R:R:Y192	5.16	Yes	No	0	7	5
144	R:R:N196	R:R:Y192	10.47	No	No	0	6	5
145	R:R:L305	R:R:N194	12.36	No	No	0	8	9
146	R:R:W199	R:R:Y198	4.82	No	Yes	0	4	7
147	R:R:W202	R:R:Y198	6.75	No	Yes	0	6	7
148	R:R:L201	R:R:L301	5.54	No	No	0	8	8
149	R:R:D205	R:R:E294	7.8	No	No	0	5	5
150	R:R:K303	R:R:R299	4.95	No	No	0	7	6
151	R:R:I307	R:R:K303	5.82	No	No	0	7	7
152	R:R:L308	R:R:L357	4.15	No	No	0	8	8
153	R:R:L308	R:R:Y358	3.52	No	Yes	0	8	9
154	R:R:C315	R:R:N350	4.72	No	No	0	8	9
155	R:R:Q347	R:R:W316	12.05	No	Yes	0	8	9
156	R:R:N350	R:R:W316	14.69	No	Yes	0	9	9
157	R:R:T323	R:R:Y319	8.74	No	Yes	1	7	7
158	R:R:Y319	R:R:Y340	7.94	Yes	Yes	1	7	5
159	R:R:A343	R:R:Y319	4	No	Yes	0	5	7
160	R:R:F344	R:R:Y319	10.32	Yes	Yes	1	6	7
161	R:R:Q347	R:R:Y319	3.38	No	Yes	1	8	7
162	L:L:?1	R:R:Y319	14.97	Yes	Yes	1	0	7
163	R:R:F322	R:R:L326	12.18	No	No	0	6	5
164	R:R:F322	R:R:Y340	6.19	No	Yes	0	6	5
165	R:R:T323	R:R:Y340	4.99	No	Yes	1	7	5
166	R:R:F328	R:R:Y329	17.54	No	No	0	5	5
167	R:R:G334	R:R:P335	4.06	No	No	0	1	4
168	R:R:K336	R:R:Y340	13.14	No	Yes	0	4	5
169	R:R:S337	R:R:W339	3.71	No	No	0	2	5
170	R:R:F344	R:R:W348	5.01	Yes	Yes	1	6	8
171	L:L:?1	R:R:F344	13.91	Yes	Yes	1	0	6
172	R:R:W345	R:R:W348	9.37	No	Yes	0	8	8
173	L:L:?1	R:R:Q347	14.31	Yes	No	1	0	8
174	L:L:?1	R:R:W348	10.71	Yes	Yes	1	0	8
175	R:R:F349	R:R:F352	5.36	No	No	0	4	6
176	R:R:F349	R:R:V353	3.93	No	No	0	4	7
177	R:R:N350	R:R:N354	12.26	No	No	0	9	9
178	R:R:H362	R:R:R364	12.41	No	No	0	9	7
179	R:R:F365	R:R:H362	3.39	No	No	0	8	9
180	R:R:K363	R:R:Q366	6.78	No	No	0	5	9
181	R:R:I185	R:R:L189	2.85	No	No	0	6	7
182	R:R:E165	R:R:T333	2.82	No	No	0	4	6
183	R:R:G167	R:R:W157	2.81	No	Yes	0	6	6
184	R:R:A28	R:R:F352	2.77	No	No	0	4	6
185	R:R:L31	R:R:L35	2.77	No	No	0	4	8
186	R:R:A302	R:R:Y198	2.67	No	Yes	0	7	7
187	R:R:C87	R:R:W157	2.61	No	Yes	0	9	6
188	R:R:C98	R:R:W316	2.61	No	Yes	0	8	9
189	R:R:C98	R:R:W348	2.61	No	Yes	0	8	8
190	R:R:F352	R:R:I29	2.51	No	No	0	6	8
191	R:R:F53	R:R:I108	2.51	No	No	0	8	9
192	R:R:F63	R:R:I59	2.51	No	No	0	6	6
193	R:R:I197	R:R:R112	2.51	No	No	0	9	9
194	R:R:F27	R:R:M30	2.49	No	No	0	5	6
195	R:R:F168	R:R:M150	2.49	Yes	No	0	6	7
196	R:R:V64	R:R:W348	2.45	No	Yes	0	8	8
197	R:R:D81	R:R:F82	2.39	No	Yes	0	3	6
198	R:R:D205	R:R:R297	2.38	No	No	0	5	7
199	R:R:Q125	R:R:R49	2.34	No	Yes	0	5	7
200	R:R:L301	R:R:Y198	2.34	No	Yes	0	8	7
201	R:R:K203	R:R:W202	2.32	No	No	0	6	6
202	R:R:L96	R:R:W140	2.28	No	Yes	0	6	9
203	R:R:H48	R:R:R49	2.26	No	Yes	0	7	7
204	R:R:A317	R:R:P318	1.87	No	No	0	7	9
205	R:R:G148	R:R:T92	1.82	No	No	0	5	6
206	R:R:C315	R:R:V311	1.71	No	No	0	8	6
207	R:R:L71	R:R:P70	1.64	No	No	0	5	9
208	R:R:A19	R:R:I73	1.62	No	No	0	5	6
209	R:R:S115	R:R:V116	1.62	No	No	0	8	8
210	R:R:S200	R:R:V116	1.62	No	No	0	6	8
211	R:R:A176	R:R:I324	1.62	No	No	0	6	6
212	R:R:V106	R:R:V190	1.6	No	Yes	0	7	9
213	R:R:V133	R:R:V137	1.6	No	No	0	3	4
214	R:R:V137	R:R:V141	1.6	No	No	0	4	4
215	R:R:A368	R:R:L46	1.58	No	Yes	0	8	9
216	R:R:A191	R:R:L309	1.58	No	No	0	5	8
217	R:R:A317	R:R:L321	1.58	No	No	0	7	6
218	R:R:I37	R:R:V41	1.54	No	No	0	8	3
219	R:R:I188	R:R:V184	1.54	No	No	0	4	7
220	R:R:I307	R:R:V311	1.54	No	No	0	7	6
221	R:R:I324	R:R:V325	1.54	No	No	0	6	6
222	R:R:I342	R:R:V338	1.54	No	No	0	5	1
223	R:R:F82	R:R:G83	1.51	Yes	No	0	6	7
224	R:R:L38	R:R:V42	1.49	No	No	0	4	6
225	R:R:L152	R:R:V88	1.49	No	No	0	5	7
226	R:R:N118	R:R:S117	1.49	No	No	0	6	7
227	R:R:L145	R:R:V141	1.49	No	No	0	4	4
228	R:R:N118	R:R:V120	1.48	No	No	0	6	7
229	R:R:L18	R:R:T17	1.47	No	No	0	5	3
230	R:R:E182	R:R:S179	1.44	Yes	No	1	8	8
231	R:R:E182	R:R:S320	1.44	Yes	No	1	8	8
232	R:R:I177	R:R:L181	1.43	No	No	0	5	5
233	R:R:E294	R:R:V293	1.43	No	No	0	5	5
234	R:R:L18	R:R:L77	1.38	No	Yes	0	5	6
235	R:R:A302	R:R:R299	1.38	No	No	0	7	6
236	R:R:L301	R:R:L305	1.38	No	No	0	8	8
237	R:R:E85	R:R:K84	1.35	No	No	0	3	3
238	R:R:L360	R:R:Q366	1.33	No	No	0	6	9
239	R:R:F193	R:R:S109	1.32	Yes	No	0	7	9
240	R:R:F369	R:R:V36	1.31	No	No	0	8	9
241	R:R:D81	R:R:E79	1.3	No	No	0	3	3
242	R:R:R123	R:R:T124	1.29	No	No	0	5	5
243	R:R:S330	R:R:Y329	1.27	No	No	0	2	5
244	R:R:F180	R:R:I185	1.26	No	No	0	4	6
245	R:R:D205	R:R:H206	1.26	No	No	0	5	5
246	R:R:S327	R:R:W172	1.24	No	No	0	6	4
247	R:R:F369	R:R:L35	1.22	No	No	0	8	8
248	R:R:L77	R:R:R15	1.21	Yes	No	0	6	3
249	R:R:L18	R:R:R341	1.21	No	No	0	5	6
250	R:R:F322	R:R:W339	1	No	No	0	6	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:F40	7.5525	4	2	8
2	R:R:L46	3.7525	4	0	9
3	R:R:R49	3.0725	4	3	7
4	R:R:F54	5.284	5	0	8
5	R:R:D61	6.108	5	0	9
6	R:R:Y72	6.745	4	0	7
7	R:R:L77	2.665	4	0	6
8	R:R:F82	6.724	5	0	6
9	R:R:W90	5.375	4	0	7
10	R:R:Y95	11.755	4	1	8
11	R:R:T99	4.56	5	1	8
12	R:R:N104	5.58	4	0	8
13	R:R:W140	5.6975	4	4	9
14	R:R:V146	5.5025	4	1	7
15	R:R:N147	9.4025	4	1	8
16	R:R:W157	5.055	4	0	6
17	R:R:P166	6.645	4	0	7
18	R:R:F168	6.7375	4	0	6
19	R:R:F169	4.6575	4	0	6
20	R:R:E182	7.308	5	1	8
21	R:R:P186	3.335	4	0	9
22	R:R:V190	2.6925	4	0	9
23	R:R:F193	6.7775	4	0	7
24	R:R:Y198	4.145	4	0	7
25	R:R:W316	8.868	5	0	9
26	R:R:Y319	8.225	6	1	7
27	R:R:Y340	7.07	5	1	5
28	R:R:F344	8.8575	4	1	6
29	R:R:W348	6.7	6	1	8
30	R:R:Y358	4.2375	4	0	9
31	L:L:?1	10.3308	12	1	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:F344	R:R:W348	19.8736	5.01	Yes	Yes	1	6	8
2	R:R:F344	R:R:Y72	69.9582	6.19	Yes	Yes	0	6	7
3	R:R:T76	R:R:Y72	22.2143	8.74	No	Yes	0	5	7
4	R:R:L77	R:R:T76	19.7179	4.42	Yes	No	0	6	5
5	R:R:V64	R:R:W348	15.1477	2.45	No	Yes	0	8	8
6	R:R:L71	R:R:P70	12.9183	1.64	No	No	0	5	9
7	R:R:L71	R:R:W90	17.2081	3.42	No	Yes	0	5	7
8	R:R:W90	R:R:Y72	13.5724	8.68	Yes	Yes	0	7	7
9	R:R:I67	R:R:S68	10.186	3.1	No	No	0	6	8
10	R:R:A58	R:R:N33	10.1727	3.13	No	No	0	9	9
11	R:R:D61	R:R:N33	12.7803	10.77	Yes	No	0	9	9
12	R:R:D61	R:R:N354	31.4035	5.39	Yes	No	0	9	9
13	R:R:N350	R:R:N354	91.0778	12.26	No	No	0	9	9
14	R:R:N350	R:R:W316	100	14.69	No	Yes	0	9	9
15	R:R:E182	R:R:W316	39.1331	7.63	Yes	Yes	0	8	9
16	L:L:?1	R:R:E182	38.7059	21.37	Yes	Yes	1	0	8
17	L:L:?1	R:R:F344	35.4931	13.91	Yes	Yes	1	0	6
18	R:R:Q347	R:R:W316	57.9343	12.05	No	Yes	0	8	9
19	L:L:?1	R:R:Q347	35.3685	14.31	Yes	No	1	0	8
20	R:R:Q347	R:R:Y319	22.6371	3.38	No	Yes	1	8	7
21	R:R:F344	R:R:Y319	18.5698	10.32	Yes	Yes	1	6	7
22	R:R:C98	R:R:W316	33.2681	2.61	No	Yes	0	8	9
23	R:R:C98	R:R:W348	33.188	2.61	No	Yes	0	8	8
24	R:R:I105	R:R:N354	59.6298	5.66	No	No	0	9	9
25	R:R:I105	R:R:Y358	45.7369	7.25	No	Yes	0	9	9
26	R:R:F54	R:R:Y358	39.6271	3.09	Yes	Yes	0	8	9
27	R:R:L46	R:R:S51	10.8313	3	Yes	No	0	9	9
28	R:R:L46	R:R:R364	16.9544	3.64	Yes	No	0	9	7
29	R:R:H362	R:R:R364	18.463	12.41	No	No	0	9	7
30	R:R:F365	R:R:H362	19.9626	3.39	No	No	0	8	9
31	R:R:F365	R:R:F54	21.2309	8.57	No	Yes	0	8	8
32	R:R:D111	R:R:F53	11.9571	3.58	No	No	0	9	8
33	R:R:F53	R:R:I108	15.032	2.51	No	No	0	8	9
34	R:R:F54	R:R:I108	16.5495	5.02	Yes	No	0	8	9
35	R:R:D61	R:R:L57	15.8642	4.07	Yes	No	0	9	9
36	R:R:L57	R:R:N104	28.9649	4.12	No	Yes	0	9	8
37	R:R:I105	R:R:L57	16.9411	4.28	No	No	0	9	9
38	R:R:N104	R:R:N56	11.6278	12.26	Yes	No	0	8	9
39	R:R:N104	R:R:S60	11.6278	2.98	Yes	No	0	8	9
40	R:R:D94	R:R:S68	19.9582	7.36	No	No	0	8	8
41	L:L:?1	R:R:D94	14.1821	4.56	Yes	No	1	0	8
42	R:R:E163	R:R:Y72	37.2909	3.37	No	Yes	0	4	7
43	R:R:E163	R:R:H75	34.9057	3.69	No	No	0	4	6
44	R:R:F82	R:R:H75	29.9973	20.36	Yes	No	0	6	6
45	R:R:C87	R:R:F82	17.5596	5.59	No	Yes	0	9	6
46	R:R:C87	R:R:W157	12.5178	2.61	No	Yes	0	9	6
47	L:L:?1	R:R:Y95	13.1141	18.91	Yes	Yes	1	0	8
48	R:R:V102	R:R:W316	49.6306	7.36	No	Yes	0	8	9
49	R:R:P186	R:R:V102	48.3046	3.53	Yes	No	0	9	8
50	R:R:P186	R:R:V106	34.6431	3.53	Yes	No	0	9	7
51	R:R:V106	R:R:V190	33.2369	1.6	No	Yes	0	7	9
52	R:R:S109	R:R:V190	18.8857	3.23	No	Yes	0	9	9
53	R:R:F193	R:R:S109	17.346	1.32	Yes	No	0	7	9
54	L:L:?1	R:R:F169	12.3799	4.09	Yes	Yes	0	0	6
55	R:R:I185	R:R:P186	12.8471	3.39	No	Yes	0	6	9
56	R:R:N194	R:R:V190	11.3653	2.96	No	Yes	0	9	9
57	R:R:C315	R:R:N350	15.2412	4.72	No	No	0	8	9
58	R:R:C315	R:R:V311	13.7104	1.71	No	No	0	8	6
59	R:R:I307	R:R:V311	12.1796	1.54	No	No	0	7	6
60	R:R:I307	R:R:K303	10.7022	5.82	No	No	0	7	7

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:D94	R:R:S68	7.36	1	No	No	8	8	1	2
R:R:F344	R:R:Y72	6.19	1	Yes	Yes	6	7	1	2
R:R:D94	R:R:W348	10.05	1	No	Yes	8	8	1	1
L:L:?1	R:R:D94	4.56	1	Yes	No	0	8	0	1
R:R:N147	R:R:Y95	15.12	1	Yes	Yes	8	8	1	1
R:R:I151	R:R:Y95	6.04	0	No	Yes	7	8	2	1
R:R:P166	R:R:Y95	6.95	0	Yes	Yes	7	8	2	1
L:L:?1	R:R:Y95	18.91	1	Yes	Yes	0	8	0	1
R:R:T99	R:R:Y103	3.75	1	Yes	No	8	7	1	2
R:R:A143	R:R:T99	3.36	0	No	Yes	8	8	2	1
R:R:T99	R:R:V146	6.35	1	Yes	Yes	8	7	1	1
R:R:N147	R:R:T99	4.39	1	Yes	Yes	8	8	1	1
L:L:?1	R:R:T99	4.95	1	Yes	Yes	0	8	0	1
R:R:V146	R:R:Y103	3.79	1	Yes	No	7	7	1	2
R:R:N147	R:R:V146	8.87	1	Yes	Yes	8	7	1	1
L:L:?1	R:R:V146	3	1	Yes	Yes	0	7	0	1
L:L:?1	R:R:N147	9.23	1	Yes	Yes	0	8	0	1
R:R:F168	R:R:P166	11.56	0	Yes	Yes	6	7	2	2
R:R:F168	R:R:F169	5.36	0	Yes	Yes	6	6	2	1
R:R:F169	R:R:L175	6.09	0	Yes	No	6	7	1	2
R:R:F169	R:R:Y340	3.09	0	Yes	Yes	6	5	1	2
L:L:?1	R:R:F169	4.09	1	Yes	Yes	0	6	0	1
R:R:L175	R:R:T323	2.95	0	No	No	7	7	2	2
L:L:?1	R:R:T178	3.96	1	Yes	No	0	8	0	1
R:R:S179	R:R:S320	4.89	1	No	No	8	8	2	2
R:R:E182	R:R:F183	4.66	1	Yes	No	8	9	1	2
R:R:E182	R:R:W316	7.63	1	Yes	Yes	8	9	1	2
L:L:?1	R:R:E182	21.37	1	Yes	Yes	0	8	0	1
R:R:Q347	R:R:W316	12.05	1	No	Yes	8	9	1	2
R:R:T323	R:R:Y319	8.74	1	No	Yes	7	7	2	1
R:R:Y319	R:R:Y340	7.94	1	Yes	Yes	7	5	1	2
R:R:A343	R:R:Y319	4	0	No	Yes	5	7	2	1
R:R:F344	R:R:Y319	10.32	1	Yes	Yes	6	7	1	1
R:R:Q347	R:R:Y319	3.38	1	No	Yes	8	7	1	1
L:L:?1	R:R:Y319	14.97	1	Yes	Yes	0	7	0	1
R:R:T323	R:R:Y340	4.99	1	No	Yes	7	5	2	2
R:R:F344	R:R:W348	5.01	1	Yes	Yes	6	8	1	1
L:L:?1	R:R:F344	13.91	1	Yes	Yes	0	6	0	1
R:R:W345	R:R:W348	9.37	0	No	Yes	8	8	2	1
L:L:?1	R:R:Q347	14.31	1	Yes	No	0	8	0	1
L:L:?1	R:R:W348	10.71	1	Yes	Yes	0	8	0	1
R:R:C98	R:R:W316	2.61	0	No	Yes	8	9	2	2
R:R:C98	R:R:W348	2.61	0	No	Yes	8	8	2	1
R:R:V64	R:R:W348	2.45	0	No	Yes	8	8	2	1
R:R:E182	R:R:S179	1.44	1	Yes	No	8	8	1	2
R:R:E182	R:R:S320	1.44	1	Yes	No	8	8	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	8JXW_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	2.89
Number of Linked Nodes	238
Number of Links	250
Number of Hubs	31
Number of Links mediated by Hubs	119
Number of Communities	4
Number of Nodes involved in Communities	25
Number of Links involved in Communities	35

Path Summary
Number Of Nodes in MetaPath	61
Number Of Links MetaPath	60
Number of Shortest Paths	41233
Length Of Smallest Path	3
Average Path Length	12.6506
Length of Longest Path	25
Minimum Path Strength	1.265
Average Path Strength	6.77811
Maximum Path Strength	20.14
Minimum Path Correlation	0.7
Average Path Correlation	0.920533
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	4.34783
Average % Of Corr. Nodes	51.9853
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	40.6138
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• D2 dopamine receptor binding • protein binding • binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • phosphorus-oxygen lyase activity • enzyme regulator activity • cyclase regulator activity • molecular function regulator activity • cyclase activity • adenylate cyclase regulator activity • lyase activity • catalytic activity • adenylate cyclase activity • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • cation binding • magnesium ion binding • metal ion binding • GDP binding • G protein-coupled serotonin receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • cell communication • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction
Gene Ontology	Biological Process	• cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • cell communication • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • response to hormone • response to chemical • response to endogenous stimulus • response to peptide hormone • response to oxygen-containing compound • response to nitrogen compound • cell division • leukocyte migration • immune system process • mononuclear cell migration • lymphocyte migration • cell migration • T cell migration • cell motility • regulation of steroid biosynthetic process • regulation of cholesterol biosynthetic process • regulation of cholesterol metabolic process • steroid metabolic process • regulation of lipid metabolic process • sterol metabolic process • positive regulation of biological process • cholesterol metabolic process • lipid biosynthetic process • alcohol metabolic process • regulation of primary metabolic process • positive regulation of metabolic process • regulation of small molecule metabolic process • positive regulation of biosynthetic process • positive regulation of lipid metabolic process • small molecule metabolic process • steroid biosynthetic process • positive regulation of cellular process • regulation of biosynthetic process • secondary alcohol biosynthetic process • regulation of alcohol biosynthetic process • small molecule biosynthetic process • regulation of steroid metabolic process • cholesterol biosynthetic process • positive regulation of cholesterol biosynthetic process • primary metabolic process • secondary alcohol metabolic process • positive regulation of steroid biosynthetic process • biosynthetic process • sterol biosynthetic process • positive regulation of lipid biosynthetic process • regulation of sterol biosynthetic process • alcohol biosynthetic process • positive regulation of cholesterol metabolic process • positive regulation of steroid metabolic process • metabolic process • regulation of lipid biosynthetic process • positive regulation of small molecule metabolic process • regulation of metabolic process • positive regulation of alcohol biosynthetic process • positive regulation of sterol biosynthetic process • lipid metabolic process • regulation of cytoskeleton organization • regulation of cellular component organization • microtubule cytoskeleton organization • regulation of mitotic spindle organization • mitotic cell cycle • cellular component organization • cell cycle • cellular component organization or biogenesis • regulation of cell cycle • microtubule cytoskeleton organization involved in mitosis • spindle organization • cell cycle process • regulation of cell cycle process • regulation of microtubule-based process • regulation of spindle organization • regulation of organelle organization • mitotic spindle organization • organelle organization • mitotic cell cycle process • microtubule-based process • cytoskeleton organization • regulation of microtubule cytoskeleton organization • protein localization • positive regulation of protein localization to cell periphery • regulation of localization • protein localization to cell periphery • cellular localization • regulation of protein localization • positive regulation of protein localization to cell cortex • regulation of protein localization to cell periphery • localization • regulation of cellular localization • regulation of protein localization to cell cortex • cellular macromolecule localization • macromolecule localization • positive regulation of protein localization • protein localization to cell cortex • response to ketone • response to prostaglandin • response to lipid • response to alcohol • response to prostaglandin E • cellular response to forskolin • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to alcohol • response to forskolin • cellular response to lipid • cellular response to ketone • midbody • cellular anatomical structure • membrane-bounded organelle • intracellular anatomical structure • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • intracellular membrane-bounded organelle • nucleolus • intracellular organelle lumen • intracellular organelle • organelle lumen • organelle • membraneless organelle
Gene Ontology	Cellular Component	• midbody • cellular anatomical structure • membrane-bounded organelle • intracellular anatomical structure • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • intracellular membrane-bounded organelle • nucleolus • intracellular organelle lumen • intracellular organelle • organelle lumen • organelle • membraneless organelle • nuclear lumen • cell periphery • cell cortex • cytoplasm • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular region • extracellular space • vesicle • extracellular membrane-bounded organelle • centrosome • microtubule organizing center • cytoskeleton • microtubule cytoskeleton • centriolar satellite • cytosol • nucleoplasm • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • organelle membrane • lysosome • Golgi apparatus • endomembrane system • cilium • plasma membrane bounded cell projection • ciliary basal body • cell projection • protein binding • binding • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular process • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • signal transduction • cell communication • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • response to oxygen-containing compound • cellular response to oxygen-containing compound • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to chemical stimulus • cellular response to alcohol • response to hormone • response to chemical • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • photoreceptor cell cilium • synapse • cell junction • G-protein beta-subunit binding • fibroblast proliferation • neurotransmitter receptor activity • molecular transducer activity • signaling receptor activity • G protein-coupled amine receptor activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • histamine receptor activity • positive regulation of cytosolic calcium ion concentration • regulation of biological quality • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway • trans-synaptic signaling • anterograde trans-synaptic signaling • chemical synaptic transmission • regulation of signaling • regulation of signal transduction • regulation of MAPK cascade • regulation of intracellular signal transduction • regulation of response to stimulus • MAPK cascade • regulation of cell communication • defense response • response to stress • inflammatory response • G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger • somatodendritic compartment • dendrite • dendritic tree
SCOP2	Domain Identifier	• Ras-like P-loop GTPases • Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Ras-like P-loop GTPases • Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	VCF
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	VCF
Name	2-chloranyl-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine
Synonyms	VUF-6884
Identifier
Formula	C18 H18 Cl N3 O
Molecular Weight	327.808
SMILES
PubChem	11846300
Formal Charge	0
Total Atoms	41
Total Chiral Atoms	0
Total Bonds	44
Total Aromatic Bonds	12


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q9H3N8
Sequence	>8JXW_nogp_Chain_R L S T R V T L A F F M S L V A F A I M L G N A L V I L A F V V D K N L R H R S S Y F F L N L A I S D F F V G V I S I P L Y I P H T L F E W D F G K E I C V F W L T T D Y L L C T A S V Y N I V L I S Y D R Y L S V S N A V S Y R T Q H T G V L K I V T L M V A V W V L A F L V N G P M I L V S E S W S E C E P G F F S E W Y I L A I T S F L E F V I P V I L V A Y F N M N I Y W S L W K R D H V E L L R A R R L A K S L A I L L G V F A V C W A P Y S L F T I V L S F Y S S A T G P K S V W Y R I A F W L Q W F N S F V N P L L Y P L C H K R F Q K A F L K I Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8YNA	A	Amine	Histamine	H₄	Homo sapiens	Immepip	-	Gi1/β1/γ	2.63	2024-10-16	10.2210/pdb8YN7/pdb
	8YNA (No Gprot)	A	Amine	Histamine	H₄	Homo sapiens	Immepip	-		2.63	2024-10-16	10.2210/pdb8YN7/pdb
	8YN9	A	Amine	Histamine	H₄	Homo sapiens	Histamine	-	Gi1/β1/γ2	2.3	2024-10-09	doi.org/10.1038/s41467-024-52585-y
	8YN9 (No Gprot)	A	Amine	Histamine	H₄	Homo sapiens	Histamine	-		2.3	2024-10-09	doi.org/10.1038/s41467-024-52585-y
	8TH4	A	Peptide	Angiotensin	AT₁	Homo sapiens	Losartan	AT118-L Nanobody	-	3.3	2024-05-22	10.1038/s41589-024-01620-6
	8JXX	A	Amine	Histamine	H₄	Homo sapiens	Clobenpropit	-	Gi1/β1/γ2	3.06	2024-03-20	10.1038/s41467-024-46840-5
	8JXX (No Gprot)	A	Amine	Histamine	H₄	Homo sapiens	Clobenpropit	-		3.06	2024-03-20	10.1038/s41467-024-46840-5
	8JXW	A	Amine	Histamine	H₄	Homo sapiens	VUF6884	-	Gi1/β1/γ2	3.01	2024-03-20	10.1038/s41467-024-46840-5
	8JXW (No Gprot)	A	Amine	Histamine	H₄	Homo sapiens	VUF6884	-		3.01	2024-03-20	10.1038/s41467-024-46840-5
	8JXV	A	Amine	Histamine	H₄	Homo sapiens	Clozapine	-	Gi1/β1/γ2	3.21	2024-03-20	10.1038/s41467-024-46840-5
	8JXV (No Gprot)	A	Amine	Histamine	H₄	Homo sapiens	Clozapine	-		3.21	2024-03-20	10.1038/s41467-024-46840-5
	8JXT	A	Amine	Histamine	H₄	Homo sapiens	Histamine	PO4	Gi1/β1/γ2	3.07	2024-03-20	10.1038/s41467-024-46840-5
	8JXT (No Gprot)	A	Amine	Histamine	H₄	Homo sapiens	Histamine	PO4		3.07	2024-03-20	10.1038/s41467-024-46840-5
	8HOC	A	Amine	Histamine	H₄	Homo sapiens	Imetit	-	Gi1/β1/γ2	3	2023-12-20	To be published
	8HOC (No Gprot)	A	Amine	Histamine	H₄	Homo sapiens	Imetit	-		3	2023-12-20	To be published
	8HN8	A	Amine	Histamine	H₄	Homo sapiens	Histamine	-	Gi1/β1/γ2	3	2023-12-20	To be published
	8HN8 (No Gprot)	A	Amine	Histamine	H₄	Homo sapiens	Histamine	-		3	2023-12-20	To be published
	7YFD	A	Amine	Histamine	H₄	Homo sapiens	Imetit	-	chim(NtGi1-Gs-CtGq)/β1/γ2	3.1	2023-10-25	10.1038/s41467-023-42260-z
	7YFD (No Gprot)	A	Amine	Histamine	H₄	Homo sapiens	Imetit	-		3.1	2023-10-25	10.1038/s41467-023-42260-z
	7YFC	A	Amine	Histamine	H₄	Homo sapiens	Histamine	-	chim(NtGi1-Gs-CtGq)/β1/γ2	3	2023-10-25	10.1038/s41467-023-42260-z
	7YFC (No Gprot)	A	Amine	Histamine	H₄	Homo sapiens	Histamine	-		3	2023-10-25	10.1038/s41467-023-42260-z
	8H4L	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	Doconexent	-	chim(NtGi1-Gs-CtGq)/β1/γ2	3.07	2023-06-21	10.1038/s41422-023-00835-x
	8H4L (No Gprot)	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	Doconexent	-		3.07	2023-06-21	10.1038/s41422-023-00835-x
	8H4K	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	GW9508	-	chim(NtGi1-Gs-CtGq)/β1/γ2	3.1	2023-06-21	10.1038/s41422-023-00835-x
	8H4K (No Gprot)	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	GW9508	-		3.1	2023-06-21	10.1038/s41422-023-00835-x
	8H4I	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	Doconexent	-	chim(NtGi1-Gs)/β1/γ2	3.06	2023-06-21	10.1038/s41422-023-00835-x
	8H4I (No Gprot)	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	Doconexent	-		3.06	2023-06-21	10.1038/s41422-023-00835-x
	8KH4	A	Orphan	Orphan	GPR161	Homo sapiens	-	-	Gs/β1/γ2	3.1	2023-10-11	10.1038/s41467-023-41654-3
	8KH4 (No Gprot)	A	Orphan	Orphan	GPR161	Homo sapiens	-	-		3.1	2023-10-11	10.1038/s41467-023-41654-3
	6WH4	A	Amine	5-Hydroxytryptamine	5-HT_2A	Homo sapiens	Methiothepin	-	-	3.4	2020-09-23	10.1016/j.cell.2020.08.024
	6WH4 (Multimeric)	A	Amine	5-Hydroxytryptamine	5-HT_2A	Homo sapiens	Methiothepin	-		3.4	2020-09-23	10.1016/j.cell.2020.08.024

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